<h3>A Dedicated Solution for Oligonucleotide Analysis</h3>Oligonucleotides have become key players in modern pharmaceutical and biological research, particularly in the development of highly targeted and personalized therapies. As increasing numbers of oligonucleotide-based drugs enter clinical trials or receive regulatory approval, analytical laboratories face growing demands for both throughput and data quality. These molecules present unique chromatographic challenges due to their long, highly polar structures and subtle variations in nucleobase sequence or functionalization.<h3>Sepapure oliGO – Designed for Oligonucleotide Separations</h3>Selecting the optimal chromatographic approach for oligonucleotide analysis can be complex. Many laboratories rely on ion-pair reversed-phase (IP-RP) chromatography because of its speed, robustness, and compatibility with mass spectrometry. However, commonly used ion-pair reagents can degrade conventional silica-based stationary phases.<a target="_blank" rel="noopener noreferrer" href="https://www.knauer.net/columns-oligonucleotide-columns">Sepapure oliGO</a> addresses this limitation through a hybrid silica matrix combined with specialized surface end-capping, ensuring resistance to aggressive IP-RP reagents. Its functionalized surface enables both strong reversed-phase interactions and controlled ionic contributions, effectively creating a mixed-mode separation mechanism. This design results in improved durability compared with standard mixed-mode columns, making Sepapure oliGO a robust choice for routine oligonucleotide workflows.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_Figure_1_Sepapure_oli_GO_columns_with_laser_etched_column_information_23f545be81.jpg" alt="KNAUER: Figure 1 - Sepapure oliGO columns with laser-etched column information." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_Figure_1_Sepapure_oli_GO_columns_with_laser_etched_column_information_23f545be81.jpg 223w," sizes="100vw" width="1186" height="828"><h3>Method Transfer and Comparative Performance</h3>In collaboration with BianoGMP GmbH, KNAUER’s application team evaluated Sepapure oliGO against a widely used reference column. The study compared oligonucleotides of varying lengths and purities, including a fully thiolated 43-mer DNA. Particular attention was paid to potential interactions between thiolated oligonucleotides and stainless-steel hardware, which have been reported to cause peak tailing.The results demonstrated that direct method transfer between the reference column and Sepapure oliGO was generally feasible without significant adjustment. Chromatographic resolution remained comparable, while retention times were slightly shorter on Sepapure oliGO. Furthermore, the anticipated benefits of expensive bioinert hardware were not confirmed under the tested conditions, suggesting that such effects may primarily influence very fast (U)HPLC separations.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_Figure_2_Overlayed_chromatogram_of_crude_product_of_a_43mer_thiolate_oligonucleotide_7ae9613efd.jpg" alt="KNAUER: Figure 2: Overlayed chromatogram of crude product of a 43mer thiolate oligonucleotide. Light blue - reference column and dark blue – Sepapure oliGO." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_Figure_2_Overlayed_chromatogram_of_crude_product_of_a_43mer_thiolate_oligonucleotide_7ae9613efd.jpg 245w," sizes="100vw" width="1223" height="453"><h3>Low Backpressure for Reliable Operation</h3>Sepapure oliGO can be applied effectively in both HPLC and (U)HPLC workflows. Its low operating backpressure minimizes risks associated with clogging, excessive system wear, and performance deterioration over time. Typical IP-RP separations using 3 µm particles generated pressures around 200 bar, enabling laboratories without ultra-high-pressure systems to perform high-quality oligonucleotide analysis.<h3>Best Practices for Column Performance</h3>To maintain optimal performance, users should observe recommended operating conditions, including a broad pH range of 1.5–10 and temperatures up to 60 °C. Employing a guard column can prevent coarse synthesis by-products from reaching the analytical column. If pressure increases are observed, backflushing at low flow rates can restore performance.When the system is idle, thorough flushing to remove salts is essential. For storage, the column should be kept in a 1:1 mixture of methanol–water or acetonitrile–water. Gradient transitions are recommended when switching between standard RP eluents and IP-RP reagents. Regeneration procedures developed for RP columns are also suitable for Sepapure oliGO.<h3>Beyond Analytical Separations</h3>For large-scale purification, ion-exchange chromatography (AEX) may offer advantages. Scalable preparative systems are available to support purification workflows, ranging from compact laboratory setups to pilot-scale platforms with flow rates up to 800 mL/min. Bioinert configurations can be integrated where required, allowing laboratories to tailor purification solutions to their specific oligonucleotide applications.<blockquote><ul><li>If you're planning to set up or optimize your oligonucleotide workflow, feel free to contact us at sales@knauer.net. Stay tuned for more exciting insights into the Oligonucleotide world in our “Oligos Made Easy” series.</li><li>For more in-depth discussion or questions, reach out to the author at folmert@knauer.net&nbsp;</li></ul></blockquote>

