<p><strong>We are pleased to announce that a maintenance release is now available for KnowItAll 2025.</strong></p><p>Maintenance releases are an important way to introduce improvements and bug fixes between major releases to make sure users get the most out of KnowItAll solutions.</p><p>Late 2024, we announced the KnowItAll 2025 major release featuring the <strong>new LC Expert tool</strong>, <strong>KnowItAll Data Control</strong>, <strong>KnowItAll Drug Classification Models</strong>, and various advances for spectral analysis workflows. This is the first update available after that release.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Wiley_Know_It_All_LC_Expert_Streamline_component_identification_with_the_power_of_the_new_Know_It_All_LC_Expert_s_automated_workflow_84a090a7c2.jpg" alt="Wiley: NEW! KnowItAll LC Expert: Streamline component identification with the power of the new KnowItAll LC Expert’s automated workflow." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Wiley_Know_It_All_LC_Expert_Streamline_component_identification_with_the_power_of_the_new_Know_It_All_LC_Expert_s_automated_workflow_84a090a7c2.jpg 245w," sizes="100vw" width="1735" height="960"></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Wiley_Know_It_All_drug_classification_models_25277cc5e0.jpg" alt="Wiley: NEW! KnowItAll drug classification models." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Wiley_Know_It_All_drug_classification_models_25277cc5e0.jpg 245w," sizes="100vw" width="603" height="324"></p><p>We encourage users to ensure they are using the most recent version of the software for best performance.</p><blockquote><p><strong>Current users can </strong><a target="_blank" rel="noopener noreferrer" href="https://get.knowitall.com/Download?_gl=1*18h0vjr*_gcl_au*Mjk3ODY0Mzg1LjE3MTMyNzcyMDEuMTkwNDkyNDI4NS4xNzEzMzY3NDc0LjE3MTMzNjc0Nzk."><strong>download the most recent version here</strong></a><strong>.</strong></p></blockquote><h4><strong>Learn more about KnowItAll 2025:&nbsp;</strong>&nbsp;</h4><ul><li><a target="_blank" rel="noopener noreferrer" href="https://sciencesolutions.wiley.com/whats-new-in-knowitall-2025/"><strong>What's New&nbsp;</strong></a> &nbsp;&nbsp;</li><li><a target="_blank" rel="noopener noreferrer" href="https://sciencesolutions.wiley.com/knowitall-version-history/"><strong>Version History</strong></a></li></ul><h4><strong>About KnowItAll</strong></h4><p>KnowItAll Software offers solutions to analyze and manage multiple types of spectral and chemical data in multiple file and instrument formats. KnowItAll's integrated toolsets eliminate the need for multiple software packages and increase overall lab efficiency and staff proficiency. Combined with Wiley’s comprehensive, high-quality spectral reference libraries, it provides an unparalleled solution for fast, reliable spectral analysis.</p><h4><strong>About Wiley</strong></h4><p>Wiley (NYSE: WLY) is one of the world’s largest publishers and a trusted leader in research and learning. Our industry-leading content, services, platforms, and knowledge networks are tailored to meet the evolving needs of our customers and partners, including researchers, students, instructors, professionals, institutions, and corporations. We empower knowledge-seekers to transform today’s biggest obstacles into tomorrow’s brightest opportunities. For more than two centuries, Wiley has been delivering on its timeless mission to unlock human potential. Visit us at <a target="_blank" rel="noopener noreferrer" href="https://www.wiley.com/en-ie"><strong>Wiley.com</strong></a>.&nbsp;</p>

KnowItAll 2025 Maintenance Release 2025.1 Available

<p><strong>SIELC has developed the first and only HPLC software that is accessible via the cloud - </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1250"><strong>HPLC.cloud</strong></a><strong>.</strong></p><h4><strong>&nbsp;Special Features:</strong></h4><ul><li><strong>Cloud Integration:</strong> Real-time data streaming and storage on HPLC.cloud ensure your experiment data is always backed up and accessible.</li><li><strong>Remote Access:</strong> Control and monitor your system from anywhere — lab, office, or on the go — using a PC, tablet, or phone.</li><li><strong>Data Security:</strong> All your results are stored in a centralized, secure location — so no data is ever lost.</li><li><strong>Sync Capabilities:</strong> Chromatograms are synced with HPLC.cloud every second, providing real-time experiment updates.</li></ul><h4><strong>Key Functionality:</strong></h4><ul><li><strong>Real-time Chromatogram Streaming:</strong> Watch live data as it’s being collected.</li><li><strong>Sequence Building and Recording:</strong> Build, record, and store experiment sequences.</li><li><strong>Method Storage: </strong>Save and reuse methods for consistency and efficiency.</li><li><strong>Data Accessibility:</strong> Store all your sample and result data securely in the cloud, accessible anytime.</li><li><strong>Remote Control: </strong>Start, stop, or modify analyses from any internet-connected device.</li><li><strong>Comprehensive Data Analysis: </strong>Calibrate, analyze, and quantify directly within the cloud interface.</li><li><strong>Mobile and PC Access: </strong>Use on PC, tablet, or smartphone for maximum flexibility.</li><li><strong>Online Data Search: </strong>Easily search and access your data from anywhere.</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/SIELC_SIELC_Software_HPLC_cloud_1_441d304d5d.jpg" alt="SIELC: SIELC Software – HPLC.cloud" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_SIELC_SIELC_Software_HPLC_cloud_1_441d304d5d.jpg 225w," sizes="100vw" width="801" height="554"></p><p>No software installation. No USBs. No data loss.</p>

How to Use HPLC Cloud - A Complete Guide

News from LabRulezLCMS Library - Week 20, 2025

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Watrex Streamline OLE 200 On-line SPE system

An automatic on-line solid-phase extraction (SPE) and pre-concentration unit with a 10-port selection valve processes up to 7 samples through 7 SPE cartridges. After washing, the eluted components are directed into an HPLC system via a sample valve. 

