<h3>A Dedicated Solution for Oligonucleotide Analysis</h3>Oligonucleotides have become key players in modern pharmaceutical and biological research, particularly in the development of highly targeted and personalized therapies. As increasing numbers of oligonucleotide-based drugs enter clinical trials or receive regulatory approval, analytical laboratories face growing demands for both throughput and data quality. These molecules present unique chromatographic challenges due to their long, highly polar structures and subtle variations in nucleobase sequence or functionalization.<h3>Sepapure oliGO – Designed for Oligonucleotide Separations</h3>Selecting the optimal chromatographic approach for oligonucleotide analysis can be complex. Many laboratories rely on ion-pair reversed-phase (IP-RP) chromatography because of its speed, robustness, and compatibility with mass spectrometry. However, commonly used ion-pair reagents can degrade conventional silica-based stationary phases.<a target="_blank" rel="noopener noreferrer" href="https://www.knauer.net/columns-oligonucleotide-columns">Sepapure oliGO</a> addresses this limitation through a hybrid silica matrix combined with specialized surface end-capping, ensuring resistance to aggressive IP-RP reagents. Its functionalized surface enables both strong reversed-phase interactions and controlled ionic contributions, effectively creating a mixed-mode separation mechanism. This design results in improved durability compared with standard mixed-mode columns, making Sepapure oliGO a robust choice for routine oligonucleotide workflows.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_Figure_1_Sepapure_oli_GO_columns_with_laser_etched_column_information_23f545be81.jpg" alt="KNAUER: Figure 1 - Sepapure oliGO columns with laser-etched column information." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_Figure_1_Sepapure_oli_GO_columns_with_laser_etched_column_information_23f545be81.jpg 223w," sizes="100vw" width="1186" height="828"><h3>Method Transfer and Comparative Performance</h3>In collaboration with BianoGMP GmbH, KNAUER’s application team evaluated Sepapure oliGO against a widely used reference column. The study compared oligonucleotides of varying lengths and purities, including a fully thiolated 43-mer DNA. Particular attention was paid to potential interactions between thiolated oligonucleotides and stainless-steel hardware, which have been reported to cause peak tailing.The results demonstrated that direct method transfer between the reference column and Sepapure oliGO was generally feasible without significant adjustment. Chromatographic resolution remained comparable, while retention times were slightly shorter on Sepapure oliGO. Furthermore, the anticipated benefits of expensive bioinert hardware were not confirmed under the tested conditions, suggesting that such effects may primarily influence very fast (U)HPLC separations.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_Figure_2_Overlayed_chromatogram_of_crude_product_of_a_43mer_thiolate_oligonucleotide_7ae9613efd.jpg" alt="KNAUER: Figure 2: Overlayed chromatogram of crude product of a 43mer thiolate oligonucleotide. Light blue - reference column and dark blue – Sepapure oliGO." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_Figure_2_Overlayed_chromatogram_of_crude_product_of_a_43mer_thiolate_oligonucleotide_7ae9613efd.jpg 245w," sizes="100vw" width="1223" height="453"><h3>Low Backpressure for Reliable Operation</h3>Sepapure oliGO can be applied effectively in both HPLC and (U)HPLC workflows. Its low operating backpressure minimizes risks associated with clogging, excessive system wear, and performance deterioration over time. Typical IP-RP separations using 3 µm particles generated pressures around 200 bar, enabling laboratories without ultra-high-pressure systems to perform high-quality oligonucleotide analysis.<h3>Best Practices for Column Performance</h3>To maintain optimal performance, users should observe recommended operating conditions, including a broad pH range of 1.5–10 and temperatures up to 60 °C. Employing a guard column can prevent coarse synthesis by-products from reaching the analytical column. If pressure increases are observed, backflushing at low flow rates can restore performance.When the system is idle, thorough flushing to remove salts is essential. For storage, the column should be kept in a 1:1 mixture of methanol–water or acetonitrile–water. Gradient transitions are recommended when switching between standard RP eluents and IP-RP reagents. Regeneration procedures developed for RP columns are also suitable for Sepapure oliGO.<h3>Beyond Analytical Separations</h3>For large-scale purification, ion-exchange chromatography (AEX) may offer advantages. Scalable preparative systems are available to support purification workflows, ranging from compact laboratory setups to pilot-scale platforms with flow rates up to 800 mL/min. Bioinert configurations can be integrated where required, allowing laboratories to tailor purification solutions to their specific oligonucleotide applications.<blockquote><ul><li>If you're planning to set up or optimize your oligonucleotide workflow, feel free to contact us at sales@knauer.net. Stay tuned for more exciting insights into the Oligonucleotide world in our “Oligos Made Easy” series.</li><li>For more in-depth discussion or questions, reach out to the author at folmert@knauer.net&nbsp;</li></ul></blockquote>

