Ask any analytical chemist which hyphenated technique has become indispensable over the past decade, and the answer will almost certainly be the same: tandem chromatography–mass spectrometry. Whether it is <a target="_blank" rel="noopener noreferrer" href="https://www.organomation.com/preparing-samples-for-lc-ms/ms-analysis">LC–MS/MS</a> quantifying a novel biologic’s metabolic fate, or <a target="_blank" rel="noopener noreferrer" href="https://www.organomation.com/preparing-samples-for-gc-ms/ms-analysis">GC–MS/MS</a> chasing per- and polyfluoroalkyl substances (PFAS) down to sub-part-per-trillion levels in municipal water, the combination of chromatographic separation with the specificity of tandem mass detection has become the analytical workhorse of choice across virtually every regulated sector.Below we examine the key forces propelling this expansion, from biopharma pipeline dynamics and PFAS regulatory mandates to AI-driven automation and reshoring of pharmaceutical manufacturing—and explore what each trend means for laboratories managing sample preparation and analytical workflows.<h3>Biopharma: The Engine Room of LC–MS/MS Demand</h3><h4>GLP-1 Agonists and the Metabolomics Gold Rush</h4>The explosive commercial and scientific interest in GLP-1 receptor agonists—<a target="_blank" rel="noopener noreferrer" href="https://www.sepscience.com/advancing-glp-1-peptide-analysis-chromatography-challenges-and-innovations-12163">semaglutide and related peptide therapeutics </a>for diabetes and obesity—has dramatically expanded the analytical demands placed on tandem MS platforms. Discovery programs require precise quantification of peptide drug candidates and endogenous biomarkers across complex biological matrices. These workflows rely on high-sensitivity LC–MS/MS for pharmacokinetic profiling, receptor occupancy studies, and metabolomics characterization. Metabolomics is, in fact, projected to be the fastest-growing application segment in mass spectrometry, driven in part by its growing role in cancer screening, biomarker discovery, and metabolic disease research.I have been spending more time learning about GLP-1s because this is the hot topic that people want to discuss on the Concentrating on <a target="_blank" rel="noopener noreferrer" href="https://open.spotify.com/show/1wZg67rCjoGju4yhqxI3tL?si=n9GLz9zjSCOrVfXPxFPhng&amp;nd=1&amp;dlsi=52868e027aad4d22">Chromatography podcast</a>. With that said, I was astounded looking at CNBC.com during breakfast this morning to see that <a target="_blank" rel="noopener noreferrer" href="https://www.cnbc.com/2026/03/21/glp-1-diets-restaurants-protein-fiber-weight-loss-drugs.html">one in eight Americans are currently taking one of these drugs such as Ozempic</a>.<h4>Antibody–Drug Conjugates and Gene Therapy: Complexity at Every Step</h4>The ascent of antibody–drug conjugates (ADCs) and gene therapies has introduced a new level of analytical complexity. ADCs blend the target specificity of monoclonal antibodies with the cytotoxic potency of small-molecule payloads—and characterizing the linker chemistry, drug-to-antibody ratio (DAR), and conjugate stability demands high-resolution LC–MS/MS at every stage from discovery through QC release testing. Gene therapy vectors require equally rigorous characterization of impurities, aggregates, and empty/full capsid ratios.This translates into a direct need for low-evaporation, high-recovery concentration methods that preserve labile protein structures and maintain sample integrity prior to LC–MS/MS injection. <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/article/5392">Nitrogen evaporation workflows</a> that minimize oxidative stress and maintain sample temperature are increasingly critical in these pipelines.<h4>Precision Medicine and Multi-Omics Integration</h4>The shift toward precision medicine has accelerated adoption of high-throughput, multi-analyte MS platforms. Proteomics, metabolomics, and lipidomics workflows are converging on a single analytical platform—tandem MS—and generating datasets of a scale and complexity that were unimaginable ten years ago.Make no mistake: the triple quadrupole serves an irreplaceable role in quantitative targeted analysis. At the same time, <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products?category=134&amp;manufacturerItems=3">Orbitrap </a>and Q–TOF hybrid platforms are growing rapidly as researchers demand full-scan accurate mass for untargeted discovery.<h3>Environmental Mandates: PFAS Testing Drives Adoption</h3>Environmental testing is something that every person, chemist or not, can understand the importance of. Mounting mandates from the U.S. Environmental Protection Agency and European regulators regarding PFAS—the “forever chemicals” whose extraordinary environmental persistence is matched only by the analytical challenge of detecting them at trace levels—have created immediate, compliance-driven investment in LC–MS/MS infrastructure.<h4>The Regulatory Framework Chemists Need to Know</h4>The EPA has codified a suite of LC–MS/MS-based methods as the analytical standard for PFAS in water and solid matrices:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://blog.organomation.com/blog/epa-533-drying-down-pfas-samples-after-spe">EPA Method 533</a>: Weak anion exchange SPE combined with LC–MS/MS; covers 25 PFAS including short-chain compounds in drinking water.</li><li><a target="_blank" rel="noopener noreferrer" href="https://blog.organomation.com/blog/sample-concentration-epa-method-537-pfas-determination">EPA Method 537.1</a>: Reversed-phase SPE followed by LC–MS/MS; covers 18 PFAS including the GenX compound, with method detection limits in the low ng/L range.</li><li><a target="_blank" rel="noopener noreferrer" href="https://www.agilent.com/en/solutions/environmental/water-testing/pfas-in-water/us-epa-method-8327?srsltid=AfmBOooCY1pcavj7B1PH-75d3HO4BGDglNlhmyTyrpDY3zvUksMO1dlg">EPA Method 8327</a>: LC–MS/MS for selected PFAS in prepared extracts of aqueous and solid matrices.</li><li><a target="_blank" rel="noopener noreferrer" href="https://blog.organomation.com/blog/preparing-diverse-sample-matrices-for-epa-method-1633">EPA Draft Method 1633</a>: The emerging benchmark for PFAS in non-aqueous matrices—aqueous, solid, biosolids, and tissue—quantifying up to 40 PFAS.</li></ul>All of these methods designate LC–MS/MS, specifically LC coupled to triple quadrupole or tandem-in-time platforms operating in negative electrospray ionization mode with multiple reaction monitoring (MRM), as the required or recommended analytical technique. PFAS analysis is, at its core, an LC–MS/MS problem.