<p><strong>We are pleased to invite you to our upcoming free online webinar on June 11, 2026 focused on one of the most pressing challenges in environmental monitoring and water quality management — PFAS (Per- and Polyfluoroalkyl Substances).</strong></p><p>As regulatory frameworks continue to evolve and compliance deadlines approach, laboratories, water utilities, and environmental professionals need robust, reliable, and cutting-edge analytical solutions to stay ahead.</p><blockquote><p class="cke-user_style-important"><strong>👉</strong><a target="_blank" rel="noopener noreferrer" href="https://events.teams.microsoft.com/event/91d97003-fe33-4dca-b80b-160d9f8a5655@485ca04e-6f74-4050-9764-cdb4bfa89c25"><strong>Registration HERE</strong></a></p></blockquote><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ALS_analyzy_PFAS_a9e4a87fbc.jpg" alt="ALS: Advanced PFAS Analytical Services " srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ALS_analyzy_PFAS_a9e4a87fbc.jpg 245w," sizes="100vw" width="600" height="336"></p><h4><strong>🎤 Our Speaker</strong></h4><p>The webinar will be hosted by <strong>Jana Kováčová, Ph.D., PFAS Regional Lead for Continental Europe Environmental Division</strong>, who has dedicated the last several years to the field of PFAS analysis and determination in ALS laboratories. Jana is a recognized expert in PFAS environmental analytics and will share practical insights and the latest developments in analytical strategies to help your organization achieve and maintain compliance.</p><h4><strong>🎯 What You Will Learn</strong></h4><ul><li>Latest <strong>regulatory developments</strong> and compliance requirements for PFAS in water, including <strong>EU Drinking Water Directive 2020/2184</strong> and its implications for water suppliers and laboratories.</li><li><strong>Regulatory updates for surface water and groundwater</strong> — what's new and what to expect next.</li><li>Overview of <strong>advanced analytical strategies</strong> for PFAS detection and quantification in water matrices and how we analyse PFAS samples.</li><li>Key <strong>analytical challenges</strong> associated with PFAS testing — from ultra-trace detection to matrix interferences and contamination control.</li><li>The critical importance of using tested <strong>sampling containers</strong> and sample preservation to ensure reliable results.</li><li>Illustrative <strong>examples of results</strong> from real-world PFAS water analyses.</li><li>How ALS can support your needs with <strong>accredited PFAS testing services</strong>.</li></ul><h4><strong>👥 Who Should Attend</strong></h4><p>This webinar is designed for our clients, professionals, laboratory and technical staff, scientists, as well as anyone with an interest in analytical chemistry who wants to better understand the occurrence of these "forever chemicals" in the environment. &nbsp;</p><h4><strong>💬 Q&amp;A Session</strong></h4><p>There will be a live Q&amp;A session at the end of the webinar. You are welcome to submit your questions in advance during registration or ask them live on the day.</p><h4><strong>📅 Additional Webinar Info:</strong></h4><ul><li><strong>Platform: </strong>Microsoft Teams (online)</li><li><strong>Time: </strong>10:00 CEST</li><li><strong>Language: </strong>English</li><li><strong>Duration:</strong> approx. 45 - 60 minutes (incl. Q&amp;A)<br>Extras: If you are unable to attend on the day, please register and we will provide you with the recording of the webinar.</li></ul><h4><strong>🔬 About ALS Environmental</strong></h4><p>ALS is a global leader in environmental testing and analytical services, providing accredited PFAS analysis to clients across Europe and beyond. Our dedicated PFAS experts help clients navigate the complex regulatory landscape with confidence.</p><blockquote><p>For further information, please contact us on: <strong>marketing.cz@alsglobal.com</strong></p></blockquote><p>We look forward to welcoming you to this important discussion on PFAS compliance in water.</p>

Invitation to the ALS Webinar PFAS in Water 2026: Achieving Compliance through Advanced Analytical Strategies

