The human body is the most sophisticated atomic engineer. This idea underpins a breakthrough technology developed by an international research team led by scientists from the Czech Advanced Technology and Research Institute (CATRIN) at Palacký University Olomouc and the Centre for Energy and Environmental Technologies (CEET) at VSB – Technical University of Ostrava. By drawing inspiration from the way enzymes function in the human body, the researchers have created a novel material that could fundamentally change the industrial production of hydrogen peroxide and other important chemicals. The new approach simplifies the production process, eliminates the need for toxic organic solvents and expensive precious metals, and requires only sunlight, oxygen and water to operate. The results <a target="_blank" rel="noopener noreferrer" href="https://www.nature.com/articles/s41467-025-67189-3">were published by the prestigious journal Nature Communications</a>, which ranked the study among the 50 most significant scientific discoveries of the year.Hydrogen peroxide is one of the most important industrial chemicals. It is widely used not only in the chemical industry but also in pharmaceuticals, medicine, the textile industry and water-treatment technologies. The global hydrogen peroxide market is estimated to exceed USD 5 billion annually. Conventional production involves a multistep process that relies on toxic organic solvents and costly palladium-based catalysts. In addition, both the starting chemicals and the resulting waste products can have negative impacts on human health and the environment.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CATRIN_Cesti_vedci_vyvinuli_material_pro_vyrobu_chemikalii_z_vody_a_slunce_Inspirovali_se_lidskymi_enzymy_2_c4d5ecbafb.webp" alt="CATRIN: Czech scientists develop a material for producing chemicals from water and sunlight, inspired by human enzymes" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CATRIN_Cesti_vedci_vyvinuli_material_pro_vyrobu_chemikalii_z_vody_a_slunce_Inspirovali_se_lidskymi_enzymy_2_c4d5ecbafb.webp 208w," sizes="100vw" width="1600" height="1200">“Our aim was to develop a material that enables the efficient, environmentally friendly and affordable production of hydrogen peroxide. When designing this photocatalyst, we were inspired by the structure and behaviour of enzymes in the human body. The result is a technology that does not require toxic organic solvents or expensive precious metals and instead uses a low-cost material based on carbon, nitrogen and copper. It operates in water using only sunlight and oxygen from the air,” said Radek Zbořil, leader of research teams at CATRIN and CEET.In developing the new photocatalyst, the Czech scientists mimicked the function of cytochrome c oxidase—an enzyme that enables human cells to obtain energy by transferring electrons to oxygen. This process relies on copper atoms embedded in the enzyme’s structure, and it was precisely this mechanism that the researchers sought to reproduce.“We very precisely replicated the chemical environment of metals within the enzyme’s structure and anchored copper atoms onto the surface of extremely small carbon nanoparticles with photocatalytic properties. When exposed to light, highly efficient electron transfer occurs between the carbon nanoparticles, the copper atoms and oxygen molecules. This process closely resembles an enzymatic reaction and enables high hydrogen peroxide production,” explained the first author of the study, Lukáš Zdražil, who is affiliated with both CATRIN and CEET.Producing hydrogen peroxide using sunlight and water has been a long-standing goal of research teams worldwide, as it eliminates the use of toxic organic solvents and avoids the formation of hazardous by-products. Until now, however, research in this area has largely remained at an academic level, mainly due to the use of noble metals and often complex photocatalyst designs. Laboratory studies have also resulted in relatively low hydrogen peroxide yields, which could not compete with existing industrial processes.“The new photocatalyst achieves hydrogen peroxide production rates up to two orders of magnitude higher than all previously reported systems, bringing us much closer to industrial requirements. In addition, the material is completely non-toxic, easily recyclable and reusable,” added Zdražil.The Czech teams are now focusing on potential applications of this technology in decentralised production units. Such systems could enable efficient, local production of hydrogen peroxide, for example for use in agriculture, pharmaceutical manufacturing or environmental applications. The combination of solar energy and materials inspired by enzymatic systems may also lead to further promising advances.“I believe that mimicking the structures and functions of iron- and copper-based enzymes could pave the way for other innovative technologies in the chemical industry and pharmaceuticals, such as the production of epoxides, alcohols or phenols,” concluded Zbořil.

 Czech scientists develop a material for producing chemicals from water and sunlight, inspired by human enzymes

