<h3><a target="_blank" rel="noopener noreferrer" href="https://www.isc2026.org/"><strong>ISC 2026</strong></a></h3><p><strong>The </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/314"><strong>International Symposium on Chromatography (ISC)</strong></a><strong> represents the oldest conference series on separation science. ISC symposia have been organised since 1956 in each even year. ISC is one of the premier meetings series for discussion of all modes of chromatography and separation science with a broad coverage of techniques and applications.</strong></p><p>The major focus of the symposium will be on the impact of chromatography and separation science to meet the needs of the pharmaceutical, environmental, food and health industry, as well as science and medicine. The symposium programme will reflect these themes and highlight new challenges and emerging opportunities for the science and marketing of separation and detection systems and methods.</p><p>As an integral part of the scientific programme of lectures and poster sessions, an international exhibition and vendor seminars on instrumentation and services for chromatography, separation science and mass spectrometry will be organised. ISC 2026 will provide the perfect forum for attendees from academia, industry and government research institutions for scientific exchange and networking.</p><h3><strong>REGISTRATION</strong></h3><blockquote><p class="cke-user_style-important"><strong>👉</strong><a target="_blank" rel="noopener noreferrer" href="https://www.czech-in.org/cmPortalV15/Account/Login?ReturnUrl=%2FcmPortalV15%2FPortal%2FISC26%2Fnormal"><strong>Register NOW and do not miss the deadline</strong></a></p><ul><li><strong>Early-bird registration &amp; payment deadline:</strong> May 15, 2026</li><li><strong>Payment deadline for authors of oral presentations: </strong>May 15, 2026</li></ul></blockquote><h3><strong>TUTORIAL LECTURES</strong></h3><h5><strong>Bezhan Chankvetadze</strong></h5><p>Bezhan Chankvetadze is Professor for Physical Chemistry and director of the Institute of Physical and Analytical Chemistry at the Tbilisi State University in Tbilisi, Georgia.</p><p>He is the Editor-in-Chief of the Journal of Pharmaceutical and Biomedical Analysis and a member of the editorial boards several international journals.</p><p>Chankvetadze is the recipient of “2006 Belgian Society of Pharmaceutical Science Award of Recognition”, the joint Csaba Horvath Memorial Award of the Hungarian Separation Science Society and Connecticut Separation Science Council, USA (2017) and Nernst-Tswett Award from the European Separation Science Society (EuSSS) (2024).</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ISC_Bezhan_Chankvetadze_b97143b6b0.jpg" alt="ISC 2026: Bezhan Chankvetadze" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ISC_Bezhan_Chankvetadze_b97143b6b0.jpg 156w," sizes="100vw" width="480" height="480"></p><h5><strong>Martin Gilar</strong></h5><p>Dr. Martin Gilar received his Ph.D. in analytical chemistry from Institute of Chemical Technology in Prague (1996). He spent postdoc years in Hybridon Inc. (1996-1998) and Northeastern University in Boston (1998) developing separation methods for antisense oligonucleotides and fraction collector for DNA molecules. Since 1998 he has worked at Waters Corp. in Milford, Massachusetts, participating in column, sample preparation and instrument research.</p><p>Dr. Martin Gilar is a Research Fellow in the Separations R&amp;D group at <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/325"><strong>Waters Corporation</strong></a>. He has 30+ years of experience in the separation sciences, including chromatography, electrophoresis, and mass spectrometry. His research interest is the analysis of biopolymers, peptides, and nucleic acids. He has published over 75 peer reviewed papers. Dr. Gilar is recipient of Jaroslav Janak 2022 medal and Chromatographic Society Jubilee medal in 2023.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ISC_Martin_Gilar_3545a57ff2.jpg" alt="ISC 2026: Martin Gilar" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ISC_Martin_Gilar_3545a57ff2.jpg 156w," sizes="100vw" width="480" height="480"></p><h5><strong>Václav Kašička</strong></h5><p>Václav Kašička is head of Laboratory of Electromigration Methods (www.uochb.cz/kasicka) at the <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/62"><strong>Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences</strong></a> since 1995. He is engaged in development of electroseparation methods and their application for analysis and characterization of (bio)molecules. He is (co)author of 200 papers in impacted journals, 20 book chapters, and 160 lectures at international symposia, with 4922 citations, h-index 39. He is associated editor of the Journal of Separation Science, and member of editorial boards of Electrophoresis, J. Chromatogr. A and other journals. He is chair of Chromatography and Electrophoresis Group of the Czech Chemical Society, and member of permanent Scientific Committees of International Symposia ITP YYYY and LACE YYYY.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ISC_Vaclav_Kasicka_520987cd65.jpg" alt="ISC 2026: Václav Kašička" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ISC_Vaclav_Kasicka_520987cd65.jpg 156w," sizes="100vw" width="480" height="480"></p><h5><strong>Jörg P. Kutter</strong></h5><p>Professor Dr. Jörg P. Kutter holds a B.Sc. and a Ph.D. in analytical chemistry (1995) from the University of Ulm, Germany, focusing on chromatographic and electrophoretic techniques.</p><p>After graduation, he was a postdoctoral fellow at Oak Ridge National Laboratory (Oak Ridge, TN, USA) developing microchip-based analytical tools. He joined the Technical University of Denmark (DTU) in 1998, and in 2006, he was appointed professor in experimental lab-on-a-chip systems.</p><p>Since September 2013, Dr. Kutter is the Chair of Analytical Biosciences at the Dept. of Pharmacy at the University of Copenhagen. His research interests focus on the development of miniaturized separation and sample preparation methods.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ISC_Joerg_P_Kutter_15b28eb930.jpg" alt="ISC 2026: Jörg P. Kutter" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ISC_Joerg_P_Kutter_15b28eb930.jpg 156w," sizes="100vw" width="480" height="480"></p><h5><strong>John A. McLean</strong></h5><p>John A. McLean is Dean of Research Graduate Education, Stevenson Professor of Chemistry, and Director of the Center for Innovative Technologies at Vanderbilt University. McLean and colleagues have focused on the conceptualization, design, and construction of ion mobility and structural mass spectrometers, specifically targeting complex samples in systems, synthetic, and chemical biology. His group applies these strategies to forefront translational research areas in drug discovery, personalized medicine, and ‘human-on-chip’ synthetic biology platforms. He is an elected Fellow of NAI, AAAS, RCS, and ASMS and has published over 200 manuscripts and received over 30 patents in these and allied areas.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ISC_John_A_Mc_Lean_62fe6879ae.jpg" alt="ISC 2026: John A. McLean" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ISC_John_A_Mc_Lean_62fe6879ae.jpg 156w," sizes="100vw" width="480" height="480"></p><h5><strong>Peter Schoenmakers</strong></h5><p>Peter Schoenmakers has been a full-time professor in Analytical Chemistry at the University of Amsterdam since 2002, investigating many aspects of one- and two-dimensional chromatography, with a special interest in macromolecules and computer-assisted method development.</p><p>Together with Bob Pirok, Peter Schoenmakers has recently completed a new textbook on Analytical Separation Science. He has received a number of international awards, most recently the ACS Award for Chromatography (2022) and the LCGC lifetime-achievement award (2023). He received royal recognition when he became Knight in the Order of the Dutch Lion in 2022.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ISC_Peter_Schoenmakers_6962648388.jpg" alt="ISC 2026: Peter Schoenmakers" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ISC_Peter_Schoenmakers_6962648388.jpg 156w," sizes="100vw" width="185" height="185"></p><h5><strong>František Švec</strong></h5><p>Frantisek Svec is working at the Faculty of Pharmacy at Charles University in Hradec Kralove, Czech Republic. He has authored over 560 publications, which have been cited more than 25,000 times, giving him an h-index of around 100. F. Svec is best known for his research on monoliths and their use in many different applications. Currently, he is focusing on developing novel formats of sorbents for sample preparation.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ISC_Frantisek_Svec_9413f4a131.jpg" alt="ISC 2026: František Švec" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ISC_Frantisek_Svec_9413f4a131.jpg 156w," sizes="100vw" width="480" height="480"></p>

