News from LabRulezLCMS Library - Week 14, 2026

<h3><strong>We're excited to announce that </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/999"><strong>Clarity Chromatography Software</strong></a><strong> version 10.1.2 is now available!</strong></h3><p><strong>This minor update expands Clarity’s portfolio with new control modules.</strong></p><h4><strong>Newly added Instrument control modules</strong></h4><ul><li>Ecom auxiliary modules</li><li>HTA ICF control modules</li><li>Spark pump</li></ul><h4><strong>Updated Instrument control modules</strong></h4><ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/168"><strong>Ecom</strong></a> HPLC</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/328"><strong>Knauer</strong></a> HPLC</li><li>Spark ICF control modules</li><li>YoungIn Chromass HPLC</li></ul><blockquote><p>For a complete list of module changes, see the <a target="_blank" rel="noopener noreferrer" href="https://www.dataapex.com/version_history?product=1"><strong>Changelog</strong></a>. For more info about exciting new features directly in Clarity, explore what was introduced in the <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/article/5622"><strong>Clarity 10.1 release highlights</strong></a>.</p><p>Clarity can control <strong>1000+ instruments</strong>; the <a target="_blank" rel="noopener noreferrer" href="https://www.dataapex.com/controls"><strong>list can be previewed here</strong></a>.</p></blockquote><h4><strong>Supported Instruments in Clarity (DataApex) — Quick Guide</strong></h4><p>Clarity Chromatography Software supports a wide range of chromatographs and peripherals via <strong>digital control (DD)</strong> and <strong>analog acquisition (A/D)</strong> using the <strong>Colibrick</strong> module.</p><h5><strong>Gas Chromatographs (GC)</strong></h5><p>Digital integration over LAN/RS232 (many via ICF):</p><ul><li><strong>Agilent</strong>: 5890, 6890, 7890, 8860, 8890, <strong>Intuvo 9000</strong></li><li><strong>Shimadzu</strong>: GC-2010/2014, <strong>Nexis GC-2030</strong></li><li><strong>Thermo Fisher</strong>: TRACE 1300/1310</li><li><strong>PerkinElmer</strong>: Clarus 400–690</li><li>Also supported: <strong>Dani</strong>, <strong>Ellutia</strong>, <strong>Young In Chromass</strong>, <strong>Apix</strong>, <strong>Fuli</strong>, <strong>GOW-MAC</strong> (selected models)</li></ul><blockquote><p>Note: Most Agilent 6890–8890 and Intuvo use <strong>LAN – ICF</strong>.</p></blockquote><h5><strong>HPLC Systems</strong></h5><p>Full system/module control:</p><ul><li><strong>Agilent</strong> 1100–<strong>1290 Infinity II</strong> (ICF)</li><li><strong>Shimadzu</strong> LC-10/20 and <strong>Nexera LC-40</strong></li><li><strong>PerkinElmer</strong> Flexar / NexSAR</li><li><strong>Knauer</strong> Azura / BlueShadow / Smartline</li><li><strong>Hitachi</strong> Chromaster / Primaide</li><li><strong>Young In Chromass</strong> ChroZen series</li><li><strong>Sykam</strong> S500–S600, <strong>Watrex</strong> Streamline, <strong>Hanon</strong> LC7000–7300</li></ul><h5><strong>HPLC Modules (Pumps, Detectors, Ovens, Fraction Collectors)</strong></h5><ul><li><strong>Pumps</strong>: Agilent 1100–1290 families, Knauer, Shimadzu, PerkinElmer, Sykam, SSI, Ecom</li><li><strong>Detectors</strong>: VWD/DAD(PDA)/RID/FLD/ELSD across Agilent, Shimadzu, Knauer, PerkinElmer, Young In Chromass, Ecom, etc.</li><li><strong>Column Ovens</strong>: Agilent G1316x / G7116x, Shimadzu CTO-20/30/40, Knauer CT2.1, PerkinElmer Flexar</li><li><strong>Fraction Collectors</strong>: Knauer FC 6.1, Teledyne FOXY series, Ecom ECF 2096, Waters Fraction Collector II</li></ul><h5><strong>Autosamplers</strong></h5><ul><li><strong>Agilent</strong> GC ALS (7673/7683/7693/8697), HPLC ALS modules (G1313A–G7167C)</li><li><strong>Shimadzu</strong> AOC-20 / AOC-5000+, SIL-10 / SIL-20 / <strong>SIL-40</strong> series</li><li><strong>CTC Analytics PAL</strong>, <strong>HTA</strong> autosamplers, <strong>Spark</strong> Alias/UHPLC, <strong>Knauer</strong> AS 6.1L</li><li><strong>PerkinElmer</strong> Flexar / NexSAR AS</li></ul><h5><strong>Other Devices</strong></h5><ul><li><strong>GC×GC modulators</strong> (e.g., Charles University GC×GC Modulator)</li><li><strong>Valves &amp; switch modules</strong> (Agilent, Knauer, Shimadzu, VICI-Valco)</li><li><strong>Degassers, flow monitors, managers, interfaces</strong></li><li><strong>LC-MS / GC-MS</strong>: Advion Expression CMS, Microsaic 4500 MiD, Markes BenchTOF (and others)</li><li><strong>Balances (EA extension)</strong>: Mettler Toledo, Sartorius</li></ul><h5><strong>Analog Acquisition (Colibrick)</strong></h5><p>A/D support for legacy or analog-output devices:</p><ul><li><strong>GC</strong>: Agilent 5880/4890A, Varian 3xxx/3800/3900, PerkinElmer Clarus series, Thermo TRACE, Shimadzu GC-14/9A, Scion 43x/45x/83xx/85xx, etc.</li><li><strong>HPLC Detectors</strong>: Waters 2487/2489, ESA Corona, Hitachi L-series, JASCO FP/UV, Ecom LCD series, many others</li><li><strong>Elemental &amp; Amino Acid Analyzers</strong>: Carlo Erba/Costech ECS, Biochrom 20/30+</li></ul><p>If you are interested in a <strong>DEMO VERSION</strong>, contact us!</p>