<p>Automatic on-line SPE/pre-concentration unit equipped with <strong>10 port selection valve</strong> for samples and washing solvents, high pressure cartridge selector for 7 cartridges, high pressure pump, and injection valve connected to HPLC instrument.</p><p>The pump sucks through 10 port selection valve <strong>up to 7 samples to 7 SPE cartridges</strong>. Then collected components are washed with one or two slushing eluents, and eluted via sample valve into a HPLC system.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Watrex_Watrex_Streamline_OLE_200_On_line_SPE_system_Principle_of_online_SPE_by_OLE_200_e40db78c8f.jpg" alt="Watrex - Watrex Streamline OLE 200 On-line SPE system - Principle of online SPE by OLE 200"></p><h3><strong>TECHNICAL SPECIFICATION</strong></h3><ul><li><strong>Cartridge selector:</strong> twin 10-port high pressure selector, 40MPa</li><li><strong>Cartridge dimensions:</strong> 10x4mm</li><li><strong>Connection to HPLC instrument:</strong> Rheodyne 6 port sample valve</li><li><strong>Selector:</strong> low-pressure 10-port selection valve IDEX</li><li><strong>Sample load pump:</strong> high-pressure single piston ss pump</li><li><strong>Instrument control:</strong> driver for all valves and pump controll included</li></ul><h3><strong>Ordering information:</strong></h3><h5><strong>PN/Component:</strong></h5><ul><li><strong>D2K2062401</strong> Watrex OLE200</li></ul><p><strong>You can also visit this product on the </strong><a target="_blank" rel="noopener noreferrer" href="https://watrex.com/obchod/laboratory-automation/streamline-ole-200/?utm_source=labrulez&amp;utm_medium=propagace&amp;utm_campaign=labrulez_produkty"><strong>Watrex website</strong></a><strong>.</strong></p>

Watrex xTrovert XT Automatic DNA/RNA extractor

Watrex xTrovert XT is an automatic DNA/RNA extractor. It streamlines the extraction process, making it more efficient and reproducible.

<p><strong>Automatic extractor utilises a simple principle of two pipetting heads serving a 96-well plate.</strong></p><p>Thanks to easy replacement head options of pipetting with <strong>300 μl tips</strong> or <strong>1000 μl</strong> tips are available. <strong>Automatic optical sensor calibration</strong> enables the use of pipetting tips and <strong>96-well plates</strong> from virtually any supplier. The device is equipped with two magnetic arms for protocols including paramagnetic SPR beads. It also allows for thermal incubation in the range of <strong>25 to 85 °C</strong>. In addition to internal <strong>LED lighting</strong>, the station is equipped with an integrated <strong>UV-C sterilisation unit</strong>. Intuitive control from <strong>TFT touch panel</strong> user interface facilitates easy set-up. xTrovert™ XT is a <strong>fully programmable open system</strong> where user can create their own workflow scripts downloadable as text files from USB flas disk.</p><h3><strong>APPLICATIONS</strong></h3><ul><li><strong>Sample prep for PCR testing</strong></li><li><strong>NGS library prep</strong></li><li><strong>Sanger DNA sequencing</strong></li></ul><h3><strong>CURRENT PROTOCOLS</strong></h3><ul><li><strong>DNA/RNA extraction</strong></li><li><strong>DNA purification</strong></li><li><strong>PCR clean-up/desalting</strong></li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Watrex_Watrex_x_Trovert_XT_Automatic_DNA_RNA_extractor_Compatible_with_any_magnetic_bead_based_kit_23886eea52.jpg" alt="Watrex: Watrex xTrovert XT Automatic DNA/RNA extractor - Compatible with any magnetic bead based kit"></p><h3><strong>TECHNICAL SPECIFICATION</strong></h3><ul><li><strong>Capacity:</strong> 16 or 32 samples/run</li><li><strong>Volume range:</strong> 10 – 600 μl</li><li><strong>Temperature:</strong> 25 – 85 °C</li><li><strong>Sterilization:</strong> UV-C</li><li><strong>Display:</strong> 3,5“ TFT touch display</li><li><strong>Connectivity:</strong> USB 1.0/2.0</li><li><strong>Power source:</strong> 24 V adaptor</li><li><strong>Dimensions in cm:</strong> 65(w) x 65(h) x 34(d)</li><li><strong>Weight:</strong> 25 kg</li></ul><h3><strong>Ordering information:</strong></h3><h5><strong>PN/Component:</strong></h5><ul><li><strong>XTR000-001</strong> xTrovert™ XT Universal robotic pipettor for DNA/RNA extraction &amp; handling</li><li><strong>XTR000-003</strong> Replaceable 8-channel 1000uL pipetting head for xTrovert™ XT</li><li><strong>XTR000-004</strong> Replaceable 8-channel 300uL pipetting head for xTrovert™ XT</li><li><strong>XTR000-100</strong> Deepwell plates (empty) for xTrovert™ XT</li><li><strong>XTR000-220</strong> DNA/RNA extraction kit, mgn. beads, 16-rxns per plate</li></ul><p>The entire system was designed and developed by Watrex Praha and is <strong>manufactured in the Czech Republic</strong> and promises a shift in the performance and efficiency of laboratory processes worldwide!</p><p><strong>You can also visit this product on the </strong><a target="_blank" rel="noopener noreferrer" href="https://watrex.com/obchod/laboratory-automation/xtrovert-xt/?utm_source=labrulez&amp;utm_medium=propagace&amp;utm_campaign=labrulez_produkty"><strong>Watrex website</strong></a><strong>.</strong></p>

SIELC Alltesta Mini HPLC Autosampler

The Alltesta™ Mini Autosampler is an affordable and dependable solution for automated sample handling in various analytical and liquid handling applications, including HPLC.

