Analysis of Antibody-Drug Conjugates Using Size Exclusion Chromatography and Mass Spectrometry

Applications | 2017 | Agilent TechnologiesInstrumentation
LC/TOF, LC/HRMS, LC/MS, LC/MS/MS, GPC/SEC
Industries
Pharma & Biopharma
Manufacturer
Agilent Technologies
Key words
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Size Exclusion Chromatography/ Mass Spectrometry Analysis of Antibody Drug Conjugates Using the Agilent 1260 Infinity II Bio-Inert LC Application Note Biologics & Biosimilars Author Abstract Sonja Schneider Recombinant monoclonal antibodies (mAbs) have emerged as important Agilent Technologies, Inc. therapeutic agents…
Key words
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Key words
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Application Note Biologics SEC Coupled to High-Resolution Mass Spectrometry for Detailed Characterization of mAbs and ADCs Authors Isabel Vandenheede, Lucie Jorge, Pat Sandra, and Koen Sandra Research Institute for Chromatography (RIC) President Kennedypark 26 B-8500 Kortrijk Linda Lloyd, Anne Blackwell,…
Key words
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Application Note Pharma & Biopharma Sensitive Native Mass Spectrometry of Macromolecules Using Standard Flow LC/MS Author David L. Wong Agilent Technologies, Inc. Abstract Native mass spectrometry can be used for a variety of protein-based applications, such as protein-protein interaction, protein-ligand…
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native, nativeprotein, proteincounts, countsintact, intactdeconvoluted, deconvolutedamu, amumyoglobin, myoglobinmass, massapomyoglobin, apomyoglobincharge, chargeheme, hemecomplexes, complexesholomyoglobin, holomyoglobintetramer, tetramerdenatured
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