News from LabRulezLCMS Library - Week 14, 2026

<h3>We're excited to announce that <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/999">Clarity Chromatography Software</a> version 10.1.2 is now available!</h3>This minor update expands Clarity’s portfolio with new control modules.<h4>Newly added Instrument control modules</h4><ul><li>Ecom auxiliary modules</li><li>HTA ICF control modules</li><li>Spark pump</li></ul><h4>Updated Instrument control modules</h4><ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/168">Ecom</a> HPLC</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/328">Knauer</a> HPLC</li><li>Spark ICF control modules</li><li>YoungIn Chromass HPLC</li></ul><blockquote>For a complete list of module changes, see the <a target="_blank" rel="noopener noreferrer" href="https://www.dataapex.com/version_history?product=1">Changelog</a>. For more info about exciting new features directly in Clarity, explore what was introduced in the <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/article/5622">Clarity 10.1 release highlights</a>.Clarity can control 1000+ instruments; the <a target="_blank" rel="noopener noreferrer" href="https://www.dataapex.com/controls">list can be previewed here</a>.</blockquote><h4>Supported Instruments in Clarity (DataApex) — Quick Guide</h4>Clarity Chromatography Software supports a wide range of chromatographs and peripherals via digital control (DD) and analog acquisition (A/D) using the Colibrick module.<h5>Gas Chromatographs (GC)</h5>Digital integration over LAN/RS232 (many via ICF):<ul><li>Agilent: 5890, 6890, 7890, 8860, 8890, Intuvo 9000</li><li>Shimadzu: GC-2010/2014, Nexis GC-2030</li><li>Thermo Fisher: TRACE 1300/1310</li><li>PerkinElmer: Clarus 400–690</li><li>Also supported: Dani, Ellutia, Young In Chromass, Apix, Fuli, GOW-MAC (selected models)</li></ul><blockquote>Note: Most Agilent 6890–8890 and Intuvo use LAN – ICF.</blockquote><h5>HPLC Systems</h5>Full system/module control:<ul><li>Agilent 1100–1290 Infinity II (ICF)</li><li>Shimadzu LC-10/20 and Nexera LC-40</li><li>PerkinElmer Flexar / NexSAR</li><li>Knauer Azura / BlueShadow / Smartline</li><li>Hitachi Chromaster / Primaide</li><li>Young In Chromass ChroZen series</li><li>Sykam S500–S600, Watrex Streamline, Hanon LC7000–7300</li></ul><h5>HPLC Modules (Pumps, Detectors, Ovens, Fraction Collectors)</h5><ul><li>Pumps: Agilent 1100–1290 families, Knauer, Shimadzu, PerkinElmer, Sykam, SSI, Ecom</li><li>Detectors: VWD/DAD(PDA)/RID/FLD/ELSD across Agilent, Shimadzu, Knauer, PerkinElmer, Young In Chromass, Ecom, etc.</li><li>Column Ovens: Agilent G1316x / G7116x, Shimadzu CTO-20/30/40, Knauer CT2.1, PerkinElmer Flexar</li><li>Fraction Collectors: Knauer FC 6.1, Teledyne FOXY series, Ecom ECF 2096, Waters Fraction Collector II</li></ul><h5>Autosamplers</h5><ul><li>Agilent GC ALS (7673/7683/7693/8697), HPLC ALS modules (G1313A–G7167C)</li><li>Shimadzu AOC-20 / AOC-5000+, SIL-10 / SIL-20 / SIL-40 series</li><li>CTC Analytics PAL, HTA autosamplers, Spark Alias/UHPLC, Knauer AS 6.1L</li><li>PerkinElmer Flexar / NexSAR AS</li></ul><h5>Other Devices</h5><ul><li>GC×GC modulators (e.g., Charles University GC×GC Modulator)</li><li>Valves &amp; switch modules (Agilent, Knauer, Shimadzu, VICI-Valco)</li><li>Degassers, flow monitors, managers, interfaces</li><li>LC-MS / GC-MS: Advion Expression CMS, Microsaic 4500 MiD, Markes BenchTOF (and others)</li><li>Balances (EA extension): Mettler Toledo, Sartorius</li></ul><h5>Analog Acquisition (Colibrick)</h5>A/D support for legacy or analog-output devices:<ul><li>GC: Agilent 5880/4890A, Varian 3xxx/3800/3900, PerkinElmer Clarus series, Thermo TRACE, Shimadzu GC-14/9A, Scion 43x/45x/83xx/85xx, etc.</li><li>HPLC Detectors: Waters 2487/2489, ESA Corona, Hitachi L-series, JASCO FP/UV, Ecom LCD series, many others</li><li>Elemental &amp; Amino Acid Analyzers: Carlo Erba/Costech ECS, Biochrom 20/30+</li></ul>If you are interested in a DEMO VERSION, contact us!

DataApex Clarity Chromatography software 10.1.2 just released!