Oligos Made Easy - Part 8: Sepapure oliGO

Visit the LabRulez booth at <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/events/871">analytica 2026</a> in Munich, 24. - 27. March 2026! You can find us in Hall A1, Booth A1.506. At the booth, you will be able to explore live demonstrations of how the LabRulez portals work and see selected analytical instruments from our pre-owned marketplace section.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Lab_Rulez_at_Analytica_2026_Floor_plan_55e1057e03.jpg" alt="LabRulez at Analytica 2026: Hall A1 Floor Plan and Booth Location" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Lab_Rulez_at_Analytica_2026_Floor_plan_55e1057e03.jpg 245w," sizes="100vw" width="1516" height="881"><h3>Would you like to learn how the LabRulez portals work?</h3>➡︎ <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/">LabRulezLCMS</a> ➡︎ <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/">LabRulezGCMS</a> ➡︎ <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/">LabRulezICPMS</a><ul><li>A unique online solution for your marketing</li><li>A targeted audience from the analytical chemistry community</li><li>Modern technologies and a unique concept</li><li>Design optimized for most smart devices – PC, mobile, and tablet</li><li>Advanced statistical tools fully available to users</li></ul><h3>Services Offered</h3><h4>News + Company Updates</h4><ul><li>Publish news related to your instrumentation, applications, services, events, job openings, and more</li><li>News is shared both on our portals and across our social media channels</li></ul><h4>Library – All Documents in One Place</h4><ul><li>Applications, posters, presentations, technical articles, brochures, specifications</li><li>Fast and advanced search capabilities</li><li>Over 32,000 documents currently available in our database</li></ul><h4>Webinars</h4><ul><li>Upcoming and on-demand webinars from the field of analytical chemistry</li><li>More than 5,500 webinars covering chromatography, mass spectrometry, and spectroscopy</li></ul><h4>Careers</h4><ul><li>Targeted job listings in analytical chemistry</li><li>Clear filtering by specialization or location</li><li>Increased visibility for job postings</li></ul><h4>Companies</h4><ul><li>Company profile with key information and contacts</li><li>Integration of all your activities on our portal: News, Library documents, Webinars, Upcoming Events, Careers, and mentions by partners or customers</li><li>Connection to your Products listed on LabRulez portals</li></ul><h4>Products and Services</h4><ul><li>Comprehensive overview of instrumental techniques and services</li><li>Targeting the analytical chemistry community and customers in the growing online environment</li></ul><h4>Marketplace</h4><ul><li>Buying and selling pre-owned analytical equipment</li><li>We purchase analytical instrumentation of all brands and ages</li><li>Sell your equipment through LabRulez</li><li>Request and purchase complete systems, modules, or spare parts with warranty and service</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Lab_Rulez_at_analytica_2026_bazar_7edf4a0872.jpg" alt="LabRulez at analytica 2026" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Lab_Rulez_at_analytica_2026_bazar_7edf4a0872.jpg 88w," sizes="100vw" width="1600" height="2844"><h3>What Will Be on Display at Our Booth?</h3>Come and explore selected spare parts and modules from our marketplace section. These include both new, tested, and pre-owned items.<h4><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/bazaar">LabRulezLCMS Marketplace</a></h4>Spare parts for LC/MS:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/bazaar?category=378">Vacuum turbo pumps for LC/MS</a></li></ul>Spare parts for HPLC:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/bazaar?category=397">Degassers for HPLC/UHPLC</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/bazaar?category=368&amp;search=valve">Automatic valves for HPLC</a></li><li>HPLC components for Agilent 1100, 1200, and 1260 Infinity II series</li></ul>Consumables:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/bazaar?category=377">HPLC lamps</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/bazaar?category=48">HPLC columns</a></li></ul><h4><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar">LabRulezGCMS Marketplace</a></h4>Spare parts for GC/MS:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar?category=367&amp;search=turbo">Turbo pumps for GC/MS</a></li></ul>Spare parts for GC:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar?category=366&amp;search=EPC">EPC modules</a></li></ul>Sample injection<ul><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar/432">Autosampler 7693A for GC</a></li></ul>Consumables:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar?category=7">GC columns </a>and selected accessories</li></ul>

