Visit the LabRulez booth at <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/events/871">analytica 2026</a> in Munich, 24. - 27. March 2026! You can find us in Hall A1, Booth A1.506. At the booth, you will be able to explore live demonstrations of how the LabRulez portals work and see selected analytical instruments from our pre-owned marketplace section.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Lab_Rulez_at_Analytica_2026_Floor_plan_55e1057e03.jpg" alt="LabRulez at Analytica 2026: Hall A1 Floor Plan and Booth Location" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Lab_Rulez_at_Analytica_2026_Floor_plan_55e1057e03.jpg 245w," sizes="100vw" width="1516" height="881"><h3>Would you like to learn how the LabRulez portals work?</h3>➡︎ <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/">LabRulezLCMS</a> ➡︎ <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/">LabRulezGCMS</a> ➡︎ <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/">LabRulezICPMS</a><ul><li>A unique online solution for your marketing</li><li>A targeted audience from the analytical chemistry community</li><li>Modern technologies and a unique concept</li><li>Design optimized for most smart devices – PC, mobile, and tablet</li><li>Advanced statistical tools fully available to users</li></ul><h3>Services Offered</h3><h4>News + Company Updates</h4><ul><li>Publish news related to your instrumentation, applications, services, events, job openings, and more</li><li>News is shared both on our portals and across our social media channels</li></ul><h4>Library – All Documents in One Place</h4><ul><li>Applications, posters, presentations, technical articles, brochures, specifications</li><li>Fast and advanced search capabilities</li><li>Over 32,000 documents currently available in our database</li></ul><h4>Webinars</h4><ul><li>Upcoming and on-demand webinars from the field of analytical chemistry</li><li>More than 5,500 webinars covering chromatography, mass spectrometry, and spectroscopy</li></ul><h4>Careers</h4><ul><li>Targeted job listings in analytical chemistry</li><li>Clear filtering by specialization or location</li><li>Increased visibility for job postings</li></ul><h4>Companies</h4><ul><li>Company profile with key information and contacts</li><li>Integration of all your activities on our portal: News, Library documents, Webinars, Upcoming Events, Careers, and mentions by partners or customers</li><li>Connection to your Products listed on LabRulez portals</li></ul><h4>Products and Services</h4><ul><li>Comprehensive overview of instrumental techniques and services</li><li>Targeting the analytical chemistry community and customers in the growing online environment</li></ul><h4>Marketplace</h4><ul><li>Buying and selling pre-owned analytical equipment</li><li>We purchase analytical instrumentation of all brands and ages</li><li>Sell your equipment through LabRulez</li><li>Request and purchase complete systems, modules, or spare parts with warranty and service</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Lab_Rulez_at_analytica_2026_bazar_7edf4a0872.jpg" alt="LabRulez at analytica 2026" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Lab_Rulez_at_analytica_2026_bazar_7edf4a0872.jpg 88w," sizes="100vw" width="1600" height="2844"><h3>What Will Be on Display at Our Booth?</h3>Come and explore selected spare parts and modules from our marketplace section. These include both new, tested, and pre-owned items.<h4><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/bazaar">LabRulezLCMS Marketplace</a></h4>Spare parts for LC/MS:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/bazaar?category=378">Vacuum turbo pumps for LC/MS</a></li></ul>Spare parts for HPLC:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/bazaar?category=397">Degassers for HPLC/UHPLC</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/bazaar?category=368&amp;search=valve">Automatic valves for HPLC</a></li><li>HPLC components for Agilent 1100, 1200, and 1260 Infinity II series</li></ul>Consumables:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/bazaar?category=377">HPLC lamps</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/bazaar?category=48">HPLC columns</a></li></ul><h4><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar">LabRulezGCMS Marketplace</a></h4>Spare parts for GC/MS:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar?category=367&amp;search=turbo">Turbo pumps for GC/MS</a></li></ul>Spare parts for GC:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar?category=366&amp;search=EPC">EPC modules</a></li></ul>Sample injection<ul><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar/432">Autosampler 7693A for GC</a></li></ul>Consumables:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar?category=7">GC columns </a>and selected accessories</li></ul>

