<div><div><div>Scientists at IOCB Prague have developed a breakthrough technology that streamlines aptamer development. The new method integrates several biochemical and bioinformatics steps and paves the way for new diagnostic and therapeutic applications. Ongoing applications include wearable sensors that monitor selected biomarkers in real time and provide early warnings of impending health complications. The findings were published in Nature Communications.</div></div><div>Aptamers are short DNA or RNA strands that can recognize and bind to a specific target molecule with high precision. Similar to antibodies, they can be used to detect these molecules or modulate their activity. Unlike antibodies, they are much more stable, can be produced synthetically, and can be chemically modified to achieve the desired properties. As a result, they can offer capabilities that cannot be achieved with antibodies.</div><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/UOCHB_Nova_technologie_inovuje_vyvoj_aptameru_syntetickych_alternativ_protilatek_2_81e99b9900.jpg" alt="IOCHB Prague: New technology streamlines the development of aptamers, synthetic alternatives to antibodies: Chemically modified DNA aptamer bound to the target protein." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_UOCHB_Nova_technologie_inovuje_vyvoj_aptameru_syntetickych_alternativ_protilatek_2_81e99b9900.jpg 228w," sizes="100vw" width="1343" height="916">As demand grows for accurate and rapid diagnostic tools, aptamers are often better suited to these applications than antibodies. However, developing aptamers is both experimentally demanding and time-consuming. A team of scientists from IOCB Prague, led by Dr. Marek Ondruš and <a target="_blank" rel="noopener noreferrer" href="https://hocek.group.uochb.cz/en">Prof. Michal Hocek</a>, has now developed a technology that significantly shortens the development process.“Developing an aptamer is often like looking for a needle in a haystack. Among trillions of different DNA sequences, we search for the one that binds strongly and specifically to a target molecule. Our new approach first screen for ‘aptamer families’ – hundreds of related sequences – and then identify the best-performing member of the family. This approach can reduce development time from several months to only a few days,” says Marek Ondruš.<blockquote>Video:<a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/watch?v=_3zXUeVMugU"> New technology streamlines the development of aptamers, synthetic alternatives to antibodies&nbsp;</a></blockquote>The team has also expanded the potential applications of aptamers by chemically modifying their building blocks. For example, introducing functional groups similar to those found naturally in amino acids allows the resulting molecules to combine the advantages of both DNA and antibodies: Their sequence is encoded by the order of nucleotides in DNA, while the attached chemical modifications greatly expand their ability to recognize biologically relevant targets and mimic interactions between proteins that are underlying many biological processes.The researchers demonstrated the potential of this new method using the human insulin receptor, a key protein that regulates blood sugar levels. They developed an aptamer that specifically binds to the receptor and elucidated the molecular basis of this interaction using cryo-electron microscopy. “We have shown that chemically introduced functional groups play a crucial role not only in target recognition and formation of the aptamer–protein complex, but also in stabilizing the DNA aptamer’s structure. Our findings provide new insights into how chemically modified nucleic acids can mimic key properties of proteins,” says Marek Ondruš.In the future, the technology could complement – or, in some applications, even replace – antibody-based diagnostic tools. Researchers are collaborating with <a target="_blank" rel="noopener noreferrer" href="http://iocbtech.cz/">IOCB Tech</a> on its further development, as the company helps to bring discoveries from IOCB Prague into practical applications.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/UOCHB_Nova_technologie_inovuje_vyvoj_aptameru_syntetickych_alternativ_protilatek_9694c21671.jpg" alt="IOCHB Prague/Tomáš Belloň: New technology streamlines the development of aptamers, synthetic alternatives to antibodies: Dr. Marek Ondruš, first author of the study, and Prof. Michal Hocek, head of the Bioorganic and Medicinal Chemistry of Nucleic Acids research group at IOCB Prague." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_UOCHB_Nova_technologie_inovuje_vyvoj_aptameru_syntetickych_alternativ_protilatek_9694c21671.jpg 234w," sizes="100vw" width="2000" height="1335"><blockquote><h4>Original article</h4><h4><a target="_blank" rel="noopener noreferrer" href="https://www.nature.com/articles/s41467-026-73676-y#citeas">Expedient single-round selection of hyper-modified aptamer targeting insulin receptor from over-represented dually nucleobase-modified DNA libraries</a></h4>ablo Alberto Franco-Urquijo, Marek Ondruš, Jaroslav Kurfürst, Jana Škerlová, Irena Selicharová, Lucie Mužíková Čechová, Hana Šváchová, Alena Semerádtová, Anatolij Filimoněnko, Adéla Fejfarová, Jiří Homola, Tomáš Kouba &amp; Michal HocekNat. Commun., 2026<a target="_blank" rel="noopener noreferrer" href="https://doi.org/10.1038/s41467-026-73676-y">https://doi.org/10.1038/s41467-026-73676-y</a>&nbsp;<h6>licenced under <a target="_blank" rel="noopener noreferrer" href="https://creativecommons.org/licenses/by/4.0/">CC-BY 4.0</a></h6></blockquote><h4>Abstract</h4>Discovery of functional nucleic acids from randomized libraries typically relies on multiple, time-consuming iterative rounds of in vitro selection with low success rate. Here, we present a single-round selection strategy for rapid screening of multiple over-represented nucleobase-modified DNA libraries and various selection conditions, capable of identifying high-affinity modified aptamers. Double partition followed by amplification of eluted sequences, NGS analysis and clustering provides fast identification of aptamer candidates. Screening of modified DNA libraries containing modified adenine and uracil nucleotides bearing hydrophobic aromatic phenyl and indole moieties results in development of an aptamer binding human insulin receptor with sub-nanomolar affinity and exquisite specificity. Cryo-EM structure reveals the importance of each aromatic modification, either in stabilizing the secondary structure or facilitating interactions with the protein surface. This approach addresses the main drawbacks of aptamer selection and has potential for high-throughput screening and accelerating the development of next-generation aptamers for diagnostics or therapeutics.</div>