Oligos Made Easy - Part 8: Sepapure oliGO

Visit the LabRulez booth at <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/events/871">analytica 2026</a> in Munich, 24. - 27. March 2026! You can find us in Hall A1, Booth A1.506. At the booth, you will be able to explore live demonstrations of how the LabRulez portals work and see selected analytical instruments from our pre-owned marketplace section.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Lab_Rulez_at_Analytica_2026_Floor_plan_55e1057e03.jpg" alt="LabRulez at Analytica 2026: Hall A1 Floor Plan and Booth Location" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Lab_Rulez_at_Analytica_2026_Floor_plan_55e1057e03.jpg 245w," sizes="100vw" width="1516" height="881"><h3>Would you like to learn how the LabRulez portals work?</h3>➡︎ <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/">LabRulezLCMS</a> ➡︎ <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/">LabRulezGCMS</a> ➡︎ <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/">LabRulezICPMS</a><ul><li>A unique online solution for your marketing</li><li>A targeted audience from the analytical chemistry community</li><li>Modern technologies and a unique concept</li><li>Design optimized for most smart devices – PC, mobile, and tablet</li><li>Advanced statistical tools fully available to users</li></ul><h3>Services Offered</h3><h4>News + Company Updates</h4><ul><li>Publish news related to your instrumentation, applications, services, events, job openings, and more</li><li>News is shared both on our portals and across our social media channels</li></ul><h4>Library – All Documents in One Place</h4><ul><li>Applications, posters, presentations, technical articles, brochures, specifications</li><li>Fast and advanced search capabilities</li><li>Over 32,000 documents currently available in our database</li></ul><h4>Webinars</h4><ul><li>Upcoming and on-demand webinars from the field of analytical chemistry</li><li>More than 5,500 webinars covering chromatography, mass spectrometry, and spectroscopy</li></ul><h4>Careers</h4><ul><li>Targeted job listings in analytical chemistry</li><li>Clear filtering by specialization or location</li><li>Increased visibility for job postings</li></ul><h4>Companies</h4><ul><li>Company profile with key information and contacts</li><li>Integration of all your activities on our portal: News, Library documents, Webinars, Upcoming Events, Careers, and mentions by partners or customers</li><li>Connection to your Products listed on LabRulez portals</li></ul><h4>Products and Services</h4><ul><li>Comprehensive overview of instrumental techniques and services</li><li>Targeting the analytical chemistry community and customers in the growing online environment</li></ul><h4>Marketplace</h4><ul><li>Buying and selling pre-owned analytical equipment</li><li>We purchase analytical instrumentation of all brands and ages</li><li>Sell your equipment through LabRulez</li><li>Request and purchase complete systems, modules, or spare parts with warranty and service</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Lab_Rulez_at_analytica_2026_bazar_7edf4a0872.jpg" alt="LabRulez at analytica 2026" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Lab_Rulez_at_analytica_2026_bazar_7edf4a0872.jpg 88w," sizes="100vw" width="1600" height="2844"><h3>What Will Be on Display at Our Booth?</h3>Come and explore selected spare parts and modules from our marketplace section. These include both new, tested, and pre-owned items.<h4><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/bazaar">LabRulezLCMS Marketplace</a></h4>Spare parts for LC/MS:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/bazaar?category=378">Vacuum turbo pumps for LC/MS</a></li></ul>Spare parts for HPLC:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/bazaar?category=397">Degassers for HPLC/UHPLC</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/bazaar?category=368&amp;search=valve">Automatic valves for HPLC</a></li><li>HPLC components for Agilent 1100, 1200, and 1260 Infinity II series</li></ul>Consumables:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/bazaar?category=377">HPLC lamps</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/bazaar?category=48">HPLC columns</a></li></ul><h4><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar">LabRulezGCMS Marketplace</a></h4>Spare parts for GC/MS:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar?category=367&amp;search=turbo">Turbo pumps for GC/MS</a></li></ul>Spare parts for GC:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar?category=366&amp;search=EPC">EPC modules</a></li></ul>Sample injection<ul><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar/432">Autosampler 7693A for GC</a></li></ul>Consumables:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar?category=7">GC columns </a>and selected accessories</li></ul>

LabRulez at analytica 2026

News from LabRulezLCMS Library - Week 13, 2026

Article

Product

Events

Application

Science and research

Poster

Everything from the world of analytical chemistry in one place. We connect people in solving their problems. At Labrulez you will find all the necessary information easily, quickly and clearly. Stop searching and start finding.