LabRulez at analytica 2026

🎤Alex BrodyIn this episode of Concentrating on Chromatography, we sit down with Alex Brody, an organic chemist at Aqua America, to discuss the rigorous analytical methods required for regulated drinking water testing.Alex walks us through the multi-step PFAS detection process using EPA Method 537.1, including extraction, nitrogen blowdown concentration, and LC-MS analysis. He explains why sample preparation and quality control are critical for achieving trace-level detection—and why these methods can't be rushed or simplified, even with new technologies available.We also explore taste and odor investigations, disinfection byproducts, and volatile organic compounds, plus the surprising reality of why regulated labs move slowly when adopting new instrumentation. You'll learn about the quality control checkpoints, peer review processes, and the misconceptions surrounding analytical turnaround times in compliance labs.<h5>Topics Covered:</h5><ul><li>Role of organic chemistry in regulated drinking water labs</li><li>EPA compliance requirements and regulatory bodies (EPA, PA-DEP)</li><li>PFAS detection using Method 537.1 and LC-MS</li><li>The critical importance of nitrogen blowdown sample concentration</li><li>Taste and odor analysis: MIB, Geosmin, and unknown compound identification</li><li>Why regulated methods evolve slowly (validation timelines, approval processes)</li><li>Quality control procedures: calibration checks, matrix spikes, surrogate standards, internal standards</li><li>Automated sample preparation and lab efficiency</li><li>Future PFAS regulations and Method 533 expansion</li></ul><h5>Ideal For:</h5><ul><li>Analytical chemists and environmental lab professionals</li><li>Water utilities and compliance officers</li><li>Chromatography practitioners interested in regulated workflows</li><li>Anyone curious about how drinking water safety is ensured</li></ul><h2>Video Transcription</h2><h3>Ensuring Safe Drinking Water Through Advanced Analytical Chemistry</h3><h4>Insights from a Regulated Water Testing Laboratory</h4>Analytical laboratories responsible for regulated drinking water testing operate under strict compliance frameworks to ensure the delivery of safe and reliable water supplies. In this interview, Alex, an organic chemist at Aqua America, outlines the scope of analytical work conducted in a modern water quality laboratory. The team primarily focuses on the determination of taste- and odor-causing compounds, disinfection byproducts, volatile organic compounds (VOCs), and per- and polyfluoroalkyl substances (PFAS). These analyses rely heavily on GC-MS and LC-MS instrumentation, supported by rigorous maintenance programs to ensure continuous operational performance and data reliability.<h4>Regulatory Compliance and Quality Control in Drinking Water Analysis</h4>Operating as a regulated drinking water laboratory requires adherence to stringent requirements established by agencies such as the U.S. Environmental Protection Agency (EPA) and state-level regulatory bodies. Compliance is driven by extensive quality control protocols integrated into every analytical batch. Typical workflows include calibration verification, matrix spike recovery assessments, internal standard monitoring, and surrogate performance checks. Notably, analytical batches are often limited in sample number to accommodate a substantial proportion of quality control samples, reflecting the critical importance of data defensibility in regulatory reporting.One common misconception is the perceived speed at which results can be delivered. In reality, comprehensive sample preparation, including extraction procedures and validation steps, can extend turnaround times to a full working day or longer. Additionally, validated regulatory workflows impose limitations on the rapid adoption of new analytical technologies, as method modifications must undergo formal evaluation and approval before implementation.<h4>Analytical Strategies for Taste and Odor Investigations</h4>Taste and odor events represent a significant operational challenge for water utilities. Standard targeted methods are routinely applied for compounds such as 2-methylisoborneol (MIB) and geosmin, which are commonly associated with earthy or musty sensory characteristics. When targeted analysis does not reveal the source, laboratories employ broad-scan GC-MS screening combined with spectral library interpretation to identify potential causative compounds. In some cases, sensory evaluation panels complement instrumental analysis, providing preliminary insight into potential treatment-related or environmental influences affecting water quality.<h4>PFAS Monitoring: Methodological Complexity and Trace-Level Sensitivity</h4>PFAS determination represents a rapidly evolving priority in drinking water monitoring. The laboratory currently applies EPA Method 537.1, with efforts underway to expand capabilities through certification for Method 533, thereby broadening analyte coverage. Analytical workflows typically involve solid-phase extraction followed by solvent evaporation using nitrogen-assisted blow-down techniques to achieve the trace-level sensitivity required for regulatory compliance. This concentration step is essential because PFAS compounds remain non-volatile under controlled evaporation conditions, enabling enhanced detection performance upon reconstitution and LC-MS analysis.<h4>Future Directions in Drinking Water Analytics</h4>Looking ahead, the primary technological driver in regulated water analysis is the demand for increasingly lower detection limits and expanded compound coverage. While regulatory frameworks can slow methodological innovation, laboratories continue to pursue efficiency improvements, such as automated sample preparation systems and optimized analytical workflows. These advances support the growing need to process high sample volumes while maintaining the stringent data quality standards required for public health protection.Ultimately, the work performed in regulated drinking water laboratories represents a critical intersection of analytical chemistry, environmental monitoring, and public safety. Continuous methodological refinement, coupled with advances in mass spectrometry and sample preparation technologies, will play a central role in addressing emerging contaminants and ensuring long-term water quality assurance.<blockquote>This text has been automatically transcribed from a video presentation using AI technology. It may contain inaccuracies and is not guaranteed to be 100% correct.</blockquote><blockquote><h4>Concentrating on Chromatography Podcast</h4>Dive into the frontiers of chromatography, mass spectrometry, and sample preparation with host David Oliva. Each episode features candid conversations with leading researchers, industry innovators, and passionate scientists who are shaping the future of analytical chemistry. From decoding PFAS detection challenges to exploring the latest in AI-assisted liquid chromatography, this show uncovers practical workflows, sustainability breakthroughs, and the real-world impact of separation science. Whether you’re a chromatographer, lab professional, or researcher you'll discover inspiring content!You can find Concentrating on Chromatography Podcast in podcast apps:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://open.spotify.com/show/1wZg67rCjoGju4yhqxI3tL">Spotify</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podcasts.apple.com/tz/podcast/concentrating-on-chromatography/id1788429185">Apple podcast</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podscan.fm/podcasts/concentrating-on-chromatography">podscan</a></li></ul>and on <a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/@ChromatographyTalk/videos">YouTube channel</a></blockquote>

Regulated Drinking Water Testing: PFAS Detection, Sample Prep & Real Lab Insights

