Matrix effect evaluation using multi-component post-column infusion in untargeted hydrophilic interaction liquid chromatography-mass spectrometry plasma metabolomics
Scientific article | Science and research

Matrix effect evaluation using multi-component post-column infusion in untargeted hydrophilic interaction liquid chromatography-mass spectrometry plasma metabolomics

This study evaluates matrix effects in untargeted HILIC-MS plasma metabolomics using post-column infusion, identifying optimal conditions and improving method reliability for metabolite analysis.
Mo, 7.4.2025
LabRulez
tag
share
more
Matrix effect evaluation using multi-component post-column infusion in untargeted hydrophilic interaction liquid chromatography-mass spectrometry plasma metabolomics
News from LabRulezLCMS Library - Week 14, 2025
Article | Application

News from LabRulezLCMS Library - Week 14, 2025

This week we bring you application notes by Agilent Technologies, Mestrelab Research, Shimadzu and Waters Corporation, poster by GC Image / MDCW and technical note by Thermo Fisher Scientific!
We, 2.4.2025
LabRulez
tag
share
more
News from LabRulezLCMS Library - Week 14, 2025
Webinars LabRulezLCMS Week 14/2025
Article | Webinars

Webinars LabRulezLCMS Week 14/2025

5 webinars: Oligonucleotide purifications (AEX), Ideal SPE sorbent, Mass spectrometry-driven proteomics, Compact HPLC, PFAS in Drinking Water - Sampling.
Mo, 31.3.2025
LabRulez
tag
share
more
Webinars LabRulezLCMS Week 14/2025
Hydrophilic interaction liquid chromatography: An efficient tool for assessing thorium interaction with phosphorylated biomimetic peptides
Scientific article | Science and research

Hydrophilic interaction liquid chromatography: An efficient tool for assessing thorium interaction with phosphorylated biomimetic peptides

This study uses HILIC-MS to explore how thorium interacts with phosphorylated biomimetic peptides, revealing its affinity and selectivity versus uranium for toxicity modeling.
Mo, 31.3.2025
LabRulez
tag
share
more
Hydrophilic interaction liquid chromatography: An efficient tool for assessing thorium interaction with phosphorylated biomimetic peptides
News from LabRulezLCMS Library - Week 13, 2025
Article | Application

News from LabRulezLCMS Library - Week 13, 2025

This week we bring you application notes by Agilent Technologies, Knauer, Mestrelab Research, Shimadzu and Waters Corporation and technical note by Thermo Fisher Scientific!
We, 26.3.2025
LabRulez
tag
share
more
News from LabRulezLCMS Library - Week 13, 2025
Webinars LabRulezLCMS Week 13/2025
Article | Webinars

Webinars LabRulezLCMS Week 13/2025

15 webinars: Metabolites, LCMS & DL, Proteomics, SEISMIC, HRMS & TOX, Purification, Vaccines, SFC, SEC/GPC, Compound Discoverer, Evosep One, IC, UV-Vis-NIR.
Mo, 24.3.2025
LabRulez
tag
share
more
Webinars LabRulezLCMS Week 13/2025
Modeling indirectly detected analyte peaks in ion-pair reversed-phase chromatography
Scientific article | Science and research

Modeling indirectly detected analyte peaks in ion-pair reversed-phase chromatography

This study models indirect detection using co- and counter-ion probes in chromatography. New isotherm models accurately predicted elution and sensitivity, with errors mostly under 4.72%.
Mo, 24.3.2025
LabRulez
tag
share
more
Modeling indirectly detected analyte peaks in ion-pair reversed-phase chromatography
News from LabRulezLCMS Library - Week 12, 2025
Article | Application

News from LabRulezLCMS Library - Week 12, 2025

This week we bring you application notes by Agilent Technologies, Knauer, Shimadzu and Waters Corporation and technical notes by ALS Europe and Thermo Fisher Scientific!
We, 19.3.2025
LabRulez
tag
share
more
News from LabRulezLCMS Library - Week 12, 2025
Webinars LabRulezLCMS Week 12/2025
Article | Webinars

Webinars LabRulezLCMS Week 12/2025

14 webinars: PFAS, Pesticides, LC Troubleshooting, Pharmaceuticals QC, (EU) 2020/2184, SEC, Purifications, DLS, Columns, Biotherapies, Vaccines, Food QC.
Mo, 17.3.2025
LabRulez
tag
share
more
Webinars LabRulezLCMS Week 12/2025
Quantification of Gd species in a tetrameric Gd-based contrast agent using HPLC-ICP-MS
Scientific article | Science and research

Quantification of Gd species in a tetrameric Gd-based contrast agent using HPLC-ICP-MS

This study presents an HPLC-ICP-MS method for precise quantification of Gd complexes in Gadoquatrane, enabling detection of trace by-products to optimize synthesis and drug control strategies.
Mo, 17.3.2025
LabRulez
tag
share
more
Quantification of Gd species in a tetrameric Gd-based contrast agent using HPLC-ICP-MS
Other projects
GCMS
ICPMS
Follow us
FacebookX (Twitter)LinkedInYouTube
More information
WebinarsAbout usContact usTerms of use
LabRulez s.r.o. All rights reserved. Content available under a CC BY-SA 4.0 Attribution-ShareAlike