<h4>"Education is central to how I approach research"</h4>Analytical scientist Dr Bob Pirok of the Van ‘t Hoff Institute for Molecular Sciences has been awarded the 19th annual ‘Emerging Leader in Chromatography Award’ by LCGC International, a well-known global publisher in the field of separation science. Pirok will receive the award at the upcoming Pittcon 2026 conference held 7-11 March in San Antonio, Texas.With the Emerging Leader in Chromatography Award, LGCG International recognises the achievements and aspirations of talented early-career separation scientists who have made strides toward the advancement and applications of chromatography techniques. Pirok is honoured for his work in the development of comprehensive two-dimensional liquid chromatography (LC×LC), automated method development, and chemometric data analysis.Already in his early career, Pirok has emerged as a prominent figure in addressing long-standing challenges in LC×LC, which include method complexity, data interpretation, and experimental optimisation. His research is characterised by close interaction between theory, instrumentation, and application, as well as sustained collaboration with academic and industrial partners. On a mission to transform advanced chromatographic techniques into practical and robust analytical tools, Pirok has authored or co-authored more than 50 peer-reviewed publications and established an internationally visible research program at the interface of separation science, statistics, and artificial intelligence. All this within a few years of receiving his PhD in 2019.<h4>Automated method development</h4>Central to Pirok’s research is the novel modular AutoLC platform, which enables prototype automated method development. With a capacity to run unsupervised (i.e. without human input), it is able to tackle samples of unknown composition by autonomous analysis of (2D-)LC(-MS) data. It is flexible, able to support different optimization strategies and capable of integrating tools developed by scientists in the global chromatographic community.Accessibility and sustainability are key motivations behind AutoLC, says Pirok: “State-of-the-art separation technology is often overly sophisticated. We aim to make it more robust, automated, and usable beyond a small group of specialists, as efficiently as possible. By providing more detailed and reliable molecular information, such technologies can better inform molecular design and accelerate the development of new materials and applications.”<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/HIMS_From_left_to_right_Bob_Pirok_Prof_Peter_Schoenmakers_Ph_D_candidate_Gerben_van_Henten_and_postdoc_researcher_Tijmen_Bos_in_the_Auto_LC_lab_at_the_Van_t_Hoff_Institute_for_Molecular_Sciences_a4fe9bc6f7.jpg" alt="HIMS: From left to right: Bob Pirok, Prof. Peter Schoenmakers, PhD candidate Gerben van Henten, and postdoc researcher Tijmen Bos in the AutoLC lab at the Van ‘t Hoff Institute for Molecular Sciences. The AutoLC workflow builds on concepts originally introduced by Schoenmakers in 1978, which have now been adapted and extended within a modern, automated framework by the AutoLC team. Schoenmakers, who retired in 2022, was awarded the 2023 LCGC Lifetime Achievement Award." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_HIMS_From_left_to_right_Bob_Pirok_Prof_Peter_Schoenmakers_Ph_D_candidate_Gerben_van_Henten_and_postdoc_researcher_Tijmen_Bos_in_the_Auto_LC_lab_at_the_Van_t_Hoff_Institute_for_Molecular_Sciences_a4fe9bc6f7.jpg 245w," sizes="100vw" width="700" height="425">He is especially grateful to his students who continuously challenge assumptions and push the technology further. “They show why research and education belong together”, he says. “In fact, education is central to how I approach research. Many of the ideas behind AutoLC grew directly from discussions with students, in the lab, in courses, or while trying to explain complex concepts in a clear and accessible way. Seeing students grow into independent scientists, capable of questioning methods and building new ones, is one of the most rewarding aspects of my work.”&nbsp;<blockquote><h5>About Bob Pirok</h5>Bob Pirok (Den Helder, 1987) completed his MSc in analytical chemistry at the University of Amsterdam, followed by doctoral research conducted in close collaboration with industrial partners including Shell, DSM, and Heineken. After earning his PhD in 2019 with Prof. Peter Schoenmakers, Pirok was appointed tenure-track assistant professor at the Van ’t Hoff Institute for Molecular Sciences. There, he co-founded the Chemometrics and Advanced Separations Team (CAST) and was appointed associate professor in 2025.Pirok is also a visiting researcher at Gustavus Adolphus College in the United States and Stellenbosch University in South Africa. Pirok has received the Shimadzu Young Scientist Award (2015), the Csaba Horváth Young-Scientist Award (HPLC 2017), and the Journal of Chromatography Young-Scientist Award (2018). He is a driving force within the University of Amsterdam’s analytical chemistry programs, where he teaches courses in chemometrics, statistics, and separation science and supervises many MSc and BSc students. Pirok serves on the Early Career Board of Analytical Chemistry and is active in professional networks such as the European Chemistry Thematic Network.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/HIMS_Bob_Pirok_speaking_at_the_Balaton_2025_symposium_in_Siofok_Hungary_in_September_2025_106d7cffb5.jpg" alt="HIMS: Bob Pirok speaking at the Balaton 2025 symposium in Siófok, Hungary, in September 2025" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_HIMS_Bob_Pirok_speaking_at_the_Balaton_2025_symposium_in_Siofok_Hungary_in_September_2025_106d7cffb5.jpg 204w," sizes="100vw" width="857" height="655"></blockquote>

