Given the ever-increasing demands on drinking water quality and societal pressure for the reuse of treated wastewater, somatic coliphages are being monitored as novel indicators for evaluating the efficiency of water treatment and purification processes. Therefore, it is highly important to monitor their presence in specific types of water, particularly water intended for human consumption.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ALS_Czech_Republic_Enviro_Mail_18_Europe_Tracking_the_Unseen_The_Identification_of_Somatic_Coliphages_in_All_Water_Types_5e15f40bb7.jpg" alt="ALS Czech Republic:&nbsp;EnviroMail™ 18/Europe: Tracking the Unseen: The Identification of Somatic Coliphages in All Water Types: Figure 1: Example of plaque units on the Petri dish." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ALS_Czech_Republic_Enviro_Mail_18_Europe_Tracking_the_Unseen_The_Identification_of_Somatic_Coliphages_in_All_Water_Types_5e15f40bb7.jpg 245w," sizes="100vw" width="1640" height="678"><h3>Introduction</h3>Somatic coliphages are currently a significant topic in the realm of water quality control, as they exhibit certain morphological similarities to human enteric viruses and may serve as potential indicator organisms for viral contamination in water. Somatic coliphages are viruses that infect bacteria such as Escherichia coli and are, therefore, ideal indicators of faecal contamination in water. Although somatic coliphages are not pathogenic to humans, they thrive in the same conditions and exhibit very similar behaviour to viruses that are hazardous to humans. These pathogenic, so-called enteric viruses can cause highly unpleasant infectious diseases of the digestive tract in humans. Consequently, if somatic coliphages are detected in the analysed water, there is a high probability that pathogenic viruses are also present in the water.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ALS_Czech_Republic_Enviro_Mail_18_Europe_Tracking_the_Unseen_The_Identification_of_Somatic_Coliphages_in_All_Water_Types_2_647eb292e5.jpg" alt="ALS Czech Republic:&nbsp;EnviroMail™ 18/Europe: Tracking the Unseen: The Identification of Somatic Coliphages in All Water Types: Figure 2: The Phi X 174 bacteriophage illustrative picture." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ALS_Czech_Republic_Enviro_Mail_18_Europe_Tracking_the_Unseen_The_Identification_of_Somatic_Coliphages_in_All_Water_Types_2_647eb292e5.jpg 245w," sizes="100vw" width="679" height="207"><h3>Why is Coliphages Testing Essential?</h3>Coliphages play a crucial role as an indicator of water quality. Their presence can signal potential risks to public health, such as the presence of enteric viruses and bacteria.Monitoring somatic coliphages serves as an effective early warning system against faecal contamination in water supplies. When higher levels of these viruses are detected, it prompts further investigations and interventions, thereby aiding in the prevention of waterborne diseases. Moreover, tracking somatic coliphage levels is essential for assessing the effectiveness of water treatment processes, including disinfection and filtration, thus safeguarding water quality.Ensuring compliance with regulatory requirements and standards for the sanitary quality of drinking and hot water is another critical aspect protecting the public health. The study of somatic coliphages and their behaviour in the environment contributes to epidemiological screening efforts. Such a research provides valuable insight into the surveillance of waterborne diseases and can inform about diseases prevention strategies. Understanding the patterns and behaviour of coliphages in different environmental conditions enhances our ability to predict and mitigate potential outbreaks.<h3>Legislation</h3>The Directive of the European Parliament and of the Council (EU) 2020/2184 from 16 December 2020 on the quality of water intended for human consumption came into force on 12 January 2021, which is a comple- tely recast amendment to the Directive 98/83/EC. The implementation of this Directive into national legislation was planned for the end of 2022 / 2023. Somatic coliphages are also mentioned in the Regula- tion 2020/741 of the European Parliament and of the Council (EU) of 25 May 2020 on minimum requirements for water reuse, which should provide Member States with relatively simple rules for the reuse of treated urban water.<h3>The Methodology for Somatic Coliphages Determination</h3>Since somatic coliphages are viruses, water analysis is carried out in a completely different way compared to determination of bacterial parameters. The analysis is very complex and consists of several subsequent steps, where it is necessary to adhere to the exact time frame and specific conditions.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ALS_Czech_Republic_Enviro_Mail_18_Europe_Tracking_the_Unseen_The_Identification_of_Somatic_Coliphages_in_All_Water_Types_5_3797409a4d.jpg" alt="ALS Czech Republic:&nbsp;EnviroMail™ 18/Europe: Tracking the Unseen: The Identification of Somatic Coliphages in All Water Types: Table 1: Methods overview." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ALS_Czech_Republic_Enviro_Mail_18_Europe_Tracking_the_Unseen_The_Identification_of_Somatic_Coliphages_in_All_Water_Types_5_3797409a4d.jpg 245w," sizes="100vw" width="829" height="334"><h3>Best Sampling and Transportation Practise</h3>For the proper execution of the analysis and to deliver high-quality and reliable results to clients, it is essential to ensure:<div><div><div><div><ul><li>Validated matrices: drinking, raw, bottled, surface, ground, processing and waste water.&nbsp;</li><li>Use the correct sample container: for coliphages analysis the 500mL white plastic container filled with sodium thiosulphate (this solution neutralises chlorine from water pipes, preventing the death of live microorganisms and phages that are sensitive to the presence of chlorine, and thereby avoiding the reporting of false negative results).&nbsp;</li><li>Minimum amount of sample: 200 mL of tested water.&nbsp;</li><li>Compliance with appropriate conditions during sample transport to the lab must be ensured: cooling the sample in the range 4 - 8°C.&nbsp;</li><li>The analysis must be performed within three days (Holding Time 72 hours) of sampling. For this reason, samples must be delivered to the laboratory no later than Thursday morning in the given week.</li></ul><h3>Evaluation of Cultivation: Determination of Plaque Units (unit PFU - Plaque Forming Unit)</h3><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ALS_Czech_Republic_Enviro_Mail_18_Europe_Tracking_the_Unseen_The_Identification_of_Somatic_Coliphages_in_All_Water_Types_4_134e59c5e5.jpg" alt="ALS Czech Republic:&nbsp;EnviroMail™ 18/Europe: Tracking the Unseen: The Identification of Somatic Coliphages in All Water Types: Figure 3: (A) An optimal number of plaque units for counting and evaluation; (B) Borderline number of plaque units which can be counted and evaluated. Further dilution of sample is needed, and membrane filtration method is not suitable; (C) Sample is too contaminated for plaque units to be enumerated and evaluated. Overgrown plates are discarded and sample dillution must be performed prior the next analysis. Membrane filtration method is not suitable." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ALS_Czech_Republic_Enviro_Mail_18_Europe_Tracking_the_Unseen_The_Identification_of_Somatic_Coliphages_in_All_Water_Types_4_134e59c5e5.jpg 245w," sizes="100vw" width="938" height="309"></div></div></div></div>

