<div><div><div>Scientists at IOCB Prague have developed a breakthrough technology that streamlines aptamer development. The new method integrates several biochemical and bioinformatics steps and paves the way for new diagnostic and therapeutic applications. Ongoing applications include wearable sensors that monitor selected biomarkers in real time and provide early warnings of impending health complications. The findings were published in Nature Communications.</div></div><div>Aptamers are short DNA or RNA strands that can recognize and bind to a specific target molecule with high precision. Similar to antibodies, they can be used to detect these molecules or modulate their activity. Unlike antibodies, they are much more stable, can be produced synthetically, and can be chemically modified to achieve the desired properties. As a result, they can offer capabilities that cannot be achieved with antibodies.</div><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/UOCHB_Nova_technologie_inovuje_vyvoj_aptameru_syntetickych_alternativ_protilatek_2_81e99b9900.jpg" alt="IOCHB Prague: New technology streamlines the development of aptamers, synthetic alternatives to antibodies: Chemically modified DNA aptamer bound to the target protein." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_UOCHB_Nova_technologie_inovuje_vyvoj_aptameru_syntetickych_alternativ_protilatek_2_81e99b9900.jpg 228w," sizes="100vw" width="1343" height="916">As demand grows for accurate and rapid diagnostic tools, aptamers are often better suited to these applications than antibodies. However, developing aptamers is both experimentally demanding and time-consuming. A team of scientists from IOCB Prague, led by Dr. Marek Ondruš and <a target="_blank" rel="noopener noreferrer" href="https://hocek.group.uochb.cz/en">Prof. Michal Hocek</a>, has now developed a technology that significantly shortens the development process.“Developing an aptamer is often like looking for a needle in a haystack. Among trillions of different DNA sequences, we search for the one that binds strongly and specifically to a target molecule. Our new approach first screen for ‘aptamer families’ – hundreds of related sequences – and then identify the best-performing member of the family. This approach can reduce development time from several months to only a few days,” says Marek Ondruš.<blockquote>Video:<a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/watch?v=_3zXUeVMugU"> New technology streamlines the development of aptamers, synthetic alternatives to antibodies&nbsp;</a></blockquote>The team has also expanded the potential applications of aptamers by chemically modifying their building blocks. For example, introducing functional groups similar to those found naturally in amino acids allows the resulting molecules to combine the advantages of both DNA and antibodies: Their sequence is encoded by the order of nucleotides in DNA, while the attached chemical modifications greatly expand their ability to recognize biologically relevant targets and mimic interactions between proteins that are underlying many biological processes.The researchers demonstrated the potential of this new method using the human insulin receptor, a key protein that regulates blood sugar levels. They developed an aptamer that specifically binds to the receptor and elucidated the molecular basis of this interaction using cryo-electron microscopy. “We have shown that chemically introduced functional groups play a crucial role not only in target recognition and formation of the aptamer–protein complex, but also in stabilizing the DNA aptamer’s structure. Our findings provide new insights into how chemically modified nucleic acids can mimic key properties of proteins,” says Marek Ondruš.In the future, the technology could complement – or, in some applications, even replace – antibody-based diagnostic tools. Researchers are collaborating with <a target="_blank" rel="noopener noreferrer" href="http://iocbtech.cz/">IOCB Tech</a> on its further development, as the company helps to bring discoveries from IOCB Prague into practical applications.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/UOCHB_Nova_technologie_inovuje_vyvoj_aptameru_syntetickych_alternativ_protilatek_9694c21671.jpg" alt="IOCHB Prague/Tomáš Belloň: New technology streamlines the development of aptamers, synthetic alternatives to antibodies: Dr. Marek Ondruš, first author of the study, and Prof. Michal Hocek, head of the Bioorganic and Medicinal Chemistry of Nucleic Acids research group at IOCB Prague." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_UOCHB_Nova_technologie_inovuje_vyvoj_aptameru_syntetickych_alternativ_protilatek_9694c21671.jpg 234w," sizes="100vw" width="2000" height="1335"><blockquote><h4>Original article</h4><h4><a target="_blank" rel="noopener noreferrer" href="https://www.nature.com/articles/s41467-026-73676-y#citeas">Expedient single-round selection of hyper-modified aptamer targeting insulin receptor from over-represented dually nucleobase-modified DNA libraries</a></h4>ablo Alberto Franco-Urquijo, Marek Ondruš, Jaroslav Kurfürst, Jana Škerlová, Irena Selicharová, Lucie Mužíková Čechová, Hana Šváchová, Alena Semerádtová, Anatolij Filimoněnko, Adéla Fejfarová, Jiří Homola, Tomáš Kouba &amp; Michal HocekNat. Commun., 2026<a target="_blank" rel="noopener noreferrer" href="https://doi.org/10.1038/s41467-026-73676-y">https://doi.org/10.1038/s41467-026-73676-y</a>&nbsp;<h6>licenced under <a target="_blank" rel="noopener noreferrer" href="https://creativecommons.org/licenses/by/4.0/">CC-BY 4.0</a></h6></blockquote><h4>Abstract</h4>Discovery of functional nucleic acids from randomized libraries typically relies on multiple, time-consuming iterative rounds of in vitro selection with low success rate. Here, we present a single-round selection strategy for rapid screening of multiple over-represented nucleobase-modified DNA libraries and various selection conditions, capable of identifying high-affinity modified aptamers. Double partition followed by amplification of eluted sequences, NGS analysis and clustering provides fast identification of aptamer candidates. Screening of modified DNA libraries containing modified adenine and uracil nucleotides bearing hydrophobic aromatic phenyl and indole moieties results in development of an aptamer binding human insulin receptor with sub-nanomolar affinity and exquisite specificity. Cryo-EM structure reveals the importance of each aromatic modification, either in stabilizing the secondary structure or facilitating interactions with the protein surface. This approach addresses the main drawbacks of aptamer selection and has potential for high-throughput screening and accelerating the development of next-generation aptamers for diagnostics or therapeutics.</div>

New technology streamlines the development of aptamers, synthetic alternatives to antibodies

Clarity 10.2 expands instrument control capabilities with new control modules and updates the MS extension to help you work more efficiently.<h4><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/999">Clarity</a> 10.2 highlights</h4><ul><li>New and updated control modules</li><li>Improved MS data import and export</li><li>Obsolete hardware support ended</li></ul><h4>Instrument control modules</h4>Clarity 10.2 introduces new instrument control modules from Annuo (AS-3117, FAS-3823) and updated instrument controls form Sykam and Ecom.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_Instrument_control_modules_5de26782b0.jpg" alt="DataApex: Instrument control modules" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Data_Apex_Instrument_control_modules_5de26782b0.jpg 228w," sizes="100vw" width="380" height="260"><h4>MS data import/export improvements</h4>Clarity improves MS data exchange, especially for *.cdf files. MS instruments now support export and import of multiple spectral data and non-spectral signal data in the same CDF file. Import also better handles uniform sampling information, m/z Step values, scale factors, and file names with non-ASCII characters. Exporting individual chromatogram signals from MS instruments is now available through a separate Export Chromatogram dialog.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_MS_data_import_export_improvements_a7967a4020.jpg" alt="DataApex: MS data import-export improvements" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Data_Apex_MS_data_import_export_improvements_a7967a4020.jpg 228w," sizes="100vw" width="378" height="259"><h4>Obsolete hardware support terminated</h4>Due to changes in Windows driver security requirements, this update discontinues support for obsolete hardware, including INT7, INT9, U-PAD, U-PAD2, and CB20.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_Obsolete_hardware_support_terminated_24d9329419.jpg" alt="DataApex: Obsolete hardware support terminated" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Data_Apex_Obsolete_hardware_support_terminated_24d9329419.jpg 228w," sizes="100vw" width="378" height="259"><blockquote>Explore the complete list of all changes, fixes, and additions in version 10.2.👉<a target="_blank" rel="noopener noreferrer" href="https://www.dataapex.com/version_history?product=1">See the complete changelog&nbsp;</a></blockquote>

Clarity Chromatography Software 10.2 released!