New technology streamlines the development of aptamers, synthetic alternatives to antibodies

Clarity 10.2 expands instrument control capabilities with new control modules and updates the MS extension to help you work more efficiently.<h4><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/999">Clarity</a> 10.2 highlights</h4><ul><li>New and updated control modules</li><li>Improved MS data import and export</li><li>Obsolete hardware support ended</li></ul><h4>Instrument control modules</h4>Clarity 10.2 introduces new instrument control modules from Annuo (AS-3117, FAS-3823) and updated instrument controls form Sykam and Ecom.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_Instrument_control_modules_5de26782b0.jpg" alt="DataApex: Instrument control modules" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Data_Apex_Instrument_control_modules_5de26782b0.jpg 228w," sizes="100vw" width="380" height="260"><h4>MS data import/export improvements</h4>Clarity improves MS data exchange, especially for *.cdf files. MS instruments now support export and import of multiple spectral data and non-spectral signal data in the same CDF file. Import also better handles uniform sampling information, m/z Step values, scale factors, and file names with non-ASCII characters. Exporting individual chromatogram signals from MS instruments is now available through a separate Export Chromatogram dialog.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_MS_data_import_export_improvements_a7967a4020.jpg" alt="DataApex: MS data import-export improvements" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Data_Apex_MS_data_import_export_improvements_a7967a4020.jpg 228w," sizes="100vw" width="378" height="259"><h4>Obsolete hardware support terminated</h4>Due to changes in Windows driver security requirements, this update discontinues support for obsolete hardware, including INT7, INT9, U-PAD, U-PAD2, and CB20.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_Obsolete_hardware_support_terminated_24d9329419.jpg" alt="DataApex: Obsolete hardware support terminated" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Data_Apex_Obsolete_hardware_support_terminated_24d9329419.jpg 228w," sizes="100vw" width="378" height="259"><blockquote>Explore the complete list of all changes, fixes, and additions in version 10.2.👉<a target="_blank" rel="noopener noreferrer" href="https://www.dataapex.com/version_history?product=1">See the complete changelog&nbsp;</a></blockquote>

Clarity Chromatography Software 10.2 released!