<h4>The Sample Preparation Bottleneck</h4>Chemists who have worked with PFAS methods understand the particular demands they place on sample preparation. The ubiquity of<a target="_blank" rel="noopener noreferrer" href="https://blog.organomation.com/blog/tackling-pfas-contamination-practical-insights-from-epa-537.1-method-development"> PFAS in laboratory materials</a>—PTFE tubing, some SPE sorbents, standard bench supplies—means that blank contamination control is as analytically demanding as the detection itself. EPA 537.1 requires that sample volumes of approximately 250 mL be extracted and reconstituted in as little as 1 mL, creating a 250:1 concentration factor that can expose even trace contamination in the sample processing chain. The installation of a delay column between the LC pump and autosampler to prevent instrument background interference is now standard practice.This is precisely where robust, <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/article/5385">inert nitrogen evaporation </a>systems earn their keep. PFAS workflows that use nitrogen-assisted evaporation to concentrate extracts prior to reconstitution benefit from materials that avoid PTFE and other fluoropolymers that can leach PFAS background—a consideration Organomation addresses in its concentration system designs.The analytical community is also moving beyond targeted PFAS analysis. High-resolution accurate mass (HRAM) spectrometry via Orbitrap technology, paired with non-targeted screening workflows, is gaining traction for the identification of the more than 5,000 currently catalogued PFAS compounds and the novel structures that continue to emerge. LC–MS/MS remains the quantitative gold standard; HRAM provides the discovery layer.<h3>Technological Trends Reshaping the LC–MS/MS Workflow</h3><h4>Artificial Intelligence and Automated Data Interpretation</h4>The datasets generated by modern tandem MS platforms—particularly in omics applications—are too large and too complex for conventional manual review. AI-driven spectral deconvolution, automated peak integration, and AI-assisted hypothesis generation are now embedded in the software suites accompanying leading instruments. <a target="_blank" rel="noopener noreferrer" href="https://www.agilent.com/about/newsroom/presrel/2022/17feb-gp22004.html?srsltid=AfmBOop3warRIaEojXM2YyMML6RXfMIDzE-Wm0h-SiKkkocBeeET2m7u">Agilent’s acquisition of Virtual Control’s ACIES </a>software specifically to automate LC–MS and GC–MS data analysis is emblematic of this direction.For laboratory managers, AI integration means smaller specialized teams can operate high-throughput multi-analyte workflows—but it also means that the front-end sample preparation must be even more reproducible, since algorithmic interpretation amplifies inconsistencies introduced upstream.<h4>Online SPE Coupling and “Chromatography Without Walls”</h4>A significant trend is the integration of solid-phase extraction directly into the HPLC flow path—so-called online SPE–HPLC coupling. Systems that combine extraction and chromatographic separation in a single analytical instrument reduce manual transfer steps, minimize the risk of sample loss or contamination, and dramatically increase throughput. For analytes at very low concentrations, online SPE provides the on-column concentration capability that traditional offline preparation achieves with manual evaporation steps.That said, offline sample preparation—including <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/article/5392">nitrogen-assisted evaporation</a> under controlled conditions, <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/2407">liquid–liquid extraction</a>, and protein precipitation—retains significant advantages in flexibility, matrix handling, and the ability to process sample volumes that exceed online system capacity. The two approaches are increasingly complementary rather than competitive in well-designed analytical laboratories.<h4>High-Purity Solvents and Reference Materials</h4>As detection limits push further into the femtogram range and regulatory methods demand demonstrable blank performance, the quality of analytical consumables—mobile phase solvents, derivatization reagents, reference standards—has moved from background consideration to front-of-mind. Method validation in regulated environments now routinely requires vendor certification of solvent purity at a level that directly interfaces with instrument performance.<h3>The Ever-Present Need for Sample Evaporation</h3>As LC–MS/MS methods push detection limits lower, the analytical burden shifts increasingly upstream. The quality of the concentration, cleanup, and reconstitution steps preceding injection determines whether the instrument’s theoretical sensitivity is achievable in practice.Several specific developments are particularly relevant:<ul><li>ADC and gene therapy characterization workflows require gentle, low-temperature evaporation that preserves protein structure and prevents aggregation prior to LC–MS/MS. Nitrogen evaporation under controlled conditions is the preferred approach.</li><li>PFAS trace analysis demands evaporation systems constructed from PFAS-inert materials, with rigorous attention to avoiding fluoropolymer surfaces throughout the sample path.</li><li>High-throughput pharmaceutical QC driven by reshoring demands parallel processing capability—multi-position evaporators that maintain consistent flow and temperature across all positions simultaneously.</li><li>Multi-omics and metabolomics workflows generate large sample batches that benefit from automated, walk-away evaporation with programmable endpoints to ensure reproducible final volumes across a cohort.</li></ul>Tandem chromatography–mass spectrometry is not merely growing; it is becoming structurally embedded in the analytical workflows of every major regulated industry. The convergence of biopharma complexity, PFAS regulatory mandates, AI-enabled data analysis, and pharmaceutical reshoring is creating a multi-year demand cycle that will require laboratories to invest not only in instruments, but in the entire sample preparation ecosystem that makes those instruments perform.For analytical chemists, the practical takeaway is this: as mass spectrometry sensitivity continues to advance, the sample preparation step becomes the binding constraint on method performance. Whether you are developing a new PFAS method to meet EPA 1633, characterizing an ADC’s drug-to-antibody ratio, or running a 500-sample metabolomics cohort overnight, the reliability and cleanliness of your concentration and cleanup workflow determines the quality of every data point that follows.&nbsp;