Bob Pirok receives LCGC Emerging Leader award

Join analytical chemist Dr. M. Farooq Wahab from the University of Texas at Arlington as he breaks down the science behind chromatographic peak shapes in this episode of the Concentrating on Chromatography podcast. Perfect for undergraduate chemists and researchers alike, this conversation covers:<ul><li>What makes an ideal chromatographic peak shape and why it matters &nbsp;</li><li>Common reasons your HPLC peaks might show tailing, fronting, or distortion &nbsp;</li><li>Practical tips for diagnosing and troubleshooting peak shape problems &nbsp;</li><li>How to use visual and digital tools (like Excel) to analyze your chromatogram data beyond basic numbers &nbsp;</li><li>The importance of baseline correction, denoising, and signal processing in chromatography &nbsp;</li><li>Advice for students and early researchers aiming to excel in analytical chemistry</li></ul>Dr. Wahab shares lively insights from his research and decades of experience, revealing the underlying physics, chemistry, and engineering behind the peaks you see—and why peaks tell the story of your chromatography.Whether new to HPLC or looking to deepen your understanding, this episode demystifies a critical topic that impacts every chromatographer.<h3>Video Transcription</h3>The interview with Dr. M. Farooq Wahab focuses on why chromatographic peak shape matters and how it can be used as a practical diagnostic tool. He explains that the ideal peak is a narrow, symmetric Gaussian shape because it’s easier to detect and integrate reliably, but real peaks often show tailing, fronting, broadening, or splitting, which can compromise quantitation and interpretation.Dr. Wahab groups the main causes of distorted peaks into three buckets: thermodynamic effects (overloading the column’s capacity), kinetic effects (multiple interaction sites causing slow desorption and tailing), and fluid-dynamic/packing effects (non-uniform packed beds leading to fronting, tailing, or split peaks). He also highlights chemical interactions with metal surfaces in LC hardware—especially strong binding of phosphate-containing compounds to iron/steel—that can cause severe tailing or even complete loss of the analyte, sometimes requiring cleaning with chelators like EDTA.He cautions that single-number metrics such as tailing factor or asymmetry are convenient but can hide important details, so analysts should assess the full peak profile, using more advanced evaluations (e.g., Gaussian/derivative-style tests) when needed. For troubleshooting, he recommends “back to basics” benchmarking: run the manufacturer’s QC method on a new column to separate instrument issues from method/column/operator errors.Finally, the discussion broadens to data handling and career advice. Dr. Wahab argues for reproducible, transparent data analysis (sharing code/supporting files) and encourages students to use accessible tools like Excel (and carefully verified AI help) to explore peak diagnostics, denoising, and baseline correction—often best understood via frequency-domain thinking. He closes by advising young scientists to build skills across the “four pillars” of analytical chemistry: chemistry, physics, mathematics, and scientific computation, and to pursue science with passion and realistic expectations.<blockquote>This text has been automatically transcribed from a video presentation using AI technology. It may contain inaccuracies and is not guaranteed to be 100% correct.</blockquote><blockquote><h4>Concentrating on Chromatography Podcast</h4>Dive into the frontiers of chromatography, mass spectrometry, and sample preparation with host David Oliva. Each episode features candid conversations with leading researchers, industry innovators, and passionate scientists who are shaping the future of analytical chemistry. From decoding PFAS detection challenges to exploring the latest in AI-assisted liquid chromatography, this show uncovers practical workflows, sustainability breakthroughs, and the real-world impact of separation science. Whether you’re a chromatographer, lab professional, or researcher you'll discover inspiring content!You can find Concentrating on Chromatography Podcast in podcast apps:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://open.spotify.com/show/1wZg67rCjoGju4yhqxI3tL">Spotify</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podcasts.apple.com/tz/podcast/concentrating-on-chromatography/id1788429185">Apple podcast</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podscan.fm/podcasts/concentrating-on-chromatography">podscan</a></li></ul>and on <a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/@ChromatographyTalk/videos">YouTube channel</a></blockquote>

HPLC Peak Shapes Explained: Why Your Chromatography Peaks Are Not Perfect & How to Fix Them

Article

Video

Scientists

Interview

Science and research

The Czech Advanced Technology and Research Institute (CATRIN) at Palacký University is a cutting-edge scientific hub dedicated to advancing research in the fields of nanotechnology, biotechnology, and biomedicine. At its core, CATRIN boasts outstanding scientific teams, featuring international researchers. We emphasize interdisciplinarity, foster global collaborations, and work to translate our research findings into practical applications.

CATRIN

The University of Amsterdam is one of the largest comprehensive universities in Europe. With some 40,000 students, 6,000 staff, 3,000 PhD candidates, and an annual budget of more than 850 million euros, it is also one of Amsterdam’s biggest employers.

There is an inseparable link between the university and its host city. The freedom and creativity with which Amsterdam has long been associated have worked their way into the fabric of the university. This is a place where individuality, authenticity and diversity are celebrated as sources of stimulation, inspiration and innovation.

Professional and personal development, challenges and collaboration are undertaken in a versatile and multidimensional (inter)national ecosystem with leading stakeholders. Staff at the UvA make a meaningful contribution to uncovering solutions to some of the world’s most significant problems and to developing the next generation of talent.

University of Amsterdam

Organomation, founded in 1959, designs and manufactures high-quality nitrogen evaporators and extraction systems. Known for innovation and durability, their lab instruments are used globally for efficient sample preparation with strong customer support.

Organomation

Agilent Technologies

C&EN

Shimadzu Corporation

Waters Corporation

With the worldwide growth in the oligonucleotide markets, applying the appropriate tools for oligonucleotide analysis and purification is essential. Ion-paired reverse-phase (IP-RP) liquid chromatography involves the use of ion-pairing reagents to form neutral, hydrophobic complexes with charged oligonucleotides, facilitating their retention and separation on reversed phase columns.This presentation introduces the principles and applications of IP-RP in oligonucleotide analysis. It will cover key factors influencing the efficiency of IP-RP methods such as column chemistry, choice of ion-pairing reagent, and mobile phase composition. Additionally, we will discuss method considerations for scaling up your oligonucleotide purification method.<blockquote>Presenter: Melissa Goodlad (Application Engineer, Agilent Technologies, Inc.)Melissa Goodlad is an Application Engineer providing applications assistance and technical support for Agilent’s HPLC columns and consumables. Before joining Agilent, Melissa was completing her PhD in Physical Chemistry at UC Merced studying nanoparticle self-assemblies.</blockquote>

Agilent Technologies: Becoming a Better Chromatographer - Educational Webinar Series

An Introduction to Ion-Paired Reverse-Phase Oligonucleotide Separations: From Analysis to Purification

This presentation introduces the principles and applications of IP-RP in oligonucleotide analysis.

