<h3><a target="_blank" rel="noopener noreferrer" href="https://www.isc2026.org/">ISC 2026</a></h3>The <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/314">International Symposium on Chromatography (ISC)</a> represents the oldest conference series on separation science. ISC symposia have been organised since 1956 in each even year. ISC is one of the premier meetings series for discussion of all modes of chromatography and separation science with a broad coverage of techniques and applications.The major focus of the symposium will be on the impact of chromatography and separation science to meet the needs of the pharmaceutical, environmental, food and health industry, as well as science and medicine. The symposium programme will reflect these themes and highlight new challenges and emerging opportunities for the science and marketing of separation and detection systems and methods.As an integral part of the scientific programme of lectures and poster sessions, an international exhibition and vendor seminars on instrumentation and services for chromatography, separation science and mass spectrometry will be organised. ISC 2026 will provide the perfect forum for attendees from academia, industry and government research institutions for scientific exchange and networking.<h3>REGISTRATION</h3><blockquote>👉<a target="_blank" rel="noopener noreferrer" href="https://www.czech-in.org/cmPortalV15/Account/Login?ReturnUrl=%2FcmPortalV15%2FPortal%2FISC26%2Fnormal">Register NOW and do not miss the deadline</a><ul><li>Early-bird registration &amp; payment deadline: May 15, 2026</li><li>Payment deadline for authors of oral presentations: May 15, 2026</li></ul></blockquote><h3>TUTORIAL LECTURES</h3><h5>Bezhan Chankvetadze</h5>Bezhan Chankvetadze is Professor for Physical Chemistry and director of the Institute of Physical and Analytical Chemistry at the Tbilisi State University in Tbilisi, Georgia.He is the Editor-in-Chief of the Journal of Pharmaceutical and Biomedical Analysis and a member of the editorial boards several international journals.Chankvetadze is the recipient of “2006 Belgian Society of Pharmaceutical Science Award of Recognition”, the joint Csaba Horvath Memorial Award of the Hungarian Separation Science Society and Connecticut Separation Science Council, USA (2017) and Nernst-Tswett Award from the European Separation Science Society (EuSSS) (2024).<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ISC_Bezhan_Chankvetadze_b97143b6b0.jpg" alt="ISC 2026: Bezhan Chankvetadze" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ISC_Bezhan_Chankvetadze_b97143b6b0.jpg 156w," sizes="100vw" width="480" height="480"><h5>Martin Gilar</h5>Dr. Martin Gilar received his Ph.D. in analytical chemistry from Institute of Chemical Technology in Prague (1996). He spent postdoc years in Hybridon Inc. (1996-1998) and Northeastern University in Boston (1998) developing separation methods for antisense oligonucleotides and fraction collector for DNA molecules. Since 1998 he has worked at Waters Corp. in Milford, Massachusetts, participating in column, sample preparation and instrument research.Dr. Martin Gilar is a Research Fellow in the Separations R&amp;D group at <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/325">Waters Corporation</a>. He has 30+ years of experience in the separation sciences, including chromatography, electrophoresis, and mass spectrometry. His research interest is the analysis of biopolymers, peptides, and nucleic acids. He has published over 75 peer reviewed papers. Dr. Gilar is recipient of Jaroslav Janak 2022 medal and Chromatographic Society Jubilee medal in 2023.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ISC_Martin_Gilar_3545a57ff2.jpg" alt="ISC 2026: Martin Gilar" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ISC_Martin_Gilar_3545a57ff2.jpg 156w," sizes="100vw" width="480" height="480"><h5>Václav Kašička</h5>Václav Kašička is head of Laboratory of Electromigration Methods (www.uochb.cz/kasicka) at the <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/62">Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences</a> since 1995. He is engaged in development of electroseparation methods and their application for analysis and characterization of (bio)molecules. He is (co)author of 200 papers in impacted journals, 20 book chapters, and 160 lectures at international symposia, with 4922 citations, h-index 39. He is associated editor of the Journal of Separation Science, and member of editorial boards of Electrophoresis, J. Chromatogr. A and other journals. He is chair of Chromatography and Electrophoresis Group of the Czech Chemical Society, and member of permanent Scientific Committees of International Symposia ITP YYYY and LACE YYYY.