🎤Dr. Leigh Terry (University of Alabama)In this episode of Concentrating on Chromatography, we sit down with Dr. Leigh Terry from the University of Alabama to explore one of the biggest challenges in environmental analysis today: understanding—and accurately measuring—PFAS in water systems.While most regulatory methods focus on a small number of compounds like PFOA and PFOS, there may be thousands of PFAS compounds in the environment—and much of that burden goes undetected.<h4>In this episode, we cover:</h4><ul><li>Why PFAS are called “forever chemicals” (and why that label is evolving)</li><li>The limitations of targeted LC-MS/MS methods</li><li>What the fluorine mass balance problem reveals about PFAS destruction</li><li>How combustion ion chromatography (CIC) helps measure total organofluorine</li><li>Why “99.99% removal” doesn’t always mean what you think</li><li>Where PFAS actually end up in wastewater treatment systems</li><li>The most effective technologies for PFAS removal today</li><li>Why drinking water may only account for ~20% of total PFAS exposure</li></ul><h4>Key Insight:</h4>Even when analyzing dozens of PFAS compounds, researchers may only be capturing a small fraction of total organic fluorine—raising major questions about how we monitor and regulate these contaminants.<h3>Video Transcription</h3>In this episode of Concentrating on Chromatography, Dr. Leigh Terry discusses PFAS contamination in drinking water, the analytical challenges associated with measuring these compounds, current treatment technologies, and future directions for monitoring and regulation. The conversation highlights how analytical chemistry, environmental engineering, and public health intersect in addressing one of today's most discussed classes of emerging contaminants.<h4>Understanding PFAS and Their Significance</h4><h5>The University of Alabama Water Quality Research Center</h5>Dr. Leigh Terry is part of the University of Alabama's Center for Water Quality Research. The center operates an analytical laboratory focused on drinking water quality and the detection of contaminants at extremely low concentrations.The laboratory specializes in:<ul><li>Drinking water analysis</li><li>Organic contaminants</li><li>Emerging contaminants</li><li>PFAS monitoring</li><li>Water quality research</li></ul>Their work supports both research initiatives and practical solutions for water utilities and environmental agencies.<h4>Why Focus on PFAS?</h4>Although PFAS compounds have existed since the 1940s, public awareness has increased dramatically only in recent years.According to Dr. Terry, several factors contributed to the rapid growth of PFAS research:<ul><li>Increased media attention</li><li>New regulatory initiatives</li><li>Growing evidence of human exposure</li><li>Expanding research opportunities</li><li>Greater understanding of potential health risks</li></ul>PFAS are not new contaminants. Rather, society is only beginning to understand their prevalence in the environment and their potential impacts on human health.<h4>The Development of Standardized PFAS Methods</h4>One major advancement in PFAS analysis has been the development of standardized EPA methods.These methods allow:<ul><li>Consistent testing procedures</li><li>Comparable results between laboratories</li><li>Regulatory monitoring</li><li>Reliable data interpretation</li></ul>Dr. Terry notes that many of these standardized approaches began appearing around 2018–2019, providing a common framework for analytical laboratories and researchers.<h4>How Large Is the PFAS Universe?</h4>Many people are familiar with PFOA and PFOS, two of the most heavily studied PFAS compounds. However, these represent only a small fraction of the broader PFAS family.PFOA and PFOS are often referred to as:<ul><li>Legacy PFAS compounds</li><li>Original PFAS contaminants</li><li>Early commercial PFAS chemicals</li></ul>The challenge is that even minor modifications to molecular structure create entirely new PFAS compounds.Researchers estimate:<ul><li>Thousands of PFAS compounds exist</li><li>Some estimates exceed 10,000 compounds</li><li>Exact numbers depend on how PFAS are defined</li></ul>Scientific debate continues regarding classification and definition, making precise counting difficult.<h4>Why PFAS Are Called "Forever Chemicals"</h4>Dr. Terry notes that the phrase "forever chemicals" has become widely used, although she suggests the terminology could benefit from rebranding.PFAS persistence results from two key chemical properties.<h5>1. Amphiphilic Structure</h5>PFAS molecules contain:<ul><li>A water-loving (hydrophilic) head group</li><li>A water-repelling (hydrophobic) fluorinated tail</li></ul>This unusual combination allows PFAS to partition between:<ul><li>Water</li><li>Solids</li><li>Air-water interfaces</li><li>Foam</li></ul>Unlike many organic compounds, PFAS can interact effectively with multiple environmental phases.