Anna Vanluchene&nbsp;from UCT Prague’s&nbsp;Department of Chemical Engineering has received a&nbsp;prestigious start-up grant from the Dagmar Procházková Fund. However, she did not receive funding right away. In this interview, she describes how she developed ten versions of her&nbsp;Illuminating Flow&nbsp;project idea (combining photocatalysis with flow reactors for pharmaceutical synthesis). She explains why she considers perseverance to be crucial when applying for grants, how international experience has influenced her approach to team management, and how her research can reduce the chemical industry’s&nbsp;dependence on fossil fuels and imports from China.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/VSCHT_Praha_Na_startovaci_grant_jsem_cekala_dva_roky_a_napsala_deset_verzi_projektu_2_5b7d63b8e9.jpg" alt="VŠCHT Prague/Tomáš Balický: I waited two years for a start-up grant and wrote ten versions of my project idea" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_VSCHT_Praha_Na_startovaci_grant_jsem_cekala_dva_roky_a_napsala_deset_verzi_projektu_2_5b7d63b8e9.jpg 127w," sizes="100vw" width="1128" height="1387"><h5>What did the Dagmar Procházková Fund grant mean to you?</h5>I&nbsp;consider it to be a&nbsp;great success. It is the first injection of funding that will allow me to ensure full independence for my research endeavour, to start my own research group, and to fund students so I&nbsp;can get started properly.<h5>What have been your previous experiences with grants?</h5>During my doctorate, a cotutelle (international doctorate under dual supervision), I&nbsp;was funded by a&nbsp;grant from the French government. Then I&nbsp;worked at the Academy of Sciences of the Czech Republic (CAS) and received a&nbsp;Marie Skłodowska-Curie Action (MSCA) Postdoctoral Fellowship to go abroad. The idea for my now-funded project was developed about two years ago and, since then, I&nbsp;have gradually developed and adapted the idea for various grant calls. I&nbsp;submitted about ten different versions of the proposal. I&nbsp;did not receive a&nbsp;grant from the Dagmar Procházková Fund last year, but this year, my application was successful.<h5>This probably requires a&nbsp;great deal of patience and perseverance.</h5>Certainly, because the success rates for most grants have been declining for some time. But as a&nbsp;motivational example, I&nbsp;will tell the story of Timothy Noel, a&nbsp;Belgian professor of chemistry living in the Netherlands. He applied for the prestigious European Research Council (ERC) grant, which is among the most sought-after in Europe, seven times. But no failure deterred him and eventually he succeeded and opened the door to potentially massive grant funding. He was already one of the world’s&nbsp;top scientists in the field at that time and openly described his journey on his blog <a target="_blank" rel="noopener noreferrer" href="https://www.noelresearchgroup.com/2022/03/17/my-personal-story-to-obtain-an-erc-grant-7-submissions-4-interviews-and-6-heartbreaks/">blog</a>.<h5>What advice does this convey to other grant applicants and early career researchers?</h5>Start early, read a&nbsp;lot, don’t&nbsp;give up, and—most importantly—apply repeatedly. Learn from rejections and overcome possible frustration from failures. Read blogs and books by successful people, where you will find not only the glorious results of their work, but also the hardships they faced over their entire journeys. Of course, building your team and laboratory is impossible without finances. I&nbsp;myself still hope that I&nbsp;will be able to receive even bigger grants in the future.<h5>How has your international experience influenced your scientific approach?</h5>A&nbsp;lot and on several levels. Different laboratories teach you how to do&nbsp;things differently. You gain varied experience about how different institutions function. You see other people’s&nbsp;positive motivations, their ability to be ambitious without negativity, their involvement in institutional matters, their openness to cooperation with companies (e.g., tech transfers, spin-offs). The most important thing is to broaden your horizons. I&nbsp;see going abroad as a&nbsp;necessity. What I&nbsp;have taken away the most is drive, great support, and the idea that scientific output is not just about metrics, but also about dedication to one’s&nbsp;topic.<h5>What is your Illuminating Flow: Transport Phenomena in Photocatalysis about, in layperson’s&nbsp;terms, and how is it unique?</h5>Most of today’s&nbsp;chemical industry is still based on thermal processes and fossil fuels. Photochemistry enables electrification, where the energy source is photons delivered by LEDs, which can generate electricity from renewable sources. Current research focuses mainly on chemical reactions and their mechanisms, but as a&nbsp;chemical engineer, I&nbsp;focus on designing processes and reactors suitable for industrial use. In batch reactors, light fades rapidly with distance from a&nbsp;source, so much of a&nbsp;reaction mixture is not illuminated. Flow reactors solve this problem, but they bring new challenges such as working with solid catalysts and subsequently scaling up production and achieving higher production rates of the desired chemicals at a&nbsp;given scale.One can imagine a&nbsp;transparent tube with a&nbsp;catalyst on the walls, upon which light shines and through which reactants flow. This project has a&nbsp;unique emphasis on engineering solutions and overall process efficiency.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/VSCHT_Praha_Na_startovaci_grant_jsem_cekala_dva_roky_a_napsala_deset_verzi_projektu_3_b978abf25c.jpg" alt="VŠCHT Prague/Tomáš Balický: I waited two years for a start-up grant and wrote ten versions of my project idea" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_VSCHT_Praha_Na_startovaci_grant_jsem_cekala_dva_roky_a_napsala_deset_verzi_projektu_3_b978abf25c.jpg 241w," sizes="100vw" width="1228" height="799"><h5>So, were you inspired by a&nbsp;gap in the market to connect photocatalysis with transport phenomena?</h5>Exactly. I&nbsp;combine my areas of expertise: microfluidics, photocatalytic degradation of organic substances (CAS), and synthesis (MSCA Postdoctoral Fellowship). The idea itself is not new, and pharmaceutical companies are very interested in “greener” photochemistry, but in practice, there is often a&nbsp;lack of appropriate engineering solutions and apparatus for industrial use.<h5>What are the practical applications of your work and what substances are you focusing on?</h5>Mainly on pharmaceuticals and on the synthesis of so-called fine chemicals, which are often the building blocks for the production of pharmaceuticals. There is also a&nbsp;geopolitical dimension to this, i.e. less dependence on imports from China and sustainable synthesis in Europe where it makes economic sense.<h5>And what chemicals are you specifically talking about?</h5>For example, building blocks for advanced synthesis, compounds prepared by trifluoromethylation reactions, or products of oxidation reactions with singlet oxygen. At the same time, we focus on reactions that are, in the classical design process, less safe or technologically demanding, where new approaches, such as photochemistry in flow reactors, could be safer and have better process control. Of course, this is not a&nbsp;universal solution for all types of reactions.<h5>The goal of this project?</h5>I&nbsp;plan to start a&nbsp;fully functional laboratory and research team, create high-quality experimental data on selected molecules and based on them, try to build cooperation with industrial partners. Without data, it is impossible to come to companies with just an idea. Within three years, I&nbsp;would like to have results that can be realistically presented and further developed.<h5>What are the main challenges in transport phenomena during photocatalysis?</h5>The methodology for repeatability of experiments in photochemistry is relatively demanding and there are unforeseen obstacles in building apparatus. Also, the scale-up from microliters to a&nbsp;larger scale.<h5>What methodology will you use, and how big are the microreactors and their flow rates?</h5>I&nbsp;have two different directions in methodological design. The first direction involves microreactors the size of a&nbsp;laboratory slide. You make a&nbsp;structure using a&nbsp;laser, and then you have to cast it and make a&nbsp;microreactor. This allows you to quickly adjust the geometry of the reactor. This method is, of course, not applicable in the commercial setting, but it is ideal for studying transport phenomena and precise measurements.The second direction involves reactors that are flow cells. These are already larger, approximately 15 x 15 centimetres, and their flow rates are in the order of millilitres per hour. This is the initial scale that we will further increase during the project.<h5>There is a&nbsp;big difference between a&nbsp;flow rate of microlitres per hour and industrial needs. Will it not work differently in reality?</h5>Our research will focus on studying the phenomena themselves for now, and scaling will be addressed later. In addition, we will combine the experimental data obtained with computer simulations that will help design suitable conditions for a&nbsp;larger scale. For some high-value fine chemicals, these scales, combined with continuous operation or parallelization of reactors, may already be practically usable.<h5>What catalysts will you use and how will you attach them to the reactor walls?</h5>I&nbsp;am focusing on heterogeneous photocatalysis, and we will mainly use graphitic carbon nitride and its more advanced modifications. These are semiconductor materials that can be synthesized relatively easily and are suitable for immobilization on glass reactor walls. A&nbsp;key part of this project is the creation of a&nbsp;stable catalytic layer for long-term flow-through operations. To increase the contact of reactants with the catalyst, we will also consider multiphase modes, for example, gas bubbling, in order to disrupt the otherwise laminar flow.<h5>Why did you choose this field and the Department of Chemical Engineering?</h5>During my postdoc in Belgium, the department had an opening for an Assistant Professor position that caught my attention and I&nbsp;applied for it. I&nbsp;did my undergraduate, graduate, and initial doctoral studies here, and I&nbsp;love the department. I&nbsp;have a&nbsp;Bachelor’s&nbsp;degree in Chemistry.<h5>Are you collaborating with anyone?</h5>We collaborate with BUT Brno focusing on creating layers and immobilizing catalysts on glass, as well as with the Institute of Chemical Process Fundamentals of the Academy of Sciences of the Czech Republic. And as for organic synthesis, we are connected with Ghent University via postdoc internships. At the same time, my colleague Viola Tokárová and I&nbsp;received a&nbsp;Czech Science Foundation grant in cooperation with BUT Brno and Masaryk University, with our part of the project focusing on the use of flow reactors for photochemical reactions and testing the antibacterial properties of photocatalytic materials. And I&nbsp;am writing other grant proposals in which I&nbsp;am trying to build new collaborations.<h5>What does the creation of an independent research group at UCT Prague look like?</h5>I&nbsp;started by renovating the premises that were assigned to me and gradually building my team. It is important for research work to have Ph.D. students; I&nbsp;have already hired one and we will recruit more. In addition to building the group, I&nbsp;will engage in securing further funding for the group, so I&nbsp;will be writing more grant proposals. It is important to think far enough in advance when it comes to prospective funding for a&nbsp;research group.<h5>What type of students are you looking for?</h5>The laboratory and team I&nbsp;are building will be very multidisciplinary, just like the area I&nbsp;am working on. That is why I&nbsp;am looking for students who are attracted to true multidisciplinary research, those who, for example, have knowledge of engineering, but who don’t&nbsp;mind a&nbsp;little bit of pure chemistry. One student in their own right does not have to (and cannot) know every subject, so I&nbsp;will ideally have a&nbsp;team consisting of different people with different research backgrounds. Motivated, DIY-type students who would rather enthusiastically build or invent something themselves than conduct repetitive measurements. Organic or analytical chemists will also find their place here. If this topic is interesting to students in any way, they can definitely contact me. I&nbsp;am also open to interdepartmental cooperation with other UCT Prague Faculties.<h5>How would you describe your path to photocatalysis/chemical engineering?</h5>Studying Chemistry as an undergrad gave me a&nbsp;broad perspective, but I&nbsp;was gradually narrowing my focus and eventually chose engineering. Chemical engineering intrigued me with its logic and was the easiest for me to grasp at the time. But I&nbsp;have always enjoyed working on projects more than the studies themselves. Even during my Bachelor studies, I&nbsp;really enjoyed and was interested in the Professor Štěpánek Group’s&nbsp;projects, where I&nbsp;was doing something completely different than I&nbsp;do&nbsp;now. I&nbsp;only got into photochemistry during my time at CAS and then, during my postdoctoral fellowship, I&nbsp;devoted myself to electrochemistry. My current focus is, thus, a&nbsp;natural interlinking of all these areas. Consequentially, I&nbsp;developed an awareness of the necessity to become independent and return to the department with my own, different research agenda, which, in my opinion, is an important and correct basis for establishing my own research group.<h5>What is the biggest challenge of this project for you?</h5>The transition from being a&nbsp;postdoc to a&nbsp;leadership position is a&nbsp;big change for me and I&nbsp;think it is not talked about enough. It means a&nbsp;shift from my own experimental work to leading a&nbsp;team, planning and delegating tasks, and motivating students. From a&nbsp;practical point of view, one of the main challenges is the transfer of reactions from the microscale to functional systems, the construction of reactors, the immobilization of catalysts, and generally confirming that this direction makes sense in the long term and that it has future potential.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/VSCHT_Praha_Na_startovaci_grant_jsem_cekala_dva_roky_a_napsala_deset_verzi_projektu_1_66ac267e06.jpg" alt="VŠCHT Prague/Tomáš Balický: I waited two years for a start-up grant and wrote ten versions of my project idea" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_VSCHT_Praha_Na_startovaci_grant_jsem_cekala_dva_roky_a_napsala_deset_verzi_projektu_1_66ac267e06.jpg 155w," sizes="100vw" width="830" height="839">

