Matrix effect evaluation using multi-component post-column infusion in untargeted hydrophilic interaction liquid chromatography-mass spectrometry plasma metabolomics
This study evaluates matrix effects in untargeted HILIC-MS plasma metabolomics using post-column infusion, identifying optimal conditions and improving method reliability for metabolite analysis.
Mo, 7.4.2025
LabRulez
Article | Application
News from LabRulezLCMS Library - Week 14, 2025
This week we bring you application notes by Agilent Technologies, Mestrelab Research, Shimadzu and Waters Corporation, poster by GC Image / MDCW and technical note by Thermo Fisher Scientific!
We, 2.4.2025
LabRulez
Article | Webinars
Webinars LabRulezLCMS Week 14/2025
5 webinars: Oligonucleotide purifications (AEX), Ideal SPE sorbent, Mass spectrometry-driven proteomics, Compact HPLC, PFAS in Drinking Water - Sampling.
Mo, 31.3.2025
LabRulez
Scientific article | Science and research
Hydrophilic interaction liquid chromatography: An efficient tool for assessing thorium interaction with phosphorylated biomimetic peptides
This study uses HILIC-MS to explore how thorium interacts with phosphorylated biomimetic peptides, revealing its affinity and selectivity versus uranium for toxicity modeling.
Mo, 31.3.2025
LabRulez
Article | Application
News from LabRulezLCMS Library - Week 13, 2025
This week we bring you application notes by Agilent Technologies, Knauer, Mestrelab Research, Shimadzu and Waters Corporation and technical note by Thermo Fisher Scientific!
Modeling indirectly detected analyte peaks in ion-pair reversed-phase chromatography
This study models indirect detection using co- and counter-ion probes in chromatography. New isotherm models accurately predicted elution and sensitivity, with errors mostly under 4.72%.
Mo, 24.3.2025
LabRulez
Article | Application
News from LabRulezLCMS Library - Week 12, 2025
This week we bring you application notes by Agilent Technologies, Knauer, Shimadzu and Waters Corporation and technical notes by ALS Europe and Thermo Fisher Scientific!