LabRulez

Based in Berlin, KNAUER is a medium-sized, owner-managed company that has been serving the sciences since 1962. We develop and manufacture scientific instruments of superior quality for liquid chromatography, including: Analytical HPLC/UHPLC, Preparative HPLC, Fast protein liquid chromatography (FPLC), Multi-column chromatography/Simulated moving bed (SMB) chromatography. High pressure dosing, in-line detection systems, and osmometry are additional business areas.

KNAUER

Metrohm

The Analytical Scientist

Thermo Fisher Scientific

C&EN

We live in a world of routine, familiarity and comfort. Anything outside of that is scary. It’s not often that we step outside of our comfort zones. Let’s be curious and take a step to the wild side of chromatography with the familiarity that we seek such as HPLC and GC, where we find out more than just counterions. Exploring the world of impurities whether they are organics or metal species, with simple changes and utilizing different detection can help solve many analytical challenges.
Who should attend?
Pharma, Chromatography, MS customers, Lab scientists and Lab managers
What you will learn:
<ul>
<li>The capability of ion chromatography to help solve analytical challenges</li>
<li>How to apply ion chromatography at different stages of drug development</li>
<li>Preventative and troubleshooting drug development with ion chromatography for impurities</li>
</ul>
<blockquote>
Presenter: Wai-Chi Man (Product Marketing Manager, Thermo Fisher Scientific)
</blockquote>
<blockquote>
Wai-Chi has specialized in ion chromatography (IC) since 1989, with over 36 years of experience in analytical chemistry in a wide variety of techniques and industries. Her work at Thermo Fisher Scientific has supported a wide range of customers from various industries, providing IC support in method development, troubleshooting, sample preparation, training, seminars, events, and workshops.
</blockquote>

Thermo Fisher Scientific: How ion chromatography plays a vital role in drug development

How ion chromatography plays a vital role in drug development

How to apply ion chromatography at different stages of drug development. Preventative and troubleshooting drug development.

How ion chromatography plays a role in drug development

This year we invite you to ignite your mind to Be Curious about what Ion chromatography (IC) can do with its versatility in many detections across the IC application spectrum to improve your workflows and solve challenges.
During this three day virtual event, learn from a panel of experts how the latest IC applications are helping colleagues achieve breakthroughs, and walk away with valuable information on how advancements in IC can increase laboratory analytical capabilities. 
Although each day is convenient for a specific region, you can attend any session on any day. All sessions and workshops will be available for on-demand viewing after the event concludes.
<h3>Day 3 Agenda | April 20 | Asia Pacific</h3>
Expand the world of electrochemistry applications and IC hyphenation with high-resolution mass spectrometry and understand how Inductively Coupled Plasma Spectrometry can speciate isotopes while simplifying Pharmacopeia QC analysis and keeping your IC in top-notch condition.
<h5>11:00 AM SGT: Opening Plenary: Electrochemical Detection and Its Application in Ion Chromatography</h5>
<ul>
<li>Yan Liu (Thermo Fisher Scientific, IC/SP R&amp;D, Sunnyvale)</li>
</ul>
<h5>12:00 PM SGT: Application of Anion Chromatography Coupled High-Resolution Mass Spectrometry to Increase Cellular Metabolite Coverage</h5>
<ul>
<li>Vinzenz Hofferek (McConville Lab, Department of Biochemistry and Pharmacology)</li>
</ul>
<h5>1:00 PM SGT: Analysis of Anhydrosugars and Xylooligosaccharides by Ion Chromatography with Electrospray Lithium Cationisation-Triple Quadrupole Tandem Mass Spectrometry</h5>
<ul>
<li>Dr. Estrella Sanz Rodriguez (Natural Products Analysis, Australian Centre for Research on Separation Science (ACROSS), University of Tasmania)</li>
</ul>
<h5>2:00 PM SGT: You Gotta Keep ‘Em Separated: Novel IC Applications for Subsequent Isotopic Analyses by Rapid and/or Hyphenated Techniques</h5>
<ul>
<li>Dr. Brandon Mahan (College of Science and Engineering, James Cook University)</li>
<li>Grace Manestar (IsoTropics PhD Candidate)</li>
</ul>
<h5>3:00 PM SGT: Use of Ion Chromatography in Pharmaceutical Quality Control</h5>
<ul>
<li>Catherine Frankis and Stella Planou (Reading Scientific Services Ltd., Reading Science Centre, Whiteknights Campus)</li>
</ul>
<h5>4:00 PM SGT: Tips on Keeping Your Ion Chromatography in Top-Notch Condition</h5>
<ul>
<li>Ryan Ong (Thermo Fisher Scientific, IC/SP Application Sales Support, Singapore)</li>
</ul>