DataApex Clarity Chromatography software 10.1.2 just released!

<p><strong>🎤Dan Reddy </strong>(PhD candidate in the Department of Chemistry at Queen's University and a recipient of the NSERC Vanier Canada Graduate Scholarship. He was recently named one of the top 35 early-career scientists globally in the 2025 CAS Future Leaders program.)</p><p><strong>In this episode, we interview Daniel Reddy, 2025 CAS Future Leader and PhD candidate at Queen's University, about his groundbreaking research on automated mass spectrometry and dried matrix spots (DMS).</strong></p><p>Dan's work combines computer vision, 3D printer automation, and laser micromachining to revolutionize sample preparation—reducing CO₂ emissions by 28-fold and organic solvent use by 21-fold compared to traditional methods.</p><h4><strong>What You'll Learn:</strong></h4><ul><li>How to give a mass spectrometer "sight" and "taste" using computer vision and the LMJ-SSP (Liquid Microjunction Surface Sampling Probe)</li><li>The breakthrough technology behind Surface Energy Traps (SETs) for confining liquid droplets on paper substrates</li><li>Why dried matrix spots eliminate the need for cold-chain shipping and enable analysis of blood, urine, and saliva samples via standard mail</li><li>How DIY chemists are hacking 3D printers to build cost-effective autosamplers (replacing $10K+ systems)</li><li>The role of green chemistry and systems thinking in modernizing analytical methods</li><li>Why interdisciplinary collaboration (chemistry + computer science) is critical to innovation</li></ul><h4><strong>Key Topics:</strong></h4><ul><li>Dried Matrix Spots (DMS) for automated sample prep</li><li>Laser-micromachined Surface Energy Traps</li><li>Direct surface sampling mass spectrometry</li><li>Sustainability in analytical chemistry</li><li>3D printer customization for laboratory automation</li><li>The importance of science communication and community outreach</li></ul><h3><strong>Video Transcription</strong></h3><h4><span><strong>Introduction</strong></span></h4><p>Recent advances in analytical chemistry increasingly focus on simplifying workflows, improving sustainability, and enabling automation. In this context, the work of <span>Dan Reddy</span> centers on the concept of <i>“bringing mass spectrometry to life”</i> through the integration of automated sampling, computer vision, and dried matrix spot (DMS) methodologies.</p><p>The primary objective is to enable efficient and reproducible analysis of biological and liquid samples—such as blood, urine, saliva, or other solutions—by depositing them onto substrates, drying them, and extracting meaningful analytical information directly via mass spectrometry.</p><h4><span><strong>Conceptual Framework: Enabling “Sight” and “Taste” in Mass Spectrometry</strong></span></h4><p>A central innovation in this work is the conceptual transformation of mass spectrometry from a passive analytical tool into an active, semi-autonomous system.</p><ul><li><strong>“Sight”</strong> is introduced through <strong>camera-based computer vision</strong>, allowing the system to identify predefined patterns on a substrate.</li><li><strong>“Taste”</strong> is implemented via a <strong>liquid microjunction surface sampling probe (LMJSSP)</strong>, which enables direct extraction of analytes from surfaces.</li></ul><p>The LMJSSP consists of two concentric capillaries forming a continuously flowing microdroplet. When brought into contact with the sample surface, this droplet facilitates localized extraction, effectively enabling direct surface analysis without traditional chromatographic separation.</p><p>Combined with an automated positioning system (adapted from 3D printer mechanics), the platform can autonomously locate sampling sites and perform reproducible measurements.</p><h4><span><strong>Dried Matrix Spots as an Analytical Platform</strong></span></h4><h5><span><strong>Principle and Advantages</strong></span></h5><p>Dried matrix spots involve depositing a small volume of liquid sample onto a substrate (commonly paper), followed by drying. This approach offers several advantages:</p><ul><li>Reduced need for cold-chain transport</li><li>Simplified sample handling and storage</li><li>Compatibility with remote or decentralized sampling</li><li>Lower solvent consumption</li></ul><p>These features contribute significantly to greener analytical workflows and improved logistical efficiency.</p><h5><span><strong>Sustainability Impact</strong></span></h5><p>The implementation of DMS-based workflows has demonstrated:</p><ul><li>Up to <strong>28-fold reduction in CO₂ emissions</strong></li><li>Up to <strong>21-fold reduction in organic solvent use</strong></li></ul><p>These improvements arise from eliminating cold-chain logistics and minimizing solvent-intensive preparation steps.</p><h4><span><strong>Surface Energy Traps (SCTs): Controlled Micro-Sampling Environments</strong></span></h4><h5><span><strong>Definition and Fabrication</strong></span></h5><p>Surface Energy Traps (SCTs) are microstructured regions on a substrate designed to confine liquid droplets within defined boundaries.</p><p>The fabrication process involves:</p><ol><li>Coating paper with a <strong>hydrophobic layer</strong></li><li>Using <strong>laser ablation</strong> to selectively remove the coating in defined patterns</li><li>Creating <strong>hydrophilic circular regions</strong> (typically ~0.5 mm diameter)</li></ol><p>These patterned regions act as micro-wells that confine droplets spatially and prevent lateral diffusion.</p><h5><span><strong>Analytical Benefits</strong></span></h5><p>SCTs address key limitations of traditional dried matrix spots:</p><ul><li><strong>Improved spatial confinement</strong> of analytes</li><li><strong>Reduced diffusion variability</strong></li><li><strong>Enhanced reproducibility</strong></li><li><strong>Preconcentration effects</strong> due to controlled drying</li></ul><p>Additionally, the SCT diameter is smaller than the sampling probe, enabling near-complete analyte collection during surface extraction.