KNAUER Eurospher II Chiral NR Prep Columns for NP & RP

Eurospher II Chiral NR is an immobilized brush-type phase with very broad generality and orhogonal selectivity to Eurospher II Chiral AM and OM. In many cases it is much more stable compared to Eurospher II Chiral AM or OM. The Chiral-NR selector is covalently bound, so that you can use all HPLC-eluents.

Due to its high loadability it is perfectly suited for preparative separations. Both phases can be used in RP and NP mode. Eurospher II Chiral-NR-R shows reversed elution order compared to Eurospher II Chiral-NR caused by the modification with the opposite enantiomeric form of the chiral selector.

Properties

• Silica gel: ultra pure, > 99.99 %
• Metal content: < 10 ppm
• Particle size: 
  • Eurospher II Chiral NR: 3 μm, 5 μm, 8 µm, 12 µm
  • Eurospher II Chiral NR-R: 8 µm, 12 µm
• Particle form: spherical
• Pore size of base material: 1000 Å

Recommended application areas

• Eurospher II Chiral NR columns are able to separate analytes with an oxygen at or near the chiral center and additionally an aromatic ring.

Stationary phase Eurospher II Chiral NR (NR-R) is provided in these column types: analytical, semi-preparative and preparative.

Eurospher II Chiral NR and NR-R Preparative Standard Columns are available with these parameters:

• Column length (mm): 150, 250
• Column ID (mm): 20, 30
• Particle size (µm): 8, 12

KNAUER Chiral HPLC Columns

For analytical, preparative and SMB chiral separations

• Column Brand
  • Eurospher II
• Reversed Phase Modifications
  • Chiral NR-R
  • Chiral AM-R
  • Chiral OM-R
• Normal Phase Modifications
  • Chiral NR
  • Chiral AM
  • Chiral OM
• Flexibility: Wide selection of column and particle sizes, for preparative and analytical applications
• Expandable: Upscaling even for continuous SMB
• Application Service: We offer a customized screening service for your analytes. You will receive an optimal column recommendation including the method parameters.

Eurospher II Chiral

Based on ultra-high purity silica, the Eurospher II chiral column materials are characterized by high enantioselectivity and loadability. 

Available in a wide range of dimensions for analytical, preparative and SMB (simulated moving bed) applications, Eurospher II Chiral columns are the perfect choice for even the most challenging enantioseparation tasks 

Since chiral separations are not very well predictable, KNAUER offers a chiral screening service for your samples (Article number: AL0220).

KNAUER: Eurospher II chiral

Tip: Some of the most popular eluents for HPLC (such as acetone, chloroform, DMF, DMSO, MEK, toluene, dioxane, ethyl acetate, methylene chloride, pyridine and THF) which may be remaining in your HPLC system, can destroy Eurospher II Chiral AM and OM phases even in small concentrations! It is highly recommended that the HPLC system is flushed with appropriate eluents before the installation of the chiral column.