<p><strong>The Alltesta™ Mini Autosampler is an affordable and dependable solution for automated sample handling in various analytical and liquid handling applications, including HPLC. With its proprietary alpha/beta mechanical design, this compact autosampler offers direct and comprehensive control of its features, making integration quick and easy. Users can tailor the mini autosampler to their needs with customizable valve configurations, tray designs, and syringe volumes and pressures. Additionally, a built-in shaking feature enables sample mixing before injection and/or simple sample extraction within the vial.</strong></p>
<p>This compact autosampler comes designed with original equipment manufacturer (OEM) customization in mind. Custom shape, color, and communication interfaces can be adapted to integrate with any system. Comprehensive software integration support is provided. Other options include metal-free sampling and reagent addition and mixing capabilities.</p>
<ul>
<li><p><strong>FRACTION COLLECTION CAPABILITY:</strong> A simple software modification can quickly convert this small autosampler into a fraction collector.</p>
</li>
<li><p><strong>REACTOR PROBE SAMPLER CAPABILITY:</strong> A simple software modification can quickly convert this small autosampler into a reactor probe sampler.</p>
</li>
</ul>
<p>This miniature autosampler can also be used as a component of our <a href="https://lcms.labrulez.com/products/1242"><strong>Alltesta™ Gradient Automated Analyzer</strong></a> and <a href="https://lcms.labrulez.com/products/1243"><strong>Alltesta™ Cromite Analyzer</strong></a>.</p>
<blockquote>
<h4><strong>The price of the Alltesta™ Mini Autosampler varies depending on the specific configuration requested.</strong></h4>
</blockquote>
<h4><strong>Specifications</strong></h4>
<ul>
<li>Dimensions (WHL): 160 x 145 x 195 mm / 6.3 x 5.71 x 7.68 in</li>
<li>Weight: 3 kg / 6.6 lb</li>
<li>Power: 24 V</li>
<li>Capacity: 48 vials or 96-well plate</li>
<li>Pressure: 5000 psi</li>
<li>Needle Wash: Inside and outside</li>
<li>Syringe Capacity: 120µL high-pressure / 4000µL low-pressure stainless / 4000µL low-pressure ceramic</li>
<li>Valve options: 6×2, 7×6 and 10×9 (more details here).</li>
<li>Volume Accuracy: 0.1µL</li>
<li>Communication: RS232 Virtual COM port via USB</li>
</ul>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/SIELC_Alltesta_Mini_Autosampler_A_very_simple_schematic_operation_of_the_Alltesta_Autosampler_b79b0ad187.jpg" alt="SIELC: Alltesta™ Mini Autosampler - A very simple schematic operation of the Alltesta™ Autosampler."/></p>
<h4><strong>Software</strong></h4>
<p>The Alltesta™ Autosampler can be controlled:</p>
<ul>
<li>directly via serial commands (Alltesta™ protocol available upon request, please contact us at support@sielc.com),</li>
<li>directly via our demo software, allowing to learn the whole functionality of the unit (<a href="https://sielc.com/wp-content/uploads/2022/12/Alltesta_Autosampler_Control_Windows_10.zip"><strong>Windows 10, 32/64bit</strong></a>, 5Mb; <a href="https://sielc.com/wp-content/uploads/2022/12/Alltesta_Autosampler_Control_Windows_7.zip"><strong>Windows 7, 32/64bit</strong></a>, 126Mb).</li>
<li>remotely through our cloud software (as a part of Alltesta™ Analyzer or Alltesta™ Mini Analyzer),</li>
</ul>
<p>Serial communication drivers are available <a href="https://ftdichip.com/drivers/vcp-drivers/"><strong>here</strong></a>.</p>


SIELC Alltesta™ Mini LHS (Liquid Handling Station)

The Alltesta™ Mini Liquid Handling Station serves as an affordable, reliable solution for automated sample handling.

<p><strong>The Alltesta™ Mini Liquid Handling Station serves as an affordable, reliable solution for automated sample handling. With its compact design, proprietary alpha/beta mechanical structure, and adjustable operation speeds, it offers comprehensive control for quick and seamless integration with other equipment. The station comes equipped with a built-in sample shaking feature for in-vial sample mixing and extraction, and a needle washing station capable of accommodating up to four solvents.</strong></p>
<p>Designed with Original Equipment Manufacturer (OEM) customization in mind, the Alltesta™ Mini Liquid Handling Station can be tailored to fit any system’s requirements. Custom needle lengths and trays enable the device to accommodate various types of vials. An array of integrated valves and a measuring syringe can be added to the device. Additional customization options, such as metal-free flow paths and customer-specified enclosure colors, are also available.</p>
<p>Comprehensive software integration support is provided to ensure smooth operation and functionality.</p>
<h4><strong>Specifications</strong></h4>
<ul>
<li>Dimensions (WHL): 160 x 145 x 195 mm / 6.3 x 5.71 x 7.68 in</li>
<li>Weight: 2.25 kg / 5 lb</li>
<li>Power: 24 V</li>
<li>Capacity: 48-vial tray or 96-well plate</li>
<li>Needle Wash: Inside and Outside</li>
<li>Communication: RS232 Virtual COM port via USB</li>
</ul>
<h4><strong>Software</strong></h4>
<p>The Alltesta™ LHS can be fully controlled via serial commands. Alltesta™ protocol available upon request, please contact us at support@sielc.com. Serial communication drivers are available <a href="https://ftdichip.com/drivers/vcp-drivers/"><strong>here</strong></a>.</p>


Watrex xTrovert FLEX-O automation SPE sample preparation system

FLEX-O robotic system enabling automation sample preparation on solid phase using 96-titre plates.

