<h4>2nd Annual International NETPHARM Conference: From Cutting-Edge Equipment to Excellent Results at the Midpoint of the Project</h4>On 15–16 April 2026, the second annual international conference of the project “New Technologies for Translational Research in Pharmaceutical Sciences” (NETPHARM) took place in Kudowa-Zdrój, Poland. The meeting, attended by more than 100 researchers, confirmed that after two years of implementation the project is successfully fulfilling its ambitious goals in linking basic research with clinical practice.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Mgr_Martina_Kopecka_Jurcekova_Prof_Petr_Pavek_8db8f7e5f2.jpg" alt="Mgr. Martina Kopecká Jurčeková: Prof. Petr Pávek" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Mgr_Martina_Kopecka_Jurcekova_Prof_Petr_Pavek_8db8f7e5f2.jpg 234w," sizes="100vw" width="1200" height="800"><h4>Scientific excellence and international outreach</h4>The scientific programme of the conference focused on progress in five key research objectives (RO1–RO5), with the leaders of individual sections presenting achieved milestones, scientific results, and team synergies over the past year. Prof. Kateřina Vávrová presented on pharmaceutical and analytical chemistry (RO1), while progress in pharmacology and toxicology (RO2) was summarized by Prof. František Štaud. Prof. Martin Hrubý presented results in the field of novel drug delivery systems and formulations (RO3), and Assoc. Prof. Daniela Fialová (RO4) introduced research in geriatric clinical pharmacy focused on systematic literature reviews, algorithms for individualized pharmacotherapy, and pilot deprescribing interventions. Evaluation of activities in advanced in vitro and in silico approaches in drug development (RO5) was presented by Assoc. Prof. Tomáš Smutný. Among the keynote speakers were, for example, Prof. Martin Hrubý with a lecture on stimuli-responsive polymers for biomedical applications, and Prof. František Švec, who addressed the use of monoliths in supercritical fluid chromatography for the separation of large biologically active molecules.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Mgr_Martina_Kopecka_Jurcekova_2_vyrocni_mezinarodni_konference_NETPHARM_prof_Frantisek_Svec_0b7cb8a321.jpg" alt="Mgr. Martina Kopecká Jurčeková: Prof. František Švec" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Mgr_Martina_Kopecka_Jurcekova_2_vyrocni_mezinarodni_konference_NETPHARM_prof_Frantisek_Svec_0b7cb8a321.jpg 234w," sizes="100vw" width="1200" height="800">A key contribution was the participation of members of the International Scientific Advisory Board (ISAB), led by Prof. Maria da Conceição from the University of Porto. As part of invited lectures, these distinguished experts presented the latest global trends: Prof. Kevin A. Schug (<a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/301">University of Texas at Arlington</a>) focused on the characterization of advanced drug formulations, Prof. Igor Lacík (Slovak Academy of Sciences) discussed the use of polymers in diabetes treatment, Prof. Søren Bak (University of Copenhagen) presented plant natural products as next-generation biopesticides, and Prof. Michael Lämmerhofer (University of Tübingen) analyzed the importance of metabolomics and lipidomics in biomedical research.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Mgr_Martina_Kopecka_Jurcekova_prof_Kevin_A_Schug_b31db2c431.jpg" alt="Mgr. Martina Kopecká Jurčeková: Prof. Kevin A. Schug" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Mgr_Martina_Kopecka_Jurcekova_prof_Kevin_A_Schug_b31db2c431.jpg 234w," sizes="100vw" width="1200" height="800"><h4>Key results: 110 publications and investment in infrastructure</h4>The NETPHARM project, funded by the Jan Amos Komenský Operational Programme (OP JAK), achieved significant milestones by early 2026:<ul><li>Interdisciplinary expert team: More than 200 researchers, both experienced and early-career scientists, have been involved in research activities within the project.</li><li>Publications: 110 scientific publications have been produced, the majority of which fall into the Q1 category.</li><li>Dissemination and outreach: The number of contributions at international conferences (195) already exceeds the original plan by 38%.</li><li>Infrastructure: 16 state-of-the-art instruments have been acquired for research laboratories, with a total value of CZK 37.5 million, including an X-ray diffractometer, confocal microscopy, and a computational server.</li><li>Audit: An on-site inspection by the Ministry of Education, Youth and Sports was successfully completed, confirming the efficient use of grant funds.</li></ul><h4>Strategic recommendations for the future</h4>The conference was followed on 17 April by the 3rd meeting of the ISAB, held in the historic premises of the Carolinum in Prague. The ISAB appreciated the dynamic collaboration among institutions such as Charles University (Faculty of Pharmacy and Faculty of Medicine in Hradec Králové), the <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/11">University of Chemistry and Technology in Prague</a>, institutes of the <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/10">Czech Academy of Sciences</a> (<a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/62">IOCB Prague</a> and IMC), and <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/12">Masaryk University</a>/<a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/36">CEITEC</a>. For the remaining half of the project, experts recommended an even stronger focus on international mobility of project teams, strengthening synergies among individual teams, accelerating the patent application process, and focusing on the soft skills of junior researchers.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Mgr_Martina_Kopecka_Jurcekova_3_zasedani_rady_ISAB_0121b9b78d.jpg" alt="Mgr. Martina Kopecká Jurčeková: 3rd meeting of the ISAB" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Mgr_Martina_Kopecka_Jurcekova_3_zasedani_rady_ISAB_0121b9b78d.jpg 208w," sizes="100vw" width="1200" height="900"><h4>Networking and support for talent</h4>In addition to the intensive scientific programme, there was also a social programme, including a tour of Kudowa-Zdrój and a joint dinner. An important part was the award for the best poster presentations by young scientists, highlighting the project’s emphasis on educating a new generation of pharmaceutical experts. Among the awardees were Ing. Anna Tvrdá, Mgr. Mária Bajnoková, and Mary Angelia Alfred, M.Sc.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Mgr_Martina_Kopecka_Jurcekova_oceneni_nejlepsich_posterovych_prezentaci_37ba838bed.jpg" alt="Mgr. Martina Kopecká Jurčeková: Award for the best poster presentations" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Mgr_Martina_Kopecka_Jurcekova_oceneni_nejlepsich_posterovych_prezentaci_37ba838bed.jpg 234w," sizes="100vw" width="1200" height="800"><blockquote>“NETPHARM is at the midpoint of its journey and clearly demonstrates that building a nationwide platform of excellence makes sense. Our scientific outputs and modernized facilities form a strong foundation for innovations that will directly influence the quality of pharmaceutical care in the future,” said Prof. Petr Pávek, the project’s principal investigator, summarising the meeting.</blockquote>

