Ask any analytical chemist which hyphenated technique has become indispensable over the past decade, and the answer will almost certainly be the same: tandem chromatography–mass spectrometry. Whether it is <a target="_blank" rel="noopener noreferrer" href="https://www.organomation.com/preparing-samples-for-lc-ms/ms-analysis">LC–MS/MS</a> quantifying a novel biologic’s metabolic fate, or <a target="_blank" rel="noopener noreferrer" href="https://www.organomation.com/preparing-samples-for-gc-ms/ms-analysis">GC–MS/MS</a> chasing per- and polyfluoroalkyl substances (PFAS) down to sub-part-per-trillion levels in municipal water, the combination of chromatographic separation with the specificity of tandem mass detection has become the analytical workhorse of choice across virtually every regulated sector.Below we examine the key forces propelling this expansion, from biopharma pipeline dynamics and PFAS regulatory mandates to AI-driven automation and reshoring of pharmaceutical manufacturing—and explore what each trend means for laboratories managing sample preparation and analytical workflows.<h3>Biopharma: The Engine Room of LC–MS/MS Demand</h3><h4>GLP-1 Agonists and the Metabolomics Gold Rush</h4>The explosive commercial and scientific interest in GLP-1 receptor agonists—<a target="_blank" rel="noopener noreferrer" href="https://www.sepscience.com/advancing-glp-1-peptide-analysis-chromatography-challenges-and-innovations-12163">semaglutide and related peptide therapeutics </a>for diabetes and obesity—has dramatically expanded the analytical demands placed on tandem MS platforms. Discovery programs require precise quantification of peptide drug candidates and endogenous biomarkers across complex biological matrices. These workflows rely on high-sensitivity LC–MS/MS for pharmacokinetic profiling, receptor occupancy studies, and metabolomics characterization. Metabolomics is, in fact, projected to be the fastest-growing application segment in mass spectrometry, driven in part by its growing role in cancer screening, biomarker discovery, and metabolic disease research.I have been spending more time learning about GLP-1s because this is the hot topic that people want to discuss on the Concentrating on <a target="_blank" rel="noopener noreferrer" href="https://open.spotify.com/show/1wZg67rCjoGju4yhqxI3tL?si=n9GLz9zjSCOrVfXPxFPhng&amp;nd=1&amp;dlsi=52868e027aad4d22">Chromatography podcast</a>. With that said, I was astounded looking at CNBC.com during breakfast this morning to see that <a target="_blank" rel="noopener noreferrer" href="https://www.cnbc.com/2026/03/21/glp-1-diets-restaurants-protein-fiber-weight-loss-drugs.html">one in eight Americans are currently taking one of these drugs such as Ozempic</a>.<h4>Antibody–Drug Conjugates and Gene Therapy: Complexity at Every Step</h4>The ascent of antibody–drug conjugates (ADCs) and gene therapies has introduced a new level of analytical complexity. ADCs blend the target specificity of monoclonal antibodies with the cytotoxic potency of small-molecule payloads—and characterizing the linker chemistry, drug-to-antibody ratio (DAR), and conjugate stability demands high-resolution LC–MS/MS at every stage from discovery through QC release testing. Gene therapy vectors require equally rigorous characterization of impurities, aggregates, and empty/full capsid ratios.This translates into a direct need for low-evaporation, high-recovery concentration methods that preserve labile protein structures and maintain sample integrity prior to LC–MS/MS injection. <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/article/5392">Nitrogen evaporation workflows</a> that minimize oxidative stress and maintain sample temperature are increasingly critical in these pipelines.<h4>Precision Medicine and Multi-Omics Integration</h4>The shift toward precision medicine has accelerated adoption of high-throughput, multi-analyte MS platforms. Proteomics, metabolomics, and lipidomics workflows are converging on a single analytical platform—tandem MS—and generating datasets of a scale and complexity that were unimaginable ten years ago.Make no mistake: the triple quadrupole serves an irreplaceable role in quantitative targeted analysis. At the same time, <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products?category=134&amp;manufacturerItems=3">Orbitrap </a>and Q–TOF hybrid platforms are growing rapidly as researchers demand full-scan accurate mass for untargeted discovery.