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Fragment-Based Drug Discovery: Comparing Labeled and Label-Free Screening of β-Amyloid Secretase (BACE-1) Using Fluorescence Spectroscopy and Ultrafast SPE/MS/MS

Applications | 2013 | Agilent TechnologiesInstrumentation
Sample Preparation, HPLC, LC/MS, LC/MS/MS, LC/QQQ
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Clinical Research
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Agilent Technologies
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RapidFire for Automated High-Throughput LC/MS
2023|Agilent Technologies|Guides
RapidFire for Automated High-Throughput LC/MS Proven. Rapid. Complete. Application Compendium Table of Contents Introduction3 Application Notes Method Development High-Throughput (Sub-2.5 Second) Direct Injection Analysis by  Mass Spectrometry 4 Automated Method Development Using the Agilent RapidFire  High-Throughput Mass Spectrometry…
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Ultrafast Histone Deacetylase Selectivity Screening Using the Agilent RapidFire High-Throughput Mass Spectrometry System Application Note Authors Abstract Lauren E. Frick and William A. LaMarr Selectivity screening of a promising new compound requires testing against a Agilent Technologies, Inc. host of…
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High-Throughput Analysis of Epigenetic Targets with Agilent RapidFire/MS Systems: Sirtuin (SIRT) Enzymes Application Note Author Introduction Peter Rye, Lauren Frick, and William LaMarr Agilent Technologies, Inc. Wakefield, MA USA Histones and other proteins are subject to a variety of posttranslational…
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High-Throughput Lead Discovery with Agilent RapidFire/MS Systems: Analysis of UDP-3-O-(R-3-hydroxymyristoyl)-NAcetylglucosamine Deacetylase (LpxC) Application Note Authors Introduction William Lamarr, Lauren Frick, and Peter Rye Agilent Technologies, Inc. Wakefield, MA USA The RapidFire High-throughput Mass Spectrometry System provides drug discovery researchers with…
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