Thermo Fisher Scientific: IC Symposium 2023

IC Symposium 2023 - Day 3

Join us for the 2023 Global IC Symposium! Day 3 | Asia Pacific.

This meeting covers the latest trends and techniques to meet current water and environmental testing demands for emerging contaminants and evolving regulations. Our guest speakers from the water industry and environmental research and testing laboratories will share their expertise on their latest work, analytical workflows, and automation.
Join us and discover valuable insights to maximise testing productivity and instrument uptime, simplify workflows and standardise data workup.
<h3>June 27 (Day 1) Emerging contaminants</h3>
This session will explore PFAS, microplastics, untargeted screening, automation and sample preparation.
Attend the whole day or selected presentations only.
<h5>10:00 Online access opens (Streaming begins 09:30 BST/10:30 CEST)</h5>
<h5>10:30 Opening of the event, welcome and introduction</h5>
<ul>
<li>Presenter: Jeff Stubbs (Thermo Fisher Scientific)</li>
</ul>
<h5>10:50 Screening of unknowns using Thermo Scientific Orbitrap MS and Thermo Scientific Compound Discoverer software</h5>
<ul>
<li>Presenter: Janine Elliot (Scottish Environment Protection Agency)</li>
</ul>
<h5>11:20 Biotoxins, seafood safety and mass spectrometry</h5>
<ul>
<li>Presenter: Ben Maskrey (Centre of Environment, Fisheries and Aquaculture Science)</li>
</ul>
<h5>11:50 Determination of microplastics with pyrolysis and GC-MS</h5>
<ul>
<li>Presenter: Dr. Michael Soll (Frontier Lab Europe)</li>
</ul>
<h5>12:20 Break</h5>
<h5>12:40 What combustion ion chromatography sum parameter analysis can do for the analysis of PFAS</h5>
<ul>
<li>Presenter: Dr. Lewis Mark (A1-envirosciences Limited)</li>
</ul>
<h5>13:10 Use of Thermo Scientific Exploris 120 Orbitrap HRAM-LC-MS for the analysis of 47 PFAS compounds in UK waters</h5>
<ul>
<li>Presenter: John Quick (ALS Environmental Ltd.)</li>
</ul>
<h5>13:40 Workshop - new untargeted PFAS analysis workflow capabilities within Compound Discoverer software</h5>
<ul>
<li>Presenter: Frans Schoutsen (Thermo Fisher Scientific)</li>
</ul>
<h5>14:10 Break</h5>
<h5>15:10 Starting your voyage into PFAS? Tools and protocols to succeed</h5>
<ul>
<li>Presenter: Ed George (Thermo Fisher Scientific)</li>
</ul>
<h5>16:10 Workshop - new approaches in performing automation by GC (and LC)</h5>
<ul>
<li>Presenter: Dan Carrier (Thermo Fisher Scientific)</li>
</ul>
<h5>16:30 Closing of the live streaming event</h5>

Thermo Scientific: Water & Environmental Analysis User Meeting - Day 1

Water & Environmental Analysis User Meeting - Day 1

Streaming live from our Demo Centre in Hemel Hempstead | Join the complete event or the presentations of your choice only.

