<p><strong>You may have the best HPLC system on the market, but to maximize your investment, you also need the best software to control the system and manage the data. If the software is complex to use, inflexible or lacking in functionality, it can greatly reduce your lab productivity, creating bottlenecks and inefficiencies. Furthermore, this can lead to unreliable results, increased error rates, cost implications and ultimately, a decrease in overall laboratory performance. By selecting the right Chromatography Data System (CDS) designed to meet current laboratory needs, you can eliminate errors and drive productivity with data that is accurate, trustworthy and secure.</strong></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Elevate_Your_HPLC_Performance_with_a_Modern_CDS_cc757246f7.jpg" alt="Thermo Fisher Scientific: Elevate Your HPLC Performance with a Modern CDS." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Elevate_Your_HPLC_Performance_with_a_Modern_CDS_cc757246f7.jpg 245w," sizes="100vw" width="1024" height="512"></p><h3><strong>Be flexible and be in control</strong></h3><p>So, what if you have multiple HPLC’s from different vendors? <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/76"><strong>Thermo Scientific Chromeleon CDS</strong></a> offers full control over the widest range of HPLC and other chromatography instruments, including those from third-party manufacturers. This ensures you can maintain flexibility, while connecting and controlling your HPLC systems effortlessly. With features, such as auto-generated instrument panels that provide fast access to commands and live analysis plots, you can simplify navigation and enhance the overall user experience, making it easier to manage and monitor instruments.</p><h3><strong>Streamline your method development and validation</strong></h3><p>Support for your method development and validation needs is taken care of with <strong>predefined ICH method validation templates and built-in tools for method conversion, alongside integration with specialized software for automated and intelligent HPLC method development</strong>. This integration facilitates faster and more efficient method optimization and robustness testing, while the secure centralized data storage builds the perfect platform for compliance and future data review, providing a complete solution from method development to validation.</p><h3><strong>Robust compliance and secure data management</strong></h3><p><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/sp_70761_cds_ensure_compliance_sp70761_en_fd2abc669a.pdf"><strong>Compliance and security</strong></a> can be a crucial aspect of any HPLC operation, and Chromeleon CDS effectively addresses these needs. Your instrument management starts with fast integrated wizard-driven instrument qualification covering IQ, OQ and PQ with predefined templates and reports to optimize the instrument qualification process. The software employs a privilege-based approach to control access to both the instruments and the system, ensuring that only authorized and qualified personnel can interact with them. Dedicated instrument audit trails track all actions and will provide you with a full history that is searchable ensuring traceability, safeguarding the integrity of your data and operations.</p><h3><strong>Keep your instruments up and running</strong></h3><p>Productivity is only maintained if your HPLCs are operational and available for use. Integrated diagnostic tests offer insight into key information such as lamp operating hours or piston seal wear with warning limits for timely replacements. The <strong>active monitoring of service and qualification status</strong> allows for convenient maintenance scheduling and prevents unnecessary instrument downtime. An overview of diagnostic outcomes can also be produced as part of a routine health check ensuring that your HPLC instruments are always in optimal condition.</p><h3><strong>Get more right-first-time results</strong></h3><p>How can you prevent delays, time-consuming investigations, and ensure your analytical sequence runs correctly the first time? Chromeleon CDS offers you solutions to minimize user interaction, such as ready checks that automatically verify instrument configuration, methods, and sequences for issues, and automated system equilibration, which ensures the first injection is always good, eliminating the need for blank injections at the start of a sequence saving time and solvent. Automated shutdown procedures will manage a completed run, ensuring safe shutdown, system flushing, or maintaining a low flow rate to prevent component damage. Built-in system suitability tests with the ability to make in-run decisions, such as pause, stop or continue will maintain the integrity of your data and allow you to perform actions like re-injections and auto-dilutions for when samples are outside acceptable tolerance limits.<strong> Streamlining and automating the entire process of sequence creation is achieved through </strong><a target="_blank" rel="noopener noreferrer" href="https://documents.thermofisher.com/TFS-Assets/CMD/brochures/SP-70758-CDS-Chromeleon-Streamline-Workflow-SP70758-EN.pdf"><strong>eWorkflow procedures</strong></a>. These pre-defined templates contain all associated methods and reports, so your HPLC sequence can be automatically generated with just a few clicks, reducing errors, minimizing training, and producing reliable results faster.</p><h3><strong>A software designed to optimize HPLC lab efficiency</strong></h3><p>Chromeleon CDS is a no-compromise solution for your HPLC systems, designed to provide you with faster and better results through enhanced control, flexibility, diagnostics, right-first-time results, and compliance. Its user-friendly interface, comprehensive method development and validation tools, secure data management, and advanced diagnostics make it an indispensable tool for your HPLC laboratory. Find out more by downloading the case study: <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/cs_003880_hplc_vanquish_sanofi_optimize_manufacturing_drugs_cs003880_na_en_cf986bf4cc.pdf"><strong>Leveraging a Vanquish UHPLC system and Chromeleon CDS to optimize the manufacturing process</strong></a> or visiting <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/76"><strong>Chromatography Data System (CDS)</strong></a>.</p><p><strong>Visit us on&nbsp;</strong><a target="_blank" rel="noopener noreferrer" href="https://www.linkedin.com/showcase/72003132/admin/dashboard/"><strong><u>LinkedIn:</u></strong></a><strong>&nbsp;#Chromeleon #ChromatographyDataSystem #HPLC #UHPLC</strong></p><section><blockquote><h5><strong>Peter Zipfell</strong></h5><p>For over 25 years, he has worked extensively with analytical hardware and software transitioning from LC-MS method development through HPLC technical support to chromatography data systems. His focus has always been to support our customers by delivering software solutions across multiple industries to enable them to improve their current workflows and increase productivity.</p></blockquote></section>

