The Go-To Core-Shell Selectivity for Hydrophobic Compounds!
The well-rounded, all-purpose core-shell Kinetex C18 HPLC column produces high efficiencies compared to traditional, fully porous columns. HPLC C18 columns come in various configurations to ensure outstanding performance and are recognized as the most retentive among alkyl-bonded phases. When used with UHPLC systems, the 2.6 µm size achieves similar performance to fully porous sub-2 µm particles but at significantly lower backpressure. Yielding remarkable chromatographic resolution, higher peak capacities, and greater sensitivity, the Kinetex C18 columns maximize the efficiency of every HPLC or UHPLC analysis.
Advantages of Kinetex Core-Shell C18 HPLC Columns
Phenomenex: Kinetex-C18
The Kinetex C18 column is fully compatible with all UHPLC instruments, ensuring seamless integration into any lab setup. This column is designed for easy installation and optimal performance. For installation, loosen the collet, place the tool between the gold compression screw and collet for quick release, adjust the tubing to the correct port depth, and connect the Kinetex column to the end-fitting. This universal compatibility allows you to leverage the powerful sub-2 µm column technology across different systems effortlessly.
The Kinetex C18 column offers a well-balanced C18 phase that delivers the highest level of hydrophobic selectivity compared to other Kinetex phases.
Enhance your analytical method instantly by upgrading to the Kinetex C18 column for superior performance. Take advantage of the fully scalable available particle sizes of Kinetex C18 to bring improved performance to any LC system!
Phenomenex: Fully porous vs Core-shell C18 ColumnsQuickly improve the productivity and performance of your existing methods and utilize the core-shell advantage to deliver the performance you need at backpressures the system can handle.
Stationary phase Kinetex Core-Shell C18 is provided in these column types: analytical and preparative
Kinetex Core-Shell Technology delivers dramatic improvements in efficiency over conventional fully porous media, which can be leveraged to increase resolution, significantly improve productivity, reduce solvent consumption, and decrease costs. Whether you are running high-performance liquid chromatography (HPLC) or ultra-high performance liquid chromatography (UHPLC) methods, the Kinetex core-shell family can deliver shockingly improved performance over the current column you are using. Phenomenex designs, manufactures, and sells its very own silica and organo-silica core-shell particles.
Advantages of Kinetex HPLC Columns
Core-shell technology in chromatography is a revolutionary approach that enhances the efficiency of HPLC systems while minimizing costs. Core-shell particles are designed with a solid, non-porous silica core surrounded by a porous outer layer. This unique structure allows for faster analyte mass transfer between the mobile and stationary phases, as diffusion occurs only through the thin, porous shell rather than the entire particle. This minimizes band broadening, leading to higher separation efficiency and sharper peaks.
The consistency in size and shape of core-shell particles further enhances separation efficiency by reducing variability in analyte movement. As a result, core-shell HPLC columns provide high efficiency and resolution at lower backpressures, making them an ideal choice for labs looking to improve their existing HPLC systems without the need for costly UHPLC equipment.
Core-shell technology thus offers a cost-effective alternative to upgrading to UHPLC systems, enabling labs to maximize the efficiency of their current HPLC setups. The formation of these particles through advanced sol-gel processing techniques ensures uniformity and reliability, making them a valuable tool in modern chromatography. By using the Kinetex HPLC column, laboratories can achieve faster analysis times and higher productivity while maintaining excellent separation performance.
The 5 versatile particle sizes allow you to select the best fit for your instrument.
Phenomenex: Five versatile particle sizes of Kinetex Core-Shell Technology Columns
Using sol-gel processing techniques that incorporate nano-structuring technology, a durable, homogeneous porous shell is grown on a solid silica core to create a Kinetex Core-Shell particle. This particle morphology results in less band broadening for all four sources of UHPLC band broadening compared to fully porous particles and thus delivers extremely high efficiencies.
Kinetex particles are characterized by an exceptionally consistent size distribution, with particles being nearly monodispersed, meaning they are uniform in size. This precise uniformity plays a crucial role in minimizing variability within the column, leading to enhanced separation efficiency and sharper peaks.
The nearly monodispersed nature of these particles ensures that the flow of the mobile phase remains consistent, reducing the likelihood of irregularities that can impact results. As a result, Kinetex columns deliver highly reliable and reproducible performance, making them ideal for achieving consistent analytical outcomes acrLC Kinetex Core-Shell Technolooss various applications.
Phenomenex: Kinetex Polar C18 vs Fully Porous phase
The combination of a consistent, solid, high-density core along with proprietary column packing technologies in the Kinetex HPLC column ensures optimum bed structure and high column performance. This carefully designed core structure promotes uniform packing of the particles, which is essential for minimizing band-broadening effects that can arise from Eddy Diffusion.
The manufacturing process of Kinetex columns is tightly controlled, focusing on factors such as particle size distribution, surface and bonding homogeneity, and packing quality. This meticulous engineering leads to uniform packing and minimized band-broadening, resulting in superior separation efficiency.
Phenomenex: Core-shell vs Fully Porous.jpg
Kinetex core-shell particle LC columns deliver exceptional performance enhancements across any LC system, offering unmatched efficiency and resolution. With a choice of 11 diverse stationary phases, these columns cater to a wide range of chromatographic applications, ensuring optimal separation for various analytes.
Additionally, the availability of five versatile particle sizes allows for precise method tailoring, enabling both high-speed and high-resolution separations. Whether you're using HPLC or UHPLC systems, Kinetex columns provide the flexibility and performance needed to achieve superior analytical results.
