At the January 2025 CFSRE Seized Drugs Symposium, a Thermo Fisher Scientific–sponsored workshop showcased the potential of <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/2240">Thermo Scientific VeriSpray PaperSpray mass spectrometry </a>(PS-MS) to transform drug analysis workflows in both forensic and clinical toxicology. Three researchers from King’s College London (KCL)—PhD candidate Stefania Boccuzzi and MSc graduates Marwa AlJanahi and Saeed Almheiri—presented their findings on how to optimise this cutting-edge technique for faster, more sensitive, and more cost-effective detection of drugs of abuse.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Advancing_Drug_Analysis_with_Veri_Spray_Paper_Spray_Mass_Spectrometry_040182cb06.jpg" alt="Thermo Fisher Scientific: Advancing Drug Analysis with VeriSpray PaperSpray Mass Spectrometry: Thermo Fisher Scientific’s Edward Goucher and Alexandra Graham pictured beside KCL’s Stefania Boccuzzi and Vincenzo Abbate" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Advancing_Drug_Analysis_with_Veri_Spray_Paper_Spray_Mass_Spectrometry_040182cb06.jpg 245w," sizes="100vw" width="1024" height="512"><h3>Why VeriSpray? A simpler, faster path to results</h3>Traditional LC-MS workflows can be powerful, but when labs are overwhelmed by backlogs, the time and complexity of sample preparation and chromatography can be limiting. VeriSpray offers a remarkably simplified path to MS analysis, directly ionizing complex matrices using a paper substrate—no LC step required.<h5>Key benefits include:</h5><ul><li>&lt;2-minute results thanks to minimal sample prep and elimination of LC</li><li>Reduced cost per test by cutting solvent use and simplifying training requirements</li><li>Automation-ready with support for unattended operation of up to 240 samples</li><li>Seamless integration with Thermo Scientific triple quadrupole systems</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Advancing_Drug_Analysis_with_Veri_Spray_Paper_Spray_Mass_Spectrometry_2_eb1f7dacc2.jpg" alt="Thermo Fisher Scientific: Advancing Drug Analysis with VeriSpray PaperSpray Mass Spectrometry" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Advancing_Drug_Analysis_with_Veri_Spray_Paper_Spray_Mass_Spectrometry_2_eb1f7dacc2.jpg 245w," sizes="100vw" width="700" height="317"><h3>Enhancing emergency toxicology with direct MS analysis</h3>In the emergency room, timely drug identification is critical, but clinicians often rely on patient self-report or symptom-based assessments. Stefania’s PhD research seeks to change that. Her team is developing a rapid, extraction-free method using VeriSpray PS-MS for the targeted analysis of plasma samples from patients presenting with acute drug toxicity.By using dried matrix spots on a paper substrate and coupling this with a <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/404">Thermo Scientific TSQ Altis Plus Triple Quadrupole Mass Spectrometer</a>, Stefania’s work provides an alternative screening technique to chromatography, delivering faster, actionable results to guide early clinical decision-making.<h5>Key takeaways:</h5><ul><li>Paper spray MS is an ambient ionization technique suitable for emergency toxicology due to its rapid results and minimal sample prep.</li><li>Enhancing the paper substrate and adding microextraction steps can boost sensitivity without sacrificing speed.</li></ul><h3>Substrate matters: boosting detection with paper treatment</h3>One key limitation of PS-MS is the interference that can arise from the paper substrate itself. Marwa’s research explored nine different paper treatments, ranging from acids to solvents, to improve the signal-to-blank (S/B) ratio when analyzing eight common drugs in whole blood.The most promising results came from formic acid and nitric acid treatments, which significantly enhanced analyte detection. Although these methods are currently time-consuming, Marwa envisions future industrial-scale production of pre-treated cartridges to support scalable clinical workflows.