EnviroMail™ 18/Europe: Tracking the Unseen: The Identification of Somatic Coliphages in All Water Types

<h4>Is a Nitrogen Evaporator Faster than your Current Sample Concentration Method?</h4>In laboratory environments where sample preparation is a daily task, every minute counts. Whether you’re working in environmental testing, pharmaceuticals, food safety, or chemical analysis, sample evaporation is a necessary but often time-consuming step in your workflow.If your current evaporation method is slowing down your productivity—whether it’s <a target="_blank" rel="noopener noreferrer" href="https://blog.organomation.com/blog/manual-to-automated-solvent-drying-is-it-worth-the-switch?hsLang=en">evaporating samples by hand</a>, air drying in a fume hood, <a target="_blank" rel="noopener noreferrer" href="https://blog.organomation.com/blog/diy-evaporation-setups-vs.-professional-nitrogen-blowdown-systems-knowing-when-to-upgrade?hsLang=en">using a DIY setup</a>, or relying on an inefficient evaporator—you might be spending far more time than necessary on solvent removal.That’s where nitrogen evaporators come in. These systems use a steady stream of nitrogen gas and a gentle heat source to <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/article/5392">accelerate solvent evaporation</a>, offering a faster, more controlled, and more efficient solution than alternative methods. But just how much time could you save?<h3>Try Our Time-Saving Calculator</h3>To help you understand the potential efficiency gains, we’ve created a Nitrogen Evaporation Time-Saving Calculator. By inputting details about your current evaporation process, such as solvent volume, sample throughput, and evaporation time, you can get a customized estimate of how much time you could be saving every day.<h3>Why Traditional Evaporation Methods Are Holding You Back</h3>Many labs still rely on slow, manual, or outdated evaporation techniques that waste technician hours and introduce inconsistencies in sample preparation. Here are some of the most common methods—and their drawbacks:<h4 style="font-size:20px;">1. Evaporating Samples One by One by Hand</h4>Manually monitoring each sample while waiting for solvent evaporation is tedious and inefficient. This method requires constant supervision, limiting the amount of work a technician can complete in a day. If your lab is handling multiple samples daily, the lost time quickly adds up.<h4 style="font-size:20px;">2. Air Drying in a Fume Hood</h4>While this is a simple and low-cost method, it is also one of the least efficient. Air drying can take hours or even days, depending on the solvent, solvent volume, and environmental conditions. Since it relies on passive airflow without the addition of a heat source, evaporation times can be inconsistent, and there is always a risk of contamination or sample loss due to open exposure.<h4 style="font-size:20px;">3. DIY Evaporation Setups</h4>Some labs attempt to create their own evaporation solutions using hot plates, Schlenk lines, fans, or other makeshift nitrogen setups. While these may work temporarily, they often lead to uneven evaporation, loss of volatile compounds, inconsistent results across samples, and gas leaks that waste nitrogen or compressed air.<h4 style="font-size:20px;">4. Using an Evaporator That Isn’t Optimized for Your Needs</h4>Even if your lab is using a sample evaporator, it may not be designed for your solvent type, batch size, or throughput requirements. Some evaporators work best for certain solvents but struggle with others, while others are limited by the number of samples they can process at one time. If your current evaporator isn’t properly suited for your workflow, you could still be wasting hours on unnecessary evaporation time.<h3>The Benefits of Nitrogen Evaporators</h3>Switching to a <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products?category=3&amp;manufacturerItems=540">nitrogen evaporator</a> can drastically improve lab efficiency by reducing solvent evaporation times and increasing sample throughput. Here’s how:<ul><li>Significantly Faster Evaporation – A steady stream of nitrogen paired with a gentle heat source speeds up solvent removal compared to air drying or manual evaporation, while keeping your samples safe.</li><li>Higher Sample Throughput – Process multiple samples at once, rather than evaporating them one at a time.</li><li>More Consistent Results – Avoid inconsistencies caused by passive or DIY evaporation methods. Nitrogen evaporators provide controlled, reproducible conditions for each sample.</li><li>Reduced Technician Workload – Free up lab personnel for more important tasks instead of spending hours monitoring evaporation.</li><li>Better Solvent Control – Minimize the risk of over-drying or losing volatile compounds, which can happen with passive drying or DIY methods.</li></ul><h3>Maximize Your Lab’s Efficiency Today</h3>Your lab’s time is valuable—why spend it on slow, inefficient evaporation methods? Instead of wasting technician hours on manual monitoring or unreliable setups, invest in a nitrogen evaporator that accelerates evaporation and improves consistency.To make sure the switch to a nitrogen evaporator makes sense for your lab, be sure to use our Time-Savings Calculator. Simply enter your current evaporation details and find out how that compares to the evaporation time you could expect from a nitrogen concentrator.Stop letting inefficient evaporation slow down your workflow—make the switch to nitrogen evaporation and optimize your lab’s productivity today!

