<h4><strong>Do you use results of chemical analyses as a basis for your decisions and judgements?</strong></h4><p>Those of us working in accredited laboratories or dealing with issues concerning the quality of measurements, would like to inform you about some important changes concerning the way the results of measurements are presented. These changes make it easier for you as an end-user to make correct decisions.</p><h4><strong>Nobody is perfect!</strong></h4><p>Results of analyses cannot be perfect! We hope this does not come as a big surprise to you. We use the term <strong>measurement uncertainty </strong>to describe this lack of perfection.</p><h4><strong>The analytical process</strong></h4><p>In each step of the analytical work, from sampling to the final measurement, deviations from the true value occur and measurement conditions vary. We take measures and perform controls regularly to assure that these deviations and variations together are small enough to make sure the end result fulfils your requirements. When we don’t have full information about all of the steps, e.g. when sampling and initial sample preparation are performed by you as a customer, you can assist us by providing detailed information about how that work was performed. Our experts are ready to advise on all matters regarding sampling. Please contact the laboratory beforehand.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Eurachem_Important_information_to_our_customers_concerning_the_quality_of_measurements_2_d885f6b051.jpg" alt="Eurachem: The analytical process" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Eurachem_Important_information_to_our_customers_concerning_the_quality_of_measurements_2_d885f6b051.jpg 139w," sizes="100vw" width="562" height="630"></p><h4><strong>Results should be fit-for-the-purpose</strong></h4><p>The accuracy of the results must of course not be too low nor too high since this would increase the costs. It should be fit for the intended purpose. If you are unsure on what level of accuracy you need, do not hesitate to contact the laboratory.</p><h4><strong>Uncertainty and limiting values</strong></h4><p>Many analyses are made to assure that limiting values are not exceeded. Without information about the measurement uncertainty it may appear to be very easy to make decisions, but these decision may be incorrect, with, e.g. economical consequences when rejecting instead of accepting a product, judicial consequences when returning a verdict of guilty instead of not guilty, or medical consequences when carrying out an unnecessary treatment. There are numerous examples!</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Eurachem_Important_information_to_our_customers_concerning_the_quality_of_measurements_3_f0ef8edc77.jpg" alt="Eurachem: Uncertainty and limiting values" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Eurachem_Important_information_to_our_customers_concerning_the_quality_of_measurements_3_f0ef8edc77.jpg 245w," sizes="100vw" width="932" height="453"></p><p>With a realistic measurement uncertainty the information included in the result becomes much more useful.</p><h4><strong>It will be easier to compare results</strong></h4><p>Most laboratories have until now chosen not to state measurement uncertainty in the test report. Instead, such information has only been given when the customer has asked for it</p><p>In the future, information about the measurement uncertainty will appear more frequently in the test report. It is also possible that you will bump into new and unfamiliar quality terms. This is due to the fact that there are new international guides and standards describing a common and partly new terminology. One of the objectives is to make it easier for you as a customer to compare test results.</p><h4><strong>What could it look like?</strong></h4><p>When reporting the test result we will give the normal information about what we have measured. When the results are followed by uncertainty statements, they are presented as intervals within which the true values are expected to lie with a certain level of confidence (usually 95%). In the example below the lead content is 1.65 ± 0.15 mmol·kg-1, that is between 1.50 and 1.80. The measurement uncertainty is also often reported relatively, in %.</p><ul><li><strong>Total lead content (Pb): </strong>1.65 mmol·kg<sup>-1</sup>&nbsp;</li><li><strong>Measurement uncertainty:</strong> 0.15 mmol·kg<sup>-1</sup> (9.1%)&nbsp;</li></ul><p>The stated uncertainty is an expanded measurement uncertainty (<i>U</i>). It was obtained by multiplying the combined standard uncertainty <i>u<sub>c</sub></i> with a coverage factor <i>k</i> equal to 2. This corresponds approximately to a 95 % confidence interval.</p><h4><strong>All’s well that ends well...</strong></h4><p>The requirements for a consistent way of reporting test results are increasing. Therefore, those of us involved in measurements are eager to assure ourselves that we understand your needs. You will notice this in your contacts with us before, during and after the test assignment. We hope that you will be satisfied with the final result.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Eurachem_Important_information_to_our_customers_concerning_the_quality_of_measurements_4_f870b1a7b8.jpg" alt="Eurachem: All’s well that ends well..." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Eurachem_Important_information_to_our_customers_concerning_the_quality_of_measurements_4_f870b1a7b8.jpg 159w," sizes="100vw" width="713" height="701"></p>