<p><strong>Why are switchable 2D-LC workflows fit for mAb manufacturing? Discover a practical AQbD approach for monitoring charge and size variants in one hour.</strong></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Monitoring_m_Ab_Manufacturing_the_Easy_Way_with_Switchable_2_D_LC_UV_MS_689c6925a2.jpeg" alt="Thermo Fisher Scientific: Monitoring mAb Manufacturing the Easy Way with Switchable 2D‑LC-UV-MS." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Monitoring_m_Ab_Manufacturing_the_Easy_Way_with_Switchable_2_D_LC_UV_MS_689c6925a2.jpeg 245w," sizes="100vw" width="1024" height="512"></p><p><strong>Lost material. Delayed production timelines. Reworks across teams.</strong></p><p>If you’re working with monoclonal antibodies (mAbs) or other biopharmaceuticals, you already know the challenge: biological reactions are variable.</p><p>Unlike traditional small-molecule drugs, with simpler and more predictable chemical structures, biotherapeutics exist in a dynamic state of microheterogeneity — no two batches are ever truly identical.</p><p>Whether undergoing production, processing, or storage, these compounds often undergo unwanted side reactions like glycation, deamidation, charge variation, and aggregation, which can compromise product safety and efficacy.</p><p>Finding robust and dependable ways to monitor these critical quality attributes (CQA) and protect therapeutic integrity is even more pressing, as regulatory agencies demand comprehensive characterizations.</p><p>While analytical techniques like liquid chromatography (LC) and mass spectrometry (MS) play a fundamental role in CQA analysis, the increasing complexity of analytical tasks is forcing the requirements of instruments to grow.</p><p>The good news?<strong> </strong><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/blog/analyteguru/biopharma-boost-how-2d-lc-went-from-expert-only-to-routine/"><strong>Targeted two-dimensional LC (2D-LC)</strong></a> workflows that can handle analytical complexity and support straightforward method development without any manual fluidic changes are already here.</p><p>Let’s explore how your lab can use 2D-LC coupled with ultraviolet detection (UVD) or high-resolution accurate mass spectrometry (<a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products?category=22&amp;manufacturerItems=3"><strong>HRAM-MS</strong></a>) to monitor the CQAs of intact mAbs in real time (<strong>Figure 1</strong>).</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Monitoring_m_Ab_Manufacturing_the_Easy_Way_with_Switchable_2_D_LC_UV_MS_2_8ee6b79638.jpeg" alt="Thermo Fisher Scientific: Monitoring mAb Manufacturing the Easy Way with Switchable 2D‑LC-UV-MS: Figure 1. Fluidic scheme of a 2D-LC-MS setup that supports multiple CQA analysis as well as method development without any manual replumbing." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Monitoring_m_Ab_Manufacturing_the_Easy_Way_with_Switchable_2_D_LC_UV_MS_2_8ee6b79638.jpeg 224w," sizes="100vw" width="800" height="559"></p><div><h4><strong>Key takeaways</strong>:</h4><ul><li><strong>Why mAb variants matter</strong></li></ul><p>Physiochemical modifications generate diverse mAb variants — such as deamidated and aggregated species — that require monitoring to protect therapeutic efficacy and safety.</p><ul><li><strong>What switchable 2D-LC brings you</strong></li></ul><p>Switchable heart-cut 2D-LC workflows allow direct upstream monitoring of multiple CQAs during the production cycle from cell culture samples.</p><ul><li><strong>How the separation works</strong></li></ul><p>The mAb is purified from cell culture samples by protein A (ProA) affinity in the first dimension (<sup>1</sup>D). A high-performance strong cation exchange (SCX) column applied in the second dimension (<sup>2</sup>D) facilitates the separation of mAb charge variants or serves as a trap column to focus the purified mAb fraction prior to transfer to size exclusion chromatography (SEC).</p><ul><li><strong>Speed vs. depth: choosing the right detector</strong></li></ul><p>UVD monitoring provides quick and simple trendlines, while the direct coupling of <sup>2</sup>D with HRAM-MS allows deep characterizations and comprehensive insights into glycan profiles, modifications, and aggregates at the intact level.</p><ul><li><strong>Why at-line monitoring matters</strong></li></ul><p>Near real-time analysis of bioreactor samples enables earlier intervention, helping control material costs, improve yield, reduce off-target variants, and avoid costly downtime from rework or restarting production.</p></div><h3><strong>How 2D-LC workflows help streamline mAb manufacturing and prevent costly issues</strong></h3><p>Near real-time monitoring enables early intervention of issues, helping maintain product cost and quality, protect yield, and more consistent downstream performance.</p><p>As best practice, you should begin monitoring product quality attributes (PQAs) from the start of the cell culture and continue daily throughout the process until your reaction reaches the target yield (<strong>Figure 2</strong>).</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Monitoring_m_Ab_Manufacturing_the_Easy_Way_with_Switchable_2_D_LC_UV_MS_3_bb3e594d4a.jpeg" alt="Thermo Fisher Scientific: Monitoring mAb Manufacturing the Easy Way with Switchable 2D‑LC-UV-MS: Figure 2. mAb titer calibration curve (left) and titer determination of cell culture samples from 1D ProA-UV (right). Samples were drawn from the bioreactors over 10 days." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Monitoring_m_Ab_Manufacturing_the_Easy_Way_with_Switchable_2_D_LC_UV_MS_3_bb3e594d4a.jpeg 245w," sizes="100vw" width="768" height="282"></p><p>For established reactions, you can track changes in titer, charge, or size variant profiles based on UV spectral patterns quickly adjust feeds or cell harvest timing to prevent further issues during downstream processing.</p><p>Trends like the formation of new shoulders, slight peak shifts, or loss in peak intensity often signal changes in media composition, nutrient availability, pH, or process stress <strong>(Figure 3</strong>).</p><p><strong>For example:</strong></p><ul><li>Emerging acidic or basic species may indicate chemical modifications, like glycation, deamidation, or other stress‑related changes.</li><li>Size variants can reflect fragmentation or aggregation driven by temperature, agitation, or hold times.</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Monitoring_m_Ab_Manufacturing_the_Easy_Way_with_Switchable_2_D_LC_UV_MS_4_44dd018404.jpeg" alt="Thermo Fisher Scientific: Monitoring mAb Manufacturing the Easy Way with Switchable 2D‑LC-UV-MS: Figure 3. 2D chromatogram of ProA-SCX-SEC analysis of harvested cell culture samples drawn on days 2 and 9." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Monitoring_m_Ab_Manufacturing_the_Easy_Way_with_Switchable_2_D_LC_UV_MS_4_44dd018404.jpeg 204w," sizes="100vw" width="768" height="587"></p><h3><strong>Why switchable workflows provide a simpler path to fewer surprises, faster course corrections, and more consistent mAb production</strong></h3><p>Fortunately,&nbsp;you&nbsp;don’t&nbsp;need a complicated,&nbsp;manual&nbsp;multistep&nbsp;analysis pipeline to keep your mAb production schedule on track. A streamlined, switchable 2D-LC-UV-MS workflow gives you fast, actionable insights—straight from the bioreactor<i>.</i>&nbsp;</p><p>The setup includes a<strong> </strong><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/content/lifetech/global/en/home/industrial/chromatography/liquid-chromatography-lc/hplc-uhplc-systems/vanquish-simple-switch-2d-lc.html"><strong>switchable fluidic design</strong></a> that lets you toggle between charge (SCX) and size variant analysis (SEC) without replumbing the hardware, providing complementary information.</p><p>This convenient approach <a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/watch?v=xOzYpxWbvQw"><strong>combines cleanup and analysis in one system</strong></a>, eliminating manual sample preparation and enabling direct analysis of cell culture supernatants from the bioreactor (<strong>Figure 4</strong>).