An automated high-throughput workflow for peptide mapping to monitor post-translational modifications (PTMs) of monoclonal antibodies
Applications | 2018 | Thermo Fisher ScientificInstrumentation
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
IndustriesClinical Research
ManufacturerThermo Fisher Scientific
Key wordschain, heavy, eeqynstyr, tkpreeqynstyr, mnslqsndtaiyycar, light, cetuximab, kingfisher, wqqgnvfscsvmhealhnhytqk, smart, digest, duo, magnetic, prime, srwqqgnvfscsvmhealhnhytqk, vqwkvdnalqsgnsqesvteqdsk, modification, adalimumab, nqvsltclvk, peptide, relative, sequence, bevacizumab, diqmtqspsslsasvgdr, hkvyacevthqglsspvtk, abundance, intesity, mapping, protein, kit, fnwyvdgvevhnaktkpr, mabs, gpsvfplapsskstsggtaalgclvk, vsnkalpapiek, gfypsdiavewesngqpennyk, rituximab, ptms, slslspgk, deamidation, vdnalqsgnsqesvteqdsk, vyacevthqglsspvtk, sgtasvvcllnnfypr, fnwyvdgvevhnak, trastuzumab, vqwk, adyekhk, ckvsnk, nslylqmnslr, vvsvltvlhqdwlngk, antibodies
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SMART Digest Peptide Mapping and Quantitation Compendium
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Table of Contents Introduction Faster and More Sensitive Protein Characterization and Quantitation Easier Digestion Faster Digestion Highly Reproducible Digestion Automation of Digestion Improving Sensitivity and Speed SMART Digest Peptide Mapping and Quantitation Compendium Peptide Mapping Peptide Quantitation Product and Method…
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Comparison of alternative approaches to trypsin protein digestion for reproducible and efficient peptide mapping analysis of monoclonal antibodies
2018|Thermo Fisher Scientific|Applications
APPLICATION NOTE 21782 Comparison of alternative approaches to trypsin protein digestion for reproducible and efficient peptide mapping analysis of monoclonal antibodies Authors Silvia Millán-Martín, Craig Jakes, Noemi Dorival-García, Nicola McGillicuddy, Sara Carillo, Amy Farrell, Jonathan Bones National Institute for Bioprocessing…
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smart, smartdigest, digestadalimumab, adalimumabdigestion, digestionmagnetic, magneticmodifications, modificationsalternative, alternativepeptide, peptiderapid, rapidmapping, mappingdeamidation, deamidationrelative, relativenistmab, nistmabinduced, inducedsample
Investigating process-related post-translational modifications in NISTmAb RM 8671 using high-throughput peptide mapping analysis
2018|Thermo Fisher Scientific|Applications
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eeqynstyr, eeqynstyrtkpreeqynstyr, tkpreeqynstyrpeptide, peptidesmart, smartdigestion, digestionsequence, sequencemodifications, modificationsrelative, relativemapping, mappingscientific, scientificterminal, terminaldigest, digestptms, ptmsoptima, optimaabundance
High-throughput peptide mapping of trastuzumab using a tandem LC-MS workflow
2020|Thermo Fisher Scientific|Applications
APPLICATION NOTE 73784 High-throughput peptide mapping of trastuzumab using a tandem LC-MS workflow Authors: Sara Carillo ([email protected]), Silvia Millán Martín, and Jonathan Bones NIBRT – The National Institute for Bioprocessing Research and Training, Dublin, Ireland Keywords: Monoclonal antibody, mass spectrometry,…
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