2nd Annual International NETPHARM Conference

High-performance liquid chromatography (HPLC) remains one of the most widely used analytical techniques for separating, identifying, and quantifying compounds in complex mixtures. Successful HPLC method development depends not only on selecting the correct column and optimizing the mobile phase composition, but also on choosing the appropriate detector. Even a perfectly optimized chromatographic separation provides little value if the detection system cannot properly capture and interpret the analytes of interest.In many ways, the detector acts as the “vision system” of the chromatograph. It converts separated compounds into measurable electronic signals, allowing analysts to identify components and determine their concentrations. The choice of detector therefore has a major impact on sensitivity, selectivity, robustness, and the overall quality of analytical data.This article provides an overview of the most common HPLC detection techniques, discusses their strengths and limitations, and outlines the most important criteria to consider when selecting a detector for a specific analytical task.<h3>HPLC Detection Technologies</h3>HPLC detectors are typically divided into two major categories:<ol><li>Specific detectors (solute-property detectors)</li><li>Bulk property detectors</li></ol>Specific detectors respond to a particular chemical or physical property of the analyte. Ideally, their signal is largely unaffected by changes in mobile phase composition. Common examples include UV/Vis detectors, fluorescence detectors, and mass spectrometers.Bulk property detectors, on the other hand, measure differences between the pure mobile phase and the mobile phase containing analytes. These detectors are considered more universal because they respond to properties shared by many compounds. Refractive index detectors are among the best-known examples, alongside conductivity and light-scattering detectors.Both detector categories have important advantages depending on the application, sample type, and analytical goals.<h3>Common Detector Types Used in HPLC</h3>A wide variety of detectors are available for HPLC systems, ranging from highly universal devices to extremely selective and sensitive technologies.Common detector options include:<ul><li>UV/Vis detectors</li><li>Diode array detectors (DAD/PDA)</li><li>Fluorescence detectors</li><li>Refractive index detectors (RID)</li><li>Conductivity detectors</li><li>Evaporative light scattering detectors (ELSD)</li><li>Charged aerosol detectors (CAD)</li><li>Mass spectrometry detectors (MS)</li></ul>Each technology offers a different balance of sensitivity, selectivity, robustness, operational complexity, and cost.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_Detector_overview_with_characteristics_Graphic_by_KNAUER_84b0dd30b1.jpg" alt="KNAUER: Detector overview with characteristics. Graphic by KNAUER." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_Detector_overview_with_characteristics_Graphic_by_KNAUER_84b0dd30b1.jpg 245w," sizes="100vw" width="1293" height="596"><h3>Selecting the Right HPLC Detector</h3>There is no universally ideal detector for all HPLC applications. The best choice depends on several factors, including analyte chemistry, matrix complexity, required detection limits, and instrument compatibility.Careful detector selection is essential for obtaining reliable and meaningful analytical results.The following considerations can help guide the selection process.<h4>1. Chemical and Physical Properties of the Analytes</h4>The chemical nature of the compounds being analyzed is one of the most important selection criteria.Questions to consider include:<ul><li>Do the analytes contain chromophores?</li><li>Are the compounds naturally fluorescent?</li><li>What is their polarity?</li><li>What is their molecular weight?</li><li>Are they volatile or non-volatile?</li></ul>Compounds containing UV-active groups are often well suited for UV/Vis detection, while fluorescent molecules can benefit from the high sensitivity of fluorescence detectors. Non-UV-active compounds may require universal detection approaches such as CAD, ELSD, or mass spectrometry.<h4>2. Required Sensitivity</h4>Detector sensitivity determines the minimum concentration that can be reliably detected and quantified.Routine quality control analyses often rely on UV/Vis detectors because they provide sufficient sensitivity for many applications while remaining relatively simple and cost-effective. However, trace-level analysis or highly complex matrices may require more advanced technologies such as:<ul><li>Fluorescence detection</li><li>Charged aerosol detection</li><li>Mass spectrometry</li></ul>These techniques offer significantly lower detection limits and greater analytical specificity.<h4>3. Detector Linearity</h4>Linearity describes how well detector response correlates with analyte concentration across a defined range.A detector with strong linearity ensures accurate quantification and simplifies calibration procedures. Poor linearity can introduce quantification errors, especially when analyzing samples across broad concentration ranges.<h4>4. Dynamic Range</h4>Dynamic range refers to the concentration interval over which the detector can reliably measure analytes.Applications involving samples with highly variable concentrations require detectors capable of maintaining accurate response over a broad range. A wide dynamic range reduces the need for repeated dilutions or multiple analytical runs.<h4>5. Selectivity</h4>Selectivity defines the detector’s ability to distinguish target analytes from other matrix components.This factor becomes particularly important for complex samples containing many interfering substances. Highly selective detectors reduce the risk of overlapping signals and false positives.Mass spectrometry is often advantageous when dealing with unknown compounds or highly complicated sample matrices because it provides structural information in addition to quantitative data.<h4>6. Budget Considerations</h4>Detector cost is another practical factor that laboratories must evaluate.UV/Vis and refractive index detectors are generally among the more economical choices, making them attractive for routine analyses and standard applications.More sophisticated technologies such as fluorescence detection, CAD, or mass spectrometry typically require:<ul><li>Higher initial investment</li><li>Additional maintenance</li><li>More complex infrastructure</li><li>Greater operational expertise</li></ul>However, the overall value of the detector should always be considered in relation to analytical performance requirements and long-term application needs.<h4>7. Instrument and Mobile Phase Compatibility</h4>The selected detector must be compatible with the operational conditions of the HPLC system.Important parameters include:<ul><li>Flow rate range</li><li>Pressure limitations</li><li>Mobile phase composition</li><li>Solvent compatibility</li></ul>Some detectors are highly sensitive to mobile phase composition or gradient changes, while others tolerate a broader range of operating conditions.Ensuring proper compatibility helps prevent baseline instability, signal interference, and reduced detector performance.<h4>8. Destructive vs. Non-Destructive Detection</h4>Another important consideration is whether the analytical workflow involves only detection or also preparative purification.Non-destructive detectors allow collected fractions to remain intact after detection, which is highly beneficial for preparative chromatography and purification workflows.Destructive detectors, by contrast, consume or alter the sample during measurement and are therefore more suitable for analytical applications where sample recovery is not required.<h4>9. Reliability and Ease of Operation</h4>Practical usability is often just as important as analytical performance.Some detectors are designed for straightforward plug-and-play operation, while others require:<ul><li>Frequent calibration</li><li>Specialized maintenance</li><li>Dedicated gas supplies</li><li>Vacuum systems</li><li>Advanced operator expertise</li></ul>Laboratories should evaluate the available technical support, user experience, and maintenance capabilities before implementing more sophisticated detection technologies.Reliable operation and manageable maintenance requirements can significantly improve laboratory productivity and reduce downtime.Choosing the correct HPLC detector starts with understanding both the sample and the analytical objective. Rather than selecting a detector simply because it is available, laboratories should ensure that the technology aligns with the chemistry of the analytes, required performance characteristics, and workflow demands.In many cases, combining multiple detectors within a single HPLC system can provide even greater analytical insight by delivering complementary information from the same chromatographic separation.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_Flow_scheme_for_detector_selection_Graphic_by_KNAUER_486004045f.jpg" alt="KNAUER: Flow scheme for detector selection. Graphic by KNAUER." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_Flow_scheme_for_detector_selection_Graphic_by_KNAUER_486004045f.jpg 245w," sizes="100vw" width="1316" height="808">Interested in learning more? Future articles will explore individual HPLC detection techniques in greater detail, including their operating principles, application areas, and practical advantages for different analytical workflows.