</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Monitoring_m_Ab_Manufacturing_the_Easy_Way_with_Switchable_2_D_LC_UV_MS_5_d6dc6b0059.jpeg" alt="Thermo Fisher Scientific: Monitoring mAb Manufacturing the Easy Way with Switchable 2D‑LC-UV-MS: Figure 4. Quality attribute monitoring of mAb biosynthesis by switchable 2D-LC-UV or MS workflow." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Monitoring_m_Ab_Manufacturing_the_Easy_Way_with_Switchable_2_D_LC_UV_MS_5_d6dc6b0059.jpeg 245w," sizes="100vw" width="768" height="215"></p><h4><strong>How switchable 2D-LC technology works:</strong></h4><ul><li><strong><sup>1</sup>D.</strong> ProA affinity chromatography for titer determination and isolation of the mAb from host cell material and media components. The purified fraction is then sent via automated heart‑cut transfer straight into the <sup>2</sup>D. The <sup>1</sup>D elution conditions facilitate optimal mAb capture at the SCX column in the <sup>2</sup>D.</li><li><i><strong>ProA‑SCX to see charge drifts</strong>. </i>Gradient elution of the SCX column in the <sup>2</sup>D to separate acidic and basic variants from the main peak.</li><li><strong>ProA‑SCX‑SEC to see aggregation risks</strong>. The SCX column is switched in line with the SEC column to resolve the monomer, low‑molecular‑weight (LMW), and high‑molecular‑weight (HMW) fractions. The SCX column here acts as a trap and refocusing stage, releasing the mAb into SEC in a narrow band by a step increase to high ionic strength. The trap/elute procedure is critical to yield sharp peaks downstream, as SEC cannot refocus bands, broadened by the loop volume.</li></ul><p>Together, these workflows support both early risk detection and informed corrective action without adding analytical complexity.</p><h3><strong>UVD or MS? How to pick the right tool for the job</strong></h3><p>With switchable 2D-LC workflows, you can select different detection options in the <sup>2</sup>D: UVD or HRAM-MS (<strong>Figure 5</strong>). The fluidic setups differ slightly, but you must always use a fully volatile buffer system with the MS option.</p><h4><strong>Here’s how to choose the right setup:</strong></h4><ul><li><strong>UVD</strong> is ideal for routine, in‑time process control of established reactions. Provides <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_004276_hplc_vanquish_heartcut_2dlc_antibody_bioproduction_processes_an004276_na_en_201cb3360f.pdf"><strong>quick and simple</strong></a> trendlines when you need clear thresholds to act on, as well as straightforward decisions when you need day-to-day control of established processes. Like the “traffic light” for your production.</li><li><strong>HRAM-MS </strong>is best when you need detailed native intact‑level confirmation, glycoform profiling, or deeper characterization of modifications <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_003310_hplc_vanquish_2dlc_quality_attributes_mabs_an003310_na_en_8caddf8c25.pdf"><strong>during the development stage</strong></a> (<strong>Figure 5</strong>).</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Monitoring_m_Ab_Manufacturing_the_Easy_Way_with_Switchable_2_D_LC_UV_MS_6_d039a60ac0.jpeg" alt="Thermo Fisher Scientific: Monitoring mAb Manufacturing the Easy Way with Switchable 2D‑LC-UV-MS: Figure 5. Coupling to UVD or HRAM MS in 2D charge variant analysis. Left: quick and straightforward batch comparison with the ProA-SCX-UV. Right: ProA-SCX-HRAM MS provides deep insights into glycoforms and modifications at the intact mass level." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Monitoring_m_Ab_Manufacturing_the_Easy_Way_with_Switchable_2_D_LC_UV_MS_6_d039a60ac0.jpeg 245w," sizes="100vw" width="768" height="232"></p><h3><strong>Operational benefits your entire team can trust</strong></h3><p>Real-time monitoring of mAb CQAs reveals when you need to intervene and implement a bioprocess change, protecting you from the most expensive surprises: scrap costs, poor yield, off-target product, and the downtime it takes to clean and start over.</p><p>From an operations perspective, the benefits of switchable 2D-LC workflows are clear and practical (<strong>Figure 6</strong>).</p><ul><li>A single system performs at-line cleanup and analysis, reducing manual handling and process variability.</li><li>Heart-cut transfer minimizes sample loss and contamination risk, while the switchable design provides fit-for-purpose flexibility and delivers comprehensive insight into charge and size variants within one hour.</li><li>Regular daily sampling of crude cell culture supernatants directly from the bioreactor builds reliable trendlines over time.</li><li>Operators can quickly identify batch-divergent behavior using UVD to support timely process adjustments or perform deeper molecular characterization with HRAM MS.</li><li>A standardized, switchable workflow also supports method transfer across teams and sites, reducing variability during scale-up and method transfer.</li></ul><p>Fewer surprises, faster course corrections, and scaling operations without expert guidance are something analysts, engineers, quality control, finance, and regulatory bodies can all get behind.</p><h5><strong>Interested in using switchable 2D-LC workflows for your mAb manufacturing processes?</strong></h5><p>See real bioreactor data and step-by-step setup details in our application notes today.</p><ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_004276_hplc_vanquish_heartcut_2dlc_antibody_bioproduction_processes_an004276_na_en_201cb3360f.pdf"><strong>Switchable 2D-LC-UV workflows for routine monitoring</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_003310_hplc_vanquish_2dlc_quality_attributes_mabs_an003310_na_en_8caddf8c25.pdf"><strong>Switchable 2D-LC-MS workflows for deeper characterizations</strong></a></li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Monitoring_m_Ab_Manufacturing_the_Easy_Way_with_Switchable_2_D_LC_UV_MS_7_d8882ed8ae.jpeg" alt="Thermo Fisher Scientific: Monitoring mAb Manufacturing the Easy Way with Switchable 2D‑LC-UV-MS: Figure 6. Illustration showing how switchable 2D-LC works." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Monitoring_m_Ab_Manufacturing_the_Easy_Way_with_Switchable_2_D_LC_UV_MS_7_d8882ed8ae.jpeg 245w," sizes="100vw" width="768" height="384"></p><h3><strong>Frequently asked questions</strong></h3><div><div><h5><strong>1. What mAB quality control attributes should I monitor my reaction for regulatory?</strong></h5><p>Some of the most important critical quality attributes of cell culture derived samples you should monitor include mAb titer, charge and size variants, and glycosylation profiles.</p></div><div><h5><strong>2. What is 2D-LC?</strong></h5><p>2D-LC&nbsp;is a technique that successively uses two complementary LC modes for a multi-dimensional separation. Traditionally such systems are used for additional selectivity to help resolve complex separations or to deplete interfering matrices.</p></div><div><h5><strong>3. What is the benefit of using a switchable 2D-LC workflow for mAb manufacturing?</strong></h5><p>Switchable heart-cut 2D-LC workflows facilitate toggling&nbsp;between size and charge variant&nbsp;analysis of the intact mAb under native conditions — directly from cell culture samples — without reconfiguring&nbsp;the&nbsp;hardware.</p></div><div><h5><strong>4. Should I use UVD or MS during mAb manufacturing?</strong></h5><p>UVD supports quick, efficient decisions during production progression and is ideal for monitoring well-established biosynthetic processes. HRAM-MS allows for a deep characterization and comprehensive insights into glycan profiles, modifications, and aggregates at the intact level.</p></div></div><blockquote><p><strong>Visit us on&nbsp;</strong><a target="_blank" rel="noopener noreferrer" href="https://www.linkedin.com/showcase/72003132/admin/dashboard/"><strong><u>LinkedIn:</u></strong></a><strong>&nbsp;</strong>#ChargeVariantAnalysis, #HRAM, #LiquidChromatography</p></blockquote>