Tutorial Lectures at ISC 2026

<p><strong>Don't miss this unique opportunity to stand out at the upcoming HTC-19 conference by winning the HTC Tube competition! Deadline for submissions is coming up soon on Friday 15 May! The winners get 750 Euro (first prize), 500 Euro (second prize) and 250 Euro (third prize). That's a lot of Belgian Beer!</strong></p><h4><strong>Criteria for evaluation</strong></h4><ul><li>We invite scientists to create <strong>short videos (up to 3 minutes) </strong>that showcase how your chromatography work impacts the world.&nbsp;</li><li>No need for professional editing, just grab your smartphone and start filming.&nbsp;</li><li>Best video will be selected via electronic audience poll, based on scientific content, entertainment value, creativity and technical skills.</li></ul><h4><strong>Who can participate?</strong></h4><ul><li><strong>Eligibility: </strong>Scientists (academic or industrial) of any age involved in research projects related to the liquid chromatography workflow (before, during, or after).</li><li><strong>Submissions:</strong> Both individual and group submissions are welcome. The video must be based on the presenter’s own findings or work.</li></ul><h4><strong>Deadline and how to submit?</strong></h4><ul><li><strong>Deadline: Friday 15 May 2026</strong></li><li>Please send your submission to <strong>info@htc-19.com</strong></li></ul>

HTC Tube Competition at the 19th International Symposium on Hyphenated Techniques in Chromatography and Separation Technology (HTC-19)