🎤Dr. Leigh Terry (University of Alabama)In this episode of Concentrating on Chromatography, we sit down with Dr. Leigh Terry from the University of Alabama to explore one of the biggest challenges in environmental analysis today: understanding—and accurately measuring—PFAS in water systems.While most regulatory methods focus on a small number of compounds like PFOA and PFOS, there may be thousands of PFAS compounds in the environment—and much of that burden goes undetected.<h4>In this episode, we cover:</h4><ul><li>Why PFAS are called “forever chemicals” (and why that label is evolving)</li><li>The limitations of targeted LC-MS/MS methods</li><li>What the fluorine mass balance problem reveals about PFAS destruction</li><li>How combustion ion chromatography (CIC) helps measure total organofluorine</li><li>Why “99.99% removal” doesn’t always mean what you think</li><li>Where PFAS actually end up in wastewater treatment systems</li><li>The most effective technologies for PFAS removal today</li><li>Why drinking water may only account for ~20% of total PFAS exposure</li></ul><h4>Key Insight:</h4>Even when analyzing dozens of PFAS compounds, researchers may only be capturing a small fraction of total organic fluorine—raising major questions about how we monitor and regulate these contaminants.<h3>Video Transcription</h3>In this episode of Concentrating on Chromatography, Dr. Leigh Terry discusses PFAS contamination in drinking water, the analytical challenges associated with measuring these compounds, current treatment technologies, and future directions for monitoring and regulation. The conversation highlights how analytical chemistry, environmental engineering, and public health intersect in addressing one of today's most discussed classes of emerging contaminants.<h4>Understanding PFAS and Their Significance</h4><h5>The University of Alabama Water Quality Research Center</h5>Dr. Leigh Terry is part of the University of Alabama's Center for Water Quality Research. The center operates an analytical laboratory focused on drinking water quality and the detection of contaminants at extremely low concentrations.The laboratory specializes in:<ul><li>Drinking water analysis</li><li>Organic contaminants</li><li>Emerging contaminants</li><li>PFAS monitoring</li><li>Water quality research</li></ul>Their work supports both research initiatives and practical solutions for water utilities and environmental agencies.<h4>Why Focus on PFAS?</h4>Although PFAS compounds have existed since the 1940s, public awareness has increased dramatically only in recent years.According to Dr. Terry, several factors contributed to the rapid growth of PFAS research:<ul><li>Increased media attention</li><li>New regulatory initiatives</li><li>Growing evidence of human exposure</li><li>Expanding research opportunities</li><li>Greater understanding of potential health risks</li></ul>PFAS are not new contaminants. Rather, society is only beginning to understand their prevalence in the environment and their potential impacts on human health.<h4>The Development of Standardized PFAS Methods</h4>One major advancement in PFAS analysis has been the development of standardized EPA methods.These methods allow:<ul><li>Consistent testing procedures</li><li>Comparable results between laboratories</li><li>Regulatory monitoring</li><li>Reliable data interpretation</li></ul>Dr. Terry notes that many of these standardized approaches began appearing around 2018–2019, providing a common framework for analytical laboratories and researchers.<h4>How Large Is the PFAS Universe?</h4>Many people are familiar with PFOA and PFOS, two of the most heavily studied PFAS compounds. However, these represent only a small fraction of the broader PFAS family.PFOA and PFOS are often referred to as:<ul><li>Legacy PFAS compounds</li><li>Original PFAS contaminants</li><li>Early commercial PFAS chemicals</li></ul>The challenge is that even minor modifications to molecular structure create entirely new PFAS compounds.Researchers estimate:<ul><li>Thousands of PFAS compounds exist</li><li>Some estimates exceed 10,000 compounds</li><li>Exact numbers depend on how PFAS are defined</li></ul>Scientific debate continues regarding classification and definition, making precise counting difficult.<h4>Why PFAS Are Called "Forever Chemicals"</h4>Dr. Terry notes that the phrase "forever chemicals" has become widely used, although she suggests the terminology could benefit from rebranding.PFAS persistence results from two key chemical properties.<h5>1. Amphiphilic Structure</h5>PFAS molecules contain:<ul><li>A water-loving (hydrophilic) head group</li><li>A water-repelling (hydrophobic) fluorinated tail</li></ul>This unusual combination allows PFAS to partition between:<ul><li>Water</li><li>Solids</li><li>Air-water interfaces</li><li>Foam</li></ul>Unlike many organic compounds, PFAS can interact effectively with multiple environmental phases.<h5>2. Extremely Strong Carbon–Fluorine Bonds</h5>The carbon–fluorine bond is among the strongest bonds in organic chemistry.As Dr. Terry explains:<ul><li>Large amounts of energy are required to break these bonds</li><li>Natural degradation processes are often ineffective</li><li>Destruction can require highly aggressive treatment conditions</li></ul>These properties make PFAS extremely persistent in both environmental systems and biological organisms.<h4>Toxicity, Regulations, and Environmental Behavior</h4><h5>Understanding PFAS Toxicity</h5>One of the biggest challenges in PFAS regulation is the incomplete understanding of toxicity.Dr. Terry explains that EPA regulations generally consider three factors:<ul><li>Presence in drinking water sources</li><li>Toxicity to humans</li><li>Availability of practical treatment options</li></ul>While some PFAS compounds are known to be harmful, many others remain insufficiently studied. Furthermore, PFAS often occur as mixtures rather than individual compounds.This creates important scientific questions:<ul><li>What is the toxicity of individual PFAS?</li><li>What is the toxicity of PFAS mixtures?</li><li>How should cumulative exposure be evaluated?</li></ul>These uncertainties continue to drive active research.<h4>What Happens to PFAS in Wastewater Treatment Plants?</h4>PFAS do not behave like many conventional contaminants.Rather than remaining fully dissolved in water, they often accumulate at interfaces such as:<ul><li>Water-solid interfaces</li><li>Water-air interfaces</li><li>Foam layers</li><li>Biological solids</li></ul>As a result:<ul><li>Some PFAS accumulate in biosolids</li><li>Some partition into foam</li><li>Some remain in treated effluent</li></ul>Their distribution depends on wastewater composition and treatment processes.<h4>Regulatory Monitoring and Targeted LC-MS Analysis</h4>Current EPA regulations focus on targeted analysis of specific PFAS compounds.Examples include:<ul><li>PFOA</li><li>PFOS</li></ul>Drinking water regulations currently establish maximum contaminant levels (MCLs) for these compounds at extremely low concentrations.Advantages of targeted LC-MS analysis include:<ul><li>Clearly defined analytes</li><li>Established regulatory limits</li><li>High analytical sensitivity</li><li>Reliable quantitation</li></ul>However, limitations remain:<ul><li>Only a small subset of PFAS is measured</li><li>Many PFAS compounds remain undetected</li><li>Total PFAS burden may be underestimated</li></ul>As Dr. Terry notes, targeted analysis provides only part of the overall picture.