The Continued Rise of Tandem Chromatography–Mass Spectrometry

News from LabRulezLCMS Library - Week 27, 2026

🎤Dr. Christopher Reid (Professor of Chemistry and Biochemistry at Bryant University in Rhode Island)In this episode of Concentrating on Chromatography, host Dave Oliva sits down with Chris Reid to explore how chemical biology and LC-MS are being used to tackle one of the most urgent global challenges: antimicrobial resistance.As antibiotic resistance continues to rise—and new drug development struggles to keep pace—researchers are looking beyond traditional approaches. Instead of targeting how bacteria build their cell walls, Chris’s work focuses on how they break them down, opening the door to entirely new antimicrobial strategies.<h4>What You’ll Learn in This Episode:</h4><ul><li>Why antimicrobial resistance is accelerating globally</li><li>What peptidoglycan is and why it’s essential to bacterial survival</li><li>How targeting cell wall degradation differs from traditional antibiotics</li><li>The strategy behind designing small molecule probes and inhibitors</li><li>How LC-MS is used to analyze peptidoglycan fragments and enzyme activity</li><li>Key analytical challenges: complex mixtures, low-abundance species, and structural similarity</li><li>The importance of sample preparation and reproducibility in LC-MS workflows</li><li>How this research could lead to new antibiotic targets</li></ul><h3>Video Transcription</h3><h4>The Growing Challenge of Antibiotic Resistance</h4>According to Reid, antibiotic resistance is increasing across a broad spectrum of bacterial pathogens that were once readily treated with existing therapies. In some cases, clinicians must now rely on only a handful of last-line antibiotics, while resistance is also rising in diseases such as tuberculosis.One of the major obstacles is the limited commercial incentive to develop entirely new antibiotics. Because bacterial resistance can emerge relatively quickly after a drug reaches the market, pharmaceutical companies often favor modifying existing antibiotics or combining them with resistance-modifying agents rather than investing in completely new drug classes. As a result, genuinely novel antibacterial targets remain urgently needed.<h4>Why the Bacterial Cell Wall Remains an Attractive Target</h4>The bacterial cell wall consists primarily of peptidoglycan, a highly cross-linked polymer that provides structural integrity, maintains cell shape, and enables bacterial growth and division.Many widely used antibiotics—including the β-lactam antibiotics such as penicillins—target enzymes responsible for synthesizing or cross-linking peptidoglycan. These pathways have proven highly successful therapeutic targets because peptidoglycan is unique to bacteria and absent from human cells, minimizing unwanted effects on the host.However, most existing antibiotics target only specific stages of peptidoglycan biosynthesis. Reid's research explores another part of this complex pathway: enzymes responsible for degrading the carbohydrate backbone of peptidoglycan during normal bacterial growth and remodeling. These enzymes may represent an underexplored class of antimicrobial targets capable of overcoming existing resistance mechanisms.<h4>Targeting the Glycan Backbone</h4>A key advantage of focusing on the carbohydrate backbone is its remarkable conservation across both Gram-positive and Gram-negative bacteria.Whereas the peptide components of peptidoglycan vary considerably between bacterial species—and frequently acquire mutations associated with antibiotic resistance—the glycan backbone remains highly conserved and tolerates relatively few structural modifications.This biological constraint makes enzymes acting on the glycan backbone particularly attractive targets. Reid's group developed a series of small-molecule probes and inhibitors designed to recognize enzymes known as N-acetylglucosaminidases, which cleave glycosidic bonds within peptidoglycan and generate soluble degradation products.Rather than beginning with purified enzymes, the researchers adopted a top-down phenotypic screening strategy. Candidate compounds were first evaluated for their ability to inhibit bacterial growth before progressively narrowing the list of potential molecular targets through genetic studies, microscopy, enzyme assays, and biochemical characterization. This iterative workflow ultimately identified compounds capable of inhibiting the desired enzyme class while simultaneously providing valuable chemical probes for studying bacterial cell wall biology.<h4>LC-MS as a Central Analytical Tool</h4>Liquid chromatography coupled with mass spectrometry plays a central role throughout the project by enabling detailed characterization of structural changes occurring within peptidoglycan after bacterial cells are treated with candidate inhibitors.Because intact peptidoglycan is an insoluble polymer, sample preparation begins with isolation of the bacterial cell wall through detergent extraction and differential centrifugation. Additional purification steps remove proteins, nucleic acids, and teichoic acids before enzymatic digestion converts the insoluble material into soluble fragments suitable for chromatographic analysis.The resulting digest is analyzed by LC-MS to examine changes in the distribution of peptidoglycan fragments. Chromatographic retention times provide an immediate indication of changes in cross-linking, with larger oligomers such as trimers and tetramers generally eluting later than monomeric fragments. Mass spectrometry then confirms the identity of these fragments by measuring their intact molecular masses, while tandem MS experiments can provide further structural information when required.<h4>Sample Preparation Determines Data Quality</h4>Reid emphasized that sample preparation represents one of the most critical—and challenging—stages of the entire workflow.Because peptidoglycan analysis involves multiple purification, digestion, and reduction steps, even minor procedural differences between samples can introduce analytical artifacts that complicate biological interpretation.Maintaining strict consistency throughout sample preparation is therefore essential. Appropriate controls must accompany every experiment, ensuring that observed chromatographic and mass spectrometric differences truly reflect biological responses rather than experimental variability. The complexity of bacterial cell wall composition further increases the analytical challenge, as subtle differences in amino acid substitutions and low-abundance cross-linked species can complicate LC-MS data interpretation.<h4>Chemical Biology for Future Antibiotic Discovery</h4>Although the identified compounds may eventually serve as starting points for antibiotic development, Reid views them primarily as chemical biology tools.By selectively inhibiting individual enzymes, these probes allow researchers to investigate previously unexplored aspects of bacterial cell wall remodeling that cannot easily be studied using classical genetic approaches alone.The research team is now expanding this strategy by combining their probes with proximity-labeling proteomics and mass spectrometry, aiming to map protein interaction networks associated with bacterial cell wall degradation. Such studies may reveal entirely new antibacterial targets and provide deeper insight into the biological processes governing bacterial growth and division.Ultimately, the work illustrates how integrating synthetic chemistry, microbiology, molecular biology, and advanced LC-MS can accelerate the search for innovative therapeutic strategies against antimicrobial resistance. As existing antibiotics become progressively less effective, multidisciplinary approaches such as these may play an increasingly important role in identifying the next generation of antibacterial targets.<blockquote>This text has been automatically transcribed from a video presentation using AI technology. It may contain inaccuracies and is not guaranteed to be 100% correct.</blockquote><blockquote><h4>Concentrating on Chromatography Podcast</h4>Dive into the frontiers of chromatography, mass spectrometry, and sample preparation with host David Oliva. Each episode features candid conversations with leading researchers, industry innovators, and passionate scientists who are shaping the future of analytical chemistry. From decoding PFAS detection challenges to exploring the latest in AI-assisted liquid chromatography, this show uncovers practical workflows, sustainability breakthroughs, and the real-world impact of separation science. Whether you’re a chromatographer, lab professional, or researcher you'll discover inspiring content!You can find Concentrating on Chromatography Podcast in podcast apps:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://open.spotify.com/show/1wZg67rCjoGju4yhqxI3tL">Spotify</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podcasts.apple.com/tz/podcast/concentrating-on-chromatography/id1788429185">Apple podcast</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podscan.fm/podcasts/concentrating-on-chromatography">podscan</a></li></ul>and on <a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/@ChromatographyTalk/videos">YouTube channel</a></blockquote>

