LCMS
More information
WebinarsAbout usContact usTerms of use
LabRulez s.r.o. All rights reserved. Content available under a CC BY-SA 4.0 Attribution-ShareAlike

High-throughput, Ion-Pairing-Free, HILIC Analysis of Oligonucleotides Using Agilent RapidFire Coupled to Quadrupole Time-of-Flight Mass Spectrometry

Applications | 2022 | Agilent TechnologiesInstrumentation
Sample Preparation, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS
Industries
Pharma & Biopharma
Manufacturer
Agilent Technologies
Key words
Downloadable PDF for viewing
 

Similar PDF

Toggle
RapidFire for Automated High-Throughput LC/MS
2023|Agilent Technologies|Guides
RapidFire for Automated High-Throughput LC/MS Proven. Rapid. Complete. Application Compendium Table of Contents Introduction3 Application Notes Method Development High-Throughput (Sub-2.5 Second) Direct Injection Analysis by  Mass Spectrometry 4 Automated Method Development Using the Agilent RapidFire  High-Throughput Mass Spectrometry…
Key words
rapidfire, rapidfirecounts, countsthroughput, throughputsip, sipwere, wereoligo, oligomass, masstof, tofagilent, agilentcartridge, cartridgehigh, highmethod, methoddata, dataoligos, oligosfrom
Application Note BioPharma MS1 Oligonucleotide Characterization Using LC/Q-TOF with HILIC Chromatography Authors Introduction Peter Rye and Cody Schwarzer Agilent Technologies, Inc. The synthesis of RNA and DNA oligonucleotides (oligos) is an iterative process that, despite highly optimized chemistry, results in…
Key words
counts, countsdeconvoluted, deconvolutedsirna, sirnaoligos, oligosamu, amumass, masscharge, chargeoligo, oligohilic, hilicribose, riboseimpurities, impuritiesduplex, duplexwide, widedepur, depurtime
Application Note BioPharma MS/MS Oligonucleotide Sequencing Using LC/Q-TOF with HILIC Chromatography Authors Guannan Li and Peter Rye Agilent Technologies, Inc. Introduction Oligonucleotides are commonly analyzed by liquid chromatography/mass spectrometry (LC/MS) in negative ion polarity mode using ion-pairing reversed‑phase (IP‑RP) methods.…
Key words
charge, chargecounts, countsribose, riboseoligonucleotides, oligonucleotidesmass, masscollision, collisionhilic, hilicacquisition, acquisitionfragments, fragmentsoligo, oligosequence, sequencemultiple, multiplespectrum, spectrumoligonucleotide, oligonucleotideaptamer
Application Note Pharma & Biopharma Oligonucleotides Oligonucleotide Characterization by Agilent 1290 Infinity II Bio LC and 6545XT AdvanceBio LC/Q-TOF Oligonucleotide identity, impurities analysis and sequence determination using BioConfirm 12.0 target plus impurities (TPI) and sequence confirmation workflows Authors Introduction Bian…
Key words
oligonucleotide, oligonucleotideaso, asosequence, sequencetpi, tpicounts, countsacquisition, acquisitionconfirmation, confirmationoligonucleotides, oligonucleotidesworkflow, workflowcharge, chargeimpurities, impuritiesbioconfirm, bioconfirmmass, massagilent, agilentfluoro
Other projects
Follow us
More information
WebinarsAbout usContact usTerms of use
LabRulez s.r.o. All rights reserved. Content available under a CC BY-SA 4.0 Attribution-ShareAlike