<h4><strong>Advancing Glycoproteomics with Flexible LC-MS at the University of Washington</strong></h4><p><strong>Understanding how cells communicate, migrate, and interact with the immune system often comes down to what is happening on their surface. For Nick Riley, Assistant Professor at the University of Washington, that surface is defined by glycans, complex sugar structures attached to proteins that play a critical role in health and disease.</strong></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_What_Happens_When_Glycoproteomics_Meets_Real_Time_LC_MS_Decision_Making_7f77f81741.jpeg" alt="Thermo Fisher Scientific: What Happens When Glycoproteomics Meets Real-Time LC-MS Decision Making?: Nick Riley, Assistant Professor Department of Chemistry, University of Washington, head of the Riley Group." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_What_Happens_When_Glycoproteomics_Meets_Real_Time_LC_MS_Decision_Making_7f77f81741.jpeg 208w," sizes="100vw" width="1024" height="768"></p><p>The<strong> </strong><a target="_blank" rel="noopener noreferrer" href="https://www.riley-research.com/"><strong>Riley Group</strong></a> operates at the intersection of glycobiology and mass spectrometry, developing new analytical methods to answer biological questions that were previously out of reach. Based out of one of the largest mass spectrometry hubs in the United States, the lab relies on a high-performance LC-MS workflow built around the <a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/content/lifetech/global/en/home/industrial/mass-spectrometry/liquid-chromatography-mass-spectrometry-lc-ms/lc-ms-systems/orbitrap-lc-ms/orbitrap-tribrid-mass-spectrometers/orbitrap-ascend-tribrid-mass-spectrometer/systems/orbitrap-ascend-multiomics-tribrid-mass-spectrometer.html"><strong>Thermo Scientific Orbitrap Ascend MultiOmics Tribrid Mass Spectrometer</strong></a><strong> </strong>coupled with a<strong> </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/398"><strong>Thermo Scientific Vanquish Neo UHPLC System</strong></a>.</p><p>Together, these platforms deliver flexible, reproducible separations and enable the integration of ETD, HCD, PTCR, and high-mass analysis within a single experiment. This flexibility is critical when working with limited or precious samples such as enriched cell surface glycoproteins, providing the sensitivity and robustness needed to characterize highly complex glycopeptides and intact glycoproteins.</p><h3><strong>From forensics to glycoproteomics</strong></h3><p>Riley’s scientific path began in undergraduate chemistry and psychology, where an early interest in forensics led him to mass spectrometry. Rather than focusing on applications, he became interested in the instruments themselves.</p><p>That fascination took him to the University of Wisconsin-Madison, where he trained in Josh Coon’s lab and worked extensively on electron transfer dissociation. While developing new fragmentation methods, Riley encountered glycopeptides almost by accident and quickly realized their complexity and importance.</p><p>A postdoctoral position in Carolyn Bertozzi’s lab at Stanford deepened his exposure to glycobiology and reinforced his interest in building tools that allow scientists to better interrogate biological systems. That philosophy now defines his research program at the University of Washington.</p><h3><strong>Why flexibility matters in glycoproteomics</strong></h3><p>Glycoproteomics presents unique analytical challenges. Glycans increase molecular heterogeneity, complicate ionization, and require multiple fragmentation strategies to fully characterize.</p><p><i>“There’s no single method that can answer all of our questions,”</i> Riley explains. <i>“We need flexibility at every level.”</i></p><p>For the Riley Group, that flexibility comes from advanced LC-MS platforms, particularly Tribrid instruments like the <strong>Orbitrap Ascend Mass Spectrometer</strong>. These systems allow his team to combine ETD, HCD, PTCR, and high-mass analysis within a single workflow.</p><p>That versatility is essential when working with limited samples, especially in experiments involving cell surface glycoproteins or double enrichment strategies.</p><h3><strong>Turning technology into biological insight</strong></h3><p>One recent study highlights how instrumentation directly enables discovery. Riley’s team investigated how glycosylation affects protein corona formation using SEER nanoparticles. The workflow required two enrichment steps, leaving very little material for analysis.</p><p>Using the Orbitrap Ascend Mass Spectrometer’s real-time library search capabilities, the team developed <strong>Autonomous Dissociation Type Selection</strong>, a method that uses real-time decision making to determine the optimal fragmentation method during acquisition. This approach allowed the team to extract comprehensive information from a single LC-MS injection, preserving sample while accelerating discovery.</p><p><i>“That kind of experiment simply wouldn’t be possible without real-time decision making on the instrument,”</i> says Riley.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_What_Happens_When_Glycoproteomics_Meets_Real_Time_LC_MS_Decision_Making_2_f5c7de51c3.jpeg" alt="Thermo Fisher Scientific: What Happens When Glycoproteomics Meets Real-Time LC-MS Decision Making?: Kayla Markuson, B.S., is one of the grad students in the Riley Group. She was recipient of the 2025 Thermo Scientific Quantitative Proteomics Research Grant Program." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_What_Happens_When_Glycoproteomics_Meets_Real_Time_LC_MS_Decision_Making_2_f5c7de51c3.jpeg 208w," sizes="100vw" width="1024" height="768"></p><h3><strong>Lowering barriers, training scientists</strong></h3><p>Beyond enabling specific experiments, Riley sees advanced instrumentation as a way to democratize complex methodologies. Techniques like ETD, once difficult to reproduce, are now robust and accessible.</p><p>That shift has a direct impact on training. Students in Riley’s lab are encouraged to design experiments around unanswered biological questions rather than technical constraints.</p><p><i>“When the instrument isn’t the bottleneck, creativity becomes the skill you’re really teaching,” </i>he notes. <i>“That’s how you prepare scientists for the future.”</i></p><h3><strong>Looking ahead</strong></h3><p>As instrumentation continues to evolve, Riley believes the next breakthroughs will come from increased sensitivity, richer fragmentation strategies, and smarter data analysis. The ultimate goal is not just better measurements, but deeper biological understanding.</p><p><i>“Glycoproteomics demands multiple analytical strategies,”</i> Riley explains. <i>“We need to move seamlessly between different fragmentation methods, mass ranges, and separation conditions. The Ascend paired with the Vanquish Neo gives us that freedom.”</i></p><p><i>“Technology should expand the questions we can ask,”</i> he says. <i>“That’s when real discovery happens.”</i></p><p>&nbsp;<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_What_Happens_When_Glycoproteomics_Meets_Real_Time_LC_MS_Decision_Making_3_ced9ad52e2.jpeg" alt="Thermo Fisher Scientific: What Happens When Glycoproteomics Meets Real-Time LC-MS Decision Making?: Lab members pictured left to right in front of Riley Group’s Thermo Scientific Orbitrap Ascend MultiOmics Tribrid Mass Spectrometer coupled with a Thermo Scientific Vanquish Neo UHPLC System: Nick Riley, Emmajay Sutherland, Jacob Russell, Tim Veth, Kayla Markuson." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_What_Happens_When_Glycoproteomics_Meets_Real_Time_LC_MS_Decision_Making_3_ced9ad52e2.jpeg 208w," sizes="100vw" width="768" height="576"></p><blockquote><p><strong>Visit us on&nbsp;</strong><a target="_blank" rel="noopener noreferrer" href="https://www.linkedin.com/showcase/72003132/admin/dashboard/"><strong><u>LinkedIn:</u></strong></a>&nbsp;#Glycoproteomics #MassSpectrometry #LCMS</p></blockquote>