Elevate Your HPLC Performance with a Modern CDS

<h3><a target="_blank" rel="noopener noreferrer" href="https://www.isc2026.org/"><strong>ISC 2026</strong></a></h3><p>The <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/314"><strong>International Symposium on Chromatography (ISC)</strong></a> represents the oldest conference series on separation science. ISC symposia have been organised since 1956 in each even year. ISC is one of the premier meetings series for discussion of all modes of chromatography and separation science with a broad coverage of techniques and applications.</p><p>The major focus of the symposium will be on the impact of chromatography and separation science to meet the needs of the pharmaceutical, environmental, food and health industry, as well as science and medicine. The symposium programme will reflect these themes and highlight new challenges and emerging opportunities for the science and marketing of separation and detection systems and methods.</p><p>As an integral part of the scientific programme of lectures and poster sessions, an international exhibition and vendor seminars on instrumentation and services for chromatography, separation science and mass spectrometry will be organised. ISC 2026 will provide the perfect forum for attendees from academia, industry and government research institutions for scientific exchange and networking.</p><h3><strong>ISC 2026 SYMPOSIUM KEY DATES</strong></h3><h4><strong>6-10 SEPTEMBER 2026</strong></h4><ul><li><strong>15 January 2026:</strong> Opening of Early-bird Registration &amp; Abstract submission</li><li><strong>11 March 2026: </strong>Deadline for abstract submission (orals)</li><li><strong>21 April 2026: </strong>Sending acceptance letters (orals)</li><li><strong>15 May 2026: </strong>Deadline of early-bird registration and payment &amp; Author registration deadline (orals)</li><li><strong>1 June 2026: </strong>Preliminary detailed program on web</li><li><strong>1 June 2026: </strong>Deadline for abstract submission (posters)</li><li><strong>16 June 2026: </strong>Sending acceptance letters (posters)<ul><li>Authors who submit their abstracts with a poster preference by 5 May 2026 will be notified of the outcome by 12 May 2026 and will have the opportunity to register at the early-bird rate until 15 May 2026.</li></ul></li><li><strong>30 June 2026:</strong> Author registration deadline (posters)</li><li><strong>30 July 2026:</strong> Deadline for abstract submission (late-breaking posters)<ul><li>without the possibility of competing for the Best Poster Award</li></ul></li><li><strong>11 August 2026: </strong>Sending acceptance letters (late-breaking posters)</li><li><strong>18 August 2026:</strong> Author registration deadline (late-breaking posters)</li><li><strong>25 August 2026: </strong>Deadline for late registration &amp; payment&nbsp;</li><li><strong>6-10 September 2026: </strong>Symposium</li></ul><h3><strong>REGISTRATION</strong></h3><blockquote><p><strong>👉</strong><a target="_blank" rel="noopener noreferrer" href="https://www.czech-in.org/cmPortalV15/Account/Login?ReturnUrl=%2FcmPortalV15%2FPortal%2FISC26%2Fnormal"><strong>Register HERE for the ISC 2026</strong></a></p></blockquote><h3><strong>ABSTRACT SUBMISSION</strong></h3><blockquote><p><strong>👉</strong><a target="_blank" rel="noopener noreferrer" href="https://www.czech-in.org/cmPortalV15/Account/Login?ReturnUrl=%2FcmPortalV15%2FPortal%2FISC26%2Fnormal"><strong>Submit your Abstract HERE</strong></a></p></blockquote><h3><strong>SCIENTIFIC PROGRAM</strong></h3><h4><strong>SHORT COURSES</strong></h4><h5><strong>SC 3 Interpretation of Mass Spectra: Basic Introduction for Chromatographers</strong></h5><p><strong>🗓️ SUNDAY, 6 SEPTEMBER 2026</strong></p><p><strong>🕗 8:30 – 11:45</strong></p><p>Mass spectrometry has become an essential tool in modern liquid chromatography, yet many chromatographers receive limited formal training in mass-spectral interpretation. This introductory short course provides a practical guide to understanding and interpreting mass spectra generated by the atmospheric-pressure ionization techniques coupled with LC: electrospray ionization (ESI), atmospheric-pressure chemical ionization (APCI), and atmospheric-pressure photoionization (APPI). The course begins by outlining the information that mass spectrometry adds beyond a chromatogram and clarifying which analytical questions mass spectrometry can – and cannot – answer. Participants receive a concise refresher on mass-spectrometric fundamentals, along with an introduction to key terminology. The principles and practical consequences of ionization methods are then discussed, with emphasis on how ionization physics, LC conditions, and mobile-phase additives shape spectral appearance. Building on this foundation, the course develops practical skills for interpreting LC-ESI spectra: locating the molecular ion, determining charge state, recognizing common adducts, distinguishing in-source artefacts, and using isotope patterns to support elemental-composition hypotheses. Participants then explore how MS/MS fragmentation provides structural clues, with straightforward rules of thumb for neutral losses and class-specific fragmentation behaviors. The course concludes with an integrative exercise that synthesizes chromatographic, full-scan, and MS/MS information to support spectral interpretation. By the end, participants will be equipped with the essential skills needed to interpret LC-MS spectra effectively and to apply mass-spectrometric reasoning in routine chromatographic analysis.&nbsp;</p><h4><strong>Lecturers</strong></h4><h5><strong>Josef Cvačka</strong></h5><ul><li>Josef Cvačka is head of the Mass Spectrometry Group at the Institute of <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/62"><strong>Organic Chemistry and Biochemistry of the Czech Academy of Sciences</strong></a> and an associate professor at the Faculty of Science, Charles University in Prague. His research focuses on the structural analysis of bioactive organic compounds using advanced mass-spectrometric techniques. He develops methods for pinpointing double-bond and methyl-branching positions in lipids and aims to discover new lipid classes in biological samples. His laboratory also designs new ion sources for MS and HPLC/MS. He teaches and supervises students at Charles University and founded the <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/articles?search=Czech+Museum+of+Mass+Spectrometry"><strong>Czech Museum of Mass Spectrometry</strong></a>.</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Josef_Cvacka_5cc8a0d1d4.jpg" alt="ISC 2026: Josef Cvačka" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Josef_Cvacka_5cc8a0d1d4.jpg 156w," sizes="100vw" width="510" height="510"></p>