I waited two years for a start-up grant and wrote ten versions of my project idea

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The University of Chemistry and Technology, Prague is a natural centre of first-rate study and research in the area of chemistry in Czechia and is one of the country's largest educational and research institutions focused on technical chemistry, chemical and biochemical technologies, material and chemical engineering, food chemistry, and environmental studies.

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Organomation, founded in 1959, designs and manufactures high-quality nitrogen evaporators and extraction systems. Known for innovation and durability, their lab instruments are used globally for efficient sample preparation with strong customer support.

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Watrex Streamline RI1 Refractive index HPLC detector

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Watrex Streamline VD1 Viscosimetric HPLC detector

 Watrex Streamline™ VD1 viscosimetric detector is designed for detailed characterization of polymer compounds in both aqueous and organic solvents.

Streamline™ VD1 viscosimetric detector measures absolute intrinsic viscosity and is ideal as a detector for online monitoring in any GPC system. VD1 enables measurement of absolute molecular size using Wheatstone bridge operating principle.<h3>FEATURES</h3><ul><li>High sensitivity and stability</li><li>Low-noise</li><li>Open protocol digital data format</li><li>Direct dual analog output</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Watrex_Watrex_Streamline_VD_1_Viscosimetric_detector_Universal_calibration_from_VD_1_data_1_149c741933.jpg" alt="Watrex: Watrex Streamline VD1 Viscosimetric detector - Universal calibration from VD1 data 1"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Watrex_Watrex_Streamline_VD_1_Viscosimetric_detector_Universal_calibration_from_VD_1_data_2_a616c498e8.jpg" alt="Watrex: Watrex Streamline VD1 Viscosimetric detector - Universal calibration from VD1 data 2"><h3>TECHNICAL SPECIFICATION</h3><ul><li>Wavelength Range: 190 – 720 nm</li><li>Baseline Noise: ± 1 x 10-5 AU (@240 nm, 2 sec. risetime)</li><li>Baseline Drift: &lt; 3 x 10-4 AU/h</li><li>Wavelength Accuracy: ± 0.5 nm</li><li>Wavelenghth Reproducibility: ± 0.1 nm</li><li>Mean Pixel Pitch: 2.2 nm</li><li>Resolution (λ FWHM): 7 nm</li><li>Linearity: &gt; 2.5 AU</li><li>Wavelength Program: Programmable, 10 steps</li><li>Analog Output (optional): 1x 1 V</li><li>Options: Dual channel configuration, thermostated flow cell</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Watrex_Watrex_Streamline_VD_1_Viscosimetric_detector_Technical_specification_76756715f6.jpg" alt="Watrex: Watrex Streamline VD1 Viscosimetric detector - Technical specification"><h3>Ordering information:</h3><h5>PN/Component:</h5><ul><li>SVD101-001 Watrex Streamline™ VD1 viscosimetric detector (Price 19 741 € ex VAT)</li></ul>You can also visit this product on the <a target="_blank" rel="noopener noreferrer" href="https://watrex.com/obchod/chromatography/detectors/other-hplc-detectors/streamline-vd1-detector/?utm_source=labrulez&amp;utm_medium=propagace&amp;utm_campaign=labrulez_produkty">Watrex website</a>.

SIELC Alltesta Mini UV-Vis Detector

The Alltesta™ UV-Vis Multi-wavelength Mini Detector is a compact and versatile device that can continuously monitor the optical properties of solutions flowing through it.

The Alltesta™ UV-Vis Multi-wavelength Mini Detector is a compact and versatile device that can continuously monitor the optical properties of solutions flowing through it. The Mini Detector is ideal for use in HPLC, Flow Injection Analysis (FIA), and preparative and flash chromatography.
The device comes standard with four different wavelength channels, including 470 nm (Blue), 520 nm (Green), 630 nm (Red), and a choice between 255 nm or 275 nm for the UV channel. The Mini Detector features a simple setup process with a USB interface that allows it to communicate with the <a href="https://lcms.labrulez.com/products/1242">Alltesta™ Gradient Automated Analyzer</a> or <a href="https://lcms.labrulez.com/products/1243">Alltesta™ Cromite Analyzer</a> or integrate with other instrumentation.
Powered solely by its USB port, this mini detector is capable of monitoring multiple analytes simultaneously. It has a low optical cell volume of &lt; 3 µL, which results in minimal dispersion even at low flow rates, and can collect data at rates of up to 20 sps for all four channels, making it suitable for demanding applications. The Mini Detector boasts low noise and linearity over more than 4 orders of magnitude.
In addition to its compact size and versatility, the Mini Detector also has zero warm-up time and exceptional durability. The detector cell volume is available in two sizes: 3 μL and 10 μL.
<h4>Specifications</h4>
<ul>
<li>Dimensions (WHL): 63 x 46 x 116 mm / 2.48 x 1.81 x 4.57 in</li>
<li>Weight: 0.25 kg / 0.55 lb</li>
<li>Sample Cell Volume: &lt; 3µL</li>
<li>Cell Optical Path: 7.0mm</li>
<li>Liquid Ports: 10-32 UNF</li>
<li>Wavelength Range: 250nm &amp; up</li>
<li>Simultaneous Wavelengths: Up to 4</li>
<li>Data Rate: 20 sps</li>
<li>Noise Level: 0.03 mAU</li>
<li>Power: USB Type B</li>
</ul>
<h4>Software</h4>
The Multi-wavelength Detector can be controlled:
<ul>
<li>directly via serial commands (Alltesta™ protocol available upon request, please contact us at support@sielc.com),</li>
<li>directly via our demo software, allowing to learn the whole functionality of the unit (<a href="https://sielc.com/wp-content/uploads/2022/12/Alltesta_Detector_Control_Windows_10.zip">Windows 10, 32/64bit</a>, 5Mb, <a href="https://sielc.com/wp-content/uploads/2022/12/Alltesta_Detector_Control_Windows_7.zip">Windows 7, 32/64bit</a>, 127Mb)</li>
<li>remotely through our cloud software (as a part of <a href="https://lcms.labrulez.com/products/1242">Alltesta™ Gradient Automated Analyzer</a> and <a href="https://lcms.labrulez.com/products/1243">Alltesta™ Cromite Analyzer</a>).</li>
</ul>
Serial Communication Drivers are available <a href="https://ftdichip.com/drivers/vcp-drivers/">here</a>.