A comprehensive guide for selecting the appropriate HPLC detector

News from LabRulezLCMS Library - Week 20, 2026

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Academy

Science and research

The Faculty of Pharmacy, with its seat in the town of Hradec Králové, was established by a government decree in 1969. This Faculty of Pharmacy has continued in the old and long-time tradition of the education of pharmacy at Charles University.

Faculty of Pharmacy, Charles University

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Based in Berlin, KNAUER is a medium-sized, owner-managed company that has been serving the sciences since 1962. We develop and manufacture scientific instruments of superior quality for liquid chromatography, including: Analytical HPLC/UHPLC, Preparative HPLC, Fast protein liquid chromatography (FPLC), Multi-column chromatography/Simulated moving bed (SMB) chromatography. High pressure dosing, in-line detection systems, and osmometry are additional business areas.

KNAUER

Watrex P280 HPLC Pump Prep, stainless steel

Explore the future of preparative chromatography with PrecisionPrep™ P280, a state-of-the-art pump that redefines efficiency and precision.

Explore the future of preparative chromatography with PrecisionPrep™ P280, a state-of-the-art pump that redefines efficiency and precision.<blockquote>Price: 4 985<bdi>&nbsp;€ ex VAT</bdi></blockquote>Featuring a unique parallel double-piston arrangement, this preparative chromatography pump is designed to meet the demands of high-flow applications while ensuring a stable and precise flow profile.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Watrex_P280_HPLC_Pump_Prep_stainless_steel_b864d583c2.jpg" alt="Watrex P280 HPLC Pump Prep, stainless steel.jpg" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Watrex_P280_HPLC_Pump_Prep_stainless_steel_b864d583c2.jpg 235w," sizes="100vw" width="1024" height="681"><h3>PUMP FEATURES</h3><h5>Parallel Double-Piston Arrangement:</h5><ul><li>The innovative dual-piston design allows for parallel operation, optimizing flow distribution and enhancing efficiency.</li><li>Experience enhanced performance and productivity in preparative chromatography with this cutting-edge arrangement.</li><li>Achieve unmatched versatility with flow rates reaching up to 80 ml/min.</li><li>Tailor the pump’s performance to accommodate a wide range of preparative chromatography applications.</li></ul><h5>Stable and Precise Flow Profile:</h5><ul><li>Enjoy a stable and precise flow profile, critical for reproducibility in preparative separations.</li><li>The P280 ensures consistent and reliable results in every run, minimizing experimental variability.</li></ul><h5>User-Friendly Interface:</h5><ul><li>The user-friendly interface simplifies operation, allowing for seamless control and monitoring of preparative chromatography processes.</li><li>Easily program and adjust parameters to suit the specific requirements of your purification protocols.</li></ul><h5>Applications:</h5><ul><li>Purification of Pharmaceuticals</li><li>Isolation of Natural Products</li><li>Large-scale Biomolecule Purification</li><li>Industrial Separations/li&gt;</li></ul><h5>Reliability Beyond Measure:</h5><ul><li>PrecisionPrep™ P280 is engineered for durability and reliability in demanding preparative chromatography applications.</li><li>Trust in its robust construction and precise engineering to deliver consistent results run after run.</li></ul><h4>Conclusion</h4>Elevate your preparative chromatography to new heights with PrecisionPrep™ P280. With a parallel double-piston arrangement, high flow rates, and an efficient pulse dampener, this pump is designed to meet the challenges of large-scale separations while ensuring a stable and precise flow profile. Choose PrecisionPrep™ for unparalleled efficiency and reliability in preparative chromatography.<h3>TECHNICAL SPECIFICATION</h3><ul><li>Flow Rates: 0,1 ml/min – 80 ml/min with step 0.1 ml/min</li><li>Pressure: 5 MPa/725 psi</li><li>Flow precision: ± 0,2% RSD @ 10mL/min</li><li>Flow accuracy: ± 1% @ 10mL/min</li><li>Pressure accuracy: ± 2% of full-scale, with 80:20 H2O/IPA</li><li>Pulsation: better than ± 1% @ 10mL/min</li><li>Remote control: USB</li><li>I/O connector: Start, Stop, Status, Error</li></ul>You can also visit this product on the <a target="_blank" rel="noopener noreferrer" href="https://watrex.com/obchod/chromatography/pumps/preparative-pumps/p280-pump-prep-stainless-steel/?utm_source=labrulez&amp;utm_medium=propagace&amp;utm_campaign=labrulez_produkty">Watrex website</a>.