<h3>Environmental Mandates: PFAS Testing Drives Adoption</h3>Environmental testing is something that every person, chemist or not, can understand the importance of. Mounting mandates from the U.S. Environmental Protection Agency and European regulators regarding PFAS—the “forever chemicals” whose extraordinary environmental persistence is matched only by the analytical challenge of detecting them at trace levels—have created immediate, compliance-driven investment in LC–MS/MS infrastructure.<h4>The Regulatory Framework Chemists Need to Know</h4>The EPA has codified a suite of LC–MS/MS-based methods as the analytical standard for PFAS in water and solid matrices:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://blog.organomation.com/blog/epa-533-drying-down-pfas-samples-after-spe">EPA Method 533</a>: Weak anion exchange SPE combined with LC–MS/MS; covers 25 PFAS including short-chain compounds in drinking water.</li><li><a target="_blank" rel="noopener noreferrer" href="https://blog.organomation.com/blog/sample-concentration-epa-method-537-pfas-determination">EPA Method 537.1</a>: Reversed-phase SPE followed by LC–MS/MS; covers 18 PFAS including the GenX compound, with method detection limits in the low ng/L range.</li><li><a target="_blank" rel="noopener noreferrer" href="https://www.agilent.com/en/solutions/environmental/water-testing/pfas-in-water/us-epa-method-8327?srsltid=AfmBOooCY1pcavj7B1PH-75d3HO4BGDglNlhmyTyrpDY3zvUksMO1dlg">EPA Method 8327</a>: LC–MS/MS for selected PFAS in prepared extracts of aqueous and solid matrices.</li><li><a target="_blank" rel="noopener noreferrer" href="https://blog.organomation.com/blog/preparing-diverse-sample-matrices-for-epa-method-1633">EPA Draft Method 1633</a>: The emerging benchmark for PFAS in non-aqueous matrices—aqueous, solid, biosolids, and tissue—quantifying up to 40 PFAS.</li></ul>All of these methods designate LC–MS/MS, specifically LC coupled to triple quadrupole or tandem-in-time platforms operating in negative electrospray ionization mode with multiple reaction monitoring (MRM), as the required or recommended analytical technique. PFAS analysis is, at its core, an LC–MS/MS problem.<h4>The Sample Preparation Bottleneck</h4>Chemists who have worked with PFAS methods understand the particular demands they place on sample preparation. The ubiquity of<a target="_blank" rel="noopener noreferrer" href="https://blog.organomation.com/blog/tackling-pfas-contamination-practical-insights-from-epa-537.1-method-development"> PFAS in laboratory materials</a>—PTFE tubing, some SPE sorbents, standard bench supplies—means that blank contamination control is as analytically demanding as the detection itself. EPA 537.1 requires that sample volumes of approximately 250 mL be extracted and reconstituted in as little as 1 mL, creating a 250:1 concentration factor that can expose even trace contamination in the sample processing chain. The installation of a delay column between the LC pump and autosampler to prevent instrument background interference is now standard practice.This is precisely where robust, <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/article/5385">inert nitrogen evaporation </a>systems earn their keep. PFAS workflows that use nitrogen-assisted evaporation to concentrate extracts prior to reconstitution benefit from materials that avoid PTFE and other fluoropolymers that can leach PFAS background—a consideration Organomation addresses in its concentration system designs.The analytical community is also moving beyond targeted PFAS analysis. High-resolution accurate mass (HRAM) spectrometry via Orbitrap technology, paired with non-targeted screening workflows, is gaining traction for the identification of the more than 5,000 currently catalogued PFAS compounds and the novel structures that continue to emerge. LC–MS/MS remains the quantitative gold standard; HRAM provides the discovery layer.