<p><strong>FLEX-O robotic system enabling automation sample preparation on solid phase using 96-titre plates. Although there are solutions for automatic SPE on classic column formats, robotic system for automation in 96-well SPE plates is not currently on the market.</strong></p><p>In addition to <strong>the 8-channel pipetting head</strong>, the robot is equipped with <strong>a gripper</strong> and <strong>a filling dispenser</strong>, which applies wash solutions to the SPE positions on the plate. Instead of filtering using classic vacuum pump, which is used for manual SPE on columns or 96plates, the <a target="_blank" rel="noopener noreferrer" href="https://watrex.com/obchod/laboratory-automation/xtrovert-flex-o/?utm_source=labrulez&amp;utm_medium=propagace&amp;utm_campaign=labrulez_produkty"><strong>xTrovert FLEX-O</strong></a> system uses the so-called <strong>positive pressure technology</strong> when it is the reagent is pushed through the SPE membrane with a multi-channel pressure attachment. That’s it ensuring <strong>flow uniformity and reproducibility</strong> between individual samples on the plate.</p><p>The robot is capable of <strong>processing up to 4 x 96-well sample plates</strong> (384 of total samples) using a protocol with <strong>up to 8 different washing and extraction reagents</strong>.The system is <strong>compatible with the Waters OligoWorks™ SPE Macroplate</strong> (96-well), <strong>Waters Oasis™ PRiME HLB</strong>, <strong>Macherey-Nagel™ SPE MULTI 96-Monoblock CHROMABOND™</strong> and other 96-plate format SPE systems.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Watrex_x_Trovert_FLEX_O_automation_SPE_sample_preparation_system_ec3768960e.jpg" alt="Watrex xTrovert FLEX-O automation SPE sample preparation system.jpg" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Watrex_x_Trovert_FLEX_O_automation_SPE_sample_preparation_system_ec3768960e.jpg 208w," sizes="100vw" width="1433" height="1075"></p><p>If necessary, the <strong>user can make modifications to the log</strong> using a simple scripting language and subsequent wireless upload to the device. Userthe interface for controlling the system is based on the integrated computer Raspberry Pi ® s 800×480 RGB LCD multi-touch touch screen and the possibility of remote wifi accessfrom an external device (e.g. mobile phone or tablet).</p><h4>Application</h4><ul><li><strong>Purification of oligonucleotide synthesis products</strong></li><li><strong>Organic Synthesis</strong></li><li><strong>Environmental Analysis</strong></li><li><strong>Medical diagnostics</strong></li><li><strong>Molecular biology and biochemistry</strong></li></ul><p>The entire system was designed and developed by Watrex Praha and is <strong>manufactured in the Czech Republic</strong> and promises a shift in the performance and efficiency of laboratory processes worldwide!</p>

SIELC Samplify Automated sampling system

Samplify Is a device which allows unattended sampling of a reaction mixture or bioprocess or continue in line flow by taking small amount of liquid from the monitoring mixture and collecting it in a vial or a 96 wells plate

<p><strong>Samplify™ Is a device which allows unattended sampling of a reaction mixture or bioprocess or continue in line flow by taking small amount of liquid from the monitoring mixture and collecting it in a vial or a 96 wells plate. It also allows to dilute the sample with assigned dilution ratio and can provide reaction quenching to preserve the sample state at time of sampling. It has two main components: an autosampler and a probe. The Samplify™ &nbsp;controlled and setup by a PC software.</strong></p><h3><strong>Description</strong></h3><p>It is a common task in the lab to <strong>periodically sample a reactor</strong> or a fermenter to <strong>obtain information about reaction kinetic, completion and have a tangible representation of intermediate states of a dynamic process</strong>. This usually done manually with pipettes or syringes, using stopwatch to measure time and requires to be in the lab during the entire process.</p><p><strong>With Samplify it can be done in automated mode.</strong> When an automated sampling process is used it increases accuracy, safety, and productivity. It reduces potential samples cross contamination, and exposure of the reaction mixture to oxygen or moisture, when anaerobic or moisture free conditions are required.</p><ul><li>Based on a proprietary alpha/beta mechanical configuration, <strong>Alltesta Miniature Autosampler</strong> and patent pending sample probe offers affordable and reliable <strong>automation</strong> <strong>for many analytical and liquid-handling applications</strong>.&nbsp;</li><li>Small <strong>controllable volume of sample</strong> can be programmed and precisely removed from the <strong>enclosed or open system</strong>. The sample will then be transferred to a vial with inert solvent with measured volume to create a <strong>controllable dilution factor</strong>.</li><li><strong>A quench solution can be automatically preloaded</strong> in each vial to provide termination of reaction or biological process, and preserve sample content in the time of probing.</li><li>In order to effectively mix samples with diluents or quenching reagents a <strong>shaking capability</strong> of the autosampler tray can be initiated after each sample cycle.</li><li><strong>PC based software</strong> allows quick, but flexible, setup of the sampling experiment. Several <strong>preloaded methods</strong> can be quickly adapted to a particular needs of the user.</li><li>For temperature sensitive samples the entire autosampler can be placed in the <strong>temperature controlled</strong> environment.</li><li>The device <strong>small size</strong> allow to place it close to the reactor and use <strong>short connection lines</strong> to minimize dispersion. Also a small cooler can be used to keep samples in cold conditions after they are collected.</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/SIELC_SIELC_Samplify_Automated_sampling_system_937b70e8d2.jpg" alt="SIELC: SIELC Samplify™ Automated sampling system." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_SIELC_SIELC_Samplify_Automated_sampling_system_937b70e8d2.jpg 245w," sizes="100vw" width="1346" height="663"></p><h3><strong>Specifications</strong></h3><h4><strong>Samplify™ Autosampler:</strong></h4><ul><li><strong>Syringe volume: </strong>4.0 mL</li><li><strong>Pressure: </strong>up to 250 psi</li><li><strong>Valve configuration: </strong>7×6</li><li><strong>Power Requirements:</strong> 24 VDC</li><li><strong>Current Requirements:</strong> Up to 1.0 A</li><li><strong>Dimensions (WHL):</strong> 160 x 145 x 195 mm / 6.3 x 5.71 x 7.68 in</li><li><strong>Weight:</strong> &nbsp;3 kg / 6.6 lb</li><li><strong>Inlets/Outlets:</strong> Thread 10-32 UNF compression type</li><li><strong>Materials in contact with liquid:</strong> SS316, PTFE, PEEK</li><li><strong>Tray capacity: </strong>48 vials 1.8 mL volume or 96 wells plate</li><li><strong>Communication:</strong> USB virtual serial port</li></ul><h4><strong>Samplify™ Probe:</strong></h4><ul><li><strong>Connection</strong>: requires Alltesta-Samplify autosampler</li><li><strong>Dimensions:</strong> 1 x 1 inch, DIA ¼ inch. Immersion length up to 6 inch</li><li><strong>Materials in contact with liquid: </strong>Stainless Steel 316 (316L), PEEK &amp; PTFE</li><li><strong>Variable sample volume: </strong>from 5 to 500 µL</li><li><strong>Max. working pressure:</strong> 120 psi (8 bar)</li><li><strong>Max. working temperature:</strong> &nbsp;200 °C</li></ul><h3><strong>Software</strong></h3><p><strong>The Samplify can be controlled:</strong></p><ul><li><strong>directly through your software via serial commands</strong> (Alltesta™ protocol available upon request, please contact us at support@sielc.com),</li><li><strong>remotely through our cloud so</strong>ftware (autosampler.cloud),</li><li><strong>directly via our Samplify PC software</strong>, allowing to fully control all the parameters of the sampling operations</li></ul><h3><strong>Available Custom Options</strong></h3><p>Metal-free version of the syringe pump includes no metal contact pump head.</p>