Watrex P280 HPLC Pump Prep, PEEK, biocompatible

Explore the future of preparative chromatography with PrecisionPrep™ P280, a state-of-the-art pump that redefines efficiency and precision.<blockquote>Price: 4 985<bdi>&nbsp;€ ex VAT</bdi></blockquote>Featuring a unique parallel double-piston arrangement, this preparative chromatography pump is designed to meet the demands of high-flow applications while ensuring a stable and precise flow profile.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Watrex_P102_HPLC_pump_PEEK_5321aceaa0.jpg" alt="Watrex P280 HPLC Pump Prep, PEEK, biocompatible" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Watrex_P102_HPLC_pump_PEEK_5321aceaa0.jpg 208w," sizes="100vw" width="1024" height="768"><h3>PUMP FEATURES</h3><h5>Parallel Double-Piston Arrangement:</h5><ul><li>The innovative dual-piston design allows for parallel operation, optimizing flow distribution and enhancing efficiency.</li><li>Experience enhanced performance and productivity in preparative chromatography with this cutting-edge arrangement.</li><li>Achieve unmatched versatility with flow rates reaching up to 80 ml/min.</li><li>Tailor the pump’s performance to accommodate a wide range of preparative chromatography applications.</li></ul><h5>Stable and Precise Flow Profile:</h5><ul><li>Enjoy a stable and precise flow profile, critical for reproducibility in preparative separations.</li><li>The P280 ensures consistent and reliable results in every run, minimizing experimental variability.</li></ul><h5>User-Friendly Interface:</h5><ul><li>The user-friendly interface simplifies operation, allowing for seamless control and monitoring of preparative chromatography processes.</li><li>Easily program and adjust parameters to suit the specific requirements of your purification protocols.</li></ul><h5>Applications:</h5><ul><li>Purification of Pharmaceuticals</li><li>Isolation of Natural Products</li><li>Large-scale Biomolecule Purification</li><li>Industrial Separations/li&gt;</li></ul><h5>Reliability Beyond Measure:</h5><ul><li>PrecisionPrep™ P280 is engineered for durability and reliability in demanding preparative chromatography applications.</li><li>Trust in its robust construction and precise engineering to deliver consistent results run after run.</li></ul><h4>Conclusion</h4>Elevate your preparative chromatography to new heights with PrecisionPrep™ P280. With a parallel double-piston arrangement, high flow rates, and an efficient pulse dampener, this pump is designed to meet the challenges of large-scale separations while ensuring a stable and precise flow profile. Choose PrecisionPrep™ for unparalleled efficiency and reliability in preparative chromatography.<h3>TECHNICAL SPECIFICATION</h3><ul><li>Flow Rates: 0,1 ml/min – 80 ml/min with step 0.1 ml/min</li><li>Pressure: 5 MPa/725 psi</li><li>Flow precision: ± 0,2% RSD @ 10mL/min</li><li>Flow accuracy: ± 1% @ 10mL/min</li><li>Pressure accuracy: ± 2% of full-scale, with 80:20 H2O/IPA</li><li>Pulsation: better than ± 1% @ 10mL/min</li><li>Remote control: USB</li><li>I/O connector: Start, Stop, Status, Error</li></ul>You can also visit this product on the <a target="_blank" rel="noopener noreferrer" href="https://watrex.com/obchod/chromatography/pumps/preparative-pumps/p280-pump-prep-peek-biocompatible/?utm_source=labrulez&amp;utm_medium=propagace&amp;utm_campaign=labrulez_produkty">Watrex website</a>.

Watrex P224 HPLC Pump, dual head, PEEK, biocompatible

WATREX P224 semiprep chromatography pump is a versatile and reliable tool commonly employed in laboratory settings, particularly in applications requiring precise dosing.

WATREX P224 semiprep chromatography pump is a versatile and reliable tool commonly employed in laboratory settings, particularly in applications requiring precise dosing.<blockquote>Price: 4 985<bdi>&nbsp;€ ex VAT</bdi></blockquote>This pump is designed for semipreparative chromatography, which involves the separation and purification of compounds at a larger scale than analytical chromatography but smaller than preparative chromatography. The stainless steel version of the pump offers durability and chemical resistance, making it suitable for use with a wide range of solvents and samples.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Watrex_P102_HPLC_pump_PEEK_5321aceaa0.jpg" alt="Watrex: P224 HPLC Pump, dual head, PEEK, biocompatible" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Watrex_P102_HPLC_pump_PEEK_5321aceaa0.jpg 208w," sizes="100vw" width="1024" height="768"><h3>PUMP FEATURES</h3><ul><li>Flow Rate Control: P224 allows for precise control of flow rates, crucial for achieving accurate and reproducible results in chromatographic separations.</li><li>Pressure Control: P224 has a built-in pressure control system to maintain consistent pressure throughout the chromatographic process, ensuring optimal column performance.</li><li>Gradient Capability: Two or up to four P224 pumps offer gradient capabilities, allowing for the creation of complex elution profiles controlled from PC to enhance separation efficiency.</li><li>User-Friendly Interface: An intuitive and user-friendly interface facilitates easy operating and monitoring of the pump parameters, contributing to efficient workflow in the laboratory.</li><li>Compatibility: P224 is compatible with a variety of chromatography instruments and stationary phases commonly used in semipreparative applications.</li><li>Reliability and Durability: A robust construction and high-quality materials ensure the pump’s durability and reliability, minimizing downtime and maintenance requirements.</li><li>Precision in Dosing: P224 design prioritizes accuracy in dosing, making it suitable for applications where precise control over sample injection and elution volumes is essential.</li><li>Safety Features: Incorporation of safety features such as pressure sensors, and overpressure protection ensures the well-being of both the operator and the equipment.</li><li>Maintenance and Calibration: P224 pumps are easy to maintain and calibrate, with clear documentation provided by us for routine upkeep and troubleshooting.</li><li>Versatility: P224 supports a wide range of solvents and mobile phases commonly used in chromatography, offering flexibility for various applications.</li><li>Data Logging and Connectivity: The capability to log service data enhances operation traceability and documentation.</li></ul><h3>TECHNICAL SPECIFICATION</h3><ul><li>Flow Rates: 0,1 ml/min – 25,00 ml/min with step 0.1 ml/min (semiprep)</li><li>Pressure: 30 MPa/4300 psi</li><li>Flow precision: &nbsp;&nbsp;&nbsp;&nbsp;± 0,2% RSD @ 1mL/min. and 7 Mpa</li><li>Flow accuracy: ± 1% @ 1mL/min. and 7 Mpa</li><li>Pressure accuracy: ± 2% of full-scale, with 80:20 H2O/IPA @ 7 Mpa</li><li>Pulsation: better than ± 0.5% @ 1mL/min. and 7 MPa</li><li>Remote control: USB</li><li>I/O connector: Start, Stop, Status, Error</li></ul>You can also visit this product on the <a target="_blank" rel="noopener noreferrer" href="https://watrex.com/obchod/chromatography/pumps/preparative-pumps/p224-pump-dual-head-peek-biocompatible/?utm_source=labrulez&amp;utm_medium=propagace&amp;utm_campaign=labrulez_produkty">Watrex website</a>.