Monitoring mAb Manufacturing the Easy Way with Switchable 2D‑LC-UV-MS

<p><span><strong>Time is running out to take advantage of discounted registration fees for the 19th Czech-Slovak Spectroscopic Conference (19th CSSC), one of the leading scientific events dedicated to spectroscopy and spectrometry in Central Europe. Researchers, students, instrument specialists, and industry professionals are invited to join the conference at the Faculty of Science, Palacký University Olomouc. The Early Bird registration period and the deadline for lecture and poster abstract submission both end on June 15, 2026.&nbsp;</strong></span></p><h3><strong>Registration</strong></h3><blockquote><p class="cke-user_style-important"><strong>👉</strong><a target="_blank" rel="noopener noreferrer" href="https://cssc2026.spektroskopie.cz/registration_online"><strong>Online registration form</strong></a></p></blockquote><h4><strong>Registration Fees</strong></h4><h5><strong>Early (before June 15, 2026)</strong></h5><ul><li><strong>Participant (Member of IMMSS and SSS): </strong>10 000 CZK&nbsp;&nbsp;</li><li><strong>Participant (Non-member of IMMSS and SSS): </strong>14 000 CZK&nbsp;&nbsp;&nbsp;</li><li><strong>Students: </strong>7 000 CZK&nbsp;</li><li><strong>1-day registration:</strong> 5 000 CZK</li><li><strong>Accompanying person*: </strong>5 000 CZK</li></ul><h5><strong>Regular (after June 15, 2026)</strong></h5><ul><li><strong>Participant (Member of IMMSS and SSS): </strong>13 000 CZK&nbsp;&nbsp;</li><li><strong>Participant (Non-member of IMMSS and SSS): </strong>18 200 CZK&nbsp;&nbsp;&nbsp;</li><li><strong>Students: </strong>9 100 CZK&nbsp;</li><li><strong>1-day registration:</strong> 6 500 CZK</li><li><strong>Accompanying person*: </strong>6 500 CZK</li></ul><p><i>* The accompanying person does not have access to the scientific programme</i></p><p><strong>The conference fee is calculated with VAT</strong> and includes:</p><ul><li>attendance to lectures and poster session</li><li>book of abstracts (electronic version)</li><li>booklet</li><li>lunches, refreshments (coffee/tea breaks)</li><li>excursion</li><li>attendance at Welcome Party and Gala Dinner.&nbsp;</li></ul><p><strong>For an accompanying person</strong>, the conference fee includes the Welcome Party, the excursion and the Conference Dinner. The Conference Dinner is not included in the 1-day registration. This payment should be arranged with the Organising Committee.</p><p><i><strong>Accommodation is not included in the conference fee.</strong></i></p><h3><strong>Abstract submission</strong></h3><blockquote><p class="cke-user_style-important"><strong>👉</strong><a target="_blank" rel="noopener noreferrer" href="https://cssc2026.spektroskopie.cz/abstract_submission_online"><i><strong>ABSTRACT SUBMISSION FORM</strong></i></a></p><p><strong>Deadline</strong> for lecture/poster abstract submission <strong>is June 15, 2026</strong></p></blockquote><h4><strong>Posters</strong></h4><p>Prepare your poster in<strong> English in the format A0</strong> vertically orientated (portrait). The presence of one of the authors at the poster is requested during the poster session. Materials for mounting posters will be available on the poster panels.</p><h4><strong>Lectures</strong></h4><p>Prepare your <strong>presentation in English</strong> in <strong>PowerPoint</strong> of Portable Document Format (<strong>pdf</strong>), both in format <strong>16:9</strong> (widescreen). <strong>Invited and oral lectures</strong> takes <strong>30</strong> and<strong> 20 minutes </strong>(including discussion), respectively.&nbsp;</p><h3><strong>TOPICS &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;&nbsp;</strong></h3><h4><strong>Czech - Slovak Spectroscopic Conference</strong></h4><ul><li>Atomic spectrometry (AAS, ICP-MS, AFS, OES, speciation analysis, etc.)</li><li>Molecular spectrometry/spectroscopy (UV-Vis, NMR, IR, Raman, circular dichroism, etc.)</li><li>New techniques and data processing methods in IR and Raman spectroscopy, Special methods of Raman spectroscopy (resonance Raman, SERS, SERRS, TERS)</li><li>XRF spectrometry (EDS, WDS, XRF, PIXE, etc.)</li><li>Mass spectrometry &amp; hyphenated techniques</li><li>Instrumental radioanalytical methods (Gamma spectroscopy, NAA, etc.)</li><li>Laser spectroscopy and special spectroscopy techniques</li><li>Sample preparation and introduction techniques</li><li>Applications &nbsp;of atomic and molecular spectroscopy</li><li>Statistics and metrology in spectroscopy</li></ul><h4><strong>Mössbauer Spectroscopy in Material Science</strong></h4><ul><li>Environmental, catalytic, biologic, medical applications</li><li>Magnetism, magnetic nanoparticles, molecular magnets</li><li>Nanomaterials, nanostructures, nanocomposites, core-shell nanoparticles, thin films</li><li>Nanomaterials in biomedicine</li><li>Nuclear forward scattering in materials science</li><li>Solid-state chemistry and physics</li><li>Industrial applications, corrosion</li><li>Instrumentation, software</li><li>Earth Science, Mineralogy and Archaeology</li></ul><h4><strong>Venue</strong></h4><h5><strong>Faculty of Science</strong></h5><ul><li>Palacky University Olomouc</li><li>17. listopadu 1192/12, &nbsp;Olomouc, Czech Republic</li></ul>