<h5>Key takeaways:</h5><ul><li>Substrate optimization can significantly reduce background noise in PS-MS analysis.</li><li>Acid-treated paper enhances S/B ratios, enabling more reliable detection of drugs in blood.</li><li>Industrial pre-treatment could make these improvements broadly accessible.</li></ul><h3>DLLME meets paper spray: improving sensitivity in plasma</h3>Saeed Almheiri’s presentation focused on dispersive liquid-liquid microextraction (DLLME) as a sample prep technique to increase sensitivity for PS-MS analysis of drugs in plasma, without adding significant complexity to the workflow.Using DLLME prior to VeriSpray analysis, Saeed demonstrated improved detection limits (as low as 0.3 ng/mL) across a panel of 10 drugs, including buprenorphine, cocaine, and MDMA. Importantly, this method maintained the fast, minimal-prep advantages that make paper spray ionization so appealing. Key takeaways:<ul><li>DLLME enhances analyte extraction from plasma, reducing matrix effects and improving quantitation.</li><li>Combining DLLME with VeriSpray maintains a low-complexity, high-speed workflow.</li></ul><h3>Conclusion: a new frontier for forensic and clinical toxicology</h3>The data shared at this workshop underscores the transformational potential of VeriSpray PaperSpray MS. Whether it’s detecting drugs in plasma for emergency toxicology, enhancing substrate performance, or integrating clever microextraction steps, researchers at KCL are proving that simplified workflows can still deliver high sensitivity and accuracy. As toxicology labs continue to face growing backlogs and limited resources, adopting a faster path to MS analysis with VeriSpray could dramatically change how drugs of abuse are detected and quantified, getting results faster, cutting costs, and ultimately supporting better outcomes in both forensic and clinical environments.<h3>Resources:</h3><ul><li><a target="_blank" rel="noopener noreferrer" href="https://thermofishermarcom.app.box.com/s/gmmhe84v1x9el0fqmh695uszk936iei6">Watch the full workshop on Box- 2025 Seized Drugs Symposium Workshop and the tag is Toxicology</a></li><li>Explore the <a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/labrulez-bucket-strapi-h3hsga3/br_65405_verispray_paperspray_ion_source_br65405_en_756e8e3ec9.pdf">VeriSpray product brochure</a></li><li>Case study – <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/cs_002678_lsms_clinical_verispray_toxicology_cs002678_na_en_a6096123ef.pdf">Paper spray mass spectrometry simplifies and expedites turnaround of drug toxicity screening King’s College London aims to investigate its use in emergency department applications</a></li><li>Case study – <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/cs_000866_ms_verispray_vancouver_island_univ_cs000866_en_0f5ecbd835.pdf">How paper spray mass spectrometry facilitated harm reduction drug checking</a></li><li>Past blogs in this toxicology series<ul><li>Sample prep – <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/article/6189">Sample Preparation Strategies Demystified: Choosing the Right Fit for Your Toxicology Workflow</a></li><li>Tox Explorer – <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/article/6587">Beyond Blood: Sheffield Teaching Hospitals NHS Foundation Trust Develops HRAM-Powered Method for Post-Mortem Toxicology Analysis</a></li></ul></li><li>Stay tuned to register for next years symposium at <a target="_blank" rel="noopener noreferrer" href="http://www.forensicsymposium.org">www.forensicsymposium.org</a></li><li>Check out our <a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/content/lifetech/global/en/home/industrial/forensics/forensic-toxicology/drug-screening-confirmation.html">drug screening and confirmation webpage</a></li></ul>Visit us on&nbsp;<a target="_blank" rel="noopener noreferrer" href="https://www.linkedin.com/showcase/72003132/admin/dashboard/">LinkedIn:</a>&nbsp;#PSMS #VeriSpray #PaperSprayMS #Toxicology<blockquote><h5>Ema Ruzic</h5>Vertical Marketing Manager, Chromatography and Mass Spectrometry Division (CMD)</blockquote>