Watrex P224 HPLC Pump, dual head, Stainless Steel

WATREX P224 semiprep chromatography pump is a versatile and reliable tool commonly employed in laboratory settings, particularly in applications requiring precise dosing.<blockquote>Price: 4 985<bdi>&nbsp;€ ex VAT</bdi></blockquote>This pump is designed for semipreparative chromatography, which involves the separation and purification of compounds at a larger scale than analytical chromatography but smaller than preparative chromatography. The stainless steel version of the pump offers durability and chemical resistance, making it suitable for use with a wide range of solvents and samples.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Watrex_P280_HPLC_Pump_Prep_stainless_steel_b864d583c2.jpg" alt="Watrex: P224 HPLC Pump, dual head, Stainless Steel" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Watrex_P280_HPLC_Pump_Prep_stainless_steel_b864d583c2.jpg 235w," sizes="100vw" width="1024" height="681"><h3>PUMP FEATURES</h3><ul><li>Flow Rate Control: P224 allows for precise control of flow rates, crucial for achieving accurate and reproducible results in chromatographic separations.</li><li>Pressure Control: P224 has a built-in pressure control system to maintain consistent pressure throughout the chromatographic process, ensuring optimal column performance.</li><li>Gradient Capability: Two or up to four P224 pumps offer gradient capabilities, allowing for the creation of complex elution profiles controlled from PC to enhance separation efficiency.</li><li>User-Friendly Interface: An intuitive and user-friendly interface facilitates easy operating and monitoring of the pump parameters, contributing to efficient workflow in the laboratory.</li><li>Compatibility: P224 is compatible with a variety of chromatography instruments and stationary phases commonly used in semipreparative applications.</li><li>Reliability and Durability: A robust construction and high-quality materials ensure the pump’s durability and reliability, minimizing downtime and maintenance requirements.</li><li>Precision in Dosing: P224 design prioritizes accuracy in dosing, making it suitable for applications where precise control over sample injection and elution volumes is essential.</li><li>Safety Features: Incorporation of safety features such as pressure sensors, and overpressure protection ensures the well-being of both the operator and the equipment.</li><li>Maintenance and Calibration: P224 pumps are easy to maintain and calibrate, with clear documentation provided by us for routine upkeep and troubleshooting.</li><li>Versatility: P224 supports a wide range of solvents and mobile phases commonly used in chromatography, offering flexibility for various applications.</li><li>Data Logging and Connectivity: The capability to log service data enhances operation traceability and documentation.</li></ul><h3>TECHNICAL SPECIFICATION</h3><ul><li>Flow Rates: 0,1 ml/min – 25,00 ml/min with step 0.1 ml/min (semiprep)</li><li>Pressure: 30 MPa/4300 psi</li><li>Flow precision: &nbsp;&nbsp;&nbsp;&nbsp;± 0,2% RSD @ 1mL/min. and 7 Mpa</li><li>Flow accuracy: ± 1% @ 1mL/min. and 7 Mpa</li><li>Pressure accuracy: ± 2% of full-scale, with 80:20 H2O/IPA @ 7 Mpa</li><li>Pulsation: better than ± 0.5% @ 1mL/min. and 7 MPa</li><li>Remote control: USB</li><li>I/O connector: Start, Stop, Status, Error</li></ul>You can also visit this product on the <a target="_blank" rel="noopener noreferrer" href="https://watrex.com/obchod/chromatography/pumps/preparative-pumps/p224-pump-dual-head-stainless-steel/?utm_source=labrulez&amp;utm_medium=propagace&amp;utm_campaign=labrulez_produkty">Watrex website</a>.

KNAUER AZURA® Compact Prep HPLC System

The AZURA® Prep Compact system is the perfect start into preparative chromatography. With the complete, semi-preparative HPLC system you master your isocratic purification tasks.

AZURA® Preparative HPLC Customized purificationAZURA® preparative systems are the perfect solution for frequently changing separation tasks – from milligram to kilogram scale. Design your AZURA preparative system to your needs and combine flexibility and reliability.<h5>Customaze your system</h5>AZURA® Prep systems are tailor-made for you. Configure your system from injection to detection and choose between different materials, flow rates, valves, and detectors.<h5>Easy scale up from compact to pilot systems</h5>Due to the flexible design of our devices, you can easily change parts like pump heads or flow cells and integrate all components of the compact into the pilot-scale system.<h5>Stacked injections, peak &amp; solvent recycling</h5>AZURA® Prep systems can be used for special separation modes like peak recycling and stacked injections. We help you to configure your system and choose the best software for you.<h3>Flexibility and performance</h3><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_AZURA_Prep_HPLC_System_90fef641c3.jpg" alt="KNAUER AZURA® Prep HPLC System." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_AZURA_Prep_HPLC_System_90fef641c3.jpg 245w," sizes="100vw" width="1920" height="1059"><h2>AZURA® Compact Prep HPLC System</h2>The AZURA® Prep Compact system is the perfect start into preparative chromatography. With the complete, semi-preparative HPLC system you master your isocratic purification tasks.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_AZURA_Compact_Prep_HPLC_System_3_863a93178e.jpg" alt="KNAUER: AZURA® Compact Prep HPLC System." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_AZURA_Compact_Prep_HPLC_System_3_863a93178e.jpg 245w," sizes="100vw" width="1590" height="604"><h4>Compact Prep System</h4>One manual injection can purify several hundred milligrams at up to 50 ml/min. Detection takes place via a versatile UV/VIS detector. The intuitive preparative software PurityChrom controls the compact system and regulates the fraction collection via a 12-port fractionating valve. Thanks to its compact design, the AZURA Prep Compact system finds its place in every laboratory.<img style="aspect-ratio:1024/742;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_AZURA_Compact_Prep_HPLC_System_48291f6f6e.webp" alt="KNAUER: AZURA® Compact Prep HPLC System." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_AZURA_Compact_Prep_HPLC_System_48291f6f6e.webp 215w," sizes="100vw" width="1024" height="742"><ul><li>Up to 150 bar</li><li>Complete semi-preparative isocratic HPLC system with low space requirements</li><li>Up to 10 ml injection volumes &nbsp;</li><li>Injection valve incl. 500 μl sample loop&nbsp;</li><li>Collect up to 16 large fractions</li><li>Columns from 4–20 mm ID</li><li>UV/VIS detector with one variable wavelength</li><li>Intuitive PurityChrom®, MobileControl® software</li><li>Compact and expandable</li></ul><h3>Easy upgrade without big investment</h3><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_AZURA_Compact_Prep_HPLC_System_4_efed81c462.jpg" alt="KNAUER: AZURA® Compact Prep HPLC System: Easy upgrade without big investment." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_AZURA_Compact_Prep_HPLC_System_4_efed81c462.jpg 245w," sizes="100vw" width="1600" height="761"><h4>Pilot Prep System</h4><div><div data-message-author-role="assistant" data-message-id="efe48b67-eccf-4ebf-8484-ea6d1f96ed57" dir="auto" data-message-model-slug="gpt-4o"><div><div>After starting preparative chromatography with the space-saving prep system, the requirements for your purification tasks can quickly increase. The existing Compact System (50 ml/min) can be expanded to a Pilot System (220 ml/min) by investing in a fraction collector and a preparative pump. All components of the Compact System are fully integrated into the Pilot System.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_AZURA_Compact_Prep_HPLC_System_2_d713ad0086.jpg" alt="KNAUER: AZURA® Compact Prep HPLC System: Easy upgrade without big investment." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_AZURA_Compact_Prep_HPLC_System_2_d713ad0086.jpg 178w," sizes="100vw" width="1606" height="1407"><ul><li>Pilot Ternary gradient HPLC system with injection valve incl. 500 μl sample loop&nbsp;</li><li>Sample pump with automatic sample selection&nbsp;</li><li>UV/VIS detector&nbsp;with one variable wavelength</li><li>Intuitive PurityChrom® software</li><li>Fraction collector</li></ul></div></div></div></div>

KNAUER AZURA® Bio Compact AC FPLC System

The AZURA Compact AC system qualifies for fast and reliable affinity chromatography. 