<h4>The Fluorine Mass Balance Problem</h4>One of the most important concepts discussed in the interview is fluorine mass balance.When PFAS degrade, fluorinated fragments may remain in the environment.This creates a critical question:Are treatment technologies truly destroying PFAS, or merely transforming them into shorter-chain PFAS compounds?To answer this, researchers perform fluorine mass balance calculations using:<ul><li>Targeted PFAS analysis</li><li>Fluoride measurements</li><li>Total organic fluorine measurements</li></ul>A successful destruction process should ultimately convert PFAS into fluoride ions rather than simply producing smaller PFAS molecules.<h4>Advanced Analysis, Treatment Technologies, and Future Directions</h4><h5>Combining Targeted and Bulk Fluorine Measurements</h5>Dr. Terry's group complements targeted LC-MS analysis with measurements of total organic fluorine.Approaches include:<ul><li>Absorbable Organic Fluorine (AOF)</li><li>Extractable Organic Fluorine (EOF)</li><li>Combustion Ion Chromatography (CIC)</li></ul>In these methods:<ul><li>Organic fluorine is captured</li><li>Samples are combusted</li><li>Released fluoride is quantified</li></ul>This provides insight into total fluorinated content, although contributions may originate from sources beyond PFAS, including pharmaceuticals and consumer products.<h4>Surprising Findings from Combined Analysis</h4>One important finding from wastewater studies was that targeted PFAS measurements accounted for only a small fraction of total organic fluorine.Dr. Terry reports that:<ul><li>Approximately 4% of measured AOF could be explained by targeted PFAS compounds</li><li>The majority of organic fluorine remained unidentified</li></ul>This suggests that environmental fluorine chemistry is considerably more complex than currently represented by routine monitoring programs.<h4>Preventing PFAS Contamination in the Laboratory</h4>PFAS analysis requires exceptionally strict quality control.Dr. Terry's laboratory routinely:<ul><li>Tests every new batch of SPE cartridges</li><li>Tests carbon tubes before use</li><li>Uses DI water blanks</li><li>Verifies consumables labeled as PFAS-free</li><li>Collects field blanks</li><li>Monitors analytical blanks throughout workflows</li></ul>These practices help prevent contamination from laboratory materials and consumables, a common challenge in ultra-trace PFAS analysis.<h4>Current PFAS Treatment Technologies</h4>Three technologies currently dominate PFAS removal in drinking water treatment:<ul><li>Granular Activated Carbon (GAC)</li><li>Ion Exchange Resins</li><li>Reverse Osmosis (RO)</li></ul>Selection depends on:<ul><li>PFAS concentration</li><li>Water quality</li><li>Local operating conditions</li><li>Utility infrastructure</li></ul>Although many emerging technologies are being investigated, these remain the most widely implemented solutions.<h4>Membrane Filtration and Pretreatment</h4>Dr. Terry collaborates with colleagues studying membrane-based PFAS treatment.Her own work focuses on pretreatment through biological filtration.The strategy involves:<ul><li>Removing natural organic matter</li><li>Reducing membrane fouling</li><li>Improving membrane performance</li><li>Extending operational efficiency</li></ul>This integrated approach demonstrates how multiple treatment technologies can work together to improve PFAS removal.<h4>Regional Monitoring Projects</h4>The University of Alabama team participates in EPA-supported monitoring efforts along the Gulf Coast.Their observations indicate:<ul><li>PFAS rarely occur alone</li><li>Multiple PFAS compounds frequently co-occur</li><li>Contamination often originates from identifiable point sources</li></ul>Examples include:<ul><li>Industrial facilities</li><li>Manufacturing operations</li><li>Military installations</li><li>Carpet manufacturing facilities</li></ul>Source identification remains a critical component of environmental monitoring programs.<h4>Future Directions for PFAS Monitoring</h4>Looking ahead, Dr. Terry sees several opportunities for improvement.Desired advances include:<ul><li>In situ monitoring technologies</li><li>Portable detection systems</li><li>Reduced analytical complexity</li><li>Lower instrument costs</li><li>Less expensive consumables</li><li>Faster analysis workflows</li></ul>Current PFAS testing requires substantial expertise, specialized instrumentation, and rigorous quality control, making widespread implementation challenging.<h4>Dr. Terry's Perspective on Long-Term Solutions</h4>When asked what major PFAS challenge she would most like to solve, Dr. Terry offered a broader perspective.Rather than focusing solely on remediation, she emphasized prevention.Her view is that society should:<ul><li>Better evaluate chemical toxicity before commercialization</li><li>Assess risks before large-scale deployment</li><li>Reduce introduction of harmful compounds into the environment</li><li>Support utilities tasked with contaminant removal</li></ul>She notes that water utilities often bear the responsibility of removing contaminants they did not create, highlighting the need for broader societal and regulatory support.<h4>Final Thoughts</h4>Dr. Terry encourages consumers to:<ul><li>Learn where their drinking water originates</li><li>Read annual water quality reports</li><li>Stay informed about local water quality</li><li>Consider appropriate home filtration where needed</li></ul>At the same time, she emphasizes confidence in municipal water systems and the importance of continued investment in water quality research, monitoring, and treatment technologies.<h4>Conclusion</h4>PFAS remain one of the most complex challenges in environmental chemistry and water treatment. Through advanced analytical methods such as LC-MS/MS, combustion ion chromatography, fluorine mass balance approaches, and large-scale monitoring programs, researchers like Dr. Leigh Terry are helping improve our understanding of these persistent contaminants.The interview highlights that solving the PFAS challenge will require a combination of better analytical tools, improved treatment technologies, stronger regulatory frameworks, and a greater emphasis on prevention before contaminants enter the environment.<blockquote>This text has been automatically transcribed from a video presentation using AI technology. It may contain inaccuracies and is not guaranteed to be 100% correct.</blockquote><blockquote><h4>Concentrating on Chromatography Podcast</h4>Dive into the frontiers of chromatography, mass spectrometry, and sample preparation with host David Oliva. Each episode features candid conversations with leading researchers, industry innovators, and passionate scientists who are shaping the future of analytical chemistry. From decoding PFAS detection challenges to exploring the latest in AI-assisted liquid chromatography, this show uncovers practical workflows, sustainability breakthroughs, and the real-world impact of separation science. Whether you’re a chromatographer, lab professional, or researcher you'll discover inspiring content!You can find Concentrating on Chromatography Podcast in podcast apps:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://open.spotify.com/show/1wZg67rCjoGju4yhqxI3tL">Spotify</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podcasts.apple.com/tz/podcast/concentrating-on-chromatography/id1788429185">Apple podcast</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podscan.fm/podcasts/concentrating-on-chromatography">podscan</a></li></ul>and on <a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/@ChromatographyTalk/videos">YouTube channel</a></blockquote>