How much time can I save drying my samples in a nitrogen evaporator?

Institute of Microbiology of the CAS enters Biotech Company AffiPro to boost its applied research and to introduce new tools for development of biologicals and biosimilars.The transfer of cutting-edge scientific results into practice, faster development of new products for earlier diagnostics, and research in biological drugs will be enabled by the new joint venture created between Institute of Microbiology of the Czech Academy of Sciences (IMIC CAS) and the biotechnology company AffiPro s.r.o (LLC). Both partners own unique proprietary technologies and products for life science mass spectrometry. This strategic move opens up new opportunities for collaboration, especially in the field of personalized medicine.By entering the joint venture,&nbsp;biotech start-up company AffiPro (Company Registration Number 03889173) is becoming a&nbsp;spin-off of the Institute of Microbiology, which now owns 13.75% of the new entity, while 86.25% remains in possession of the current owners of AffiPro. The change has already been registered in the Commercial Register by the Municipal Court in Prague on May 14, 2025. &nbsp;&nbsp;&nbsp;“Our goal is to significantly accelerate and streamline the development of biological drugs while also delivering innovations that simplify the work of scientific teams in structural biology, life science mass spectrometry and clinical diagnostics,” says Petr Pompach, managing director and co-founder of AffiPro.“We use technologies such as immobilized enzyme reactors (IMERs), protein chips, &nbsp;and robotic systems for automated sample processing. These tools enable detailed analysis of post-translational modifications of proteins or structural characterization of proteins and nucleic acids,” he adds.According to Petr Novák, another AffiPro co-founder and head of the Laboratory of Structural Biology and Cell Signaling at the Institute of Microbiology CAS in the BIOCEV center, the company’s main objective is to contribute to the development of personalized medicine: “Our technologies are already being used for the analysis of proteins and biological drugs, as well as in clinical diagnostics. We are also developing tools for the detailed analysis of oligonucleotides, which will be useful in gene therapies and mRNA-based vaccines.”<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/MBU_Mikrobiologicky_ustav_AV_CR_vstupuje_do_biotechnologicke_spolecnosti_Affi_Pro_pomuze_to_vyvoji_novych_leciv_2_6aefdabcd5.jpg" alt="MBU: Institute of Microbiology Enters Biotech Company AffiPro: From left: RNDr. Petr Novák, Ph.D. | Head of the Laboratory of Structural Biology and Cell Signaling, Institute of Microbiology CAS at BIOCEV; RNDr. Petr Pompach, Ph.D. | Managing Director of AffiPro; Ing. Jiří Hašek, CSc. | Director of the Institute of Microbiology CAS." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_MBU_Mikrobiologicky_ustav_AV_CR_vstupuje_do_biotechnologicke_spolecnosti_Affi_Pro_pomuze_to_vyvoji_novych_leciv_2_6aefdabcd5.jpg 173w," sizes="100vw" width="1536" height="1384">AffiPro has experienced fast organic growth of its protein reactors and protein chips product lines and is currently expanding its unique portfolio of products for basic research, healthcare, and the biotechnology and pharmaceutical industries. The combination of the Academy of Sciences’ strong research portfolio with the agility of a&nbsp;small start-up company creates a&nbsp;strong platform for innovation, future technology transfer, and industrial partnerships. AffiPro’s research, development, and production facilities are located in Vestec near Prague, within the STAR science and technology cluster.“I would like to thank everyone involved in the commercialization of the outputs of our institute’s activities. This is the first time in its history that IMIC CAS owns a&nbsp;share in a&nbsp;spin-off company. The AffiPro’s successful development in recent years and unique plans provide a&nbsp;solid foundation for continued collaboration between our institute and the company. I&nbsp;believe this is a&nbsp;logical step that will benefit both parties and enhance the competitiveness of the Czech biotechnology industry,” says Jiří Hašek, Director of the Institute of Microbiology of the CAS.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/MBU_Mikrobiologicky_ustav_AV_CR_vstupuje_do_biotechnologicke_spolecnosti_Affi_Pro_pomuze_to_vyvoji_novych_leciv_75c7d1eeaa.jpg" alt="MBU: Institute of Microbiology Enters Biotech Company AffiPro:&nbsp;AffiPro s.r.o. specializes in the development and distribution of enzymatic columns, robotic devices for hydrogen-deuterium exchange (pictured), and functionalized surfaces for clinical applications." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_MBU_Mikrobiologicky_ustav_AV_CR_vstupuje_do_biotechnologicke_spolecnosti_Affi_Pro_pomuze_to_vyvoji_novych_leciv_75c7d1eeaa.jpg 221w," sizes="100vw" width="1536" height="1086"><blockquote>Source: Press Release of IMIC CASMore information at: <a target="_blank" rel="noopener noreferrer" href="http://www.affipro.cz">www.affipro.cz</a> | <a target="_blank" rel="noopener noreferrer" href="http://www.mbu.cas.cz">www.mbu.cas.cz </a>| <a target="_blank" rel="noopener noreferrer" href="http://www.biocev.eu">www.biocev.eu</a> | <a target="_blank" rel="noopener noreferrer" href="http://www.star-cluster.cz">www.star-cluster.cz</a></blockquote>