This meeting covers the latest trends and techniques to meet current water and environmental testing demands for emerging contaminants and evolving regulations. Our guest speakers from the water industry and environmental research and testing laboratories will share their expertise on their latest work, analytical workflows, and automation.
Join us and discover valuable insights to maximise testing productivity and instrument uptime, simplify workflows and standardise data workup.
<h3>June 28 (Day 2) – Evolving regulations</h3>
This session will explore disinfection by-products, haloacetic acids, heavy metals, volatiles/semi-volatiles analysis.
Attend the whole day or selected presentations only.
<h5>10:00 Online access opens (Streaming begins 09:30 BST/10:30 CEST)</h5>
<h5>10:30 Opening of the event, welcome and introduction</h5>
<ul>
<li>Presenter: Ed George (Thermo Fisher Scientific)</li>
</ul>
<h5>10:50 Beyond compliance - use of the Orbitrap Exploris 120 HRAM-LC-MS for the monitoring of catchments</h5>
<ul>
<li>Presenter: Mark Collins (Northern Ireland Water)</li>
</ul>
<h5>11:20 Utilizing IC-MS/MS for the analysis of halo acetic acids and disinfection by products in drinking water</h5>
<ul>
<li>Presenter: Chris Pegg (Anglian Water)</li>
</ul>
<h5>11:50 GC-MS analysis of environmental samples using automated sample preparation</h5>
<ul>
<li>Presenter: John Quick (ALS Environmental Ltd.)</li>
</ul>
<h5>12:20 Break</h5>
<h5>12:40 Development of an ion chromatography method with EC and MS detection for the analysis of bromide and the disinfection by products bromate, chlorate and chlorite</h5>
<ul>
<li>Presenter: Joseph Scott (Affinity Water)</li>
</ul>
<h5>13:10 High throughput nutrients analysis - developing methodologies for environmental and wastewater matrices</h5>
<ul>
<li>Presenter: Red Godwin (Thermo Fisher Scientific)</li>
</ul>
<h5>13:40 Performing the analysis of trace metals in environmental samples via ICP and ICP-MS</h5>
<ul>
<li>Presenter: Trudy McMurray (Northern Ireland Environment Agency)</li>
</ul>
<h5>14:15 Closing of the live streaming event</h5>

Thermo Scientific: Water & Environmental Analysis User Meeting - Day 2

Water & Environmental Analysis User Meeting - Day 2

EPA Draft Method 1621 represents a shift in thinking in how we screen for PFAS and other fluorinated compounds in the environment, giving a better picture of the full scope of contamination. The method uses combustion ion chromatography (CIC) to determine adsorbable organic fluorine (AOF) in water samples, a non-targeted sum parameter defined by the method itself.
In this webinar, Amelia Paolantonio, from Enthalpy Analytical, will show attendees how she was able to successfully implement this method in her lab. Webinar participants will gain valuable insights into best practices for the method and things to watch out for, such as the importance of cleanliness. Dr. Jay Gandhi, from Metrohm USA, will discuss how to execute a total solution for your fluorine analysis to help you comply with Draft Method 1621. 
Key Learning Objectives:
<ul>
<li>Learn about EPA Draft Method 1621 and its requirements
</li>
<li>Find out the challenges of executing this method and the strategies to overcome them
</li>
<li>Learn how to implement a total solution for complying with the method
</li>
</ul>
Who Should Attend:
<ul>
<li>Environmental lab technicians, analysts, lab managers, and lab directors
</li>
<li>Those interested in learning about new monitoring technologies for PFAS and fluorinated compounds
</li>
</ul>
<blockquote>
Presenter: Amelia Paolantonio (Senior Scientist, Enthalpy Analytical)
</blockquote>
<blockquote>
Presenter: Dr. Jay Gandhi (Vertical Markets Manager, Metrohm USA)
</blockquote>
<blockquote>
Presenter: Catherine Dold (Health &amp; Environment Writer, C&amp;EN Media Group)
</blockquote>

C&EN: The Changing PFAS Landscape: Insights Into EPA Draft Method 1621

The Changing PFAS Landscape: Insights Into EPA Draft Method 1621

EPA Draft Method 1621 represents a shift in thinking in how we screen for PFAS and other fluorinated compounds in the environment