LabRulez at analytica 2026

News from LabRulezLCMS Library - Week 13, 2026

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Everything from the world of analytical chemistry in one place. We connect people in solving their problems. At Labrulez you will find all the necessary information easily, quickly and clearly. Stop searching and start finding.

LabRulez

Based in Berlin, KNAUER is a medium-sized, owner-managed company that has been serving the sciences since 1962. We develop and manufacture scientific instruments of superior quality for liquid chromatography, including: Analytical HPLC/UHPLC, Preparative HPLC, Fast protein liquid chromatography (FPLC), Multi-column chromatography/Simulated moving bed (SMB) chromatography. High pressure dosing, in-line detection systems, and osmometry are additional business areas.

KNAUER

New Food magazine

Metrohm

Agilent Technologies

Thermo Fisher Scientific

This webinar hosted by Select Science together with Metrohm shows the possibilities of ion chromatography systems that are optimized for multiple applications.

Metrohm: Ion chromatography for multiple applications

Ion chromatography for multiple applications

Possibilities of ion chromatography systems that are optimized for multiple applications.

Learn in this webinar how automatic calibration in ion chromatography can help you save time and gain reliability.

Metrohm: Automatic calibration in ion chromatography

Automatic calibration in ion chromatography

Learn in this webinar how automatic calibration in ion chromatography can help you save time and gain reliability.

Learn how you can determine glyphosate and its primary metabolite AMPA in drinking water by ion chromatography in a straightforward manner.

Metrohm: Glyphosate and AMPA analysis by ion chromatography

Glyphosate and AMPA analysis by ion chromatography

Learn how you can determine glyphosate and its primary metabolite AMPA in drinking water by ion chromatography in a straightforward manner.