Waters Andrew+ pipetting robot

Andrew+ pipetting robot offers fully automated liquid handling using electronic pipettes and labware holders called Dominos.

<div data-id="7b8f701" data-element_type="widget" data-widget_type="heading.default"><div><h3><strong>Discover lab automation within reach</strong></h3></div></div><div data-id="c1b56fb" data-element_type="widget" data-widget_type="text-editor.default"><div><p><strong>Andrew+ pipetting robot offers fully automated liquid handling using electronic pipettes and labware holders called Dominos. By adding Device+, our ever-expanding portfolio of connected devices and tools for processes such as heating, shaking or labware transportation, Andrew+ evolves into a full walk-away automation solution.</strong></p><p>Creating the connected laboratory, Andrew+ is part of the&nbsp;<a target="_blank" rel="noopener noreferrer" href="https://www.andrewalliance.com/laboratory-software/"><strong>OneLab</strong></a>&nbsp;ecosystem, executing laboratory protocols designed in OneLab.&nbsp; This flexible architecture enables you to effortlessly transition from laborious manual pipetting procedures to error-free, fully-robotized lab workflows – without any knowledge of programming, laboratory robotics or automation engineering.</p><blockquote><p class="cke-user_style-important"><strong>Video: </strong><a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/watch?v=IGu3YxkkZY0"><strong>Andrew+ Demo</strong></a></p></blockquote><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Andrew_pipetting_robot_4_0569f8609e.jpg" alt="Waters Andrew+ pipetting robot" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Andrew_pipetting_robot_4_0569f8609e.jpg 245w," sizes="100vw" width="1440" height="540"></p><h3><strong>Andrew+ Case Studies&nbsp;</strong></h3><blockquote><p class="cke-user_style-important"><a target="_blank" rel="noopener noreferrer" href="https://www.andrewalliance.com/category/case-studies/"><span>See all case studies</span>&nbsp;</a></p></blockquote><div data-id="ee37b9e" data-element_type="widget" data-widget_type="heading.default"><div><h3><strong>Watch Andrew+ in action</strong></h3></div></div><div data-id="b265a33" data-element_type="widget" data-widget_type="text-editor.default"><div><p>In these videos, our biologists explain how Andrew+ enables users to automate commonly used, laborious, liquid handling for PCR Prep and Plasmid DNA Purification, respectively, whilst ensuring superior repeatability and full traceability.</p><blockquote><p class="cke-user_style-important"><strong>Video: </strong><a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/watch?v=RnxDri3Z7f4"><strong>PCR Prep</strong></a></p><p class="cke-user_style-important"><strong>Video: </strong><a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/watch?v=oWOkzqF9X9I"><strong>Plasmid DNA Prep</strong></a></p></blockquote><div data-id="fc9cb9e" data-element_type="column"><div><div data-id="cbb1a9b" data-element_type="widget" data-widget_type="heading.default"><div><h3><strong>Intuitive user interface</strong></h3></div></div><div data-id="3799119" data-element_type="widget" data-widget_type="text-editor.default"><div><div><div><div><div><div><p>Reproducibility and full traceability of sample preparation is assured using a highly intuitive browser-based software environment.&nbsp;<a target="_blank" rel="noopener noreferrer" href="https://www.andrewalliance.com/laboratory-software/"><strong>OneLab</strong></a> enables scientists to graphically design their own pipetting protocols in minutes and execute them straight away in any laboratory in the world, even allowing the remote monitoring of ongoing experiments. Use a flexible and secure platform that withstands the rigors of regulatory validation.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Onelab_design_2_489d32ac68/Waters-Onelab-design-2_l.webp" alt="Waters-Onelab-design-2_l.webp" width="1027" height="488"></p><div data-id="9199ea6" data-element_type="column"><div><div data-id="6db85f8" data-element_type="widget" data-widget_type="heading.default"><div><h3><strong>Widest pipetting volume range</strong></h3></div></div><div data-id="ae0caea" data-element_type="widget" data-widget_type="text-editor.default"><div><p>Andrew+ pipetting robot uses single and multichannel electronic pipettes, ensuring the best liquid handling performance and maximum flexibility. Smart electronic pipettes are manufactured by Sartorius and based upon their acclaimed Picus pipettes.</p><p>Electronic pipettes are optimized for used with the Andrew+ pipetting robot, allowing greater flexibility in the type of liquid handling experiments that can be run, providing superior experiment reproducibility, pipetting speed and a market leading dynamic range of dispensing volumes for a liquid handing robot –from 0.2 µL up to 10 mL.</p><figure class="image"><img style="aspect-ratio:529/382;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Andrew_pipetting_robot_f5ca4f825d.jpg" alt="Waters Andrew+ pipetting robot.jpg" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Andrew_pipetting_robot_f5ca4f825d.jpg 216w," sizes="100vw" width="529" height="382"></figure><div data-id="ed235f6" data-element_type="column"><div><div data-id="ef6b933" data-element_type="widget" data-widget_type="heading.default"><div><h3><strong>Andrew+ is compact</strong></h3></div></div><div data-id="7537e2e" data-element_type="widget" data-widget_type="text-editor.default"><div><div><div><div><div><div><p>The liquid handling robot is designed to fit the majority of laboratory benches and biosafety cabinets (BSC). Andrew+, even with 2 full rows of Dominos&nbsp;<i>(</i>allowing to use 7 microplates or 56 falcon tubes or 168 microtubes) occupies a depth of ~55cm/22”, that fits even the smallest hoods. The unique compact size and design of our liquid handler allows it to work at a temperature of 20°C-37°C.