Insights Into EPA Draft Method 1621

Discrete analyzers are robust, easy-to-use, and provide parallel measurement of multiple analytes in as fast as 10 minutes. Compared to traditional wet chemistry techniques, they provide equivalent or better data quality while speeding up the determination process significantly. Adding this automation to one’s laboratory workflow significantly reduces the amount of reagent used and analysts’ bench time. Ion chromatography (IC) is a well-established analytical method that expands the breadth of water analyses by offering distinct capabilities that include ultra-trace level determinations for a broad spectrum of analytes. Thermo Scientific Dionex IC Systems can be tailored to meet specific anion and cation analysis needs providing direct determination of multiple analytes in a single run and the ability to handle challenging sample matrices.
In this webinar, Timothy Traynor, Technical Specialist at Pace Analytical will present comprehensive water analysis workflows utilizing integrated discrete analyzers and Dionex IC systems and discuss their complementary benefits that offer high sensitivity, flexibility, and sample throughput, helping laboratories in Pace’s network to reduce overall cost per test and increase laboratory productivity.
Gary He, Product Marketing Manager, will also discuss the recent advances of Thermo Scientific Gallery Aqua Master Discrete Analyzers that enable more automation and better U.S. EPA compliance.
Dr. Carl Fisher, Product Marketing Manager, will conclude the session by providing a high-level overview of the tailored Thermo Scientific IC solutions that are integral to comprehensive water analysis.
<blockquote>
Presenter: Timothy Traynor (Technical Specialist, Pace Analytical)
</blockquote>
<blockquote>
Timothy Traynor has been a Technical Specialist in Pace’s IDEA Lab since 2019. Prior to his current role, Traynor has worked as a Chemist and a Metals Analyst at Pace, and a Chemist at the North Dakota Department of Health, among others. Traynor has a bachelor’s degree in Chemistry from Concordia College and a master’s degree in Theology from Saint John’s University.
</blockquote>
<blockquote>
Presenter: Gary He (Product Marketing Manager - Gallery Discrete Analyzers, Thermo Fisher Scientific)
</blockquote>
<blockquote>
Currently serving as the Product Marketing Manager for the Gallery discrete analyzers within Thermo Fisher Scientific, Gary is responsible for leading the marketing programs to drive sustainable technology adoption in established applications such as water, nutrient, agricultural, food and beverage analyses, and in new adjacent applications, such as enzyme analysis for food and beverage, animal nutrition, grain processing, home care detergent, and biopharma.
</blockquote>
<blockquote>
Presenter: Carl Fisher (Product Marketing Manager - Ion Chromatography, Thermo Fisher Scientific)
</blockquote>
<blockquote>
In his current role, Carl is the Product Marketing Manager focusing on environmental applications for ion chromatography and sample preparation products . Prior to this, he spent several years as an analytical chemist as a member of the Applications Laboratory team, producing technical and application notes.
</blockquote>

Thermo Scientific: Expanding the breadth of water contaminant determinations with ion chromatography and discrete analysis

Expanding the breadth of water contaminant determinations with ion chromatography and discrete analysis

IC Systems can be tailored to meet anion and cation analysis needs providing direct determination of multiple analytes in a single and challenging matrices.

Water contaminant determinations with ion chromatography

Ion chromatography (IC) is a technique extensively used to analyze water samples from different sources, including drinking water, surface water, and wastewater.
Strict adherence to national or global standardized ion chromatography methods, including ISO, ASTM, and DIN, is critical to guarantee reliable and accurate results. Furthermore, standardization provides a unified analytical method for comparing and evaluating environmental monitoring data sets.
In this webinar, our European Senior Ion Chromatography Expert, Detlef Jensen, will explore the critical role of standardized ion chromatography methods in water contaminant analyses. 
ISO and ASTM IC procedures for the following water contaminants will be covered:
<ul>
<li>Disinfection byproducts e.g., bromate
</li>
<li>Perchlorate
</li>
<li>Chromate
</li>
<li>Cations, e.g., sodium, calcium, and ammonium
</li>
<li>Anions, e.g., chloride, nitrate, and fluoride
</li>
</ul>
Who should attend:
<ul>
<li>Environmental and water testing laboratories 
</li>
<li>Laboratory scientists and technicians testing using IC 
</li>
<li>Water and environmental analytical chemistry laboratory manager 
</li>
<li>Contract testing laboratories
</li>
</ul>
<blockquote>
Presenter: Detlef Jensen (Sr. Application Expert Applied Markets, EMEA, Thermo Fisher Scientific)
</blockquote>
<blockquote>
Detlef holds a PhD in chemistry from the Technical University Berlin/Germany. For 30 years, he covered many positions at Dionex and Thermo Fisher Scientific. He is supporting our users and our team of field experts all over Europe with his deep knowledge of all expects of ion chromatography and its applications
</blockquote>

Thermo Scientific: Overview of standardized IC methods for water analysis

Overview of standardized IC methods for water analysis

Explore the critical role of standardized ion chromatography methods in water contaminant analyses.