 Fighting Antibiotic Resistance with LC-MS: Targeting Bacterial Cell Walls

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Organomation, founded in 1959, designs and manufactures high-quality nitrogen evaporators and extraction systems. Known for innovation and durability, their lab instruments are used globally for efficient sample preparation with strong customer support.

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Thermo Scientific Dionex IonPac CS19-4μm IC Columns

High-capacity ion-exchange column with 4 μm resin for highest resolution of cations and polar amines in complex samples. Enables fast, reliable separations and cost-effective operation with HPIC systems.

Attain the optimal combination of chromatographic speed and high resolution using the new Thermo Scientific™ Dionex™ IonPac™ CS19-4μm Capillary, Analytical, &amp; Guard Column. This high-capacity, high-resolution carboxylate-functionalized column provides excellent resolution of common cations, small polar amines, and polyvalent amines in complex sample matrices such as power plant waters treated with ammonium, morpholine, or ethanolamine, chemical additives, chemical process solutions, scrubber solutions, personal care products, and food samples. Compared to the Thermo Scientific™ Dionex™ IonPac™ CS19 column, this column uses smaller resin particles for more efficient separations resulting in more accurate peak integration and more reliable results.<h5>Highest Resolution Separation of Common Cations and Small Polar Amines in Diverse Matrices</h5><ul><li>Highest resolution, through the use of smaller resin particles, of common cations and small polar amines in complex sample matrices</li><li>Higher peak efficiency and increased peak resolution for more consistent integration and more reliable results</li><li>Easily transfer applications from the Dionex IonPac CS19 column to the 4 μm column due to the similar selectivity</li><li>Simple gradient separation of small polar amines (including alkanolamines and methylamines), and moderately hydrophobic and polyvalent amines (including biogenic amines and alkyl diamines)</li><li>High capacity facilitates injection of more concentrated samples without column overloading or peak broadening</li><li>Compatible with moderate amounts of organic solvents, excluding alcohols, to enhance analyte solubility, modify column selectivity, and facilitate effective column clean-up</li></ul><h5>Use With a High-Pressure IC System</h5>Higher resolution is achieved through the use of smaller resin particles, which produce a column backpressure over 3000 psi at the standard flow rates. A high-pressure IC system, such as the Thermo Scientific™ Dionex™ ICS-5000+ HPIC™ or the Dionex ICS-4000 Capillary HPIC system is required to operate this column under standard conditions and take advantage of elevated flow rates and faster run times.<h5>Reduce Operating Costs With Lower Eluent Requirements</h5>The Dionex IonPac CS19-4μm capillary column provides the same performance as the standard bore and microbore Dionex IonPac CS19-4μm columns because it is packed with the same material. Operating costs are reduced because the capillary system operates at only 1% of the eluent flow rate of the standard bore system, requiring less eluent and producing less waste.<h5>Multiple Formats Available for Application Flexibility</h5><ul><li>4x250mm, 2x250mm analytical columns</li><li>4x50mm, 2x50mm guard columns</li><li>0.4x250mm capillary column, 0.4x50mm capillary guard column</li><li>Longer 250mm columns facilitate higher resolution separations of more complex sample matrices</li><li>Smaller i.d. columns provide higher mass sensitivity, eluent and reagent conservation and lower operating costs</li></ul><h4>Specifications</h4><ul><li>Crosslinking: 55% DVB</li><li>Column Capacity: 2410 μeq</li><li>For Use With (Application): Cation Exchange</li><li>Max. Pressure: 5000 psi (345 bar)</li><li>Solvent Compatibility: Acidic Eluents (pH 0 to 7), 10% HPLC Solvents, Alcohols Should be Avoided</li><li>Stationary phase: IonPac CS19-4μm</li><li>Format: Standard Bore</li></ul>

Thermo Scientific Dionex IonPac CS20 IC Columns

Analyze inorganic cations and amines using the Thermo Scientific™ Dionex™ IonPac™ CS20 ion chromatography (IC) columns.