Advancing Drug Analysis with VeriSpray PaperSpray Mass Spectrometry

<h3><a target="_blank" rel="noopener noreferrer" href="https://www.isc2026.org/">ISC 2026</a></h3>The <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/314">International Symposium on Chromatography (ISC)</a> represents the oldest conference series on separation science. ISC symposia have been organised since 1956 in each even year. ISC is one of the premier meetings series for discussion of all modes of chromatography and separation science with a broad coverage of techniques and applications.The major focus of the symposium will be on the impact of chromatography and separation science to meet the needs of the pharmaceutical, environmental, food and health industry, as well as science and medicine. The symposium programme will reflect these themes and highlight new challenges and emerging opportunities for the science and marketing of separation and detection systems and methods.As an integral part of the scientific programme of lectures and poster sessions, an international exhibition and vendor seminars on instrumentation and services for chromatography, separation science and mass spectrometry will be organised. ISC 2026 will provide the perfect forum for attendees from academia, industry and government research institutions for scientific exchange and networking.<h3>ISC 2026 SYMPOSIUM KEY DATES</h3><h4>6-10 SEPTEMBER 2026</h4><ul><li>15 January 2026: Opening of Early-bird Registration &amp; Abstract submission</li><li>11 March 2026: Deadline for abstract submission (orals)</li><li>21 April 2026: Sending acceptance letters (orals)</li><li>15 May 2026: Deadline of early-bird registration and payment &amp; Author registration deadline (orals)</li><li>1 June 2026: Preliminary detailed program on web</li><li>1 June 2026: Deadline for abstract submission (posters)</li><li>16 June 2026: Sending acceptance letters (posters)<ul><li>Authors who submit their abstracts with a poster preference by 5 May 2026 will be notified of the outcome by 12 May 2026 and will have the opportunity to register at the early-bird rate until 15 May 2026.</li></ul></li><li>30 June 2026: Author registration deadline (posters)</li><li>30 July 2026: Deadline for abstract submission (late-breaking posters)<ul><li>without the possibility of competing for the Best Poster Award</li></ul></li><li>11 August 2026: Sending acceptance letters (late-breaking posters)</li><li>18 August 2026: Author registration deadline (late-breaking posters)</li><li>25 August 2026: Deadline for late registration &amp; payment&nbsp;</li><li>6-10 September 2026: Symposium</li></ul><h3>REGISTRATION</h3><blockquote>👉<a target="_blank" rel="noopener noreferrer" href="https://www.czech-in.org/cmPortalV15/Account/Login?ReturnUrl=%2FcmPortalV15%2FPortal%2FISC26%2Fnormal">Register HERE for the ISC 2026</a></blockquote><h3>ABSTRACT SUBMISSION</h3><blockquote>👉<a target="_blank" rel="noopener noreferrer" href="https://www.czech-in.org/cmPortalV15/Account/Login?ReturnUrl=%2FcmPortalV15%2FPortal%2FISC26%2Fnormal">Submit your Abstract HERE</a></blockquote><h3>SCIENTIFIC PROGRAM</h3><h4>SHORT COURSES</h4><h5>SC 5 Oligonucleotides and Other Biopharmaceuticals</h5>🗓️ SUNDAY, 6 SEPTEMBER 2026🕗 12:30 – 15:45Analysis of nucleic acid and protein-based pharmaceuticalsThe pharmaceutical industry has undergone a profound transformation over the past four decades driven by continuous innovation in therapeutic and prophylactic modalities. While small molecules have been the foundation of medicine for ages, successive waves have introduced biologics such as recombinant proteins and antibodies, in addition to nucleic acid and cell-based products. Each wave has expanded our ability to treat diseases but also challenged us, analytical scientists, to build a toolbox to characterize these ever more complex modalities. This short course will cover chromatographic and mass spectrometric methods for analyzing nucleic acid and protein-based medicines including antisense oligonucleotides (ASOs), small interfering ribonucleic acid (siRNA) and larger nucleic acids such as messenger RNA (mRNA), in addition to monoclonal antibodies (mAbs), antibody-drug conjugates (ADCs) and &nbsp;antibody-oligonucleotide conjugates (AOCs).&nbsp;<h4>Lecturers</h4><h5>Koen Sandra</h5><ul><li>Koen Sandra received a PhD degree in Biochemistry from the Ghent University, Belgium in 2005. After his PhD, he joined Pronota, a molecular diagnostics company where he was active in developing analytical platforms for disease biomarker discovery and in setting up external collaborations. In 2008, he joined RIC, a company that provides analytical support to the chemical, life sciences and pharmaceutical industries, where he holds the position of CEO. As a non-academic scientist, Koen Sandra is author of over 50 highly cited scientific papers and has presented his work at numerous conferences as an invited speaker.</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ISC_2026_Koen_Sandra_2ff9f97b34.jpg" alt="ISC 2026: Koen Sandra" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ISC_2026_Koen_Sandra_2ff9f97b34.jpg 156w," sizes="100vw" width="500" height="500"><h5>Amanda Guiraldelli Mahr</h5><ul><li>Amanda Guiraldelli Mahr is a senior scientist at the RIC group in Belgium, specialized in chromatographic and LC-MS strategies for biopharmaceutical and small molecule analysis. With more than 17 years of experience in analytical development, she leads the design and qualification of procedures for release testing, stability studies, and structural characterization of monoclonal antibodies, peptides, and oligonucleotides, with strong expertise in SEC, IEX, RPLC, HILIC, HIC, and high-resolution MS workflows. She drives the implementation of ICH Q2(R2), Q14, and Analytical Quality by Design (AQbD) principles in collaboration with global biopharmaceutical partners. Amanda serves as a member of the United States Pharmacopeia (USP) Pharmaceutical Analytical Lifecycle and Data Science Expert Committee and is a board member of the ECA Analytical Quality Control Group. Before joining RIC, she spent more than 12 years at USP, where she worked both as a Senior Scientist – leading method development and validation projects, impurity analysis by LC-MS/GC-MS, and reference standards characterization by LC-HRMS – and as a Scientific Affairs Manager, contributing to major standards such as &lt;1220&gt; and &lt;1225&gt; and driving initiatives in AQbD, predictive modeling, and analytical procedure lifecycle management. She holds a bachelor’s degree in Pharmacy–Biochemistry and a Ph.D. in Analytical Chemistry, and has been a visiting scientist at TU Berlin and Leiden University, focusing on LC-HRMS-based protein analysis.</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ISC_2026_Amanda_Guiraldelli_Mahr_0bd046c778.jpg" alt="ISC 2026: Amanda Guiraldelli Mahr" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ISC_2026_Amanda_Guiraldelli_Mahr_0bd046c778.jpg 156w," sizes="100vw" width="500" height="500">