PFAS in Water: Why We’re Missing 96% of the Problem

Article

Product

Video

Scientists

Environment

Water

Interview

Science and research

Software

Since 1991 DataApex develops and manufactures chromatography data stations. DataApex is constantly striving to provide users with efficient and up-to-date tools for chromatography data processing.

DataApex

The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences (IOCB Prague) is a leading scientific institution in the Czech Republic, recognized internationally. Its primary mission is basic research in the fields of chemical biology and medicinal chemistry, organic and material oriented chemistry, chemistry of natural compounds, biochemistry and molecular biology, physical chemistry, theoretical chemistry, and analytical chemistry. 

Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences

Organomation, founded in 1959, designs and manufactures high-quality nitrogen evaporators and extraction systems. Known for innovation and durability, their lab instruments are used globally for efficient sample preparation with strong customer support.

Organomation

Organomation ROT-X-TRACT-LC Extraction System

ROT-X-TRACT-LC is a high-throughput liquid-liquid extraction system supporting simultaneous processing of up to eight samples using Corning Accelerated One-Step apparatuses.

The ROT-X-TRACT-LC system is designed to support up to eight (8) Corning Accelerated One-Step extraction apparatuses, providing an efficient solution for high-throughput liquid-liquid extraction workflows. The Corning Accelerated One-Step extractor integrates extraction and concentration into a single continuous process, helping laboratories streamline sample preparation while reducing manual handling steps.To maintain compatibility with standard laboratory fume hoods, the system utilizes a modified Friedrichs condenser with a reduced overall height. Allihn condensers are also available upon customer request.The hydrophobic membrane enables continuous circulation of the organic solvent through the 1 L sample bottle until extraction is complete. By integrating a stopcock assembly and a 3-ball Snyder column, the Corning One-Step extractor is capable of both analyte extraction and final solvent evaporation within the same operating cycle.The system also includes an electronic side control module that allows users to program bath temperatures and timed operating cycles in accordance with specific analytical methodologies.<ul><li>Multiple Simultaneous Extractions: Extract and concentrate up to eight samples at once</li><li>Easy Sample Access: The instrument rotates allowing all samples to be accessed from the front</li><li>Fewer Connections: One water supply line in, one drain line out</li><li>Precise: Digital control option allows for exact temperature regulation</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Organomation_ROT_X_TRACT_LC_Extraction_System_c7cbab77de.jpg" alt="Organomation ROT-X-TRACT-LC Extraction System" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Organomation_ROT_X_TRACT_LC_Extraction_System_c7cbab77de.jpg 156w," sizes="100vw" width="1400" height="1400"><h3>Standard features</h3><ul><li>Stainless steel construction</li><li>Stepped bath rim and cover disk seals steam chamber</li><li>Each condenser water line attached to centrally located water manifold</li><li>Side control box</li><li>Water flow meter</li><li>Laboratory grade materials stand up to organic solvents</li></ul><h3>Glassware features</h3><ul><li>Stop cock to switch to sample concentration after extraction is complete</li><li>1 L sample bottle</li><li>J-shaped Snyder column</li><li>Hydrophobic Corning membranes (sold separately)</li><li>In-line KD flask for optimum heat transfer</li><li>Vacuum insulated concentrator tube</li></ul><h3>Options (Add to main Cat# when purchasing)</h3><ul><li>All associated glassware</li><li>Positive pressure type Z purged bath (Option Code -Z), Cat# 13318-Z</li><li>240V wiring and plug (Option Code -2), Cat# 13318-2</li></ul><h3>Specifications</h3><ul><li>Instrument Catalog Number: 11318</li><li>Instrument Name: Corning Accelerate One-Step Extractor</li><li>Max No. of Samples: 8</li><li>Bench Space: 24 x 19 x 42 in</li><li>w x d x h: 61 x 48 x 107 cm</li><li>Attached Control Box for Power &amp; Timer: Standard</li><li>Glassware 1000ml: GS3380</li><li>Extractor Type &amp; Size: Corning One-Step 1000 ml</li><li>Solvent Flask Type &amp; Size: In-Line KD 100 ml</li><li>Concentrator Tube: Insulated Tip</li><li>Type &amp; Size: 10 ml 19/22</li><li>Snyder Column Type: J Tube</li><li>Condenser Type: Cold Finger 45/50</li><li>Solvent Collection Flood Extractor: Standard</li><li>Hydrophobic Membrane: Standard</li><li>Water Bath Catalog Number: B3101</li><li>Bath Model Number: 16169</li><li>Bath Inside Dimensions: 16.0 x 8.5 in</li><li>Diameter x Depth: 40.6 x 21.6 cm</li><li>Bath Outside Dimensions: 24 x 19 x 10 in</li><li>w x d x h: 61 x 48 x 25 cm</li><li>Water Flow Meter: 0-3.0 lpm</li><li>Heaters Total Watts: 1600 w</li><li>Bath Temperature Range: 30 - 100 C</li><li>Bath Temperature Accuracy: +/- 2 C</li></ul><h3>Accessories</h3><ul><li>P1332: O-rings for S-EVAP/RXT water manifold</li><li>GA3446C-20: Membranes Corning for Accelerated One-Step extractor, pkg of 20</li><li>All associated glassware</li><li>Bath cover disks &nbsp;</li></ul>

Organomation Teflon-Free N-EVAPs for PFAS Research

Teflon-Free N-EVAP is a nitrogen concentrator for PFAS sample preparation and concentration without the risk of PTFE contamination. It offers individual nitrogen flow control and supports up to 24 samples simultaneously.

Teflon-Free N-EVAP nitrogen evaporators are specifically designed for PFAS sample preparation and concentration workflows in analytical and environmental laboratories. Built entirely without PTFE or other fluoropolymers, these systems help minimize the risk of contamination during nitrogen blowdown evaporation while enabling simultaneous processing of multiple samples.Referenced in EPA PFAS methods 533, 537.1, and 1633, the Teflon-Free N-EVAP models are widely used in environmental and research laboratories requiring reliable PFAS sample preparation. The systems support both 15 mL and 50 mL centrifuge tubes and feature individual needle valves for each sample position, allowing independent nitrogen flow control and flexible processing of samples with different evaporation endpoints.Designed for laboratories requiring both contamination control and workflow flexibility, the Teflon-Free N-EVAP provides an efficient solution for PFAS research and analytical applications.<ul><li>Small Footprint: N-EVAP Models 111 and 112 require about one square foot of bench space</li><li>Flexible: An adjustable sample holder design fits a wide variety of sample tubes and vials at once</li><li>Teflon-Free Guarantee: Made with 100% PTFE-free materials to avoid contamination of PFAS samples</li><li>Individualized Control: Optimize evaporation of diverse samples with individual gas flow control at each vial</li></ul><h3>Standard features</h3><ul><li>Nitrogen filter</li><li>Adjustable flow meter</li><li>Phthalate free silicon tubing eliminates contamination concerns</li><li>High temperature limit switch for safety</li><li>Dual band spring hoist assembly</li><li>Precision needle valve tube assembly</li><li>Needles, 4-inch x 19 gauge with chrome plated brass hub and stainless-steel shaft</li></ul><h3>Options (Add to main Cat# when purchasing)</h3><ul><li>220v wiring harness (Option Code# -2)<ul><li>12 position model: Cat# 11155-NT-2</li><li>24 position model: Cat# 11250-NT-2</li></ul></li><li>Reduced height (Option Code# -S)<ul><li>12 position model: Cat# 11155-NT-S</li><li>24 position model: Cat# 11250-NT-S</li></ul></li></ul><h3>Specifications</h3><ul><li>Bath Type: Water</li><li>Instrumental Catalog Number:&nbsp;<ul><li>Teflon-Free 12p N-EVAP: 11155-NT</li><li>Teflon-Free 24p N-EVAP: 11250-NT</li></ul></li><li>Number of Sample Positions:&nbsp;<ul><li>Teflon-Free 12p N-EVAP: 12</li><li>Teflon-Free 24p N-EVAP: 24</li></ul></li><li>Standard Dimensions (w x d x h):<ul><li>Teflon-Free 12p N-EVAP: 13 x 11 x 31 in / 33 x 28 x 79 cm</li><li>Teflon-Free 24p N-EVAP: 16 x 15 x 33 in / 41 x 38 x 61 cm</li></ul></li><li>Reduced Height Dimensions (w x d x h):<ul><li>Teflon-Free 12p N-EVAP: 13 x 11 x 24 in / 33 x 28 x 61 cm</li><li>Teflon-Free 24p N-EVAP: 16 x 15 x 24 in / 41 x 38 x 61 cm</li></ul></li><li>Sample Holder Layout: Circular</li><li>Gas Manifold Layout: Single Ring</li><li>Test Tube Range (Standard): 10-30 mm OD</li><li>Test Tube Range (Optional):&nbsp;<ul><li>Teflon-Free 12p N-EVAP: 5-16 mm OD</li><li>Teflon-Free 24p N-EVAP: 30-70 mm OD</li></ul></li><li>Gas Flow Meter:&nbsp;<ul><li>Teflon-Free 12p N-EVAP: 0-10 L/min</li><li>Teflon-Free 24p N-EVAP: 0-20 L/min</li></ul></li><li>Stainless Steel Needles (Length x Gauge):&nbsp;<ul><li>Teflon-Free 12p N-EVAP: 4.0 in x 19 ga&nbsp;</li><li>Teflon-Free 24p N-EVAP: 102 mm x 19 ga</li></ul></li><li>Sample Tray Lift Mechanism: Dual Band Spring Hoist Assembly</li><li>Standard Gas Input Range: 20-30 psig</li><li>Gas Input Range w/Optional Pressure Reducing Regulator: 30-160 psig</li></ul><h5>Heating Device Specs</h5><ul><li>Model Number:<ul><li>Teflon-Free 12p N-EVAP: 5585</li><li>Teflon-Free 24p N-EVAP: 9125</li></ul></li><li>Heating Medium: Water</li><li>Inside Dimensions (Diameter x Depth):<ul><li>Teflon-Free 12p N-EVAP: 8.5 x 4.5 in / 21.6 x 11.4 cm</li><li>Teflon-Free 24p N-EVAP: 12.0 x 4.5 in / 30.5 x 11.4 cm</li></ul></li><li>Outside Dimensions (w x d x h):<ul><li>Teflon-Free 12p N-EVAP: 13 x 11 x 7 in / 33 x 28 x 18 cm</li><li>Teflon-Free 24p N-EVAP: 16 x 15 x 7 in / 41 x 38 x 18 cm</li></ul></li><li>Total Wattage:&nbsp;<ul><li>Teflon-Free 12p N-EVAP: 550 W</li><li>Teflon-Free 24p N-EVAP: 900 W</li></ul></li><li>Bath Temperature Range: 30-90 °C</li><li>Temperature Controller Type: Mechanical Thermostat</li><li>Controller Accuracy: +/- 2 °C</li></ul><h3>Accessories</h3><ul><li>Small vessel sample holder for 12 position N-EVAP model only, for vial outside diameters of 5-16 mm (cat# NA1132)</li><li>Large vessel sample holder for 24 position N-EVAP model only, for vial outside diameters of 30-56 mm (cat# NA1113)</li><li>Teflon-free nitrogen generator (cat# NA1955-NT)</li><li>Pasteur pipette adapters (cat# NA0636)</li><li>Teflon-free pressure reducing regulator 0-160 psi (cat# NA0630-NT)</li><li>Various needle sizes and gauges</li></ul><h3>Replacement parts</h3><ul><li>P0627: Valve Tube Assembly – Post 1997</li><li>P0607: Luer &amp; washer for N-EVAP valve tube</li><li>P0634: Tube Fitting nylon 3 part for N-EVAP valve tube</li></ul>