An Introduction to IP-RP Oligonucleotide Separations

Controlling peptide-related impurities is essential to meet regulatory requirements and ensure product quality. The presence of impurities in drug substances and finished products can pose significant immunogenicity risks to patients, potentially leading to drug recalls or warning letters from regulatory bodies.In this webinar, Dr Manoj Metta from the United States Pharmacopeia (USP) will discuss challenges, regulatory expectations and USP solutions to help ensure the quality of peptide therapeutics. Dr Caitlin Hanna from Waters will describe a reverse-phase LC-UV method development case studies for the impurity analysis of fatty-acid modified GLP-1 receptor agonists.Key learning objectives:<ul><li>Understand the key analytical challenges and regulatory expectations for peptide quality assessment</li><li>Learn about USP products and solutions for peptide impurity analysis</li><li>Explore column screening and method development considerations for the analysis of fatty-acid modified GLP-1 receptor agonists</li></ul><blockquote>Presenter: Manoj Kumar Metta, Ph.D. (Principal Scientist, Global Biologics, United States Pharmacopeia (USP))Dr. Manoj Metta is a seasoned Biological Scientist with 21 years of expertise in biologics quality establishment and regulatory sciences. Currently, he serves as Principal Scientist in Global Biologics at the U.S. Pharmacopeia (USP), where he specializes in the quality assessment of Monoclonals, Peptides, and Oligonucleotide drug products. Over his 14+ years at US Pharmacopeia, Dr. Manoj has made significant contributions to compendial sciences, including the development of monographs, reference standards, and general chapters for biologics.<div>He also leads research initiatives focused on developing innovative analytical methods, in vitro characterization techniques, and drug release testing methodologies. He is a USP-approved instructor for Biologics education courses and an international speaker, having delivered talks globally. Additionally, he serves as a quality auditor for Quality Management System (QMS) evaluations in supplier qualification.Dr. Manoj received his Ph.D. in Biotechnology from the Gandhi Institute of Technology and Management.</div>Presenter: Caitlin Hanna, Ph.D. (Senior Scientist, Waters Corporation)<div>Caitlin Hanna is an analytical chemist experienced in sample preparation and LC-UV/MS for biopharmaceutical CQA analysis. She received her PhD in Chemistry from the University of California, Irvine in 2019 and joined Waters Corporation in 2022. Currently, she serves as Senior Scientist in the Bioseparations portfolio. Her work focuses on the development and application of sample prep and chromatography tools for assessing the quality of mAb and peptide biotherapeutics.</div>Moderator: Isabelle Vu Trieu (Pharmaceutical Market Development Manager, Americas, Waters Corporation)Isabelle is a business development professional dedicated to delivering benefits to analytical scientists in the life sciences industry. With over 20 years of experience in providing chromatography and mass spectrometry solutions, Isabelle is particularly interested in helping pharmaceutical scientists achieve the data quality and integrity needed to drive decisions for drug quality, safety and efficacy. Isabelle joined Waters in 2009 and currently manages the development of the pharmaceutical market in the Americas. She holds Masters’ degrees in Chemistry from Columbia University and the University Claude Bernard in Lyon, France as well as a Chemical Engineering degree from Ecole Supérieure de Chimie Physique Electronique in Lyon, France.</blockquote>

Waters Corporation: Solving Problems That Matter - a Waters webinar series featuring USP speakers

Peptide Impurities and GLP-1

We will discuss challenges, regulatory expectations and USP solutions to ensure the quality of peptide therapeutics and describe a RP LC-UV method development.

<h4>PFAS in Focus</h4>Welcome to the PFAS in Focus, a comprehensive and exclusive 10-parts webinar series sponsored by Shimadzu, covering the basics and beyond about the analysis of Per- and Polyfluoroalkyl Substances (PFAS) in the environment. In these five webinars, our experts will demonstrate the suitability of various analytical techniques, such as LCMS, GCMS, CIC, and QTOF, for PFAS testing.Join our experts, live or on-demand after the original air date, to demystify the challenges of PFAS analysis and gain the insights you need to:<ul><li>Manage PFAS contamination in your laboratory.</li><li>Master standardized methods for PFAS testing.</li><li>Discover new analytical workflows to maximize the performance of your instruments (LC-MS/MS, GCMS, CIC, QTOF) for PFAS analysis.</li></ul><h5>Who should attend:</h5><ul><li>Environmental industry professionals and academics currently working on PFAS analysis or looking to establish the application in their labs.</li><li>Representatives from drinking and wastewater utilities.</li><li>LC–MS users from any field interested in expanding their applications to include PFAS testing.</li></ul><h4>Part 05: Ask Us Anything About the Analysis of PFAS</h4>As closing event of the PFAS In Focus webinar series, we will host a live panel discussion. Top experts in the field will provide their perspectives and answer your questions about PFAS testing in diverse environmental samples (water, soil, tissue…).&nbsp;<a target="_blank" rel="noopener noreferrer" href="https://share.hsforms.com/1LXbA9M17S1WNBHvxGUCB3w4t3j7">Submit your questions in advance here by April 3rd, 2025. </a>Or be ready to submit them during the live webinar on April 17th, 2025. Do not miss to get your questions answered and become the PFAS expert in your lab.We will host a Q&amp;A session after the presentation to address any questions or comments.<blockquote>Presenter: Ruth Marfil-Vega, PhD (Sr Market Manager – Environmental, Shimadzu Scientific Instruments)Dr. Ruth Marfil-Vega has 20 years of expertise in environmental chemistry and engineering in the US and Europe. She has worked with the EPA and the utilities industry to design and execute comprehensive solutions for addressing new environmental and water quality issues, including PFAS, regulated and unregulated DBPs, and other emerging contaminants. Since Ruth joined Shimadzu five years ago, she has continued to work with environmental stakeholders to ensure that analytical instrumentation and workflows support their success. She earned a BSc in Chemistry from the University of Valladolid (Spain) and a PhD in Environmental Science and Engineering from the University of Cincinnati.Panelists: Top experts in the field will provide their perspectives and answer your questions about PFAS testing. Pannelists to be announced.</blockquote>