🎤Dan Reddy (PhD candidate in the Department of Chemistry at Queen's University and a recipient of the NSERC Vanier Canada Graduate Scholarship. He was recently named one of the top 35 early-career scientists globally in the 2025 CAS Future Leaders program.)In this episode, we interview Daniel Reddy, 2025 CAS Future Leader and PhD candidate at Queen's University, about his groundbreaking research on automated mass spectrometry and dried matrix spots (DMS).Dan's work combines computer vision, 3D printer automation, and laser micromachining to revolutionize sample preparation—reducing CO₂ emissions by 28-fold and organic solvent use by 21-fold compared to traditional methods.<h4>What You'll Learn:</h4><ul><li>How to give a mass spectrometer "sight" and "taste" using computer vision and the LMJ-SSP (Liquid Microjunction Surface Sampling Probe)</li><li>The breakthrough technology behind Surface Energy Traps (SETs) for confining liquid droplets on paper substrates</li><li>Why dried matrix spots eliminate the need for cold-chain shipping and enable analysis of blood, urine, and saliva samples via standard mail</li><li>How DIY chemists are hacking 3D printers to build cost-effective autosamplers (replacing $10K+ systems)</li><li>The role of green chemistry and systems thinking in modernizing analytical methods</li><li>Why interdisciplinary collaboration (chemistry + computer science) is critical to innovation</li></ul><h4>Key Topics:</h4><ul><li>Dried Matrix Spots (DMS) for automated sample prep</li><li>Laser-micromachined Surface Energy Traps</li><li>Direct surface sampling mass spectrometry</li><li>Sustainability in analytical chemistry</li><li>3D printer customization for laboratory automation</li><li>The importance of science communication and community outreach</li></ul><h3>Video Transcription</h3><h4>Introduction</h4>Recent advances in analytical chemistry increasingly focus on simplifying workflows, improving sustainability, and enabling automation. In this context, the work of Dan Reddy centers on the concept of “bringing mass spectrometry to life” through the integration of automated sampling, computer vision, and dried matrix spot (DMS) methodologies.The primary objective is to enable efficient and reproducible analysis of biological and liquid samples—such as blood, urine, saliva, or other solutions—by depositing them onto substrates, drying them, and extracting meaningful analytical information directly via mass spectrometry.<h4>Conceptual Framework: Enabling “Sight” and “Taste” in Mass Spectrometry</h4>A central innovation in this work is the conceptual transformation of mass spectrometry from a passive analytical tool into an active, semi-autonomous system.<ul><li>“Sight” is introduced through camera-based computer vision, allowing the system to identify predefined patterns on a substrate.</li><li>“Taste” is implemented via a liquid microjunction surface sampling probe (LMJSSP), which enables direct extraction of analytes from surfaces.</li></ul>The LMJSSP consists of two concentric capillaries forming a continuously flowing microdroplet. When brought into contact with the sample surface, this droplet facilitates localized extraction, effectively enabling direct surface analysis without traditional chromatographic separation.Combined with an automated positioning system (adapted from 3D printer mechanics), the platform can autonomously locate sampling sites and perform reproducible measurements.<h4>Dried Matrix Spots as an Analytical Platform</h4><h5>Principle and Advantages</h5>Dried matrix spots involve depositing a small volume of liquid sample onto a substrate (commonly paper), followed by drying. This approach offers several advantages:<ul><li>Reduced need for cold-chain transport</li><li>Simplified sample handling and storage</li><li>Compatibility with remote or decentralized sampling</li><li>Lower solvent consumption</li></ul>These features contribute significantly to greener analytical workflows and improved logistical efficiency.<h5>Sustainability Impact</h5>The implementation of DMS-based workflows has demonstrated:<ul><li>Up to 28-fold reduction in CO₂ emissions</li><li>Up to 21-fold reduction in organic solvent use</li></ul>These improvements arise from eliminating cold-chain logistics and minimizing solvent-intensive preparation steps.<h4>Surface Energy Traps (SCTs): Controlled Micro-Sampling Environments</h4><h5>Definition and Fabrication</h5>Surface Energy Traps (SCTs) are microstructured regions on a substrate designed to confine liquid droplets within defined boundaries.The fabrication process involves:<ol><li>Coating paper with a hydrophobic layer</li><li>Using laser ablation to selectively remove the coating in defined patterns</li><li>Creating hydrophilic circular regions (typically ~0.5 mm diameter)</li></ol>These patterned regions act as micro-wells that confine droplets spatially and prevent lateral diffusion.<h5>Analytical Benefits</h5>SCTs address key limitations of traditional dried matrix spots:<ul><li>Improved spatial confinement of analytes</li><li>Reduced diffusion variability</li><li>Enhanced reproducibility</li><li>Preconcentration effects due to controlled drying</li></ul>Additionally, the SCT diameter is smaller than the sampling probe, enabling near-complete analyte collection during surface extraction.