
Looking for answers to the most complex scientific challenges is what you do, and the scientific tools you deploy and the information they provide can make all the difference. With industry-leading separations performance, the ACQUITY UPLC I-Class PLUS System provides new possibilities for maximizing the resolution and sensitivity of your methods, enhancing the characterization of your samples, and improving productivity to advance the science of your laboratory.
With the ACQUITY UPLC I-Class PLUS System, your lab can achieve highly efficient, rapid separations from ultra-low dispersion and delay volume. The system enables your lab to get narrow, ultra-efficient peaks, enhancing the sensitivity of any mass spectrometer and simplifying the characterization of the most complex sample.
Enhance the characterization of your samples, while improving productivity to advance the science of your laboratory.
Waters ACQUITY UPLC I-Class PLUS System: ACQUITY UPLC I-Class PLUS System FTN-H PDA angled.
Get improved resolution through reduced system dispersion with the ACQUITY UPLC I-Class PLUS System, providing separations that can amplify your research.
Shorten analysis times, reduce solvent usage, and speed access to the data you need for critical decisions. Designed to fit into your existing LC workflow, the ACQUITY UPLC I-Class PLUS System provides a clear view into what lies within the sample.
Waters ACQUITY UPLC I-Class PLUS System: In this example, the impurity analysis of tetracaine was run under the same conditions on the ACQUITY UPLC I-Class PLUS System (system band spread of 4 µL) and a UHPLC system (system band spread of 20 µL). Significantly better resolution was achieved on the ACQUITY UPLC I-Class PLUS System.
The ACQUITY UPLC I-Class PLUS System is designed specifically for the rapid pace of laboratories on the cutting edge of research where LC-MS plays a critical role.
With the ACQUITY UPLC I-Class PLUS System, your lab will:
Waters ACQUITY UPLC I-Class PLUS System: A high sensitivity UPLC-MS/MS bioanalytical methodology for the quantification of midazolam and imipramine in rat plasma using the Xevo TQ Absolute Tandem Quadrupole Mass Spectrometer in combination with an ACQUITY UPLC I-Class PLUS System.
When paired with CORTECS 1.6 µm solid-core columns, the ACQUITY UPLC I-Class PLUS System enables scientists to achieve new levels of resolution, sensitivity, and chromatographic performance. With CORTECS Columns and the ACQUITY UPLC I-Class PLUS System, you can increase resolution for even your toughest samples and get the flexibility and power you need to rapidly separate a wide array of compounds.
Waters ACQUITY UPLC I-Class PLUS System: By pairing the ultra-low dispersion ACQUITY UPLC I-Class PLUS System with high-efficiency CORTECS Columns, you’ll achieve new levels of UPLC performance. These 1.6 µm columns deliver exceptional levels of efficiency, performance, and throughput, resulting in narrower peaks and higher peak capacity.