What Happens When Glycoproteomics Meets Real-Time LC-MS Decision Making?

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The International Symposium on Chromatography (ISC) represents the oldest conference series focussing on separation science. ISC symposia have been organised since 1956 in each even year. ISC is internationally recognised as one of the premier meeting series for discussion of all modes of chromatography and separation science with a broad coverage of techniques and applications.

International Symposium on Chromatography - (ISC)

The HTC symposium series started in 1990 and is the ideal meeting place for scientists and practitioners from academia and industry and vendors to discuss and gather new insights in emerging technologies, instrumentation, workflows, and applications. Organized under the auspices of the Vrije Universiteit Brussel (VUB), the Catholic University of Leuven (KU Leuven), Ghent University (UGhent), and the Separation Science Group of the Royal Society of Chemistry (RSC), HTC-19 is expected to gather over 300 participants.

International Symposium on Hyphenated Techniques in Chromatography and Separation Technology

Waters ACQUITY QDa II Mass Detector

The ACQUITY™ QDa™ II Mass Detector enhances efficiency and productivity in separations workflows with advanced technology.

<h3><strong>Advancing the Power of Mass Detection</strong></h3><ul><li><strong>Identify Everything in Your Sample with Complete Confidence&nbsp;</strong></li></ul><h5><strong>Information-rich mass spectral data starts here&nbsp;</strong></h5><p><strong>Built on a solid foundation of groundbreaking technology, the ACQUITY™ QDa™ II Mass Detector provides even more efficiency and productivity of separations workflows, providing information-rich mass spectral data, ensuring compliance, and regulatory certainty.</strong></p><h4><strong>SEE MORE COMPOUNDS</strong></h4><p>Greater compound coverage from an extended mass range to support small molecules, large molecules and new modalities. A complementary technique to analog detection for chemicals with no chromophores, ACQUITY QDa II Mass Detector enables you to confirm the identity and purity of more compounds with the power of mass detection.</p><h4><strong>ANALYZE MORE SAMPLES</strong></h4><p>Robust, reliable and requiring no sample-specific adjustment. Simply power on to make informed decisions with the full picture of what’s in your sample. Minimal maintenance along with system performance monitoring ensures maximum uptime.&nbsp;</p><h4><strong>HAVE MORE CONFIDENCE IN THE ROBUSTNESS OF YOUR SEPARATIONS</strong></h4><p>The addition of mass detection to your method development workflow enables fast peak tracking and greater confidence in peak purity, for more robust separations. Combined with industry-leading AQbD method development software, your lab can achieve unprecedented MS peak tracking functionality with the ACQUITY QDa II Mass Detector.</p><h4><strong>STRIVE FOR MORE SUSTAINABILITY</strong></h4><p>Achieve up to a 70% reduction in energy consumption and heat output compared to other vendor’s MS systems. 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Designed for compatibility with your chromatography." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_ACQUITY_Q_Da_II_Mass_Detector_The_Perfect_Partner_Designed_for_compatibility_with_your_chromatography_1042adecb0.jpg 189w," sizes="100vw" width="1299" height="1074"></p><h3><strong>Effortless Integration</strong></h3><h4><strong>Achieve more with flexible software solutions</strong></h4><p>Process, Interpret, visualize, and compare the most complex data, and turn it into meaningful information quickly and simply. With integrated optical and mass detector data processing workflows, you can also analyze mass spectral data in the same way as you do photo diode array (PDA) data.</p><p>The ACQUITY QDa II Mass Detector is fully compatible with Masslynx™ Software and its suite of data processing application managers. 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With a suite of flexible functionalities that grows to meet your changing quality, business, and laboratory needs, Empower CDS has been purposefully designed to help you address your most demanding chromatographic, regulatory, and networking challenges.</p><h4><strong>EMPOWER LAB MANAGEMENT SYSTEM (LMS)</strong></h4><p>Automating your lab workflow, from sample creation to data archival, is critical for maintaining data integrity and enhancing productivity. Manage your data all from a single, simple dashboard for an integrated approach to your product lifecycle management so you can reduce transcription errors, increase efficiency, and maximize data durability.</p><h4><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1544"><strong>waters_connect™</strong></a><strong> SYSTEM MONITORING</strong></h4><p>Monitor all Empower Software-controlled chromatography systems remotely, at any time, from anywhere. Dynamically plan laboratory activities, monitor the status of your laboratory and maximize productivity. Troubleshoot and respond to errors faster, increasing system uptime.</p><h3><strong>Identify More in Released Glycan Analysis</strong></h3><h4><strong>Unlock the full potential of your QC glycan testing</strong></h4><p>While non-MS methods offer routine QC capabilities, they fall short in delivering the detailed characterization, crucial for biopharmaceutical development. The ACQUITY QDa II Mass Detector with extended mass range revolutionizes routine analysis, offering accurate QC monitoring of N-glycan species with speed and precision. Coupled with Waters chromatography systems, enjoy enhanced MS response with uniform charge state for accurate quantitation, enabling scrutiny of released N-glycan profiles in under 40 minutes per sample. Complement fluorescence (FLR) detection and embrace reproducible, quantitative separation for rapid decision-making.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_ACQUITY_Q_Da_II_Mass_Detector_Selected_Ion_Recording_SIR_chromatogram_of_doubly_charged_components_of_a_glycan_sample_Highlighted_additional_components_identified_s_a_result_of_the_extended_mass_range_ac0160e74d.jpg" alt="Waters ACQUITY QDa II Mass Detector: Selected Ion Recording (SIR) chromatogram of doubly charged components of a glycan sample. Highlighted additional components identified s a result of the extended mass range." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_ACQUITY_Q_Da_II_Mass_Detector_Selected_Ion_Recording_SIR_chromatogram_of_doubly_charged_components_of_a_glycan_sample_Highlighted_additional_components_identified_s_a_result_of_the_extended_mass_range_ac0160e74d.jpg 238w," sizes="100vw" width="1347" height="883"></p><h3><strong>Unparalleled Robustness for More Qualitative and Quantitative Performance</strong></h3><h4><strong>Reduce the risk of genotoxic impurities formation in drug manufacturing</strong></h4><p data-start="0" data-end="296">Support risk assessment through routine monitoring of excipients and raw materials in drug manufacturing. Accessible, regulatory compliant-ready LC-MS solutions provide an efficient and cost-effective approach in mitigating the risk of impurity formation during the manufacture of drug product.