<h4>Drying Dynamics and Analyte Distribution</h4>Traditional dried matrix spots often suffer from the “coffee-ring effect”, where analytes redistribute unevenly during drying. This leads to variability depending on sampling location.The SCT approach mitigates these effects by:<ul><li>Limiting diffusion area</li><li>Maintaining analytes near the surface</li><li>Producing more uniform analyte distribution</li></ul>Preliminary investigations (e.g., via SEM imaging) indicate improved homogeneity, although further studies are needed to fully characterize drying kinetics and their influence on signal intensity.<h4>Integration with Automated Sampling Systems</h4><h5>3D Printer-Based Positioning</h5>A key engineering innovation is the repurposing of 3D printer hardware for automated sample positioning:<ul><li>Provides cost-effective XYZ motion control</li><li>Enables programmable sampling routines</li><li>Supports integration with analytical instrumentation</li></ul>Custom software—developed in collaboration with computer engineers—allows users to define coordinates, dwell times, and sampling parameters.<h5>Computer Vision Integration</h5>The addition of computer vision enables:<ul><li>Pattern recognition (e.g., alignment markers near SCTs)</li><li>Autonomous targeting of sampling locations</li><li>Reduced operator intervention</li></ul>This transforms the system into a semi-autonomous analytical platform.<h4>Comparison with Conventional Workflows</h4>Compared to traditional LC-MS or GC-MS workflows, the presented approach offers:<div><div><figure class="table"><table><thead><tr><th>Aspect</th><th>Conventional Methods</th><th>SCT + LMJSSP Approach</th></tr></thead><tbody><tr><td>Sample prep</td><td>Multi-step, solvent-intensive</td><td>Minimal, direct surface sampling</td></tr><tr><td>Chromatography</td><td>Required</td><td>Potentially bypassed</td></tr><tr><td>Throughput</td><td>Moderate</td><td>High (automated)</td></tr><tr><td>Sustainability</td><td>Limited</td><td>Significantly improved</td></tr></tbody></table></figure></div></div>While chromatographic methods remain essential for many applications, this approach provides a complementary pathway for rapid screening and targeted analyses.<h4>Green Chemistry and Systems Thinking</h4>A notable aspect of this work is the integration of systems thinking into analytical chemistry. Inspired by engagement with organizations such as the American Chemical Society and green chemistry initiatives, the research emphasizes:<ul><li>Environmental impact reduction</li><li>Resource efficiency</li><li>Lifecycle considerations</li></ul>This perspective expands the role of analytical chemists beyond method performance to broader societal and environmental implications.<h4>Future Outlook and Applications</h4>The research is currently at an early stage but shows strong potential for:<ul><li>Decentralized diagnostics (e.g., remote blood sampling)</li><li>Environmental monitoring</li><li>High-throughput screening workflows</li><li>Field-deployable analytical systems</li></ul>Further advancements are expected in:<ul><li>Substrate engineering</li><li>Automation robustness</li><li>Integration with advanced MS platforms (e.g., triple quadrupole systems)</li></ul><h4>Conclusion</h4>The integration of dried matrix spots, surface energy traps, and automated surface sampling represents a significant step toward more sustainable, efficient, and accessible analytical workflows.By combining innovations in microfabrication, computer vision, and mass spectrometry, the work of Dan Reddy demonstrates how analytical chemistry can evolve toward smarter, greener, and more autonomous systems.<blockquote>This text has been automatically transcribed from a video presentation using AI technology. It may contain inaccuracies and is not guaranteed to be 100% correct.</blockquote><blockquote><h4>Concentrating on Chromatography Podcast</h4>Dive into the frontiers of chromatography, mass spectrometry, and sample preparation with host David Oliva. Each episode features candid conversations with leading researchers, industry innovators, and passionate scientists who are shaping the future of analytical chemistry. From decoding PFAS detection challenges to exploring the latest in AI-assisted liquid chromatography, this show uncovers practical workflows, sustainability breakthroughs, and the real-world impact of separation science. Whether you’re a chromatographer, lab professional, or researcher you'll discover inspiring content!You can find Concentrating on Chromatography Podcast in podcast apps:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://open.spotify.com/show/1wZg67rCjoGju4yhqxI3tL">Spotify</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podcasts.apple.com/tz/podcast/concentrating-on-chromatography/id1788429185">Apple podcast</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podscan.fm/podcasts/concentrating-on-chromatography">podscan</a></li></ul>and on <a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/@ChromatographyTalk/videos">YouTube channel</a></blockquote>