Waters/Wyatt microViscoStar viscometer

The Waters microViscoStar incorporates multiple novel technologies to provide the highest sensitivity, stability and solvent compatibility of any available viscometer for UHPLC. 

<h4>Highly Sensitive</h4>A highly sensitive, on-line differential viscometer used with SEC-MALS-IV to determine the size and conformation of polymers, proteins and peptides separated by UHPLC.<h4>Multiple Novel Technologies</h4>The microViscoStar™ incorporates multiple novel technologies to provide the highest sensitivity, stability and solvent compatibility of any available viscometer for UHPLC. Its ease-of-use and serviceability make it the perfect companion for Wyatt's microDAWN™ light scattering and microOptilab™ refractive index detectors for UHPLC.<h4>Another path to polymer and protein characterization: SEC-MALS-IV</h4>When coupled with size-exclusion chromatography and a concentration detector such as the Optilab™ , the microViscoStar derives the intrinsic viscosity (IV) of polymers. An inherently valuable physico-chemical property in itself, IV is best utilized together with molar mass information from multi-angle light scattering (SEC-MALS-IV) to derive the hydrodynamic radius, conformation, and branching ratio of a macromolecule in solution.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Visco_Star_pump_pulse_suppression_with_inset_e8c2fbfc18.jpg" alt="Waters microViscoStar: Patented pulse compensation technology in the microViscoStar eliminates pump fluctuations. At the hardware level, the bridge is impedance-matched for dynamic balance, greatly reducing the effect of pump pulses. An additional layer of software filtering eliminates residual pump pulses." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Visco_Star_pump_pulse_suppression_with_inset_e8c2fbfc18.jpg 233w," sizes="100vw" width="348" height="233"><h5>Key benefits of the ViscoStar</h5><ul><li>High sensitivity, equivalent to 5 ng of 100 kDa polystyrene in THF at 1.0 mL/min injected onto a standard GPC column</li><li>High dynamic range of over 135,000:1. The full measurement range corresponds to over 13 mg/mL of 100 kDa polystyrene in THF</li><li>Extended solvent compatibility with all-316 stainless steel transducers</li><li>Temperature range from 4 °C to 70 °C for polymers or proteins that require a range of temperatures</li><li>Minimal band broadening thanks to fast pressure transducers</li><li>Pump pulse suppression to below 4 Pa (hardware alone) or 1 Pa (hardware + software) without loss of chromatographic resolution</li><li>Automated capillary bridge tuning with no moving parts, to guarantee a perfectly balanced bridge, every run</li><li>Enhanced thermal stability with drift of &lt;1.25 Pa/hour</li></ul><h4>SEC-IV without MALS?</h4>Yes, as much as we love MALS for optimal polymer analysis, it's true that there are occasions when it just won't fit the bill.Universal calibration is a parallel technique to SEC-MALS for determining molecular weight, commonly used to characterize linear polymers. While universal calibration overcomes some of the problematic issues associated with column calibration by reference molecules, it does not account for non-ideal column behavior caused by chemical solute-column interactions or hyperbranching.Universal calibration is particularly-well suited to replace MALS for:<ul><li>Strongly fluorescent polymers</li><li>Weakly-scattering polymer/solvent systems with very low dn/dc values</li></ul>The Mark-Houwink-Sakurada relationship makes use of empirical relationships between intrinsic viscosity and molar mass, specific to each polymer and solvent, to estimate molar mass from SEC-IV measurements. Of course, the best way to determine MHS coefficients is to measure them using SEC-MALS-IV and ASTRA™<h4>Specifications</h4><h5>Measurement Capabilities – Differential Viscosity</h5><ul><li>Sensitivity: Detects as little as 5 ng of 100 kDa polystyrene in THF at 1 mL/min under typical UHPLC-SEC conditions.</li><li>Differential Pressure Performance:<ul><li>Noise: &lt; 0.05 Pa</li><li>Range: Up to 6.9 kPa, with overpressure protection</li><li>Drift: &lt; 1.25 Pa/hr</li><li>Linearity: Within 0.5% of full scale</li><li>Dynamic Range: 135,000:1</li></ul></li><li>Capillary Bridge Autobalance: Thermal, leak-free mechanism ensures stable baseline performance.</li><li>Sample Shear Rate: Up to 15,000 Hz with water at 1 mL/min for high-resolution viscosity profiling.</li></ul><h5>Fluidics and Compatibility</h5><ul><li>Maximum Flow Rate: Aqueous and THF: up to 1 mL/min (Note: Using an inline UV detector may reduce allowable flow rate.)</li><li>Delay Volume: 5.4 mL</li><li>Maximum Inlet-to-Outlet Pressure: 3000 kPa (435 psi)</li><li>Wetted Materials: 316 stainless steel, PTFE, zirconium silicate, Kalrez®, Inconel, 26-1 stainless steel, and nickel</li></ul><blockquote>Note: Due to the location of wetted components, this instrument is primarily recommended for use with organic solvents. High-ionic-strength buffers may cause corrosion.</blockquote><h5>Temperature Control</h5><ul><li>Operating Range: 4 °C to 70 °C</li><li>Stability: Maintains temperature within &lt; 0.005 °C</li><li>Ambient Conditions: 0 °C to 40 °C; 20% to 70% relative humidity</li></ul><h5>Electronics and Connectivity</h5><ul><li>Digital Output: 20-bit resolution at 10 Hz</li><li>Auxiliary I/O:<ul><li>Inputs: Autoinject contact closure, Alarm In, and 2 analog inputs (16-bit, ±10 V)</li><li>Outputs: Autoinject retransmit, Alarm Out, Recycle Out</li></ul></li><li>Communication Interface: Ethernet</li></ul><h5>User Interface</h5><ul><li>Front Panel Display: 7” (178 mm) high-resolution, capacitive multi-touch screen for real-time monitoring, configuration, and diagnostics</li></ul><h5>Instrument Dimensions</h5><ul><li>Size: 60 cm (L) × 36 cm (W) × 17 cm (H)</li></ul><h4>Other Viscometers</h4><ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1117">ViscoStar™</a> - A highly sensitive, on-line differential viscometer used in conjunction with SEC-MALS to determine the size and conformation of all types of biopolymers, synthetic polymers and even proteins and peptides.</li><li>The ViscoStar incorporates multiple novel technologies to provide the highest sensitivity, stability and solvent compatibility of any available viscometer for GPC. Its ease-of-use and serviceability make it the perfect companion for Wyatt's DAWN® light scattering and Optilab® refractive index detectors. Temperature-controlled from 4 °C to 70 °C .</li></ul>

Waters/Wyatt Optilab On-line Differential Refractometer

The Waters Optilab is a unique dRI detector for standard HPLC/GPC with 256 times the detection power and 50 times the dynamic range of every other RI detector for chromatography in existence today, making it a valuable addition to any MALS setup.