KNAUER protein purification: The flexible FPLC platformAZURA® Bio purification systems&nbsp;complete solutions for FPLC on a minimum footprint: AZURA FPLC systems combine flexibility and reliability. The biocompatible/metal-free FPLC is the perfect choice for your protein purification task.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_AZURA_Bio_Compact_AC_FPLC_System_6_a874551078.jpg" alt="KNAUER: AZURA® Bio Compact AC FPLC System." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_AZURA_Bio_Compact_AC_FPLC_System_6_a874551078.jpg 245w," sizes="100vw" width="1506" height="600">Design your AZURA Bio purification system to fit your needs. Multiple functionalities such as automatic sample injection via autosampler, column switching, buffer and sample selection, and fraction collection enable automation of the purification process.A wide range of detectors ensures the visibility of target molecules. Various flow rates and compatibility with columns from all vendors provide maximum flexibility. The intuitive PurityChrom® software integrates all the advantages of a versatile purification system.<h3>AZURA® Bio Compact AC FPLC System</h3><h4>For affinity chromatography</h4>The AZURA Compact AC system qualifies for fast and reliable affinity chromatography. Select your sample, washing, and elution buffer using the selection valve. Your proteins of interest are detected by UV and automatically collected via the fractionation valve.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_AZURA_Bio_Compact_AC_FPLC_System_4_bef2309e7d.jpg" alt="KNAUER: AZURA® Bio Compact AC FPLC System." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_AZURA_Bio_Compact_AC_FPLC_System_4_bef2309e7d.jpg 245w," sizes="100vw" width="1666" height="513"><h3>Key features</h3><ul><li data-start="93" data-end="153">Flow rate: 0.01–50 ml/min (recommended: 1–40 ml/min)</li><li data-start="154" data-end="193">Maximum system pressure: 50 bar</li><li data-start="194" data-end="278">Sample and buffer selection: Automatic valve for up to 12 buffers or samples</li><li data-start="279" data-end="349">Detection: Variable single wavelength UV detector (190–500 nm)</li><li data-start="350" data-end="429">Column compatibility: Compatible with affinity columns from all vendors</li><li data-start="430" data-end="574">Fraction collection: 16-port fractionation valve, capable of collecting up to 16 fractions for flow-through, wash, and elution fractions</li><li data-start="575" data-end="663">Software: Intuitive and powerful PurityChrom® software, 21 CFR Part 11 compliant</li><li data-start="664" data-end="737">Affinity purification: Designed for tagged proteins or antibodies</li><li data-start="738" data-end="867">Compact system: User-friendly and cost-efficient, with the ability to upgrade for more complex protein purification tasks</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_AZURA_Bio_Compact_AC_FPLC_System_5_17f4f13731.jpg" alt="KNAUER AZURA® Bio Compact AC FPLC System: Protein purification based on high affinity Chromatogram &amp; Legend." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_AZURA_Bio_Compact_AC_FPLC_System_5_17f4f13731.jpg 209w," sizes="100vw" width="1024" height="766">&nbsp;

KNAUER AZURA® Bio Compact SEC FPLC System

AZURA Compact SEC systems handle time-consuming SEC methods in your lab without occupying your valuable FPLC system.

KNAUER protein purification: The flexible FPLC platformAZURA® Bio purification systems&nbsp;complete solutions for FPLC on a minimum footprint: AZURA FPLC systems combine flexibility and reliability. The biocompatible/metal-free FPLC is the perfect choice for your protein purification task.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_AZURA_Bio_Compact_AC_FPLC_System_6_a874551078.jpg" alt="KNAUER: AZURA® Bio Compact AC FPLC System." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_AZURA_Bio_Compact_AC_FPLC_System_6_a874551078.jpg 245w," sizes="100vw" width="1506" height="600">Design your AZURA Bio purification system to fit your needs. Multiple functionalities such as automatic sample injection via autosampler, column switching, buffer and sample selection, and fraction collection enable automation of the purification process.A wide range of detectors ensures the visibility of target molecules. Various flow rates and compatibility with columns from all vendors provide maximum flexibility. The intuitive PurityChrom® software integrates all the advantages of a versatile purification system.<h3>AZURA® Bio Compact SEC FPLC System</h3><h4>For Size Exclusion Chromatography (SEC)</h4>AZURA Compact SEC systems take over time-consuming SEC methods in your lab without blocking your valuable FPLC system. Due to its compact design and intuitive FPLC software PurityChrom®, the system offers outstanding performance and ease of use.&nbsp;Pre-designed methods are included in the software for the designated SEC system and can be easily adapted by changing the column volume. AZURA Compact SEC supports all columns available on the market.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_AZURA_Bio_Compact_SEC_FPLC_System_4_f5efb08061.jpg" alt="KNAUER: AZURA® Bio Compact SEC FPLC System " srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_AZURA_Bio_Compact_SEC_FPLC_System_4_f5efb08061.jpg 245w," sizes="100vw" width="1358" height="540"><h3>Key features</h3><ul><li data-start="93" data-end="157">Flow rate: 0.001–10 ml/min (recommended: 0.1–8.0 ml/min)</li><li data-start="158" data-end="197">Maximum system pressure: 50 bar</li><li data-start="198" data-end="276">Injection system: Injection valve for sample injection via sample loop</li><li data-start="277" data-end="347">Detection: Variable single wavelength UV detector (190–500 nm)</li><li data-start="348" data-end="423">Fraction collection: Fraction collector for automated fractionation</li><li data-start="424" data-end="522">Column compatibility: Supports columns from all vendors, including third-party SEC columns</li><li data-start="523" data-end="611">Software: Intuitive and powerful PurityChrom® software, 21 CFR Part 11 compliant</li><li data-start="612" data-end="780">System design:<ul data-start="637" data-end="780"><li data-start="637" data-end="666">Isocratic buffer delivery</li><li data-start="669" data-end="687">Loop injection</li><li data-start="690" data-end="734">Wide range of collection racks available</li><li data-start="737" data-end="780">Specially designed for SEC applications</li></ul></li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_AZURA_Bio_Compact_SEC_FPLC_System_3_7a4bc1f60b.jpg" alt="KNAUER: AZURA® Bio Compact SEC FPLC System " srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_AZURA_Bio_Compact_SEC_FPLC_System_3_7a4bc1f60b.jpg 245w," sizes="100vw" width="1920" height="1152">Don't use your valuable gradient FPLC system for boring and time-consuming size exclusion separations. Choose your dedicated AZURA SEC system.<figure class="image"><img style="aspect-ratio:690/490;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_AZURA_Bio_Compact_SEC_FPLC_System_45d5079064.webp" alt="KNAUER: AZURA® Bio Compact SEC FPLC System." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_AZURA_Bio_Compact_SEC_FPLC_System_45d5079064.webp 220w," sizes="100vw" width="690" height="490"></figure>With its compact design and intuitive software, the system offers excellent performance, ease of use and supports all SEC columns available on the market.​

