This compact device saves up to 90% of mobile phase by redirection of the pure solvent to the solvent reservoir during the isocratic HPLC. The device is powered by 5 V DC from computer USB port or power adapter. Working parameters (Threshold and Delay) are set using user friendly software.<blockquote>Price: 635<bdi>&nbsp;€ ex VAT</bdi></blockquote>The UFO Solvent Recycler continuously monitors the output signal of the chromatography detector and displays its current value in the application on computer. A high-resolution analog-to-digital converter provides data for further evaluation in the built-in processor.If the input signal level exceeds a preset value (Threshold), the UFO recycler will redirect the flow to the waste. When the signal drops, the solvent recycler waits for the transport delay and then switches the mobile phase back to the reservoir. An autosampler injection marker connected to the UFO recycler START input can be used to zero the input signal at the time of injection.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/UFO_schema_6a4cdc0ed4/UFO_schema.png" alt="Watrex: Principle and process of mobile phase recycling during isocratic HPLC using the UFO system" width="1348" height="1378"><h3>FEATURES</h3><ul><li>Very compact design</li><li>Simple operation</li></ul><h3>TECHNICAL SPECIFICATION</h3><ul><li>Detector compatibility: compatible with any HPLC detector</li><li>Connection: 1/16″ O.D. tubing, 1/4″-28 flat bottom fittings</li><li>Maximum pressure: 30 p.s.i./0,2 MPa</li><li>Wetted material: PEEK, PTFE</li><li>Input range: +/- 1 V or +/- 100 mV, user selectable</li><li>Computer connection: USB-A</li><li>TTL/contact closure input: configurable (ZERO, start, valve position)</li><li>Power: 5V DC/&lt;100 mA (power supply or computer USB port)</li><li>User interface: PC Windows based software</li></ul><h3>Ordering information:</h3><h5>PN/Component:</h5><ul><li>UFO000-001 UFO™ Solvent Recycler , PEEK version</li><li>UFO000-002 UFO™ Solvent Recycler , PTFE version</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Watrex_UFO_1_01268632dd/Watrex_UFO_1.jpg" alt="Watrex: Introducing Watrex UFO Solvent Recycler." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Watrex_UFO_1_01268632dd/thumbnail_Watrex_UFO_1.jpg 177w," sizes="100vw" width="1310" height="1152"><blockquote><h4>Selected document from Watrex in <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library?mainauthorItems=93">LabRulesLCMS library</a>:</h4><h5><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/Watrex_catalog_2024_ba97395f92.pdf">Watrex product catalog 2024</a></h5><ul><li>HPLC, GPC/SEC, Sample Preparation, LC columns, Consumables</li></ul><h5><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1341">WATREX SYRINGE FILTERS</a></h5><ul><li>Consumables</li></ul><h5><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products?category=48&amp;distributorItems=59&amp;manufacturerItems=93">Watrex HPLC COLUMNS</a></h5><ul><li>Consumables, LC columns</li></ul><h5><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/Watrex_Clean_Water_for_Quality_Results_Rely_on_Our_Water_Systems_dc404f75df.pdf">Clean Water for Quality Results: Rely on Our Water Systems</a></h5><ul><li>Laboratory instruments</li></ul><h5><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/300">Watrex - LSS-205 Liquid Sensing System</a></h5><ul><li>Laboratory instruments, HPLC</li></ul><h5><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/article/4671">8 points on how to care for columns</a></h5><ul><li>Consumables, LC columns</li></ul><h5><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products?category=179&amp;distributorItems=59&amp;manufacturerItems=93">Watrex WATER PURIFICATION SYSTEMS</a></h5><ul><li>Laboratory instruments &nbsp;</li></ul></blockquote>