Mass Spectrometry, Surface Sampling and Dried Matrix Spots - Greener Chemistry and 3D Printing

Article

Product

Application

Video

Scientists

Interview

Science and research

Software

Since 1991 DataApex develops and manufactures chromatography data stations. DataApex is constantly striving to provide users with efficient and up-to-date tools for chromatography data processing.

DataApex

Everything from the world of analytical chemistry in one place. We connect people in solving their problems. At Labrulez you will find all the necessary information easily, quickly and clearly. Stop searching and start finding.

LabRulez

Organomation, founded in 1959, designs and manufactures high-quality nitrogen evaporators and extraction systems. Known for innovation and durability, their lab instruments are used globally for efficient sample preparation with strong customer support.

Organomation

ECOM ECP201LG Gradient Preparative Pump 1000 mL/min

An innovative, powerful, and cost-effective unit for preparative LC separations with high pressure. 4 low pressure gradient valves, flow up to 1000 mL/min. 

<div style="display:block;" aria-labelledby="tab_item-0">The ECP201L Preparative Pump is an innovative, powerful, and cost-effective unit for preparative liquid chromatography where high pressure is needed. The pump with 4 low-pressure valves delivers a flow rate of up to 1000 mL/min at a very high output pressure of up to 15 MPa (2176 psi).<h3>Main features and benefits</h3><h4>Durability</h4>The pump is constructed for high pressure and flow rates. This makes it suitable for day-to-day long-term use in production<h4>Wide application possibilities</h4>The unit is used for pharmaceutical separations and plant extract purification, such as cannabinoids, peptides, and oligonucleotides. Also, it has much wider use in other chemical production, such as dosing into chemical reactors, and in various laboratory uses. Another advantage is the usability of the same device for separation method development.<h4>Smart controls and diagnostics</h4>It is easy to operate, especially with ECOMAC and Clarity software. This makes unit management powerful and convenient. The basic version of the ECOMAC software is available free of charge. It is also used for service and diagnostics.<h4>Other useful features</h4><ul><li>A new learning algorithm for pulsation suppression</li><li>A leakage sensor</li><li>A seal wash kit for longer piston seal life</li><li>Also available in configurations made of certified bio-inert materials</li></ul><h3>Parameters</h3><ul><li>Flow rate: 1 – 1000 ml/min</li><li>Maximum operating pressure in the pump: 15 MPa up to 1000 ml/min</li><li>Flow rate setting: 1 ml/min steps</li><li>Repeatability of flow rate adjusting: ± 1 %</li><li>Accuracy of flow rate setting: ± 2 %</li><li>Wetted materials in the pump: stainless steel, PEEK, TefzelTM, Kalrez®, ceramic, seals GFP (PTFE) by default or UHMW-PE on request</li><li>Control: RS232, Ethernet(LAN), USB</li><li>Output capillary outer diameter: 1/8 "</li><li>Input tubing outer diameter: 3/8 ”</li><li>Number of gradient valves*: 4 (A,B,C,D)</li><li>Orifice: 5 mm</li><li>Fluid temperature: 5 - 90°C</li><li>Connecting thread: 5/8" - 18 UNF</li><li>Power supply: 100 - 240 V AC</li><li>Power input: 500 VA</li><li>Weight of the complete set: 30 kg (66.14 lb)</li><li>Dimensions (w x h x d) of the complete set: 340 x 170 x 640 mm (13.4 x 6.7 x 25.2 in)</li></ul></div>

ECP2050 Preparative Pump

Preparative HPLC pump with flow-rate ranges of 0.001 to 50 ml/min. 

<div style="display:block;" aria-labelledby="tab_item-0">This pump works as an isocratic pump and together with a gradient box also as a gradient pump.These powerful and durable pumps are suitable for preparative applications in low- and high-pressure liquid chromatography across the chemical industry. They are designed with 2 pump heads connected in parallel with a piston diameter of 3/8”.Many improvements make these pumps more reliable, including a new learning algorithm for pulsation suppression and a leakage sensor. The pumps can operate in two modes, i.e. using constant pressure or the newly added option of constant flow rate. New material versions have been added-in beyond to stainless steel A316L, also Hastelloy, titanium and PEEK for biocompatible applications.<h4>Gradient function</h4>These pumps work as isocratic pumps, and, together with ECOM gradient boxes, they also work as gradient pumps. Gradient boxes ECB2007, ECB2007PC are equipped with a four-way gradient mixing valve and must be ordered together with the pump. These sophisticated units allow for achieving a precise low-pressure gradient, i.e. gradual changes of solvent composition by mixing up to four liquids at the pump‘s entry. The gradient profile can be defined via a computer or manually using a display and a keypad. Without the use of a gradient box, the pump works as isocratic, with the option of one solvent and the composition of the mobile phase being chosen by the user.Customers can use the pistons‘ back-washing function, after working, for example, with a buffered mobile phase.<h4>Seals</h4>All pumps are delivered with GFP (PTFE) seals by default. You can order the pumps with UHMW-PE seals, which are considered the optimal recommended choice.<h4>Software support</h4>The pumps are supported by ECOMAC and Clarity software.<h3>Main features and benefits</h3><ul><li>All models include a display and keyboard for manual control</li><li>&nbsp;Precise low-pressure gradient mixing (when connected with a gradient module)</li><li>Very good durability and reliability with proper maintenance</li><li>Extended number of wetted material versions – not only stainless steel but also Hastelloy, titanium and PEEK for biocompatible applications</li><li>Piston back-washing function for work with buffered or aggressive mobile phases</li><li>New learning algorithm for pulsation suppression</li><li>Integrated leakage sensor</li><li>Heating unit for pump heads available</li><li>Custom pump modifications of request</li></ul>This pump is equipped with the Pressure Compensation Learning algorithm. Thanks to this smart adaptive process, the pump regulates the rotation speed of the camshaft and measures its impact on pressure pulsation to minimize the output pulsation as much as possible. The algorithm, due to its adaptive capacity, is applicable for many combinations of pump working conditions (solvents, columns, etc.).<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ECOM_ECP_2200_Preparative_Pump_5_b84832f1e8.jpg" alt="ECOM: ECP2050 - Preparative Pump - Pressure Compensation Learning algorithm " srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ECOM_ECP_2200_Preparative_Pump_5_b84832f1e8.jpg 188w," sizes="100vw" width="700" height="580"><h3>Optional configurations/variants</h3>Pump head heating unit, see the accessories shown below. In case you would like this function for your pump, add also the heating unit to&nbsp;your cart. (Also can be found in the Accessories product category).<h5>PN / Wetted parts of pumping block</h5><ul><li>ACCH000X / Hastelloy</li><li>ACCP000X /<span style="-webkit-text-stroke-width:0px;display:inline !important;float:none;font-style:normal;font-variant-caps:normal;font-variant-ligatures:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:start;text-decoration-color:initial;text-decoration-style:initial;text-decoration-thickness:initial;text-indent:0px;text-transform:none;white-space:normal;widows:2;word-spacing:0px;"> PEEK</li><li>ACC0000X / Stainless steel</li><li>ACCT000X / Titanium</li></ul><h4>Parameters:</h4><ul><li>Flow rate: 0.001 – 50 ml/min</li><li>Maximum operating pressure: 30 MPa (4351 psi)</li><li>Flow rate setting: 0.1 ml/min steps</li><li>Repeatability of flow rate adjusting: ± 0,5 %</li><li>Accuracy of flow rate setting: ± 2 %</li><li>Wetted materials: Stainless steel or Hastelloy or Titanium or PEEK + PEEK, TefzelTM, PE, ceramics, seals&nbsp;</li><li>Communication: RS232, Ethernet (LAN), USB, Remote digital I/O</li><li>Power supply: 100 240V 50/60Hz 250VA</li><li>Dimensions W x H x D: 280 x 135 x 498 mm (11.02 x 5.12 x 18.23 in)</li><li>Weight: 12 kg (26,5 lb)</li><li>Output capillary outer diameter: 1/16”</li><li>Upper pressure limit (MPa): 0,1 – 30 (4351PSI)</li><li>Precision of pressure measurement: ± 2%</li><li>Supported Gradient Box: ECB2005, ECB2005PC</li><li>Pressure Compensation Learning: yes&nbsp;</li></ul></div>