</p><p data-start="298" data-end="768">Nitrite, a critical risk factor in N-Nitrosamine formation, presents as an impurity in pharmaceutical excipients, often in parts per million (ppm). The ACQUITY QDa II Mass Detector is a robust and reliable solution for routine analysis of nitrite in excipients. With automated resolution, tuning, and calibration during start-up, the ACQUITY QDa II Mass Detector eliminates the need for analyst intervention, ensuring seamless operation and precise results every time.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_ACQUITY_Q_Da_II_Mass_Detector_Over_29_days_of_rigorous_testing_it_flawlessly_executed_approximately_6000_injections_with_minimal_downtime_02a496f422.jpg" alt="Waters ACQUITY QDa II Mass Detector: Over 29 days of rigorous testing, it flawlessly executed approximately 6000 injections with minimal downtime." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_ACQUITY_Q_Da_II_Mass_Detector_Over_29_days_of_rigorous_testing_it_flawlessly_executed_approximately_6000_injections_with_minimal_downtime_02a496f422.jpg 245w," sizes="100vw" width="1185" height="529"></p><p data-start="770" data-end="1012" data-is-last-node="" data-is-only-node="">Empower CDS reporting functionality offers simple reviewing of excipient nitrite concentration within a sample batch. This allows for fast and comprehensive decision making, while ensuring compliance and data integrity within your laboratory.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_ACQUITY_Q_Da_II_Mass_Detector_Example_of_Empower_CDS_generated_data_report_for_nitrite_content_in_a_maize_starch_sample_2f106193ee.jpg" alt="Waters ACQUITY QDa II Mass Detector: Example of Empower CDS generated data report for nitrite content in a maize starch sample." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_ACQUITY_Q_Da_II_Mass_Detector_Example_of_Empower_CDS_generated_data_report_for_nitrite_content_in_a_maize_starch_sample_2f106193ee.jpg 245w," sizes="100vw" width="937" height="585"></p><h3><strong data-start="0" data-end="62">Improving Efficiency with a More Sustainable Mass Detector</strong></h3><h4><strong>Low operational costs and environmental footprint</strong></h4><p data-start="123" data-end="346"><strong>As a leading technology innovator in chromatography, mass spectrometry, and thermal analysis instruments and software, Waters shares a common mission with our customers: to leave the world a better place than we found it.</strong></p><p data-start="348" data-end="674" data-is-last-node="" data-is-only-node="">Many of our customers are actively working to address environmental sustainability in balance with the need to continually reduce operational costs. Waters has addressed these challenges by providing an instrument with low electricity consumption and BTU/hr output – lessening the need for air conditioning and lowering costs.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_ACQUITY_Q_Da_II_Mass_Detector_Improving_Efficiency_with_a_More_Sustainable_Mass_Detector_Low_operational_costs_and_environmental_footprint_a9e182ea1f.jpg" alt="Waters ACQUITY QDa II Mass Detector: Improving Efficiency with a More Sustainable Mass Detector. Low operational costs and environmental footprint." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_ACQUITY_Q_Da_II_Mass_Detector_Improving_Efficiency_with_a_More_Sustainable_Mass_Detector_Low_operational_costs_and_environmental_footprint_a9e182ea1f.jpg 245w," sizes="100vw" width="1124" height="389"></p><p><strong>*</strong>From competitor A Specification Sheet.</p><p><strong>**</strong>From competitor B Site Preparation Checklist</p><h3><strong>Unrivaled Support</strong></h3><h3><strong>Ensure your success with world-renowned services</strong></h3><p data-start="77" data-end="464" data-is-last-node="" data-is-only-node="">Waters Service and Support helps maintain peak system performance, minimize downtime, address scientific challenges, and meet compliance requirements.&nbsp;</p><p>Waters award-winning consistent quality support, professional services, and education ensure your success wherever your laboratory is located in the world. With Waters service and support offerings<strong>*</strong> for your ACQUITY QDa II Mass Detector, you can</p><h4><strong data-start="0" data-end="30">GET UP AND RUNNING QUICKLY</strong></h4><p data-start="0" data-end="235">Get the onsite training and consultation you need to integrate the ACQUITY QDa II Mass Detector into your laboratory and assist with data migration and method transfer needs with Waters Professional Services.</p><h4><strong data-start="237" data-end="276">MEET YOUR LAB’S UNIQUE REQUIREMENTS</strong></h4><p data-start="237" data-end="460">Protect your instrument investment with the comprehensive portfolio of service plans from Waters FlexCHOICE™, which provides access to the most in-depth and up-to-date knowledge of the advanced science and technologies within Waters systems.</p><h4><strong data-start="462" data-end="487">FACILITATE COMPLIANCE</strong></h4><p data-start="462" data-end="635">Simplify the process of qualification, and record-keeping so that your business can focus on delivering products to market with Waters Compliance Services – so you can meet the regulations in your industry and in the countries where you conduct business.</p><h4><strong data-start="637" data-end="671">REDUCE TOTAL COST OF OWNERSHIP</strong></h4><p data-start="637" data-end="864">FlexCAPITAL™ <strong>**</strong> is designed to support continuous laboratory operation while satisfying the budgeting challenges of a constantly shifting landscape. Minimize total cost of ownership while optimizing instrument performance and protecting your organization from security risks associated with outdated software platforms.</p><h4><strong data-start="866" data-end="903">LEVERAGE YOUR EXISTING TECHNOLOGY</strong></h4><p data-start="866" data-end="1104" data-is-last-node="" data-is-only-node="">With the FlexUP™ Technology renewal program, you can upgrade your older single quadrupole mass spectrometry system to the ACQUITY QDa II Mass Detector -- improving performance, results, and productivity while controlling costs and mitigating compliance risk.</p><p><strong>*</strong> Availability of offerings varies by country. Contact Waters or your local Waters representative for details<br><strong>**</strong> FlexCAPITAL payment plan options and availability may vary by country. Other restrictions may apply.</p>