Introducing Watrex UFO Solvent Recycler

16th Multidimensional Chromatography Workshop (MDCW) - Program

From December 1st to December 31st, 2024, when you purchase any new Mnova license, you'll receive an additional plugin of your choice FREE for 1 year.<blockquote><h5>Check out our tutorial videos for Peak Purity Assessment in LCMS with Mnova MSChrom, Advanced Chemometrics, and BioHOS.</h5><ul><li><a target="_blank" rel="noopener noreferrer" href="https://youtu.be/FkJ43lQrMwI">Peak Purity Assessment for LCMS using MCR mode in Mnova MSChrom</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://youtu.be/nab8pR2RAbE">MCR tool in Mnova chemometric solutions: Advanced Chemometrics and BioHOS</a></li></ul></blockquote>&nbsp;<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Mestrelab_Research_Mestrelab_Holiday_Special_Get_More_from_Mnova_This_December_Buy_1_Get_1_255c1413bd.jpg" alt="Mestrelab Research: Mestrelab Holiday Special - Get More from Mnova This December: Buy 1 - Get 1!" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Mestrelab_Research_Mestrelab_Holiday_Special_Get_More_from_Mnova_This_December_Buy_1_Get_1_255c1413bd.jpg 245w," sizes="100vw" width="1920" height="1080">Whether you're in industry, government, or academia, this limited-time offer is the perfect way to enhance your analysis toolkit with our powerful suite of tools for NMR, LC/GC-MS, and Electronical &amp; Vibrational Spectroscopic techniques. It’s also an excellent choice for exploring our solutions tailored to specific applications, such as <a target="_blank" rel="noopener noreferrer" href="https://bit.ly/3VgxIne">prediction</a>, <a target="_blank" rel="noopener noreferrer" href="https://bit.ly/4eYNRoC">reaction monitoring</a>, <a target="_blank" rel="noopener noreferrer" href="https://bit.ly/49iDUBh">structure elucidation</a> and <a target="_blank" rel="noopener noreferrer" href="https://bit.ly/3CUNxd6">verification</a>, <a target="_blank" rel="noopener noreferrer" href="https://bit.ly/49gfisB">quantification</a> and <a target="_blank" rel="noopener noreferrer" href="https://bit.ly/3Zu3EHs">mixture analysis</a>, <a target="_blank" rel="noopener noreferrer" href="https://bit.ly/3B8Jvx9">screening</a>, <a target="_blank" rel="noopener noreferrer" href="https://bit.ly/3CQKwuv">chemometrics</a>, <a target="_blank" rel="noopener noreferrer" href="https://bit.ly/41ddyOV">database management</a>, and <a target="_blank" rel="noopener noreferrer" href="https://bit.ly/3ZB1aWL">more</a>!<h4>How It Works:</h4><ol><li>Buy any new Mnova license.</li><li>Choose an additional plugin (of equal or lesser value) for free for 1 year.</li><li>Expand your research capabilities with unmatched tools!</li></ol>Don’t wait—claim your offer now!<h4>Offer Details:</h4><ul><li>Valid: December 1–31, 2024</li><li>Exclusions: Mnova Gears and its plugins/bricks, USP-ID, Mnova Web, Mbook.</li><li>Discounts: Cannot be combined with other discounts (except volume discounts).</li></ul>Act now and give yourself the gift of innovation this holiday season.<a target="_blank" rel="noopener noreferrer" href="https://bit.ly/41euuVs">Visit our web store</a> or <a href="mailto:sales@mestrelab.com" target="_blank" rel="noopener noreferrer">contact</a> us directly to claim your offer now!<blockquote><h4>About <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/companies/298">Mestrelab Research</a>:</h4>For two decades, we have provided cutting-edge tools to enhance analytical data processing, analysis, and reporting experience. Today, our comprehensive range of products and solutions extends beyond NMR to include LC/GC-MS and other spectroscopies. These tools empower users to automate routine tasks, streamline workflows, and focus on what truly matters—extracting meaningful insights from their data.</blockquote>

Mestrelab Holiday Special - Get More from Mnova This December: Buy 1 - Get 1!

Software

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Events

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The Multidimensional Chromatography (MDC) Workshop draws experts in this exciting field to share and discuss their research.