ECOM TOY18DAD 600 H Four Channel UV/PDA Detector

Four Channel version of our detector measures at four wavelengths simultaneously with possibility to see current scan and with built-in lamp working hours counter.

<div style="display:block;" aria-labelledby="tab_item-0">TOY18DAD 600 H Four Channel UV Detector is a standalone UV-VIS detector suited for preparative and flash chromatography with diode array (DAD) in range 200 – 600 nm.Four&nbsp;Channel&nbsp;version measures at&nbsp;four wavelengths simultaneously&nbsp;with possibility to see&nbsp;current scan.More wavelengths or scan are used in liquid chromatography to verify purity of analyzed samples or in situations when some peaks absorb on different wavelengths.<h4>Most important features of TOY18DAD H detectors:</h4><ul><li>built-in lamp working hours counter</li><li>easy replacement of flow cell</li><li>measuring at more wavelengths simultaneously</li><li>sophisticated diagnostic software</li></ul><h4>Parameters:</h4><ul><li>Number of channels (Signals): 4</li><li>Scan: Informative 200 – 600 nm</li><li>Number of CCD elements: 256</li><li>Communication: RS232, Ethernet (LAN), USB</li><li>Accuracy of adjustment: ± 1 nm</li><li>Typical spectral half-width: 10 nm</li><li>Reproducibility: ± 0.5 nm</li><li>Noise (Test cell, 254nm, TC 2s, 10 Hz): ± 5 x 10-5 AU</li><li>Drift (Test cell, 254nm): 1 x 10-3 AU/hr</li><li>Time constant: Time constant (T63) 0.5 s, 0.75 s, 1.0 s, 2.0 s, 4.0 s, 8.0 s, 16.0 s, 0.2 s, 0.1</li><li>Communication: RS232,Ethernet (LAN),USB</li><li>Power supply: 100-240V 50/60Hz</li><li>Power input: 100 VA (120 VA for upcoming version)</li><li>Materials in contact with mobile phase: FEP; fused silica, stainless steel, PEEK, KEL-F</li><li>Optical cables: no</li><li>Dimensions W x H x D: 280 x 135 x 463 mm (11.02 x 5.32 x 18.23 in)</li><li>Weight: 7.5 kg (16.53 lb)</li></ul></div>

ECOM TOY20DAD 800 H Two Channel UV/PDA Detector

Two Channel version of our detector measures at two wavelengths simultaneously with possibility to see current scan and with built-in lamp working hours counter.