</p><h4><span><strong>Drying Dynamics and Analyte Distribution</strong></span></h4><p>Traditional dried matrix spots often suffer from the <strong>“coffee-ring effect”</strong>, where analytes redistribute unevenly during drying. This leads to variability depending on sampling location.</p><p>The SCT approach mitigates these effects by:</p><ul><li>Limiting diffusion area</li><li>Maintaining analytes near the surface</li><li>Producing more uniform analyte distribution</li></ul><p>Preliminary investigations (e.g., via SEM imaging) indicate improved homogeneity, although further studies are needed to fully characterize drying kinetics and their influence on signal intensity.</p><h4><span><strong>Integration with Automated Sampling Systems</strong></span></h4><h5><span><strong>3D Printer-Based Positioning</strong></span></h5><p>A key engineering innovation is the repurposing of <strong>3D printer hardware</strong> for automated sample positioning:</p><ul><li>Provides cost-effective XYZ motion control</li><li>Enables programmable sampling routines</li><li>Supports integration with analytical instrumentation</li></ul><p>Custom software—developed in collaboration with computer engineers—allows users to define coordinates, dwell times, and sampling parameters.</p><h5><span><strong>Computer Vision Integration</strong></span></h5><p>The addition of computer vision enables:</p><ul><li>Pattern recognition (e.g., alignment markers near SCTs)</li><li>Autonomous targeting of sampling locations</li><li>Reduced operator intervention</li></ul><p>This transforms the system into a semi-autonomous analytical platform.</p><h4><span><strong>Comparison with Conventional Workflows</strong></span></h4><p>Compared to traditional LC-MS or GC-MS workflows, the presented approach offers:</p><div><div><figure class="table"><table><thead><tr><th>Aspect</th><th>Conventional Methods</th><th>SCT + LMJSSP Approach</th></tr></thead><tbody><tr><td>Sample prep</td><td>Multi-step, solvent-intensive</td><td>Minimal, direct surface sampling</td></tr><tr><td>Chromatography</td><td>Required</td><td>Potentially bypassed</td></tr><tr><td>Throughput</td><td>Moderate</td><td>High (automated)</td></tr><tr><td>Sustainability</td><td>Limited</td><td>Significantly improved</td></tr></tbody></table></figure></div></div><p>While chromatographic methods remain essential for many applications, this approach provides a complementary pathway for rapid screening and targeted analyses.</p><h4><span><strong>Green Chemistry and Systems Thinking</strong></span></h4><p>A notable aspect of this work is the integration of <strong>systems thinking</strong> into analytical chemistry. Inspired by engagement with organizations such as the <span>American Chemical Society</span> and green chemistry initiatives, the research emphasizes:</p><ul><li>Environmental impact reduction</li><li>Resource efficiency</li><li>Lifecycle considerations</li></ul><p>This perspective expands the role of analytical chemists beyond method performance to broader societal and environmental implications.</p><h4><span><strong>Future Outlook and Applications</strong></span></h4><p>The research is currently at an early stage but shows strong potential for:</p><ul><li><strong>Decentralized diagnostics</strong> (e.g., remote blood sampling)</li><li><strong>Environmental monitoring</strong></li><li><strong>High-throughput screening workflows</strong></li><li><strong>Field-deployable analytical systems</strong></li></ul><p>Further advancements are expected in:</p><ul><li>Substrate engineering</li><li>Automation robustness</li><li>Integration with advanced MS platforms (e.g., triple quadrupole systems)</li></ul><h4><span><strong>Conclusion</strong></span></h4><p>The integration of dried matrix spots, surface energy traps, and automated surface sampling represents a significant step toward more sustainable, efficient, and accessible analytical workflows.</p><p>By combining innovations in microfabrication, computer vision, and mass spectrometry, the work of <span>Dan Reddy</span> demonstrates how analytical chemistry can evolve toward smarter, greener, and more autonomous systems.</p><blockquote><p><strong>This text has been automatically transcribed from a video presentation using AI technology. It may contain inaccuracies and is not guaranteed to be 100% correct.</strong></p></blockquote><blockquote><h4><strong>Concentrating on Chromatography Podcast</strong></h4><p>Dive into the frontiers of chromatography, mass spectrometry, and sample preparation with host David Oliva. Each episode features candid conversations with leading researchers, industry innovators, and passionate scientists who are shaping the future of analytical chemistry. From decoding PFAS detection challenges to exploring the latest in AI-assisted liquid chromatography, this show uncovers practical workflows, sustainability breakthroughs, and the real-world impact of separation science. Whether you’re a chromatographer, lab professional, or researcher you'll discover inspiring content!</p><p>You can find <strong>Concentrating on Chromatography Podcast </strong>in podcast apps:</p><ul><li><a target="_blank" rel="noopener noreferrer" href="https://open.spotify.com/show/1wZg67rCjoGju4yhqxI3tL"><strong>Spotify</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podcasts.apple.com/tz/podcast/concentrating-on-chromatography/id1788429185"><strong>Apple podcast</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podscan.fm/podcasts/concentrating-on-chromatography"><strong>podscan</strong></a></li></ul><p>and on <a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/@ChromatographyTalk/videos"><strong>YouTube channel</strong></a></p></blockquote>