<h5>2. Extremely Strong Carbon–Fluorine Bonds</h5>The carbon–fluorine bond is among the strongest bonds in organic chemistry.As Dr. Terry explains:<ul><li>Large amounts of energy are required to break these bonds</li><li>Natural degradation processes are often ineffective</li><li>Destruction can require highly aggressive treatment conditions</li></ul>These properties make PFAS extremely persistent in both environmental systems and biological organisms.<h4>Toxicity, Regulations, and Environmental Behavior</h4><h5>Understanding PFAS Toxicity</h5>One of the biggest challenges in PFAS regulation is the incomplete understanding of toxicity.Dr. Terry explains that EPA regulations generally consider three factors:<ul><li>Presence in drinking water sources</li><li>Toxicity to humans</li><li>Availability of practical treatment options</li></ul>While some PFAS compounds are known to be harmful, many others remain insufficiently studied. Furthermore, PFAS often occur as mixtures rather than individual compounds.This creates important scientific questions:<ul><li>What is the toxicity of individual PFAS?</li><li>What is the toxicity of PFAS mixtures?</li><li>How should cumulative exposure be evaluated?</li></ul>These uncertainties continue to drive active research.<h4>What Happens to PFAS in Wastewater Treatment Plants?</h4>PFAS do not behave like many conventional contaminants.Rather than remaining fully dissolved in water, they often accumulate at interfaces such as:<ul><li>Water-solid interfaces</li><li>Water-air interfaces</li><li>Foam layers</li><li>Biological solids</li></ul>As a result:<ul><li>Some PFAS accumulate in biosolids</li><li>Some partition into foam</li><li>Some remain in treated effluent</li></ul>Their distribution depends on wastewater composition and treatment processes.<h4>Regulatory Monitoring and Targeted LC-MS Analysis</h4>Current EPA regulations focus on targeted analysis of specific PFAS compounds.Examples include:<ul><li>PFOA</li><li>PFOS</li></ul>Drinking water regulations currently establish maximum contaminant levels (MCLs) for these compounds at extremely low concentrations.Advantages of targeted LC-MS analysis include:<ul><li>Clearly defined analytes</li><li>Established regulatory limits</li><li>High analytical sensitivity</li><li>Reliable quantitation</li></ul>However, limitations remain:<ul><li>Only a small subset of PFAS is measured</li><li>Many PFAS compounds remain undetected</li><li>Total PFAS burden may be underestimated</li></ul>As Dr. Terry notes, targeted analysis provides only part of the overall picture.<h4>The Fluorine Mass Balance Problem</h4>One of the most important concepts discussed in the interview is fluorine mass balance.When PFAS degrade, fluorinated fragments may remain in the environment.This creates a critical question:Are treatment technologies truly destroying PFAS, or merely transforming them into shorter-chain PFAS compounds?To answer this, researchers perform fluorine mass balance calculations using:<ul><li>Targeted PFAS analysis</li><li>Fluoride measurements</li><li>Total organic fluorine measurements</li></ul>A successful destruction process should ultimately convert PFAS into fluoride ions rather than simply producing smaller PFAS molecules.<h4>Advanced Analysis, Treatment Technologies, and Future Directions</h4><h5>Combining Targeted and Bulk Fluorine Measurements</h5>Dr. Terry's group complements targeted LC-MS analysis with measurements of total organic fluorine.Approaches include:<ul><li>Absorbable Organic Fluorine (AOF)</li><li>Extractable Organic Fluorine (EOF)</li><li>Combustion Ion Chromatography (CIC)</li></ul>In these methods:<ul><li>Organic fluorine is captured</li><li>Samples are combusted</li><li>Released fluoride is quantified</li></ul>This provides insight into total fluorinated content, although contributions may originate from sources beyond PFAS, including pharmaceuticals and consumer products.<h4>Surprising Findings from Combined Analysis</h4>One important finding from wastewater studies was that targeted PFAS measurements accounted for only a small fraction of total organic fluorine.Dr. Terry reports that:<ul><li>Approximately 4% of measured AOF could be explained by targeted PFAS compounds</li><li>The majority of organic fluorine remained unidentified</li></ul>This suggests that environmental fluorine chemistry is considerably more complex than currently represented by routine monitoring programs.<h4>Preventing PFAS Contamination in the Laboratory</h4>PFAS analysis requires exceptionally strict quality control.Dr. Terry's laboratory routinely:<ul><li>Tests every new batch of SPE cartridges</li><li>Tests carbon tubes before use</li><li>Uses DI water blanks</li><li>Verifies consumables labeled as PFAS-free</li><li>Collects field blanks</li><li>Monitors analytical blanks throughout workflows</li></ul>These practices help prevent contamination from laboratory materials and consumables, a common challenge in ultra-trace PFAS analysis.