Ask Us Anything About the Analysis of PFAS

As closing event of the PFAS In Focus webinar series, we will host a live panel discussion. 

Nitrosamines have been the compounds of interest for the pharmaceutical industry in recent years due to the mutagenic nature of these impurities. This all started with one nitrosamine impurity N-Nitroso dimethylamine (NDMA) and eventually the list expanded to many nitrosamines in various drug substances and drug products.&nbsp;More recently nitroso-drug substance-related impurities (NDSRI) became the major concern for the industry. As per regulations, any possibility for the formation of Nitroso impurity in the synthetic route or the manufacturing process of the drug substance must be evaluated, and steps must be taken to identify, quantify and minimize/eliminate such impurities. So, the presence of robust methods for the detection and quantitation of such impurities is the need of analytical laboratories. By attending this session, you will understand that the discussion will focus on helping companies getting started in their journey with nitrosamines. It will cover the steps companies need to take to ensure they have a sufficient nitrosamines risk assessment.<blockquote>Presenter: Danita Broyles (Harmony Biosciences)is a native of Clarksdale, MS. She received her B.S. in Chemistry from Rust College and a dual degree M.S. in Biomedical Engineering from the University of Memphis, and the University of TN-Memphis Health Science Center. Danita has an extensive career in the pharmaceutical industry where she tested and released raw materials, performed analytical method validations/transfers, and led compendial compliance and advocacy initiatives throughout her career. Danita is currently the Director of Quality Assurance – CAMS at Harmony Biosciences. She leads a group that specialized in all things Compendial, Analytical, Microbiology, Stability, and Special Project related at Harmony Biosciences. Danita is Co-Chairperson of the Mid-West Compendial Discussion Group, Treasurer of the New Jersey Pharmaceutical Quality Control Association, and she Co-Chairs the USP Stakeholder Engagement Planning Committee. Danita also serves on the USP’s Nominating Committee for the Council of Experts for the 2025-2030 cycle. Danita is a well sought after speaker who has presented a numerous conferences and events throughout her career.Presenter: Chander Mani (Field Technical Specialist-LC Columns, Agilent Technologies, Inc.)Mr. Chander Mani holds a Master’s degree in Chemistry and began his career at Panacea Biotec in the Analytical &amp; Bioanalytical department of new drug discovery research. There, he specialized in method development for analytical and bioanalytical analysis, as well as ADME/DMPK-related studies. He later joined Bureau Veritas, where he developed multiple LC-MS-based methods for analyzing textiles and environmental analytes of interest. For over 12 years at Agilent, Chander has been actively involved in providing LC and LC-MS application support across pharmaceuticals, food safety, and environmental applications in various roles. Recently, he has focused extensively on Nitrosamine analysis in pharmaceuticals, utilizing both LCTQ and LCQTOF platforms, and has published multiple application notes. In his current role as a Technical Specialist for LC and GPC columns, he collaborates closely with customers across the US and Canada.</blockquote>

Agilent Technologies: Navigation Pharma Regulations: Insight and Innovations

Navigating Nitrosamines – Back to Basics

This session will help companies begin their journey with nitrosamines, covering key steps to ensure a sufficient nitrosamines risk assessment.

