
The Thermo Scientific VeriSpray PaperSpray Ion Source is a mass spectrometry ionization source designed to enable direct sample analysis without chromatographic separation. Based on paper spray ionization technology, it significantly simplifies analytical workflows while delivering rapid and reliable MS results from complex sample matrices.
Samples are applied to a paper substrate, wetted with solvent, and ionized by applying a high voltage. The resulting ions are introduced directly into the mass spectrometer via electrospray ionization, eliminating the need for time-consuming sample preparation or chromatography. This approach enables data acquisition within minutes and supports high-throughput analysis.
Thermo Scientific VeriSpray PaperSpray Ion Source for Mass Spectrometry
The VeriSpray ion source is engineered for unattended, high-capacity operation, allowing the analysis of hundreds of samples with minimal manual intervention. By removing chromatographic steps, solvent consumption is reduced, instrument maintenance demands are lowered, and overall cost per test is significantly decreased.
Fully integrated with Thermo Scientific TSQ Series mass spectrometers, the VeriSpray ion source is controlled through established software platforms, offering streamlined method setup, automated operation, and efficient data processing. This makes advanced mass spectrometric analysis accessible even in laboratories without extensive chromatography expertise.
The VeriSpray PaperSpray Ion Source is particularly well suited for rapid quantitative analysis and screening applications in pharmaceutical, clinical, and research environments where speed, simplicity, and cost efficiency are essential.
Thermo Scientific VeriSpray PaperSpray Ion Source for Mass Spectrometry: For Research Use Only. Not for use in diagnostic procedures.
The VeriSpray™ PaperSpray Ion Source improves turnaround time and reduces cost per test by eliminating chromatographic separation and minimizing sample preparation. Direct ionization enables one-step analysis of unprocessed samples, with MS results typically available in less than two minutes.
Designed for high-throughput operation, the system supports unattended analysis of large sample batches and can be expanded with an optional automated plate loader for increased productivity. Proprietary VeriSpray PaperSpray sample plates are available for single-sample and high-throughput workflows, including barcoded formats to support automated sample tracking and integration with commercial robotic systems.
The VeriSpray ion source is fully integrated into Thermo Scientific instrument control and application software, providing complete source control, predefined method templates, and streamlined data acquisition. Optional data analysis software further supports quantitative and screening applications in areas such as food safety, environmental analysis, clinical research, and forensic toxicology.
Thermo Scientific VeriSpray PaperSpray Ion Source for Mass Spectrometry
The VeriSpray™ PaperSpray Ion Source is compatible with Thermo Scientific TSQ triple quadrupole mass spectrometers, including:
Thermo Scientific VeriSpray PaperSpray Ion Source for Mass Spectrometry