19th CSSC 2026: Early Bird Registration and Abstract Submission Deadline Approaching

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Ioannes Marcus Marci Spectroscopic Society is a voluntary organization of scientific, scientific-pedagogical and professional workers in the field of spectroscopy, or legal entities engaged in scientific and application activities in this field, associated with joint activities. SSJMM was founded in 1949.

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Phenomenex Biozen SEC-3 LC columns

High inertness and particle consistency of both Biozen™ SEC columns drives greater reproducibility from injection-to-injection. 

<p><strong>High inertness and particle consistency </strong>of both Biozen™ SEC columns drives greater reproducibility from injection-to-injection. Combine this with the bioinert <strong>BioTi hardware</strong> and good aggregate recovery is no longer something that you’re missing out on.</p><p><strong>Biozen SEC columns provide:</strong></p><ul><li>High efficiency on both HPLC and UHPLC</li><li>Extreme inertness and robustness</li><li>Finely tuned high and low MS separation windows</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Biozen_SEC_3_3a6e232271.webp" alt="Phenomenex: Biozen SEC-3" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Biozen_SEC_3_3a6e232271.webp 245w," sizes="100vw" width="500" height="150"></p><ul><li><strong>Separation Mode:</strong> Gel Filtration Chromatography (GFC)</li><li><strong>Particle Size:</strong> 1.8</li><li><strong>Recommended Use:</strong> High molecular weight (HMW) separation range of 10 k – 700 kDa</li></ul><h3><strong>Phenomenex Biozen Biologics LC Columns</strong></h3><p>With a new titanium <strong>BioTi™</strong> biocompatible <strong>hardware</strong> to minimize priming, <strong>four particle platforms</strong> for optimal versatility and <strong>nine particle chemistries</strong> to maximize selectivity and sensitivity, Biozen UHPLC/HPLC columns for <strong>protein analysis</strong> are seamlessly designed to bring peace of mind to your analysis of biologics through:</p><ul><li>Charge Variant Analysis</li><li>Aggregate Analysis</li><li>Peptide Mapping</li><li>Intact Mass Analysis</li><li>Intact and Subunit Analysis</li><li>Glycan Analysis</li><li>Peptide Quantitation</li><li>Drug Antibody Ratio (DAR)</li><li>Oligonucleotide Characterization</li></ul><h3><strong>Biocompatible Flow Path with BioTi™ Hardware</strong></h3><p>Keep your mind at ease knowing that we’ve minimized the need for priming with a new titanium infused biocompatible hardware and frit that doesn’t interfere with protein or peptide integrity!</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Bio_Ti_Hardware_991fb53395.jpg" alt="Phenomenex: BioTi Hardware" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Bio_Ti_Hardware_991fb53395.jpg 245w," sizes="100vw" width="1378" height="426"></p><h3><strong>4 Advanced Particle Platforms</strong></h3><p>All four of the Biozen particle platforms were individually designed and built by Phenomenex to take advantage of integral levels of performance, ruggedness, and reproducibility for protein characterization applications. Individually, each platform differs in the proprietary processing techniques used to control particle size and morphology.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Advanced_Particle_Platforms_a0959aca03.jpg" alt="Phenomenex: Advanced Particle Platforms" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Advanced_Particle_Platforms_a0959aca03.jpg 245w," sizes="100vw" width="1439" height="868"></p>

Phenomenex Biozen SEC-2 LC columns

Biozen SEC columns are extremely inert, high density fully porous particle with high efficiency and low molecular weight separation range.