Mass Spectrometry, Surface Sampling and Dried Matrix Spots - Greener Chemistry and 3D Printing

Article

Product

Application

Video

Scientists

Interview

Science and research

Software

Since 1991 DataApex develops and manufactures chromatography data stations. DataApex is constantly striving to provide users with efficient and up-to-date tools for chromatography data processing.

DataApex

Everything from the world of analytical chemistry in one place. We connect people in solving their problems. At Labrulez you will find all the necessary information easily, quickly and clearly. Stop searching and start finding.

LabRulez

Organomation, founded in 1959, designs and manufactures high-quality nitrogen evaporators and extraction systems. Known for innovation and durability, their lab instruments are used globally for efficient sample preparation with strong customer support.

Organomation

ECOM ECS06 Gradient Analytical System

Highly effective HPLC system with a UV-VIS detector, a column oven, an analytical pump, a gradient box, and an autosampler with/without cooling and heating, 40 MPa (5801 psi).

<div style="display:block;" aria-labelledby="tab_item-0"><p><strong>Highly effective HPLC system with a UV-VIS detector, a column oven, an analytical pump, a gradient box, and an autosampler with/without cooling and heating, 40 MPa (5801 psi).</strong></p><p>The detector with eight channels in the range of 200-800 nm and a very low noise level also offers high-speed scanning <strong>up to 100 Hz</strong>. The units are communicated through <strong>RS232</strong> or Ethernet (LAN). An additional PC A/D converter card is not required for this system. The system contains an autosampler and Clarity software. All units are supported in <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/999"><strong>Clarity software</strong></a> from installation.</p><p>A wireless mouse and keyboard set (P/N: EPC-0028), a PC (P/N: EPC-0026), and a computer monitor (P/N: EPC-0027) can be purchased with the system.</p><h3><strong>Main parts</strong></h3><h5><strong>ECDA2800 UV-VIS PDA DETECTOR</strong></h5><p>Analytical Diode Array Detector measures at eight wavelengths simultaneously or performs a full scan with a speed of up to 100 Hz. 3D support in Clarity SW. Noise level ±5 x 10-6 AU. Four analog outputs. Two special mathematical channels are available. AD 05 analytical cell is included.</p><h5><strong>ECO2080L COLUMN OVEN WITH HEATING AND COOLING</strong></h5><p>This column oven allows precise temperature stabilization in the range of 0-80°C. A big compartment room can accommodate up to 3 columns with lengths up to 30 cm. Peltier technology offers the possibility of heating and cooling independently from room temperature.</p><h5><strong>ECP2010 ANALYTICAL HPLC PUMP</strong></h5><p>This isocratic pump works with Gradient Box ECB2004B as a quaternary gradient pump. The flow rate range is 0.001-10.00 ml/min and the pressure limit is 40 MPa. Unit software includes a new learning algorithm for pulsation suppression and many testing and diagnostic functions.</p><h5><strong>ECB2004B GRADIENT BOX WITH DEGASSER</strong></h5><p>The box is suited for handling liquids in ECOM gradient systems. It accommodates a container for solvent bottles, a built-in high-efficiency vacuum degasser, and a four-way gradient valve. Up to four solvent lines may be degassed simultaneously by one unit. A four-way gradient valve is controlled from the pump ECP2010.</p><h5><strong>AUTOSAMPLER AS96</strong></h5><p>A reliable and precise autosampler for a wide range of applications in HPLC and LC-MS in variants with or without a cooling and heating module. State-of-the-art injection technology with fast injection and wash cycles. For 2x48 vials, max. pressure 40 MPa (5801 psi)</p><h5><strong>CLARITY CHROMATOGRAPHY SOFTWARE</strong></h5><p>This system is fully controlled by Clarity Chromatography software, which is also a part of delivery. Clarity software complies with CFR21GLP requirements.</p><h3>SYSTEM CONTAINS&nbsp;</h3><p><strong>Pcs / Description (P/N)</strong></p><ul><li>1x / ECDA2800 Analytical UV-VIS PDA Detector (ANW0000X)</li><li>1x /&nbsp;ECB2004B Gradient box with degasser (ABA0000X)</li><li>1x / ECP2010 Analytical HPLC pump (ACA0000X)</li><li>1x / ECO2080L Column oven with heating and cooling (AOA00004)</li><li>1x / Autosampler AS96 for 2x48 vials, 40 MPa, with or without heating and cooling module (ASA97010/ASA97000)</li><li>1x / Clarity – Station for 1 instrument (AP000C50)</li><li>1x / Clarity module for HPLC control (AP000A24)</li><li>1x / Clarity SW module for AS controlvAP000A26)</li><li>1x / Module for PDA data Clarity SW (AP000A29)</li><li>1x / Accessories for analyt. system series 2000 (ASA00180)</li><li>1x / Accessories for autosampler (ASA96180)</li></ul><p>Note: Column and computer not included. PC system has to be equipped for handling 3 serial RS232 or 1 Ethernet port at least. Please, check also <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/999"><strong>Clarity software</strong></a> requirements..</p><h3>Configuration options</h3><ul><li><strong>ASA0600X</strong> - Gradient analytical system - incl. autosampler <strong>without cooling and heating</strong>, up to 40 MPa (5801 psi)</li><li><strong>ASA06C0X</strong> - Gradient analytical system – incl. autosampler <strong>with cooling and heating</strong>, up to 40 MPa (5801 psi)</li></ul></div>

ECOM ECS07 Gradient Analytical System

Highly effective HPLC system with a UV-VIS detector, a column oven, an analytical pump (60 MPa, 8702 psi), a gradient box, and an autosampler.