<h3>Technological Trends Reshaping the LC–MS/MS Workflow</h3><h4>Artificial Intelligence and Automated Data Interpretation</h4>The datasets generated by modern tandem MS platforms—particularly in omics applications—are too large and too complex for conventional manual review. AI-driven spectral deconvolution, automated peak integration, and AI-assisted hypothesis generation are now embedded in the software suites accompanying leading instruments. <a target="_blank" rel="noopener noreferrer" href="https://www.agilent.com/about/newsroom/presrel/2022/17feb-gp22004.html?srsltid=AfmBOop3warRIaEojXM2YyMML6RXfMIDzE-Wm0h-SiKkkocBeeET2m7u">Agilent’s acquisition of Virtual Control’s ACIES </a>software specifically to automate LC–MS and GC–MS data analysis is emblematic of this direction.For laboratory managers, AI integration means smaller specialized teams can operate high-throughput multi-analyte workflows—but it also means that the front-end sample preparation must be even more reproducible, since algorithmic interpretation amplifies inconsistencies introduced upstream.<h4>Online SPE Coupling and “Chromatography Without Walls”</h4>A significant trend is the integration of solid-phase extraction directly into the HPLC flow path—so-called online SPE–HPLC coupling. Systems that combine extraction and chromatographic separation in a single analytical instrument reduce manual transfer steps, minimize the risk of sample loss or contamination, and dramatically increase throughput. For analytes at very low concentrations, online SPE provides the on-column concentration capability that traditional offline preparation achieves with manual evaporation steps.That said, offline sample preparation—including <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/article/5392">nitrogen-assisted evaporation</a> under controlled conditions, <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/2407">liquid–liquid extraction</a>, and protein precipitation—retains significant advantages in flexibility, matrix handling, and the ability to process sample volumes that exceed online system capacity. The two approaches are increasingly complementary rather than competitive in well-designed analytical laboratories.<h4>High-Purity Solvents and Reference Materials</h4>As detection limits push further into the femtogram range and regulatory methods demand demonstrable blank performance, the quality of analytical consumables—mobile phase solvents, derivatization reagents, reference standards—has moved from background consideration to front-of-mind. Method validation in regulated environments now routinely requires vendor certification of solvent purity at a level that directly interfaces with instrument performance.<h3>The Ever-Present Need for Sample Evaporation</h3>As LC–MS/MS methods push detection limits lower, the analytical burden shifts increasingly upstream. The quality of the concentration, cleanup, and reconstitution steps preceding injection determines whether the instrument’s theoretical sensitivity is achievable in practice.Several specific developments are particularly relevant:<ul><li>ADC and gene therapy characterization workflows require gentle, low-temperature evaporation that preserves protein structure and prevents aggregation prior to LC–MS/MS. Nitrogen evaporation under controlled conditions is the preferred approach.</li><li>PFAS trace analysis demands evaporation systems constructed from PFAS-inert materials, with rigorous attention to avoiding fluoropolymer surfaces throughout the sample path.</li><li>High-throughput pharmaceutical QC driven by reshoring demands parallel processing capability—multi-position evaporators that maintain consistent flow and temperature across all positions simultaneously.</li><li>Multi-omics and metabolomics workflows generate large sample batches that benefit from automated, walk-away evaporation with programmable endpoints to ensure reproducible final volumes across a cohort.</li></ul>Tandem chromatography–mass spectrometry is not merely growing; it is becoming structurally embedded in the analytical workflows of every major regulated industry. The convergence of biopharma complexity, PFAS regulatory mandates, AI-enabled data analysis, and pharmaceutical reshoring is creating a multi-year demand cycle that will require laboratories to invest not only in instruments, but in the entire sample preparation ecosystem that makes those instruments perform.For analytical chemists, the practical takeaway is this: as mass spectrometry sensitivity continues to advance, the sample preparation step becomes the binding constraint on method performance. Whether you are developing a new PFAS method to meet EPA 1633, characterizing an ADC’s drug-to-antibody ratio, or running a 500-sample metabolomics cohort overnight, the reliability and cleanliness of your concentration and cleanup workflow determines the quality of every data point that follows.&nbsp;

