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C10G-E054Solutions forBiopharmaceuticalApplication NotebookFirst Edition: December, 2017© Shimadzu Corporation, 2017 Solutions forBiopharmaceuticalIndexApplication NotebookBioanalysisLCMS Bioanalysis of Antibody Drugs Using Fab-Selective Proteolysis nSMOL - Trastuzumab analysis nSMOL, which enables selective proteolysis of the Fab region of monoclonal antibodies, was applied to Trastuzumab bioanalysis.LCMS Bioanalysis...
Key words
acid, acidamino, aminoantibody, antibodyglycan, glycannsmol, nsmolerexim, ereximstructure, structurenews, newsaggregates, aggregatesnucleic, nucleicglycans, glycansanalysis, analysisaggregate, aggregatesizer, sizerprotein
LAAN-A-LC-E263ApplicationNewsL486High Performance Liquid ChromatographyAnalysis of Polysorbate 80 in IgG Aqueous Solutionby Online SPE Using Shim-pack MAYI Column – Part 1No.Various analyses are required in the evaluation of drugs.When analyzing samples that contain macromolecularproteins at high concentrations by reversed phaseHPLC, degradation...
Key words
mobile, mobilephase, phasemayi, mayicolumn, columnpretreatment, pretreatmentshim, shimflowrate, flowratepack, packchemically, chemicallyuvdetector, uvdetectormonooleate, monooleateinfiltrate, infiltratepolyoxyethylene, polyoxyethylenesorbitan, sorbitanmodified
LAAN-A-LC-E264ApplicationNewsL487High Performance Liquid ChromatographyAnalysis of Polysorbate 80 in IgG Aqueous Solution byOnline SPE Using a Shim-pack MAYI Column – Part 2No.Polysorbates play a role in maintaining the stability ofproteins to prevent their denaturation, so they are oftenadded to protein formulations....
Key words
polyoxyethylene, polyoxyethylenesorbitan, sorbitanmobile, mobilepolysorbate, polysorbatephase, phasenews, newsflowrate, flowratewoh, wohuvdetector, uvdetectorpolysorbates, polysorbatesfatty, fattydeproteinization, deproteinizationcolumn, columnmass, massgradual
PO-CON1450EAnalysis of polysorbates in biotherapeuticproducts using two-dimensionalHPLC coupled with mass spectrometerASMS 2014WP 182William Hedgepeth, Kenichiro TanakaShimadzu Scientific Instruments, Inc., Columbia MD Analysis of polysorbates in biotherapeutic productsusing two-dimensional HPLC coupled with mass spectrometerIntroductionPolysorbate 80 is commonly used for biotherapeuticproducts to prevent...
Key words
polysorbates, polysorbatespolyoxyethylene, polyoxyethylenebiotherapeutic, biotherapeuticmobile, mobiledimensional, dimensionalspectrometer, spectrometerphase, phasecoupled, coupledhplc, hplcmass, massflow, flowtwo, twoisosorbide, isosorbideproducts, productssorbitan
 

Similar PDF

C10G-E054Solutions forBiopharmaceuticalApplication NotebookFirst Edition: December, 2017© Shimadzu Corporation, 2017 Solutions forBiopharmaceuticalIndexApplication NotebookBioanalysisLCMS Bioanalysis of Antibody Drugs Using Fab-Selective Proteolysis nSMOL - Trastuzumab analysis nSMOL, which enables selective proteolysis of the Fab region of monoclonal antibodies, was applied to Trastuzumab bioanalysis.LCMS Bioanalysis...
Key words
acid, acidamino, aminoantibody, antibodyglycan, glycannsmol, nsmolerexim, ereximstructure, structurenews, newsaggregates, aggregatesnucleic, nucleicglycans, glycansanalysis, analysisaggregate, aggregatesizer, sizerprotein
LAAN-A-LC-E263ApplicationNewsL486High Performance Liquid ChromatographyAnalysis of Polysorbate 80 in IgG Aqueous Solutionby Online SPE Using Shim-pack MAYI Column – Part 1No.Various analyses are required in the evaluation of drugs.When analyzing samples that contain macromolecularproteins at high concentrations by reversed phaseHPLC, degradation...
Key words
mobile, mobilephase, phasemayi, mayicolumn, columnpretreatment, pretreatmentshim, shimflowrate, flowratepack, packchemically, chemicallyuvdetector, uvdetectormonooleate, monooleateinfiltrate, infiltratepolyoxyethylene, polyoxyethylenesorbitan, sorbitanmodified
LAAN-A-LC-E264ApplicationNewsL487High Performance Liquid ChromatographyAnalysis of Polysorbate 80 in IgG Aqueous Solution byOnline SPE Using a Shim-pack MAYI Column – Part 2No.Polysorbates play a role in maintaining the stability ofproteins to prevent their denaturation, so they are oftenadded to protein formulations....
Key words
polyoxyethylene, polyoxyethylenesorbitan, sorbitanmobile, mobilepolysorbate, polysorbatephase, phasenews, newsflowrate, flowratewoh, wohuvdetector, uvdetectorpolysorbates, polysorbatesfatty, fattydeproteinization, deproteinizationcolumn, columnmass, massgradual
PO-CON1450EAnalysis of polysorbates in biotherapeuticproducts using two-dimensionalHPLC coupled with mass spectrometerASMS 2014WP 182William Hedgepeth, Kenichiro TanakaShimadzu Scientific Instruments, Inc., Columbia MD Analysis of polysorbates in biotherapeutic productsusing two-dimensional HPLC coupled with mass spectrometerIntroductionPolysorbate 80 is commonly used for biotherapeuticproducts to prevent...
Key words
polysorbates, polysorbatespolyoxyethylene, polyoxyethylenebiotherapeutic, biotherapeuticmobile, mobiledimensional, dimensionalspectrometer, spectrometerphase, phasecoupled, coupledhplc, hplcmass, massflow, flowtwo, twoisosorbide, isosorbideproducts, productssorbitan
 

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