Institute of Microbiology Enters Biotech Company AffiPro

Article

Product

Water

Science and research

Video

The Czech Academy of Sciences (CAS) was established by Act No. 283/1992 Coll. as the Czech successor of the former Czechoslovak Academy of Sciences. It is set up as a complex of 54 public research institutions.

Akademie věd České republiky

For more than 40 years, ALS has provided testing and technical solutions to clients all over the world in a wide range of industries. We have built our global reputation by embracing the latest technologies and innovative methodologies to deliver high quality testing services to clients. ALS is able to leverage a multifaceted international team while remaining agile enough to provide local expertise and personalized solutions to every one of our clients.

ALS Czech Republic

Organomation, founded in 1959, designs and manufactures high-quality nitrogen evaporators and extraction systems. Known for innovation and durability, their lab instruments are used globally for efficient sample preparation with strong customer support.

Organomation

Separation Science

Metrohm

Merck

Mettler-Toledo

C&EN

Karl Fischer (KF) titration is renowned for its rapid and precise measurement of water content in a wide variety of samples.
Understanding the factors that can impact the accuracy of your Karl Fischer titration process is crucial for ensuring optimal results.
Join us for an in-depth webinar that will delve into the critical factors affecting the Karl Fischer titration process and provide a comprehensive overview from start to finish. Participants will gain insights into essential procedures such as titer determination and explore critical applications.
This session is designed to enhance your understanding and improve the precision of your titration techniques.
<h4>Program Overview</h4>
<ul>
<li>Exploring the Components of a Volumetric Karl Fischer Titration Apparatus: Gain a detailed understanding of each element in the apparatus to enhance your practical knowledge.
</li>
<li>Introduction to Karl Fischer Reagents &amp; Standards: Familiarize yourself with the variety of reagents &amp; standards used in Karl Fischer titration and their specific applications.
</li>
<li>The Importance of Titer Determination: Learn why accurate titer determination is crucial for reliable results and discover the best practices for conducting it effectively.
</li>
<li>Analyzing Challenging Samples: Delve into practical examples that demonstrate how to handle and accurately analyze complex samples.
</li>
<li>Innovations in Titration Technology: Learn about our advanced titration technology that utilizes SmartChemicals to seamlessly transfer data to the Karl Fischer titrator.
</li>
</ul>
<blockquote>
Presenter: Bettina Straub-Jubb (Global Product Manager, Karl Fischer Titration at the Life Science Business of Merck KGaA, Darmstadt, Germany)
</blockquote>
<blockquote>
Bettina is the Global Product Manager for Karl Fischer titration and general titration within the Analytical Essentials team at Merck KGaA, Darmstadt, Germany. She has over 20 years of experience in various facets of titration, including Karl Fischer titration, instrumental analysis reagents, and reference materials, contributing significant expertise to her position. Bettina is deeply familiar with all steps of the titration process and collaborates closely with the application laboratories and R&amp;D department to continually enhance titration methodologies. She holds a degree in Chemical Technology from the Darmstadt University of Applied Sciences, Germany, and completed an apprenticeship as a medical technical laboratory assistant at the Medical Technical Academy in Esslingen, Germany.
</blockquote>
<blockquote>
Presenter: Thomas Hitz (Application Chemist, METTLER TOLEDO)
</blockquote>
<blockquote>
Thomas currently serves as a technical advisor for product development at METTLER TOLEDO, Nänikon, Switzerland. With over 15 years of experience in application development, sales, and customer training, he provides expert support for complex automation solutions in both general and Karl Fischer titration. He holds a degree in biochemistry from the University of Zürich and completed his PhD in 2003 at the Swiss Federal Institute of Technology Zurich in the Department of Material Sciences.
</blockquote>

Mettler Toledo: Optimize Your Volumetric Karl Fischer Titration

Optimize Your Volumetric Karl Fischer Titration

Critical factors affecting the Karl Fischer titration process and a comprehensive overview from start to finish.