<div style="display:block;" aria-labelledby="tab_item-0">TOY20DAD 800 H &nbsp;Channel UV Detector is a standalone UV-VIS detector suited for preparative and flash chromatography with diode array (DAD) in range 190 – 800 nm.Two&nbsp;Channel&nbsp;version measures at&nbsp;two wavelengths simultaneously&nbsp;with possibility to see&nbsp;current scan.More wavelengths or scan are used in liquid chromatography to verify purity of analyzed samples or in situations when some peaks absorb on different wavelengths.<h4>Most important features of TOY20DAD 800H detectors:</h4><ul><li>built-in lamp working hours counter</li><li>easy replacement of flow cell</li><li>measuring at more wavelengths simultaneously</li><li>sophisticated diagnostic software</li></ul><h4>Parameters:</h4><ul><li>Number of channels (Signals): 2</li><li>Scan: Informative 190 – 800 nm</li><li>Number of CCD elements: 256</li><li>Communication: RS232, Ethernet (LAN), USB</li><li>Accuracy of adjustment: ± 1 nm/±0.5 nm</li><li>Typical spectral half-width: 10 nm</li><li>Reproducibility: ± 0.5 nm</li><li>Noise (Test cell, 254nm, TC 2s, 10 Hz): ± 5 x 10-5 AU</li><li>Drift (Test cell, 254nm): 1 x 10-3 AU/hr</li><li>Time constant: 0.5 s, 0.75 s, 1.0 s, 2.0 s, 4.0 s, 8.0 s, 16.0 s, 0.2 s, 0.1 s</li><li>Communication: RS232,Ethernet (LAN),USB</li><li>Power supply: 100-240V; 50 - 60Hz</li><li>Power input: 100 VA (120 VA for upcoming version)</li><li>Materials in contact with mobile phase: FEP; fused silica, stainless steel, PEEK, KEL-F</li><li>Optical cables: no</li><li>Dimensions W x H x D: 280 x 135 x 463 mm (11.02 x 5.32 x 18.23 in)</li><li>Weight: 7.5 kg (16.53 lb)&nbsp;</li></ul></div>

ECOM TOY18DAD 800 H Scanning UV/PDA Detector 

Scanning version of our detector measures at four wavelengths simultaneously or sends scan with speed 20 Hz which allows to create 3D picture.

<div style="display:block;" aria-labelledby="tab_item-0">TOY18DAD 800 H Scanning UV Detector is a standalone UV-VIS detector suited for preparative and flash chromatography with diode array (DAD) in range 200 – 800 nm.Scanning version measures at four wavelengths simultaneously or sends scan with speed 20 Hz which allows to create 3D picture.More wavelengths or scan are used in liquid chromatography to verify purity of analyzed samples or in situations when some peaks absorb on different wavelengths.<h4>Most important features of TOY20DAD 800H detectors:</h4><ul><li>built-in lamp working hours counter</li><li>easy replacement of flow cell</li><li>measuring at more wavelengths simultaneously</li><li>sophisticated diagnostic software</li></ul><h4>Parameters:</h4><ul><li>Number of channels (Signals): 4</li><li>Scan: Informative 200 – 800 nm, 20 Hz, step 1 nm</li><li>Number of CCD elements: 256</li><li>Communication: RS232, Ethernet (LAN), USB</li><li>Accuracy of adjustment: ± 1 nm/±0.5 nm</li><li>Typical spectral half-width: 10 nm</li><li>Reproducibility: ± 0.5 nm</li><li>Noise (Test cell, 254nm, TC 2s, 10 Hz): ± 5 x 10-5 AU</li><li>Drift (Test cell, 254nm): 1 x 10-3 AU/hr</li><li>Time constant: 0.5 s, 0.75 s, 1.0 s, 2.0 s, 4.0 s, 8.0 s, 16.0 s, 0.2 s, 0.1 s</li><li>Communication: RS232,Ethernet (LAN),USB</li><li>Power supply: 100-240V; 50 - 60Hz</li><li>Power input: 100 VA (120 VA for upcoming version)</li><li>Materials in contact with mobile phase: FEP; fused silica, stainless steel, PEEK, KEL-F</li><li>Optical cables: no</li><li>Dimensions W x H x D: 280 x 135 x 463 mm (11.02 x 5.32 x 18.23 in)</li><li>Weight: 7.5 kg (16.53 lb)&nbsp;</li></ul></div>

ECOM TOY18DAD 400 H Scanning UV/PDA Detector 

<div style="display:block;" aria-labelledby="tab_item-0">TOY18DAD 400 H Scanning Channel UV Detector is a standalone UV-VIS detector suited for preparative and flash chromatography with diode array (DAD) in range 200 – 400 nm.Scanning version measures at four wavelengths simultaneously or sends scan with speed 20 Hz which allows to create 3D picture.More wavelengths or scan are used in liquid chromatography to verify purity of analyzed samples or in situations when some peaks absorb on different wavelengths.<h4>Most important features of TOY20DAD 800H detectors:</h4><ul><li>built-in lamp working hours counter</li><li>easy replacement of flow cell</li><li>measuring at more wavelengths simultaneously</li><li>sophisticated diagnostic software</li></ul><h4>Parameters:</h4><ul><li>Number of channels (Signals): 4</li><li>Scan: Informative 200 – 400 nm, 20 Hz, step 1 nm</li><li>Number of CCD elements: 256</li><li>Communication: RS232, Ethernet (LAN), USB</li><li>Accuracy of adjustment: ± 1 nm</li><li>Typical spectral half-width: 8 nm</li><li>Reproducibility: ± 0.5 nm</li><li>Noise (Test cell, 254nm, TC 2s, 10 Hz): ± 5 x 10-5 AU</li><li>Drift (Test cell, 254nm): 1 x 10-3 AU/hr</li><li>Time constant: 0.5 s, 0.75 s, 1.0 s, 2.0 s, 4.0 s, 8.0 s, 16.0 s, 0.2 s, 0.1 s</li><li>Communication: RS232,Ethernet (LAN),USB</li><li>Power supply: 100-240V; 50 - 60Hz</li><li>Power input: 100 VA (120 VA for upcoming version)</li><li>Materials in contact with mobile phase: FEP; fused silica, stainless steel, PEEK, KEL-F</li><li>Optical cables: no</li><li>Dimensions W x H x D: 280 x 135 x 463 mm (11.02 x 5.32 x 18.23 in)</li><li>Weight: 7.5 kg (16.53 lb)&nbsp;</li></ul></div>