&nbsp;</p><figure class="image"><img style="aspect-ratio:836/556;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Andrew_pipetting_robot_2_fb174b1453.jpg" alt="Waters Andrew+ pipetting robot - 2.jpg" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Andrew_pipetting_robot_2_fb174b1453.jpg 235w," sizes="100vw" width="836" height="556"></figure><div data-id="c9b37a7" data-element_type="widget" data-widget_type="heading.default"><div><h3><strong>Versatile working deck, tools and devices for all your needs</strong></h3></div></div><section data-id="b802f90" data-element_type="section" data-settings="{&quot;jet_parallax_layout_list&quot;:[]}"><div><div data-id="3e689f0" data-element_type="column"><div><div data-id="5dc9372" data-element_type="widget" data-widget_type="text-editor.default"><div><p>The Andrew+ deck layout is quickly adaptable to your experiment materials and are incredibly easy to set with the ever-expanding range of Dominos: a magnetic-based modular solution that enables Andrew+ to use a broad range of consumables.</p></div></div></div></div><div data-id="5626074" data-element_type="column"><div><div data-id="40c6ef1" data-element_type="widget" data-widget_type="text-editor.default"><div><p>In addition to pipetting liquids, the Andrew+ liquid handler can perform a wide range of complex experimental steps such as tube/plate transport or solid-phase extraction using vacuum.<br>Thanks to OneLab, you will benefit to a seamless integration of new capabilities added to your setting.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Andrew_pipetting_robot_3_89b87a0d2e.jpg" alt="Waters Andrew+ pipetting robot - 3.jpg" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Andrew_pipetting_robot_3_89b87a0d2e.jpg 245w," sizes="100vw" width="1734" height="598"></p><div data-id="d090821" data-element_type="column"><div><div data-id="f9d733b" data-element_type="widget" data-widget_type="heading.default"><div><h3><strong>Automated Protocols with Andrew+</strong></h3><p>Specifically optimized for Andrew+, various applications and methods guarantee the delivery of better pipetting accuracy and improved reproducibility.</p><blockquote><ul><li><div><a target="_blank" rel="noopener noreferrer" href="https://onelab.andrewalliance.com/library/sars-cov-2-lc-ms-kit-ruo-9lwrvwkA"><span>Automated preparation of SARS-CoV-2 peptides for LC-MS analysis</span></a></div></li><li><div><a target="_blank" rel="noopener noreferrer" href="https://onelab.andrewalliance.com/library/automated-antibody-purification-jlwKQ0aY"><span>Automated Antibody Purification for higher recovery and reproducibility</span></a></div></li><li><div><a target="_blank" rel="noopener noreferrer" href="https://onelab.andrewalliance.com/app/lab/bl6MQP6z/library/standard-curve-generation-KlwRbwR3"><span>Reliable and Robust Sample Prep for Standard Curve Generation</span></a></div></li></ul><p class="cke-user_style-important"><a target="_blank" rel="noopener noreferrer" href="https://onelab.andrewalliance.com/library"><span><strong>More to discover in the Protocol Library</strong></span></a></p></blockquote><h3><strong>Get an extra pair of hands</strong></h3><div data-id="aa4715f" data-element_type="widget" data-widget_type="heading.default"><div><h4><strong>Reproducibility</strong></h4></div></div><div data-id="a1d2f3b" data-element_type="widget" data-widget_type="text-editor.default"><div><div><div data-animationtype="fadeInDown" data-animationduration="0.7" data-animationoffset="top-into-view"><div><p>Laboratory automation eliminates most human errors resulting in more reliable data and improved productivity. Together with complete integration inside OneLab, all experimental data from Andrew+ will be recorded and stored, improving the traceability of experiments and the data analysis.</p><div data-id="fb36639" data-element_type="widget" data-widget_type="heading.default"><div><h4><strong>Productivity</strong></h4></div></div><div data-id="c5f6abd" data-element_type="widget" data-widget_type="text-editor.default"><div><div><div data-animationtype="fadeInDown" data-animationduration="0.7" data-animationoffset="top-into-view"><div><div><div data-animationtype="fadeInDown" data-animationduration="0.7" data-animationoffset="top-into-view"><div><p>Andrew+ combines the flexibility of single channel pipetting (0.2 μL to 10 mL) with the higher throughput of multichannel pipetting. In addition, Andrew+ reduces the need to repeat experiments due to pipetting errors.</p><div data-id="0a035d7" data-element_type="widget" data-widget_type="heading.default"><div><h4><strong>Promoting health</strong></h4></div></div><div data-id="a72e364" data-element_type="widget" data-widget_type="text-editor.default"><div><div><div data-animationtype="fadeInDown" data-animationduration="0.7" data-animationoffset="top-into-view"><div><div id="applications"><div><div><div><div><div id="icon-area" data-animationoffset="top-into-view"><div><div data-animationtype="fadeInDown" data-animationduration="0.7" data-animationoffset="top-into-view"><div><p>Pipetting requires repetitive movements (of up to 500 times per day for the average user) that can lead to musculo-skeletal disorders like repetitive strain injury. Andrew+ helps eliminates physical stress to professionals, and also reduces the risk of exposure to hazardous materials used in certain experimental procedures.</p></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></section></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div>

Watrex Streamline FC1 Fraction Collector

The fully automated fraction collector FC1 offers a universal solution for a number of applications requiring the collection of fractions, e.g. protein purification, preparative chromatography.