Important information to our customers concerning the quality of measurements

Modernizing Routine HPLC Methods: Aligning Productivity, Compliance, and Sustainability

<p><strong>Wiley, a global leader in authoritative content and research intelligence for the advancement of scientific discovery, innovation, and learning, today announced the release of the multi-format </strong><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/2461"><i><strong>NIST / EPA / NIH EI Mass Spectral Library 2026</strong></i><strong> </strong></a><strong>and </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/2462"><i><strong>NIST MS/MS Spectral Library 2026</strong></i></a><strong>.</strong></p><p>Developed by the experienced mass spectrometry (MS) team at the National Institute of Standards and Technology (NIST), these databases represent the culmination of more than four decades of comprehensive evaluation and expansion, making it an essential resource for those analyzing mass spectra.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Wiley_NIST_EPA_NIH_EI_Mass_Spectral_Library_2026_af64f091bd.jpg" alt="Wiley: NIST / EPA / NIH EI Mass Spectral Library 2026" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Wiley_NIST_EPA_NIH_EI_Mass_Spectral_Library_2026_af64f091bd.jpg 111w," sizes="100vw" width="1531" height="2159"></p><h4><strong>New in the 2026 release:</strong></h4><ul><li>The <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/2461"><i><strong>NIST/NIH/EPA EI Mass Spectral Library</strong></i></a> includes <strong>35,000+ new compounds</strong>, bringing the total to <strong>431,000+ EI (electron ionization) spectra</strong>, with expanded coverage of biologically, environmentally, and industrially relevant compounds.</li><li>The <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/2462"><i><strong>NIST MS/MS Mass Spectral Library</strong></i></a> now contains <strong>3.2 million+ spectra</strong> across <strong>68,600+ compounds</strong>, spanning metabolites, drugs, pesticides, peptides, lipids, glycans, extractable and leachable compounds, surfactants, and contaminants.</li><li>The<i> <strong>GC Retention Index Library </strong></i>added over <strong>35,000 compounds</strong>, further enhancing compound identification workflows.</li><li>The underlying <strong>NIST MS Search software</strong> has also been extensively updated and now includes chromatogram analysis for GC-MS or LC-MS/MS workflows.</li><li><strong>From 2026, the EI and MS/MS libraries are available as separate products</strong>. Both can be ordered through Wiley, with bundle options available.</li></ul><p>“<i>Wiley distributes NIST EI 2026 in more instrument formats than any other NIST 2026 provider,</i>” said Graeme Whitley, Senior Director, Data Science Solutions at Wiley. “<i>In addition to the standalone NIST libraries, Wiley also offers customers the option to extend their capabilities with the </i><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/887"><i><strong>Wiley Registry</strong> </i></a><i>and </i><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/934"><i><strong>KnowItAll GC-MS</strong></i></a><i><strong> and </strong></i><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1942"><i><strong>LC-MS libraries</strong></i></a><i>, delivering broader coverage and flexibility for evolving analytical workflow needs.</i>”</p><p>The EI library is available in multiple instrumentation manufacturer formats, while the MS/MS library is provided in NIST format. Together, these libraries support high-confidence analysis across GC-MS and LC-MS workflows, helping laboratories confidently improve identification and streamline analytical processes.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Wiley_NIST_MS_MS_Mass_Spectral_Library_2026_899749d679.jpg" alt="Wiley: NIST MS/MS Mass Spectral Library 2026" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Wiley_NIST_MS_MS_Mass_Spectral_Library_2026_899749d679.jpg 110w," sizes="100vw" width="1526" height="2160"></p><h5><strong>Learn more at Wiley Science Solutions:</strong></h5><ul><li>Visit our web for more information about the <a target="_blank" rel="noopener noreferrer" href="https://sciencesolutions.wiley.com/solutions/technique/gc-ms/nist-epa-nih-mass-spectral-library/"><i><strong>NIST/EPA/NIH EI Mass Spectral Library 2026</strong></i></a></li><li>Visit our web for more information about the <a target="_blank" rel="noopener noreferrer" href="https://sciencesolutions.wiley.com/solutions/technique/lc-ms/nist-ms-ms-mass-spectral-library-2026/"><i><strong>NIST MS/MS Mass Spectral Library 2026</strong></i></a></li></ul><h5><strong>About Wiley</strong></h5><p>Wiley is a global leader in authoritative content and research intelligence for the advancement of scientific discovery, innovation, and learning. With more than 200 years at the center of the scholarly ecosystem, Wiley combines trusted publishing heritage with AI-powered platforms to transform how knowledge is discovered, accessed, and applied. From individual researchers and students to Fortune 500 R&amp;D teams, Wiley enables the transformation of scientific breakthroughs into real-world impact. From knowledge to impact—Wiley is redefining what's possible in science and learning.&nbsp;</p>