ISC 2026 Short Course 5 - Oligonucleotides and Other Biopharmaceuticals

News from LabRulezLCMS Library - Week 09, 2026

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The International Symposium on Chromatography (ISC) represents the oldest conference series focussing on separation science. ISC symposia have been organised since 1956 in each even year. ISC is internationally recognised as one of the premier meeting series for discussion of all modes of chromatography and separation science with a broad coverage of techniques and applications.

International Symposium on Chromatography - (ISC)

DataApex

Tosoh Bioscience

Agilent Technologies

US HUPO

Phenomenex

SelectScience

SCIEX

<h4>LC-MS/MS fundamentals webinar series 2.0</h4>
Advanced techniques for data acquisition and processing
Elevate your analytical expertise with advanced techniques and workflows
Sharpen your data acquisition and processing skills with our LC-MS/MS 2.0 webinar series. Based on our LC-MS/MS 1.0 webinar series, these sessions will go beyond the fundamentals of LC-MS/MS and introduce ways to advance your analytical methods and data processing workflows.
Every other week, we will explore how to optimize SCIEX OS software with short, 30-minute expert-led presentations.
<h4>This webinar:</h4>
June 18, 2024 11:00 a.m. - 11:30 a.m. CET - It&#39;s a TRAP! Getting the most out of your QTRAP system
Learn when to utilize QTRAP functionality to create more selective and sensitive methods.
<h4>Other webinars from the series:</h4>
May 7, 2024 11:00 a.m. - 11:30 a.m. CET - <a href="https://lcms.cz/webinar/3820">Beyond the fundamentals</a>
May 21, 2024 11:00 a.m. - 11:30 a.m. CET - <a href="https://lcms.labrulez.com/webinar/3852">Advanced MS/MS method building</a>
Gain insight into advanced features for maximizing sensitivity in your mass spectrometry analyses.
June 4, 2024 11:00 a.m. - 11:30 a.m. CET - <a href="https://lcms.labrulez.com/webinar/3853">Mastering chromatography</a>
Discover how to optimize your chromatography for even the most challenging compounds while creating and building LC methods.
July 2, 2024 11:00 a.m. - 11:30 a.m. CET - <a href="https://lcms.labrulez.com/webinar/3855">Troubleshooting at the source</a>
Acquire the knowledge needed to optimize source parameters and identify and resolve ionization-related problems.
July 16, 2024 11:00 a.m. - 11:30 a.m. CET <a href="https://lcms.labrulez.com/webinar/3856">Automating data processing</a>
Learn how to automate your data processing with custom flagging and rules for efficient data review in SCIEX OS software.
July 30, 2024 11:00 a.m. - 11:30 a.m. CET - <a href="https://lcms.labrulez.com/webinar/3857">Excel strategies for mass spectrometry data analysis</a>
Take an in-depth look at when and how to use Excel to increase your productivity.