The future begins with innovation. For 45 years, innovative Thermo Scientific Dionex Ion Chromatography (IC) systems have enabled extraordinary breakthroughs and discoveries. Laboratory professionals like you have been propelling science forward with reliable, reproducible analyses based on Dionex solutions. Confidence drives your passion for excellence and exploration every day.
Your scientific talent, combined with our exceptional IC innovations, continues to deliver impact for the world’s scientific community, empowering health and safety in society and spearheading positive environmental developments.
Together, let us advance IC science for greater future impact. Because we can’t meet in person, we’re meeting virtually – with events happening over three days to conveniently engage all global regions and time zones. One day for Asia, one for Europe and one for the Americas (although you’re welcome to join the symposium any day to post questions and view sessions of interest).
<h3>Attend the virtual event to:</h3>
<ul>
<li>Hear from industry experts about the impact of ion chromatography on applied sciences</li>
<li>Learn how IC is helping your colleagues achieve new advancements</li>
<li>Raise topics pertaining to ion chromatography and its application, which will be addressed by a panel of IC experts in the forum</li>
<li>Browse resources to see how IC can be applied in your lab</li>
</ul>
<h3>27th October (Tuesday) Agenda - Ideal for the Americas</h3>
<ul>
<li>8:00 am PT (17:00 CEST): Plenary Talk: 45 Years of Ion Chromatography – Milestones of the Development (Dr. Joachim Weiss | Technical Director | Thermo Fisher Scientific)
</li>
<li>8:45 am PT (17:45 CEST): What I See Undersea with IC (Nathan F. Dalleska, Ph.D. | Director , Environmental Analysis Center | Caltech)
</li>
<li>9:05 am PT (18:05 CEST): Improved understanding of the hydrogeochemistry of arsenic and selenium in ambient and industrial waters (Dirk Wallschläger | Professor, Environmental Chemistry |Trent University)
</li>
<li>9:25 am PT (18:25 CEST): Fundamentals of IC and Virtual Column (Dr. Charles Lucy | Professor Emeritus | University of Alberta)
</li>
<li>Q&amp;A Session
</li>
<li>9:45 am PT (18:45 CEST): Forum (Facilitator: Dana Stradtner)
</li>
<li>Panelists: Dr. Jeffrey Rohrer (Thermo Fisher Scientific
</li>
<li>Panelists: Kirk Chassinol (Thermo Fisher Scientific)
</li>
<li>Panelists: Michael Hvizd (Thermo Fisher Scientific)
</li>
<li>10:30 am PT (19:30 CEST): End of Day 3
</li>
</ul>

Thermo Fisher Scientific: Global IC Virtual Symposium - Day 3

Global IC Virtual Symposium - Day 3

Reaching further in your metabolomics study with IC, GC and LC-MS analysis.
The comprehensive analysis of small endogenous and exogenous molecules in a biological system results in a better understanding of metabolomic processes. The characterization of metabolic phenotypes enables biomarker discovery, disease taxonomy, and tracking treatment effects. 
The metabolomic challenge includes a large number of compounds with diverse physicochemical properties. This leads to new analytical challenges when a more comprehensive coverage of the metabolic landscape is needed.
High-resolution accurate mass measurement (HRAM) mass spectrometry (MS) is an essential tool in metabolome analysis. Thermo Scientific Orbitrap-based mass spectrometers provide a leading combination of sensitivity, mass accuracy, and resolving power that helps answer the most challenging analytical tasks.
MS, however, suffers from disadvantages such as ion suppression and the differentiation of isomers. The combination of MS with separation techniques addresses such issues. Different chromatographic approaches can be used and fine-tuned to a specific set of metabolites, including polar and ionic compounds, glycans, volatile compounds, and steroids. The comprehensive analysis of the metabolome, however, requires a combination of this method.
<h3>We will present three topics:</h3>
<ul>
<li>The untargeted screening workflow for identification and comparison of different wine origin using the GC Orbitrap technology and Compound discoverer,</li>
<li>The combination of Ion Chromatography (IC) with HRAM to determine polar and ionic components, </li>
<li>A HPLC-Orbitrap example study to showing the changes observed in mice plasma composition depending on the diet type.</li>
</ul>
All experimental data were processed with the Thermo Scientific Compound Discoverer software, to comprehensively profile the samples, detect more compounds, and identify unknowns. 
We will introduce our newest member of the LC-MS family, the Thermo Scientific Orbitrap Exploris mass spectrometer.
<h3>What you will learn:</h3>
<ul>
<li>MS instrumentation designed for exceptional usability resulting in increased productivity in metabolomics</li>
<li>Benefits of high-resolution accurate mass spectrometry (HRAM) in unknown analysis and research</li>
<li>Analytical solutions for sample profiling</li>
<li>Examples of complete IC-MS, GC-MS, and LC-MS workflows for unknown identification using Orbitrap technology and Compound Discoverer software</li>
</ul>
<blockquote>
Presenter: Anas Kamleh (Expert Sales Support, Metabolomics, Thermo Fisher Scientific)
</blockquote>
<blockquote>
Anas joined Thermo Fisher Scientific in 2015 as an application specialist in metabolomics. He is driving a new role since 2018 that entitles supervising collaboration projects and ensuring our hardware and software products provide the best experience for Orbitrap metabolomics users. His industrial and academic background extend to close to 15 years of experience in the field of metabolomics spanning a PhD thesis from University of Strathclyde, Scotland and postdoctoral research positions at Imperial College London and Karolinska Institutet in Stockholm, Sweden.
</blockquote>
<blockquote>
Presenter: Racha Mailler (Sales Support Specialist GCMS/MS, EFS-Industrial, Thermo Fisher Scientific)
</blockquote>
<blockquote>
Racha joined Thermo Fisher Scientific in 2016 as Technical support specialist for GC and GC/MS. She is driving a new role since 2018 as an application specialist for GC, GCMS and Orbitrap technologies. Her role has expand to cover EMEA zone. Her everyday job is to help our GCMS users getting the best out of their instrument by training them on the software and advising them with the method development. Racha holds a PhD degree in Analytical chemistry from the university of Lille 1.
</blockquote>
<blockquote>
Presenter: Detlef Jensen (Sr. Expert, SST, EFS-Industrial, Thermo Fisher Scientific)
</blockquote>
<blockquote>
Detlef holds a Ph.D. in Chemistry from the Technical University Berlin/Germany. For more than 30 years, he covered many positions at Dionex, now Thermo Fisher Scientific in ion chromatography. Since March 2013, he has been supporting our users and field teams all over Europe in his role as European Ion Chromatography Expert.
</blockquote>