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ISC_Vaclav_Kasicka_520987cd65.jpg" alt="ISC 2026: Václav Kašička" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ISC_Vaclav_Kasicka_520987cd65.jpg 156w," sizes="100vw" width="480" height="480"><h5>Jörg P. Kutter</h5>Professor Dr. Jörg P. Kutter holds a B.Sc. and a Ph.D. in analytical chemistry (1995) from the University of Ulm, Germany, focusing on chromatographic and electrophoretic techniques.After graduation, he was a postdoctoral fellow at Oak Ridge National Laboratory (Oak Ridge, TN, USA) developing microchip-based analytical tools. He joined the Technical University of Denmark (DTU) in 1998, and in 2006, he was appointed professor in experimental lab-on-a-chip systems.Since September 2013, Dr. Kutter is the Chair of Analytical Biosciences at the Dept. of Pharmacy at the University of Copenhagen. His research interests focus on the development of miniaturized separation and sample preparation methods.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ISC_Joerg_P_Kutter_15b28eb930.jpg" alt="ISC 2026: Jörg P. Kutter" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ISC_Joerg_P_Kutter_15b28eb930.jpg 156w," sizes="100vw" width="480" height="480"><h5>John A. McLean</h5>John A. McLean is Dean of Research Graduate Education, Stevenson Professor of Chemistry, and Director of the Center for Innovative Technologies at Vanderbilt University. McLean and colleagues have focused on the conceptualization, design, and construction of ion mobility and structural mass spectrometers, specifically targeting complex samples in systems, synthetic, and chemical biology. His group applies these strategies to forefront translational research areas in drug discovery, personalized medicine, and ‘human-on-chip’ synthetic biology platforms. He is an elected Fellow of NAI, AAAS, RCS, and ASMS and has published over 200 manuscripts and received over 30 patents in these and allied areas.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ISC_John_A_Mc_Lean_62fe6879ae.jpg" alt="ISC 2026: John A. McLean" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ISC_John_A_Mc_Lean_62fe6879ae.jpg 156w," sizes="100vw" width="480" height="480"><h5>Peter Schoenmakers</h5>Peter Schoenmakers has been a full-time professor in Analytical Chemistry at the University of Amsterdam since 2002, investigating many aspects of one- and two-dimensional chromatography, with a special interest in macromolecules and computer-assisted method development.Together with Bob Pirok, Peter Schoenmakers has recently completed a new textbook on Analytical Separation Science. He has received a number of international awards, most recently the ACS Award for Chromatography (2022) and the LCGC lifetime-achievement award (2023). He received royal recognition when he became Knight in the Order of the Dutch Lion in 2022.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ISC_Peter_Schoenmakers_6962648388.jpg" alt="ISC 2026: Peter Schoenmakers" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ISC_Peter_Schoenmakers_6962648388.jpg 156w," sizes="100vw" width="185" height="185"><h5>František Švec</h5>Frantisek Svec is working at the Faculty of Pharmacy at Charles University in Hradec Kralove, Czech Republic. He has authored over 560 publications, which have been cited more than 25,000 times, giving him an h-index of around 100. F. Svec is best known for his research on monoliths and their use in many different applications. Currently, he is focusing on developing novel formats of sorbents for sample preparation.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ISC_Frantisek_Svec_9413f4a131.jpg" alt="ISC 2026: František Švec" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ISC_Frantisek_Svec_9413f4a131.jpg 156w," sizes="100vw" width="480" height="480">