ISC 2026 Short Course 3 - Interpretation of Mass Spectra: Basic Introduction for Chromatographers

<p><strong>Eurachem and CITAC welcome analysts interested in the evaluation of chemical analysis uncertainty and in how to use this information in results interpretation. The Eurachem Week 2026 will begin with a training course on “Evaluation of the measurement uncertainty from in-house precision and recovery data” scheduled for Sunday, 10 May 2026. A two-days workshop on “Quality in Analytical Measurements: Uncertainty Evaluation and Results Interpretation” open to all interested participants will take place from 11 to 12 May 2026. On 13 May 2026, the Eurachem Working Groups will convene, followed by the Eurachem General Assembly, which will bring together the Executive and national delegates on 14 and 15 May. Both Working Group Meetings and the General Assembly are restricted to their members.</strong></p><p>The results of qualitative and quantitative chemical analyses should have an acceptable uncertainty, which should ideally be reported and considered in results interpretation.</p><p>For many analytical applications, simplified uncertainty evaluations can determine uncertainty values that meet the defined requirements for this parameter. The workshop will focus on the key technical challenges involved in practical evaluations of measurement uncertainty based on precision and recovery data gathered during in-house method validation and quality control. There will be a discussion of how to model the variation of the measurement uncertainty within the analytical range and how to handle divergent recovery values from the analysis of various reference materials. A session on the use of measurement uncertainty in conformity assessment will explore how the risk of false conformity decisions can be managed.</p><blockquote><h5><strong>New Eurachem guidance on using in-house precision and recovery data will be discussed at the workshop.</strong></h5></blockquote><p>Topics will also include the validation and uncertainty evaluation for qualitative analyses with particular attention to current accreditation requirements for these types of analysis. The last session of the workshop will be dedicated to the evaluation of measurement uncertainty arising from sampling and using it to judge the fitness for purpose, and hence validation, of measurement procedures that include sampling. Four sessions of the workshop will include engaging breakout sessions where participants will have the chance to share their views about challenging aspects of the analytical work. Participants are invited to propose posters and oral communications on session topics or any other relevant topic for analytical chemists or stakeholders of the analytical work.</p><h3><strong>Registration</strong></h3><blockquote><p class="cke-user_style-important"><strong>👉</strong><a target="_blank" rel="noopener noreferrer" href="https://conferences.chemistry.pt/register/eurachem2026"><strong>Register here for the workshop</strong></a></p></blockquote><h4><strong>Registration Fees</strong></h4><h5><strong>Early bird (EUR) - Until April 15th</strong></h5><ul><li><strong>Workshop: Regular participant (11 &amp; 12 May 2026): </strong>400 EUR</li><li><strong>Workshop: Student (11 &amp; 12 May 2026): </strong>250 EUR</li><li><strong>Eurachem Working Group<sup>1</sup> (13 May 2026):</strong> 75</li><li><strong>General Assembly<sup>2</sup> (14 &amp; 15 May 2026): </strong>250</li><li><strong>Training On Uncertainty Evaluation<sup>3</sup> (10 May 2026):</strong> 150</li></ul><h5><strong>After April 15th</strong></h5><ul><li><strong>Workshop: Regular participant (11 &amp; 12 May 2026): </strong>450 EUR</li><li><strong>Workshop: Student (11 &amp; 12 May 2026):</strong> 300 EUR</li><li><strong>Eurachem Working Group<sup>1</sup> (13 May 2026): </strong>100</li><li><strong>General Assembly<sup>2</sup> (14 &amp; 15 May 2026):</strong> 300</li><li><strong>Training On Uncertainty Evaluation<sup>3</sup> (10 May 2026): </strong>200</li></ul><blockquote><p>§ - <strong>50 EUR reduction for members of Eurachem</strong>, CITAC, SPQ, RELACRE, ForMEQ and SPMet at the workshop.</p><p>10% reduction for organisations that registered more than one participant.</p><p><sup>1 </sup>- Working group members</p><p><sup>2</sup> - Eurachem members</p><p><sup>3</sup> - 50% reduction for workshop participants</p></blockquote><h3><strong>Workshop</strong></h3><h4><strong>Eurachem/CITAC Workshop on Quality in Analytical Measurements:</strong></h4><h5><strong>Uncertainty Evaluation and Results Interpretation</strong></h5><p>The results of qualitative and quantitative chemical analyses should have an acceptable uncertainty, which should ideally be reported and considered in results interpretation. For many analytical applications, simplified uncertainty evaluations can determine uncertainty values meeting defined requirements for this parameter. The workshop will focus on the key technical challenges involved in practical evaluations of measurement uncertainty based on precision and recovery data gathered during in-house method validation. It will be discussed how to model the variation of the measurement uncertainty within the analytical range and how to handle divergent recovery values from the analysis of various reference materials. A session on the use of measurement uncertainty in conformity assessment will explore how the risk of false conformity decisions can be managed.</p><p>Topics will also include the validation and uncertainty evaluation of qualitative analyses with particular attention to current accreditation requirements for these types of analysis. The last session of the workshop will be dedicated to the evaluation of measurement uncertainty arising from sampling and using it to judge the fitness for purpose, and hence validation, of measurement procedures that include sampling.</p><p>Four sessions of the workshop will include engaging breakout sessions where participants will have the chance to share their views about challenging aspects of the analytical work. Participants are invited to propose posters and oral communications on session topics or any other relevant topic for analytical chemists or stakeholders of the analytical work.</p><h3><strong>Training Course</strong></h3><h4><strong>Evaluation of the measurement uncertainty from in-house precision and recovery data</strong></h4><ul><li>10 May 2026</li></ul><p>A course on the fundamentals of the evaluation of the measurement uncertainty from in-house precision and recovery data will be held on Sunday, 10 May 2026. This training is targeted for analysts with a basic understanding of the measurement uncertainty concept, how uncertainty components propagate, and how the combined uncertainty is expanded. Following the morning presentation of the theory of uncertainty evaluation, the afternoon will be dedicated to applying the theory to real-world cases. Trainees should have basic skills in using Microsoft Excel spreadsheets and bring a laptop with Microsoft Excel to complete the exercises. The interaction between trainers and trainees will be promoted to guarantee learning efficiency.</p><h5><strong>Trainers:</strong></h5><ul><li>Ricardo Bettencourt da Silva, Faculdade de Ciências da Universidade de Lisboa, Portugal (rjsilva@ciencias.ulisboa.pt)</li><li>Stephen L. R. Ellison - UK National Measurement Laboratory (NML) hosted at LGC, United Kingdom</li><li>Vicki Barwick - UK National Measurement Laboratory (NML) hosted at LGC, United Kingdom</li></ul><h4><strong>Agenda</strong></h4><h5><strong>8:00 Registration</strong></h5><h5><strong>9:00 Opening</strong></h5><h5><strong>9:05 Identifying, combining, and expanding uncertainty components: Theory and examples</strong></h5><h5><strong>9:45 Precision uncertainty: Theory and examples</strong></h5><h5><strong>10:30 </strong>Coffee break</h5><h5><strong>10:50 Trueness-related uncertainty: Theory and examples</strong></h5><h5><strong>12:00 Additional questions and discussion</strong></h5><h5><strong>12:30 </strong>Lunch</h5><h5><strong>13:30 Application example 1</strong></h5><h5><strong>15:30 </strong>Coffee break</h5><h5><strong>15:50 Application example 2</strong></h5><h5><strong>17:00 Additional questions and discussion</strong></h5><h5><strong>17:30 Closing</strong></h5><h3><strong>Venue</strong></h3><p>The series of Eurachem events will be held in:</p><ul><li>Meliã Lisboa Aeroporto ****</li><li>Rua C,2 1749-125 Lisboa, Portugal&nbsp;</li></ul>