Wiley Releases NIST Mass Spectral Library 2026 in Multiple Instrument-Ready Formats

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Thermo Scientific™ Dionex™ Easion™ Ion Chromatography System

Compact IC system with built-in suppressor, heated conductivity detection, and automated sample handling—ideal for routine anion and cation analysis in water and environmental labs.

<h4><strong>Compact, intuitive IC system for routine anion and cation analysis</strong></h4><p><strong>The Dionex Easion IC system is a small yet powerful ion chromatography solution designed for routine water and environmental analysis. With its compact footprint, easy setup, and intuitive Chromeleon™ CDS control, the system enables fast, reliable quantification of both anions and cations—even for inexperienced users. Built-in chemical suppression, minimal maintenance, and preconfigured analysis kits make it ideal for any lab performing standard IC workflows.</strong></p><h3><strong>Key Features and Benefits</strong></h3><h4>🧪 <strong>Simple, Complete System</strong></h4><ul><li>Fully integrated setup includes suppressor, columns, eluent and regenerant concentrates</li><li>Ready to operate in under <strong>90 minutes</strong>—no extra pumps or accessories needed</li><li>Compatible with 2, 3, and 4 mm anion and cation columns</li></ul><h4>📏 <strong>Reliable, Reproducible Performance</strong></h4><ul><li><strong>Heated bipolar conductivity cell</strong> ensures signal stability and low noise</li><li>Chemical suppression with <strong>Dionex CRS 500</strong> suppressor—no regeneration steps needed</li><li>Fixed-loop valve for <strong>manual or automated injections</strong></li><li>Flow range: 0.01–5.00 mL/min; pressure up to 5000 psi</li></ul><h4>💡 <strong>Smart and Compact Design</strong></h4><ul><li>All-PEEK flow path—metal-free and chemically inert</li><li>Simple eluent preparation with concentrates and high-purity water</li><li>Bench-friendly size (33 × 24 × 40 cm, 10 kg) with minimal maintenance</li></ul><h4>🔁 <strong>Automation Ready</strong></h4><ul><li>Supports <strong>Dionex AS-DV, AS-AP, and AS-HV autosamplers</strong></li><li>Built-in sample filtration (with AS-DV) and dilution workflows</li><li>Autosampler-based inline filtration and degassing options available</li></ul><h4>🧠 <strong>Controlled by</strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/76"><strong> Chromeleon™ CDS</strong></a></h4><ul><li>Intuitive system setup with ProcedureWizards™ and application templates</li><li>Built-in calibration memory and audit trail</li><li>Virtual column simulator and multi-vendor instrument integration</li></ul><h3><strong>Applications</strong></h3><ul><li><strong>Drinking water</strong> and <strong>wastewater</strong> monitoring</li><li><strong>Inorganic ion analysis</strong> (F⁻, Cl⁻, NO₃⁻, PO₄³⁻, SO₄²⁻, etc.)</li><li><strong>Routine ammonium and cation detection</strong> (Li⁺, Na⁺, NH₄⁺, Ca²⁺...)</li><li><strong>Educational and QA/QC laboratories</strong></li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Dionex_Easion_System_news_1f1d3e6c64/Thermo-Dionex-Easion-System-news.jpg" alt="Thermo Scientific™ Dionex™ Easion™ Ion Chromatography System" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Dionex_Easion_System_news_1f1d3e6c64/thumbnail_Thermo-Dionex-Easion-System-news.jpg 215w," sizes="100vw" width="1103" height="800"></p>

Thermo Scientific™ Dionex™ ICS-4000 Capillary HPIC™ System

Capillary HPIC system for high-resolution, reagent-free ion chromatography with 24/7 readiness, ultra-low eluent use, and versatile detection in a compact format.