Tutorial Lectures at ISC 2026

Don't miss this unique opportunity to stand out at the upcoming HTC-19 conference by winning the HTC Tube competition! Deadline for submissions is coming up soon on Friday 15 May! The winners get 750 Euro (first prize), 500 Euro (second prize) and 250 Euro (third prize). That's a lot of Belgian Beer!<h4>Criteria for evaluation</h4><ul><li>We invite scientists to create short videos (up to 3 minutes) that showcase how your chromatography work impacts the world.&nbsp;</li><li>No need for professional editing, just grab your smartphone and start filming.&nbsp;</li><li>Best video will be selected via electronic audience poll, based on scientific content, entertainment value, creativity and technical skills.</li></ul><h4>Who can participate?</h4><ul><li>Eligibility: Scientists (academic or industrial) of any age involved in research projects related to the liquid chromatography workflow (before, during, or after).</li><li>Submissions: Both individual and group submissions are welcome. The video must be based on the presenter’s own findings or work.</li></ul><h4>Deadline and how to submit?</h4><ul><li>Deadline: Friday 15 May 2026</li><li>Please send your submission to info@htc-19.com</li></ul>

HTC Tube Competition at the 19th International Symposium on Hyphenated Techniques in Chromatography and Separation Technology (HTC-19)

<h4>Advancing Glycoproteomics with Flexible LC-MS at the University of Washington</h4>Understanding how cells communicate, migrate, and interact with the immune system often comes down to what is happening on their surface. For Nick Riley, Assistant Professor at the University of Washington, that surface is defined by glycans, complex sugar structures attached to proteins that play a critical role in health and disease.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_What_Happens_When_Glycoproteomics_Meets_Real_Time_LC_MS_Decision_Making_7f77f81741.jpeg" alt="Thermo Fisher Scientific: What Happens When Glycoproteomics Meets Real-Time LC-MS Decision Making?: Nick Riley, Assistant Professor Department of Chemistry, University of Washington, head of the Riley Group." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_What_Happens_When_Glycoproteomics_Meets_Real_Time_LC_MS_Decision_Making_7f77f81741.jpeg 208w," sizes="100vw" width="1024" height="768">The <a target="_blank" rel="noopener noreferrer" href="https://www.riley-research.com/">Riley Group</a> operates at the intersection of glycobiology and mass spectrometry, developing new analytical methods to answer biological questions that were previously out of reach. Based out of one of the largest mass spectrometry hubs in the United States, the lab relies on a high-performance LC-MS workflow built around the <a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/content/lifetech/global/en/home/industrial/mass-spectrometry/liquid-chromatography-mass-spectrometry-lc-ms/lc-ms-systems/orbitrap-lc-ms/orbitrap-tribrid-mass-spectrometers/orbitrap-ascend-tribrid-mass-spectrometer/systems/orbitrap-ascend-multiomics-tribrid-mass-spectrometer.html">Thermo Scientific Orbitrap Ascend MultiOmics Tribrid Mass Spectrometer</a> coupled with a <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/398">Thermo Scientific Vanquish Neo UHPLC System</a>.Together, these platforms deliver flexible, reproducible separations and enable the integration of ETD, HCD, PTCR, and high-mass analysis within a single experiment. This flexibility is critical when working with limited or precious samples such as enriched cell surface glycoproteins, providing the sensitivity and robustness needed to characterize highly complex glycopeptides and intact glycoproteins.<h3>From forensics to glycoproteomics</h3>Riley’s scientific path began in undergraduate chemistry and psychology, where an early interest in forensics led him to mass spectrometry. Rather than focusing on applications, he became interested in the instruments themselves.That fascination took him to the University of Wisconsin-Madison, where he trained in Josh Coon’s lab and worked extensively on electron transfer dissociation. While developing new fragmentation methods, Riley encountered glycopeptides almost by accident and quickly realized their complexity and importance.A postdoctoral position in Carolyn Bertozzi’s lab at Stanford deepened his exposure to glycobiology and reinforced his interest in building tools that allow scientists to better interrogate biological systems. That philosophy now defines his research program at the University of Washington.