<h4>Current PFAS Treatment Technologies</h4>Three technologies currently dominate PFAS removal in drinking water treatment:<ul><li>Granular Activated Carbon (GAC)</li><li>Ion Exchange Resins</li><li>Reverse Osmosis (RO)</li></ul>Selection depends on:<ul><li>PFAS concentration</li><li>Water quality</li><li>Local operating conditions</li><li>Utility infrastructure</li></ul>Although many emerging technologies are being investigated, these remain the most widely implemented solutions.<h4>Membrane Filtration and Pretreatment</h4>Dr. Terry collaborates with colleagues studying membrane-based PFAS treatment.Her own work focuses on pretreatment through biological filtration.The strategy involves:<ul><li>Removing natural organic matter</li><li>Reducing membrane fouling</li><li>Improving membrane performance</li><li>Extending operational efficiency</li></ul>This integrated approach demonstrates how multiple treatment technologies can work together to improve PFAS removal.<h4>Regional Monitoring Projects</h4>The University of Alabama team participates in EPA-supported monitoring efforts along the Gulf Coast.Their observations indicate:<ul><li>PFAS rarely occur alone</li><li>Multiple PFAS compounds frequently co-occur</li><li>Contamination often originates from identifiable point sources</li></ul>Examples include:<ul><li>Industrial facilities</li><li>Manufacturing operations</li><li>Military installations</li><li>Carpet manufacturing facilities</li></ul>Source identification remains a critical component of environmental monitoring programs.<h4>Future Directions for PFAS Monitoring</h4>Looking ahead, Dr. Terry sees several opportunities for improvement.Desired advances include:<ul><li>In situ monitoring technologies</li><li>Portable detection systems</li><li>Reduced analytical complexity</li><li>Lower instrument costs</li><li>Less expensive consumables</li><li>Faster analysis workflows</li></ul>Current PFAS testing requires substantial expertise, specialized instrumentation, and rigorous quality control, making widespread implementation challenging.<h4>Dr. Terry's Perspective on Long-Term Solutions</h4>When asked what major PFAS challenge she would most like to solve, Dr. Terry offered a broader perspective.Rather than focusing solely on remediation, she emphasized prevention.Her view is that society should:<ul><li>Better evaluate chemical toxicity before commercialization</li><li>Assess risks before large-scale deployment</li><li>Reduce introduction of harmful compounds into the environment</li><li>Support utilities tasked with contaminant removal</li></ul>She notes that water utilities often bear the responsibility of removing contaminants they did not create, highlighting the need for broader societal and regulatory support.<h4>Final Thoughts</h4>Dr. Terry encourages consumers to:<ul><li>Learn where their drinking water originates</li><li>Read annual water quality reports</li><li>Stay informed about local water quality</li><li>Consider appropriate home filtration where needed</li></ul>At the same time, she emphasizes confidence in municipal water systems and the importance of continued investment in water quality research, monitoring, and treatment technologies.<h4>Conclusion</h4>PFAS remain one of the most complex challenges in environmental chemistry and water treatment. Through advanced analytical methods such as LC-MS/MS, combustion ion chromatography, fluorine mass balance approaches, and large-scale monitoring programs, researchers like Dr. Leigh Terry are helping improve our understanding of these persistent contaminants.The interview highlights that solving the PFAS challenge will require a combination of better analytical tools, improved treatment technologies, stronger regulatory frameworks, and a greater emphasis on prevention before contaminants enter the environment.<blockquote>This text has been automatically transcribed from a video presentation using AI technology. It may contain inaccuracies and is not guaranteed to be 100% correct.</blockquote><blockquote><h4>Concentrating on Chromatography Podcast</h4>Dive into the frontiers of chromatography, mass spectrometry, and sample preparation with host David Oliva. Each episode features candid conversations with leading researchers, industry innovators, and passionate scientists who are shaping the future of analytical chemistry. From decoding PFAS detection challenges to exploring the latest in AI-assisted liquid chromatography, this show uncovers practical workflows, sustainability breakthroughs, and the real-world impact of separation science. Whether you’re a chromatographer, lab professional, or researcher you'll discover inspiring content!You can find Concentrating on Chromatography Podcast in podcast apps:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://open.spotify.com/show/1wZg67rCjoGju4yhqxI3tL">Spotify</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podcasts.apple.com/tz/podcast/concentrating-on-chromatography/id1788429185">Apple podcast</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podscan.fm/podcasts/concentrating-on-chromatography">podscan</a></li></ul>and on <a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/@ChromatographyTalk/videos">YouTube channel</a></blockquote>