ECOM TOY18DAD 800 H Four Channel UV/PDA Detector

<div style="display:block;" aria-labelledby="tab_item-0">TOY18DAD 800 H Four Channel UV Detector is a standalone UV-VIS detector suited for preparative and flash chromatography with diode array (DAD) in range 200 – 800 nm.Four&nbsp;Channel&nbsp;version measures at&nbsp;four wavelengths simultaneously&nbsp;with possibility to see&nbsp;current scan.More wavelengths or scan are used in liquid chromatography to verify purity of analyzed samples or in situations when some peaks absorb on different wavelengths.<h4>Most important features of TOY18DAD H detectors:</h4><ul><li>built-in lamp working hours counter</li><li>easy replacement of flow cell</li><li>measuring at more wavelengths simultaneously</li><li>sophisticated diagnostic software</li></ul><h4>Parameters:</h4><ul><li>Number of channels (Signals): 4</li><li>Scan: Informative 200 – 800 nm</li><li>Number of CCD elements: 256</li><li>Communication: RS232, Ethernet (LAN), USB</li><li>Accuracy of adjustment: ± 1 nm/±0.5 nm</li><li>Typical spectral half-width: 10 nm</li><li>Reproducibility: ± 0.5 nm</li><li>Noise (Test cell, 254nm, TC 2s, 10 Hz): ± 5 x 10-5 AU</li><li>Drift (Test cell, 254nm): 1 x 10-3 AU/hr</li><li>Time constant: Time constant (T63) 0.5 s, 0.75 s, 1.0 s, 2.0 s, 4.0 s, 8.0 s, 16.0 s, 0.2 s, 0.1</li><li>Communication: RS232,Ethernet (LAN),USB</li><li>Power supply: 100-240V 50/60Hz</li><li>Power input: 100 VA (120 VA for upcoming version)</li><li>Materials in contact with mobile phase: FEP; fused silica, stainless steel, PEEK, KEL-F</li><li>Optical cables: no</li><li>Dimensions W x H x D: 280 x 135 x 463 mm (11.02 x 5.32 x 18.23 in)</li><li>Weight: 7.5 kg (16.53 lb)</li></ul></div>

ECOM TOY18DAD 600 VEX Scanning UV/DAD Detector 

Absorbance measuring on four wavelengths simultaneously, an online scan of the whole spectrum with a speed of up to 20 Hz, and with built-in lamp working hours counter.

<div style="display:block;" aria-labelledby="tab_item-0">TOY18DAD 600 VEX Scanning UV Detector is UV-VIS diode array detector, which allows measuring absorbance of four wavelengths simultaneously in external cell connected by optical cables, just as measuring of whole spectrum (scan). More wavelengths or scan are used in liquid chromatography to verify purity of analyzed samples or in situations when some peaks absorb on different wavelengths. It is possible to use the detector in flash and preparative applications.It is possible to control the detector manually by keyboard and display but also using RS232, USB, or LAN. At the back panel are available four analog outputs and a connector for I/O logical input and output signals.<h4>The unit’s DAD (diode array detector) design offers many advantages:</h4><ul><li>absorbance measuring on four wavelengths simultaneously.</li><li>wavelength setting in increments of 1 nm.</li><li>an online scan of the whole spectrum with a speed of up to 20 Hz which allows the creation of a 3D picture.</li><li>lamp work hours are counted using the built-in counter for both deuterium and halogen lamps.</li><li>SMA connectors at the front panel allow easy connection of the external cell.</li><li>powering by 100-240 V AC.</li><li>the unit can be controlled by RS232, USB, LAN or a keyboard.</li><li>signals are available in analog and digital form.</li><li>easy service and diagnostics using display and keyboard or by service SW.</li></ul><h4>Parameters:</h4><ul><li>Number of channels (Signals): 4</li><li>Scan: Informative 200 – 600 nm, 20 Hz, step 1 nm&nbsp;</li><li>Number of CCD elements: 256</li><li>Communication: RS232, Ethernet (LAN), USB</li><li>Accuracy of adjustment: ± 1 nm</li><li>Typical spectral half-width: 10 nm</li><li>Reproducibility: ± 0.5 nm</li><li>Communication: RS232,Ethernet (LAN),USB</li><li>Power supply: 100-240V 50/60Hz</li><li>Power input: 100 VA (120 VA for upcoming version)</li><li>Noise level at empty cell (254 nm, TC 1 s): ± 8 × 10-5 AU&nbsp;</li><li>Drift at empty cell (254 nm after 1 h): 5 × 10-3 AU/hr.&nbsp;</li><li>Dimensions W x H x D: 135 x 170 x 340 mm (5.32 x 6.69 x 13.39 in)&nbsp;</li><li>Weight: 3.8 kg (8.4 lb)</li></ul></div>

ECOM ECDM2100 Conductivity and pH Monitors

ECDM 2100 are conductivity and pH monitors suited for preparative and flash chromatography. The monitor cell had been developed for high-pressure applications and it can be used in CaptureSMB applications.