KNAUER AZURA® Bio Lab FPLC System

AZURA Bio Lab allows you to create FPLC systems with highest independence. Just pick your modules and build-up the system yourself. The intuitive software PurityChrom will be flexibly adjusted to your system.

KNAUER protein purification: The flexible FPLC platformAZURA® Bio purification systems&nbsp;complete solutions for FPLC on a minimum footprint: AZURA FPLC systems combine flexibility and reliability. The biocompatible/metal-free FPLC is the perfect choice for your protein purification task.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_AZURA_Bio_Compact_AC_FPLC_System_6_a874551078.jpg" alt="KNAUER: AZURA® Bio Compact AC FPLC System." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_AZURA_Bio_Compact_AC_FPLC_System_6_a874551078.jpg 245w," sizes="100vw" width="1506" height="600">Design your AZURA Bio purification system to fit your needs. Multiple functionalities such as automatic sample injection via autosampler, column switching, buffer and sample selection, and fraction collection enable automation of the purification process.A wide range of detectors ensures the visibility of target molecules. Various flow rates and compatibility with columns from all vendors provide maximum flexibility. The intuitive PurityChrom® software integrates all the advantages of a versatile purification system.<h3>AZURA® Bio Lab FPLC System</h3><h4>R&amp;D-scale gradient system for complex purifications of bio molecules</h4>AZURA Bio Lab allows you to create FPLC systems with highest independence. Just pick your modules and build-up the system yourself. The intuitive software PurityChrom will be flexibly adjusted to your system.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_AZURA_Bio_Lab_FPLC_System_3_7b22a3e099.jpg" alt="KNAUER: AZURA® Bio Lab FPLC System." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_AZURA_Bio_Lab_FPLC_System_3_7b22a3e099.jpg 245w," sizes="100vw" width="1645" height="671"><h3>Key features</h3><ul><li data-start="93" data-end="145">Flow rate: 0.001–50 ml/min (maximum 240 bar)</li><li data-start="146" data-end="224">Injection system: Sample injections via sample loop and/or sample pump</li><li data-start="225" data-end="295">Detection: Variable single wavelength UV detector (190–500 nm)</li><li data-start="296" data-end="386">Fraction collection: XY fraction collector for large volumes or numerous fractions</li><li data-start="387" data-end="493">Column compatibility: Supports up to 7 columns for method development – all FPLC columns supported</li><li data-start="494" data-end="584">Suitable for Ion-exchange, HILIC, affinity, SEC, and RP</li><li data-start="585" data-end="640">Reproducible and automated protein purification</li><li data-start="641" data-end="695">System usability: Suitable for cold room usage</li><li data-start="696" data-end="820">Software:<ul data-start="716" data-end="820"><li data-start="716" data-end="780">Intuitive and powerful PurityChrom® software (basic license)</li><li data-start="783" data-end="820">21 CFR Part 11 compliant software</li></ul></li><li data-start="821" data-end="924">Additional features:<ul data-start="852" data-end="924"><li data-start="852" data-end="924">Conductivity and pH-monitoring, pressure, and air sensors (optional)</li></ul></li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_AZURA_Bio_Lab_FPLC_System_4740938659.jpg" alt="KNAUER: AZURA® Bio Lab FPLC System." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_AZURA_Bio_Lab_FPLC_System_4740938659.jpg 235w," sizes="100vw" width="1920" height="1279">From simple to advanced, from lab to process scale – configure your FPLC with our modular design according to your purification needs.Designed and optimized for all FPLC applications such as affinity, ion exchange, hydrophobic interaction and size exclusion chromatography. All system modules can be expanded with additional modules.

KNAUER AZURA® Bio Lab Advanced FPLC System

Gradient-capable FPLC system for a wide range of purifications including automated two-step applications