The Multidimensional Chromatography (MDC) Workshop

Mestrelab Research is a scientific software company with nearly two decades of expertise, specializing in providing advanced solutions in the field of analytical chemistry. As a fast-growing company, we have doubled in size over the past five years, now boasting over 90 employees spread across headquarters in Santiago de Compostela (Spain), as well as offices in Europe, Asia, and the USA.

Mestrelab Research

WATREX Prague is the distributor and producer of HPLC techniques in the Czech Republic and Slovakia. Main Chromatografic and Related Techniques Supported: LC, GPC, IC, IEC, Automated SPE, LC Columns and special column packings, LC method development, Software development, Laboratory Robots.

Watrex Praha

Separation Science

Agilent Technologies

Phenomenex

Waters Corporation

Forensic Toxicology laboratories analyze a variety of samples which contain impurities. These impurities can lead to puzzling data, dirty instrumentation and interferences if not removed properly. Waters has a series of sample preparation materials to ensure that your samples are clean for injection into your LCMS instrument. It is important to select the appropriate sample preparation technique based off your matrix type, analytes of interest, and level of selectivity. Solid phase extraction (SPE) provides the highest level of selectivity and Waters Oasis HLB products use a water-wettable sorbent leading to high, consistent recoveries for acidic, basic, and neutral compounds in fewer steps. The Oasis product line offers benefits in reduced matrix effects, consistency, instrument up time and column lifetimes, as well as improved assay performance and low variability.
Learning Objectives:
<ul>
<li>Why do we perform Solid-Phase Extraction (SPE) in a forensic toxicology workflow? </li>
<li>How can Waters Oasis SPE products improve my sample recoveries? </li>
<li>How can matrix interferences affect my data if not removed? </li>
<li>How do I know my SPE method was successful?</li>
</ul>
<blockquote>
Presenter: Sarah Olive (Clinical and Forensic Account Manager, Waters Corporation)
</blockquote>
<blockquote>
Sarah Olive is currently a Clinical and Forensic Account Manager in the Waters Clinical Business Unit. Her LCMS career began as a Forensic Toxicologist in the Dallas County Medical Examiner’s office. Previously, she worked as an LCMS Application Specialist assisting laboratories to develop and implement their methods in the Forensic, Clinical, Biopharma, and Environmental markets.
</blockquote>

Waters Corporation: Improve Sample Cleanup in Fewer Steps using Waters Oasis Sample Preparation Products in a Forensic Toxicology Laboratory

Improve Sample Cleanup in Fewer Steps using Waters Oasis Sample Preparation Products in a Forensic Toxicology Laboratory

The Oasis product line offers benefits in reduced matrix effects, consistency, instrument uptime and column lifetimes.

Waters Oasis Sample Preparation in Forensic Toxicology

Key Learning Points:
<ul>
<li>Learn how to approach analyzing for PFAS, it is not rocket science like they made it out to be</li>
<li>Become aware of Sporadic PFAS Contamination</li>
<li>Understand how to identify false positives</li>
<li>Require all analysis quality control and samples to be analyzed in replicates to identify false positives</li>
</ul>
Who Should Attend:
<ul>
<li>Anyone who is new or has used Quechers and needs to have an update and an insight on Quechers method</li>
</ul>
<blockquote>
Presenter: Duilio Romanello (Senior Technical Specialist, Phenomenex)
</blockquote>
<blockquote>
Duilio Romanello graduated with his Bachelors of Science in Pharmaceutical Chemistry and Technology from University of Bologna. Duilio then joined Phenomenex in 2008 as an Inside Technical Sales Consultant becoming Team Leader in Italy for GC/SPE in 2010 and then for the Environmental &amp; Food Team. Since 2016 he has been covering the role of Account Manager for the South of Italy working remotely and acting as GC Specialist. Since November 2023 he is Senior Technical Specialist for the Technical team at Phenomenex.
</blockquote>

Phenomenex: Quechers 101: Background and Updates

Quechers 101: Background and Updates

Learn how to approach analyzing for PFAS, it is not rocket science like they made it out to be