<p><strong>Biozen SEC columns</strong> are extremely inert, high density fully porous particle with high efficiency and low molecular weight (LMW) <strong>separation range</strong> of <strong>1 k – 450 kDa</strong>.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Biozen_SEC_3_3a6e232271.webp" alt="Phenomenex: Biozen SEC-2" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Biozen_SEC_3_3a6e232271.webp 245w," sizes="100vw" width="500" height="150"></p><ul><li><strong>Separation Mode:</strong> Gel Filtration Chromatography (GFC)</li><li><strong>Particle Size:</strong> 1.8</li><li><strong>Recommended Use:</strong> Low molecular weight (LMW) separation range of 1 k – 450 kDa</li></ul><h3><strong>Phenomenex Biozen Biologics LC Columns</strong></h3><p>With a new titanium <strong>BioTi™</strong> biocompatible <strong>hardware</strong> to minimize priming, <strong>four particle platforms</strong> for optimal versatility and <strong>nine particle chemistries</strong> to maximize selectivity and sensitivity, Biozen UHPLC/HPLC columns for <strong>protein analysis</strong> are seamlessly designed to bring peace of mind to your analysis of biologics through:</p><ul><li>Charge Variant Analysis</li><li>Aggregate Analysis</li><li>Peptide Mapping</li><li>Intact Mass Analysis</li><li>Intact and Subunit Analysis</li><li>Glycan Analysis</li><li>Peptide Quantitation</li><li>Drug Antibody Ratio (DAR)</li><li>Oligonucleotide Characterization</li></ul><h3><strong>Biocompatible Flow Path with BioTi™ Hardware</strong></h3><p>Keep your mind at ease knowing that we’ve minimized the need for priming with a new titanium infused biocompatible hardware and frit that doesn’t interfere with protein or peptide integrity!</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Bio_Ti_Hardware_991fb53395.jpg" alt="Phenomenex: BioTi Hardware" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Bio_Ti_Hardware_991fb53395.jpg 245w," sizes="100vw" width="1378" height="426"></p><h3><strong>4 Advanced Particle Platforms</strong></h3><p>All four of the Biozen particle platforms were individually designed and built by Phenomenex to take advantage of integral levels of performance, ruggedness, and reproducibility for protein characterization applications. Individually, each platform differs in the proprietary processing techniques used to control particle size and morphology.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Advanced_Particle_Platforms_a0959aca03.jpg" alt="Phenomenex: Advanced Particle Platforms" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Advanced_Particle_Platforms_a0959aca03.jpg 245w," sizes="100vw" width="1439" height="868"></p>

Phenomenex Biozen dSEC-2 LC columns

Biozen dSEC columns use low-pore silica with a proprietary hydrophilic diol bond to prevent silica-protein interactions.

<p><strong>Advanced SEC Silica Particle Technology and Surface Chemistry for Characterizing Biomolecules</strong></p><p>The <strong>Biozen dSEC columns</strong> are packed with low pore volume silica coupled with a proprietary hydrophilic diol-type bonded surface chemistry that prevents the silica surface from interacting with <strong>protein samples</strong>.</p><ul><li>Exceptionally Robust, Pore Controlled SEC Particle</li><li>Extreme Stability and Exceptional Lifetime</li><li>Reproducible Separations</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Biozen_dsec_63af9af237.webp" alt="Phenomenex: Biozen-dSEC-2" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Biozen_dsec_63af9af237.webp 245w," sizes="100vw" width="500" height="150"></p><ul><li><strong>Separation Mode:</strong> Gel Filtration Chromatography (GFC)</li><li><strong>Pore size</strong>: 200</li><li><strong>Particle Size:</strong> 1.8, 3</li><li><strong>Recommended Use:</strong> Analysis of monoclonal antibodies, biosimilars and other biomolecules by using specific molecular weights with improved column lifetimes and recovery</li></ul><h4><strong>Biozen SEC Proprietary Silica Particle Technology</strong></h4><p>The Biozen dSEC columns are packed with low pore volume silica coupled with a proprietary hydrophilic diol-type bonded surface chemistry that prevents the silica surface from interacting with protein samples.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Biozen_SEC_Proprietary_Silica_Particle_Technology_502218b910.jpg" alt="Phenomenex: Biozen SEC Proprietary Silica Particle Technology" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Biozen_SEC_Proprietary_Silica_Particle_Technology_502218b910.jpg 245w," sizes="100vw" width="1448" height="469"></p><h4><strong>Improved Column Lifetime and Performance Stability</strong></h4><p>Phenomenex’s optimized SEC column loading technology has significantly improved the overall packing density and silica distribution of the columns leading to improved chromatographic lifetime and stability.</p><h4><strong>New Standard for Platform SEC Methods</strong></h4><p>Whether IgG2 or IgG4 isotypes, bispecifics, or Fc-Fusions, dSEC-2 provides excellent separation and sample recovery for many different classes of antibodies and related recombinant proteins.</p><h3><strong>Phenomenex Biozen Biologics LC Columns</strong></h3><p>With a new titanium <strong>BioTi™</strong> biocompatible <strong>hardware</strong> to minimize priming, <strong>four particle platforms</strong> for optimal versatility and <strong>nine particle chemistries</strong> to maximize selectivity and sensitivity, Biozen UHPLC/HPLC columns for <strong>protein analysis</strong> are seamlessly designed to bring peace of mind to your analysis of biologics through:</p><ul><li>Charge Variant Analysis</li><li>Aggregate Analysis</li><li>Peptide Mapping</li><li>Intact Mass Analysis</li><li>Intact and Subunit Analysis</li><li>Glycan Analysis</li><li>Peptide Quantitation</li><li>Drug Antibody Ratio (DAR)</li><li>Oligonucleotide Characterization</li></ul><h3><strong>Biocompatible Flow Path with BioTi™ Hardware</strong></h3><p>Keep your mind at ease knowing that we’ve minimized the need for priming with a new titanium infused biocompatible hardware and frit that doesn’t interfere with protein or peptide integrity!</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Bio_Ti_Hardware_991fb53395.jpg" alt="Phenomenex: BioTi Hardware" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Bio_Ti_Hardware_991fb53395.jpg 245w," sizes="100vw" width="1378" height="426"></p><h3><strong>4 Advanced Particle Platforms</strong></h3><p>All four of the Biozen particle platforms were individually designed and built by Phenomenex to take advantage of integral levels of performance, ruggedness, and reproducibility for protein characterization applications. Individually, each platform differs in the proprietary processing techniques used to control particle size and morphology.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Advanced_Particle_Platforms_a0959aca03.jpg" alt="Phenomenex: Advanced Particle Platforms" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Advanced_Particle_Platforms_a0959aca03.jpg 245w," sizes="100vw" width="1439" height="868"></p>

Phenomenex Biozen dSEC-7 LC columns

dSEC-7 optimizes dimensions to save sample, speed up runs, and enhance resolution for AAVs and large biomolecule separations.