Organomation Teflon-Free MULTIVAPs for PFAS Testing

The Teflon-Free MULTIVAP is a high-capacity evaporator for PFAS workflows, offering up to 100 sample positions, a heated water bath, and PTFE-free construction.

Teflon-free MULTIVAP nitrogen evaporators are designed for high-throughput PFAS sample preparation and concentration. Constructed entirely without PTFE or other fluoropolymers, they help minimize the risk of contamination during evaporation while enabling simultaneous processing of large sample batches.Available in 64- and 100-position configurations, these systems are suitable for laboratories using EPA Methods 533, 537.1, and 1633. A gas distribution manifold provides uniform nitrogen flow to all samples, while row-specific controls allow unused positions to be switched off to reduce nitrogen consumption.The evaporators feature a heated water bath with a temperature range of 30–100 °C and customized sample racks designed for specific tube dimensions, ensuring efficient and reproducible solvent evaporation.For laboratories requiring maximum throughput and consistent PFAS sample preparation, Teflon-free MULTIVAP evaporators provide a reliable and contamination-conscious solution.<ul><li>Capacity: Evaporate batches of up to 64 or 100 samples, with outside diameters of up to 30 mm</li><li>Precise: Digital controls allow exact temperature regulation</li><li>Teflon-Free Guarantee: Made with PTFE-free materials to avoid contamination of PFAS</li><li>Consistent: Uniform evaporation across all samples with no adjustment needed between runs</li></ul><h4>Standard features</h4><ul><li style="line-height:24px;">Adjustable flow meter</li><li style="line-height:24px;">Dual band hoist spring assembly</li><li style="line-height:24px;">High temperature limit switch for safety</li><li style="line-height:24px;">Safety control cover plate</li><li style="line-height:24px;">Digital temperature controller</li><li style="line-height:24px;">Electronic timer</li><li style="line-height:24px;">Nitrogen filter</li><li style="line-height:24px;">Gas distribution manifold</li><li style="line-height:24px;">Built-in pressure reducing regulator</li><li style="line-height:24px;">Needle guide</li></ul><h4>Options (Add to main Cat# when purchasing)</h4><ul><li>220v wiring harness (Option Code# -2)<ul><li style="vertical-align:baseline;">64 position model: Cat# 11364-NT-2</li><li style="vertical-align:baseline;">100 position model: Cat# 11300-NT-2</li></ul></li></ul><h4>Specifications</h4><ul><li>Bath Type: Water</li><li>Instrumental Catalog Number:<ul><li>Teflon-Free 64p MULTIVAP: 11364-NT</li><li>Teflon-Free 100p MULTIVAP: 11300-NT</li></ul></li><li>Number of Sample Positions:<ul><li>Teflon-Free 64p MULTIVAP: 64</li><li>Teflon-Free 100p MULTIVAP: 100</li></ul></li><li>Standard Dimensions (w x d x h): 19 x 17 x 34 in / 48 x 43 x 86 cm</li><li>Sample Holder Layout: Square</li><li>Gas Manifold Layout:<ul><li>Teflon-Free 64p MULTIVAP: 8 x 8 array</li><li>Teflon-Free 100p MULTIVAP: 10 x 10 array</li></ul></li><li>Center to Center Spacing Between Positions:<ul><li>Teflon-Free 64p MULTIVAP: 1.3125 in / 3.33 cm</li><li>Teflon-Free 100p MULTIVAP: 1.0 in / 2.54 cm</li></ul></li><li>Test Tube Diameter:<ul><li>Teflon-Free 64p MULTIVAP: 11–30 mm OD</li><li>Teflon-Free 100p MULTIVAP: 11–22 mm OD</li></ul></li><li>Gas Flow Control On/Off Valve:<ul><li>Teflon-Free 64p MULTIVAP: Every row of 8</li><li>Teflon-Free 100p MULTIVAP: Every row of 10</li></ul></li><li>Gas Flow Meter Range:<ul><li>Teflon-Free 64p MULTIVAP: 0–30 L/min</li><li>Teflon-Free 100p MULTIVAP: 0–50 L/min</li></ul></li><li>Stainless Steel Needles (Length x Gauge): 4.0 in x 19 ga / 102 mm x 19 ga</li><li>Needle Guide: Standard</li><li>Hoist Assembly: Dual Pulley &amp; Band Springs</li><li>Built-in Gas Regulator Input: 30–110 psig</li></ul><h5>Heating Device Specs</h5><ul><li>Model Number: 11196</li><li>Inside Dimensions (Diameter x Depth): 11 x 11 x 5.5 in / 28 x 28 x 14 cm</li><li>Outside Dimensions (w x d x h): 19 x 17 x 7 in / 48 x 43 x 18 cm</li><li>Total Wattage: 1100 W</li><li>Bath Temperature Range:<ul><li>Teflon-Free 64p MULTIVAP: 30–110 °C</li><li>Teflon-Free 100p MULTIVAP: 30–100 °C</li></ul></li><li>Temperature Controller Type: Digital Electronic with LED Display</li><li>Controller Accuracy: +/- 2 °C</li></ul><h4>Accessories</h4><ul><li style="line-height:24px;">Custom sized racks for 64 position model (cat# NA1360)</li><li style="line-height:24px;">Custom sized racks for 100 position model (cat# NA1361)</li><li style="line-height:24px;">Nitrogen generator (cat# NA1935)</li><li style="line-height:24px;">Pasteur pipette adapters (cat# NA0636, cannot be used with needle guide)</li><li style="line-height:24px;">Luer plugs (cat# NA1307)</li><li style="line-height:24px;">Pressure reducing regulator 0-160 psi (cat# NA0630-NT)</li><li style="line-height:24px;">Various needle sizes and gauges</li></ul>

Organomation Standard CentriVap Vacuum Concentrator

CentriVap Benchtop Vacuum Concentrators combine vacuum, centrifugal force, and heat for rapid sample concentration, processing up to 148 samples in a single run.

