Mass Spectrometric Characterization of Antibody-RNA Conjugates using the Agilent 6545XT AdvanceBio LC/Q-TOF
Posters | 2020 | Agilent TechnologiesInstrumentation
LC/TOF, LC/HRMS, LC/MS, LC/MS/MS
IndustriesPharma & Biopharma
ManufacturerAgilent Technologies
Key wordsconjugates, rna, mab, antibody, advancebio, condition, under, sirna, native, denaturing, thiomab, intact, delivery, spanned, payloads, sec, swarm, characterization, thiol, deglycosylated, unreacted, reacted, mediated, overcomes, various, conjugate, denatured, gray, reprint, peaks, oligonucleotide, autotune, chromatographic, partially, dissociation, highlighted, deconvoluted, purified, agent, poster, indicating, spectrometric, antibodies, forms, therapeutic, discussion, identifying, industrial, issues, comparable
Similar PDF
Mass Spectrometric Characterization of Antibody-siRNA Conjugates using the Agilent 6545XT AdvanceBio LC/Q‑TOF
2020|Agilent Technologies|Applications
Application Note Pharma & Biopharma Mass Spectrometric Characterization of Antibody-siRNA Conjugates using the Agilent 6545XT AdvanceBio LC/Q‑TOF Author David L. Wong Agilent Technologies, Inc. Abstract Small interfering RNAs (siRNAs) are a promising type of RNA-based therapeutic drugs that demonstrate effectiveness…
Key words
sirna, sirnamab, mabconjugates, conjugatesintact, intactcounts, countsdeglycosylated, deglycosylateddeconvoluted, deconvolutednative, nativeamu, amumass, massadvancebio, advancebiorna, rnaantibody, antibodysirnas, sirnaslinker
Characterization of Antibody‑Drug Conjugates Using 2D-LC and Native MS
2021|Agilent Technologies|Applications
Application Note Biopharma/Pharma Characterization of Antibody‑Drug Conjugates Using 2D-LC and Native MS Authors David L. Wong and Sarah M. Stow Agilent Technologies, Inc. Abstract Antibody drug conjugates (ADCs), which comprise a monoclonal antibody (mAb) conjugated to a small molecule drug…
Key words
dimension, dimensiondar, daradcs, adcsadc, adcsecond, secondnative, nativehic, hicadvancebio, advancebiocounts, countsmab, mabdrug, drugdeconvoluted, deconvolutedfirst, firstconjugated, conjugatedintact
Analysis of Antibody siRNA Conjugate Using BioAccord System
2021|Waters|Applications
Application Note Analysis of Antibody siRNA Conjugate Using BioAccord System Henry Shion, Catalin E. Doneanu, Ed Ha, Ying Qing Yu, Weibin Chen Waters Corporation, Angiex, Inc. Biopharmaceutical services at Waters Immerse Innovation and Research Center (www.waters.com/immerse <http://www.waters.com/immerse> ) aim to…
Key words
sirna, sirnaarc, arcantibody, antibodybioaccord, bioaccordantisense, antisensestrand, strandconjugate, conjugateresidue, residuesense, senseattach, attachconjugates, conjugatesconfirmation, confirmationcysteine, cysteinederivatized, derivatizedtarget
Characterization of Antibody Drug Conjugates (ADC) using 2-Dimension Liquid Chromatography (2D-LC) and Native Mass Spectrometric Technologies
2021|Agilent Technologies|Posters
Poster Reprint ASMS 2021 Poster number ThP003 Characterization of Antibody-Drug Conjugates (ADC) using 2-Dimension Liquid Chromatography (2D-LC) and Native Mass Spectrometric Technologies David L. Wong and Sarah M. Stow Agilent Technologies, Inc., Santa Clara, CA, USA Introduction Antibody drug conjugates…
Key words
drug, drughic, hicadc, adcantibody, antibodyadvancebio, advancebiodar, darmab, mabintact, intactconjugates, conjugatesbrentuximab, brentuximabvedotin, vedotinnative, nativeconjugated, conjugatedspectrometric, spectrometrichydrophobic