Analyze inorganic cations and amines using the Thermo Scientific™ Dionex™ IonPac™ CS20 ion chromatography (IC) columns. Designed to complement Dionex IonPac CS18 and Dionex IonPac CS19 columns, the Dionex IonPac CS20 columns provide a large separation window between monovalent and divalent cations. This allows most amines to elute after the alkali metals but before the alkaline earth metals, moving the amines away from matrix ions that would normally make quantitation difficult. Its selectivity makes the Dionex IonPac CS20 particularly useful for determining a variety of alkyl and alkanol amines.<h5>Superior performance in the separation of common inorganic cations and amines</h5><ul><li>Use the high capacity Dionex IonPac CS20 to determine inorganic cations and amines including methylamines, ethylamines, ethanolamines, and alkanolamines in diverse sample matrices</li><li>Unique stationary phase functionalized with a combination of sulfonic, phosphonic, and carboxylic acid groups can tolerate acidic samples containing up to 100mM hydronium ion (pH 1) with minimum loss of performance</li><li>Operable over a wide temperature range (15-70°C) to facilitate method development and improve critical pair separations</li><li>Compatible with 100% organic solvents (acetonitrile and acetone) to enhance analyte solubility, modify column selectivity, and facilitate effective column clean-up</li></ul><h5>Use with a high-pressure IC system</h5>A high-pressure IC system, such as the Thermo Scientific™ Dionex™ ICS-5000+ HPIC™, Dionex Integrion™ HPIC system, or the Dionex ICS-4000 Capillary HPIC system is required to operate this column under standard conditions.<h5>Reduce operating costs with lower eluent requirements</h5>The Dionex IonPac CS20 capillary columns provide the same performance as the standard bore and microbore Dionex IonPac CS20 columns because they are packed with the same material. Operating costs are reduced because the capillary system operates at only 1% of the eluent flow rate of the standard bore system, requiring less eluent and producing less waste.<h5>Multiple Formats Available</h5><ul><li>4x250mm and 2x250mm analytical columns</li><li>4x50mm and 2x50mm analytical guard columns</li><li>0.4x250mm capillary columns</li><li>0.4x50mm capillary guard columns</li><li>Smaller i.d. columns provide higher mass sensitivity, conserve eluent and reagents, and reduce operating costs</li></ul><h4>Specifications</h4><ul><li>Crosslinking: 55% DVB</li><li>Column Capacity: 3000 μeq</li><li>For Use With (Application): Cation Exchange</li><li>Max. Pressure: 5000 psi (345 bar)</li><li>Solvent Compatibility: pH 0 to 7, 0 to 100% Organic HPLC Solvents, Alcohols Should be Avoided</li><li>Stationary phase: Macroporous Resin</li><li>Format: Standard Bore</li><li>Packing Material: Ethylvinylbenzene/Divinylbenzene</li></ul>

Thermo Scientific Dionex IonPac CS21-Fast-4μm IC Columns

Resolve quaternary amine cationic polar pesticides including chlormequat, mepiquat, paraquat, and diquat with the Thermo Scientific™ Dionex™ IonPac™ CS21-Fast-4μm column. 

Resolve quaternary amine cationic polar pesticides including chlormequat, mepiquat, paraquat, and diquat with the Thermo Scientific™ Dionex™ IonPac™ CS21-Fast-4μm column. The unique selectivity of the Dionex IonPac CS21-Fast-4μm column allows it to resolve trace amounts of cationic polar pesticides in high ionic strength matrices within approximately fifteen minutes using an electrolytically generated MSA gradient. Quaternary amines are eluted away from matrix cations, making the Dionex IonPac CS21-Fast-4μm column ideal for IC-MS/MS applications where matrix ions are diverted to waste.<h5>Superior Chromatographic Performance</h5><ul><li>High capacity allows injection of complex matrices without overloading the column while maintaining excellent peak shapes for lower concentration analytes.</li><li>Quickly separate trace levels of the four major quaternary amine cationic polar pesticides chlormequat, mepiquat, paraquat, and diquat in high ionic strength matrices using an MSA gradient.</li><li>Separate other cationic pesticides of interest including diethanolamine, triethanolamine, N-N-dimethylhydrazine, trimethylsulfonium, morpholine, melamine, streptomycin, and nereistoxin.</li></ul><h5>Specifically designed for IC-MS/MS applications</h5><ul><li>Completely resolves paraquat and diquat, species with similar masses.</li><li>Available in microbore format that is compatible with MS flow rates.</li><li>Selectivity allows matrix ions to be diverted to waste which keeps the MS source cleaner.</li><li>Solvent compatible (up to 100% acetonitrile and 20% isopropyl alcohol).</li><li>Fast analysis of cationic polar pesticides in food, beverages, and environmental waters.</li></ul><h5>Use with a High-Pressure IC system</h5>A high-pressure IC system, such as the <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/410">Thermo Scientific™ Dionex™ ICS-6000 HPIC system</a> or <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/408">Thermo Scientific™ Dionex™ Integrion™ HPIC system</a> is required to operate this column under standard conditions.<h4>Specifications</h4><ul><li>Crosslinking: 80% DVB</li><li>Column Capacity: 110 μeq</li><li>For Use With (Application): Cation Exchange</li><li>Max. Pressure: 5000 psi (345 bar)</li><li>Solvent Compatibility: pH 0-7, HPLC solvents (100% acetonitrile and up to 20% isopropyl alcohol), primary and secondary alcohols should be avoided)</li><li>Format: Microbore</li><li>Packing Material: Ethylvinylbenzene/Divinylbenzene</li></ul>

Thermo Scientific SurePac Bio 550 SEC MDi HPLC Columns

SurePac™ Bio 550 SEC MDi™ column delivers high-resolution, reproducible AAV size-based separations with 3 μm silica, 550 Å pores, and bioinert hardware for optimal recovery and QC reliability.