<h3>Why flexibility matters in glycoproteomics</h3>Glycoproteomics presents unique analytical challenges. Glycans increase molecular heterogeneity, complicate ionization, and require multiple fragmentation strategies to fully characterize.“There’s no single method that can answer all of our questions,” Riley explains. “We need flexibility at every level.”For the Riley Group, that flexibility comes from advanced LC-MS platforms, particularly Tribrid instruments like the Orbitrap Ascend Mass Spectrometer. These systems allow his team to combine ETD, HCD, PTCR, and high-mass analysis within a single workflow.That versatility is essential when working with limited samples, especially in experiments involving cell surface glycoproteins or double enrichment strategies.<h3>Turning technology into biological insight</h3>One recent study highlights how instrumentation directly enables discovery. Riley’s team investigated how glycosylation affects protein corona formation using SEER nanoparticles. The workflow required two enrichment steps, leaving very little material for analysis.Using the Orbitrap Ascend Mass Spectrometer’s real-time library search capabilities, the team developed Autonomous Dissociation Type Selection, a method that uses real-time decision making to determine the optimal fragmentation method during acquisition. This approach allowed the team to extract comprehensive information from a single LC-MS injection, preserving sample while accelerating discovery.“That kind of experiment simply wouldn’t be possible without real-time decision making on the instrument,” says Riley.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_What_Happens_When_Glycoproteomics_Meets_Real_Time_LC_MS_Decision_Making_2_f5c7de51c3.jpeg" alt="Thermo Fisher Scientific: What Happens When Glycoproteomics Meets Real-Time LC-MS Decision Making?: Kayla Markuson, B.S., is one of the grad students in the Riley Group. She was recipient of the 2025 Thermo Scientific Quantitative Proteomics Research Grant Program." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_What_Happens_When_Glycoproteomics_Meets_Real_Time_LC_MS_Decision_Making_2_f5c7de51c3.jpeg 208w," sizes="100vw" width="1024" height="768"><h3>Lowering barriers, training scientists</h3>Beyond enabling specific experiments, Riley sees advanced instrumentation as a way to democratize complex methodologies. Techniques like ETD, once difficult to reproduce, are now robust and accessible.That shift has a direct impact on training. Students in Riley’s lab are encouraged to design experiments around unanswered biological questions rather than technical constraints.“When the instrument isn’t the bottleneck, creativity becomes the skill you’re really teaching,” he notes. “That’s how you prepare scientists for the future.”<h3>Looking ahead</h3>As instrumentation continues to evolve, Riley believes the next breakthroughs will come from increased sensitivity, richer fragmentation strategies, and smarter data analysis. The ultimate goal is not just better measurements, but deeper biological understanding.“Glycoproteomics demands multiple analytical strategies,” Riley explains. “We need to move seamlessly between different fragmentation methods, mass ranges, and separation conditions. The Ascend paired with the Vanquish Neo gives us that freedom.”“Technology should expand the questions we can ask,” he says. “That’s when real discovery happens.”&nbsp;<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_What_Happens_When_Glycoproteomics_Meets_Real_Time_LC_MS_Decision_Making_3_ced9ad52e2.jpeg" alt="Thermo Fisher Scientific: What Happens When Glycoproteomics Meets Real-Time LC-MS Decision Making?: Lab members pictured left to right in front of Riley Group’s Thermo Scientific Orbitrap Ascend MultiOmics Tribrid Mass Spectrometer coupled with a Thermo Scientific Vanquish Neo UHPLC System: Nick Riley, Emmajay Sutherland, Jacob Russell, Tim Veth, Kayla Markuson." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_What_Happens_When_Glycoproteomics_Meets_Real_Time_LC_MS_Decision_Making_3_ced9ad52e2.jpeg 208w," sizes="100vw" width="768" height="576"><blockquote>Visit us on&nbsp;<a target="_blank" rel="noopener noreferrer" href="https://www.linkedin.com/showcase/72003132/admin/dashboard/">LinkedIn:</a>&nbsp;#Glycoproteomics #MassSpectrometry #LCMS</blockquote>