<div style="display:block;" aria-labelledby="tab_item-0"><p><strong>Highly effective HPLC system with a UV-VIS detector, a column oven, an analytical pump, a gradient box, and an autosampler with/without cooling and heating, 60 MPa (8702 psi).</strong></p><p>The detector with eight channels in the range of 200-800 nm and a very low noise level also offers high-speed scanning <strong>up to 100 Hz</strong>. The units are communicated through <strong>RS232</strong> or <strong>Ethernet (LAN)</strong>. An additional PC A/D converter card is not required for this system. The system contains an autosampler and Clarity software. All units are supported in <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/999"><strong>Clarity software</strong></a> from installation.</p><p>A wireless mouse and keyboard set (P/N: EPC-0028), a PC (P/N: EPC-0026), and a computer monitor (P/N: EPC-0027) can be purchased with the system.</p><h3><strong>Main parts</strong></h3><h5><strong>ECDA2800 UV-VIS PDA DETECTOR</strong></h5><p>Analytical Diode Array Detector measures at eight wavelengths simultaneously or performs a full scan with a speed of up to 100 Hz. 3D support in Clarity SW. Noise level ±5 x 10-6 AU. Four analog outputs. Two special mathematical channels are available. AD 05 analytical cell is included.</p><h5><strong>ECO2080L COLUMN OVEN WITH HEATING AND COOLING</strong></h5><p>This column oven allows precise temperature stabilization in the range of 0-80°C. A big compartment room can accommodate up to 3 columns with lengths up to 30 cm. Peltier technology offers the possibility of heating and cooling independently from room temperature.&nbsp;</p><h5><strong>ECP2010H ANALYTICAL HPLC PUMP</strong></h5><p>This isocratic pump works with Gradient Box ECB2004B as a <strong>quaternary gradient pump</strong>. The flow rate range is <strong>0.001-10.00 ml/min</strong> and the pressure limit is <strong>60 MPa</strong>. Unit software includes a new learning algorithm for pulsation suppression and many testing and diagnostic functions.</p><h5><strong>ECB2004B GRADIENT BOX WITH DEGASSER</strong></h5><p>The box is suited for handling liquids in ECOM gradient systems. It accommodates a container for solvent bottles, a built-in high-efficiency vacuum degasser, and a four-way gradient valve. Up to four solvent lines may be degassed simultaneously by one unit. A four-way gradient valve is controlled from the pump ECP2010.</p><h5><strong>AUTOSAMPLER AS96</strong></h5><p>A reliable and precise autosampler for a wide range of applications in HPLC and LC-MS in <strong>variants with or without a cooling and heating module</strong>. State-of-the-art injection technology with fast injection and wash cycles. Max. pressure <strong>60 MPa.</strong></p><h5><strong>CLARITY CHROMATOGRAPHY SOFTWARE</strong></h5><p>This system is fully controlled by Clarity Chromatography software, which is also a part of delivery. Clarity software complies with CFR21GLP requirements.</p><h3>SYSTEM CONTAINS&nbsp;</h3><p><strong>Pcs / Description (P/N)</strong></p><ul><li>1x / ECDA2800 Analytical UV-VIS PDA Detector (ANW0000X)</li><li>1x /&nbsp;ECB2004B Gradient box with degasser (ABA0000X)</li><li>1x / ECP2010H Analytical HPLC pump (ACF0000X)</li><li>1x / ECO2080L Column oven with heating and cooling (AOA00004)</li><li>1x / Autosampler AS96 for 2x48 vials, 60 MPa, with or without heating and cooling module (ASA96000/ASA96010)</li><li>1x / Clarity – Station for 1 instrument (AP000C50)</li><li>1x / Clarity module for HPLC control (AP000A24)</li><li>1x / Clarity SW module for AS controlvAP000A26)</li><li>1x / Module for PDA data Clarity SW (AP000A29)</li><li>1x / Accessories for analyt. system series 2000 (ASA00180)</li><li>1x / Accessories for autosampler (ASA96180)</li></ul><p>Note: Column and computer not included. PC system has to be equipped for handling 3 serial RS232 or 1 Ethernet port at least. Please, check also <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/999"><strong>Clarity software</strong></a> requirements..</p><h3>Configuration options</h3><ul><li><strong>ASA0700X</strong> - Gradient analytical system - incl. autosampler <strong>without cooling and heating</strong>, up to 60 MPa.</li><li><strong>ASA07C0X </strong>- Gradient analytical system – incl. autosampler <strong>with cooling and heating</strong>, up to 60 MPa.</li></ul></div>