Eurachem/CITAC Workshop on Quality in Analytical Measurements 2026

Software

Article

Product

Events

A unique company dedicated to serving science helping our customers drive productivity and accelerate results. Through our premier brands – Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific and Unity Lab Services.

Thermo Fisher Scientific

Eurachem is a European network promoting international traceability of chemical measurements and good analytical practice. It provides expert guidance, supports method validation, uncertainty evaluation, proficiency testing, and facilitates discussion on technical and policy issues in analytical quality.

Eurachem

The International Symposium on Chromatography (ISC) represents the oldest conference series focussing on separation science. ISC symposia have been organised since 1956 in each even year. ISC is internationally recognised as one of the premier meeting series for discussion of all modes of chromatography and separation science with a broad coverage of techniques and applications.

International Symposium on Chromatography - (ISC)

Agilent Technologies

Phenomenex

Waters Corporation

<h4><strong>European Free Educational Webinar Series</strong></h4>
<p><strong>Let&#39;s go back to the basics of Chromatography, Mass Spectrometry, Data Analysis and Trouble-shooting: understanding the importance of the basics will enable you to be more effective in your daily laboratory life.</strong></p>
<h4><strong>EPISODE 4</strong></h4>
<p><strong>Basics of Liquid Chromatography</strong></p>
<p><strong>What will you learn?</strong></p>
<ul>
<li>LC System Components: Pumps and Injectors</li>
<li>LC Detectors: Which one is right for your Application?</li>
</ul>
<blockquote>
<p><strong>Prezenter:</strong> Andrea Gheduzzi (Principal LC Market Dev. Manager, EMEA, Waters Corporation)</p>
</blockquote>
<blockquote>
<p>Andrea has spent more than 30 years in the chromatography field. Across his career he had various roles, service engineer, chromatography lab position, and technical application support manager. He has mainly been dealing with pharma accounts, also supporting LC method development activities using DoE/QbD approaches. In his role as Pharma Business Development Manager at Waters he has further expanded his expertise in AQbD and related applications.</p>
</blockquote>
<blockquote>
<p><strong>Prezenter:</strong> Arjan Timmerman (Pharma Market Development Manager EMEA, Waters Corporation)</p>
</blockquote>
<blockquote>
<p>Arjan Timmerman is a market development manager at Waters working in EMEA. Prior to joining Waters in 2014 he worked for 17 years as an Analytical Scientist in the Small Molecule Pharmaceutical industry in various Chemical and Pharmaceutical late-stage development labs.</p>
</blockquote>
<blockquote>
<p>Since 2023 he became QA/QC market development manager for EMEA working in a dedicated team and focuses on Pharmaceutical workflows, AQbD, Impurities, LC Chromatography and Compliance.</p>
</blockquote>
<h4><strong>What&#39;s next?</strong></h4>
<p>Full Webinar Series Episodes List is available <a href="https://event.on24.com/wcc/r/4551012/F69479929A905500D8B21508527807E5/5385652"><strong>here</strong></a></p>
<p>Back to Basics - Sample Preparation: Theory and Overview</p>
<ul>
<li>Tuesday, May 07, 2024, 11:00 AM CEST</li>
</ul>
<p>Back to Basics - Sample Preparation: Tips &amp; Tricks to make it simple</p>
<ul>
<li>Wednesday, June 05, 2024, 11:00 AM CEST</li>
</ul>
<p>Back to Basics - Theory of Liquid Chromatography</p>
<ul>
<li>Wednesday, July 03, 2024, 11:00 AM CEST</li>
</ul>
<p>Back to Basics - Basics of Liquid Chromatography</p>
<ul>
<li>Tuesday, September 10, 2024, 11:00 AM CEST</li>
</ul>
<p>Back to Basics - Analytical Method Development</p>
<ul>
<li>Wednesday, October 02, 2024, 11:00 AM CEST</li>
</ul>
<p>Back to Basics - The importance of Compliance</p>
<ul>
<li>Tuesday, October 22, 2024, 11:00 AM CEST</li>
</ul>
<p>Back to Basics - Introduction to Mass Spectrometry</p>
<ul>
<li>Wednesday, November 13, 2024, 11:00 AM CET</li>
</ul>
<p>Back to Basics - Troubleshooting your LC and MS Systems</p>
<ul>
<li>Tuesday, December 10, 2024, 11:00 AM CET</li>
</ul>
<p><strong>Not sure to be able to attend live sessions?</strong></p>
<p>Register today and watch the webinars on-demand</p>