This webinar highlights the importance of impurity testing in pharmaceuticals and how ion chromatography can provide excellent sensitivity and selectivity when testing for ionic impurities.
The management and control of pharmaceutical impurities is a matter of great concern and is an important part of drug development and regulatory assessment.
Current regulations and guidelines demand a comprehensive understanding of the impurity profile of pharmaceutical products, as their safety and quality can be impacted by these impurities.
The ICH quality guidelines ICH Q3A and Q3B address questions related to the regulation of impurities in the drug substance and drug product, whereas other ICH quality guidelines address specific types of impurities, such as residual solvents and mutagenic impurities.
This webinar explores the different kinds of impurities that may be present in pharmaceutical products and how ion chromatography (IC) is the analytical tool of choice to meet regulatory authorities’ requirements and in defining effective control strategies.
Learn how ion chromatography can help to automate impurities analysis workflows. Inline sample preparation techniques will also be discussed.
Key takeaways:
<ul>
<li>Understand the origins of impurities in pharmaceuticals and why impurity profiling is important
</li>
<li>Gain insight into the regulations surrounding impurities analysis in pharmaceuticals
</li>
<li>Learn about how ion chromatography makes an ideal technique for the analysis of ionic impurities, offering enhanced sensitivity and selectivity, and helping to automate and simplify workflow.
</li>
</ul>
<blockquote>
Presenter: Daniel Pereira (Senior Scientist, Regulatory Affairs, Hovione)
</blockquote>
<blockquote>
Daniel Pereira has been an analytical scientist at Hovione since 2018 and is currently a Senior Scientist of the chemical characterisation team in the R&amp;D Analytical Development Area. He has extensive expertise in the field of chemical characterisation techniques with focus in several chromatography techniques and in the development and optimisation of analytical methods following AQbD approach. Daniel holds a bachelor´s degree in Pharmacy from University of Rio de Janeiro, Brazil and a MSc in analytical chemistry form Minho University, Portugal.
</blockquote>
<blockquote>
Presenter: Linx Waclaski (IC Product Manager, Metrohm USA)
</blockquote>
<blockquote>
Linx Waclaski is the Product Manager for Ion Chromatography at Metrohm USA, in Riverview, Florida. He has years of experience in multiple chromatographic techniques, including ion chromatography, gas chromatography, liquid chromatography, and mass spectrometry, with extensive experience in R&amp;D and applications development. He has an MS in Forensic Science and a BA in Biochemistry from Duquesne University in Pittsburgh, Pennsylvania, US.
</blockquote>

Metrohm: Analysis of impurities in pharmaceuticals using ion chromatography

Analysis of impurities in pharmaceuticals using ion chromatography

The importance of impurity testing in pharmaceuticals and how ion chromatography can provide excellent sensitivity and selectivity.