SCIEX: LC-MS/MS fundamentals webinar series 2.0

It's a TRAP! Getting the most out of your QTRAP system

Sharpen your data acquisition and processing skills with our LC-MS/MS 2.0 webinar series.

Sample-to-sample and run-to-run reproducibility in chromatography is of utmost importance.
What do you do when your chromatography suddenly changes?
In this webinar, we’ll discuss some of the most common chromatography issues that we see as technical support specialists. Whether you have retention time changes, pressure changes, new peaks, ghost peaks, or peak shape changes, troubleshooting these issues can be a challenge. We’ll provide explanations for why these changes may be happening and make recommendations for how to avoid them in the future.
<blockquote>
Presenter: Jean Lane (Application Engineer, Agilent Technologies, Inc.)
</blockquote>
<blockquote>
Jean has been employed with Agilent since Nov 2010 in technical and applications support and has a primary role supporting Agilent’s full line of LC columns and consumables, which also includes support for Agilent’s GPC/SEC product line. She came to Agilent thru acquisition of Varian and the former Polymer Laboratories. Jean has 20 plus years of technical and applications support for both HPLC and GPC consumable products. In addition to practical chromatography experience in the laboratory, she has had many, many years in her technical role involving customer support providing assistance and troubleshooting for customer chromatography issues.
</blockquote>

Agilent Technologies: My Chromatography Has Changed: Steps for Effective Troubleshooting

My Chromatography Has Changed: Steps for Effective Troubleshooting

We’ll discuss some of the most common chromatography issues that we see as technical support specialists.

Steps for Effective HPLC Troubleshooting

Hear from experts in capillary electrophoresis (CE) at SCIEX.
In this series, you will learn the fundamentals of the classical applications of CE.
You will understand how to develop methods for protein characterization, RNA/DNA analysis and small molecule detection.
You will discover how these techniques are being used mainly in the biopharmaceutical industry but also in food testing and academia. 
<h3>Agenda</h3>
<h5>10:00 Welcome and introduction to SCIEX</h5>
<ul>
<li>Steve Lock, PhD (Senior Market Development Manager, Biopharma, SCIEX)</li>
</ul>
<h5>10:15 Learn how CE-SDS works and how to get the best out of your size mapping of proteins</h5>
<ul>
<li>Marcus Heinl (Senior Field Applications Specialist, SCIEX)</li>
</ul>
<h5>10:45 Understand the differences between cIEF and CZE, and how they both enable charge profiling of proteins</h5>
<ul>
<li>Marcin Moczulski (Senior Specialist Field Applications, SCIEX)</li>
</ul>
<h5>11:15 Find out the latest ways to couple CE with MS detection</h5>
<ul>
<li>Whitney Smith (Senior Support Specialist CE, SCIEX)</li>
</ul>
<h5>11:45 Break / Q&amp;A</h5>
<h5>12:00 Discover how CE can be used for N Glycan analysis</h5>
<ul>
<li>Steve Lock, PhD (Senior Market Development Manager, Biopharma, SCIEX)</li>
</ul>
<h5>12:30 Learn how CE is being used for RNA and DNA analysis and is enabling the development of the latest cell and gene therapy drugs and vaccines</h5>
<ul>
<li>Suki Klair (Field Application Specialist, SCIEX)</li>
</ul>
<h5>13:00 Close / Q&amp;A</h5>
<h5>13:15 End of sessions</h5>

SCIEX: Understanding capillary electrophoresis

Understanding capillary electrophoresis

In this series, you will learn the fundamentals of the classical applications of CE.

