LCMS webinars focusing on Tips & Tricks

The causes of “false positive” and “false negative” derived from both QqQ-MS and HR-MS detection will be discussed.

How to improve your LC-MS/MS assays by investigating the causes of chromatographic variation, the effects of differing methods of compound optimization and the sources of ion suppression.

LC selectivity theory and its parameters. Column phases and expected interactions with five different steroids. Screening 4 phases and how they affect the LC selectivity for a steroid panel.

How column choice affects PFAS selectivity. Learn how modified C18, -Hexyl, Phenyl-Hexyl, and Fluorinated phases affect PFAS selectivity. How using organic modifiers can improve PFAS selectivity.

Primer on Oligonucleotide & chromatographic challenges. Method Development consideration by LC. Mobile phase composition Impact on sensitivity. The impacts on metal cations on LC MS methods for Oligos.

Understanding chromatographic Interactions. Identifying Sytem/method/column related issues. Choosing right mobile phase/column. Proper column washing and storage conditions.

In this talk, Agilent’s LC/MS Regional System Specialists will discuss several topics that will help eliminate the fear factor of LC/MS by providing best practices and troubleshooting tricks and tips.

3 Topics: How to choose different column phases; What kind of LC columns can be a strong method development kit; How to take care of your LC column to extend its lifetime.

In this webinar, we will look at the parameters and considerations for GPC columns and selection.

In this webinar, we will work through troubleshooting strategies to help find the source of the problem.