Waters Corporation: Back to Bacisc Free Educational Webinar Serries

Basics of Liquid Chromatography

Intro to LC system components: pumps, injectors, and detectors.

<p>Event Overview:</p>
<ul>
<li><p><strong>Principle of Chirality</strong></p>
</li>
<li><p><strong>Chiral Stationary Phases (CSP)</strong></p>
</li>
<li><p><strong>Polysaccharide CSPs and their Chiral Retention Mechanisms</strong></p>
</li>
<li><p><strong>Chiral Method Development: Separation Modes and Screening Protocol</strong></p>
</li>
<li><p><strong>SFC Chiral Method Development</strong></p>
</li>
<li><p><strong>Chiral Method Optimization: Case Study</strong></p>
</li>
</ul>
<p>Who Should Attend:</p>
<ul>
<li><p>Any LC users who would like to understand how chiral separations work and how to apply the principles of chiral theory in developing an analytical method for separation of enantiomers.</p>
</li>
<li><p>Any analyst who wishes to learn the basics of chiral theory.</p>
</li>
<li><p>Any academic or pharmaceutical scientists who need to develop a method for separation and characterization of chiral compounds.</p>
</li>
</ul>
<p>Key Learning Points:</p>
<ul>
<li><p><strong>Learn what chiral compounds are and how they are separated using LC and what a chiral stationary phase (CSP) is and the different types there are</strong></p>
</li>
<li><p><strong>Understand the three critical components of Polysaccharide CSPs and review the difference between coated and immobilized CSPs and how they are applied in different analytical contexts</strong></p>
</li>
<li><p><strong>Learn how to approach a chiral screen using different separation modes.</strong></p>
</li>
</ul>
<blockquote>
<p><strong>Presenter:</strong> Laura K Ward (Technical Specialist, Phenomenex)</p>
</blockquote>
<blockquote>
<p>Laura Ward is a Technical Specialist for the Asia-Pacific region with Phenomenex, located in New Zealand. She completed an Honours thesis in the field of Geochemistry at the University of Sydney, Australia where she discovered a love for Analytical Chemistry. Following her academic pursuits, Laura joined Phenomenex Australia as a Technical Sales Consultant where she supported various industries and laboratories. After 5 years and a move to New Zealand, she has joined the Phenomenex Technical Team where she supports scientists globally with their method development, troubleshooting and application support.  In her spare time Laura enjoys being outdoors in the New Zealand countryside and cooking from scratch, most recently venturing into cheesemaking!</p>
</blockquote>


Phenomenex: LC Chiral Theory and Method Development

LC Chiral Theory and Method Development

Learn what chiral compounds are and how they are separated using LC and what a chiral stationary phase (CSP) is and the different types there are.

<div class="summary-section section"><p id="isPasted"><span class="summary" name="summary"><strong>This webinar will introduce liquid chromatography and provide a comprehensive overview of an HPLC system, helping new users understand the purpose of each component. It will also explore some common chromatographic terms, what they mean to the separation, and how understanding these terms can help analysts make better decisions. Finally, we will discuss the attributes of chromatographic columns and how they impact the separation process.</strong></span></p><h5><span class="summary" name="summary">Key Learnings:</span></h5><p><span class="summary" name="summary">1. HPLC system overview</span></p><p><span class="summary" name="summary">2. Key chromatographic terms</span></p><p><span class="summary" name="summary">3. Chromatography overview</span></p><p><span class="summary" name="summary">4. Understanding the chromatographic column</span></p><p>&nbsp;</p><div style="clear:both;"><span class="summary" name="summary">Who should attend: Analysts who are brand new to HPLC or those who need a strong understanding of the principal concepts of HPLC.</span></div><div style="clear:both;">&nbsp;</div><blockquote><div><span class="sp-name"><strong>Presenter: </strong>Maureen DeLoffi (</span><span class="sp-title">Senior Product Manager, </span><span class="sp-company">Waters Corporation)</span></div><div><br><span class="sp-description">Maureen DeLoffi is a Senior Product Manager at Waters Corporation, where she manages the small molecule portfolio of Analytical HPLC columns. Prior to her Product Manager role, she spent over 12 years as a scientist in the Column Technology Development Lab at Waters. She holds a bachelor’s degree in Mechanical Engineering from the University of New Hampshire.</span></div></blockquote></div>

Waters Corporation: Fundamentals of HPLC Separations for Small Molecule Analyses

Fundamentals of HPLC Separations for Small Molecule Analyses

This webinar will introduce liquid chromatography and provide a comprehensive overview of an HPLC system.

