Regenerating liver uses ammonia to support de novo pyrimidine synthesis and cell proliferation
Scientific article | Science and research

Regenerating liver uses ammonia to support de novo pyrimidine synthesis and cell proliferation

Regenerating liver redirects ammonia metabolism to fuel de novo pyrimidine synthesis, enabling cell proliferation and tissue repair after hepatectomy through metabolic reprogramming.
Mo, 10.11.2025
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Regenerating liver uses ammonia to support de novo pyrimidine synthesis and cell proliferation
Synthesis and Evaluation of Pyridine-Based Antibacterial Agents that Inhibit ATP Synthase in Acinetobacter baumannii
Scientific article | Science and research

Synthesis and Evaluation of Pyridine-Based Antibacterial Agents that Inhibit ATP Synthase in Acinetobacter baumannii

A new class of trisubstituted pyridines targets ATP synthase in Acinetobacter baumannii. Four lead compounds showed potent antibacterial effects and synergized with colistin against multidrug-resistant strains.
Mo, 3.11.2025
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Synthesis and Evaluation of Pyridine-Based Antibacterial Agents that Inhibit ATP Synthase in Acinetobacter baumannii
Determination of Chemical Mixtures in Environmental, Food, and Human Samples Using High-Resolution Mass Spectrometry-Based Suspect Screening Approaches
Scientific article | Science and research

Determination of Chemical Mixtures in Environmental, Food, and Human Samples Using High-Resolution Mass Spectrometry-Based Suspect Screening Approaches

Suspect screening using LC- and GC-HRMS identified 547 chemicals across environmental, food, and human samples. Pharmaceuticals, pesticides, and personal care products were the most frequent contaminants.
Mo, 3.11.2025
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Determination of Chemical Mixtures in Environmental, Food, and Human Samples Using High-Resolution Mass Spectrometry-Based Suspect Screening Approaches
Hydrophilic Interaction Chromatography HRMS with Acrylamide Monolithic Columns: A Novel Approach for Intact Antibody Glycoform Characterization
Scientific article | Science and research

Hydrophilic Interaction Chromatography HRMS with Acrylamide Monolithic Columns: A Novel Approach for Intact Antibody Glycoform Characterization

This study introduces acrylamide monolith HILIC-MS for intact mAb glycoprofiling, offering high selectivity, baseline separation, and detection of low-abundance glycoforms missed by RPLC-MS.
Mo, 29.9.2025
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Hydrophilic Interaction Chromatography HRMS with Acrylamide Monolithic Columns: A Novel Approach for Intact Antibody Glycoform Characterization
Ion-Pairing Hydrophilic Interaction Chromatography for Impurity Profiling of Therapeutic Phosphorothioated Oligonucleotides
Scientific article | Science and research

Ion-Pairing Hydrophilic Interaction Chromatography for Impurity Profiling of Therapeutic Phosphorothioated Oligonucleotides

Ion-pairing HILIC improves impurity profiling of therapeutic oligonucleotides. It resolves deaminated impurities from full-length products, beyond current LC-MS limits.
Mo, 22.9.2025
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Ion-Pairing Hydrophilic Interaction Chromatography for Impurity Profiling of Therapeutic Phosphorothioated Oligonucleotides
Global Careers in Liquid Chromatography: 20+ LC Jobs in Service, Sales & Research
Article | Career

Global Careers in Liquid Chromatography: 20+ LC Jobs in Service, Sales & Research

Browse over 20 job offers in liquid chromatography from Waters, Agilent, Thermo, Shimadzu, Metrohm and others. Roles in sales, applications, service, and R&D.
Fr, 12.9.2025
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Global Careers in Liquid Chromatography: 20+ LC Jobs in Service, Sales & Research
Global LCMS Conferences and Training 2025 – LabRulez
Article | Events

Global LCMS Conferences and Training 2025 – LabRulez

Explore global LCMS events in 2025: conferences, courses, workshops, and training. Stay updated on cutting-edge LC/MS methods and connect with experts worldwide.
Fr, 5.9.2025
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Global LCMS Conferences and Training 2025 – LabRulez
Global Careers in LC-MS: Explore Analytical Chemistry Jobs Around the World
Article | Career

Global Careers in LC-MS: Explore Analytical Chemistry Jobs Around the World

Discover 39+ global job opportunities in LC-MS. Roles span R&D, applications, sales, and service across Europe, North America, Asia, and Australia.
Th, 7.8.2025
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Global Careers in LC-MS: Explore Analytical Chemistry Jobs Around the World
Quantitative Assessment of a Novel Device Designed for Patient-centric Sampling of Dried Plasma Using Targeted Proteomics
Scientific article | Science and research

Quantitative Assessment of a Novel Device Designed for Patient-centric Sampling of Dried Plasma Using Targeted Proteomics

A new dried plasma microsampling device enables home sampling with high precision and stability, correlating strongly (R > 0.99) with conventional plasma in targeted proteomic analysis.
Mo, 4.8.2025
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Quantitative Assessment of a Novel Device Designed for Patient-centric Sampling of Dried Plasma Using Targeted Proteomics
Comprehensive IC-ICP-MS analysis of polyphosphonates and their transformation products
Scientific article | Science and research

Comprehensive IC-ICP-MS analysis of polyphosphonates and their transformation products

This study aims to develop and validate a rapid IC-ICP-MS method for identifying and quantifying polyphosphonates and their transformation products under environmental conditions.
Mo, 7.7.2025
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Comprehensive IC-ICP-MS analysis of polyphosphonates and their transformation products
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