Waters RADIAN ASAP Direct Mass Detector

Combining flexibility, ease of operation, and speed without the need for complex sample preparation, separation or extensive MS experience, the RADIAN ASAP helps you and your laboratory achieve more.

<div><div id="title-a9e634f6cb" data-locator="title-with-text"><h3><strong>The power of knowing now</strong></h3></div></div><div><div id="text-c687cac6aa" data-locator="text"><p><strong>Whether you are looking to improve your drug discovery cycle, expand your client services, or simply become more competitive in your turnaround times, integrating direct mass spectrometry (MS) analysis can drive multiple system-wide efficiencies helping to achieve your operational goals.</strong></p><p>Combining flexibility, ease of operation, and speed without the need for complex sample preparation, separation or extensive MS experience, the RADIAN ASAP helps you and your laboratory achieve more.</p><ul><li>Simple operation and data interpretation</li><li>Minimal sample preparation</li><li>No separation required</li><li>Real-time results and classification</li></ul><figure class="image"><img style="aspect-ratio:454/321;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_RADIAN_ASAP_7cfe24b23d/Waters-RADIAN-ASAP_s.webp" alt="Waters RADIAN ASAP Direct Mass Detector" width="454" height="321"></figure><h3><strong>Overview</strong></h3><div data-locator="section-container-body"><div><div><div data-locator="layoutcontainer-"><div><div id="text-6b896f6da4" data-locator="text"><ul><li>Ensure users get up and running quickly with RADIAN ASAP’s easy to learn and fully automated set up, streamlined workflow, and minimal training requirements</li><li>Minimize sample prep with direct sampling onto glass probe</li><li>Minimize the need for solvent use and disposal with no chromatography</li><li>Save time with 30 second analysis and real-time sample classification</li></ul></div></div><div><div id="text-161a2a5c01" data-locator="text"><h4><strong>Recommended Use</strong></h4><p>For rapid, easy, and low-cost analysis of liquids and solids.</p><div><div id="text-4973311325" data-locator="text"><h3 data-locator="modal-title"><strong>Compact without compromise</strong></h3><p>The RADIAN ASAP is a novel, dedicated direct analysis system specifically designed for rapid, easy and low-cost analysis of liquids and solids. Engineered using proven and robust single quadrupole mass spectrometry technology combined with the Atmospheric Pressure Solids Analysis Probe (<a target="_blank" rel="noopener noreferrer" href="https://www.waters.com/nextgen/us/en/services/instrument-services/instrument-upgrades/mass-spectrometry-ms-upgrades/atmospheric-solids-analysis-probe.html" data-di-id="di-id-70d78c77-7e033f9d">ASAP</a>), the RADIAN ASAP delivers quality and ease of use in a compact footprint.&nbsp;</p><p>This single quadrupole mass detector provides high quality mass spectral data, without the need for any special training or expertise, eliminating any need to contract out and wait for results from specialist analytical service laboratories.</p></div></div><div><div id="text-08366f2c0d" data-locator="text"><h3 data-locator="modal-title"><strong>Flexible workflow solutions in 4 simple steps</strong></h3><p>Operation of the RADIAN ASAP is simple and intuitive, allowing users to generate results with minimal or no sample preparation, making it an ideal tool for laboratories to make informed decisions. Capable of ionizing molecules directly from a liquid or solid makes the system available to a wide range of applications and workflows.</p><h4><strong>Generate results in 4 simple steps:</strong></h4><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_RADIAN_ASAP_analyza_ve_4_jednoduchych_krocich_a997bfddda/Waters-RADIAN-ASAP-analyza-ve-4-jednoduchych-krocich.jpg" alt="Waters RADIAN ASAP Direct Mass Detector: Flexible workflow solutions in 4 simple steps" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_RADIAN_ASAP_analyza_ve_4_jednoduchych_krocich_a997bfddda/thumbnail_Waters-RADIAN-ASAP-analyza-ve-4-jednoduchych-krocich.jpg 245w," sizes="100vw" width="1683" height="490"></p><h3><strong>Ideal for numerous application requirements</strong></h3><p><a target="_blank" rel="noopener noreferrer" href="https://www.waters.com/waters/nav.htm?cid=135078611" data-di-id="di-id-7f758d90-ccee23de"><strong>Rapid triage of seized drug materials for Forensics</strong></a><i>&nbsp;<strong>—</strong>&nbsp;</i>RADIAN ASAP and LiveID ensure crime labs can quickly screen samples against a library of known compounds for rapid, confident identification of illicit drugs. The sensitivity and selectivity of mass spectrometry provides confidence in detecting drugs with an easy, efficient triage workflow.