The Continued Rise of Tandem Chromatography–Mass Spectrometry

<h3>A Practical Guide to Getting the Most from Syringe Filters: Tips, Tricks, and Common Pitfalls</h3>Syringe filters play a crucial role in chromatography and many other laboratory applications by removing particulate matter before analysis. Proper sample filtration helps protect analytical instruments, extends column lifetime, and improves data quality. However, selecting an unsuitable filter—or using one incorrectly—can introduce contamination, reduce filtration efficiency, or even compromise analytical results. The following recommendations will help you avoid common mistakes and ensure reliable filtration every time.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_Avoiding_Common_Syringe_Filter_Mistakes_3_150e8c1c2b.webp" alt="KNAUER: Avoiding Common Syringe Filter Mistakes" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_Avoiding_Common_Syringe_Filter_Mistakes_3_150e8c1c2b.webp 133w," sizes="100vw" width="1276" height="1496"><h4>1. Improper Filter Handling</h4>Using excessive force during filtration or attempting to reuse disposable syringe filters can damage the membrane and increase the risk of sample contamination.<ul><li>Solution: Apply slow, even pressure throughout the filtration process and always dispose of single-use filters after one use. If the flow rate decreases noticeably, replace the filter instead of applying additional force.</li></ul><h4>2. Selecting an Inappropriate Pore Size</h4>Using the wrong pore size may either fail to remove unwanted particles or cause the membrane to clog prematurely, reducing filtration efficiency.<ul><li>Solution: A 0.45 µm membrane is generally suitable for routine particulate removal, while a 0.22 µm membrane is recommended for finer filtration and bacterial removal. Samples with higher viscosity may require a pre-filter to prevent rapid clogging. It is also important to consider the intended analytical technique. For example, 0.22 µm filters are typically preferred for UHPLC and LC-MS applications, whereas 0.45 µm filters are often sufficient for conventional HPLC analyses.</li></ul><h4>3. Choosing the Wrong Membrane Material</h4>Different membrane materials exhibit different chemical resistance. Using an incompatible membrane may lead to degradation of the filter, sample contamination, or complete filtration failure.<ul><li>Solution: Always verify solvent compatibility before filtration. PTFE membranes are an excellent choice for organic solvents, while PES and nylon membranes are better suited to aqueous samples. If compatibility is uncertain, perform a small-scale trial before filtering valuable samples.</li><li>Pro Tip: For additional guidance, see our blog article "How to Choose the Right Membrane for your Syringe Filter", which provides a detailed comparison of membrane materials and their recommended applications.</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_Avoiding_Common_Syringe_Filter_Mistakes_2_e47021fb11.jpg" alt="KNAUER Sepapure® Syringe Filters are available with multiple membrane materials, each identified by a dedicated color code for quick and reliable selection." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_Avoiding_Common_Syringe_Filter_Mistakes_2_e47021fb11.jpg 245w," sizes="100vw" width="1580" height="902"><h4>4. Ignoring Filter Capacity</h4>Using a filter with insufficient capacity can result in rapid membrane blockage, increasing filtration time and reducing laboratory productivity.<ul><li>Solution: When filtering larger sample volumes, choose high-capacity syringe filters or introduce a pre-filtration step. Never force liquid through a clogged membrane, as doing so may damage the filter and negatively affect sample quality.</li></ul><h4>5. Overlooking Sample Adsorption</h4>Certain membrane materials may adsorb analytes of interest, leading to lower recoveries and potentially affecting quantitative results.<ul><li>Solution: For protein samples or other adsorption-sensitive analytes, select membranes with low binding characteristics, such as nylon or glass fiber, whenever appropriate. Performing a small recovery test before routine analysis can help identify potential analyte losses.</li></ul><h4>6. Failing to Optimize Filtration Performance</h4>Slow filtration is more than just an inconvenience—it often indicates that the filtration conditions are not optimal.<ul><li>Solution: If filtration becomes unusually slow, investigate possible causes such as membrane clogging, excessive sample viscosity, or an unnecessarily small pore size. Depending on the sample, dilution or sequential filtration using progressively finer filters may significantly improve performance.</li></ul><h4>Final Thoughts</h4>Selecting the appropriate syringe filter is a straightforward process, but overlooking small details can have a significant impact on analytical performance. Choosing the correct membrane material, pore size, and filtration strategy helps improve laboratory efficiency, protects chromatography systems and columns, and contributes to accurate, reproducible analytical results.With the right syringe filter and proper filtration technique, you can minimize sample preparation problems and maximize confidence in every analysis.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_Avoiding_Common_Syringe_Filter_Mistakes_4_983a15e289.jpg" alt="KNAUER: Sepapure® Syringe Filter Selection" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_Avoiding_Common_Syringe_Filter_Mistakes_4_983a15e289.jpg 245w," sizes="100vw" width="1160" height="627">Happy filtering!