<p><strong>AAV and Large Biomolecule Aggregate Analysis​</strong></p><p><strong>Biozen dSEC-7 columns</strong> are packed with <strong>700 Å large pore silica</strong> coupled with a proprietary hydrophilic diol-type bonded surface chemistry that ensures silica surface interactions are mitigated. Designed with optimized column dimensions, dSEC-7 conserves valuable sample consumption, facilitates faster run times, and maximizes resolution for AAVs and large biomolecule separations.</p><p><strong>Robust and reliable aggregate analysis:</strong></p><ul><li>Baseline resolution of monomer/aggregate species through 700 Å pore size</li><li>Reduction in sample consumption by up to 90 % compared to traditional SEC columns</li><li>Reduction in method times by up to 50 % when compared to traditional SEC columns</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Biozen_dsec_63af9af237.webp" alt="Phenomenex: Biozen-dSEC-7" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Biozen_dsec_63af9af237.webp 245w," sizes="100vw" width="500" height="150"></p><ul><li><strong>Separation Mode:</strong> Gel Filtration Chromatography (GFC)</li><li><strong>Pore size</strong>: 700</li><li><strong>Recommended Use:</strong> Aggregate analysis of AAVs and other large biomolecules using specific molecular weights that conserves sample consumption, facilitates faster run times, and maximizes resolution.</li></ul><h4><strong>An SEC Column for AAV Aggregate Analysis</strong></h4><figure class="image"><img style="aspect-ratio:668/575;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Biozen_d_SEC_7_Column_b307c4217d.jpg" alt="Phenomenex: Biozen dSEC-7 Column" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Biozen_d_SEC_7_Column_b307c4217d.jpg 182w," sizes="100vw" width="668" height="575"></figure><h4><strong>Biozen dSEC-7 Features</strong></h4><h5><strong>Improved Loading</strong></h5><ul><li>dSEC-7 addresses the challenge of aggregate analysis by offering accurate detection and separation with injections as low as 0.5 µL. Unlike traditional methods that demand large sample volumes, dSEC-7 conserves valuable samples, allowing for replicate analyses and ensuring availability for other CQA tests.</li></ul><h5><strong>Mobile Phase Flexibility</strong></h5><ul><li>dSEC-7’s particle properties facilitate robust separation of monomer from aggregate species, regardless of which mobile phase best suits your sample. This ensures reproducible results while accommodating unique sample demands, easing the burden of method condition optimization during development.</li></ul><h5><strong>Serotype Versatility</strong></h5><ul><li>With its robust performance and 700 Å pore size, dSEC-7 effectively resolves monomer from aggregate peaks across various AAV serotypes. This capability is crucial for evaluating appropriate serotype candidates, each varying in its unique tissue and cell tropisms, to ensure desired therapeutic outcomes are achieved.</li></ul><h5><strong>Instrument Agnostic Performance</strong></h5><ul><li>Despite differences in dwell volume and dispersion across various sites and departments, dSEC-7 consistently delivers robust and reproducible performance across commercially available LC instrumentation. This ensures reliable results regardless of variations in equipment, setup, or location.</li></ul><h5><strong>Outperforms Trending Solutions</strong></h5><ul><li>dSEC-7 excels in providing superior resolution over market alternatives, particularly when characterizing higher-level aggregates in AAV analysis. Unlike current market solutions with insufficient particle pore size, dSEC-7 ensures accurate and reproducible separation of AAV monomer from aggregates.</li></ul><h5><strong>Enhanced Detector Flexibility</strong></h5><ul><li>Conquer sample limitations using SEC-FLR for heightened sensitivity, SEC-MALS for precise molecular weight determination, or SEC-UV for routine analysis. Achieving comprehensive AAV characterization insights by transferring methods across detector technologies with unique benefits is now seamless.</li></ul><h3><strong>Phenomenex Biozen Biologics LC Columns</strong></h3><p>With a new titanium <strong>BioTi™</strong> biocompatible <strong>hardware</strong> to minimize priming, <strong>four particle platforms</strong> for optimal versatility and <strong>nine particle chemistries</strong> to maximize selectivity and sensitivity, Biozen UHPLC/HPLC columns for <strong>protein analysis</strong> are seamlessly designed to bring peace of mind to your analysis of biologics through:</p><ul><li>Charge Variant Analysis</li><li>Aggregate Analysis</li><li>Peptide Mapping</li><li>Intact Mass Analysis</li><li>Intact and Subunit Analysis</li><li>Glycan Analysis</li><li>Peptide Quantitation</li><li>Drug Antibody Ratio (DAR)</li><li>Oligonucleotide Characterization</li></ul><h3><strong>Biocompatible Flow Path with BioTi™ Hardware</strong></h3><p>Keep your mind at ease knowing that we’ve minimized the need for priming with a new titanium infused biocompatible hardware and frit that doesn’t interfere with protein or peptide integrity!</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Bio_Ti_Hardware_991fb53395.jpg" alt="Phenomenex: BioTi Hardware" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Bio_Ti_Hardware_991fb53395.jpg 245w," sizes="100vw" width="1378" height="426"></p><h3><strong>4 Advanced Particle Platforms</strong></h3><p>All four of the Biozen particle platforms were individually designed and built by Phenomenex to take advantage of integral levels of performance, ruggedness, and reproducibility for protein characterization applications. Individually, each platform differs in the proprietary processing techniques used to control particle size and morphology.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Advanced_Particle_Platforms_a0959aca03.jpg" alt="Phenomenex: Advanced Particle Platforms" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Advanced_Particle_Platforms_a0959aca03.jpg 245w," sizes="100vw" width="1439" height="868"></p>

Phenomenex Biozen dSEC-1 LC columns

Phenomenex Biozen dSEC-1 is a high-resolution SEC column for peptide therapeutics, delivering fast, reproducible aggregate analysis with improved peak shape and compatibility with SEC-MS and SEC-MALS.