<p><strong>We start the LC Beginner webinar series with an overview of basic terms relevant to liquid chromatography.&nbsp;</strong></p><blockquote><p><strong>Presenter:</strong> Laura Montis (Product Specialist Liquid Phase Separations, Agilent)</p><p>Laura began her carrier in the Liquid Chromatography over 15 years ago. After experiencing the pharmaceutical world in an analytical development lab, she went on to work with preparative chromatography and gained experience with Supercritical Fluid Chromatography prior to moving onto special HPLC applications, like 2DLC and Online LC.</p><p>Throughout her career, Laura has held several positions, including application chemist, trainer, sales specialist, and marketing business development. She is currently Product Specialist for liquid phase chromatography systems within the International Distributor Organization in EMEA at Agilent Technologies.</p><p>Laura studied analytical chemistry and holds a master’s degree from University of Lyon in France.</p></blockquote>

Agilent Technologies: HPLC Beginner Webinar Series

Liquid Chromatography Fundamentals

We start the LC Beginner webinar series with an overview of basic terms relevant to liquid chromatography. 

<div class="summary-section section"><section class="section-padding"><div class="page-width"><div class="page-padding"><ul><li><strong>Reversed phase or normal phase?</strong></li><li><strong>Fully porous, partially porous, end capping?</strong></li></ul><p><strong>In this webinar we will cover different stationary phases (RP and NP) and the selection of the particle</strong>.</p><blockquote><p><strong>Presenter:</strong> Ceci<span class="sp-name">lia Mazza (</span><span class="sp-title">Product Specialist, EMEA IDO - Chemistries &amp; Suppliers, </span><span class="sp-company">Agilent)</span></p><p><span class="sp-description">With more than 20 years of professional experience, Cecilia is presently the Product Specialist for columns and supplies at Agilent. Supporting distributors and laboratory users in the analysis and purification of small and large molecules, for a wide range of LC and GC applications as well as sample preparation.</span></p><p><span class="sp-description">Cecilia holds a Ph.D. in Chemical Engineering from Rensselaer Polytechnic Institute in US.</span></p></blockquote></div></div></section></div>

Stationary Phases in HPLC - Part I

In this webinar we will cover different stationary phases (RP and NP) and the selection of the particle.

<p><strong>In the second part of the stationary phases webinars, we look at other separation modes: IEX, SEC, ligand exchange and HILIC and what we think they are best suited for.</strong></p><blockquote><p><strong>Presenter:</strong> Ceci<span class="sp-name">lia Mazza (</span><span class="sp-title">Product Specialist, EMEA IDO - Chemistries &amp; Suppliers, </span><span class="sp-company">Agilent)</span></p><p><span class="sp-description">With more than 20 years of professional experience, Cecilia is presently the Product Specialist for columns and supplies at Agilent. Supporting distributors and laboratory users in the analysis and purification of small and large molecules, for a wide range of LC and GC applications as well as sample preparation.</span></p><p><span class="sp-description">Cecilia holds a Ph.D. in Chemical Engineering from Rensselaer Polytechnic Institute in US.</span></p></blockquote>

Stationary Phases in HPLC - Part II

We look at other separation modes: IEX, SEC, ligand exchange and HILIC and what we think they are best suited for.

<h4><strong>The Waters 2024 Virtual Summer School - An Educational Journey to Master Food &amp; Environmental Analysis</strong></h4><p>Unlock the full potential of LC-MS techniques with our immersive and educational sessions at the Waters Virtual F&amp;E Late Summer School 2024. From September 24th to 26th, engage with leading experts and discover cutting-edge methods for environmental and food analysis.</p><h5><strong>Why attend?</strong></h5><ul><li><strong>Comprehensive Learning:</strong> Dive deep into advanced LC-MS techniques and gain practical knowledge to enhance your laboratory's analytical capabilities.</li><li><strong>Expert Insights:</strong> Learn from industry leaders and gain firsthand experience through detailed modules on chromatography, mass spectrometry, and sample preparation.</li><li><strong>Regulatory Compliance:</strong> Stay ahead with the latest insights on EU regulations for PFAS analysis in food and water, ensuring your lab meets stringent standards.</li></ul><h3><strong>Episode #1: Chromatography - UPLC | F&amp;E Summer School - Day 1 - Module 1</strong></h3><p>This section will provide an overview of the Waters reference material available to customer to help plan the best columns and chromatographic conditions for their LC-MS methods, using common environmental contaminants as an example. We highlight how to create LC-MS methods using the Acquisition Method Editor (AME) application within waters_connect™. Finally, this section will cover some of the most troubleshooting issues: contaminated blank peaks, poor peak shape, etc, and how to address them.</p><h5><strong>What you'll learn:</strong></h5><ul><li>Important factors for developing a UPLC method - considering analyte solubility, pKa and partitioning coefficient (Kow)</li><li>Selecting the most appropriate UPLC column for your analytes</li><li>Setting up LC-MS methods in the waters_connectTM console</li><li>Troubleshooting common contamination issues</li></ul><blockquote><p><strong>Presenter: </strong>Nicole Baumgarten (Sr Sales Applications Chemist, Waters Corporation)</p><p>Nicole is part of the Customer Success team at Waters with a focus on LC-MS/MS application and sales support. She works in this role for more than 9 years and gained experience in previous roles as analyst for biopharmaceuticals in process controls at Boehringer Ingelheim and research Assistent at Zentrum für Humangenetik und Laboratoriumsmedizin in Munich after finishing a Master of Chemical engineering at Hochschule Fresenius, Idstein.</p><p><strong>Presenter: </strong>Caroline Davis (Sr Sales Applications Chemist, Waters Corporation)</p></blockquote>

Waters Corporation: The Waters 2024 Virtual Summer School

Chromatography - UPLC

An overview of the Waters reference material available to customer to help plan the best columns and chromatographic conditions for their LC-MS methods.