Automatic titration plays a crucial role in ensuring precise and consistent results in various industry and research sectors, directly impacting the quality and safety of products we use daily. Despite the automation of the titration process itself, many manual steps still require an analyst&#39;s full-time attention. By optimizing titration procedures and using advanced instruments and accessories, it is possible to automate auxiliary tasks such as pipetting, diluting, and adding reagents. This optimization also enables the system to make decisions, such as whether to proceed with an analysis or take specific actions based on the results.
In this webinar, Monica Laurel, Analytical Manager at Dow Chemical, will share success stories of titration methodology optimization carried out by her and her team across various Dow Chemical units during her 20-year career. Eduardo Simões, Product Specialist for Titration at Metrohm USA, will demonstrate how automated systems can systematically reduce human error, ensure compliance with laboratory safety regulations, and enhance the accuracy and reproducibility of results.
Don&#39;t miss the live Q&amp;A at the end, where Monica and Eduardo will answer all your questions.
Please plan to attend if you:
<ul>
<li>Want to learn about titration procedure optimization</li>
<li>Are interested in reducing exposure to chemicals during titration analysis</li>
<li>Would like to understand how advanced software functions can monitor results and help with decision making</li>
<li>Are interested in improving the consistency of your titration results</li>
</ul>
Key Learning Points
<ul>
<li>Understand different ways to optimize your current titration methodology</li>
<li>Learn how a sample robot can help save analyst time by automating manual steps</li>
<li>Learn advanced software functions for better programming and monitoring data</li>
</ul>
<blockquote>
Presenter: Monica Laurel (Analytical Manager, Dow Chemical)
</blockquote>
<blockquote>
Monica Laurel is a Research Scientist with DOW Chemical in Freeport, Texas. She received her BS in Chemistry from the University of Texas at Austin. Monica joined Union Carbide in St. Charles, LA in 1995 as a process chemist. In 2004 she moved back to Texas and joined the Analytical Sciences group at DOW Chemical and began work in the Inorganic Lab focusing on titration technology. She has 20 years experience in numerous titration and Karl Fischer methods and techniques where she has worked to improve and automate titrations for implementing in DOW’s quality labs.
</blockquote>
<blockquote>
Presenter: Eduardo Simões (Titration Product Specialist, Metrohm USA)
</blockquote>
<blockquote>
Eduardo Simoes, MSc is the Titration Product Specialist at Metrohm USA in Riverview, Florida. He received his bachelor and masters in analytical chemistry at the University of Campinas, Brazil. Over the last 21 years with Metrohm, he specialized in potentiometry and electroanalysis, gaining extensive field experience in applications and instrument installations, technical support &amp; training.
</blockquote>

Metrohm: Real-World Titration Optimization: Advanced Techniques for Improved Results

Real-World Titration Optimization: Advanced Techniques for Improved Results

We will share success stories of titration methodology optimization and demonstrate how automated systems can systematically reduce human error.

Titration: Advanced Techniques for Improved Results

Titration is generally considered a fairly simple analytical technique. But what do you do, if your titration results are not what they should be? Enter Robert Tobler, Senior Application Specialist Titration at Metrohm International Headquarters!In his webinar on September 18, Robert will show you what typical errors can occur during a titration – and how to avoid or remedy them. Focusing on troubleshooting, Robert will cover everything from the electrode to the setup of your titrator to titration parameters and calculation of &nbsp; the result. The following questions give you an idea of the scope and practical relevance of this webinar:<ul><li>How important is calibration?</li><li>Do I really need to stir the titration solution – and why?</li><li>What do I do, if several equivalence points are detected – or none at all</li><li>How to clean the electrode properly?</li></ul>These questions and many more will be answered step by step so that everyone can follow and understand. During a Q&amp;A session at the end of the webinar, you can ask Robert any question you may have about titration.<blockquote>Presenter: Robert Tobler (Senior Application Specialist Titration, Metrohm International Headquarters)After his apprenticeship as a chemical laboratory technician and further training as a biomedical analyst, Robert Tobler studied chemistry at the Zurich University of Applied Science in Waedenswil, Switzerland. He joined Metrohm in 2015 as an application specialist titration. Since then, Robert has become an expert in applied titration sharing his expertise through the global network of Metrohm subsidiaries.</blockquote>

Metrohm: Troubleshooting titration: essential know-how for quality results

Troubleshooting titration: essential know-how for quality results

What typical errors can occur during a titration – and how to avoid or remedy them.

Troubleshooting titration: essential know-how for quality

Key takeaways from this webinar include:<ul><li>Understanding surfactants and their significance</li><li>How to accurately measure cationic, anionic, and non-ionic surfactants using potentiometric titration</li><li>The distinction between aqueous surfactant titration and two-phase surfactant titration, and when to use each method</li><li>How two-phase surfactant titration serves as a viable alternative to the widely used Epton Titration</li><li>Choosing the right potentiometric sensor for specific titrations</li></ul><blockquote>Presenter: Mona Wagner (Application Specialist Titration, to learn how to analyze surfactants by automatic potentiometric titration)</blockquote>

Metrohm: Best practice for surfactant analysis by potentiometric titration

Best practice for surfactant analysis by potentiometric titration

How to accurately measure cationic, anionic, and non-ionic surfactants using potentiometric titration.

