Phenomenex Luna Omega HILIC HPLC Columns

Luna Omega HILIC columns combine thermally modified fully porous particles with a bonded diol stationary phase to provide enhanced retention and selectivity for polar analytes under HILIC conditions. Designed for small polar molecules, metabolites, nucleobases, pharmaceuticals, and other challenging compounds, these columns deliver excellent chromatographic performance and robustness.

The diol stationary phase provides multiple interaction mechanisms that improve retention and separation of polar compounds while maintaining excellent peak shape and reproducibility. The thermally modified fully porous particles extend column lifetime and ensure reliable performance across demanding analytical workflows.

Technical Specifications

Stationary Phase

• Phase: Diol
• USP Classification: L20

Particle Characteristics

• Particle Sizes:
  • 1.6 µm
  • 3 µm
• Pore Size: 100 Å
• Surface Area: 260 m²/g
• Carbon Load: 5 %

Chemical Properties

• pH Range: 2.0–7.0
• Maximum Pressure: 1034 bar (15,000 psi)

Available Dimensions

• Lengths:
  • 50 mm
  • 100 mm
  • 150 mm
  • 250 mm
• Internal Diameters:
  • 2.1 mm
  • 3.0 mm
  • 4.6 mm

Typical Applications

• HILIC separations
• Nucleobases
• Nucleotides
• Metabolomics
• Pharmaceutical analysis
• Bioanalytical workflows
• Food analysis
• Environmental testing

Phenomenex: Separation of Nucleobases with Luna Omega 3μm HILIC. 1. Thymine 2. Uracil 3. Adenine 4. Cytosine 5. Guanine

Phenomenex Luna Omega HPLC/UHPLC Columns

The cutting edge thermally modified Luna Omega particle delivers high efficiency, ruggedness, reproducibility, and dependability for a wide range of chromatographic analyses. Luna Omega HPLC and UHPLC columns are built upon more then 20 years of applied knowledge, invention, and customer experience in the manufacture and packing of LC columns. The particle’s novel design and proprietary manufacturing process results in greater particle inertness, a stronger particle morphology, and more consistent porosity.

• Greater separation muscle and retention
• Consistent porous structure and elimination of micropores
• Extreme ruggedness and reproducibility

Phenomenex:Thermal modified pore structure of Luna Omega Column particles

Explore Luna Omega Columns

Astounding Performance

The undeniably high efficiency levels found in each Luna Omega UHPLC column provide you with the potential of huge gains in method performance. While traditional silica and hybrid fully porous particles claim high performance, when compared to Luna Omega 1.6 μm, they drastically fall short and prevent UHPLC scientists from reaching their UHPLC potential.

Separation Muscle

Our industry leading bonding technologies in conjunction with high efficiency levels ensure excellent stationary phase coverage and improved separation power. Now, with Luna Omega 1.6 μm, you can turn difficult separations into resolution achievements.

Inert Foundation

Luna Omega UHPLC columns contain a unique silica modified using a proprietary, post-synthetic thermal treatment process to provide extraordinary mechanical strength and significantly greater inertness than traditional fully porous and hybrid materials. This greatly minimizes secondary interactions that negatively affect peak shape, allowing for greater method accuracy.

Consistent Results

Batch-to-batch and column-to-column, Luna® Omega media and columns are designed to be consistent and incredibly accurate tools for your analysis. Each batch and column are quality tested to ensure dependability and reproducibility.