Per- and poly-fluoroalkyl substances (PFAS) are persistent chemicals commonly found in surface protectants and fire-fighting foams. Research has revealed that exposure to environmentally relevant concentrations of some PFAS can reduce reproductive success and have other adverse effects on animals. In this webinar, Professor Todd Anderson, from the Department of Environmental Toxicology, Texas Tech University, presents new findings from field studies determining PFAS concentrations in plant and animal tissues. His team have been involved in laboratory and field studies where it was necessary to determine PFAS concentrations in plant and animal tissues to (1) better understand the pathways of PFAS trophic transport from soil to higher organisms, and (2) to determine PFAS burdens in exposed organisms and the potential for maternal transfer of PFAS from adults to offspring.
LC-MS analytical methods for PFAS determination in water and soil matrices provide a solid foundation upon which to make slight changes to improve method performance for extracts of plant and animal tissues. In controlled laboratory studies with an avian model, we’ve used these modified methods with varying degrees of success, to measure PFAS in adult livers, eggs, hatchling livers, and brain tissue (adults and hatchings). These PFAS measurements in tissues allowed for determination of avian Toxicity Reference Values based on survival, growth, and reproduction endpoints, as well as maternal transfer from exposed adults to unexposed hatchlings. In field studies on historical fire training areas, we’ve used these modified methods on a limited set of PFAS analytes, to measure PFAS in vegetation, invertebrates, and small mammal livers. These PFAS measurements have allowed us to better understand the trophic transport pathway(s) from soil to higher organisms based on diet (herbivores, insectivores, omnivores) or activity (grooming, nest building).
Who Should Attend:
Lab Managers and researchers involved in PFAS analysis in Food, Clinical, Environmental, and Industrial field. Researchers interested in expanding their PFAS analysis into the toxicological effects associated with PFAS exposure
Key Learning Points:
<ul>
<li>Understand the pathways of PFAS trophic transport from soil to higher organisms</li>
<li>Determine PFAS burdens in exposed organisms.</li>
<li>Estimate the potential for maternal transfer of PFAS from adults to offspring</li>
</ul>
<blockquote>
Presenter: Todd Anderson (Presidential Research Excellence Professor Department of Environmental Toxicology, Texas Tech University)
</blockquote>
<blockquote>
Presenter: Richard Jack (Global Market Development Manager, Food and Environmental - Phenomenex)
</blockquote>

Phenomenex: PFAS Determination in Matrices Beyond Water and Soil

PFAS Determination in Matrices Beyond Water and Soil

New findings from field studies determining PFAS concentrations in plant and animal tissues. 

Next-generation RNA sequencing unlocks the discovery of novel candidate biomarkers for diagnostic and therapeutic applications, but reproducibility is a key challenge in biomarker discovery programs. Integrating multifaceted quality control (QC) steps can improve design decisions and enhance the confidence and reliability of results.
This webinar will demonstrate how a comprehensive QC framework using the Agilent TapeStation system supports a disease-agnostic biomarker discovery program to identify biologically relevant candidate biomarkers of complex disease. It will also highlight how this framework can be adapted for total RNA sequencing of whole blood, plasma, and serum samples.
Key learning objectives
<ul>
<li>Learn how RNA sequencing enables the discovery of novel candidate biomarkers</li>
<li>Discover how a comprehensive QC framework allows the confident identification of biologically relevant candidate biomarkers</li>
<li>Understand how Agilent TapeStation systems enable reliable QC in RNA sequencing workflows</li>
</ul>
Certificate of attendance
All webinar participants can request a certificate of attendance, including a learning outcomes summary, for continuing education purposes.
<blockquote>
Presenter: Cheryl Sesler, MS (Associate Director of Research, Decode Health, Inc., United States)
</blockquote>
<blockquote>
Presenter: Dr. Annika Dorn (Product Manager, Agilent Technologies, Germany)
</blockquote>

Agilent: The Importance of End-to-End Quality Control Processes for RNA Biomarker Discovery

The Importance of End-to-End Quality Control Processes for RNA Biomarker Discovery

QC framework using the Agilent TapeStation system supports a disease-agnostic biomarker discovery program.

End-to-End QC Processes for RNA Biomarker Discovery

They summed up their research in 60 seconds during the Lightning Talk competition at US HUPO and were determined “the winners”. Now you can hear an extended version of their scientific insights at US HUPO’s webinar featuring the winners and honorable mentions from US HUPO 2024.