Experience the future of Size-Exclusion Chromatography (SEC) with SurePac™ Bio 550 SEC MDi™ analytical columns and guards exclusively designed to deliver robust and reproducible performance at high resolution and throughput to accelerate your therapeutics analysis process. The column's groundbreaking MDi™ technology integrates our advanced 3 μm monodisperse silica particle platform with bioinert hardware to ensure superior reliability for best sample recovery. SurePac™ Bio 550 SEC MDi™ column is ideal for AAV gene therapeutics analysis and offers excellent selectivity due to the dedicated smaller particle (3 μm) size combined with wide-pore (550Å) for separating monomeric AAVs from aggregates based on their size differences.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Sure_Pac_Bio_550_SEC_M_Di_HPLC_Columns_3_8391a584e0.jpg" alt="Thermo Scientific: SEM image of 3μm monodisperse silica particles (left) vs. 3 μm polydisperse particles (right)" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Sure_Pac_Bio_550_SEC_M_Di_HPLC_Columns_3_8391a584e0.jpg 245w," sizes="100vw" width="1023" height="508">SurePac Bio 550 SEC MDi columns and guards are based on high-purity, spherical, porous (550 Å), 3 μm monodispersed silica particles that are covalently modified with a proprietary diol hydrophilic layer. This unique design yields shorter diffusion distances and enhanced reproducible mass transfer and narrower peaks. The consistent size of these particles facilitates precise control over media synthesis and column packing, significantly improving column-to-column and lot-to-lot reproducibility. The columns are housed in a hydrophilic bioinert-coated stainless-steel hardware to eliminate secondary interactions, ensuring optimal performance during the initial injection process.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Sure_Pac_Bio_550_SEC_M_Di_HPLC_Columns_043f131056.jpg" alt="Thermo Scientific: SurePac Bio 550 SEC MDi HPLC Columns" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Sure_Pac_Bio_550_SEC_M_Di_HPLC_Columns_043f131056.jpg 156w," sizes="100vw" width="650" height="650"><ul><li>Ideal for AAV gene therapy characterization and quality control assessment due to selectivity of the dedicated smaller particle (3 μm) combined with wide-pore (550Å) size</li><li>Superior column-to-column and lot-to-lot reproducibility eliminates column variability as a concern in stability and QA/QC testing</li><li>High-efficiency peaks with excellent recovery</li><li>Higher resolution and throughput for fast turnaround time without sacrificing performance</li><li>Bioinert hardware to eliminate analyte adsorption</li></ul><h4>Specifications</h4><ul><li>Max. Pressure: 3500 psi (241 bar)</li><li>Packing Material: Monodisperse Silica Resin</li><li>Flow Rate: 0.6 mL/min</li><li>Temperature: 20°C to 60°C</li><li>Phase: Size Exclusion</li><li>Particle Size: 3 μm</li><li>pH: 2 to 8</li></ul>

Thermo Scientific SureSTART Vials and Well Plates Collection

Start your analysis with confidence using SureSTART vials, caps, well plates, and kits—offering full compatibility, quality materials, and performance across three levels.

<h4>Streamlined choice. Trusted quality.</h4>Start your analysis with confidence using Thermo Scientific™ SureSTART™ vials, caps, inserts, well plates, mats, and certified kits designed to meet your analytical, regulatory, and performance requirements. With full instrument compatibility, high material quality, and consistent performance across three defined levels, the SureSTART collection offers a smarter way to choose the right sample containment solution for your workflow.<h3>Why choose SureSTART?</h3><ul><li>Proven reliability: Every product is manufactured and certified to meet physical specifications—no weak links in your workflow.</li><li>Clear selection: Three performance levels help you balance sensitivity, robustness, and cost, now visually marked with one, two, or three waves on the vial.</li><li>Universal compatibility: Designed for seamless integration with all major GC, HPLC/UHPLC, and MS autosamplers across all vendors.</li><li>Certified cleanliness: Products are manufactured using the purest glass and plastics with low extractables and leachables, including GOLD-grade and silanized glass.</li><li>Maximum sample integrity: Minimize analyte loss and background peaks with precision-engineered sealing, surface chemistry, and material composition.</li><li>Bulk savings &amp; simplified inventory: Available in multiple pack sizes, performance levels, and formats to support your lab’s needs and budget.</li></ul><h3>The Three Performance Levels</h3><ul><li>Level 1 – Everyday analysis: For general-purpose GC/HPLC detection (e.g. UV/Vis, FID, RI). These chromatography-approved products are ideal for routine analyses with cost-efficiency in mind.</li><li>Level 2 – High-throughput analysis: Designed for regulated labs requiring robust and reproducible data, especially when using MS detectors for routine quantification.</li><li>Level 3 – High performance: For the most sensitive and selective analyses near the method detection limit. Packed in cleanroom environments and made with ultra-pure materials for maximum sample security and MS compatibility.</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Sure_START_Vials_and_Well_Plates_Collection_5a8b0da936.jpg" alt="Thermo Scientific SureSTART Vials and Well Plates Collection: Three performance levels help you balance sensitivity, robustness, and cost, now visually marked with one, two, or three waves on the vial." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Sure_START_Vials_and_Well_Plates_Collection_5a8b0da936.jpg 245w," sizes="100vw" width="1182" height="270"><h3>SureSTART Certified Vial and Cap Kits</h3><ul><li>Specification Certified: Routine analyses – Certified for physical specifications; no individual certificate.</li><li>LC/GC Certified: Chromatography-grade – Tested for 15 physical parameters with LC-UV &amp; GC-FID; certificate included.</li><li>MSCERT: For LC-MS/GC-MS – Certified low-adsorption kits tested with MS; includes SureStop™ vials with AVCS™ caps.</li><li>MSCERT+: For trace-level MS or DIA – Pre-cleaned, tested with LC-MS/GC-MS, and sold only as kits to ensure purity.</li><li>Application Certified: Pre-matched kits for specific instruments or validated applications.</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Sure_START_Vials_and_Well_Plates_Collection_2_fef6049d71.jpg" alt="Thermo Scientific SureSTART Vials and Well Plates Collection: There are several factors to consider when choosing a vial or well plate for your application. The table below will help guide you through this process to determine what type of product/performance level is most suitable for your application requirements." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Sure_START_Vials_and_Well_Plates_Collection_2_fef6049d71.jpg 204w," sizes="100vw" width="1515" height="1159"><h3>SureSTART Well Plates and Mats</h3>Thermo Scientific™ WebSeal™ well plates are ideal for laboratories seeking to increase autosampler capacity, reduce solvent usage, and streamline high-throughput workflows. Available in 96- and 384-well formats, they offer a certified alternative to traditional vials and are fully compatible with automated SPE/SLE platforms.<ul><li>Space-saving efficiency: Replace vials with well plates to increase sample capacity up to 8× and reduce storage footprint.</li><li>Flexible performance levels:<ul><li>Level 1: Standard plates for routine, non-regulated use (GC-tested).</li><li>Level 2: Low-bleed plates and high-performance mats, validated for LC-MS/GC-MS.</li><li>Level 3: Premium WebSeal Plate+ with glass-coated plastic wells—ideal for trace analytes and protein adsorption control.</li></ul></li><li>Solvent stability and clean sample contact: WebSeal Plate+ uses nanolayered silicon dioxide for minimal extractables and ultra-low adsorption.</li><li>Compatible sealing options:<ul><li>Silicone mats: For long-term storage and consistent results.</li><li>Pre-slit mats: For autosampler injection without evaporation or contamination.</li><li>Adhesive seals: For single-use workflows and re-sealing options with cavity protection.</li></ul></li></ul>Whether you work with polar solvents, proteins, or trace-level analyses, SureSTART well plates and sealing accessories help you optimize throughput, precision, and data confidence across all chromatography workflows.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Sure_START_Vials_and_Well_Plates_Collection_3_abce3dd960.jpg" alt="Thermo Scientific SureSTART Vials and Well Plates Collection: Selecting the perfect Thermo Scientific WebSeal well plates and mats for your chromatography requirements is easy using our selector tools and resources." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Sure_START_Vials_and_Well_Plates_Collection_3_abce3dd960.jpg 245w," sizes="100vw" width="1516" height="902">

