33 1 3048 7200Improving the reproducibility, method transfer, and processing efficiency of solid-phase extraction (SPE) sample preparation is challenging, and addressing it starts with your solutions. Achieve high-quality sample preparation and extraction by reducing user variability with the programmed pressure profiles and methods on the Otto SPEcialist Positive Pressure Manifold.
Controlled by an interfaced tablet, the easy-to-use Otto software simplifies solid-phase extraction method development and transfer, positive pressure optimization, and real-time manipulation of pressure profiles to further improve method robustness. The Otto SPEcialist Positive Pressure Manifold is a semi-automated system designed for use with both SPE plates and cartridges, including µElution and macro elution plates and 1 cc, 3 cc, and 6 cc cartridges.
To improve reproducibility and analytical consistency during sample preparation and solid-phase extraction.
Waters Otto SPEcialist: The Otto Specialist Positive Pressure Manifold is designed to improve analytical consistency during sample preparation and solid-phase extraction.
The Otto SPEcialist Positive Pressure Manifold is controlled by the easy-to-use Otto Software. The touchscreen interface requires little-to-no training for novice and expert SPE users. Easily create pressure profiles with optimized flow rates for each step of your process. Whether it’s a simple “load, wash, elute” or a more complicated workflow with multiple steps, Otto Software makes running programed methods simple.
Waters Otto SPEcialist: Pressure profile example created in the Otto SPEcialist software designed to increase pressure over time.
Running programmed methods, including a combination of pressure profiles and manifold commands, eliminates user-to-user variability ensuring consistency across users and labs. Otto Software tracks and documents each pressure profile and method processed, ensuring workflow consistency.
Waters Otto SPEcialist: Method set-up on an Otto SPEcialist System incorporating opening and closing of the manifold, pausing the method, and running a pressure profile.
Reproducibility is especially important when generating calibration curves. With its programmable pressure profiles and methods, Otto SPEcialist Positive Pressure Manifold performs consistently across all SPE runs, independent of user expertise.
Waters Otto SPEcialist: Calibration curves for sulfadimethoxine generated on a vacuum manifold and Otto SPEcialist by a novice user. Replicates (n=3) of each level of the curve were run and standard deviations were determined and are indicated error bars. The Otto SPEcialist error bars, while present are very small and difficult to discern.
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