Separation Sciences in the Czech Republic: From Historical Foundations to Recent Advances

A Liquid–Liquid Extraction Method for Measuring Ultrashort PFCAs and Longer-Chain PFAS in Water

<p><strong>In the week of August 24, the following webinars await you in the field of liquid phase and especially HPLC and LC/MS.</strong></p><blockquote><h4><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/webinars"><strong>👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</strong></a></h4><p><strong>👉 Search and filter in the largest global database</strong> with over <strong>5 500 GC, LC, MS and spectroscopy webinars</strong>.</p></blockquote><h5><strong>1. Separation Science: From Downtime to Data: How Long-Life LC Columns Transform High-Throughput Labs</strong></h5><ul><li>Tu, 25.8.2026 14:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/webinar/6447">Registration</a></li></ul><p>Extend your LC-MS/MS column lifetime. Learn how Phenomenex Endrix columns reduce downtime and lower cost per injection when analyzing complex matrices.</p><h5><strong>2. SCIEX: Distinguishing Ile/Leu variant ligands in the immunopeptidome using hybrid ExCID fragmentation on SCIEX accurate mass instrument</strong></h5><ul><li>We, 26.8.2026 05:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/webinar/6449">Registration</a></li></ul><p>Differentiating Ile and Leu variants in immunopeptides can be challenging. Discover how SCIEX ZenoTOF hybrid ExCID (EAD+CID) fragmentation and optimized chromatography help resolve these variants.</p><h5><strong>3. Phenomenex: Fundamentals First Bio Series: Understanding Magnetic Bead-Based Extraction Techniques</strong></h5><ul><li>We, 26.8.2026 10:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/webinar/6437">Registration</a></li></ul><p>Compare magnetic beads with traditional sample preparation and learn how to improve selectivity, scalability, and reproducibility when isolating peptides, oligonucleotides, and mRNA for LC-MS.</p><h5><strong>4. Thermo Fisher Scientific: Simplifying Transcriptomics for Clinical Research with Ion AmpliSeq™ Technology</strong></h5><ul><li>We, 26.8.2026 17:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/webinar/6451">Registration</a></li></ul><p>Discover how Ion AmpliSeq Transcriptome technology simplifies gene expression profiling with a fast two-day turnaround for clinical research workflows.</p><h5><strong>5. Waters Corporation: Foundations of a Sustainable, High-Performing QA Program</strong></h5><ul><li>We, 26.8.2026 17:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/webinar/6448">Registration</a></li></ul><p>Build a sustainable, high-performing QA program in your lab. Learn the four pillars of data quality: method validation, analyst competency, control charting, and certified reference materials.</p><h5><strong>6. Waters Corporation: Tiny Plastics, Big Questions: Advances in Microplastics &amp; Nanoplastics Analysis</strong></h5><ul><li>We, 26.8.2026 19:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/webinar/6450">Registration</a></li></ul><p>Explore complementary DLS and AF4-MALS techniques for nanoplastic fractionation together with high-throughput screening approaches for microplastics in drinking water.</p><h5><strong>7. Thermo Fisher Scientific: Tips and Tricks II: Optimising LC Column Separation</strong></h5><ul><li>Th, 27.8.2026 09:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/webinar/6453">Registration</a></li></ul><p>Learn how mobile phase composition, pH, buffer selection, and column selectivity influence chromatographic resolution, analyte recovery, and reproducibility.</p><h5><strong>8. Thermo Fisher Scientific: Tips to power up your LC with Chromeleon software</strong></h5><ul><li>Th, 27.8.2026 11:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/webinar/6452">Registration</a></li></ul><p>Discover how Thermo Scientific Chromeleon software can increase sample throughput, automate data processing, and maximize productivity with Vanquish UHPLC systems.</p><h5><strong>9. Separation Science: The TFA &amp; DFA Challenge Solved: Ultra-Sensitive Detection with End-to-End Automation</strong></h5><ul><li>Th, 27.8.2026 11:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/webinar/6424">Registration</a></li></ul><p>Master ultra-short-chain PFAS analysis with an automated SCIEX LC-MS/MS workflow designed for sensitive TFA and DFA quantification.</p><h5><strong>10. Technology Networks: Tech Spotlight: Mass Spectrometry 2026</strong></h5><ul><li>Th, 27.8.2026 17:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/webinar/6409">Registration</a></li></ul><p>Explore innovations in mass spectrometry for omics and learn how advances in ion mobility and data analysis are accelerating biomarker discovery.</p><h5><strong>11. Agilent Technologies: Absolute Specular Reflectance made Easy in UV-Vis-NIR</strong></h5><ul><li>Th, 27.8.2026 20:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/webinar/6439">Registration</a></li></ul><p>Learn how the Cary 7000 enables accurate specular reflectance and transmission measurements without swapping accessories, supporting fast and precise testing across different angles.</p>

Webinars LabRulezLCMS Week 35/2026

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Thermo Scientific Nanospray Flex Ion Source 

Thermo Scientific™ Nanospray Flex™ Ion Source is a flexible nano-electrospray ion source for LC-MS, delivering stable ionization, high sensitivity, and seamless integration with online and offline nano-ES workflows.