Advancing Food Safety &amp; Quality with LC/MSEnsuring food safety and quality is more critical than ever, with increasing regulatory scrutiny, emerging contaminants, and the need for higher sensitivity and efficiency in food testing workflows. Liquid Chromatography-Mass Spectrometry (LC/MS) plays a pivotal role in detecting contaminants, verifying authenticity, and ensuring compliance with evolving global food safety standards. However, laboratories often face significant challenges in method development, sample preparation, troubleshooting, and regulatory adherence.<h4>What This Discussion Will Address</h4>In this exclusive virtual Panel Discussion, our experts in food markets, workflows, analytical chemistry, and instrumentation will provide insights into:<ul><li>Emerging trends in food safety testing and how evolving regulations impact laboratories</li><li>Government Initiatives &amp; Funding, emerging opportunities</li><li>Method development challenges in detecting contaminants like pesticides, antibiotics, PFAS, mycotoxins, and other food residues</li><li>Best practices for sample preparation and selecting the right chemistries for accurate and reproducible results</li><li>Troubleshooting common LC/MS challenges to improve efficiency and minimize downtime</li><li>Strategies for improving sensitivity, throughput, and compliance in routine food testing workflows</li></ul>Have specific challenges in your LC/MS food testing workflows? Submit your questions during registration, and our expert panel will address them during the discussion. &nbsp;<blockquote>Presenter: Mr. Rahul Sharma (Sales Development Manager, Food and Environmental Markets, Agilent Technologies India Pvt. Ltd.)Mr. Rahul Sharma is the Market Development Manager for Food and Environmental Markets at Agilent. He is a member of Agilent’s President’s Club and has received numerous awards for sales excellence during his two-decade-long career in the Life Sciences and Applied Markets. In his current role, he drives strategic initiatives and oversees business across agriculture, food, and environmental markets, aligning with India’s growth plan. Rahul holds a postgraduate degree in biotechnology and has completed an executive management program from IIM Kolkata.Presenter:&nbsp;Dr. Prasanth Joseph (Application Engineer - LC/MS, Agilent Technologies India Pvt. Ltd.)Dr. Prasanth is a seasoned professional in analytical instrumentation, specializing in small molecule applications. With 19 years of experience, he joined Agilent in 2015 as an Application Engineer for LC-MS/MS. He holds a Ph.D. in Environmental Science from Bharathiar University, India, and a master’s degree in business administration from the University of Buckingham, UK. Prasanth has extensive expertise in developing analytical methods for genotoxic impurities, extractables and leachables in pharma and food packaging, and conducting bioavailability and bioequivalence studies. His sk ills also include the analysis of phytochemicals, food residue screening, and contaminants in environmental samples.Presenter:&nbsp;Mr. Vikrant Goel (Application Scientist, Agilent Technologies India Pvt. Ltd.)Vikrant comes with an extensive 19 years of experience working in QA/QC, R&amp;D and Analytical roles and an expert in various LC/MS technologies. His solution-based approach has been well accepted among LC/MS fraternity from Pharma and Applied market segments, since 2004. He holds an M.tech in Biotechnology, PG Dip in Bioinformatics &amp; B. Pharm. He joined Agilent in 2010, as a Product specialist for LC/MS, after having worked with ILS Bioservices &amp; LabIndia Instruments. His passion towards solution, brought him back to the Application role, 6 years ago.Presenter:&nbsp;Dr. Ramaprasad Ganni (Technical Support Specialist, Agilent Technologies India Pvt. Ltd.)Dr. Ramprasad has 21 years of experience in the field of Chromatography and Column chemistries. Worked for Elsevier GmbH; Germany, and Millipore India Pvt, Ltd. Presently working with Agilent technologies; India, since 2008 in Chemistries and Supplies division. Responsible for Workflow solutions development, providing technical support, and trainings for various industries of Food, Pharma, Petroleum, Bio-technology. Experienced in developing applications, LC and GC column chemistries and technologies, Sample preparation techniques, method developments and troubleshooting the problems of various chromatography technologies such as LC, GC, Mass Spectrometry, GPC/SEC, and Preparative LC.Presenter:&nbsp;Mr. Siddharth Khurana (Customer Solution Support - LC/MS, Agilent Technologies India Pvt. Ltd.)Siddharth Khurana is a Postgraduate in Pharmacy and comes with 15+ years of diversified experience in Pharma, Application &amp; Service Support for LCMS. For, the past 4 years, he has been working as a Field Service Engineer for PAN India and looking for LCMS products in India. Previously he had worked with Pharmaceutical R&amp;D as a Senior Research Scientist in Fortis Clinical Research &amp; Jubilant Generics Ltd.</blockquote>

Agilent Technologies: LC/MS Expert Forum Panel Discussion

LC/MS Expert Forum Panel Discussion

In this webinar, experts will provide insights into emerging trends in food safety testing and how evolving regulations impact laboratories.

<div><div>The random appearance of unknown peaks (ghost peaks), contaminant peaks, loss of sensitivity or lack of reproducibility are not uncommon in chromatography. Determining the root cause of these issues can be time-consuming and difficult to troubleshoot. In many cases, the root cause is determined to be the sample vials.&nbsp;In this webinar we’ll delve into the critical role of chemically tested sample vials, ensuring accurate and reliable analytical outcomes. Discover how seemingly minor details—such as vial septum material, dimensions, and the glass surface can significantly impact your results. Our experts will guide you through real-world cases where choosing the right vial made all the difference.<h4>Here’s what you’ll learn:</h4><ul><li>Understand the vial characteristics that directly influence your analytical data.&nbsp;</li><li>Explore Waters’ range of sample vials designed to address common challenges.&nbsp;</li><li>Learn practical tips for diagnosing and preventing vial-related issues in chromatography.&nbsp;</li></ul><blockquote>Presenter: Markus Wanninger (Principal Product Manager, Waters Corporation)Markus is the principal product manager of sample vials and plates. He has a degree in chemical engineering and long-standing experience in the pharmaceutical industry. Markus has a keen understanding of the needs of analytical HPLC laboratories, and the controls required to have certainty in results and staying in compliance. The drive to control and optimize processes enabled the Markus and the vials team to drive continuous improvement of product lines to meet the demands of todays’ laboratories. Outside his professional life Markus is a passionate photographer and an inspiring chef and pitmaster.Presenter: Nikunj Tanna (Principal Scientist, Waters Corporation)Nikunj Tanna is a Principal Scientist at Waters Corporation who is passionate about meeting people, making connections, and learning from every conversation. His role at Waters focuses on complete workflow solutions for quantitation of small and large molecules. These end-to-end workflows include automation, novel sample preparation and chromatographic separation approaches, followed by detection using TQ and/or HRMS platforms. In his current role, he has particular emphasis on sample preparation and automation for bioanalysis, ADME and DMPK applications. In previously roles, he lead a clinical diagnostics team at Berg LLC developing bioanalytical methods for drug candidates. He graduated with a BS in Biotechnology and MS in Bioanalytical Sciences from the University of Mumbai, and MS in Pharmaceutical Sciences from Northeastern University.</blockquote></div></div>