Best practice for surfactant analysis

Dive into the future of Karl Fischer titration in this engaging webinar, where we will unveil the cutting-edge advancements and emerging trends shaping this critical analytical field.This session is specifically designed to highlight the innovative features of the EVA KF Titrators, which represent the forefront of titration technology. We will explore the integration of advanced technologies such as the Fast-Forecasting Amperometric (FFA™) Control Algorithm, which enhances the speed and reliability of water content determination, drastically reducing titration times without compromising result quality. Learn about the advanced drift management techniques that ensure consistent and reliable measurements, critical for industries where accuracy is paramount.Participants will also gain insight into how these technologies are being applied across various sectors, driving improvements in everything from pharmaceuticals to food and chemical manufacturing. The session will cover how the flexibility of the EVA KF titrators enables laboratories to adapt quickly to new regulations and testing requirements, supporting sustained compliance and operational excellence.<h4>Program Overview</h4><ul><li>Technological Innovations: Uncover the cutting-edge advancements in Karl Fischer titration, including the integration of the Fast-Forecasting Amperometric (FFA™) Control Algorithm.</li><li>Precision and Efficiency: Learn about new drift management techniques that enhance the accuracy and reliability of measurements, crucial for industries where precision is paramount.</li><li>Adaptability to Regulations: Explore how EVA KF Titrators' flexibility aids laboratories in swiftly adapting to new regulations and maintaining operational excellence.</li></ul><blockquote>Presenter: Erik GublerA Global Product Manager at METTER TOLEDO in Switzerland, specializing in analytical instruments. He holds a master's degree in chemistry from the Swiss Federal Institute of Technology (ETH Zurich). He has been an integral part of developing the next generation of automated titrators and software. His chemistry expertise and product insight ensure the continuous advancement and reliability of METTLER TOLEDO’s titrators across various industries.Presenter:&nbsp;Lukas FritscheAn Application Specialist at METTLER TOLEDO in Switzerland, specializing in titration technology. With a Ph.D. in chemistry from ETH Zurich, Lukas plays a pivotal role at METTLER TOLEDO in advancing application development and enhancing instrument capabilities. His work supports the continuous innovation and reliability of the company’s analytical instruments.</blockquote>

Mettler Toledo: The Future of Karl Fischer Titration

The Future of Karl Fischer Titration

The innovative features of the EVA KF Titrators, which represent the forefront of titration technology.

<h4>Eight Webinars and a Roundtable with Experts from Merck</h4>Analytical Excellence Week' is organized to empower professionals in the field of analytical chemistry. Over the course of eight insightful sessions, industry experts will share their knowledge and best practices to streamline your analytical workflows and enhance your efficiency.From understanding quality grades in inorganics and solvents to exploring sustainable practices in the lab, each webinar covers essential topics that will enhance your analytical capabilities. Learn how to optimize your Karl Fischer titration, achieve precision in PFAS testing, and gain troubleshooting tips for LC-MS to effectively address common challenges and improve your laboratory results.The sessions will also address critical aspects of safety and sustainability, ensuring you are well-equipped to handle hazardous chemicals responsibly while making strides toward greener laboratory practices.This is an invaluable opportunity to gain insights that can significantly optimize your analytical processes. Don’t miss your chance to elevate your expertise and contribute to a more efficient and sustainable future in analytical workflows.Each session is specifically designed to address essential topics that directly impact your daily practices, making it relevant for all professionals working in a chemical analysis laboratory.<h3>Day 3: Wednesday, 12 February</h3><h4>Optimize Your Karl Fischer Titration: Expert Insights for Enhanced Results</h4>With Karl Fischer titration, you can quickly and accurately determine water content in a wide variety of samples. The accuracy of the results depends on a well-defined titration application process. Pre-titration and titer determination are essential for obtaining correct results. The main challenges arise from samples that do not dissolve or that undergo side reactions in standard solvents. Learn the measures you can take to release water from such samples and the preferred methods to use—volumetry or coulometry. Additionally, discover how digital data transfer enables efficient, fast, and secure data integration with your titrator software.By attending this webinar, you will learn:<ul><li>The key steps in the Karl Fischer titration process</li><li>The importance of accurate pre-titration and regular titer determination</li><li>Effective methods for completely releasing water from your samples</li><li>How digital data transfer can streamline and secure your daily data transfer and documentation</li><li>Practical tips for overcoming daily challenges in Karl Fischer Titration</li></ul>Who should attend: This webinar will be especially valuable for individuals involved in developing Karl Fischer titration applications, performing titrations in QC labs or during in-process control, and those responsible for assessing and enhancing processes. This includes lab technicians, lab managers, and quality assurance managers across various segments.<blockquote>Presenter: Bettina Straub-Jubb, (Global Product Manager Analytical Technologies, Merck)</blockquote><h4>Beyond Safety Standards – Best Practices for Safe Handling of Hazardous Chemicals</h4>This webinar illustrates the role of safety in the lab as well as the challenges that can occur while handling hazardous goods in the daily lab work and how to overcome these challenges. Rules and regulations for daily handling of hazardous goods are discussed, and options are shown on how to improve daily processes regarding personal safety. The presentation focuses on the prevention of accidents, emergency help in case of chemical spillages, and safe and reliable cleaning of lab equipment. Join the webinar for an informative overview of safety solutions and tools for maximum safety and reliability in your lab.By attending this webinar, you will learn:<ul><li>Basic safety risks and rules for daily handling of hazardous goods and options for how to improve daily processes regarding personal safety</li><li>Packaging-related safety topics</li><li>Practical guidelines for handling hazardous chemicals in case of spillages</li><li>Lab equipment cleaning know-how for reliable analytical results</li></ul>Who should attend: Staff and head of chemical labs (e.g. quality control, research), as well as safety managers/safety engineers for chemical laboratories.<blockquote>Presenter: Annett Schneider, (Global Product Manager and Lead Expert for Safety Products and Essentials, Merck)&nbsp;</blockquote>