Chromatography - UPLC 

<h4><strong>The Waters 2024 Virtual Summer School - An Educational Journey to Master Food &amp; Environmental Analysis</strong></h4><p>Unlock the full potential of LC-MS techniques with our immersive and educational sessions at the Waters Virtual F&amp;E Late Summer School 2024. From September 24th to 26th, engage with leading experts and discover cutting-edge methods for environmental and food analysis.</p><h5><strong>Why attend?</strong></h5><ul><li><strong>Comprehensive Learning:</strong> Dive deep into advanced LC-MS techniques and gain practical knowledge to enhance your laboratory's analytical capabilities.</li><li><strong>Expert Insights:</strong> Learn from industry leaders and gain firsthand experience through detailed modules on chromatography, mass spectrometry, and sample preparation.</li><li><strong>Regulatory Compliance:</strong> Stay ahead with the latest insights on EU regulations for PFAS analysis in food and water, ensuring your lab meets stringent standards.</li></ul><h3><strong>Episode #2: Tandem Quadrupole MS and MS-Method Development | F&amp;E Summer School - Day 1 - Module 2</strong></h3><p>In this episode it’s all about the tandem quadrupole mass specs and the setup of MS-methods. We will demonstrate, using actual hardware, how simple it is to prevent contamination or clean a system, regardless of whether it’s at the low or high end of the sensitivity spectrum. You will learn valuable tips and tricks about UniSpray, a unique ion source and alternative to ESI.</p><p>With our new waters_connect for Quantitation software, we will guide you through the different stages of MS-method development. You will learn how straightforward automated compound optimization can be, and how intuitively the new Method Acquisition Editor can be utilized by operators providing a clear structured all in one view of compounds and parameters. Search options make it easy to navigate through large multi-residue methods. And in the end, you are just one click away from the processing method that will be the topic of Episode 4.</p><h5><strong>What you'll learn:</strong></h5><ul><li>Easy operation and maintenance of Waters TQ-MS systems</li><li>Usage and benefits of UniSpray ion source</li><li>Step by step MS-method development with waters_connect for Quantitation</li></ul><blockquote><p><strong>Presenter:&nbsp;</strong>Benjamin Wuyts, PhD (Senior Solution Support Specialist Europe, Waters Corporation)</p><p>Benjamin initially joined Waters as an application chemist working in the Belgian demo lab, performing liquid chromatography-mass spectrometry demonstrations, support and training. In 2016 Benjamin became a European application chemist focusing on projects to support emerging applications. Benjamin has been focused over several years in establishing the Waters solution to the analysis of polar anionic pesticides, utilising novel column phases and LC-MS/MS technologies.</p></blockquote>

Tandem Quadrupole MS and MS-Method Development

In this episode it’s all about the tandem quadrupole mass specs and the setup of MS-methods.

<h4><strong>The Waters 2024 Virtual Summer School - An Educational Journey to Master Food &amp; Environmental Analysis</strong></h4><p>Unlock the full potential of LC-MS techniques with our immersive and educational sessions at the Waters Virtual F&amp;E Late Summer School 2024. From September 24th to 26th, engage with leading experts and discover cutting-edge methods for environmental and food analysis.</p><h5><strong>Why attend?</strong></h5><ul><li><strong>Comprehensive Learning:</strong> Dive deep into advanced LC-MS techniques and gain practical knowledge to enhance your laboratory's analytical capabilities.</li><li><strong>Expert Insights:</strong> Learn from industry leaders and gain firsthand experience through detailed modules on chromatography, mass spectrometry, and sample preparation.</li><li><strong>Regulatory Compliance:</strong> Stay ahead with the latest insights on EU regulations for PFAS analysis in food and water, ensuring your lab meets stringent standards.</li></ul><h3><strong>Episode #3: Introduction Non-target Screening (NTS) | F&amp;E Summer School - Day 1 - Module 3</strong></h3><p>Suspect and non-target screening (NTS) are crucial techniques used in various fields, including food analysis, environmental studies, toxicology, and doping analysis. In this overview, we’ll discuss a holistic approach and introduce high-resolution mass spectrometry methods for both Suspect and NTS screening. Topics covered include resolution, accurate mass data, and ion mobility.</p><p>In an ideal scenario, Suspect screening and non-Target screening are closely interconnected. Prior knowledge about a potential analyte (Suspect) can expedite the non-Target screening process. We’ll briefly explore Suspect screening and how high-resolution mass spectrometry offers identification criteria for confidently identifying suspect compounds.</p><p>Further, we examine the data gathered for non-target compounds through high-resolution mass spectrometry. In this module we give a concise introduction to the valuable data that can be compiled for assigning structures. In the forthcoming module 4b we will delve into how this data, in conjunction with the tools offered by the waters_connect software, can be conveniently accessed by the user and provide more comprehensive insights.</p><h5><strong>What you'll learn:</strong></h5><ul><li>What is Screening? (Target/ Suspect &amp; Non-Target Screening)</li><li>Basics of HRMS (Resolution and accurate mass)</li><li>Identification criteria for Targets /Suspects &amp; UNIFI Scientific Library</li><li>Tools for Non-Target Screening</li><li>Short introduction of exemplary instrument types</li><li>Xevo G3 QToF for Routine Screening</li><li>Xevo MRT for Screening with very high-resolution and very high mass accuracy</li><li>Select Series Cyclic IMS for Screening with ion-mobility utilizing CCS-values</li></ul><blockquote><p><strong>Presenter:&nbsp;</strong>Christoph Thomas (Principal Sales Applications Chemist, Waters Corporation)</p><p>Christoph Thomas is a Principal Sales Applications Chemist from the Central Europe Customer Success Team based in Eschborn, Germany. He has more than 25 years’ experience in the field of Chromatography and Mass Spectrometry and is familiar with several application areas using Quadrupole and Tof instruments. Within the last decade his projects were mainly focused on the waters_connect Screening Solution in food and environmental screening, toxicology screening, metabolite identification and in the field of extractables and leacheables.</p><p><strong>Presenter:&nbsp;</strong>Gunnar Weibchen (Principal MS Sales Dev Specialist, Waters Corporation)</p><p>Gunnar studied Chemistry and obtained a PhD in Organic and Analytical Chemistry in Hamburg. After working as an Application Chemist in the demo laboratory at Varian, has been with Waters in Sales and Marketing since 2010</p></blockquote>

Introduction Non-target Screening (NTS)

We’ll discuss a holistic approach and introduce high-resolution mass spectrometry methods for both Suspect and NTS screening.