Thermo Scientific: Omics Winter Webinars - Metabolomics session 4: Chromatographic solutions

Metabolomics session 4: Chromatographic solutions

Haloacetic acids (HAAs) are disinfection byproducts caused by the reaction of chlorine and naturally occurring dissolved organic matter present in drinking water. Five commonly found HAAs are regulated by the EPA with a Maximum Contaminant Level (MCL) of 60 ug/L.
<blockquote>
Presenter: Emily Parry, PhD (LC/MS Applications Scientist, Agilent Technologies, Inc.)
</blockquote>
<blockquote>
Emily Parry received her PhD degree in Environmental Chemistry from the University of California, Davis. She joined Agilent after completing her postdoctoral work at the Environmental Protection Agency (EPA). Her specialty is method development and measurement of emerging contaminants.
</blockquote>

Agilent Technologies: Haloacetic Acids Analysis by IC-TQ

Haloacetic Acids Analysis by IC-TQ

Over the last few years, attention to food quality and ingredients has seen a massive increase. Public authorities have responded to this demand with more stringent quality standards and labelling requirements (for example, EU regulation 1169/2011 and the US regulation 21CFR101). Hence, fast, robust and reliable analytical techniques have become ever more necessary.
This New Food webinar in association with Metrohm will begin with an overview of the latest analytical techniques used for beverage analyses and the challenges they present. The presenters will then take a closer look at the benefits of ion chromatography for beverage analysis.
The main part of the webinar will guide attendees through the numerous dedicated Metrohm IC applications for beverage analysis. The audience will learn about the versatility of ion chromatography for food testing and how it can help increase the efficiency of their daily routine analytics.
<h3>Key learning objectives:</h3>
<ul>
<li>Understand the advantages of using ion chromatography over competing methods for beverage analysis</li>
<li>Learn how automated inline sample preparation techniques can address the challenge of difficult samples, so they can be analysed completely unattended</li>
<li>Establish how ion chromatography works for multi-parameter analysis of beverages</li>
<li>Learn about the many possible applications of ion chromatography within beverage analysis.</li>
</ul>
<blockquote>
Presenter: Dr Gabriele Zierfels (Senior Product Specialist, Metrohm International)
</blockquote>
<blockquote>
Dr Gabriele Zierfels studied food chemistry and for her PhD developed HPLC methods for the determination of antibiotics in animal food matrices. She worked for almost 14 years as a laboratory manager in the field of textile and leather testing at a leading contract laboratory. During this time, she gained extensive practical expertise in sample preparation techniques and the operation of a diversity of analytical methods, e. g., HPLC, GC-MS, and LC-MS.
</blockquote>
<blockquote>
For more than 10 years, Gabriele has been working at the Competence Center Ion Chromatography at Metrohm International HQ in Switzerland. As a Senior Product Specialist, she is responsible for product and method development, especially for the food industry, as well as for customer support and training.
</blockquote>