Merck: Webinar Series & Expert Roundtable

Webinar Series & Expert Roundtable (Day 3)

Part 1: Optimize Your Karl Fischer Titration and Part 2: Beyond Safety Standards – Best Practices for Safe Handling of Hazardous Chemicals

<h4>Eight Webinars and a Roundtable with Experts from Merck</h4>Analytical Excellence Week' is organized to empower professionals in the field of analytical chemistry. Over the course of eight insightful sessions, industry experts will share their knowledge and best practices to streamline your analytical workflows and enhance your efficiency.From understanding quality grades in inorganics and solvents to exploring sustainable practices in the lab, each webinar covers essential topics that will enhance your analytical capabilities. Learn how to optimize your Karl Fischer titration, achieve precision in PFAS testing, and gain troubleshooting tips for LC-MS to effectively address common challenges and improve your laboratory results.The sessions will also address critical aspects of safety and sustainability, ensuring you are well-equipped to handle hazardous chemicals responsibly while making strides toward greener laboratory practices.This is an invaluable opportunity to gain insights that can significantly optimize your analytical processes. Don’t miss your chance to elevate your expertise and contribute to a more efficient and sustainable future in analytical workflows.Each session is specifically designed to address essential topics that directly impact your daily practices, making it relevant for all professionals working in a chemical analysis laboratory.<h3>Day 5: Friday, 14 February</h3><h4>Roundtable Expert Discussion</h4>Our experts will come together to discuss the best practices to streamline your analytical workflows and enhance your efficiency. We will cover some questions asked during the week, as well as answer new questions during the roundtable discussion. &nbsp;<blockquote>Presenter: Ernie Hillier (Independent Pharmaceutical Consultant, EJH Consulting)</blockquote>

Webinar Series & Expert Roundtable (Day 5)

Webinar Series & Expert Roundtable (Day 5) - Roundtable Expert Discussion

<h5>By attending this discussion, you will:</h5><ul><li>Discover how automated control algorithms enhance precision and reduce titration times without compromising accuracy.</li><li>Understand how advanced drift management tools ensure reliable results, even in demanding conditions.</li><li>Explore how modern titration systems address safety and sustainability goals with features such as remote operation and support for greener solvents.</li></ul><h5>Event Overview</h5>For nearly a century, Karl Fischer titration has been the trusted method for determining water content in products ranging from pharmaceuticals to processed snacks. However, even reliable techniques face challenges. For example, antibiotics can be difficult to analyze due to their limited solubility in conventional solvents, often requiring additional heating steps to ensure accurate measurements. Environmental factors, such as humidity, can further complicate workflows by introducing drift and reducing precision.Join us for an expert discussion exploring how the latest innovations in Karl Fischer titration technology tackle these issues head-on. Panelists Nicolas Monney (Application Chemist, Mettler-Toledo) and Matteo Stefanoni (Senior Scientist, Mettler-Toledo) will answer questions related to advancements such as high-resolution sensors, low-dead-volume burets, and modular designs that improve accuracy, safety, and workflow efficiency. Learn how the EVA KF Titrator’s Fast Feedback Algorithm redefines titration workflows by adapting in real time to reaction conditions.<h5>Who Should Attend:</h5><ul><li>Scientists, lab managers, and analysts working in water determination across industries, including pharmaceuticals, food, biopharma, and materials science.</li><li>Professionals seeking practical solutions to improve accuracy, efficiency, and reproducibility in Karl Fischer titration workflows.</li><li>Anyone facing challenges with complex samples, drift, or evolving regulatory requirements in moisture analysis.</li></ul><h5>Share Your Challenges Across Industries</h5>Water determination plays a pivotal role in advancing quality and innovation. Do you struggle with reactive compounds, complex sample matrices, or meeting regulatory demands? This event offers the chance to have your specific questions addressed by experts.Submit your questions through the webinar registration form, and our panel will address selected challenges during the broadcast.<blockquote>Presenter: Nicolas Monney (Application chemist, Mettler-Toledo)Nicolas Monney holds a Ph.D. in Physical Chemistry. His research focused on studying electron transfer through proteins using low-temperature spectroscopy and ab-initio simulations.Nicolas began his career at Mettler-Toledo nearly ten years ago, taking on the role of Applications Specialist for Titration. In this role, he develops innovative titration applications and collaborates closely with the R&amp;D department to facilitate the development of new products. Additionally, he supports the sales force of Mettler-Toledo and its partners on titration projects worldwidePresenter: Matteo Stefanoni (Senior Scientist, Mettler-Toledo International)Matteo is a scientist with a strong academic background and experience in the fields of chemistry and material science. He earned his Master’s degree in Chemistry from the University of Milano and a PhD from ETH Zürich, focusing on electrochemistry. After completing his doctoral studies, Matteo spent two years as a postdoctoral researcher, further enhancing his expertise in the field. Currently, Matteo serves as a Senior Scientist at Mettler-Toledo, where he has spent the last five years developing advanced control algorithms for automatic titration instruments. Notably, he has dedicated four of those years to developing an innovative model-based control algorithm for Karl Fischer titration analysis, significantly improving the efficiency of this analytical technique.</blockquote>