Waters Corporation: Are your sample vials causing problems in your HPLC analysis?

Are your sample vials causing problems in your HPLC analysis?

Discover how seemingly minor details—such as vial septum material, dimensions, and the glass surface can significantly impact your results. 

Are your sample vials causing problems in your HPLC analysis

Maintaining water purity in ultra-pure water (UPW) systems, pressurized water reactors (PWR), and steam generation is a constant challenge. Even trace contaminants can lead to corrosion and costly downtime. Detecting these impurities quickly and at ultra-low levels is critical to maintaining performance and preventing operational disruptions. Ion chromatography (IC) provides the precision needed for this level of detection, delivering high-sensitivity trace analysis to identify contaminants and keep water chemistry within strict operational limits.What if you could move from periodic lab testing to continuous monitoring? This shift enhances water quality control, minimizes manual intervention, and improves overall process performance. Semiconductors, nuclear power plants, and refineries rely on online trace analysis to prevent failures and optimize operations. Join us as we explore how integrating trace analysis from benchtop to process monitoring maximizes system integrity. Learn best practices for implementing online ion chromatography and discover how real-time data can improve decision-making and operational efficiency.<div>Key learnings objectives:<ul><li>Learn how ion chromatography enables precise trace analysis for monitoring water quality in UPW, PWR, and steam generation systems.</li><li>Understand how techniques from benchtop systems can be applied to process analytical technology for real-time water quality control.</li><li>Gain insights into integrating trace analysis into both lab and process environments for reliable water quality management.</li></ul>Who Should Attend:<ul><li>Process Engineers looking to integrate advanced trace analysis techniques into operational processes for real-time monitoring</li><li>Quality Control Managers responsible for maintaining product standards and minimizing defects</li><li>Production Managers seeking to enhance efficiency and reduce production costs</li><li>Plant Managers overseeing the overall production process and quality control</li><li>Sustainability and Operations Managers tasked with implementing sustainability practices within their organizations and overseeing the day-to-day operations</li><li>R&amp;D Scientists developing new methods and technologies for improving water quality monitoring and trace analysis in industrial settings</li></ul><blockquote>Presenter: Andrew Schmidt (Nuclear Chemist, Florida Power &amp; Light)Presenter:&nbsp;Dariana Martinez (Product Applications Specialist, Process Wet Chemistry, Metrohm USA)Presenter:&nbsp;Shibu Paul, Ph.D. (Product Specialist, Ion Chromatography, Metrohm USA)</blockquote></div>

Metrohm: Bridging Lab and Process Monitoring for Real-Time Water Quality Insights

Bridging Lab and Process Monitoring for Real-Time Water Quality Insights

Learn how ion chromatography enables precise trace analysis for monitoring water quality in UPW, PWR, and steam generation systems.