Overview:
Nitrosamines – the current state of play
<ul>
<li>Background.</li>
<li>Potential Sources of Nitrosamines.</li>
<li>Practical Challenges for N-Nitrosamine Analysis.</li>
<li>Sample Preparation Approach for Analysis of N-Nitrosamines in Drug Products.</li>
</ul>
Key Learning:
<ul>
<li>A New SPE Method for for Simultaneous Quantification of 13 N-Nitrosamines in Various Drug Products</li>
</ul>
<blockquote>
Presenter: Dr. Heiko Behr (Senior Business Development Manager, Phenomenex)
</blockquote>

Phenomenex: New SPE Method for Simultaneous Quantification of 13 N-Nitrosamines in Various Drug Products

New SPE Method for Simultaneous Quantification of 13 N-Nitrosamines in Various Drug Products

Sample Preparation Approach for Analysis of N-Nitrosamines in Drug Products.

New SPE Method for 13 N-Nitrosamines in Drug Products

Key Learning Points:
<ul>
<li>Understand the benefit of using SPE than other sample preparation techniques </li>
<li>Learn the basic protocol for SPE method and separation modes</li>
<li>Dig into reverse phase SPE typical protocol, and solid phase extraction media</li>
</ul>
Who Should Attend:
Anyone beginning with solid phase extraction (SPE) technique, or anyone struggling with method sensitivity
<blockquote>
Presenter: Grace Guo (Senior Technical Specialist, Phenomenex)
</blockquote>
<blockquote>
Grace Guo graduated from the Johns Hopkins University with a Master’s degree in Material Science and Engineering. She joined Phenomenex Technical Team in 2017 providing technical support globally. With more than 8 years of experience on SPE, HPLC and GC, she delivered 50+ seminars and webinars globally covering food and environmental, clinical, pharma and biopharma industry. 
</blockquote>

Phenomenex: Solid Phase Extraction Introduction and Theory

Solid Phase Extraction Introduction and Theory

Understand the benefit of using SPE than other sample preparation techniques.

As public awareness and regulations regarding PFAS contamination continue to expand, so does the overall volume of sampling and analysis for PFAS. Currently, the routine analytical approach for PFAS analysis is to first prepare/cleanup/concentrate the sample by Solid Phase Extraction (SPE) and then analyze by LC-MS/MS. Sample preparation by SPE is a very time- and cost-intensive process; considering the drastic expansion of PFAS monitoring that is expected to come with future regulation, a new approach is needed to reduce overall project costs and increase the lab’s ability to provide rapid, actionable results.
Pace has developed and validated a ‘direct injection’ approach for PFAS analysis by LC-MS/MS, similar to the protocols described in EPA 8327 and ASTM D8421 &amp; D8535. This new approach has been employed in two field projects, in which the data were used for guidance on boring and sampling for continued project analyses. Comparison data will be presented, showing good agreement between results from SPE methods and this new ‘direct injection’ method.
<blockquote>
Presenter: Stephen Somerville (Technical Director – PFAS, Bio-Sketch)
</blockquote>
<blockquote>
As the PFAS Technical Director, Mr. Somerville is responsible for the technical oversight of all the PFAS analysis operations within Pace’s nationwide network of environmental testing laboratories, including 8 PFAS centers of excellence. Mr. Somerville guides the development and implementation of both routine and customized analytical approaches throughout the network. Mr. Somerville is charged with leading efforts toward improving, standardizing, and expanding PFAS analytical services within each PFAS laboratory, as well as providing technical advice to sales, marketing, quality/compliance, project management and analytical teams within Pace.
</blockquote>

Agilent: Effective Use of Method EPA 8327/ASTM D8421/D8535 ‘Direct-Injection’ Techniques to Optimize Rapid TAT and Reduce Overall Project Costs

Effective Use of Method EPA 8327/ASTM D8421/D8535 ‘Direct-Injection’ Techniques to Optimize Rapid TAT and Reduce Overall Project Costs

‘Direct injection’ approach for PFAS analysis by LC-MS/MS, similar to the protocols described in EPA 8327 and ASTM D8421 & D8535.

