Thermo Scientific™ Dionex™ ICS-4000 Capillary HPIC™ System

Always on, always ready — high-resolution capillary IC in a compact platform

The Dionex ICS-4000 is the world’s first dedicated capillary high-pressure reagent-free ion chromatography (HPIC) system. Designed for high-resolution, low-flow separations, it delivers exceptional chromatographic performance, fast analysis times, and 24/7 on-demand readiness. With integrated control, capillary-optimized detectors, and minimal eluent consumption, it offers a new standard for reliable, low-maintenance ion chromatography.

Key Features and Benefits

🧪 Capillary HPIC Performance

• Supports high-pressure separations with 4 µm columns
• Fast, high-resolution gradients in minutes
• Continuous operation with no equilibration needed

♻️ Reagent-Free Simplicity

• Eluent generation from deionized water via EGC cartridge
• Just 15 mL of water/day for continuous operation
• Eluent cartridges last up to 18 months

🧠 Integrated Smart Design

• Fully integrated system in compact footprint
• Tilt-up lid, color-coded connections, and pre-cut tubing
• Vacuum degassing, seal wash (option), and inline shut-off valves

🧲 Versatile Detection Options

• Conductivity Detector (CD) – with self-regenerating suppressor
• Electrochemical Detector (ED) – ideal for cyanide, amines, carbohydrates
• QD Charge Detector – signal proportional to ion charge and concentration

🔁 Flexible Column Chemistry

• Compatible with over 20 capillary columns
• Suitable for a wide range of inorganic and organic ions, sugars, acids, amines

Thermo Scientific™ Dionex™ ICS-4000 Capillary HPIC™ System

Automation and Sample Handling

• Compatible with Dionex AS-DV and AS-AP autosamplers
• Advanced prep (dilution, derivatization, matrix removal)
• Supports vials, well plates, and <30 s injection cycles
• Optional Sample Conductivity & pH Accessory with conditional logic

Software Integration

• Controlled by Chromeleon™ Chromatography Data System (CDS)
• eWorkflows™ simplify analysis from injection to report
• Interactive charts and MiniPlots for intuitive data interpretation

Ideal for Applications in

• Food and beverage (e.g., sugars, organic acids, preservatives)
• Environmental (e.g., drinking water, wastewater)
• Pharmaceutical (e.g., excipients, counterions)
• Educational and routine analytical labs