KNAUER protein purification: The flexible FPLC platformAZURA® Bio purification systems&nbsp;complete solutions for FPLC on a minimum footprint: AZURA FPLC systems combine flexibility and reliability. The biocompatible/metal-free FPLC is the perfect choice for your protein purification task.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_AZURA_Bio_Compact_AC_FPLC_System_6_a874551078.jpg" alt="KNAUER: AZURA® Bio Compact AC FPLC System." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_AZURA_Bio_Compact_AC_FPLC_System_6_a874551078.jpg 245w," sizes="100vw" width="1506" height="600">Design your AZURA Bio purification system to fit your needs. Multiple functionalities such as automatic sample injection via autosampler, column switching, buffer and sample selection, and fraction collection enable automation of the purification process.A wide range of detectors ensures the visibility of target molecules. Various flow rates and compatibility with columns from all vendors provide maximum flexibility. The intuitive PurityChrom® software integrates all the advantages of a versatile purification system.<h3>AZURA® Bio Lab Advanced FPLC System</h3><h4>Gradient-capable FPLC system for a wide range of purifications including automated two-step applications</h4>Protein purification involves most of the times two to three steps:<ol><li>capture step</li><li>optional intermediated step</li><li>polishing step</li></ol>The transition from one to another step generally involves manual interaction and thus is time-consuming. Automation by combining these steps increases the efficiency and optimizes the workflow.&nbsp;The quick and automated linkage of multiple chromatographic purification steps into one method eliminates manual sample handling and minimizes time spent between steps. This automation strategy can be easily adapted to each purification task.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_AZURA_Bio_Lab_FPLC_System_3_7b22a3e099.jpg" alt="KNAUER: AZURA® Bio Lab Advanced FPLC System." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_AZURA_Bio_Lab_FPLC_System_3_7b22a3e099.jpg 245w," sizes="100vw" width="1645" height="671"><h3>Key features</h3><ul data-start="93" data-end="1077"><li data-start="93" data-end="144">Flow rate: 0.001–50 ml/min (maximum 50 bar)</li><li data-start="145" data-end="263">Injection system: Sample injection via loop or sample pump, with automated storage and reinjection of proteins</li><li data-start="264" data-end="433">Detection system:<ul data-start="292" data-end="433"><li data-start="292" data-end="320">Multichannel UV detector</li><li data-start="323" data-end="405">Highly sensitive multi-wavelength detector for proteins, DNA/RNA, and peptides</li><li data-start="408" data-end="433">Conductivity detector</li></ul></li><li data-start="434" data-end="566">Fraction collection: XY fraction collector with outlet valve for automated collection of large volumes or numerous fractions</li><li data-start="567" data-end="673">Column compatibility: Supports up to 7 columns for method development – all FPLC columns supported</li><li data-start="674" data-end="764">Suitable for Ion-exchange, HILIC, affinity, SEC, and RP</li><li data-start="765" data-end="864">Automation: Enables challenging protein purification tasks with minimal manual intervention</li><li data-start="865" data-end="973">Software:<ul data-start="885" data-end="973"><li data-start="885" data-end="933">Intuitive and powerful PurityChrom® software</li><li data-start="936" data-end="973">21 CFR Part 11 compliant software</li></ul></li><li data-start="974" data-end="1077">Additional features:<ul data-start="1005" data-end="1077"><li data-start="1005" data-end="1077">Conductivity and pH-monitoring, pressure, and air sensors (optional)</li></ul></li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_AZURA_Bio_Lab_Advanced_FPLC_System_3_9cf517ceaf.webp" alt="KNAUER: AZURA® Bio Lab Advanced FPLC System." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_AZURA_Bio_Lab_Advanced_FPLC_System_3_9cf517ceaf.webp 234w," sizes="100vw" width="690" height="460"><h3>Two-step purification: Special multi-column chromatography solutions</h3>Designed and optimized for all FPLC applications such as affinity, ion exchange, hydrophobic interaction and size exclusion chromatography. In addition, you can perform dedicated twoSTEP applications.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_AZURA_Bio_Lab_Advanced_FPLC_System_44bff80cfc.webp" alt="KNAUER: AZURA® Bio Lab Advanced FPLC System." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_AZURA_Bio_Lab_Advanced_FPLC_System_44bff80cfc.webp 209w," sizes="100vw" width="1920" height="1434"><h3>Automated two-step purification of mouse IgG antibodies</h3><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_AZURA_Bio_Lab_Advanced_FPLC_System_4_c86d2177ce.jpg" alt="KNAUER: AZURA® Bio Lab Advanced FPLC System: The affinity chromatography step was automatically combined with a gel filtration step to exchange the buffer of the purified mouse IgG antibodies; Phase 1: Column equilibration, Phase 2: Sample injection and washing, Phase 3: Elution of IgG from protein A column, Phase 4: Desalting of IgG." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_AZURA_Bio_Lab_Advanced_FPLC_System_4_c86d2177ce.jpg 245w," sizes="100vw" width="1085" height="605">

KNAUER AZURA® Bio Lab Pilot FPLC System

Configure your FPLC system based on your purification requirements. The Pilot system is designed for scale-up and process applications. All system modules can be expanded with additional modules.

KNAUER protein purification: The flexible FPLC platformAZURA® Bio purification systems&nbsp;complete solutions for FPLC on a minimum footprint: AZURA FPLC systems combine flexibility and reliability. The biocompatible/metal-free FPLC is the perfect choice for your protein purification task.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_AZURA_Bio_Compact_AC_FPLC_System_6_a874551078.jpg" alt="KNAUER: AZURA® Bio Compact AC FPLC System." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_AZURA_Bio_Compact_AC_FPLC_System_6_a874551078.jpg 245w," sizes="100vw" width="1506" height="600">Design your AZURA Bio purification system to fit your needs. Multiple functionalities such as automatic sample injection via autosampler, column switching, buffer and sample selection, and fraction collection enable automation of the purification process.A wide range of detectors ensures the visibility of target molecules. Various flow rates and compatibility with columns from all vendors provide maximum flexibility. The intuitive PurityChrom® software integrates all the advantages of a versatile purification system.<h3>AZURA® Bio Lab Pilot FPLC System</h3><h4>High Flow Bio Purification FPLC System – up to 1000 ml/min</h4>Configure your FPLC system based on your purification requirements. The Pilot system is designed for scale-up and process applications. All system modules can be expanded with additional modules.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_AZURA_Bio_Lab_Pilot_FPLC_System_e208baf41d.jpg" alt="KNAUER: AZURA® Bio Lab Pilot FPLC System." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_AZURA_Bio_Lab_Pilot_FPLC_System_e208baf41d.jpg 156w," sizes="100vw" width="1000" height="1000"><h3>Key features</h3><ul data-start="93" data-end="1069"><li data-start="93" data-end="129">Flow rate: 0.001–1000 ml/min</li><li data-start="130" data-end="192">Injection system: Sample pump for large sample volumes</li><li data-start="193" data-end="351">Detection system:<ul data-start="221" data-end="351"><li data-start="221" data-end="276">Variable single wavelength UV detector (190–500 nm)</li><li data-start="279" data-end="351">Conductivity and pH-monitoring, pressure, and air sensors (optional)</li></ul></li><li data-start="352" data-end="465">Fraction collection: XY fraction collector for reliable collection of large volumes or numerous fractions</li><li data-start="466" data-end="559">Suitable for SEC, AC, IEX, and HIC, with upscaling capabilities</li><li data-start="560" data-end="651">Automation: High-flow buffer delivery and mixing for large-scale purification tasks</li><li data-start="652" data-end="739">System design: Same footprint as <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1625">AZURA Lab FPLC systems</a> for compact scalability</li><li data-start="740" data-end="871">Software:<ul data-start="760" data-end="871"><li data-start="760" data-end="831">Intuitive and powerful PurityChrom® software in basic configuration</li><li data-start="834" data-end="871">21 CFR Part 11 compliant software</li></ul></li><li data-start="872" data-end="1069">Scalability:<ul data-start="895" data-end="1069"><li data-start="895" data-end="965">Configure your FPLC system based on your purification requirements</li><li data-start="968" data-end="1069">Scale-up is possible with the same flexibility and software while maintaining a minimal footprint</li></ul></li></ul>

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