<p><strong>The fully automated fraction collector FC1 offers a universal solution for a number of applications requiring the collection of fractions, e.g. protein purification, preparative chromatography or other methods for obtaining samples by fractionation.</strong></p><blockquote><p><span style="font-size:18px;"><strong>Price: 4 260</strong><bdi><span class="wmc-cache-pid woocommerce-Price-amount amount" data-wmc_product_id="24487"><strong>&nbsp;</strong></span><span class="wmc-cache-pid woocommerce-Price-amount amount woocommerce-Price-currencySymbol" data-wmc_product_id="24487"><strong>€ ex VAT</strong></span></bdi></span></p></blockquote><p>For advanced programming and connection to chromatography software, the device is equipped with a <strong>USB interface</strong>. FC1 is supported by the <a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/products/305"><strong>Clarity Chromatography Station</strong></a></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Watrex_schema_procesu_sberu_frakci_pomoci_frakcni_kolektor_FC_1_fa579d59f2/Watrex-schema-procesu-sberu-frakci-pomoci-frakcni-kolektor-FC1.png" alt="Watrex: Schematic of the fraction collection process using the FC1 fraction collector"></p><p>The <strong>robust</strong> design of the FC1 ensures reliable X-Y displacement that carries the switching valve. Placing the fraction switch directly above the receiving vessel <strong>minimizes dead volume between fractions</strong>.</p><p>Depending on the <strong>required volume of fractions</strong>, different types of test tube stands are offered with the device. Furthermore, it is also possible to use large-volume containers.</p><p>The operator controls and programs the fraction collector from the <strong>touch screen</strong> on the front panel of the device using intuitively arranged screens with adjustable parameters for a given fraction collection series.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Watrex_Nastaveni_treshold_limitu_pro_sber_frakci_pomoci_sberace_frakci_FC_1_f48d645dfc/Watrex-Nastaveni-treshold-limitu-pro-sber-frakci-pomoci-sberace-frakci-FC1.jpg" alt="Watrex: Setting the treshold limit for fraction collection using the FC1 fraction collector"></p><h3><strong>FEATURES</strong></h3><ul><li>Simple operation</li><li>Color touch panel control</li><li>Optional analog input</li><li>Selection of rack types</li><li>Clarity CDS supported</li></ul><h3><strong>TECHNICAL SPECIFICATION</strong></h3><ul><li><strong>Max. flow:</strong> 50 ml/min</li><li><strong>Wetted Materials:</strong> PTFE, PEEK</li><li><strong>User control:</strong> Color touch panel</li><li><strong>PC connection:</strong> USB</li><li><strong>External control:</strong> TTL (contact closure) - RUN, STOP, NEXT, COLLECT</li><li><strong>Power supply:</strong> 24V DC external power supply</li></ul><h3><strong>Ordering information:</strong></h3><h5><strong>PN/Component:</strong></h5><ul><li><strong>SFC101-001</strong> Streamline™ FC1 Fraction Collector</li><li><strong>SFC101-002</strong> Cooling option for FC1 Fraction Collector</li><li><strong>SFC101-003</strong> Analog Signal Monitoring, Input for FC1 Fraction Collector</li></ul><p><strong>You can also visit this product on the </strong><a target="_blank" rel="noopener noreferrer" href="https://watrex.com/obchod/chromatography/dedicated-instruments/streamline-fc1-fraction-collector/?utm_source=labrulez&amp;utm_medium=propagace&amp;utm_campaign=labrulez_produkty"><strong>Watrex website</strong></a><strong>.</strong></p>

Thermo Scientific Dionex AutoTrace 280 Solid-Phase Extraction Instrument

Extract analytes of interest from large volume aqueous samples easily and efficiently with the Thermo Scientific™ Dionex™ AutoTrace™ 280 Solid-Phase Extraction (SPE) Instrument.