PFAS in Water: Why We’re Missing 96% of the Problem

Article

Product

Video

Scientists

Environment

Water

Interview

Science and research

Software

Since 1991 DataApex develops and manufactures chromatography data stations. DataApex is constantly striving to provide users with efficient and up-to-date tools for chromatography data processing.

DataApex

The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences (IOCB Prague) is a leading scientific institution in the Czech Republic, recognized internationally. Its primary mission is basic research in the fields of chemical biology and medicinal chemistry, organic and material oriented chemistry, chemistry of natural compounds, biochemistry and molecular biology, physical chemistry, theoretical chemistry, and analytical chemistry. 

Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences

Organomation, founded in 1959, designs and manufactures high-quality nitrogen evaporators and extraction systems. Known for innovation and durability, their lab instruments are used globally for efficient sample preparation with strong customer support.

Organomation

Metrohm

From applied research to corrosion monitoring to quality control of boiler feed water in the power industry – voltammetry is widely used for highly selective and sensitive analysis of heavy metals. Now, a new generation of mercury-free sensors developed by Metrohm makes this method «green» and hence compliant with increasingly tougher environmental regulations in many countries.
Join Jakub Tymoczko, Application Specialist at Metrohm International Headquarters, in his webinar on December 13, as he explains how to perform «green voltammetry» in the laboratory as well as in the field for fast determination and speciation of heavy metals ranging from arsenic to zinc.
Key learnings of this webinar:
<ul>
<li>The principle behind the new generation of Metrohm&#39;s mercury-free sensors</li>
<li>The inherent benefits of voltammetry for heavy metal analysis (lower costs, easier to use, faster results than by competing methods, e.g., ICP-MS)</li>
<li>Typical application examples from different fields (research, process control, monitoring of drinking water)</li>
<li>Automation possibilities for high throughput analysis of large sample series</li>
</ul>
<blockquote>
Presenter: Jakub Tymoczko, PhD (Application Specialist Voltammetry, Metrohm International Headquarters)
</blockquote>
<blockquote>
Dr. Jakub Tymoczko has worked for the Competence Center Voltammetry at Metrohm International Headquarters in Switzerland since 2015. In this time, he has been in charge of developing Metrohm&#39;s new generation of mercury-free sensors and methods for heavy metal detection. Jakub has a Master in biochemistry and received his PhD in electrochemistry on the engineering of model electrocatalysts for energy conversion and storage from the Ruhr-University in Bochum.
</blockquote>

Metrohm: Voltammetry goes green – mercury-free analysis of heavy metals

Voltammetry goes green – mercury-free analysis of heavy metals

How to perform «green voltammetry» in the laboratory as well as in the field for fast determination and speciation of heavy metals ranging from arsenic to zinc.

Green voltammetry – mercury-free analysis of heavy metals

From applied research to corrosion monitoring to quality control of boiler feed water in the power industry – voltammetry is an established method for highly selective and sensitive analysis of heavy metals. Now, a new generation of mercury-free sensors developed by Metrohm makes this method «green» and hence compatible with increasingly tougher environmental regulations in many countries.
Join Jakub Tymoczko, Application Specialist at Metrohm International Headquarters, in his webinar on November 2 and learn how how you can perform «green voltammetry» in the laboratory as well as in the field for fast determination and speciation of heavy metals ranging from arsenic to zinc.
Key learnings of this webinar:
<ul>
<li>The principle behind the new generation of mercury-free sensors from Metrohm</li>
<li>The inherent benefits of voltammetry for heavy metal analysis such as lower costs, easier to use, faster results than by competing methods, e.g., ICP-MS</li>
<li>Typical application examples from different fields (research, process control, monitoring of drinking water)</li>
<li>Automation possibilities for high throughput analysis of large sample series</li>
</ul>
<blockquote>
Presenter: Jakub Tymoczko (Application Specialist Voltammetry, Metrohm International Headquarters)
</blockquote>
<blockquote>
Dr. Jakub Tymoczko has worked for the Competence Center Voltammetry at Metrohm International Headquarters in Switzerland since 2015. In this time, he has been in charge of developing Metrohm&#39;s new generation of mercury-free sensors and methods for heavy metal detection. Jakub has a Master in biochemistry and received his PhD in electrochemistry on the engineering of model electrocatalysts for energy conversion and storage from the Ruhr-University in Bochum.
</blockquote>

Metrohm: Green voltammetry – a new generation of sensors for mercury-free analysis of heavy metals

Green voltammetry – a new generation of sensors for mercury-free analysis of heavy metals

How you can perform «green voltammetry» in the laboratory as well as in the field for fast determination and speciation of heavy metals.