</p><p><a target="_blank" rel="noopener noreferrer" href="https://www.waters.com/waters/nav.htm?cid=134528742" data-di-id="di-id-3a3c46e4-ccee23de"><strong>Assess food integrity for Food &amp; Environmental</strong></a>&nbsp;<strong>—</strong> The threat posed by food fraud has created additional demands on both the food industry and regulators to protect food consumers and maintain brand reputation. RADIAN ASAP and LiveID offer a powerful combination of mass spectrometry and chemometric modeling, allowing users to easily and efficiently screen samples and make quicker decisions.</p><p><a target="_blank" rel="noopener noreferrer" href="https://www.tainstruments.com/radian-asap-direct-mass-detector/" data-di-id="di-id-2fac456-44144a9d"><strong>Fast chemical analysis for improved formulation testing in Chemical and Materials</strong></a><i>&nbsp;<strong>—</strong>&nbsp;</i>RADIAN ASAP and IonLynx supports quality control (QC) and development labs in the chemical industry to reduce costs and increase efficiencies. Streamline workflows like fast chemical analysis for improved formulation testing or&nbsp;material release testing. Features including thermal gradient analysis are ideal for the complex samples in the chemical industry.</p><p><a target="_blank" rel="noopener noreferrer" href="https://www.waters.com/waters/nav.htm?cid=134751395" data-di-id="di-id-76921eaa-ccee23de"><strong>Discovery reaction monitoring&nbsp;for Pharma</strong></a>&nbsp;<strong>—</strong> The demand to accelerate the drug discovery and development process has never been higher.&nbsp;RADIAN ASAP provides synthetic chemists easy access to mass spectral data for near-instantaneous assessment of reaction progress and identification of purification fractions, increasing lab efficiency.</p><div><div><div><div id="text-8b0fa56c8c" data-locator="text"><p><a target="_blank" rel="noopener noreferrer" href="https://www.waters.com/waters/nav.htm?cid=134971387" data-di-id="di-id-10e51f17-ccee23de"><strong>Undergraduate teaching&nbsp;and method development&nbsp;in Academia</strong></a><strong> —&nbsp;</strong>Simplicity and ease of use makes RADIAN ASAP the ideal tool for busy academic laboratories that need a robust and reliable solution.</p><figure class="image"><img style="aspect-ratio:474/308;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_RADIAN_ASAP_2_87ddc46f15/Waters-RADIAN-ASAP-2_s.webp" alt="Waters RADIAN ASAP Direct Mass Detector" width="474" height="308"></figure><div><div id="text-a5e5e26910" data-locator="text"><h3 data-locator="modal-title"><strong>Software solutions for your data requirements</strong></h3><p><strong>RADIAN ASAP</strong> is compatible with software solutions for rapid interpretation and classification as well as automated data processing and reporting.</p><p>For customers investigating the authenticity, adulteration, and quality of food or raw materials, <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library?mainauthorItems=5&amp;search=liveid"><strong>LiveID</strong></a> uses statistical models to classify samples. First, authentic or verified samples are used to create and validate a statistical model. The validated model can then be used with test samples and generate live classifications with a simple yes/no answer output. LiveID can also do real time <strong>library</strong> matching workflows, where the software matches all compounds in the library against each sample analyzed, giving a score out of <strong>1000</strong>, where values close to 1000 indicate the compound of interest is likely in the sample and lower scores indicate unlikely presence in the sample.</p><p><strong>OpenLynx</strong> processing provides user customizable processing capabilities to generate automated mass confirmation reports in either pdf, printed or browser format.&nbsp;</p><p><strong>IonLynx</strong> allows users to determine levels and relative ratios of analytes of interest in complex samples to aid decision making in QC and formulation monitoring. IonLynx provides automated processing and reporting of non-chromatographic data sets, such as those generated by RADIAN ASAP.</p></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div>