Real-Time Water Insights: Lab & Process Connected

Discover the latest innovations in biopharma with a focus on monoclonal antibody (mAb) characterization. This session highlights how Shimadzu’s advanced LCMS-9050 Q-TOF and Protein Metrics software deliver precise analysis of complex biomolecules. Learn how high-resolution mass spectrometry (HRMS) paired with optimized data processing can effectively deliver identification and quantification of Critical Quality Attributes (CQAs) including intact mass and post-translational modifications (PTMs).Gain actionable insights into our end-to-end workflow solution—from best practices in sample preparation to selecting the right columns and consumables—designed to optimize analytical accuracy and reproducibility. Whether in early discovery or late-stage processes, this session provides essential strategies to meet the evolving demands of mAb analysis to advance your biopharmaceutical analysis.<h5>Learning Objectives:</h5><ul><li>Understand the principles and applications of monoclonal antibody (mAb) characterization using Shimadzu’s Q-TOF LCMS-9050</li><li>Explore how Protein Metrics software streamlines data processing in biopharmaceutical analysis</li><li>Gain insights into an end-to-end workflow, covering sample preparation, column selection, and consumables to ensure reproducibility and high-quality results across all development stages</li></ul><blockquote>Presenter: Sheldon Gao (Customer Success Scientist, Protein Metrics)Sheldon Gao, who holds a master’s degree from China Pharmaceutical University specializing in pharmaceutical analysis and protein racemization, has been a Customer Success Scientist at Protein Metrics since 2022. In this role, he provides technical expertise and support to customers across China and the APAC region. Prior to this, Sheldon worked at Merck, where he focused on developing LC-MS/MS methods and protein characterization. Today, he will introduce Byos, highlighting its core features and showcasing its ability to streamline protein characterization data processing efficiently.Presenter:&nbsp;Shannie Tay (Senior Application Specialist (LCMS) Shimadzu (Asia Pacific) Pte Ltd)Shannie Tay is a Senior Application Specialist at Shimadzu (Asia Pacific) Pte Ltd, bringing a wealth of experience in LCMS platforms and a strong background in the biopharmaceutical industry. Her expertise in mAb characterization, quality control, and method development has been honed through positions at leading organizations such as Nestlé NQAC, CellVec Pte Ltd, and Tychan Pte Ltd. At Nestlé R&amp;D, she served as a subject master coach for LCMS triple quad systems, conducting ISO 17025-compliant QC tests. Later, at CellVec and Tychan, Shannie led the QC team, establishing workflows and achieving GMP certification. She authored application notes on mAb characterization, developing an end-to-end workflow with the LCMS-9050 Q-TOF, encompassing sample preparation to data analysis. Widely respected for her ability to create effective analytical workflows and deliver advanced training, Shannie has earned a solid industry reputation for her contributions to QC processes and solutions to complex issues. She will offer valuable insights in today’s discussion.Presenter:&nbsp;Derrick Tan (Senior Application Chemist (Consumables) Shimadzu (Asia Pacific) Pte Ltd)Dr Derrick obtained his PhD in Chemistry from Nanyang Technological University, Singapore.With over 7 years of extensive research experience, Dr Derrick has specialized in various areas, including small molecules, nucleic acids, peptides, and protein synthesis, as well as separation and purification techniques. He joined Shimadzu (Asia Pacific) Pte Ltd in 2021 as an Application Chemist (Consumables).In this role, he is responsible for providing technical support and application expertise for consumables in chromatography and spectroscopy. Portfolio under his care includes a wide range of products, such as LC and GC columns, UV/Vis cuvettes, sample preparation products, sample vials, and other accessories.</blockquote>

Shimadzu: Advanced mAb Characterization With LCMS-9050 QTOF And Byos

Advanced mAb Characterization With LCMS-9050 QTOF And Byos

We will introduce an innovative system with dual analysis capability for both PFAS and cyanotoxins, adhering to EPA Methods 

Reimagine your laboratory experience with Shimadzu’s Living Laboratory, where digital transformation (DX) becomes a reality. &nbsp;As the first AI-assisted automation laboratory, the Living Laboratory seamlessly integrates Shimadzu’s hardware and software into a single ecosystem, delivering a truly next-level laboratory experience. Whether it’s walkaway automation or the ability to work anywhere, the Living Laboratory enables you to work smarter, not harder, while staying at the forefront of innovation. &nbsp;Join us today and experience seamless connectivity, AI-powered capabilities, and paperless workflows—all designed to simplify and optimize various aspects of your lab operations. &nbsp;Discover The Benefits Of Shimadzu’s Living Laboratory<ul><li>AI-Driven Automation: Boost efficiency with eco-friendly, intelligent systems powered by Analytical IntelligenceTM</li><li>Flexibility to Work From Anywhere: Complete control of your lab processes, wherever you are</li><li>Enhanced Productivity: Gain clear insights with advanced software intuitive to all users regardless of skill levels</li></ul>Begin your transformation today. Discover Shimadzu’s Living Laboratory and unleash your full DX capabilities.

Shimadzu: Living Laboratory Unleashed: Your Gateway To Complete DX Capabilities

Living Laboratory Unleashed: Your Gateway To Complete DX Capabilities

Join us today and experience seamless connectivity, AI-powered capabilities, and paperless workflows

Gateway To Complete DX Capabilities

Drug discovery and synthesis are crucial steps in the drug development process and having the proper tools to quickly create and purify drug candidates to inform both upstream and downstream decisions are paramount. However, the field of preparative purification has expanded into many different methodologies depending on your drug modality, that it can be challenging to make sense of the different prep methods. Shimadzu has a wide array of instrumentation that can be tailored to anyone’s preparative purification needs.Attend this webinar on Wednesday, April 16th at 2:00 pm to learn more about our solutions for the preparative purification in the drug discovery space.We will host a Q&amp;A session after the presentation to address any questions or comments.<blockquote>Presenter: Kevin Wons (Market Manager - Pharma/BioPharma, Shimadzu Scientific Instruments)Kevin joined Shimadzu in early 2024 as Market Manager for Pharma/BioPharma. Prior to joining Shimadzu, he spent 6 years at AstraZeneca in the Analytical Sciences Department for product and process characterization for biologics in the AstraZeneca pipeline. Kevin has applications experience with HPLC and LC-MS to do Tryptic Peptide Mapping, Intact Mass Analysis, Subunit Mass Analysis, and Oligosaccharide Profiling. For his last 3 years, he acted as the Glycan Subject Matter Expert (SME) while at AstraZeneca. His work experience also includes Maryland Psychiatric Research Center, where he prepared animal tissue samples such as Brain, Liver, Blood, and Placenta to measure kynurenine pathway metabolites on GC/MS and HPLC. He has a Master’s degree in Professional Studies (MPS) focused on Biotechnology which prepares science professionals to fill management and leadership roles.</blockquote>

Shimadzu: Preparative Purification Solutions in Drug Discovery Synthesis

Preparative Purification Solutions in Drug Discovery Synthesis

Attend this webinar to learn more about our solutions for the preparative purification in the drug discovery space.

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