<h4>Independent of Chromaphores</h4>Independent of chromaphores or fluorophores, differential Refractive Index (dRI) detectors serve as accurate and versatile concentration detectors in all types of solvents. dRI is part of standard instrumentation for a variety of macromolecular characterization techniques including standard chromatography, SEC-MALS, FFF-MALS and CG-MALS.<h4>Unique dRI Detector</h4>The Optilab is a unique dRI detector for standard HPLC/GPC with 256 times the detection power and 50 times the dynamic range of every other RI detector for chromatography in existence today, making it a valuable addition to any MALS setup.<h4>Product Description</h4>Using a combination of cutting-edge semiconductor photodiode technology and proprietary computer algorithms, the Optilab achieves an unprecedented combination of sensitivity and range. These features mean that it addresses both standard chromatographic applications and some challenges unique to light scattering measurements such as high concentrations, determination of sample refractive increments (dn/dc) and solvent refractive index.<h5>Key Benefits</h5><ul><li>Extraordinary dRI measurement range, -0.0047 to +0.0047 RIU (comparable to 25 mg/mL protein in PBS)</li><li>Highly sensitive, ±7.5 x 10 -10 &nbsp;RIU across the entire measurement range</li><li>Measures solvent absolute refractive index, required for MALS calculations</li><li>Measures at the same wavelength as the MALS detector, for maximum accuracy in MALS calculations</li><li>Band broadening &lt; 20 µL preserves SEC resolution</li><li>Temperature range 4 °C to 65 °C for proteins and polymers that require a range of temperatures</li><li>High-resolution, touch-screen front panel displays data graphs and diagnostics, even with the host computer turned off</li></ul><h5>Unparalleled Features</h5>Even though the Optilab offers a dRI measurement range orders of magnitude beyond that of other dRI detectors, unlike other detectors there are no range or gain settings in the Optilab. The full range of instrument detection is always present, and the full sensitivity exists over the entire range.The Optilab can also do something no other on-line refractive index detector can: it can measure the absolute refractive index of a solution. In addition, it can measure the dn/dc of a solvent at the same wavelength of light as the light scattering instrument. And just to make sure it can't be matched, you can replace the light source in the Optilab for other wavelengths (e.g., 690, 633, 488, etc.) in just minutes!The Optilab can go below ambient temperatures as easily as above ambient. No hassle temperature control can be programmed from 4 °C to 65 °C. Compatible with all HPLC systems.<h4>Specifications</h4><h5>Measurement Capabilities – Differential Refractive Index</h5>Standard Optilab Configuration<ul><li>Measurement Range: –0.0047 to +0.0047 RIU</li><li>Peak-to-Peak Noise: ±7.5 × 10⁻¹⁰ RIU (Measured per ASTM-E1303-95 at 25 °C)</li></ul>High Concentration (HC) Option<ul><li>Measurement Range: –0.0026 to +0.034 RIU</li><li>Peak-to-Peak Noise: ±1.5 × 10⁻⁹ RIU (Optimized for higher concentration samples)</li><li>Response Time: User-selectable from 0.1 to 5 seconds</li><li>Absolute Refractive Index Measurement Range: 1.2 to 1.8 RIU</li><li>Absolute RI Sensitivity: ±0.002 RIU</li></ul>Fluidics and Flow Properties<ul><li>Band Broadening: &lt;12 µL</li><li>Fill Volume (Inlet Tubing + Flow Cell): 51.4 µL</li><li>Outlet Tubing Volume (0.030" ID): 370 µL</li></ul>Pressure Ratings<ul><li>Inlet Back Pressure (0.5 mL/min H₂O @ 20 °C): &lt;22 psi (1.5 bar)</li><li>Max Outlet Back Pressure: 30 psi (2 bar)</li></ul>Temperature Control<ul><li>Sample Temperature Control Range: 4 °C to 65 °C</li><li>Regulation Stability: ±0.005 °C</li></ul>Light Source Options<ul><li>Standard: 660 nm</li><li>HC Model (Optional): 488 nm, 785 nm, or 940 nm</li></ul>Safety Features<ul><li>Built-in vapor and liquid leak sensors for enhanced lab safety</li></ul>Electronics and Connectivity<ul><li>Digital Output: 22+ bit resolution @ 10 Hz</li><li>Analog Output: ±10 V or ±1 V, 18-bit resolution</li><li>Computer Interface: Ethernet</li></ul>Auxiliary I/O Ports<ul><li>Inputs:<ul><li>Analog In (16-bit, ±10 V A/D)</li><li>Zero dRI</li><li>Purge</li><li>Recycle In</li><li>Autoinject In</li><li>Alarm In</li></ul></li><li>Outputs:<ul><li>Autoinject Retransmit</li><li>Alarm Out</li><li>Recycle Out (controls Orbit™ valve switching)</li></ul></li></ul>User Interface<ul><li>Front Panel Display: 7” (178 mm) high-resolution multi-touch screen for viewing signals, diagnostics, and adjusting instrument settings</li></ul>Instrument Dimensions<ul><li>Size: 58 cm (L) × 36 cm (W) × 18 cm (H)</li></ul><h4>Other Refractive Index Detectors</h4><ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1269">microOptilab™</a> - The first RI detector specifically designed for use with all UHPLC systems.</li></ul>

Waters/Wyatt microOptilab On-line Differential Refractometer

The Waters microOptilab brings the universal detection capabilities, unsurpassed concentration range, and superb sensitivity and linearity

