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Analysis of polysorbates in biotherapeutic products using two-dimensional HPLC coupled with mass spectrometer

 

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PO-CON1513E Analysis of Polysorbate 80 in Protein Formulations Using 2D LCMS Pittcon 2015 2530-11P William Hedgepeth1, Kenichiro Tanaka1, Keiko Yamabe2 1 Shimadzu Scientific Instruments, Inc., Columbia MD; Shimadzu Corporation, Kyoto Japan 2 Analysis of Polysorbate 80 in Protein Formulations Using…
Key words
polyoxyethylene, polyoxyethylenemobile, mobilephase, phasepolysorbates, polysorbatesflow, flowsorbitan, sorbitansample, samplepolysorbate, polysorbatecolumn, columnvalve, valvepretreatment, pretreatmentdetection, detectioninjection, injectionmodel, modelbiotherapeutic
LAAN-A-LC-E264 Application News L487 High Performance Liquid Chromatography Analysis of Polysorbate 80 in IgG Aqueous Solution by Online SPE Using a Shim-pack MAYI Column – Part 2 No. Polysorbates play a role in maintaining the stability of proteins to prevent…
Key words
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LAAN-A-LC-E263 Application News L486 High Performance Liquid Chromatography Analysis of Polysorbate 80 in IgG Aqueous Solution by Online SPE Using Shim-pack MAYI Column – Part 1 No. Various analyses are required in the evaluation of drugs. When analyzing samples that…
Key words
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Simultaneous analysis of polysorbate 80 and poloxamer 188 in biopharmaceutical formulations using charged aerosol detector and single quadrupole mass spectrometer Xuepu Li 1, Sissi White 2, Mauro De Pra 3, Yu Cui 1, Min Du 2 1Thermo Fisher Scientific, Shanghai,…
Key words
poloxamer, poloxamerpoe, poeoleate, oleatesorbitan, sorbitanromiplostim, romiplostimisosorbide, isosorbideprotein, proteinconcentration, concentrationcad, cadsurfactants, surfactantsisq, isqformulations, formulationspolysorbates, polysorbatespolysorbate, polysorbatersd
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