Avoiding Common Syringe Filter Mistakes

News from LabRulezLCMS Library - Week 27, 2026

Article

Product

Application

Academy

Poster

Everything from the world of analytical chemistry in one place. We connect people in solving their problems. At Labrulez you will find all the necessary information easily, quickly and clearly. Stop searching and start finding.

LabRulez

Organomation, founded in 1959, designs and manufactures high-quality nitrogen evaporators and extraction systems. Known for innovation and durability, their lab instruments are used globally for efficient sample preparation with strong customer support.

Organomation

Based in Berlin, KNAUER is a medium-sized, owner-managed company that has been serving the sciences since 1962. We develop and manufacture scientific instruments of superior quality for liquid chromatography, including: Analytical HPLC/UHPLC, Preparative HPLC, Fast protein liquid chromatography (FPLC), Multi-column chromatography/Simulated moving bed (SMB) chromatography. High pressure dosing, in-line detection systems, and osmometry are additional business areas.

KNAUER

DataApex

Separation Science

Agilent Technologies

Thermo Fisher Scientific

Waters Corporation

The calculation of signal to noise ratio is a critical parameter during method development, method validation and routine monitoring the performance of a chromatographic method. Both Limit of Detection (LOD or LDL) and Limit of Quantitation (LOQ or LQL) are based on signal to noise ratio. Empower can calculate signal to noise ratio in many ways. While we designed this functionality in Empower to comply with pharmacopeia requirements, there are alternative methods for this calculation.
Key points of discussion will be:
<ul>
<li>Calculating Signal to Noise ratio as per USP/EP/JP Requirements</li>
<li>Calculating Signal to Noise ratio using other options within the System Suitability option</li>
<li>Calculating Signal to Noise ratio without the System Suitability Option</li>
</ul>
Please join us for a live discussion. As always, don’t forget to bring your Empower questions for this exclusive opportunity to ask our experts anything about Empower Software.
<blockquote>
Presenter: Neil Lander (Principal Product Manager, Waters Corporation)
</blockquote>
<blockquote>
Neil has worked for Waters Corporation since 1994 and has held a variety of positions including Technical Support Specialist, Technical Trainer, Manager Customer Education and currently, Principal Marketing Manager focusing on Informatics solutions. He provides internal support for Empower Chromatography Data System and is focused on developing laboratory software solutions that help organizations achieve their scientific and operational objectives. Prior to joining Waters, he was an analytical chemist where he gained experience in both the cosmetics and specialty chemical industries.
</blockquote>

Waters Corporation: Empower Tips: Ask Me Anything About Calculating Signal to Noise Ratio

Empower Tips: Ask Me Anything About Calculating Signal to Noise Ratio

The calculation of signal to noise ratio is a critical parameter during method development, validation and monitoring the performance.