<h4><strong>Always on, always ready — high-resolution capillary IC in a compact platform</strong></h4><p>The <strong>Dionex ICS-4000</strong> is the world’s first <strong>dedicated capillary high-pressure reagent-free ion chromatography (HPIC) system</strong>. Designed for high-resolution, low-flow separations, it delivers exceptional chromatographic performance, fast analysis times, and 24/7 on-demand readiness. With integrated control, capillary-optimized detectors, and minimal eluent consumption, it offers a new standard for reliable, low-maintenance ion chromatography.</p><h3><strong>Key Features and Benefits</strong></h3><h4>🧪 <strong>Capillary HPIC Performance</strong></h4><ul><li>Supports <strong>high-pressure separations</strong> with 4 µm columns</li><li><strong>Fast, high-resolution gradients</strong> in minutes</li><li>Continuous operation with <strong>no equilibration needed</strong></li></ul><h4>♻️ <strong>Reagent-Free Simplicity</strong></h4><ul><li><strong>Eluent generation</strong> from deionized water via EGC cartridge</li><li>Just <strong>15 mL of water/day</strong> for continuous operation</li><li>Eluent cartridges last up to <strong>18 months</strong></li></ul><h4>🧠 <strong>Integrated Smart Design</strong></h4><ul><li>Fully integrated system in <strong>compact footprint</strong></li><li><strong>Tilt-up lid</strong>, color-coded connections, and pre-cut tubing</li><li><strong>Vacuum degassing</strong>, seal wash (option), and inline shut-off valves</li></ul><h4>🧲 <strong>Versatile Detection Options</strong></h4><ul><li><strong>Conductivity Detector (CD)</strong> – with self-regenerating suppressor</li><li><strong>Electrochemical Detector (ED)</strong> – ideal for cyanide, amines, carbohydrates</li><li><strong>QD Charge Detector</strong> – signal proportional to ion charge and concentration</li></ul><h4>🔁 <strong>Flexible Column Chemistry</strong></h4><ul><li>Compatible with <strong>over 20 capillary columns</strong></li><li>Suitable for a wide range of inorganic and organic ions, sugars, acids, amines</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Dionex_ICS_4000_Iontovy_Chromatograf_2_64107dbdca/Thermo-Dionex-ICS-4000-Iontovy-Chromatograf-2.jpg" alt="Thermo Scientific™ Dionex™ ICS-4000 Capillary HPIC™ System" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Dionex_ICS_4000_Iontovy_Chromatograf_2_64107dbdca/thumbnail_Thermo-Dionex-ICS-4000-Iontovy-Chromatograf-2.jpg 156w," sizes="100vw" width="650" height="650"></p><h3><strong>Automation and Sample Handling</strong></h3><ul><li>Compatible with <strong>Dionex AS-DV</strong> and <strong>AS-AP</strong> autosamplers</li><li>Advanced prep (dilution, derivatization, matrix removal)</li><li>Supports <strong>vials, well plates</strong>, and &lt;30 s injection cycles</li><li>Optional <strong>Sample Conductivity &amp; pH Accessory</strong> with conditional logic</li></ul><h3><strong>Software Integration</strong></h3><ul><li>Controlled by <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/76"><strong>Chromeleon™ Chromatography Data System (CDS)</strong></a></li><li>eWorkflows™ simplify analysis from injection to report</li><li>Interactive charts and MiniPlots for intuitive data interpretation</li></ul><h3><strong>Ideal for Applications in</strong></h3><ul><li>Food and beverage (e.g., sugars, organic acids, preservatives)</li><li>Environmental (e.g., drinking water, wastewater)</li><li>Pharmaceutical (e.g., excipients, counterions)</li><li>Educational and routine analytical labs</li></ul>

Thermo Scientific™ Orbitrap Fusion™ Tribrid™ Mass Spectrometer

Orbitrap Fusion Tribrid MS combines quadrupole, ion trap, and Orbitrap analyzers for ultra-flexible MSⁿ workflows, enabling deep proteomics, PTM analysis, and confident structural elucidation.