US HUPO: The Best of US HUPO 2024: Lightning Talks

The Best of US HUPO 2024: Lightning Talks

Scientific insights at US HUPO’s webinar featuring the winners and honorable mentions from US HUPO 2024.

Extracting DNA and RNA from complex microbial communities poses a challenge. Efficient cell lysis and high-quality recovered nucleic acids are crucial for molecular techniques&#39; success. MP Biomedicals provides comprehensive sample preparation solutions, covering sample grinding, cell lysis, and nucleic acid extraction and optimized purification kits for various complex samples in microbiome research, including stool, gut, skin tissues, saliva, and environmental or agricultural samples. Its latest development enables high-throughput, automated purification of sequencing-grade nucleic acids from dedicated microbiome research samples
Dr. Véronique Karsten, product manager of the Molecular Biology product portfolio at MP Biomedicals, will explain how to thoroughly homogenize and lyse microorganisms in samples for microbiome research. She will also discuss new DNA and RNA extraction kits from MP Biomedicals for high yields from diverse samples, including environmental, water, plant, fecal, and tissue specimens.
Key learning objectives
<ul>
<li>Learn how to obtain a thorough homogenization and lysis of any microorganism from samples used in microbiome research</li>
<li>Explore the new DNA and RNA extraction as well as coextractions kits developed by MP Biomedicals to generate high yields and achieve rapid isolation of genomic DNA and total RNA from environmental and water samples, plant specimens, feces, human and animal tissues</li>
<li>Discover MPure-32™ and MPure-96™ Automatic Nucleic Acid Purification Platforms designed for high-throughput applications and combined kits specially developed for DNA and RNA purification from various samples including feces and environmental samples</li>
</ul>
Who should attend?
<ul>
<li>Scientists involved in metagenomic and metatranscriptomic analysis of human and animal samples</li>
<li>Researchers working in the environmental and agricultural research field (with soil, sediment, water, sludge, compost, rhizosphere, wood, and any other plant specimens as well as food samples)</li>
</ul>
Certificate of attendance
All webinar participants can request a certificate of attendance, including a learning outcomes summary, for continuing education purposes.
<blockquote>
Presenter: Dr. Véronique Karsten (Product Manager of the Molecular Biology product portfolio, MP Biomedicals)
</blockquote>
<blockquote>
Moderator: Charlie Carter (Associate Editor, SelectScience)
</blockquote>

MP Biomedicals: Enhance Microbial World Exploration with Standardized Sample Prep

Enhance Microbial World Exploration with Standardized Sample Prep

How to thoroughly homogenize and lyse microorganisms in samples for microbiome research.

Microbial World Exploration with Standardized Sample Prep

Join our free Webinar. A member of our technical support team will show you the basic operation of Clarity Chromatography Software and answer your questions! We will provide space for your questions.
Two sessions:
<ul>
<li>18.06. 2024 starts at 09:00 CEST
</li>
<li>18.06. 2024 starts at 16:00 CEST
</li>
</ul>

DataApex: Clarity Chromatography Software live demo

Clarity Chromatography Software live demo

A member of our technical support team will show you the basic operation of Clarity Chromatography Software and answer your questions!

Christian Rohrer, Director of Sales &amp; Support – EMEA at Tosoh Bioscience GmbH, will present the next edition of Tosoh Tuesday, a webinar series held by Chromatography Experts. On Tuesday, June 18, Subin Damodaran, Product Manager GPC at Tosoh Bioscience, will introduce you to high-temperature GPC for polyolefin analysis.
Polyolefins are one of the most important classes of polymers in the plastics industry. You will learn how a high temperature gel permeation chromatography (GPC) system coupled with a viscometer enables the detailed analysis of their molecular weight distribution and intrinsic viscosity, thus providing a comprehensive understanding of their molecular structure.
After the webinar, ask your questions during the live Q&amp;A session.

Tosoh Bioscience: Tosoh Tuesday - Seamless Polyolefin Analysis: High-Temperature GPC Made Easy

Seamless Polyolefin Analysis: High-Temperature GPC Made Easy

High temperature gel permeation chromatography (GPC) system coupled with a viscometer enables the detailed analysis of polyolefins.