Separation Science: Rethinking Karl Fischer Titration: How Smarter Algorithms Tackle Complex Water Determinations

Rethinking Karl Fischer Titration: How Smarter Algorithms Tackle Complex Water Determinations

Join us for an expert discussion exploring how the latest innovations in Karl Fischer titration technology tackle issues.

KF Titration: Smarter Algorithms Tackle Water Determinations

Analytical laboratories face continuous pressure to handle increasing sample volumes while delivering rapid, high-quality results. Quality managers and analysts must balance competing demands: maintaining precision and accuracy, meeting regulatory requirements, reducing environmental impact, and optimizing costs. These challenges are particularly acute in moisture analysis, where traditional methods often require significant time and resources, while inconsistencies between operators can impact reliability.Join industry experts as they explore modern approaches to moisture analysis in chemical, polymer, and petrochemical environments. This educational session will examine how laboratories can overcome common analytical challenges through the integration of complementary techniques. Through real-world examples and industry case studies, we'll discuss how combining reference methods with spectroscopic techniques can enhance laboratory efficiency. The session will conclude with insights from Lubrizol's experience in modernizing their analytical workflows, offering practical takeaways for laboratories looking to improve their testing procedures.<h5>Key Learning Objectives:</h5><ul><li>Fundamentals of Karl Fischer and NIR analysis</li><li>Strategies for workflow optimization and automation</li><li>Practical considerations for implementing new analytical methods</li><li>How OMNIS reduces waste while increasing speed and accuracy</li></ul><h5>Who Should Attend:</h5><ul><li>Analytical lab managers</li><li>Quality control or assurance mangers/directors</li><li>Process engineers or production managers</li><li>Anyone interested in learning about more efficient ways to do moisture analysis</li></ul><blockquote>Presenter: Bridget Brassell (Quality Assurance Improvement Manager, Lubrizol)Presenter:&nbsp;Eduardo Simoes, MSc (Titration Product Specialist, Metrohm USA)Presenter:&nbsp;Lenzi Williams, PhD (Spectroscopy Product Specialist, Metrohm USA)Presenter:&nbsp;Alexandra Taylor (Contributing Editor, C&amp;EN Media Group)</blockquote>

C&EN: From Challenges to Solutions: Revolutionizing Moisture Analysis with NIR and Titration

From Challenges to Solutions: Revolutionizing Moisture Analysis with NIR and Titration

Join industry experts as they explore modern approaches to moisture analysis in chemical, polymer, and petrochemical environments. 

Revolutionizing Moisture Analysis with NIR and Titration

Titration is a classic yet evolving technique. Whether you're tackling weak acids, complex matrices or low concentrations, modern titration methods offer smarter, faster solutions. In this educational webinar, we’ll explore how new approaches to titration are used to open doors in sectors like batteries, semiconductors and specialty chemicals. Conductometric titration for precise determination of weak acids and halides and thermometric titration for high-concentration acid mixture samples, are just two examples that show how titration has evolved over time.Join Eduardo Simões, Product Specialist for Titration, and Scott Segro, Senior Scientist, as they showcase the latest sensors, share real-world case studies and explain how flexible, integrated systems can transform your lab’s productivity. From customizing workflows to solving tough applications, this session is packed with practical insights. Stick around for a live Q&amp;A to ask your toughest titration questions, our experts are ready for them.Key Learning Objectives:<ul><li>Understand how conductometric and thermometric titrations work, and when to use them</li><li>Explore new sensors and their applications in challenging or emerging sample types</li><li>Learn how to customize titration workflows, including integration with other analytical techniques</li></ul>Who Should Attend:<ul><li>Those who want to stay up to date on the latest in automatic titration techniques and sensors</li><li>If you want to learn novel applications applied for emerging technologies</li><li>Those interested in discovering customization possibilities with titration including low-volume analysis and integration with other techniques</li></ul><blockquote>Presenter: Eduardo Simões, MSc (Titration Product Specialist, Metrohm USA)Presenter: Scott Segro, PhD (Senior Scientist, Metrohm USA)</blockquote>

LCMS webinars focusing on Titration | LabRulez LCMS

What’s New in Titration: New Techniques, Applications and Integration