ECOM LED20M FIX Dual UV Detector with display

The LED20M FIX Dual UV Detector with a display uses Light Emitting Diodes (LED) as the light source. It is used for flash chromatography.

<div style="display:block;" aria-labelledby="tab_item-0"><p>The <strong>LED20M FIX Dual UV Detector</strong> with a display uses <strong>Light Emitting Diodes (LED) </strong>as the light source. It is used for flash chromatography.</p><h3><strong>Why choose LED20M FIX detectors for your application</strong></h3><ul><li>The LED detectors allow easy and convenient detection in the UV-VIS range. They are manufactured in single or dual channel models with fixed wavelength setup.</li><li>The detectors are widely used in chromatography techniques using gravity glass columns for purification and isolation of organic small molecules and other compounds of interest. Long-lasting and reliable light source is provided by LED.</li><li>The <strong>optical flow cell </strong>is <strong>easily accessible </strong>and <strong>replaceable</strong>, this feature allows flexible choice of detection sensitivity if required. Low cell heating due to <strong>low power dissipation of LEDs</strong> makes this detector ideal for applications where analytes may be susceptible to degradation due to elevated temperatures. Absorbance information is displayed in detail on the <strong>integrated OLED display </strong>in <strong>numerical and graphical formats</strong>.</li><li>The units have convenient USB-C connectivity and power. When the detector is connected to a PC, the recorded data can be stored and processed using the ECOMAC software. ECOMAC basic software license is available with the price of the product without any additional fees. All these features and capabilities allow LED20M FIX to be an affordable, cost-effective, reliable and robust choice of an UV-VIS detector.</li></ul><h4><strong>Wavelengths</strong></h4><ul><li>The dual UV detector version measures at two fixed wavelengths, which are adjusted in production and given by the built-in LEDs.</li><li>By default, diodes with wavelengths of 255 and 280 nm are used. Optionally, the customer can select a wavelength in the range of 255–⁠⁠⁠⁠⁠⁠600 nm in steps of 5 nm.</li></ul><h4><strong>Control</strong></h4><ul><li>The detector can work without any additional SW support, but it is also possible to interconnect it via USB-C cable to a PC with <strong>ECOMAC SW</strong>, to get a data set for later use or to get reports for unit diagnostics.</li><li>The unit has an innovative PCB board that powers the LEDs, controls the unit, and has many new features, including higher sampling speed.</li></ul><h4><strong>Key features and benefits</strong></h4><ul><li><strong>OLED display</strong></li><li><strong>Numerical and graphical view mode</strong></li><li><strong>Long lifetime</strong> of the <strong>LED</strong> light source</li><li><strong>Low cell heating </strong>due to <strong>low power losses of the LEDs</strong></li><li><strong>USB C</strong> powering and communication port</li><li><strong>ECOMAC Basic software for free</strong></li><li><strong>Autozero</strong> function</li><li><strong>Easy flow cell replacement</strong></li><li>Small dimensions</li><li><strong>ECOMAC SW </strong>- &nbsp;sophisticated software for data acquisition and for diagnostics</li></ul></div>