Phenomenex Lux Cellulose-2 Chiral HPLC Columns

Phenomenex Lux Cellulose-2 chiral HPLC column, a halogenated cellulose phase, ensures superior enantiomer separation and is a proven alternative to CHIRALCEL® OZ®.

This first to market halogenated cellulose phenyl carbamate derivative offers unique chiral recognition abilities that complement the rest of the Lux family of columns.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomene_Lux_Cellulose_2_Chiral_HPLC_Columns_4aa21cccda.jpg" alt="Phenomenex: Lux Cellulose-2 Chiral HPLC Columns" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomene_Lux_Cellulose_2_Chiral_HPLC_Columns_4aa21cccda.jpg 245w," sizes="100vw" width="768" height="438"><ul><li>Separation Mode: Chiral</li><li>Stationary phase: Regenerated Cellulose (RC)<ul><li>Cellulose tris(3-chloro-4-methylphenylcarbamate)</li></ul></li><li>Recommended Use: Separation of enantiomers and racemic mixtures by reversed phase, normal phase, polar organic and SFC with a fully porous particle, coated with a polysaccharide stationary phase.</li></ul><h4>Achieve Greater Chiral Separation Success</h4>Lux Cellulose-2 columns are guaranteed to perform as well or better than the equivalent CHIRALCEL-OZ and OZ-H® Chiral Technologies column. Lux phases can also provide alternative selectivity to other chiral selectors for the most challenging chiral separations.Lux columns offer a wide and complementary range of enantioselectivity for even the most difficult chiral separation projects. The helical structure of the cellulose creates a complex steric environment that provides stronger interactions and better chiral recognition abilities. Additionally, the selector’s constituents produce hydrogen bonding, dipole, and π-π interactions that all affect the CSPs ability to separate your enantiomers effectively.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Lux_Performance_Advantage_cellulose_2_bbd747a32c.jpg" alt="Phenomenex: Lux Performance Advantage" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Lux_Performance_Advantage_cellulose_2_bbd747a32c.jpg 179w," sizes="100vw" width="677" height="590">

Phenomenex Lux Cellulose-3 Chiral HPLC Columns

Phenomenex Lux Cellulose-3 chiral HPLC column provides reliable enantiomer separation, performing as well or better than CHIRALCEL® OJ® with unique chiral selectivity.

This first to market halogenated cellulose phenyl carbamate derivative offers unique chiral recognition abilities that complement the rest of the Lux family of columns.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Lux_Cellulose_3_Chiral_HPLC_Columns_2_74f7d52275.jpg" alt="Phenomenex: Lux Cellulose-3 Chiral HPLC Columns" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Lux_Cellulose_3_Chiral_HPLC_Columns_2_74f7d52275.jpg 216w," sizes="100vw" width="903" height="650"><ul><li>Separation Mode: Chiral</li><li>Stationary phase: Regenerated Cellulose (RC)<ul><li>Cellulose tris(4-methylbenzoate)</li></ul></li><li>Recommended Use: Separation of enantiomers and racemic mixtures by reversed phase, normal phase, polar organic and SFC with a fully porous particle, coated with a polysaccharide stationary phase.</li></ul><h4>Achieve Greater Chiral Separation Success</h4>Lux Cellulose-3 columns are guaranteed to perform as well or better than the equivalent CHIRALCEL® OJ® and OJ-H® Chiral Technologies column. Lux phases can also provide alternative selectivity to other chiral selectors for the most challenging chiral separations. Lux columns offer a wide and complementary range of enantioselectivity for even the most difficult chiral separation projects.The helical structure of the cellulose creates a complex steric environment that provides stronger interactions and better chiral recognition abilities. Additionally, the selector’s constituents produce hydrogen bonding, dipole, and π π interactions that all affect the CSPs ability to separate your enantiomers effectively.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Lux_Performance_Advantage_cellulose_3_a232dc359a.jpg" alt="Phenomenex: Lux Cellulose-3 Performance Advantage" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Lux_Performance_Advantage_cellulose_3_a232dc359a.jpg 179w," sizes="100vw" width="677" height="590">

Phenomenex Lux i-Cellulose-5 Chiral HPLC Columns

Phenomenex Lux i-Cellulose-5 chiral HPLC column delivers broad enantioselectivity, strong solvent compatibility, and scalable performance for LC and SFC separations.