<p><strong>Thermo Scientific™ Nanospray Flex™ Ion Source is a nano-electrospray ion source designed to maximize LC-MS sensitivity while maintaining simple operation and exceptional flexibility. Developed for nanoflow LC-MS applications, it provides stable nano-electrospray ionization, low-flow operation, and flexible integration with a wide range of columns and emitters. The complete system is supplied with all required accessories for immediate installation.</strong></p><h3><strong>Key Features</strong></h3><h4><strong>High-Sensitivity Nano-ESI</strong></h4><ul><li>Maximizes LC-MS sensitivity using stable nanoflow electrospray ionization</li><li>Supports nanoscale flow rates for efficient ionization and reduced sample consumption</li><li>Delivers highly stable spray performance for long analytical runs and stable spray performance during extended runs</li></ul><h4><strong>Flexible Workflow</strong></h4><ul><li>Single configuration for all online nanoflow LC-MS applications</li><li>Quickly switches between online LC-MS and offline nano-ES workflows</li><li>DirectJunction™ adaptor supports a wide range of column and emitter connections</li><li>Compatible with both stainless steel and glass emitters</li></ul><h4><strong>Easy Operation</strong></h4><ul><li>Precision X-Y-Z manipulator for accurate emitter positioning</li><li>Sliding rail design allows fast emitter access and replacement</li><li>Integrated camera, monitor, and illumination simplify emitter alignment</li><li>Supplied as a complete kit with accessories for immediate installation</li></ul><h3><strong>Instrument Compatibility</strong></h3><h4><strong>Original Nanospray Flex Ion Source</strong></h4><ul><li>Thermo Scientific™ LCQ Deca XP MAX™, LTQ™-series, and Velos™-series ion trap mass spectrometers</li><li>Thermo Scientific™ LTQ Orbitrap™-series and Orbitrap Velos™-series hybrid ion trap-Orbitrap mass spectrometers</li><li>Thermo Scientific™ Exactive™-series Orbitrap mass spectrometers</li><li>Thermo Scientific™ Q Exactive™-series hybrid quadrupole-Orbitrap mass spectrometers</li><li>Thermo Scientific™ TSQ Quantum™-series and TSQ Vantage™ triple-stage quadrupole mass spectrometers</li></ul><h4><strong>Nanospray Flex NG</strong></h4><ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/562"><strong>Thermo Scientific™ Orbitrap Fusion™ Tribrid™ mass spectrometer</strong></a></li><li>Thermo Scientific™ TSQ Endura™ triple-stage quadrupole mass spectrometer</li></ul>

Thermo Scientific EASY-Spray Sources

Thermo Scientific™ EASY-Spray™ Sources are integrated nano-electrospray ion sources for nano-LC-MS featuring a temperature-controlled column-emitter assembly for stable ionization, excellent reproducibility, and simplified installation.