Empower Tips: Calculating Signal to Noise Ratio

<h5>Solving Problems that Matter: Risk Mitigation in the Pharma QC Laboratory</h5>
Expert Insights 3-Part Webinar Series: Risk Assessment, Control Strategies, and Intuitive Innovation to Improve Data Quality, Data Integrity and Lab Productivity. 
Pharma QC labs are facing increasing pressure on the cost of quality while maintaining compliance and assuring patient safety. From the harmonization of USP &lt;621&gt; to Empower™ workflows supporting data integrity to improving method transfer outcomes, you will learn from subject matter experts how to reduce errors and mitigate risk for reproducible data and enhanced productivity. 
Who should attend
<ul>
<li>Pharma QC Lab directors, managers and senior scientists with a drive to reduce errors, improve lab productivity and enhance data quality &amp; integrity.</li>
</ul>
<h3>PART 3 l Creating Efficiency in Your Routine Workflow with Simple Automation Steps in Empower</h3>
<ul>
<li>Wednesday, August 30th, 11:30-12:30 ET</li>
</ul>
According to the PIC/S guidance, complex or open-ended processes that lead to subjective interpretation can result in an increase in data failures. One way to reduce this risk is with a simplified, well-defined process. Empower software enables you with tools to create structure in your chromatographic processes and workflow.
In this presentation we will define a chromatographic workflow with Empower software to support data integrity goals - starting with method development, method validation, and routine usage to data acquisition, data processing, reporting results, and using control charts to track and trend data. This presentation will also introduce new features coming to Empower 3.8.0 such as safeguards to prevent common errors, enhanced column tracking &amp; history and more detailed audit trails.
<blockquote>
Presenter: Neil Lander (Principal Product Manager - Informatics Group, Waters Corporation)
</blockquote>
<blockquote>
Neil has worked for Waters Corporation since 1994 and has held a variety of positions including Technical Support Specialist, Technical Trainer, Manager Customer Education and currently, Principal Marketing Manager in Waters in the Informatics group. Neil provides internal support for Empower CDS software and is focused on developing laboratory software solutions that help organizations achieve their scientific and operational objectives. Prior to joining Waters Corporation, he was an analytical chemist where he gained experience in both the cosmetics and specialty chemical industries.
</blockquote>

Waters Corporation: Creating Efficiency in Your Routine Workflow with Simple Automation Steps in Empower

Creating Efficiency in Your Routine Workflow with Simple Automation Steps in Empower

Chromatographic workflow with Empower software to support data integrity goals.

Creating Efficiency in Your Routine Workflow

The USP general chapter &lt;1220&gt; &quot;Analytical Procedure Life Cycle&quot; became official in May 2022. The adoption of this guideline makes your lab ready for the adoption of the ICH Q14 “Analytical Procedure Development” and Q2(R2) “Analytical Validation”, expected later in 2023.
These quality guidelines are relevant for both analytical development and QC testing at pharma companies. Empower and Waters solutions support all 3 steps of the guideline, namely: 
<ul>
<li>Development
</li>
<li>Validation
</li>
<li>On-going Verification
</li>
</ul>
In Part I we will describe how Empower supports Step 1 – Development through the integration with selected QbD software that enables the required DoE approach.
<blockquote>
Presnter: Andrea Gheduzzi (Principal Pharma Development Specialist)
</blockquote>

Waters Corporation: USP <1220> and ICH Q14/Q2(R2) using Empower / Part I - Development

USP <1220> and ICH Q14/Q2(R2) using Empower / Part I - Development

Development through the integration with selected QbD software that enables the required DoE approach.