This webinar is offered several times. Select the date and time that works best for you.
<ul>
<li>Tue, Mar 19, 2024, 10:00 AM - 11:00 AM CET</li>
<li>Tue, Mar 19, 2024, 3:30 PM - 4:30 PM CET</li>
</ul>
Ever wondered about what&#39;s inside your potentiostat and whether it really matters? In this webinar we&#39;ll answer questions you&#39;ve always wanted to ask, explain how a potential is applied or a current measured in a conventional three-electrode setup. Do you know what the compliance voltage or the bandwidth of the instrument is, and why one should care?
With a good understanding of how the instrument is made and operates you’ll be able to make sense of the data it provides, troubleshoot common electrochemical experiments, and boost your confidence in the lab. 
This webinar is accessible to anyone: no background in electronics is required. 
<blockquote>
Presenter: Thomas Touzalin, PhD. (Product Manager at Metrohm Autolab)
</blockquote>
<blockquote>
Helping the electrochemistry researchers achieve their goals by providing the right solution for any research problems as well as offering technical support for the Autolab product range.
</blockquote>
Surprise: We will be giving away the &quot;A guide to flawless electrochemical measurements&quot; lab poster, a step-by-step guide to address common issues you may encounter when using a potentiostat. You can hang it in your lab to ensure the success of every experiment. If you would like to stand a chance to win one through a lucky draw, please indicate below.

Metrolab: Beyond the black box: how a potentiostat works

Beyond the black box: how a potentiostat works

In this webinar we'll explain how a potential is applied or a current measured in a conventional three-electrode setup.

CVS (Cyclic Voltammetric Stripping) is the preferred method for monitoring the concentration of suppressors, brighteners, and levelers used in the production of high-quality printed circuit boards (PCBs) and in advanced packaging of semiconductors. Automating this monitoring can help manufacturers to significantly save time and effort while helping them to keep pace with increasing numbers of samples.
In her webinar, Barbara Zumbrägel, Product Manager Voltammetry at Metrohm International Headquarters, will present the latest technology to take fully automated quality control in PCB manufacturing with CVS to the next level of performance, efficiency, and convenience. Following the webinar, Barbara will be available for a Q&amp;A Session to answer any questions you may have.
Key learnings of this webinar:
<ul>
<li>How automated sample transfer and dosing can make your determination of suppressors, brighteners, and levelers more efficient</li>
<li>How to handle the increasing number of auxiliary solutions with an automated pipetting system</li>
<li>How to optimize your workflow by customizing methods in the viva software to meet the specific requirements of your analysis protocol</li>
</ul>
Who should attend?
<ul>
<li>Lab technicians and lab managers from the PCB, PWB, and semiconductor manufacturing industries</li>
</ul>
<blockquote>
Presenter: Barbara Zumbrägel (Product Manager Voltammetry, Metrohm International Headquarters)
</blockquote>
<blockquote>
Barbara Zumbrägel earned her diploma in chemistry from Technische Universität Clausthal, Germany, and joined Metrohm International Headquarters in 1999 as a product and application specialist for voltammetry. Since 2003, she has also played a significant role in the ongoing development of the Metrohm portfolio of CVS products and applications. In 2006, Barbara was promoted to Product Manager Voltammetry.
</blockquote>

Metrohm: Next level of CVS automation - how to increase the efficiency of your routine analysis

Next level of CVS automation - how to increase the efficiency of your routine analysis

Fully automated quality control in PCB manufacturing with CVS for the next level performance, efficiency, and convenience.

CVS automation - how to increase the efficiency

Over the years, viva has become the preferred software solution for voltammetric trace analysis and Cyclic Voltammetric Stripping (CVS). In an upcoming webinar on June 25, we will present how the latest features of viva improve key applications for both techniques.For plating bath analysis by CVS, there is a faster and more accurate way to determine some brighteners. No standard addition is needed for this kind of determination. Moreover, the electrolyte value, required for the response curve (RC), can now be determined and stored separately. It can therefore be used for subsequent calibrations and determinations, reducing the time per analysis and reagent consumption.Regarding voltammetric trace analysis, lower detection limits can now be achieved by subtracting the background signal (blank). This is particularly usefull when working with solid-state electrodes as these often have an irregular background signal, which interferes with the detection of small analyte peaks.Register for this virtual event today to learn more about these and other new features and benefits of viva 4.0!Key Learning Objectives:<ul><li>New features of viva 4.0</li><li>Advantages of using the RC with increasing signals for brightener determination</li><li>The benefits of determining and storing the electrolyte value separately</li><li>Application examples of background subtraction with solid-state electrodes</li></ul>Who Should Attend:<ul><li>Current users of viva software, QC managers from the plating industry, suppliers of organic additives for the plating industry, environmental testing laboratories using solid-stae electrodes and interested in lower detection limits.</li></ul><blockquote>Presenter: Pascal Feurer (Product Specialist Voltammetry and CVS, Metrohm International Headquarters)Pascal Feurer has received his MSc in chemistry at the Zurich University of Applied Sciences. He has been working at Metrohm International Headquarters for 12 years as a Product Specialist for Voltammetry and CVS, where he gained extensive knowledge in voltammetric trace analysis and plating bath analysis by CVS.</blockquote>