Thermo Scientific ISQ™ EC/EM Single Quadrupole Mass Spectrometer

Enhance your IC or LC analysis with ISQ EC/EM mass spectrometers. Enjoy fast setup, high sensitivity, and reliable quantification—even in complex samples—with easy, seamless system integration.

<h4><strong>Thermo Scientific™ ISQ™ EC Single Quadrupole Mass Spectrometer</strong></h4><p><strong>Add mass spectrometry (MS) to your IC and LC analyses for access to the valuable data that only MS can provide. The new, easy-to-use Thermo Scientific™ ISQ™ EC Single Quadrupole Mass Spectrometer seamlessly integrates with ion chromatography (IC) and high performance liquid chromatography (HPLC) systems. Both novices and experts alike can quickly master MS to gain more insights from every sample.</strong></p><h5><strong>Gain more insights</strong></h5><ul><li>Higher sensitivity and more accurate quantitation</li><li>Chromatographic peak mass confirmation, eliminating false negatives and false positives</li></ul><h5><strong>Resolve complexity</strong></h5><ul><li>Improved resolution of analytes in complex matrices</li><li>Better selectivity</li><li>Resolve co-eluting peaks using their mass-to-charge ratio</li></ul><h5><strong>Easily mastered</strong></h5><ul><li>Save time spent on user training with integrated tools to help master MS</li><li>Experience hassle-free, seamless integration with your IC or LC system</li><li>Save time using the Thermo Scientific™ <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/76"><strong>Chromeleon™ Chromatography Data System (CDS) software</strong></a> for data analysis, which also has embedded control of the ISQ EC mass spectrometer</li></ul><h4><strong>Thermo Scientific™ ISQ™ EM Single Quadrupole Mass Spectrometer</strong></h4><p>Adding mass spectrometry (MS) to your liquid chromatography (LC) analyses gives you access to the valuable data that only MS can provide. The new, easy-to-use ISQ™ EM Single Quadrupole Mass Spectrometer seamlessly integrates with LC systems for reliable, robust, and easy LC-MS routine analysis with an extended mass range for more flexibility. Detect and quantify a variety of analytes by choosing to use either heated electrospray ionization (HESI) or atmospheric pressure chemical ionization (APCI). Integrated software allows both novices and experts to quickly master MS to gain more insights from every sample.</p><h5><strong>Gain more insights</strong></h5><ul><li>Extended mass range enables you to detect and quantify small and large molecules</li><li>Durable atmospheric pressure ionization (API) source with two interchangeable probes included, enabling HESI or dual HESI/APCI</li><li>Sensitive and accurate quantitation of more samples</li><li>Chromatographic peak mass confirmation to eliminate false negatives and false positives</li></ul><h5><strong>Resolve complexity</strong></h5><ul><li>Consistent response even with complex matrices</li><li>Better selectivity and sensitivity with chromatographic peak mass confirmation</li><li>Resolution of co-eluting peaks via mass-to-charge ratio</li></ul><h5><strong>Easy mastery</strong></h5><ul><li>Reduce time spent on user training with integrated tools to help master MS</li><li>Unique software translates analyte physical properties into optimal method parameters, helping novice and experts develop methods and improve productivity</li><li>Hassle-free, seamless integration with existing LC systems</li><li>Facilitate data analysis with Thermo Scientific™ <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/76"><strong>Chromeleon™ Chromatography Data System (CDS) software</strong></a>, which features embedded control of the ISQ EM mass spectrometer</li></ul><h4><strong>Key Features ISQ™ EC/EM Single Quadrupole Mass Spectrometers:</strong></h4><ul><li><strong>Mass Range:</strong>&nbsp;<ul><li><strong>EC:</strong> 10–1250 m/z with unit mass resolution</li><li><strong>EM:</strong> 10–2000 m/z with unit mass resolution</li></ul></li><li><strong>Polarity Switching:</strong> 25 ms (in HESI mode)</li><li><strong>Scan Rate:</strong> Up to 20,000 Da/sec</li><li><strong>Sensitivity:</strong><ul><li><i>HESI Positive:</i> 10 pg Reserpine, 400:1 RMS at 400 μL/min</li><li><i>HESI Negative:</i> 20 pg p-Nitrophenol, 500:1 RMS at 400 μL/min</li></ul></li><li><strong>Gas Requirements:</strong> Nitrogen (≥ 99% purity), 30 L/min @ 90–110 psig</li><li><strong>Power Supply:</strong> 100–240 V, 50/60 Hz</li><li><strong>Dimensions:</strong> 52 (H) × 42 (W) × 91 (D) cm</li><li><strong>Weight:</strong> Approx. 71 kg (157 lb)</li><li><strong>Unit Size:</strong> Each</li></ul>

Products from category Single quadrupoles focused on LC/SQ - page 1

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