USP <1220> and ICH Q14/Q2(R2) using Empower - Development

In this work, we present novel, automated, and integrated software to support these workflows using LC HRAM MS instruments.
Purity and sequencing data are presented for a multitude of oligos including antisense, aptamer, and long synthetic samples.
<blockquote>
Presenter: Shashank Jain, PhD (Mass Spec product specialist, New England, Agilent Technologies, Inc.)
</blockquote>

Agilent Technologies: Relieve the Pressure of Oligo Characterization by Implementing Automated Workflows

Relieve the Pressure of Oligo Characterization by Implementing Automated Workflows

Novel, automated, and integrated software to support these workflows using LC HRAM MS instruments.

Oligo Characterization by Implementing Automated Workflows

Are you using Chromeleon CDS but don’t feel like an expert just yet? Are you interested in a CDS that is intuitive and user-friendly? Whether you’re a day-to-day user or just curious about a new CDS, this is the webinar for you!
What this session covers:
<ul>
<li>Fundamentals of Chromeleon CDS</li>
<li>How to create custom reports</li>
<li>New features in Chromeleon 7.3.2 CDS</li>
<li>Benefits of upgrading from workstation to enterprise with the Ardia Platform</li>
</ul>
<blockquote>
Presenter: Seth Sheridan (Product Specialist III, Enterprise CDS, Americas, Thermo Fisher Scientific)
</blockquote>
<blockquote>
Seth is an Enterprise CDS technical specialist who has supported Thermo Fisher’s Chromeleon software for over 3 years. Prior to this, he used Chromeleon and other CDS systems in labs at DuPont, DOW, and Eurofins. He holds a B.S. in Chemistry and Biochemistry and enjoys working closely with chromatographers to solve their software issues and improve their processes.
</blockquote>

Thermo Scientific: Learn the secrets of Chromeleon CDS: Expert advice and tips

Learn the secrets of Chromeleon CDS: Expert advice and tips

Fundamentals of Chromeleon CDS. How to create custom reports. New features in Chromeleon 7.3.2 CDS. Benefits of upgrading from workstation to enterprise.

Chromeleon CDS is built for IT and compliance without compromising on user friendliness. Join this webinar to learn how easy it is to ensure data integrity, compliance, and future-proof your lab using Chromeleon CDS.
What this session covers:
<ul>
<li>Learn how Chromeleon CDS can simplify audit trail reviews</li>
<li>How to implement administrator-controlled user access to ensure data integrity and compliance with GxP and 21 CFR Part 11</li>
<li>Learn how Chromeleon CDS supports business continuity through network failure protection with 24/7 uptime</li>
<li>Understand the seamless scalability from workstation to enterprise</li>
</ul>
<blockquote>
Presenter: Seth Sheridan (Product Specialist III, Enterprise CDS, Americas, Thermo Fisher Scientific)
</blockquote>
<blockquote>
Seth is an Enterprise CDS technical specialist who has supported Thermo Fisher’s Chromeleon software for over 3 years. Prior to this, he used Chromeleon and other CDS systems in labs at DuPont, DOW, and Eurofins. He holds a B.S. in Chemistry and Biochemistry and enjoys working closely with chromatographers to solve their software issues and improve their processes.
</blockquote>

Thermo Scientific: Data integrity, compliance and IT efficiency made easy

Data integrity, compliance and IT efficiency made easy

Learn how Chromeleon CDS can simplify audit trail reviews. Understand the seamless scalability from workstation to enterprise...