<h4>Your New First Choice Chiral Column!</h4>The immobilization and bonding technology used within the Lux i-Cellulose-5 promotes column stability in strong organic solvents, which affords you the ability to expand your chiral separation success with more solvent systems and separation modes.<ul><li>Wide Solvent Flexibility</li><li>Broad Enantioselectivity</li><li>Strong Solvent Compatibility</li><li>Recommended Use: Separation of enantiomers and racemic mixtures by reversed phase, normal phase, polar organic and SFC with a fully porous particle, immobilized with a polysaccharide stationary phase. This Immobilization provides additional strong organic solvent ruggedness so that DCM, DMSO and other related strong solvents can be used on column.</li></ul><h4>Achieve Greater Chiral Separation Success</h4>Lux® i-Cellulose-5 contains achemical crosslinking between the polysaccharide and silica supports which inturn provides incredible strong solvent (THF, DCM, DMSO, MtBE, Ethyl Acetate, etc.) robustness compared to coated phases and prevents the phase from being dissolved in strong solvents.Lower pressure, all purpose particle size for analytical LC (HPLC) or SFC methods and especially for high performance preparative LC or SFC puriﬁcation work.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Lux_i_Cellulose_5_Chiral_HPLC_Columns_28bc99dbb1.jpg" alt="Phenomenex: Lux i-Cellulose-5 Chiral HPLC Columns" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Lux_i_Cellulose_5_Chiral_HPLC_Columns_28bc99dbb1.jpg 245w," sizes="100vw" width="1541" height="595"><h4>Dependability and Seamless Scalability</h4>Our highest standards of quality will ensure that you are fully satisfied with each and every Lux chiral column as consistent quantitation and results come with every Lux batch and column that we manufacture. With matching selectivity, the 3 μm and 5 μm i-Cellulose-5 particle sizes allow you to scale down to increase resolution or easily scale up for preparative purification work.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Incredible_consistency_batch_to_batch_and_between_particle_sizes_4a8adc47b8.jpg" alt="Phenomenex: Incredible consistency batch-to-batch and between particle sizes" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Incredible_consistency_batch_to_batch_and_between_particle_sizes_4a8adc47b8.jpg 103w," sizes="100vw" width="677" height="1025">

Phenomenex Lux Amylose-1 Chiral HPLC Columns

Phenomenex Lux Amylose-1 chiral HPLC column ensures reliable enantiomer separation, matching or exceeding CHIRALPAK® AD® with strong recognition and broad selectivity.

This universally trusted amylose phenylcarbamate derivative is absolutely essential to any chiral screen. Lux Amylose-1 is a guaranteed alternative to CHIRALPAK® AD®. Expect equivalent or better performance when using this Lux phase.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Lux_Amylose_1_Chiral_HPLC_Columns_a5e2773084.jpg" alt="Phenomenex: Lux Amylose-1 Chiral HPLC Columns" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Lux_Amylose_1_Chiral_HPLC_Columns_a5e2773084.jpg 245w," sizes="100vw" width="1236" height="626"><ul><li>Stationary phase: Amylose tris(3,5-dimethylphenylcarbamate)</li><li>Recommended Use: Separation of enantiomers and racemic mixtures by reversed phase, normal phase, polar organic and SFC with a fully porous particle, coated with a polysaccharide stationary phase.</li></ul><h4>Achieve Greater Chiral Separation Success</h4>Lux columns are guaranteed to perform as well or better than the equivalent DAICEL® Chiral Technologies column. Lux phases can also provide alternative selectivity to other chiral selectors for the most challenging chiral separations. Lux columns offer a wide and complementary range of enantioselectivity for even the most difficult chiral separation projects.The helical structure of the amylose creates a complex steric environment that provides stronger interactions and better chiral recognition abilities. Additionally, the selector’s constituents produce hydrogen bonding, dipole, and π π interactions that all affect the CSPs ability to separate your enantiomers effectively.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Lux_Amylose_1_separation_c517f7e910.jpg" alt="Phenomenex: Separation comparison - Lux Amylose-1 vs. CHIRALPAK AD-H" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Lux_Amylose_1_separation_c517f7e910.jpg 179w," sizes="100vw" width="677" height="590">

Phenomenex Lux i-Amylose-3 Chiral HPLC Columns

Phenomenex Lux i-Amylose-3 chiral HPLC column offers broad enantioselectivity, strong solvent stability, and proven performance as an alternative to CHIRALPAK® IG®.

<h4>Your New First Choice Chiral Column!</h4>The immobilization and bonding technology used within the Lux i-Amylose-3 promotes column stability in strong organic solvents, which affords you the ability to expand your chiral separation success with more solvent systems and separation modes.<ul><li>Wide Solvent Flexibility</li><li>Broad Enantioselectivity</li><li>Strong Solvent Compatibility</li><li>Recommended Use: Separation of enantiomers and racemic mixtures with strong stability in strong organic solvents</li></ul><h4>Achieve Greater Chiral Separation Success</h4>The Lux i-Amylose-3, like the rest of the Lux product line, is an incredibly versatile phase that has been manufactured and developed to give you your desired results again and again. This is especially true under harsh conditions where coated phases are unable to perform.Lower pressure, all purpose particle size for analytical LC (HPLC) or SFC methods and especially for high performance preparative LC or SFC puriﬁcation work.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Lux_i_Cellulose_5_Chiral_HPLC_Columns_28bc99dbb1.jpg" alt="Phenomenex: Lux i-Amylose-3 Chiral HPLC Column" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Lux_i_Cellulose_5_Chiral_HPLC_Columns_28bc99dbb1.jpg 245w," sizes="100vw" width="1541" height="595"><h4>Guaranteed Alternative to CHIRALPAK® IG®</h4><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Guaranteed_Alternative_to_CHIRALPAK_IG_584996e87b.jpg" alt="Phenomenex: Guaranteed Alternative to CHIRALPAK® IG®" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Guaranteed_Alternative_to_CHIRALPAK_IG_584996e87b.jpg 176w," sizes="100vw" width="677" height="600">

Products focused on Consumables - page 4

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