<h4><strong>High-Resolution Aggregate Analysis for Peptide Therapeutics</strong></h4><p>Biozen dSEC-1 columns are engineered to meet the growing demand for aggregate analysis in peptide therapeutics and mid-sized biologics. Packed with 90 Å small pore silica and featuring inert diol-based surface chemistry, dSEC-1 delivers enhanced resolution for low and high molecular weight peptide aggregates. Its robust design ensures reproducibility and compatibility with advanced workflows like SEC-MS and SEC-MALS.</p><h5><strong>Robust Performance for Peptide Aggregate Analysis</strong></h5><ul><li>High resolution for low/high MW peptide aggregates (1–50 kDa)</li><li>Reproducible, and fast analysis with extended column lifetime</li><li>Improved peak asymmetry by up to 40%</li><li><strong>Recommended Use: </strong>Analysis of peptides, protein fragments, and small biologics with reduced analysis times and improved column lifetimes.</li></ul><h4><strong>Aggregate and Monomer Separation in Liraglutide Formulations</strong></h4><ul><li>Baseline resolution of monomer and two aggregates achieved in under 10 minutes</li><li>Exceptional reproducibility with retention time RSD ≤ 0.08% and peak area RSD ≤ 0.01%</li><li>Clear detection at low levels with S/N ratios of 13, 75, and 10,917 for aggregates and monomer</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_separation_in_liraglutide_formulations_3_b0d97cd01f.jpg" alt="Phenomenex: Aggregate and Monomer Separation in Liraglutide Formulations" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_separation_in_liraglutide_formulations_3_b0d97cd01f.jpg 245w," sizes="100vw" width="938" height="307"></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_separation_in_liraglutide_formulations_2_035bfea3bc.jpg" alt="Phenomenex: Aggregate and Monomer Separation in Liraglutide Formulations" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_separation_in_liraglutide_formulations_2_035bfea3bc.jpg 245w," sizes="100vw" width="1700" height="1050"></p><h3><strong>Biozen SEC Proprietary Silica Particle Technology</strong></h3><p>The Biozen dSEC columns are packed with low pore volume silica coupled with a proprietary hydrophilic diol-type bonded surface chemistry that prevents the silica surface from interacting with protein samples.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Biozen_SEC_Proprietary_Silica_Particle_Technology_502218b910.jpg" alt="Phenomenex: Biozen SEC Proprietary Silica Particle Technology" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Biozen_SEC_Proprietary_Silica_Particle_Technology_502218b910.jpg 245w," sizes="100vw" width="1448" height="469"></p><h4><strong>Improved Column Lifetime and Performance Stability</strong></h4><p>Phenomenex’s optimized SEC column loading technology has significantly improved the overall packing density and silica distribution of the columns leading to improved chromatographic lifetime and stability.</p><h4><strong>New Standard for Platform SEC Methods</strong></h4><p>Whether IgG2 or IgG4 isotypes, bispecifics, or Fc-Fusions, dSEC-2 provides excellent separation and sample recovery for many different classes of antibodies and related recombinant proteins.</p><h3><strong>Phenomenex Biozen Biologics LC Columns</strong></h3><p>With a new titanium <strong>BioTi™</strong> biocompatible <strong>hardware</strong> to minimize priming, <strong>four particle platforms</strong> for optimal versatility and <strong>nine particle chemistries</strong> to maximize selectivity and sensitivity, Biozen UHPLC/HPLC columns for <strong>protein analysis</strong> are seamlessly designed to bring peace of mind to your analysis of biologics through:</p><ul><li>Charge Variant Analysis</li><li>Aggregate Analysis</li><li>Peptide Mapping</li><li>Intact Mass Analysis</li><li>Intact and Subunit Analysis</li><li>Glycan Analysis</li><li>Peptide Quantitation</li><li>Drug Antibody Ratio (DAR)</li><li>Oligonucleotide Characterization</li></ul><h3><strong>Biocompatible Flow Path with BioTi™ Hardware</strong></h3><p>Keep your mind at ease knowing that we’ve minimized the need for priming with a new titanium infused biocompatible hardware and frit that doesn’t interfere with protein or peptide integrity!</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Bio_Ti_Hardware_991fb53395.jpg" alt="Phenomenex: BioTi Hardware" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Bio_Ti_Hardware_991fb53395.jpg 245w," sizes="100vw" width="1378" height="426"></p><h3><strong>4 Advanced Particle Platforms</strong></h3><p>All four of the Biozen particle platforms were individually designed and built by Phenomenex to take advantage of integral levels of performance, ruggedness, and reproducibility for protein characterization applications. Individually, each platform differs in the proprietary processing techniques used to control particle size and morphology.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Advanced_Particle_Platforms_a0959aca03.jpg" alt="Phenomenex: Advanced Particle Platforms" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Advanced_Particle_Platforms_a0959aca03.jpg 245w," sizes="100vw" width="1439" height="868"></p>

Products from category GPC/SEC HPLC columns focused on LC columns from Phenomenex - page 1

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