<h4>Independent of Chromaphores</h4>Independent of chromaphores or fluorophores, differential Refractive Index (dRI) detectors measure concentrations of all types of samples in almost all solvents. The microOptilab brings the universal detection capabilities, unsurpassed concentration range, and superb sensitivity and linearity – familiar from the Optilab™ – to the domain of UHPLC.<h4>SEC-MALS with UHPLC</h4>Like standard SEC, UHPLC-SEC analysis relying on column calibration with molecular standards is unreliable when the standards do not accurately reflect your samples in terms of conformation, non-ideal (e.g., hydrophobic) column interactions or reversible association. SEC-MALS employs a microDAWN™ MALS detector downstream of the SEC column and UV detector, to determine molar mass / molecular weight distributions of macromolecules independently of column calibration.Refractive index detection is an important component of any SEC-MALS system, and necessary for analyzing conjugated proteins or polymers devoid of chromaphores. The microOptilab connects with the microDAWN MALS detector for a complete UHP-SEC-MALS setup that transfers the many benefits of SEC-MALS analysis to the realm of UHPLC.<h5>Key benefits</h5><ul><li>Very low band broadening, &lt; 4 µL, to maintain the resolution of very narrow UHPLC peaks</li><li>Extraordinary dRI measurement range, -4.7 x 10 -3 &nbsp;to +4.7 x 10 -3 &nbsp;RIU (comparable to 25 mg/mL protein in PBS)</li><li>Highly sensitive, ± 1.5 x 10 -9 &nbsp;RIU across the entire measurement range</li><li>Measures solvent refractive index, require for MALS calculations</li><li>Measures at the same wavelength as the MALS detector, for maximum accuracy in MALS calculations</li><li>Temperature range 4 °C to 65 °C for proteins and polymers that require a range of temperatures</li><li>High-resolution, touch-screen front panel displays data graphs and instrument diagnostics, even with the host computer turned off</li></ul><h5>Unparalleled features</h5><ul><li>Considering the extremely small peak volumes of UHPLC, band broadening in the microOptilab is kept to the absolute minimum, at less than 4 µL, as compared to 20 - 40 µL or more for standard RI detectors. As a result, the superior resolution from UHPLC columns and instruments will not be compromised with the microOptilab RI detector.</li><li>Even though the microOptilab offers a dRI measurement range orders of magnitude beyond that of other UHPLC dRI detectors, unlike other detectors there are no range or gain settings in the microOptilab. The full range of instrument detection is always present, and the full sensitivity exists over the entire range. The small flow cell and proprietary temperature regulation enable stable RI baselines and signals which further enhance the detector's sensitivity.</li><li>Unlike all other dRI detectors, the microOptilab also measures absolute refractive index in order to determine solvent RI, necessary in light scattering calculations and useful in assessing the accuracy of mixing of solvent gradients.</li><li>The microOptilab can be operated below ambient temperatures as easily as above ambient. No hassle temperature control can be programmed down to 4 °C or as high as 65 °C.</li><li>The microOptilab is compatible with all UHPLC systems.</li></ul><h4>Specifications</h4><h5>Measurement Capabilities – Differential Refractive Index</h5><ul><li>Differential RI Measurement Range: –0.0047 to +0.0047 RIU</li><li>Peak-to-Peak Noise: ±1.5 × 10⁻⁹ RIU (Measured per ASTM-E1303-95 at 25 °C with a 0.5 sec collection interval)</li><li>Response Time: User-selectable from 0.04 to 5 seconds</li><li>Absolute Refractive Index Range: 1.2 to 1.8 RIU</li><li>Absolute RI Sensitivity: ±0.002 RIU</li></ul>Fluidics and Flow Properties<ul><li>Band Broadening: &lt;4 µL (at 0.3 mL/min)</li><li>Fill Volume (Inlet Tubing + Flow Cell): 13.7 µL</li><li>Outlet Tubing Volume (0.030” ID): 228 µL</li></ul>Pressure Ratings<ul><li>Inlet Back Pressure (0.5 mL/min H₂O @ 20 °C): &lt;320 psi (22 bar)</li><li>Maximum Permissible Outlet Pressure: 30 psi (2 bar)</li></ul>Temperature Control<ul><li>Control Range: 4 °C to 65 °C</li><li>Stability: ±0.005 °C for precise thermal regulation</li></ul>Optical Source and Safety<ul><li>Light Source: 660 nm wavelength</li><li>Safety Sensors: Integrated vapor and liquid leak detection</li></ul>Electronics and Connectivity<ul><li>Digital Output Rate: 25 Hz</li><li>Analog Output: ±10 V or ±1 V, 18-bit resolution</li><li>Computer Interface: Ethernet for seamless data connectivity</li></ul>Auxiliary I/O Ports<ul><li>Inputs:<ul><li>Analog In (16-bit, ±10 V A/D)</li><li>Zero dRI</li><li>Purge</li><li>Recycle In</li><li>Autoinject In</li><li>Alarm In</li></ul></li><li>Outputs:<ul><li>Autoinject Retransmit</li><li>Alarm Out</li><li>Recycle Out (Orbit™ valve switching)</li></ul></li></ul>User Interface<ul><li>Display: 7” (178 mm) high-resolution multi-touch screen for viewing live signals, diagnostics, and configuring instrument settings</li></ul>Instrument Dimensions<ul><li>Size: 58 cm (L) × 36 cm (W) × 18 cm (H)</li></ul><h4>Other Refractive Index Detectors</h4><ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1268">Optilab™</a> - A unique on-line differential refractometer for measuring concentration of any macromolecule, regardless of chromophores. Temperature controlled from 4 °C to 65 °C. The high-concentration option accommodates protein concentration up to 180 mg/mL.</li></ul>

ECOM LED20M FIX Dual UV Detector with display

The LED20M FIX Dual UV Detector with a display uses Light Emitting Diodes (LED) as the light source. It is used for flash chromatography.

<div style="display:block;" aria-labelledby="tab_item-0">The LED20M FIX Dual UV Detector with a display uses Light Emitting Diodes (LED) as the light source. It is used for flash chromatography.<h3>Why choose LED20M FIX detectors for your application</h3><ul><li>The LED detectors allow easy and convenient detection in the UV-VIS range. They are manufactured in single or dual channel models with fixed wavelength setup.</li><li>The detectors are widely used in chromatography techniques using gravity glass columns for purification and isolation of organic small molecules and other compounds of interest. Long-lasting and reliable light source is provided by LED.</li><li>The optical flow cell is easily accessible and replaceable, this feature allows flexible choice of detection sensitivity if required. Low cell heating due to low power dissipation of LEDs makes this detector ideal for applications where analytes may be susceptible to degradation due to elevated temperatures. Absorbance information is displayed in detail on the integrated OLED display in numerical and graphical formats.</li><li>The units have convenient USB-C connectivity and power. When the detector is connected to a PC, the recorded data can be stored and processed using the ECOMAC software. ECOMAC basic software license is available with the price of the product without any additional fees. All these features and capabilities allow LED20M FIX to be an affordable, cost-effective, reliable and robust choice of an UV-VIS detector.</li></ul><h4>Wavelengths</h4><ul><li>The dual UV detector version measures at two fixed wavelengths, which are adjusted in production and given by the built-in LEDs.</li><li>By default, diodes with wavelengths of 255 and 280 nm are used. Optionally, the customer can select a wavelength in the range of 255–⁠⁠⁠⁠⁠⁠600 nm in steps of 5 nm.</li></ul><h4>Control</h4><ul><li>The detector can work without any additional SW support, but it is also possible to interconnect it via USB-C cable to a PC with ECOMAC SW, to get a data set for later use or to get reports for unit diagnostics.</li><li>The unit has an innovative PCB board that powers the LEDs, controls the unit, and has many new features, including higher sampling speed.</li></ul><h4>Key features and benefits</h4><ul><li>OLED display</li><li>Numerical and graphical view mode</li><li>Long lifetime of the LED light source</li><li>Low cell heating due to low power losses of the LEDs</li><li>USB C powering and communication port</li><li>ECOMAC Basic software for free</li><li>Autozero function</li><li>Easy flow cell replacement</li><li>Small dimensions</li><li>ECOMAC SW - &nbsp;sophisticated software for data acquisition and for diagnostics</li></ul></div>

ECOM LED20M FIX Single UV Detector with display

The LED20M FIX Single UV Detector with a display uses Light Emitting Diodes (LED) as the light source. It is used for flash chromatography.

