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Reduce Sample Waste in the Lab Using Real-Time Data Evaluation with Automated Reactions
Article | Software

Reduce Sample Waste in the Lab Using Real-Time Data Evaluation with Automated Reactions

Reduce sample waste and prevent data loss in LC-MS analysis using real-time data evaluation with system suitability testing and intelligent run control in Chromeleon software.
Tu, 27.1.2026
Thermo Fisher Scientific
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Reduce Sample Waste in the Lab Using Real-Time Data Evaluation with Automated Reactions
Hydrophilic Interaction Chromatography HRMS with Acrylamide Monolithic Columns: A Novel Approach for Intact Antibody Glycoform Characterization
Scientific article | Science and research

Hydrophilic Interaction Chromatography HRMS with Acrylamide Monolithic Columns: A Novel Approach for Intact Antibody Glycoform Characterization

This study introduces acrylamide monolith HILIC-MS for intact mAb glycoprofiling, offering high selectivity, baseline separation, and detection of low-abundance glycoforms missed by RPLC-MS.
Mo, 29.9.2025
LabRulez
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Hydrophilic Interaction Chromatography HRMS with Acrylamide Monolithic Columns: A Novel Approach for Intact Antibody Glycoform Characterization
Collision-Based Ion-activation and Dissociation
Article | Academy

Collision-Based Ion-activation and Dissociation

Collision-based ion activation, developed nearly 80 years ago, remains the most widely used fragmentation method. Learn about three key techniques on Thermo Scientific MS.
Tu, 23.9.2025
Thermo Fisher Scientific
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Collision-Based Ion-activation and Dissociation
Ion-Pairing Hydrophilic Interaction Chromatography for Impurity Profiling of Therapeutic Phosphorothioated Oligonucleotides
Scientific article | Science and research

Ion-Pairing Hydrophilic Interaction Chromatography for Impurity Profiling of Therapeutic Phosphorothioated Oligonucleotides

Ion-pairing HILIC improves impurity profiling of therapeutic oligonucleotides. It resolves deaminated impurities from full-length products, beyond current LC-MS limits.
Mo, 22.9.2025
LabRulez
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Ion-Pairing Hydrophilic Interaction Chromatography for Impurity Profiling of Therapeutic Phosphorothioated Oligonucleotides
Development and thorough evaluation of a multi-omics sample preparation workflow for comprehensive LC-MS/MS-based metabolomics, lipidomics and proteomics datasets
Scientific article | Science and research

Development and thorough evaluation of a multi-omics sample preparation workflow for comprehensive LC-MS/MS-based metabolomics, lipidomics and proteomics datasets

This study aimed to develop and compare ten extraction protocols to find the most effective method for generating metabolomics, lipidomics, and proteomics data from postmortem tissue.
Mo, 30.6.2025
LabRulez
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Development and thorough evaluation of a multi-omics sample preparation workflow for comprehensive LC-MS/MS-based metabolomics, lipidomics and proteomics datasets
Mucinomics: The Next Frontier of Mass Spectrometry
Article | Science and research

Mucinomics: The Next Frontier of Mass Spectrometry

Dr. Stacy Malaker shared advances in mucin characterization, enrichment, and their role in disease research during a Nature webinar. Here are the key takeaways.
Tu, 24.6.2025
Thermo Fisher Scientific
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Mucinomics: The Next Frontier of Mass Spectrometry
Metabolomics of Withania somnifera L. extracts by an integrated LC-MS and NMR approach and evaluation of their tyrosinase inhibitory activity
Scientific article | Science and research

Metabolomics of Withania somnifera L. extracts by an integrated LC-MS and NMR approach and evaluation of their tyrosinase inhibitory activity

This study analyzed Withania somnifera extracts from various eco-friendly methods using LC-MS/NMR, and evaluated their metabolite profiles and tyrosinase inhibitory activity.
Mo, 2.6.2025
LabRulez
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Metabolomics of Withania somnifera L. extracts by an integrated LC-MS and NMR approach and evaluation of their tyrosinase inhibitory activity
Live from the Lab: Solutions for Omics Research - Dr Thomas Moehring & Dr Hamish Stewart
Article | Events

Live from the Lab: Solutions for Omics Research - Dr Thomas Moehring & Dr Hamish Stewart

Join us on June 12th for the 3rd edition of Live from the Lab! This hybrid event will showcase the latest advancements in mass spectrometry technology.
Tu, 20.5.2025
Thermo Fisher Scientific
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Live from the Lab: Solutions for Omics Research - Dr Thomas Moehring & Dr Hamish Stewart
Imaging Large Multiprotein Complexes Using Native Nano DESI Mass Spectrometry
Article | Science and research

Imaging Large Multiprotein Complexes Using Native Nano DESI Mass Spectrometry

Prof. Helen Cooper from the University of Birmingham shared new insights into imaging large multiprotein complexes using native nano-DESI mass spectrometry.
Tu, 29.4.2025
Thermo Fisher Scientific
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Imaging Large Multiprotein Complexes Using Native Nano DESI Mass Spectrometry
Quantification of Gd species in a tetrameric Gd-based contrast agent using HPLC-ICP-MS
Scientific article | Science and research

Quantification of Gd species in a tetrameric Gd-based contrast agent using HPLC-ICP-MS

This study presents an HPLC-ICP-MS method for precise quantification of Gd complexes in Gadoquatrane, enabling detection of trace by-products to optimize synthesis and drug control strategies.
Mo, 17.3.2025
LabRulez
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Quantification of Gd species in a tetrameric Gd-based contrast agent using HPLC-ICP-MS
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LabRulez s.r.o. All rights reserved. Content available under a CC BY-SA 4.0 Attribution-ShareAlike