
Improve Peak Shape for Bases Without the Headache
Luna Omega PS C18 is a unique mixed interaction stationary phase that provides incredibly useful polar and non-polar retention. The surface of the PS C18 contains a positive charge which aids in the retention of acidic compounds and provides better peak shape for bases through ionic interactions, while the C18 ligand promotes general reversed phase retention. This mixed-mode selectivity allows for greater separation between compounds with varying functional groups.
Phenomenex: Luna Omega PS C18 HPLC Column
Luna Omega PS C18 has been fine tuned and manufactured by Phenomenex to provide a mixed selectivity that is highly useful for method development involving either combinations of polar and nonpolar compounds, or just one single compound class with small changes in functional groups.
With its positive surface (PS) the Luna Omega PS C18 provides valuable increase in retention of acids through ionic/polar interactions. In addition, the C18 ligand also stimulates hydrophobic retention that greatly promotes increased resolution between analytes of interest.
Traditional C18 phases may not always be the best option. A HPLC and UHPLC column that has both polar and hydrophobic versatility allows for great method development flexibility.
While traditional alkyl phases are prone to show tailing for basic compounds because of secondary interactions occurring at the silica surface, the surface of the Luna Omega PS C18 was designed with positive charges that serve to repel strong basic species and consistently display sharp peak shape.
Phenomenex: Better Peak Shape for Bases (Comparison of Luna Omega PS C18 with C18 Columns from other manufacturers)
Stationary phase Luna Omega PS C18 is provided in these column types: analytical, minibore, midbore and preparative
Minibore Columns
MidBore Columns
Analytical Columns
The cutting edge thermally modified Luna Omega particle delivers high efficiency, ruggedness, reproducibility, and dependability for a wide range of chromatographic analyses. Luna Omega HPLC and UHPLC columns are built upon more then 20 years of applied knowledge, invention, and customer experience in the manufacture and packing of LC columns. The particle’s novel design and proprietary manufacturing process results in greater particle inertness, a stronger particle morphology, and more consistent porosity.
Phenomenex:Thermal modified pore structure of Luna Omega Column particles
The undeniably high efficiency levels found in each Luna Omega UHPLC column provide you with the potential of huge gains in method performance. While traditional silica and hybrid fully porous particles claim high performance, when compared to Luna Omega 1.6 μm, they drastically fall short and prevent UHPLC scientists from reaching their UHPLC potential.
Our industry leading bonding technologies in conjunction with high efficiency levels ensure excellent stationary phase coverage and improved separation power. Now, with Luna Omega 1.6 μm, you can turn difficult separations into resolution achievements.
Luna Omega UHPLC columns contain a unique silica modified using a proprietary, post-synthetic thermal treatment process to provide extraordinary mechanical strength and significantly greater inertness than traditional fully porous and hybrid materials. This greatly minimizes secondary interactions that negatively affect peak shape, allowing for greater method accuracy.
Batch-to-batch and column-to-column, Luna® Omega media and columns are designed to be consistent and incredibly accurate tools for your analysis. Each batch and column are quality tested to ensure dependability and reproducibility.