ECOM LED20M FIX Single UV Detector with display

The LED20M FIX Single UV Detector with a display uses Light Emitting Diodes (LED) as the light source. It is used for flash chromatography.

<div style="display:block;" aria-labelledby="tab_item-0"><p>The <strong>LED20M FIX Single UV Detector</strong> with a display uses <strong>Light Emitting Diodes (LED) </strong>as the light source. It is used for flash chromatography.</p><h3><strong>Why choose LED20M FIX detectors for your application</strong></h3><ul><li>The LED detectors allow easy and convenient detection in the UV-VIS range. They are manufactured in single or dual channel models with fixed wavelength setup.</li><li>The detectors are widely used in chromatography techniques using gravity glass columns for purification and isolation of organic small molecules and other compounds of interest. Long-lasting and reliable light source is provided by LED.</li><li>The <strong>optical flow cell </strong>is <strong>easily accessible </strong>and <strong>replaceable</strong>, this feature allows flexible choice of detection sensitivity if required. Low cell heating due to <strong>low power dissipation of LEDs</strong> makes this detector ideal for applications where analytes may be susceptible to degradation due to elevated temperatures. Absorbance information is displayed in detail on the <strong>integrated OLED display </strong>in <strong>numerical and graphical formats</strong>.</li><li>The units have convenient USB-C connectivity and power. When the detector is connected to a PC, the recorded data can be stored and processed using the ECOMAC software. ECOMAC basic software license is available with the price of the product without any additional fees. All these features and capabilities allow LED20M FIX to be an affordable, cost-effective, reliable and robust choice of an UV-VIS detector.</li></ul><h3><strong>Wavelengths</strong></h3><ul><li>The single UV detector version measures at 1 fixed wavelength, which is adjusted in production and given by the built-in LEDs.</li><li>By default, diodes with wavelengths of 255 or 280 nm are used. Optionally, customers can select a wavelength within the range of 255–⁠⁠⁠⁠⁠⁠600 nm in steps of 5 nm.</li></ul><h3><strong>Control</strong></h3><ul><li>The detector can work without any additional SW support, but it is also possible to interconnect it via USB-C cable to a PC with <strong>ECOMAC SW</strong>, to get a data set for later use or to get reports for unit diagnostics.</li><li>The unit has an innovative PCB board that powers the LEDs, controls the unit, and has many new features, including higher sampling speed.</li></ul><h3><strong>Key features and benefits</strong></h3><ul><li><strong>Practical OLED display</strong></li><li><strong>Numerical and graphical view mode</strong></li><li><strong>Long lifetime</strong> of the <strong>LED</strong> light source</li><li><strong>Low cell heating </strong>due to <strong>low power losses of the LEDs</strong></li><li><strong>USB -C</strong> powering and communication port</li><li><strong>Autozero</strong> function</li><li><strong>Easy flow cell replacement</strong></li><li>Small dimensions</li><li><strong>ECOMAC SW </strong>- &nbsp;sophisticated software for data acquisition and for diagnostics</li></ul><p><strong>Note:</strong> A preparative cell PFC 200 Basic is supplied with the unit. Other flow cells are available at request.</p></div>

ECOM LED20G Dual UV Detector

LED20G Dual UV detector for preparative and flash chromatography. ECOM's unique patented technology radically improves the detectors´ features. LEDs are used as the source of light.