<div style="display:block;" aria-labelledby="tab_item-0">The LED20M FIX Single UV Detector with a display uses Light Emitting Diodes (LED) as the light source. It is used for flash chromatography.<h3>Why choose LED20M FIX detectors for your application</h3><ul><li>The LED detectors allow easy and convenient detection in the UV-VIS range. They are manufactured in single or dual channel models with fixed wavelength setup.</li><li>The detectors are widely used in chromatography techniques using gravity glass columns for purification and isolation of organic small molecules and other compounds of interest. Long-lasting and reliable light source is provided by LED.</li><li>The optical flow cell is easily accessible and replaceable, this feature allows flexible choice of detection sensitivity if required. Low cell heating due to low power dissipation of LEDs makes this detector ideal for applications where analytes may be susceptible to degradation due to elevated temperatures. Absorbance information is displayed in detail on the integrated OLED display in numerical and graphical formats.</li><li>The units have convenient USB-C connectivity and power. When the detector is connected to a PC, the recorded data can be stored and processed using the ECOMAC software. ECOMAC basic software license is available with the price of the product without any additional fees. All these features and capabilities allow LED20M FIX to be an affordable, cost-effective, reliable and robust choice of an UV-VIS detector.</li></ul><h3>Wavelengths</h3><ul><li>The single UV detector version measures at 1 fixed wavelength, which is adjusted in production and given by the built-in LEDs.</li><li>By default, diodes with wavelengths of 255 or 280 nm are used. Optionally, customers can select a wavelength within the range of 255–⁠⁠⁠⁠⁠⁠600 nm in steps of 5 nm.</li></ul><h3>Control</h3><ul><li>The detector can work without any additional SW support, but it is also possible to interconnect it via USB-C cable to a PC with ECOMAC SW, to get a data set for later use or to get reports for unit diagnostics.</li><li>The unit has an innovative PCB board that powers the LEDs, controls the unit, and has many new features, including higher sampling speed.</li></ul><h3>Key features and benefits</h3><ul><li>Practical OLED display</li><li>Numerical and graphical view mode</li><li>Long lifetime of the LED light source</li><li>Low cell heating due to low power losses of the LEDs</li><li>USB -C powering and communication port</li><li>Autozero function</li><li>Easy flow cell replacement</li><li>Small dimensions</li><li>ECOMAC SW - &nbsp;sophisticated software for data acquisition and for diagnostics</li></ul>Note: A preparative cell PFC 200 Basic is supplied with the unit. Other flow cells are available at request.</div>

ECOM LED20G Dual UV Detector

LED20G Dual UV detector for preparative and flash chromatography. ECOM's unique patented technology radically improves the detectors´ features. LEDs are used as the source of light.

<div style="display:block;" aria-labelledby="tab_item-0">LED20G Dual UV LED detector for preparative and flash liquid chromatography. LEDs (Light Emitting Diodes) are used as the light source. A unique and patented ECOM technology radically improves the detector characteristics.&nbsp;The LEDs themselves typically have a peak wavelength with a tolerance of +/- 5 nm and a spectral half-width of 10-20 nm, which is unacceptable for some applications, as e.g. for FPLC. This ECOM solution, however, allows the spectral width to be narrowed and, thanks to our patented technology, the exact wavelength to be selected from the LED spectrum.This version of the dual UV detector measures at two fixed wavelengths given by the installed LEDs.The default wavelengths are 254 and 280 nm. Optionally, the customer can select a wavelength in the range 254-600 nm in 1 nm steps.The unit is controlled by an innovative printed circuit board that powers the LEDs, controls the unit, and has many new features including higher sampling speed.<h3>Key features and benefits</h3><ul><li>Sharp, high, and symmetrical peaks thanks to the ECOM patented technology</li><li>Excellent linearity</li><li>Excellent price-performance ratio</li><li>Compact device dimensions</li><li>Low cell heating due to LED low power supply (0.7 W) allows use for peptide analysis or FPLC</li><li>Easy flow cell replacement</li><li>Higher sampling speed</li><li>Sophisticated diagnostic software</li><li>Diodes with wavelengths of 254 and 280 nm and a PFC cell with an optical path length of 2 mm are used as standard.</li><li>Other cells and wavelengths on request.</li></ul><h3>Parameters</h3><ul><li>Number of channels (Signals): Two fix wavelength</li><li>Typical spectral half-width&nbsp;: 4</li><li>Light source: LEDs</li><li>Noise level at test cell (254 nm, TC 0.75 s): ± 10x10-6 AU</li><li>Drift at test cell (254 nm after 1 h): 1x10-3 AU/hr</li><li>Communication: Remote digital I/O</li><li>Power supply: 12-24 V DC</li><li>Power input: 2 W</li><li>Materials in contact with mobile phase: FEP; fused silica, stainless steel (cell)</li><li>Communication interface: USB-C</li><li>Optical cables: no</li><li>Dimensions W x H x D: 193 x 70 x 40 mm (7.60 x 2.76 x 1.57 in)</li><li>Weight: 0.66 kg (1.46 Ibs)</li></ul></div>

ECOM TOY18DAD 600 H Four Channel UV/PDA Detector

Four Channel version of our detector measures at four wavelengths simultaneously with possibility to see current scan and with built-in lamp working hours counter.

<div style="display:block;" aria-labelledby="tab_item-0">TOY18DAD 600 H Four Channel UV Detector is a standalone UV-VIS detector suited for preparative and flash chromatography with diode array (DAD) in range 200 – 600 nm.Four&nbsp;Channel&nbsp;version measures at&nbsp;four wavelengths simultaneously&nbsp;with possibility to see&nbsp;current scan.More wavelengths or scan are used in liquid chromatography to verify purity of analyzed samples or in situations when some peaks absorb on different wavelengths.<h4>Most important features of TOY18DAD H detectors:</h4><ul><li>built-in lamp working hours counter</li><li>easy replacement of flow cell</li><li>measuring at more wavelengths simultaneously</li><li>sophisticated diagnostic software</li></ul><h4>Parameters:</h4><ul><li>Number of channels (Signals): 4</li><li>Scan: Informative 200 – 600 nm</li><li>Number of CCD elements: 256</li><li>Communication: RS232, Ethernet (LAN), USB</li><li>Accuracy of adjustment: ± 1 nm</li><li>Typical spectral half-width: 10 nm</li><li>Reproducibility: ± 0.5 nm</li><li>Noise (Test cell, 254nm, TC 2s, 10 Hz): ± 5 x 10-5 AU</li><li>Drift (Test cell, 254nm): 1 x 10-3 AU/hr</li><li>Time constant: Time constant (T63) 0.5 s, 0.75 s, 1.0 s, 2.0 s, 4.0 s, 8.0 s, 16.0 s, 0.2 s, 0.1</li><li>Communication: RS232,Ethernet (LAN),USB</li><li>Power supply: 100-240V 50/60Hz</li><li>Power input: 100 VA (120 VA for upcoming version)</li><li>Materials in contact with mobile phase: FEP; fused silica, stainless steel, PEEK, KEL-F</li><li>Optical cables: no</li><li>Dimensions W x H x D: 280 x 135 x 463 mm (11.02 x 5.32 x 18.23 in)</li><li>Weight: 7.5 kg (16.53 lb)</li></ul></div>

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