KNAUER Eurospher II 100 CN (U)HPLC Columns for NP & RP (USP L10)

Cyano or CN for Normal Phase and Reversed Phase (USP L10)

CN is one of the most versatile stationary phases that can be used in reversed phase mode as well as in normal phase mode. The cyano modification supports the π-π interaction as well as polar and hydrophobic interactions with low polarity solvents. These phases are preferred for compounds with double bonds and aromatic groups. Cyano bonded phases show unique selectivity for polar compounds and are more suitable than bare silica for normal phase (NP) gradient separations. The cyano functional group is a strong dipole that can interact with other dipoles or induce dipoles on solutes. These phases also exhibit moderate hydrophobicity due to the alkyl linker.

Due to the quick equilibration time of the CN bonded phase, it is the best choice for gradient elution in normal phase mode. CN phases can be used as a less polar alternative to Si phases.

The material is typically preferred for:

• Compounds with double bonds
• Cyclic antidepressants

KNAUER: CN

Stationary phase Eurospher II 100 CN is provided in these column types: analytical, semi-preparative and preparative.

Eurospher II 100 CN Analytical Columns are available with these parameters:

• Column length (mm): 50, 100, 150, 250
• Column ID (mm): 3, 4, 4.6
• Particle size (µm): 3, 5

Eurospher II 100 CN Semi-Preparative Standard Columns are available with these parameters:

• Column length (mm): 30, 50, 125, 150, 250
• Column ID (mm): 8, 16
• Particle size (µm): 5, 10

KNAUER (U)HPLC Columns

Widest range of HPLC and UHPLC columns for all separation modes and applications.

• Safe Investment: Robust and reliable columns for attractive price 
• Separation Mode: Reversed Phase, HILIC, Normale
• Simplicity: Easy purchase via our online store with fast delivery
• Application: All-rounder for research or highly specialised for high-throughput analysis? We have the best column for your requirements.
• Flexibility: Wide selection of column and particle sizes, for (U)HPLC applications up to 1000 bar

KNAUER offers the perfect column for any small molecule separation. No matter which separation mode, molecule and the mobile phase, we offer a suitable (U)HPLC stationary phase. Choose from a wide range of modifications, particle sizes and column dimensions to suit your application. To elongate the lifetime of your column, you can choose to use a suitable precolumn.

KNAUER: KNAUER (U)HPLC Columns