<p><strong>Extract analytes of interest from large volume aqueous samples easily and efficiently with the Thermo Scientific™ Dionex™ AutoTrace™ 280 Solid-Phase Extraction (SPE) Instrument.&nbsp;</strong></p><p>The AutoTrace 280 automates all four steps of SPE (conditioning, loading, rinsing, and eluting), reducing solvent consumption and improving recovery and reproducibility. Boost productivity and reduce cost of analysis by simultaneously processing up to six samples in 2-3 hours with only 15 minutes of operator involvement. The AutoTrace 280 meets requirements in US EPA methods including the 500 and 600 series.</p><h5><strong>Improved reliability and recovery</strong></h5><ul><li>Automated SPE minimizes operator intervention</li><li>Positive pressure loading and elution of samples and solvents provide constant flow for improved analytical precision</li></ul><h5><strong>Flexibility in operation</strong></h5><ul><li>Loads sample volumes from 20 mL to 4 L</li><li>Compatible with 1, 3, and 6 mL cartridges and with 47 mm SPE disks</li><li>Automatically conditions, rinses, and elutes SPE cartridges with a choice of five solvents</li><li>Offers a choice of six different collection vial racks</li></ul><h5><strong>Improved laboratory safety</strong></h5><ul><li>Minimal sample handling reduces operator exposure to hazardous chemicals</li><li>No hood required</li></ul><h5><strong>Enhanced laboratory productivity and reduced costs</strong></h5><ul><li>Unattended operation</li><li>Batch processing of up to 6 samples</li><li>Reduced solvent usage</li><li>Segregates aqueous and solvent waste using separate waste lines for efficient, cost-effective waste handling</li></ul><h5><strong>Supports a range of matrices and applications</strong></h5><ul><li>Ability to process samples containing suspended solids</li><li>Meets requirements for solid-phase extraction for U.S. EPA methods including 500 and 600 series</li></ul><h5><strong>Recommended use</strong></h5><ul><li>Analyze prepared samples with Thermo Scientific LC or GC systems for a fully integrated workflow</li></ul><h4><strong>Specifications</strong></h4><ul><li><strong>Instrument Type:</strong> Automated Solid Phase Extraction (SPE) System</li><li><strong>Application:</strong> For use with 47 mm SPE disks</li><li><strong>Model Description:</strong> AutoTrace 280 SPE System</li></ul><h5><strong>Performance &amp; Operating Details</strong></h5><ul><li><strong>Disk Compatibility:</strong> Designed for 47 mm SPE disks</li><li><strong>Pressure Range:</strong><ul><li>Output: 0 to 30 psi (0 to 1.4 bar)</li><li>Input: Up to 100 psi (6.9 bar) maximum</li></ul></li><li><strong>Voltage:</strong> 100–240 V ±10%</li><li><strong>Frequency:</strong> 47–63 Hz</li></ul><h5><strong>Physical Specifications</strong></h5><ul><li><strong>Dimensions (D × W × H):</strong> 57 × 63.5 × 69 cm</li><li><strong>Unit Size:</strong> Each</li></ul>

Thermo Scientific EXTREVA ASE Accelerated Solvent Extractor

Achieve true walkaway sample-to-vial sample preparation with the Thermo Scientific™ EXTREVA™ ASE™ Accelerated Solvent Extractor. 

<p><strong>Achieve true walkaway sample-to-vial sample preparation with the Thermo Scientific™ EXTREVA™ ASE™ Accelerated Solvent Extractor. Without any intervention, perform sample extraction, in-cell cleanup and evaporation—all in one seamless operation—reducing manual labor from hours to minutes and enabling you to focus on other lab priorities while using up to 50% less solvent than other sample preparation techniques.</strong></p><p><strong>Accelerate your journey from sample to vial</strong></p><h5><strong>The EXTREVA ASE Accelerated Solvent Extractor offers:</strong></h5><ul><li><strong>All-in-one sample preparation.</strong> The EXTREVA ASE system automatically extracts and concentrates samples, eliminating the need to manually move sample extracts to another device for solvent evaporation.</li><li><strong>A walk-away solution. </strong>The system minimizes hands-on sample preparation tasks, enabling staff to accomplish other tasks.</li><li><strong>Parallel extraction. </strong>One EXTREVA ASE system can perform four parallel sample extractions, substantially increasing throughput.</li><li><strong>Gas-assisted extraction. </strong>The dynamic gas-assisted extraction mode reduces solvent consumption to between 5 and 100 milliliters per sample in most cases.</li><li><strong>Automation. </strong>Full automation improves recoveries and reproducibility while reducing training needs. Unlike humans, automated systems are ideal for performing the same tedious task repeatedly, and they don’t make mistakes.</li><li><strong>Method flexibility and optimization</strong>. Up to six different solvents can be used, including wash solvents for cleaning between methods. Precise flow control optimizes methods.</li><li><strong>Barcode-reading.</strong> The system tracks sample information and preparation parameters using a 2-D bar code reader to facilitate tracking and integrity. Data is recorded on the instrument or Thermo Scientific™ <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/76"><strong>Chromeleon™ Chromatography Data System (CDS) software</strong></a>.</li></ul><h4><strong>Specifications</strong></h4><ul><li><strong>Instrument Type:</strong> Automated Sample Preparation System</li><li><strong>Application:</strong> Simultaneous sample extraction and concentration</li><li><strong>Model Description:</strong> EXTREVA ASE Extraction and Evaporation System</li></ul><h5><strong>Performance &amp; Capabilities</strong></h5><ul><li><strong>Extraction Temperature Range:</strong> 40–200 °C</li><li><strong>Evaporation Temperature Range:</strong> 40–100 °C</li><li><strong>Compatible Solvents:</strong> Wide range of organic and aqueous solvents</li><li><strong>Pressure Capability:</strong> Up to 200 psi</li><li><strong>Power Consumption:</strong> 2000 W</li><li><strong>Frequency:</strong> 50/60 Hz</li></ul><h5><strong>Sample &amp; Solvent Handling</strong></h5><ul><li><strong>Extraction Cells (stainless steel):</strong> 1, 5, 10, 22, 34, 66, 100 mL</li><li><strong>Extraction Cell Tray:</strong> 16-position with 1 rinse</li><li><strong>Collection Vials:</strong><ul><li>60 mL and 100 mL evaporation vials</li><li>250 mL evaporation bottles</li><li>Direct concentrate to 2 mL sample vials with rinse capability</li></ul></li><li><strong>Collection Vial Tray:</strong> 16-position tray insert for 60 mL vials and 250 mL bottles; includes 4 rinse positions</li></ul><h5><strong>Utilities &amp; Requirements</strong></h5><ul><li><strong>Pneumatic Requirements:</strong><ul><li>Air: 130–140 psi</li><li>Nitrogen: 350–450 psi</li></ul></li></ul><h5><strong>Physical Specifications</strong></h5><ul><li><strong>Dimensions (D × W × H):</strong> 65.2 × 100 × 88.6 cm (25.6 × 39.4 × 34.8 in.)</li><li><strong>Weight:</strong> 160 kg (353 lb)</li><li><strong>Unit Size:</strong> Each</li></ul>

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