Pixabay/bridgesward: Improving your analytics for beverage analysis with ion chromatography

Improving your analytics for beverage analysis with ion chromatography

Sample preparation embraces all operations that help bring samples into a form appropriate for analysis. This includes homogenization of the sample, its dissolution, preservation, and filtration. Sample preparation is a very critical step in the entire analytical procedure because each manipulation of the sample can introduce errors in the analytical workflow. Thus, the care taken in sample preparation directly affects the quality and accuracy of the analytical results. In addition, sample preparation is often difficult to automate and, therefore, the limiting factor regarding sample throughput.
Weakly contaminated aqueous samples with moderate total ionic strength, such as drinking water, can usually be injected directly into an ion chromatograph after filtration. If the sample cannot be analyzed within a short time, sterile filtration of the sample at the point of sampling is required to remove bacteria, which otherwise would alter the sample composition as ions such as nitrite, nitrate, orthophosphate, short-chain fatty acids, and ammonium cannot be preserved in any other way. However, there are numerous application examples requiring the removal of interfering matrix components from the sample, which can be done off-line or as an intermediate first step of the subsequent IC analysis (automated in-line sample preparation). Sample preparation in ion chromatography aims to avoid overloading effects by appropriately diluting the sample, removing interfering matrix components, and/or making ions that are present in very low concentrations accessible to analysis via preconcentration. Thus, sample preparation steps are multifaceted and, depending on the required sample preparation steps, associated with a widely different instrumental setup and time expenditure.
This presentation will review sample filtration and preservation, automated sample dilution, sample preconcentration and calibration based on RFIC-ESP, the type of sample pretreatment cartridges for off-line or in-line matrix elimination, and sample neutralization.
<blockquote>
Presenter: Joachim Weiss (Technical Director, Thermo Fisher Scientific)
</blockquote>
<blockquote>
Dr. Joachim Weiss started his professional career in 1982 as an applications chemist at Dionex Corporation in Germany. He currently holds the position of International Technical Director for the chromatography commercial organization at Thermo Fisher Scientific. He is renowned for his exceptional knowledge in separation science and is a recognized authority on Thermo Scientific™ IC and HPLC instrumentation and applications.
</blockquote>

Thermo Scientific: 2021 IC Solutions Webinar Series

Sample Preparation in Ion Chromatography

There are many challenges in carbohydrate analysis, whether we want a simple profile or to discover the complexity of glycans. To separate all the groups of glycans into their size and charge can be very complicated and challenging, especially with one method.
For many years Thermo Scientific Dionex CarboPac PA100 and PA200 Columns have provided an abundance of information in glycan identification analysis with High-Performance Anion Exchange-Pulsed Amperometry Detection (HPAE-PAD) standalone and with Mass Spectrometry. Here we will find out about the Thermo Scientific Dionex CarboPac PA300 column and what areas we can resolve to understand glycans better, whether it&#39;s O-linked or N-linked, and if it&#39;s charged or neutral.
<h3>Learning points</h3>
<ul>
<li>Latest advances in carbohydrate column technology</li>
<li>Capabilities of the Dionex CarboPac PA300 column</li>
<li>Increase efficiency and cost savings</li>
</ul>
<h3>Who should attend?</h3>
<ul>
<li>Laboratory analysts or researchers performing glycan analysis</li>
<li>Laboratory managers looking to progress and simplify their glycan analysis</li>
<li>Biopharma analysts looking at complex carbohydrates</li>
</ul>
<blockquote>
Presenter: Wai-Chi Man (Product Marketing Manager, Thermo Fisher Scientific)
</blockquote>
<blockquote>
Wai-Chi has over 34 years in Analytical Chemistry experience in a wide range of techniques (IC, LC, GC, CE, MS, NMR, ICP, FTIR, etc), and has specialized in Ion Chromatography for over 32years. She spent 7 years at Wellcome Research supporting Structural Elucidation for Medicinal Chemists with a total of 20 years in the Pharma industry as part of GlaxoSmith Kline, from research, to transferring methods, to manufacturing. She has worked on and has been responsible for many drugs, from diabetes to anti-virals.
</blockquote>
<blockquote>
Moderator: Gemma Ellison (EMEA ICSP Regional Marketing Manager, Thermo Fisher Scientific)
</blockquote>
<blockquote>
Gemma Ellison is the EMEA marketing manager for ion chromatography, sample preparation and discrete analyzer products. As a former analytical chemist, Gemma’s career began in the pharmaceutical industry building expertise in chromatographic and analytical techniques before joining Thermo Fisher Scientific as an ion chromatography and sample preparation specialist for the UK and Ireland. As a specialist Gemma supported a wide variety of application areas and challenges faced by customers giving her a solid understanding of the solutions required. Gemma holds a Bachelor of Science degree in Applied Chemistry from Sheffield Hallam University.
</blockquote>