Effective Use of Method EPA 8327/ASTM D8421/D8535

Who Should Attend:
Anyone new to SPE who wants to get familiar with the basics of SPE method development. Anyone who has a basic understanding of SPE and would like to learn how to improve their extractions. 
Key Learning Points:
<ul>
<li>Understand how to develop SPE methods from start to finish.</li>
<li>Receive general methods to use as starting points.</li>
<li>Learn when and how to optimize SPE methods, and discover new tips and tricks to make SPE method development easier.</li>
</ul>
<blockquote>
Presenter: Koen Askamp (Technical Specialist, Phenomenex)
</blockquote>
<blockquote>
Koen Askamp is a Technical Specialist at Phenomenex. He was awarded his BSc and MSc degrees in Molecular Life Sciences at Wageningen University in the Netherlands and joined Phenomenex in 2020 as Technical Sales Consultant. Koen became part of Phenomenex’s global technical support team in 2022 and assists laboratories in training chromatographers and developing analytical methods. 
</blockquote>

Phenomenex: Solid Phase Extraction Method Development

Solid Phase Extraction Method Development

Learn when and how to optimize SPE methods, and discover new tips and tricks to make SPE method development easier.

<h4>The Waters 2024 Virtual Summer School - An Educational Journey to Master Food &amp; Environmental Analysis</h4>Unlock the full potential of LC-MS techniques with our immersive and educational sessions at the Waters Virtual F&amp;E Late Summer School 2024. From September 24th to 26th, engage with leading experts and discover cutting-edge methods for environmental and food analysis.<h5>Why attend?</h5><ul><li>Comprehensive Learning: Dive deep into advanced LC-MS techniques and gain practical knowledge to enhance your laboratory's analytical capabilities.</li><li>Expert Insights: Learn from industry leaders and gain firsthand experience through detailed modules on chromatography, mass spectrometry, and sample preparation.</li><li>Regulatory Compliance: Stay ahead with the latest insights on EU regulations for PFAS analysis in food and water, ensuring your lab meets stringent standards.</li></ul><h3>Episode #5: General Sample Preparation | F&amp;E Summer School - Day 2 - Module 1</h3>Sample preparation is a key aspect in the analytical workflow and heavily determines the quality of the analysis. Solid Phase Extraction is a fundamental sample preparation technique widely used across all areas of analytical chemistry. Whether new to SPE or seeking a refresher, this webinar will introduce the basics of sample preparation and provide practical insights and technical background on the benefits when choosing SPE over another form of sample preparation, especially for analytes in complex matrices, such as the ones often encountered in Food and Environmental analysis. Join us in exploring SPE key parameters and best practices for implementing successful SPE methods. The session will combine PowerPoint slides with videos describing good practices and showing a practical example on the complex analysis of PFAS.Our guest speaker Chiara Sarti from Cranfield University, Bedford UK, will share her research results on the work with new dual layer cartridges to extract PFAS from different environmental samples.<h5>What you'll learn:</h5><ul><li>Understanding SPE fundamentals</li><li>Making SPE simple with water-wettable sorbents</li><li>Verifying successful SPE implementation</li></ul><blockquote>Presenter:&nbsp;Xavier Rodríguez (Business Development Manager Chemistry Group, Southern Europe, Waters)Xavier is part of the European Market Development Team. He works as an Application Specialist with focus on sample prep and has more than 20 years of experience in solving sample prep challenges.Presenter:&nbsp;Chiara Sarti (Ph.D. Student, Department of Chemistry "Ugo Schiff", University of Florence)</blockquote>

Waters Corporation: The Waters 2024 Virtual Summer School

General Sample Preparation

Join us in exploring SPE key parameters and best practices for implementing successful SPE methods. 