<div style="display:block;" aria-labelledby="tab_item-0"><p><strong>LED20G Dual UV LED detector for preparative and flash liquid chromatography.</strong> LEDs (Light Emitting Diodes) are used as the light source. <strong>A unique and patented ECOM technology radically improves the detector characteristics.&nbsp;</strong></p><p>The LEDs themselves typically have a peak wavelength with a tolerance of +/- 5 nm and a spectral half-width of 10-20 nm, which is unacceptable for some applications, as e.g. for FPLC. This ECOM solution, however, allows the spectral width to be narrowed and, thanks to our patented technology, the exact wavelength to be selected from the LED spectrum.</p><p>This version of the dual UV detector measures at two fixed wavelengths given by the installed LEDs.</p><p>The default wavelengths are 254 and 280 nm. Optionally, the customer can select a wavelength in the range 254-600 nm in 1 nm steps.</p><p>The unit is controlled by an innovative printed circuit board that powers the LEDs, controls the unit, and has many new features including higher sampling speed.</p><h3><strong>Key features and benefits</strong></h3><ul><li>Sharp, high, and symmetrical peaks thanks to the ECOM patented technology</li><li>Excellent linearity</li><li>Excellent price-performance ratio</li><li>Compact device dimensions</li><li>Low cell heating due to LED low power supply (0.7 W) allows use for peptide analysis or FPLC</li><li>Easy flow cell replacement</li><li>Higher sampling speed</li><li>Sophisticated diagnostic software</li><li>Diodes with wavelengths of 254 and 280 nm and a PFC cell with an optical path length of 2 mm are used as standard.</li><li>Other cells and wavelengths on request.</li></ul><h3><strong>Parameters</strong></h3><ul><li><strong>Number of channels (Signals):</strong> Two fix wavelength</li><li><strong>Typical spectral half-width&nbsp;:</strong> 4</li><li><strong>Light source:</strong> LEDs</li><li><strong>Noise level at test cell (254 nm, TC 0.75 s):</strong> ± 10x10-6 AU</li><li><strong>Drift at test cell (254 nm after 1 h):</strong> 1x10-3 AU/hr</li><li><strong>Communication:</strong> Remote digital I/O</li><li><strong>Power supply:</strong> 12-24 V DC</li><li><strong>Power input:</strong> 2 W</li><li><strong>Materials in contact with mobile phase:</strong> FEP; fused silica, stainless steel (cell)</li><li><strong>Communication interface:</strong> USB-C</li><li><strong>Optical cables:</strong> no</li><li><strong>Dimensions W x H x D:</strong> 193 x 70 x 40 mm (7.60 x 2.76 x 1.57 in)</li><li><strong>Weight:</strong> 0.66 kg (1.46 Ibs)</li></ul></div>

ECOM L3320 HPLC Autosampler

An automatic autosampler with excellent accuracy and linearity of sample injection. Innovated needle design reduces sample contamination and µl pick-up mode achieves zero sample loss.

<p>Autosampler L3320 is an automatic autosampler with excellent accuracy and linearity of sample injection. Innovated needle design significantly reduces sample residue contamination. µl pick-up mode achieves zero sample loss.</p><p>The autosampler is designed as a&nbsp;<strong>standalone unit</strong>.</p><p>The user-friendly unit features computer control and shows information about the actual status on the unit display. Automated self-checking simplifies the usage of the autosampler, there is no need for calibration or needle position setting.</p><p>Rheodyne valve secures the reliable operation of the device.</p><p>The unit is supported by the <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/999"><strong>Clarity&nbsp;software</strong></a>.</p><h4><strong>Parameters</strong></h4><ul><li><strong>Communication</strong>: RS232,USB</li><li><strong>Syringe volume</strong>: Standard 250μl; 100μl optional</li><li><strong>Reproducibility</strong>: Full loop injection: RSD≤0.3%, Partial loopfill injection: RSD≤0.5%, μl pickup injection: RSD≤1%</li><li><strong>Control</strong>:&nbsp;PC (Clarity SW)</li><li><strong>Loop volumes</strong>: Standard 100μl; 10μl, 20μl and 50μl optional</li><li><strong>Injection Volume</strong>: Full loop injection = loop volume, Partial loop injection = ½ of loop volume, μl pickup injection = (loop volume – 3 x needle volume)/2</li><li><strong>Sample Capacity</strong>: 2 standard 48-vial tray (1.5ml vials)</li><li><strong>Pressure limit</strong>: 6000 PSI</li><li><strong>Cross Contamination</strong>: &lt; 0.02% after programmed needle wash</li><li><strong>Weight</strong>: 17kg</li><li><strong>Dimensions W x H x D</strong>: 453 x 359 x 244 mm (17.8 x 14.1 x 9.6”)</li><li><strong>Linearity</strong>: 0.9999</li><li><strong>Power supply</strong>: 100-240VAC, 50-60Hz, 110W&nbsp;</li></ul>

Products focused on HPLC from ECOM - page 1

Related content

Mass Spectrometry, Surface Sampling and Dried Matrix Spots - Greener Chemistry and 3D Printing

DataApex Clarity Chromatography software 10.1.2 just released!

News from LabRulezLCMS Library - Week 14, 2026