ECDM 2100 are conductivity and pH monitors suited for preparative and flash chromatography. Thanks to the unique ECOM design of the conductivity cell, it radically improves chromatography process monitoring.The monitor cell had been developed for high-pressure applications, which means it can be used in CaptureSMB applications. These applications utilize a twin-column periodic countercurrent (PCC) process used for the continuous purification of monoclonal antibodies.The unit is controlled by a printed board, which measures the conductivity of liquid passing through both the cell and the pH value.<h4>Main features and benefits</h4><ul><li>High-pressure cell up to 17 MPa (for 1/16” version)</li><li>Simple conductivity calibration</li><li>Compact size</li><li>Powered by 12 – 24 V DC</li><li>Sophisticated diagnostic software</li></ul><h4>Parameters</h4><ul><li>Conductivity Monitoring: 0.01 – 300.0 mS/cm</li><li>Operating pressure: 0 – 17 MPa (0 – 2465.6 psi; 0 – 170.0 bar)</li><li>Communication: RS232, Ethernet (LAN), USB</li><li>Flow rate: Conductivity monitor-0.01 – 200 mL/min</li><li>pH reading ranges: 0.0-14.0 pH</li><li>Wetted materials: Titanium and PEEK (conductivity monitor)</li><li>Communication: RS232,Ethernet (LAN),USB</li><li>Power supply: 12 - 24 V DC</li><li>Power input: 2.5 W</li><li>Cell connecting: Tubing with OD 1/16″, thread UNF 10-32 , tubing with OD 1/8″, thread UNF 1/4-28″</li><li>Dimensions W x H x D: 140 x 168 x 165 mm (5.51” x 6.61” x 6.46”)</li><li>Weight: 1.31 kg (2.89 lb)&nbsp; &nbsp;</li></ul>

ECOM AS96 HPLC Autosampler

A reliable and precise autosampler for a wide range of applications in HPLC and LC-MS with/without cooling and heating, in a compact design. 

A reliable and precise autosampler for a wide range of applications in HPLC and LC-MS with/without cooling and heating, in a compact design.AS96 Autosampler is a generic autosampler using state-of-the-art injection technology with fast injection and wash cycles. Efficient, multi-solvent needle wash virtually eliminates carry-over. AS96 enables excellent reagent addition and mix capabilities for derivatization, dilution, and internal standard addition. Our Pressure Assisted Sample Aspiration (PASA™) concept avoids sample-syringe contact and air bubbles and has proven its robustness in more than 30,000 autosamplers.AS96 Autosampler handles well plates and sample vials, either open or sealed. Its compact, stackable design and unrivaled performance make the AS96 the best fit for any analytical system. The autosampler can also be equipped with a sample cooling module. The Peltier module with forced air cooling provides true sample cooling down to 4 °C in the sample compartment.<h4>Features</h4><ul><li>Metal-free sampling with silica-coated steel needle and PEEK valve (option)</li><li>Reagent addition and mix capabilities for derivatization, dilution, internal standard addition</li><li>Optional 6-port solvent selection valve (SVV) for extended selection of reagents for needle wash and reagent addition (option)</li><li>Integrated Stream Switching (ISS): optional extra high-pressure 6-port switching valve for column switching or other stream switching applications up to 18,000 Psi</li><li>Quick-fit injection valve for fast service</li></ul><h4>Parameters</h4><ul><li>PN: ASA96000</li><li>Injection modes: Full-loop, Partial loop-fill , µL-pick-up</li><li>Injection volume: Programmable from 0 µl – 9999 µL 1 µL increments</li><li>Injection precision: Full-loop injection ‹ 0.3% RSD; Partial loop-fill ‹ 0.5% RSD; µL -pick-up ‹ 1.0% RSD</li><li>Sample viscosity: 0.1 – 5 cP</li><li>Injections per vial/well: Max 9</li><li>Syringe volume: 500 µL standard; 250, 1000 and 2500 µL optional</li><li>Needle wash - Inside and outside needle wash with drying. Wash can be programmed between injections and between vials/wells: 1 solvent, 5 additional wash solvents</li><li>Injection cycle time: 60 seconds</li><li>Valve switching time: 60 msec</li><li>Wetted parts: SS316, PTFE, TEFZEL, VESPEL, glass, For Bio-kit option: PEEK and coated-steel (needle) instead of SS316</li><li>Loop volumes: Programmable from 0 µl – 9999 µL 1 µL increments&nbsp;</li><li>Carry-over: ‹ 0.05% with standard wash, Typically ‹ 0.01% with extra wash</li><li>Sample capacity: Microtiter plates: 2; Vials: 2x 48 (1.5 mL) or 2x 12 (10 mL) - optional</li><li>Maximum vial/MTP height: 47 mm</li><li>Sample cooling - Factory installed option (Peltier technology): Minimum: 4°C ± 2°C Maximum: ambient temp -3°C</li></ul>

Products from category HPLC components from ECOM - page 1

Related content

Mass Spectrometry, Surface Sampling and Dried Matrix Spots - Greener Chemistry and 3D Printing

DataApex Clarity Chromatography software 10.1.2 just released!

News from LabRulezLCMS Library - Week 14, 2026