<h4>The Waters 2024 Virtual Summer School - An Educational Journey to Master Food &amp; Environmental Analysis</h4>Unlock the full potential of LC-MS techniques with our immersive and educational sessions at the Waters Virtual F&amp;E Late Summer School 2024. From September 24th to 26th, engage with leading experts and discover cutting-edge methods for environmental and food analysis.<h5>Why attend?</h5><ul><li>Comprehensive Learning: Dive deep into advanced LC-MS techniques and gain practical knowledge to enhance your laboratory's analytical capabilities.</li><li>Expert Insights: Learn from industry leaders and gain firsthand experience through detailed modules on chromatography, mass spectrometry, and sample preparation.</li><li>Regulatory Compliance: Stay ahead with the latest insights on EU regulations for PFAS analysis in food and water, ensuring your lab meets stringent standards.</li></ul><h3>Episode #6: Automated Sample Preparation | F&amp;E Summer School - Day 2 - Module 2</h3>This Module builds on the previous one by adding automation to the sample preparation methods. The Andrew+™ pipetting robot offers fully automated liquid handling using electronic pipettes and labware holders called Dominos for a full walk-away automation solution.Creating the connected laboratory, Andrew+ is part of the OneLab™ ecosystem, executing laboratory protocols designed in OneLab software. This flexible architecture enables you to effortlessly transition from laborious manual pipetting procedures to error-free, fully-robotized lab workflows – without any knowledge of programming, laboratory robotics or automation engineering. and explains processes the Andrew+ pipetting robot can take over in your lab.The European Union has adopted Commission Recommendation (EU) 2022/1431 to monitor PFAS in fruits, vegetables, milk and baby food. To achieve quantification at lowest levels of PFAS in food matrices, sample preparation is required which comprise of many pipetting steps and can be time-consuming and error prone. We will demonstrate an automate workflow for the analysis of PFAS in milk using a pipetting robot and stacked dual-phase SPE cartridges to meet EU 2022/1431 levels.<h5>What you'll learn:</h5>Possibilities to automat liquid handling processes in LC and LC-MS e.g.<ul><li>Serial dilution</li><li>Calibration curve</li><li>Solid Phase Extraction (SPE)</li></ul><blockquote>Presenter:&nbsp;Xavier Rodríguez (Business Development Manager Chemistry Group, Southern Europe, Waters)Xavier is part of the European Market Development Team. He works as an Application Specialist with focus on sample prep and has more than 20 years of experience in solving sample prep challenges.Presenter:&nbsp;Daniel Ng PhD (Principal Scientist, Waters Corporation)Daniel Ng received his PhD from the University of Manchester in mass spectrometry proteomics. He worked for 5 years at the Waters mass spectrometry headquarters in Wilmslow, UK, as a service support development engineer specializing in mass spectrometry instrumentation. In 2019, he took up a new role as a principal scientist at the International Food and Water Research Centre (Waters) in Singapore focusing on using advanced instrumentation to answer analytical challenges in the food and water industry. Since 2023, Daniel has lead the Food, Environmental and Material Science Analytical Professional Service team in the Asia-Pacific Region, developing analytical solutions to meet key challenges that customers face.</blockquote>

Automated Sample Preparation

The Andrew+™ pipetting robot offers fully automated liquid handling using electronic pipettes and labware holders.