CentriVap Benchtop Vacuum Concentrators are designed for rapid concentration of small-volume samples. By combining centrifugal force, vacuum, and controlled heating, they provide efficient solvent evaporation for biological, microbiological, biochemical, pharmaceutical, and analytical laboratory workflows.The systems can process up to 148 samples simultaneously, accommodating volumes ranging from a few microliters to 25 mL. An optional microtiter plate rotor supports up to four standard microplates or two deep-well plates, providing additional flexibility for high-throughput applications.&nbsp;Developed in partnership with Labconco.<ul><li>Large Chamber: Holds up to 148 samples for maximum throughput</li><li>Stores 9 User-Set Programs: Temperature, heat time, and run time parameters can be saved</li><li>One Button Start Up: Start the rotor, heater, timers, and vacuum pump simultaneusly</li><li>Preheat Button: Press to turn on heater to preheat chamber prior to loading samples</li></ul><h4>Standard features</h4><ul><li>Centrifugal force, vacuum, and heat to rapidly concentrate samples</li><li>Large chamber to hold up to 148 samples</li><li>Stores 9 user-set programs such as heat or time parameters</li><li>Quick-Start one button start up for rotor, heater, timers, and vacuum pump</li><li>Preheat button to heat chamber prior to loading samples</li></ul><h4>Requirements (not included)</h4><ul><li>Vacuum pump</li><li>CentriVap cold trap</li><li>Rotor</li><li>Sample tubes</li></ul><h4> Optional accessories</h4><ul><li>CentriZap strobe light</li><li>Vacuum controller</li><li>Glass lid</li><li>CantriVap cart</li></ul><h4>Specifications</h4><ul><li>Instrument Catalog Number: LC-7810010</li><li>Number of Sample Positions: Up to 148</li><li>Dimensions (w x d x h): 14.7 x 19.3 x 11.7 in</li><li>Weight:<ul><li>Net: 42 lbs. (19 kg)</li><li>Gross: 48 lbs. (22 kg)</li></ul></li><li>Lid Material: Acrylic</li><li>Temperature Range: 0–100 °C</li><li>Warranty: 1 year</li><li>Electrical Requirements: 115V, 50/60 Hz</li><li>Rotor Speed: Up to 1725 RPM</li></ul><h4>Accessories</h4><ul><li>Metal rotors for tubes</li><li>Microliter plate rotors</li><li>Acid-resistant thermoplastic rotors</li><li>Metal rotors for pear-shaped flasks</li><li>CentriZap standard strobe light</li><li>Standard CentriVap glass lid</li></ul>

Organomation CentriVap Pro Benchtop Vacuum Concentrator

The CentriVap Pro Benchtop Vacuum Concentrator processes up to 312 samples using vacuum, centrifugal force, and heat, with advanced data logging and touchscreen control.

The CentriVap Pro Benchtop Vacuum Concentrator enables fast concentration of multiple small-volume samples using a combination of vacuum, centrifugal force, and controlled heat. Its touchscreen interface provides easy access to run settings, data logging, program management, and system diagnostics.&nbsp;With a double-stacked rotor, the system can process up to 312 samples simultaneously, covering volumes from a few microliters to 50 mL. Available as a standalone unit or as part of a complete CentriVap Concentration System.&nbsp;Developed in partnership with Labconco.<ul><li>Large Chamber: Holds up to 312 samples for maximum throughput</li><li>Stores Unlimited User-Set Programs: Temperature, heat time, pressure, and rotor speed parameters can be saved</li><li>Advanced Data Logging: View, plot, and export sample run data for analysis in CSV and PDF format</li><li>Pre-Programmed Methods: Built-in methods for processing common laboratory sample types</li></ul><h3>Standard features</h3><ul><li>Centrifugal force, vacuum, and heat to rapidly concentrate samples</li><li>Advanced data logging to view, plot, and export sample run data for analysis</li><li>Notifies user of potential rotor balance issues</li><li>Stores unlimited user-set programs for heat, time, pressure, or rotor speed parameters</li><li>Large chamber to hold up to 312 samples</li><li>Pre-programmed methods for processing common laboratory sample types</li></ul><h3>Requirements (not included)</h3><ul><li>Vacuum pump</li><li>CentriVap cold trap</li><li>Rotor(s)</li><li>Sample tubes</li></ul><h3>Options</h3><ul><li>300-watt heat boost (Cat# LC-8511200)</li><li>PTFE acid resistant coating (Cat# LC-8512100)</li><li>PTFE acid resistant coating with 300-watt heat boost (Cat# LC-8512200)</li></ul><h3>Optional accessories</h3><ul><li>CentriZap pro strobe light</li><li>CantriVap cart</li><li>Secondary trap</li></ul><h3>Specifications</h3><h4>CentriVap Pro</h4><ul><li>Instrument Catalog Number: LC-8511100</li><li>Number of Sample Positions: Up to 312</li><li>Dimensions (w x d x h): 15.0 x 19.0 x 13.9 in</li><li>Weight: Net: 52 lbs. (23.6 kg); Gross: 124 lbs. (56.2 kg)</li><li>Lid Material: Glass</li><li>Temperature Range: 0–100 °C</li><li>Warranty: 1 year</li><li>Electrical Requirements: 115V, 60 Hz</li><li>Rotor Speed: 500–1800 RPM</li></ul><h4>Acid-Resistant CentriVap Pro</h4><ul><li>Instrument Catalog Number: LC-8512100</li><li>Number of Sample Positions: Up to 312</li><li>Dimensions (w x d x h): 15.0 x 19.0 x 13.9 in</li><li>Weight: Net: 52 lbs. (23.6 kg); Gross: 124 lbs. (56.2 kg)</li><li>Lid Material: Solvent resistant glass</li><li>Temperature Range: 0–100 °C</li><li>Warranty: 1 year</li><li>Electrical Requirements: 115V, 60 Hz</li><li>Rotor Speed: 500–1800 RPM</li></ul><h3>Accessories</h3><ul><li>Microliter plate rotors&nbsp;</li><li>Metal rotors for tubes</li><li>Metal rotors for pear-shaped flasks&nbsp;</li><li>CentriZap pro strobe light</li><li>Diaphragm vacuum pumps</li><li>Rotary vane direct drive vacuum pumps</li><li>Vacuum controller</li><li>Three-way valve</li><li>Bleed valve</li><li>Vacuum tubing kit</li></ul>

Organomation Refrigerated CentriVap Pro Vacuum Concentrator

The Refrigerated CentriVap Pro Vacuum Concentrator gently concentrates up to 312 heat-sensitive samples with precise temperature control from –10 °C to +100 °C.