<h4><strong>Revolutionary tribrid architecture for comprehensive structural analysis and deep proteome coverage</strong></h4><p>The Orbitrap Fusion Tribrid mass spectrometer combines a quadrupole, a linear ion trap, and an Orbitrap mass analyzer in a unique architecture that delivers unmatched analytical performance. It provides life scientists with advanced MS<sup>n</sup> capabilities, flexibility in fragmentation techniques, and exceptional resolution and speed — ideal for tackling the most complex analytical challenges in proteomics, PTMs, metabolomics, lipidomics, and small molecule research.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_Thermo_Orbitrap_Fusion_Tribrid_hmotnostni_spektrometr_e93c577ae5/Pragolab-Thermo-Orbitrap-Fusion-Tribrid-hmotnostni-spektrometr.webp" alt="Thermo Scientific™ Orbitrap Fusion™ Tribrid™ Mass Spectrometer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Pragolab_Thermo_Orbitrap_Fusion_Tribrid_hmotnostni_spektrometr_e93c577ae5/thumbnail_Pragolab-Thermo-Orbitrap-Fusion-Tribrid-hmotnostni-spektrometr.webp 245w," sizes="100vw" width="1914" height="1059"></p><h3><strong>Key Features and Benefits</strong></h3><h4>🔬 <strong>Revolutionary Tribrid Design</strong></h4><ul><li>Combines <strong>quadrupole</strong>, <strong>linear ion trap</strong>, and <strong>Orbitrap</strong> analyzers</li><li>Perform <strong>MSⁿ up to n = 10</strong> with detection in either ion trap or Orbitrap</li><li>Fragmentation options: <strong>CID</strong>, <strong>HCD</strong>, <strong>ETD</strong>, and <strong>EThcD</strong> at any MS stage</li><li><strong>Synchronous Precursor Selection (SPS)</strong>: up to <strong>20 precursors per scan</strong> for MS³</li></ul><h4>⚙️ <strong>High Performance &amp; Resolution</strong></h4><ul><li><strong>Resolving power up to 500,000 FWHM</strong> at m/z 200</li><li><strong>&lt;1 ppm</strong> mass accuracy with EASY-IC™ internal calibration</li><li><strong>Polarity switching in 1.1 s full cycle</strong></li><li><strong>Scan speeds up to 20 Hz</strong> for Orbitrap and ion trap MSn</li></ul><h4>🧪 <strong>Versatility in Applications</strong></h4><ul><li>Analyze <strong>low-abundance</strong>, <strong>high-complexity</strong>, or structurally complex samples</li><li>Confidently resolve <strong>isobaric interferences</strong> and detect <strong>PTMs</strong></li><li>Full compatibility with <strong>intact protein analysis</strong>, glycoproteomics, and TMT SPS-MS³ quantitation workflows</li></ul><h4>🔁 <strong>Efficient Ion Handling</strong></h4><ul><li><strong>EASY-Max NG</strong> or <strong>NanoSpray Flex NG</strong> ion sources</li><li><strong>Active Beam Guide</strong> and <strong>S-Lens</strong> for efficient ion transmission</li><li><strong>Dynamic Scan Management</strong> optimizes scan scheduling and parallelization</li></ul><h4>💡 <strong>Ease of Use</strong></h4><ul><li>Intuitive <strong>Tune and Method Editors</strong></li><li>Method templates for routine and advanced workflows</li><li><strong>Quanfirmation</strong>: HRAM SIM for quantitation + ion trap MS/MS for confirmation</li><li>Automated calibration, AGC, and exclusion logic</li></ul><h4>🧬 <strong>Compatible Software</strong></h4><ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1758"><strong>Xcalibur™</strong></a><strong>, </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1782"><strong>Proteome Discoverer™</strong></a><strong>, </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1756"><strong>ProSight™</strong></a><strong>, </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1757"><strong>Mass Frontier™</strong></a><strong>, </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1759"><strong>Compound Discoverer™</strong></a>, and others</li><li>Support for data-dependent, targeted, and deconvolution workflows</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_Thermo_Orbitrap_Fusion_Tribrid_hmotnostni_spektrometr_2_3d7accb56e/Pragolab-Thermo-Orbitrap-Fusion-Tribrid-hmotnostni-spektrometr-2.webp" alt="Thermo Scientific™ Orbitrap Fusion™ Tribrid™ Mass Spectrometer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Pragolab_Thermo_Orbitrap_Fusion_Tribrid_hmotnostni_spektrometr_2_3d7accb56e/thumbnail_Pragolab-Thermo-Orbitrap-Fusion-Tribrid-hmotnostni-spektrometr-2.webp 245w," sizes="100vw" width="1038" height="622"></p>

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Modernizing Routine HPLC Methods: Aligning Productivity, Compliance, and Sustainability

Wiley Releases NIST Mass Spectral Library 2026 in Multiple Instrument-Ready Formats

Important information to our customers concerning the quality of measurements