Measurement of FT4 and FT3 is typically performed by immunoassay, however these can be prone to suffer from interferences and a lack of selectivity. Currently, the accepted gold standard for the measurement of FT4 and FT3 is using equilibrium dialysis (ED) and combined with the use of LC-MS/MS can overcome the issues with immunoassay in the measurement of FT4 and FT3. However, the equilibrium dialysis procedure can be quite time consuming and often being performed overnight.Here, we describe a simple clinical research method to perform ED using a commercially available device followed by sample preparation by solid phase extraction (SPE) and UPLC-MS/MS analysis using the Waters™ ACQUITY™ UPLC and analytically sensitive Xevo™ TQ Absolute Mass Spectrometer for clinical research. Data analysis and review has been simplified with the use of the waters_connect™ with QUAN Review Software. This has allowed for the complete workflow including equilibrium dialysis to be performed within a typical working day.Simplified Equilibrium Dialysis for the UPLC-MS/MS Analysis of Free Testosterone (FT) for Clinical ResearchHistorically, the measurement of free testosterone in human serum has presented a challenge for laboratory scientists, with such a large portion bound and the complexity and time involved in “gold standard” equilibrium dialysis. With a simple, fast, workflow combined with the analytical sensitivity afforded by the Waters Xevo™ TQ Absolute Mass Spectrometer, a newly developed, precise, accurate and selective clinical research method will be presented.<blockquote>Presenter: Robert Wardle (Senior Clinical Scientist, Waters Corporation)Robert Wardle is currently a Senior Scientist employed at Waters Corporation in Wilmslow, UK, performing research and development of applications and products for Clinical Research. His primary area of research is vitamins and in particular vitamin D metabolites, steroid hormones and in-depth knowledge of offline and online automation.Robert joined Waters in 2010 as a Clinical Validation Scientist, playing a key role in verification activities for the MassTrak XE Immunosuppressants kit available in the EU. He moved into his current role as a Senior Scientist in 2013, where he developed clinical research methods for a range of applications including vitamin D metabolites, estrogens, a large panel of steroid hormones and more recently this application on free T4 and free T3.Presenter: Stephen Balloch (Senior Clinical Scientist, Waters Corporation)Stephen Balloch graduated from the University of York (UK) with a Master’s degree in Chemistry, which included a strong focus on analytical chemistry. Subsequently he worked as a laboratory scientist in a GLP compliant research facility, progressing to Study Director. And, since 2010, he has been part of the clinical team at Waters (Wilmslow, UK). His principal focus has been on the development and validation of bioanalytical methods according to CLSI guidelines, with a focus on therapeutic drug monitoring. Additionally, he has supported newborn screening, vitamin and steroid analysis, including this clinical research method for free testosterone</blockquote>

Free Testosterone and Free T3/T4

Simplified Equilibrium Dialysis and SPE Method for the UPLC™-MS/MS Analysis of Free Thyroxine (FT4) and Triiodothyronine (FT3) for Clinical Research.

By attending this webinar, you will:<ul><li>Learn about method development steps undertaken to provide a robust and sensitive method for sample preparation of antibiotics in honey</li><li>Gain an understanding of the Biotage sample preparation workflow and the benefits of automation</li><li>Discover the challenges faced when developing a sample preparation method for antibiotics in honey</li></ul>Event OverviewThis presentation will detail different approaches to sample preparation for the analysis of antibiotics from honey prior to analysis on LC-MS/MS (Liquid Chromatography coupled to tandem Mass Spectrometry). It will compare different solid phase extraction (SPE) techniques to traditional QuEChERS and present Biotage's automatable cartridge SPE for QuEChERS clean-up.We will also discuss method development steps undertaken to fully optimize different sample preparation procedures for effective matrix removal and optimal recoveries for a panel of antibiotics from honey. The presentation will cover challenges faced during the development stages along with actions taken to overcome the issues as we develop an efficient sample preparation method. We will highlight the benefits of automating the methods within a laboratory to free up analysts' time and ensure good reproducibility.The presentation is aimed at laboratories that undertake food analysis and are interested in optimizing the clean-up of their food samples to produce accurate and reliable results. The focus will be on the best strategies used to fully remove matrix interferences while maintaining high recoveries and good reproducibility in honey testing.<blockquote>Presenter: Thomas Smith (EMEA Applications Laboratory Team Leader, Biotage)Thomas has been with Biotage since July 2022 and is supporting customers to streamline their sample preparation approaches and help them automate their manual, labour-intensive tasks in the laboratory. Prior to this, Thomas worked in a toxicology lab analyzing hair for drugs of abuse and alcohol markers. His main role was to automate a method to increase reproducibility and turnaround time to meet the growing sample numbers.</blockquote>

Separation Science: How to Prepare Honey Samples for Efficient Analysis of Antibiotics

How to Prepare Honey Samples for Efficient Analysis of Antibiotics

This presentation will detail different approaches to sample preparation for the analysis of antibiotics from honey prior to analysis on LC-MS/MS

LCMS webinars focusing on SPE | LabRulez LCMS