The Refrigerated CentriVap Pro Vacuum Concentrator is designed for efficient concentration of temperature-sensitive samples, including RNA, proteins, and other biological materials. By combining centrifugal force, vacuum, integrated refrigeration, and controlled heating, the system provides precise temperature management throughout the concentration process.The refrigeration system cools samples to –10 °C, while the built-in heater reaches temperatures up to 100 °C, enabling accurate control of operating conditions. With a double-stacked rotor configuration, the unit accommodates up to 312 samples simultaneously, handling volumes from a few microliters to 50 mL. The Refrigerated CentriVap Pro is available as a standalone instrument or as part of a complete CentriVap Concentration System.&nbsp;Developed in partnership with Labconco.<ul><li>Large Chamber: Holds up to 312 samples for maximum throughput</li><li>Stores Unlimited User-Set Programs: Temperature, heat time, pressure, and rotor speed parameters can be saved</li><li>Exclusive Temperature Range: Only concentrator that combines a refrigeration and heater system for a temp range of -10°C to 100°C</li><li>Pre-Programmed Methods: Built-in methods for processing common laboratory sample types</li></ul><h3>Standard features</h3><ul><li>Centrifugal force, vacuum, and temperature control to concentrate heat-sensitive samples</li><li>Combines a refrigeration and a heater system to reach user defined temperatures</li><li>Environmentally friendly natural gas refrigerant</li><li>Stores unlimited user-set programs for heat, time, pressure, or rotor speed parameters</li><li>Large chamber to hold up to 312 samples</li><li>Pre-programmed methods for processing common laboratory sample types</li></ul><h3>Requirements (not included)</h3><ul><li>Vacuum pump</li><li>CentriVap cold trap</li><li>Rotor(s)</li><li>Sample tubes</li></ul><h3>Options</h3><ul><li>PTFE acid resistant coating (Cat# LC-8522100)</li></ul><h3>Optional accessories</h3><ul><li>CentriZap pro strobe light</li><li>CantriVap cart</li><li>Secondary trap</li></ul><h3>Specifications</h3><h4>Refrigerated CentriVap Pro</h4><ul><li>Instrument Catalog Number: LC-8521100</li><li>Number of Sample Positions: Up to 312</li><li>Dimensions (w × d × h): 15.0 × 27.2 × 13.9 in</li><li>Weight: Net: 90 lbs. (41 kg); Gross: 164 lbs. (74 kg)</li><li>Lid Material: Glass</li><li>Temperature Range: –10 to +100 °C</li><li>Warranty: 1 year</li><li>Electrical Requirements: 115V, 60 Hz</li><li>Rotor Speed: 500–1800 RPM</li></ul><h4>Refrigerated Acid-Resistant CentriVap Pro</h4><ul><li>Instrument Catalog Number: LC-8522100</li><li>Number of Sample Positions: Up to 312</li><li>Dimensions (w × d × h): 15.0 × 27.2 × 13.9 in</li><li>Weight: Net: 90 lbs. (41 kg); Gross: 164 lbs. (74 kg)</li><li>Lid Material: Solvent resistant glass</li><li>Temperature Range: –10 to +100 °C</li><li>Warranty: 1 year</li><li>Electrical Requirements: 115V, 60 Hz</li><li>Rotor Speed: 500–1800 RPM</li></ul><h3>Accessories</h3><ul><li>Microliter plate rotors&nbsp;</li><li>Metal rotors for tubes</li><li>Metal rotors for pear-shaped flasks&nbsp;</li><li>CentriZap pro strobe light</li><li>Diaphragm vacuum pumps</li><li>Rotary vane direct drive vacuum pumps</li><li>Vacuum controller</li><li>Three-way valve</li><li>Bleed valve</li><li>Vacuum tubing kit</li></ul>

Organomation Standard CentriVap DNA Vacuum Concentrator

The CentriVap DNA Vacuum Concentrator provides rapid concentration of DNA and other low-volume samples in a compact system with integrated pump, DNA rotor, and glass traps.

The CentriVap DNA Vacuum Concentrator is a compact, ready-to-use system designed for efficient solvent removal from DNA samples and other low-volume biological specimens. The integrated package combines a vacuum concentrator, dedicated DNA rotor, diaphragm vacuum pump, dual glass traps, and all required tubing into a single benchtop solution.Optimized for processing ultra-small sample volumes, the system eliminates the need for additional accessories or system assembly, allowing laboratories to begin operation immediately after installation.Developed in partnership with Labconco.<ul><li>Large Chamber: Holds up to 148 samples for maximum throughput</li><li>Stores 9 User-Set Programs: Temperature, heat time, and run time parameters can be saved</li><li>One Button Start Up: Start the rotor, heater, timers, and vacuum pump simultaneously</li><li>Integrated Diaphragm Pump: Achieves vacuum of 7 mBar and pumping capacity of 38 L/min</li></ul><h3>Standard features</h3><ul><li>Compact design to speed evaporation of solvents from DNA samples or other small samples Stores 9 user-set programs for temperature, heat time, or run time parameters</li><li>Large chamber to hold up to 148 samples</li><li>Includes DNA rotor to hold 60 1.5mL and 72 0.5mL microcentrifuge tubes</li><li>Integrated diaphragm pump to achieve vacuum of 7 mBar and pumping capacity of 38 L/min</li><li>Quick-Start one button start up for rotor, heater, timers, and vacuum pump</li></ul><h3>Requirements (not included)</h3><ul><li>Sample tubes</li></ul><h3>Optional accessories</h3><ul><li>CentriZap pro strobe light</li><li>Rotor(s)</li><li>Vacuum controller</li><li>Glass lid</li></ul><h3>Specifications</h3><ul><li>Instrument Catalog Number: LC-7970010</li><li>Number of Sample Positions: Up to 148</li><li>Dimensions (w × d × h): 15.1 × 28.5 × 11.2 in</li><li>Weight: Net: 80 lbs. (36 kg); Gross: 100 lbs. (45 kg)</li><li>Lid Material: Acrylic</li><li>Temperature Range: 0–100 °C</li><li>Warranty: 1 year</li><li>Electrical Requirements: 115V, 60 Hz</li><li>Rotor Speed: 1725 RPM</li></ul><h3>Accessories</h3><ul><li>Microliter plate rotors</li><li>Metal rotors for tubes</li><li>Acid-resistant thermoplastic rotors</li><li>Metal rotors for pear-shaped flasks</li><li>CentriZap standard strobe light</li><li>Standard CentriVap glass lid</li></ul>

Organomation CentriVap DNA Pro Vacuum Concentrator

The CentriVap Pro DNA Vacuum Concentrator provides rapid concentration of DNA and other low-volume samples in a fully integrated system with capacity for up to 312 samples.