Metrohm: viva 4.0: New key features and benefits for CVS and voltammetric trace analysis

viva 4.0: New key features and benefits for CVS and voltammetric trace analysis

Join the June 25 webinar to explore viva 4.0's new features for CVS and voltammetry—faster analysis, lower detection limits, and smarter electrolyte handling.

viva 4.0: New Features for CVS & Trace Voltammetry

The chemistry of copper plating baths is complex, and each component plays a role in the quality of the final product. The composition evolves as such baths are used and adjustment decisions must be made on reliable, relevant data.In our upcoming webinar, we present a multi‑method analytical approach as the most efficient way to develop and monitor copper deposition baths. By combining titration and cyclic voltammetric stripping (CVS) with complementary techniques such as pH measurement and X‑ray fluorescence (XRF), users gain a complete picture of their plating bath chemistry.Each method targets a specific class of components: While titration offers a robust and efficient way to quantify the main metallic components, salts, and anions, CVS is the industry standard method for measuring the organic additives in the baths. XRF offers additional insight regarding the presence of metallic contaminants and additives.After a close look at the specific strengths of these methods, how they complement each other, and automation options, our presenters will answer any questions you may have on the webinar topic in a Q&amp;A session.<h4>Key learning points of this webinar:</h4><ul><li>Learn the power of method combination: How tiration and CVS can be integrated with other analytical techniques like XRF and pH measurement to provide a more complete understanding of the plating bath chemistry.</li><li>The benefits of automation beyond increased throughput and general convenience: How to eliminate operator relative variance, increase repeatability, and ensure that optimzed analytical approaches can be applied consistently in multiple locations.</li><li>Why our analytical technologies are perfectly suited for the various players in this industry, from bath chemistry development to the production floor.</li></ul><h4>Who should attend this webinar?</h4><ul><li>Production managers that oversee the day-to-day production process</li><li>QC professionals in charge of ensuring product quality</li><li>Researchers involved in the development of new copper plating technologies and advanced bath chemistry</li></ul><blockquote>Presenter: Dr. Julia van Drunen (Head of Competence Center, Voltammetry, Metrohm)Julia van Drunen completed her Ph.D. in electrochemistry at Queen’s University in 2013 and worked for two years as a post-doctoral researcher at the University of Sao Paulo before joining Metrohm Autolab in the Netherlands in 2016 and Metrohm HQ in 2024. She specializes in the topics of surface electrochemistry of nickel and platinum, electrocatalysis, and the corrosion of metals and alloys.Presenter: Dr. Christian Haider (Head of Competence Center Titration, Metrohm International Headquarters)Dr. Christian Haider joined Metrohm International Headquarters in 2002 where he started as an Application Specialist Titration. He has advanced his career at Metrohm to become Head of Competence Center Titration and in this position leads a team of Product Managers, Product Specialists, and Application Chemists for all the different titration techniques, pH and conductivity measurement, titration automation, and software.Presenter: Jeroen Zaalberg (Head of Product Management, Metrohm Applikon)Jeroen Zaalberg joined Metrohm Process Analytics in 2008 and has worked as an application chemist, Product Manager Wet-Chemistry, and is currently in the position of Head of Product Management.Jeroen has a BSc in analytical and physical chemistry and has a passion for product development, innovation and strategy. Over the recent years, Jeroen successfully launched several new products in the Metrohm Process Analytics portfolio.</blockquote>

Metrohm: Copper deposition baths: Advanced analytical solutions for development and monitoring

Copper deposition baths: Advanced analytical solutions for development and monitoring

Learn how titration, CVS, XRF, and pH measurement improve copper plating bath control, data quality, and production consistency.

Copper deposition baths: analytical solutions

EQCM-D can be a powerful tool for furthering electrochemistry research in fields diverse as batteries, corrosion and polymer science. &nbsp;In this webinar, co-organized by 3T-analytik, we’ll break down the theory. Then, through some real-world examples show just how researchers across electrochemistry can use EQCM‑D to bring advanced insight into their research by opening a window into real-time mass, viscoelastic and structural changes during electrochemical processes. This webinar is open to all.

Metrohm: EQCM-D: Advanced Insights into Electrochemistry Applications

EQCM-D: Advanced Insights into Electrochemistry Applications

EQCM-D can be a powerful tool for furthering electrochemistry research in fields diverse as batteries, corrosion and polymer science. 

LCMS webinars focusing on Voltammetry - page 1