Analysis of impurities in pharmaceuticals

Welcome to The Analytical Scientist’s Trends and Challenges in PFAS Analysis forum!
Per- and poly-fluorinated alkyl substances, or PFAS, are a family of synthetic substances used in everyday products, such as stain and grease-repellent coatings and have appeared in almost all foods and drinking water. Toxic at extremely low levels, regulators demand low detection limits, and the list of PFAS compounds under investigation continues to expand. 
We recently asked our readers for their thoughts on the challenges involved in PFAS analysis, whether current methods are up to the task, and what analytical advances may be on the horizon. 
Here, our panel of experts will discuss the survey findings and share their perspectives on the latest trends and best practices in PFAS analysis. 
The event will have three parts: 
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<li>Part I: A discussion of the results of our recent vendor-neutral audience survey (10-15 minutes).
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<li>Part II: Technology/application-focused presentations from each of our speakers (15 minutes each).
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<li>Part III: A chance for you to ask our speakers questions as part of an audience Q&amp;A (15 minutes).
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</ul>
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Presenter: Day Powell (Environmental Application Specialist , Agilent)
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Day has worked for Agilent as an Environmental Specialist for one year. Before this he worked for a major UK Water company (United Utilities) as a senior analyst responsible for developing new methodologies for both LC/MS and GC/MS applications.
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Day has analysed PFAS for several years and helped United Utilities to gain UKAS accreditation for determining 47 PFAS by LC/MS in drinking water using direct injection to address the latest Drinking Water Inspectorate (DWI).
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Presenter: Marcus Chadha (EMEA Applications Specialist Manager, Agilent) Dr. Marcus Chadha has worked for Agilent for seven years where he first worked as an LC/MS Field Application Specialist before moving on to being the EMEA Applications Specialist Manager in 2021.
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In his roles he has collaborated with our Environmental and Food customers, developed new methods, and trained LC/TQ and LC-Q/TOF MS workflows to new and existing customers.
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He now coordinates these activities using his team of GC/MS and LC/MS application specialists. Marcus is also responsible for the market specialisation activities for the environmental market across Europe.
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Presenter: Linx Waclaski (Product Manager for Ion Chromatography, Metrohm USA)
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Linx Waclaski is the Product Manager for Ion Chromatography at Metrohm USA, in Riverview, Florida. He has years of experience in multiple chromatographic techniques, including ion chromatography, gas chromatography, liquid chromatography, and mass spectrometry, with extensive experience in R&amp;D and applications development.
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His chromatography applications experience extends across environmental, food safety, and life sciences industries. He has an M.S. in Forensic Science from Duquesne University.
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Presenter: Ruth Marfil-Vega (Senior Market Manager - Environmental, Shimadzu)
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Dr. Ruth Marfil-Vega has 20 years of expertise in environmental chemistry and engineering in the US and Europe. She has worked with the EPA and the utilities industry to design and execute comprehensive solutions for addressing new environmental and water quality issues, including PFAS, regulated and unregulated DBPs, and other emerging contaminants.
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Since Ruth joined Shimadzu five years ago, she has continued to work with environmental stakeholders to ensure that analytical instrumentation and workflows support their success.
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She earned a BSc in Chemistry from the University of Valladolid (Spain) and a PhD in Environmental Science and Engineering from the University of Cincinnati.
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Agilent Technologies: Trends and Challenges in PFAS Analysis

Trends and Challenges in PFAS Analysis

Survey findings and perspectives on the latest trends and best practices in PFAS analysis.

In this on-demand webinar, Wai-Chi Man, Product Marketing Manager at Thermo Fisher Scientific, discussed the basics of why Ion Chromatography coupled with Mass Spectrometry (IC-MS) can be an added benefit to any High-Performance Liquid Chromatography with Mass Spectrometry (LC-MS), and complimentary to any Hydrophilic Interaction Liquid Chromatography (HILIC) analysis.
You can also expect to:
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<li>Enhance your understanding of the instrument requirements for IC and MS: which one is best for your application of interest.
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<li>Learn how to set up the connectivity or simply switch from IC-MS to LC-MS.
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<li>Explore the switch over from applications such as Polar Pesticides from Anionic to Cationic with one instrument set-up, and how it’s applicable to other applications such as Metabolomics.
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Presenter: Wai-chi Man (Product Marketing Manager, Thermo Fisher Scientific)
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Wai-Chi Man, MRSC has been with Thermo Fisher Scientific since 2011. She started on the application sales support team but is now a product marketing manager. She has specialized in ion chromatography (IC) for more than 33 years, with over 36 years of experience in analytical chemistry in a wide variety of techniques. Before Thermo Fisher Scientific, she spent seven years at Wellcome Research supporting structural elucidation for medicinal chemists using a wide range of analytical instrumentation. Wai-Chi spent a total of 20 years in the pharma industry as part of GlaxoSmith Kline, from research to transferring methods to manufacturing. She worked on and was responsible for many drugs from anti-viral to respiratory in the market today.
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Wai-Chi’s work at Thermo Fisher Scientific has supported a wide range of customers from various industries, providing IC support in method development, troubleshooting, sample preparation, trainings, seminars, events, and workshops. This experience has helped her build greater knowledge, skill and understanding within areas such as IC-MS, IC-ICP-MS, HPAE-PAD analysis, metabolomics, and polar pesticides.
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Thermo Scientific: Back to Basics – IC-MS 

Back to Basics – IC-MS 

The basics of why Ion Chromatography coupled with Mass Spectrometry (IC-MS) can be an added benefit to any High-Performance Liquid Chromatography.

LCMS webinars focusing on IC - page 6