The CentriVap Pro DNA Vacuum Concentrator is a complete benchtop solution designed for rapid concentration of DNA samples and other ultra-low-volume specimens. The system integrates a vacuum concentrator, dedicated DNA rotor, diaphragm vacuum pump, dual glass traps, and all necessary tubing into a single ready-to-use package.Optimized for efficient solvent removal and streamlined laboratory workflows, the CentriVap Pro DNA eliminates the need for additional system components or assembly.Developed in partnership with Labconco.<ul><li>Large Chamber: Holds up to 312 samples for maximum throughput</li><li>Stores Unlimited User-Set Programs: Temperature, heat time, pressure, and rotor speed parameters can be saved</li><li>Integrated Diaphragm Pump: Achieves vacuum of 7 mBar and pumping capacity of 38 L/min</li><li>Pre-Programmed Methods: Built-in methods for processing common laboratory sample types</li></ul><h3>Standard features</h3><ul><li>All-in-one configuration designed to speed evaporation of solvents from DNA samples or other small samples Stores unlimited user-set programs for heat, time, pressure, or rotor speed parameters</li><li>Large chamber to hold up to 312 samples</li><li>Pre-programmed methods for processing common laboratory sample types</li><li>Includes DNA rotor to hold 72 1.5mL and 84 0.5mL microcentrifuge tubes</li><li>Integrated diaphragm pump to achieve vacuum of 7 mBar and pumping capacity of 38 L/min</li></ul><h3>Requirements (not included)</h3><ul><li>Sample tubes</li></ul><h3>Optional accessories</h3><ul><li>CentriZap pro strobe light</li><li>Rotor(s)</li><li>CentriVap cart</li></ul><h3>Specifications</h3><ul><li>Instrument Catalog Number: LC-8531100</li><li>Number of Sample Positions: Up to 312</li><li>Dimensions (w × d × h): 15.1 × 26.9 × 13.9 in</li><li>Weight: Net: 88 lbs. (40 kg); Gross: 162 lbs. (73.5 kg)</li><li>Lid Material: Glass</li><li>Temperature Range: 0–100 °C</li><li>Warranty: 1 year</li><li>Electrical Requirements: 115V, 60 Hz</li><li>Rotor Speed: 500-1800 RPM</li></ul><h3>Accessories</h3><ul><li>Microliter plate rotors</li><li>Metal rotors for tubes&nbsp;</li><li>Metal rotors for pear-shaped flasks&nbsp;</li><li>CentriZap pro strobe light</li><li>Diaphragm vacuum pumps</li><li>Rotary vane direct drive vacuum pumps</li><li>Vacuum controller</li><li>Three-way valve</li><li>Bleed valve</li><li>Vacuum tubing kit</li></ul>

Organomation CentriVap Cold Traps

CentriVap Cold Traps capture evaporated solvents and protect vacuum pumps from moisture and corrosive vapors. Available with collector temperatures of –50 °C, –84 °C, or –105 °C.

The CentriVap Cold Traps are designed to efficiently capture evaporated solvents from CentriVap Vacuum Concentrators, helping protect both the vacuum pump and laboratory environment from vapors, fumes, and corrosive compounds.&nbsp;In addition to concentration workflows, they are suitable for applications such as freeze-drying and desiccation. Models are available with collector temperatures of –50 °C, –84 °C, or –105 °C and can be purchased either as standalone units or as part of complete CentriVap Concentration Systems.Developed in partnership with Labconco.<ul><li>Eco-Cool Refrigerant: Environmentally friendly natural gas refrigerant</li><li>Temperature Graph: Displays relative coil temperature and has green-light indicator</li><li>Corrosion-Resistant: Corrosion-resistant polypropylene valve and stainless steel plumbing</li></ul><h3>Standard features</h3><ul><li>Meant to protect the vacuum pump by trapping moisture vapors and corrosive fumes</li><li>Collector temperatures of -50°C, -84°C, and -105°C available</li><li>Temperature graph displays relative collector coil temperature</li><li>Stainless steel collector holds up to four liters of liquid</li><li>Corrosion-resistant collector drain&nbsp;</li></ul><h3>Options</h3><ul><li>-50°C with acrylic lid (Cat# LC-8601000)</li><li>-50°C with stainless lid (Cat# LC-8601100)</li><li>-84°C with stainless lid (Cat# LC-8611100)</li><li>-105°C with stainless lid (Cat# LC-8621100)</li></ul><h3>Optional accessories</h3><ul><li>Clear canisters and chemical trap inserts</li><li>Glass trap</li><li>Manifold</li><li>CentriVap cart</li></ul><h3>Specifications</h3><h4>CentriVap Cold Trap –50 °C</h4><ul><li>Instrument Catalog Number: LC-8601000</li><li>Collector Size: 4 liters</li><li>Dimensions (w × d × h): 14.5 × 24.2 × 13.8 in</li><li>Weight: Net: 70 lbs. (32 kg); Gross: 80 lbs. (36 kg)</li><li>Lid Material: Acrylic or stainless</li><li>Collector Coil Temperature: –40 °C</li><li>Cold Trap Temperature: –50 °C</li><li>Warranty: 1 year</li><li>Electrical Requirements: 115V, 60 Hz</li></ul><h4>CentriVap Cold Trap –84 °C</h4><ul><li>Instrument Catalog Number: LC-8611100</li><li>Collector Size: 4 liters</li><li>Dimensions (w × d × h): 14.5 × 22.0 × 20.9 in</li><li>Weight: Net: 135 lbs. (61 kg); Gross: 142 lbs. (64 kg)</li><li>Lid Material: Stainless</li><li>Collector Coil Temperature: –65 °C</li><li>Cold Trap Temperature: –84 °C</li><li>Warranty: 1 year</li><li>Electrical Requirements: 115V, 60 Hz</li></ul><h4>CentriVap Cold Trap –84 °C</h4><ul><li>Instrument Catalog Number: LC-8611100</li><li>Collector Size: 4 liters</li><li>Dimensions (w × d × h): 14.5 × 22.0 × 20.9 in</li><li>Weight: Net: 135 lbs. (61 kg); Gross: 142 lbs. (64 kg)</li><li>Lid Material: Stainless</li><li>Collector Coil Temperature: –65 °C</li><li>Cold Trap Temperature: –84 °C</li><li>Warranty: 1 year</li><li>Electrical Requirements: 115V, 60 Hz</li></ul><h3>Accessories</h3><ul><li>Chemical trap</li><li>Trap inserts</li><li>Glass trap</li><li>Stainless steel lid (optional for -50°C model)</li><li>Two-port manifold</li></ul>

Organomation Dual Microplate Evaporator with Digital Timer

The Dual Microplate Evaporator with Digital Timer enables simultaneous processing of two 96-well plates with precise temperature control, programmable timing, and semi-attended operation.

The Dual Microplate Evaporator with Digital Timer is designed for efficient evaporation of samples in two 96-well microplates simultaneously. Based on the proven MULTIVAP dry block platform, the system combines precise temperature control, an integrated digital timer, and a built-in gas pressure gauge to provide reliable and reproducible evaporation performance.A height-adjustable manifold allows convenient starting and stopping of evaporation for both plates at the same time, while spring-assisted lifting ensures smooth and effortless operation. The programmable timer enables semi-attended operation by automatically stopping heat and gas flow when the preset evaporation time has elapsed.<h3>Specifications</h3><h4>Dual Microplate Evaporator with Digital Timer</h4><ul style="list-style-type:disc;"><li>Instrumental Catalog Number: 11802</li><li>Number of Sample Plates: 2</li><li>Overall Dimension (w × d × h): 16 × 14 × 22 in; 41 × 36 × 56 cm</li><li>Gas Manifold Layout: Dual 8 × 12 array</li><li>Microplate Dimensions (w × d): 3.375 × 5.0 in; 8.5 × 13 cm</li><li>Stainless Steel Needles (Length × Gauge): 2.0 in × 19 ga; 51 mm × 19 ga</li><li>Hoist Assembly: Spring-assisted</li><li>Integrated Control Box with Timer for Nitrogen &amp; Heat: Standard</li><li>Built-in Gas Regulator Input: 50–110 psig</li><li>Acid Resistant Coating (Option Code –RT): Optional</li></ul><h4>Heating Device Specs</h4><ul><li>Bath Model Number: 9156</li><li>Heating Medium: Aluminum dry block</li><li>Outside Dimensions (w × d × h): 16 × 14 × 6.5 in; 41 × 36 × 15 cm</li><li>Total Wattage: 900 W</li><li>Bath Temperature Range: 30–120 °C</li><li>Temperature Controller Type: Digital Electronic with LED Display</li><li>Controller Accuracy: ±2 °C</li></ul>

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