Thermo Fisher Scientific: Advancing carbohydrate analysis

Advancing carbohydrate analysis - Glycans

Carbohydrate analysis is challenging. Usually, sialic acids, simple mono, and disaccharides to the more complex oligosaccharides require multiple method conditions to separate. The eluents can range from simple hydroxide based eluents to a combination of hydroxide and acetate buffers.
Sourcing the purest chemicals to use for the eluent can be challenging when the production process changes. When manually preparing the eluent, we have to take many cautious steps to ensure good reproducible data, which adds another level of complexity to method preparation. 
Automated eluent generation can simplify carbohydrate analysis by providing cleaner and purer eluents, which in turn resolves challenges in reproducibility, and minimizes maintenance to your instrument. It can save time and resources so we can work smarter and be more productive.
<h3>Learning points:</h3>
<ul>
<li>Capabilities of eluent and dual eluent generation</li>
<li>Latest advances in carbohydrate technology</li>
<li>How to increase productivity and cost savings.</li>
</ul>
<h3>Who should attend:</h3>
<ul>
<li>Laboratory analysts or researchers performing carbohydrate analysis</li>
<li>Analysts analyzing food and beverages for sugar content</li>
<li>Biopharma analysts looking at simple to complex carbohydrates</li>
</ul>
<blockquote>
Presenter: Wai-Chi Man (Product Marketing Manager, Thermo Fisher Scientific)
</blockquote>
<blockquote>
Wai-Chi has over 34 years in Analytical Chemistry experience in a wide range of techniques (IC, LC, GC, CE, MS, NMR, ICP, FTIR, etc), and has specialized in Ion Chromatography for over 32years. She spent 7 years at Wellcome Research supporting Structural Elucidation for Medicinal Chemists with a total of 20 years in the Pharma industry as part of GlaxoSmith Kline, from research, to transferring methods, to manufacturing. She has worked on and has been responsible for many drugs, from diabetes to anti-virals.
</blockquote>
<blockquote>
Moderator: Gemma Ellison (EMEA ICSP Regional Marketing Manager, Thermo Fisher Scientific)
</blockquote>
<blockquote>
Gemma Ellison is the EMEA marketing manager for ion chromatography, sample preparation and discrete analyzer products. As a former analytical chemist, Gemma’s career began in the pharmaceutical industry building expertise in chromatographic and analytical techniques before joining Thermo Fisher Scientific as an ion chromatography and sample preparation specialist for the UK and Ireland. As a specialist Gemma supported a wide variety of application areas and challenges faced by customers giving her a solid understanding of the solutions required. Gemma holds a Bachelor of Science degree in Applied Chemistry from Sheffield Hallam University.
</blockquote>

LCMS webinars focusing on IC - page 11