<h4><strong>The Waters 2024 Virtual Summer School - An Educational Journey to Master Food &amp; Environmental Analysis</strong></h4><p>Unlock the full potential of LC-MS techniques with our immersive and educational sessions at the Waters Virtual F&amp;E Late Summer School 2024. From September 24th to 26th, engage with leading experts and discover cutting-edge methods for environmental and food analysis.</p><h5><strong>Why attend?</strong></h5><ul><li><strong>Comprehensive Learning:</strong> Dive deep into advanced LC-MS techniques and gain practical knowledge to enhance your laboratory's analytical capabilities.</li><li><strong>Expert Insights:</strong> Learn from industry leaders and gain firsthand experience through detailed modules on chromatography, mass spectrometry, and sample preparation.</li><li><strong>Regulatory Compliance:</strong> Stay ahead with the latest insights on EU regulations for PFAS analysis in food and water, ensuring your lab meets stringent standards.</li></ul><h3><strong>Episode #4: Chromatography - APGC | F&amp;E Summer School - Day 1 - Module 4</strong></h3><p>Discover the advantages of GC coupled to MS under atmospheric pressure (Atmospheric Pressure GC/ APGC) as a powerful alternative to electron ionization (EI) for GC-MS. Gain a comprehensive understanding of the APGC technology and its operational principles. Explore why APGC offers higher sensitivity, selectivity, and robustness compared to traditional EI methods. Maximize versatility and efficiency by understanding how to achieve both LC and GC capabilities on the same MS system as well as using nitrogen as an alternative carrier gas.</p><h5><strong>What you'll learn:</strong></h5><ul><li>How APGC works</li><li>Enhanced performance over classic EI-GC</li><li>Ease of use and implementation in the lab</li><li>Usage of nitrogen as GC carrier gas</li></ul><blockquote><p><strong>Presenter:&nbsp;</strong>Frank L. Dorman, PhD, FRSC (Principal Environmental Market Manager, Waters Corporation)</p><p>Frank Dorman is currently Senior Business Development Manager for Waters focusing on their global environmental business and, concurrently, Associate Professor (adjunct) in the Department of Biochemistry and Molecular Biology (BMB) at Penn State University in University Park, PA. In his role at Waters, Frank manages the research-focused environmental market, external collaborations and also interfaces with R&amp;D for new product development. Prior to Waters, Frank was employed full-time as a tenure-line Faculty member of Penn State and served as a member of the Graduate Faculty in: Biochemistry, Microbiology and Molecular Biology (BMMB), Chemistry (CHEM) and the Programs in Forensics Science (FRNSC), and Biogeochemistry (BGC). Frank is also a member of the Center for Molecular Toxicology and Carcinogenesis at Penn State. Frank’s scientific interests are in gas and liquid chromatography fundamental characterization, instrumentation and column development, as well and mass spectrometry and atomic spectroscopy as applied to trace analysis in complex sample matrices. This work is directed towards environmental forensics, traditional forensic chemistry and where environmental exposure events may contribute to human disease; an area sometimes referred to as “exposomics”.</p><p>Prior to joining the faculty at PSU, Frank was at Restek Corporation for 14 years as the Director of Technical Development, and R&amp;D Senior Chemist. During most of this same time, Frank was also an Adjunct Research Professor at Juniata College where he maintained an active undergraduate research program. Prior to that he was at Inchcape Testing Services for 5 years as a Senior Chemist, Organics Section Manager for Sample Preparation and Corporate Methods Development Chemist. As such, Frank has extensive experience in both the Industrial and Academic sectors giving him a relatively rare combination of skills and experience.</p><p><strong>Presenter:&nbsp;</strong>Janitha De-Alwis (Senior Applications Chemist, European Applications Team, Food and Environmental, Waters Corporation)</p><p>JD has worked in the chromatography industry for over 10 years and has recently joined Waters Corporation as a senior applications chemist. Prior to joining Waters, JD managed a group at a leading food research and contract organisation. Here, JD helped the food, drink and associated industriesproactivelyand reactively in the area of chemical toxins.As a senior applications chemist, JD now develops new applications with Waters technologies and helps customers with their critical analytical challenges.</p></blockquote>

Chromatography - APGC

Discover the advantages of GC coupled to MS under atmospheric pressure (APGC) as a powerful alternative to electron ionization (EI) for GC-MS.

LCMS webinars focusing on Academy/Principles - page 13

Chromatography - APGC

Introduction Non-target Screening (NTS)

Tandem Quadrupole MS and MS-Method Development

Stationary Phases in HPLC - Part II

Chromatography - UPLC

Stationary Phases in HPLC - Part I

LC Chiral Theory and Method Development

Fundamentals of HPLC Separations for Small Molecule Analyses

Liquid Chromatography Fundamentals

Basics of Liquid Chromatography

Related content

ISC 2026 Short Course 3 - Interpretation of Mass Spectra: Basic Introduction for Chromatographers

Elevate Your HPLC Performance with a Modern CDS

Eurachem/CITAC Workshop on Quality in Analytical Measurements 2026