Dear Orbitrap users,
We are pleased to invite you to our Autumn 2023 version of virtual activities to support our Proteome Discoverer (PD) software users.
The workshops are designed to bring beginners up-to-speed with best practices as well as allow advanced users to interact with software experts and enquire how to get the most out of their data. Additionally, a dedicated session specialized in Tandem Mass Tagging (TMT) data processing will follow.
The content is delivered through online workshops, 2-3 hours each, via MS-Teams. The workshops feature live exercises on pre-distributed data, discussion of PD features, parameters, and optimized settings. The sessions are hands-on and highly interactive, so get the best experience by having PD 2.4, 2.5, 3.0 with CHIMERYS™, or 3.1 with CHIMERYS up and running. <a href="https://www.thermofisher.com/cz/en/home/industrial/mass-spectrometry/liquid-chromatography-mass-spectrometry-lc-ms/lc-ms-software/multi-omics-data-analysis/proteome-discoverer-software.html">Click HERE</a> to download a free 60-day trial version of the latest Proteome Discoverer software release and CHIMERYS algorithm.
The sessions allow ample time for the participants to get their PD-related questions answered in real time. We will also review the new features in PD 3.1. The workshops will be taught in English, but participants can use MS Team`s instant subtitles in their preferred language.
<h5>General Proteome Discoverer software training:</h5>
<ul>
<li>Tuesday 5th September: 13.30-17.00 CEST (Berlin time)</li>
<li>Wednesday 6th September: 13.30-17.00 CEST (Berlin time)</li>
<li>Thursday 7th September: 13.30-17.00 CEST (Berlin time)</li>
</ul>

Thermo Scientific: Proteome Discoverer software workshops (General Proteome Discoverer software training)

Proteome Discoverer software workshops (General Proteome Discoverer software training)

The workshops are designed to bring beginners up-to-speed with best practices as well as allow advanced users to interact with software experts.

General Proteome Discoverer software training

Every organization has unique needs regarding their laboratory processes, workflows, and overall mission.
When considering ways to meet those needs, it is vital that an organization evaluates the potential resources they can implement, from laboratory instrumentation to software solutions. The goal is to add value and increase optimization. 
Selecting a software solution is a decision that will have a direct, intense impact on your lab. It will affect how efficiently your staff works, how streamlined your processes are, and how accurately your work can be accomplished. You want to make sure that the impact is positive. A laboratory information management system (LIMS) is a necessary resource because it can store and aggregate your data in one place, streamline your workflows and processes, and increase efficiency, reliability, and value – all which are limited when managed manually. It’s important to choose a solution that is easy-to-use, with minimal customization that addresses the key challenges of your industry and can integrate with existing instrumentation and software systems. Understand the key considerations when selecting a LIMS to best meet your goals and elevate your lab.
By attending this presentation you will learn about:
<ul>
<li>The value of choosing a LIMS solution that meets your laboratory’s requirements and needs
</li>
<li>The impact of making the right choice to elevate your lab’s productivity, efficiency, and ability to deliver high quality results
</li>
</ul>
<blockquote>
Presenter: Adam Collins (Senior Product Specialist, Digital Science Solutions, Thermo Fisher Scientific)
</blockquote>
<blockquote>
As Senior Product Specialist for Digital Science Solutions at Thermo Fisher Scientific, Adam specializes in providing software demonstrations and technical support for organizations across multiple industry sectors who are assessing Thermo Fisher Scientific’s LIMS solutions for their laboratory needs. He has over five years of experience as a technical product specialist for laboratory software. Adam has Doctor of Philosophy and Bachelor of Science degrees in Microbial Genetics and Microbiology from the University of Nottingham.
</blockquote>

Separation Science: How to choose the right LIMS solution

How to choose the right LIMS solution

Understand the key considerations when selecting a LIMS to best meet your goals and elevate your lab.

Free webinar focusing on new Clarity 9.0 features, including the improved workflow for batches, the new integration algorithm, and much more. We will add some Tips on how to use Clarity software effectively and provide space for your questions.

Clarity 9.0 Webinar 

Free webinar focusing on new Clarity 9.0 features, including the improved workflow for batches, the new integration algorithm, and much more.

In Part II we describe how Empower supports both Step 2 – Validation by translating your written SOP into an Empower Method Validation Manager (MVM) scheme and Step 3 – On-going verification through the setup of Trend reports in Empower

Waters Corporation: USP 1220 & ICH Q14-Q2(R2) Part II – Validation & Verification

USP 1220 & ICH Q14-Q2(R2) Part II – Validation & Verification

Validation by translating your written SOP into an Empower Method Validation Manager (MVM) scheme.

LCMS webinars focusing on Software - page 32