What Happens When Glycoproteomics Meets Real-Time LC-MS Decision Making?

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The International Symposium on Chromatography (ISC) represents the oldest conference series focussing on separation science. ISC symposia have been organised since 1956 in each even year. ISC is internationally recognised as one of the premier meeting series for discussion of all modes of chromatography and separation science with a broad coverage of techniques and applications.

International Symposium on Chromatography - (ISC)

The HTC symposium series started in 1990 and is the ideal meeting place for scientists and practitioners from academia and industry and vendors to discuss and gather new insights in emerging technologies, instrumentation, workflows, and applications. Organized under the auspices of the Vrije Universiteit Brussel (VUB), the Catholic University of Leuven (KU Leuven), Ghent University (UGhent), and the Separation Science Group of the Royal Society of Chemistry (RSC), HTC-19 is expected to gather over 300 participants.

International Symposium on Hyphenated Techniques in Chromatography and Separation Technology

Thermo Scientific TSQ Altis Plus EFOX Edition Triple Quadrupole Mass Spectrometer

Thermo Scientific TSQ Altis Plus EFOX Edition is a triple quadrupole mass spectrometer designed for ultra-sensitive quantification of trace contaminants in environmental and food safety analyses.

The Thermo Scientific™ TSQ Altis™ Plus EFOX Edition is a triple quadrupole mass spectrometer engineered for the most demanding environmental and food safety applications. Combining extreme sensitivity, high acquisition speed, and robust system design, it enables accurate detection and quantification of trace contaminants even in highly complex matrices.When integrated with advanced <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products?category=37&amp;manufacturerItems=3">(U)HPLC systems</a>, dedicated quantitation software, and optimized sample preparation workflows, the system delivers reliable, compliant-ready results. Its intuitive operation and seamless software integration enhance laboratory productivity and analytical confidence.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_TSQ_Altis_Plus_EFOX_Edition_Triple_Quadrupole_Mass_Spectrometer_4354bbb447.jpg" alt="Thermo Scientific TSQ Altis Plus EFOX Edition Triple Quadrupole Mass Spectrometer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_TSQ_Altis_Plus_EFOX_Edition_Triple_Quadrupole_Mass_Spectrometer_4354bbb447.jpg 207w," sizes="100vw" width="650" height="490"><h4>Key features</h4><ul><li>Extreme sensitivity for trace-level contaminant detection in environmental and food matrices</li><li>Exceptional robustness ensuring reliable, reproducible results and maximum uptime</li><li>Ultrafast SRM acquisition enabling higher compound throughput</li><li>High-selectivity H-SRM performance (0.2 Da FWHM) for improved signal-to-noise and confident target identification</li><li>Seamless integration with application-specific software to boost productivity</li><li>Intuitive operation delivering high-quality, defensible results regardless of user experience</li></ul><h4>Technical specifications</h4><ul><li>Mass range: 2–2010 m/z</li><li>Ion source: OptaMax NG</li><li>Technique: MS</li><li>Software compatibility: <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/76">Chromeleon software</a></li><li>Dimensions (D × W × H): 840 × 760 × 680 mm</li><li>Weight: 125 kg</li><li>System type: TSQ LC-MS with dry pump</li><li>Applications: Environmental analysis, food safety testing</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_TSQ_Altis_Plus_EFOX_Edition_Triple_Quadrupole_Mass_Spectrometer_2_4c34dd7919.jpg" alt="Thermo Scientific TSQ Altis Plus EFOX Edition Triple Quadrupole Mass Spectrometer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_TSQ_Altis_Plus_EFOX_Edition_Triple_Quadrupole_Mass_Spectrometer_2_4c34dd7919.jpg 220w," sizes="100vw" width="650" height="460">

Thermo Scientific Orbitrap Exploris EFOX Mass Detector

Orbitrap Exploris EFOX is an HRMS detector for screening, quantification, and profiling of trace contaminants in food and environmental analysis using full-scan acquisition and in-source CID.

The Thermo Scientific™ Orbitrap Exploris™ EFOX Mass Detector is an Orbitrap-based mass detector designed for accurate and reliable trace contaminant analysis in environmental and food safety applications. This high-resolution mass spectrometry system enables comprehensive screening, quantification, and sample profiling within a single analysis while supporting efficient laboratory workflows and regulatory compliance.The instrument combines high sensitivity, selectivity, and robust design with simplified workflows for both routine and advanced applications. Full-scan acquisition together with in-source fragmentation eliminates the need for time-consuming MS/MS method optimization. Integration with <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/76">Thermo Scientific™ Chromeleon™ software</a> ensures efficient data processing and management.<h4>Key features</h4><ul><li>High-resolution mass spectrometry for precise detection and quantification of trace contaminants</li><li>Supports targeted analysis, suspect screening, and comprehensive sample profiling</li><li>Streamlined workflows reducing operational and maintenance costs</li><li>Enables retrospective data analysis without sample reinjection</li><li>Integrated with Chromeleon™ CDS for efficient data processing</li></ul><h4>Technical specifications</h4><ul><li>Dimensions (D × W × H): 763 × 534 × 703 mm (30 × 21 × 27.6 in), without data system, vacuum rough pumps, and optional items</li><li>Mass accuracy:<ul><li>External calibration: &lt;3 ppm RMS drift over 24 h</li><li>1-point calibration: &lt;3 ppm RMS drift over at least 4 weeks</li><li>Internal lock mass: &lt;1 ppm RMS drift over 24 h</li><li>EASY-IC: &lt;1 ppm RMS drift for at least 5 days</li></ul></li><li>Mass resolution: Up to 90,000 at 200 m/z</li><li>Scan rates: Up to 22 Hz at resolution setting 15,000</li><li>Software compatibility: Chromeleon software</li><li>Weight: 120 kg (265 lbs)</li><li>Mass range: 50–1500 m/z</li><li>Technique: MS</li><li>Type: Orbitrap LC-MS</li><li>Unit size: Each</li></ul>

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What Happens When Glycoproteomics Meets Real-Time LC-MS Decision Making?

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Tutorial Lectures at ISC 2026