The PFAS global research and testing community are now being asked to fully characterize PFAS in samples. Targeted analysis relies on a limited number of available reference standards, however it is well known that thousands of PFAS compounds and transformation products exist in the environment. To support laboratories, Thermo Fisher Scientific has worked with collaborators to develop a novel workflow to provide a better understanding of the diversity of PFAS contamination in samples, and at the same time provide meaningful targeted quantitative results in a variety of matrices.
In this webinar, our experts will show a simultaneous targeted quantitative and non-targeted analysis method, with quantitative results down to part-per-trillion levels, for a 250 mL water sample prepared by EPA 1633 protocols. Additionally, non-targeted data is presented for food contact materials and diluted AFFF sample matrices to demonstrate the applicability of the method to solid samples.
Attendees will learn:
<ul>
<li>Why high resolution and accurate mass (HRAM) with LC-Orbitrap instrumentation is a key advantage when trying to precisely describe PFAS components in a sample.</li>
<li>How Thermo Scientific™ Compound Discoverer™ software with a built-in pre-configured PFAS workflow makes it easy to filter for PFAS candidates, and then make identifications based upon extensive compound libraries, fragment databases, and other tools providing a multifaceted approach to exploring unknown PFAS.</li>
<li>How the same HRAM platform provides a solution to both quantify known PFAS and explore unknown PFAS with confidence and convenience, greatly expanding our understanding of this global health and safety concern.</li>
</ul>
<blockquote>
Presenter: Cynthia Grim, M.S. (Product Applications Specialist III, Thermo Fisher Scientific)
</blockquote>
<blockquote>
Cynthia Grim, M.S. is a Product Applications Specialist III in the Environmental and Food Safety Vertical Marketing team. Her previous experience includes secondary metabolite structure elucidation, pharmaceutical drug safety, and environmental testing. Now, her work revolves around developing novel sample preparation and instrument methods for PFAS analysis to prepare for new frontiers in environmental testing across matrix types.
</blockquote>
<blockquote>
Presenter: Richard Cochran, PhD (Senior Application Scientist for LSMS, Thermo Fisher Scientific)
</blockquote>
<blockquote>
Richard Cochran is a Senior Application Scientist for LSMS at Thermo Fisher Scientific, with over 15 years of experience in mass spectrometry, with strong expertise in high resolution mass spectrometry and untargeted analysis. Richard received is PhD in Analytical Chemistry from the University of North Dakota. Prior to joining Thermo Fisher Scientific, Richard was a senior principal investigator within the Center for Aerosol Impacts on Chemistry of the Environment (CAICE, a National Science Foundation Center of Innovation) and served as the director of the Environmental and Complex Analysis Laboratory at the University of California San Diego. Throughout his career he has published more than 20 scientific publications in the area of mass spectrometry, altogether having more than 1,000 citations.
</blockquote>
<blockquote>
Presenter: Ed George (Vertical Marketing Manager, Thermo Fisher Scientific)
</blockquote>
<blockquote>
Ed George has a BS in Chemistry from the University of Notre Dame with concentration in Environmental Science. He worked for 15 years in the environmental laboratory industry, holding positions of Lab Technician, Lab Manager, and R&amp;D Manager, responsible for developing novel sample preparation and analytical methods in soil and water on GC/MS/MS and LC/MS/MS platforms. He participated in several collaborative method development projects with the USEPA. In 2014, he joined Thermo Fisher Scientific and is currently a Senior Applications Scientist. He has worked closely with key collaborators on food safety and environmental projects in universities and industry and has recently developed workflow applications for pesticide and veterinary drug residues in food on both LC/MS/MS and high-resolution MS platforms.
</blockquote>

Thermo Fisher Scientific: LC-Orbitrap MS Workflow for Targeted and Non-Targeted Analysis of over 40,000 PFAS Compounds in Environmental and Food Contact Material Samples

LC-Orbitrap MS Workflow for Targeted and Non-Targeted Analysis of over 40,000 PFAS Compounds in Environmental and Food Contact Material Samples

Simultaneous targeted quantitative and non-targeted PFAS analysis, in 250 mL water sample prepared by EPA 1633 protocols.

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