<p><strong>Thermo Scientific™ EASY-Spray™ Sources are integrated nano-electrospray ion sources designed for nanoflow LC-MS. Their temperature-controlled column-emitter assembly and single nanoViper™ connection simplify nanoLC-MS operation while delivering highly reproducible separations, stable spray performance, and high LC-MS sensitivity</strong></p><h4><strong>Integrated Design</strong></h4><ul><li>Integrated temperature-controlled column and emitter assembly</li><li>Single nanoViper™ connection between the LC system and ion source</li><li>Integrated zero-dead-volume (ZDV) connections minimize dead volume</li><li>Simple plug-and-spray installation with quick column replacement</li></ul><h4><strong>Chromatographic Performance</strong></h4><ul><li>Stable nano-electrospray ionization for reliable LC-MS analysis</li><li>Supports long columns and small particle sizes for high peak-capacity separations</li><li>Column heating (30–60 °C) reduces solvent viscosity and backpressure</li><li>Ultra-sharp chromatographic peaks improve separation efficiency</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_EASY_Spray_Sources_4_361e3bad42.jpg" alt="Thermo Scientific EASY-Spray Sources: The entire assembly is designed for heavy use so you can utilize the full pressure range of your UHPLC front-end (up to 1000 bar) and benefit from small particles and long columns. Longer columns and longer gradients both contribute to more identifications." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_EASY_Spray_Sources_4_361e3bad42.jpg 229w," sizes="100vw" width="921" height="628"></p><h4><strong>Reproducibility</strong></h4><ul><li>Stable performance during extended analytical operation</li><li>Excellent run-to-run reproducibility</li><li>Outstanding column-to-column reproducibility for large studies and multi-site laboratories</li></ul><h4><strong>Ease of Use</strong></h4><ul><li>Plug-and-spray operation requiring minimal setup</li><li>Integrated camera provides an illuminated, magnified view of the emitter tip</li><li>Eliminates the most error-prone nanoLC connections</li></ul><h4><strong>Compatibility</strong></h4><p>Compatible with Thermo Scientific EASY-Spray columns and selected Thermo Scientific nanoLC systems and mass spectrometers, including:</p><ul><li>Thermo Scientific™ LCQ Deca XP MAX™, LTQ™-series, and Velos™ series ion trap mass spectrometers</li><li>Thermo Scientific™ LTQ Orbitrap™-series and Orbitrap Velos™ series hybrid ion trap-Orbitrap mass spectrometers</li><li>Thermo Scientific™ Exactive™ series Orbitrap mass spectrometers</li><li>Thermo Scientific™ Q Exactive™ series hybrid quadrupole-Orbitrap mass spectrometers</li><li>Thermo Scientific™ TSQ Quantum™ series and TSQ Vantage™ triple-stage quadrupole mass spectrometers</li></ul><p>The EASY-Spray NG ion source works in conjunction with the latest next-generation Thermo Scientific mass spectrometers:</p><ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/562"><strong>Thermo Scientific™ Orbitrap™ Fusion™ Tribrid™ Mass Spectrometer</strong></a></li><li>Thermo Scientific™ TSQ Endura™ Triple-stage Quadrupole Mass Spectrometer</li><li>Thermo Scientific™ TSQ Quantiva™ Triple-stage Quadrupole Mass Spectrometer</li></ul>

Thermo Scientific OptiSpray Ion Source

The Thermo Scientific™ OptiSpray™ Ion Source is an intelligent ESI interface for nano- and capillary LC-MS, combining automated spray optimization, high sensitivity, reproducibility, and easy operation with the OptiSpray™ Cartridge system.

<p><strong>The Thermo Scientific™ OptiSpray™ Ion Source is an intelligent electrospray ionization interface designed to simplify the acquisition of high-quality, reproducible nano- and capillary LC-MS data. Compatible with the </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/398"><strong>Thermo Scientific™ Vanquish™ Neo UHPLC system </strong></a><strong>and the </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products?category=5&amp;manufacturerItems=3"><strong>Thermo Scientific mass spectrometers </strong></a><strong>portfolio, it combines automated spray optimization with cartridge-based nano and capillary columns to deliver high sensitivity, quantitative accuracy, precision, and robust performance for discovery and targeted assays.</strong></p><h4><strong>High Performance</strong></h4><p>The OptiSpray™ ion source combines optimized fluidics with integrated temperature and sheath gas control to ensure stable, reproducible electrospray ionization. Automated spray positioning helps deliver reproducible, high-quality analytical results with or without the FAIMS interface.</p><h4><strong>Simple and Automated Operation</strong></h4><p>Designed for ease of use, the OptiSpray™ system features plug-and-play cartridge installation that virtually eliminates manual setup of nano and capillary columns. Automated spray optimization further simplifies operation, while onboard cartridge memory stores cartridge properties, usage data, and previous source settings, enabling rapid setup and consistent ESI performance over time.</p><h4><strong>Reliable and Reproducible Results</strong></h4><p>The source enhances robustness by automatically moving the spray to an inactive position between injections, helping maintain a cleaner MS system. Exchangeable emitters extend column lifetime, while automated spray positioning, cartridge memory, and integrated nebulization gas boost contribute to run-to-run and intercolumn reproducibility.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Opti_Spray_Ion_Source_2_fd937ef73f.jpg" alt="Thermo Scientific OptiSpray Ion Source" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Opti_Spray_Ion_Source_2_fd937ef73f.jpg 156w," sizes="100vw" width="650" height="650"></p><h3><strong>Key Features</strong></h3><ul><li>Intelligent electrospray ionization interface for nano- and capillary LC-MS</li><li>Automated spray optimization for consistent ESI performance</li><li>Plug-and-play cartridge installation with minimal manual setup</li><li>Optimized fluidics with integrated temperature and sheath gas control</li><li>Automated spray positioning</li><li>Compatible with or without the FAIMS interface</li><li>Onboard cartridge memory storing cartridge properties, usage data, and previous source settings</li><li>Automatic inactive spray position between injections for improved system robustness</li><li>Exchangeable emitters to extend column lifetime</li><li>Integrated nebulization gas boost for improved reproducibility</li><li>Designed for discovery and targeted assays</li></ul>

Products from category Spare parts for LC/MS - page 1

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Webinars LabRulezLCMS Week 35/2026

A Liquid–Liquid Extraction Method for Measuring Ultrashort PFCAs and Longer-Chain PFAS in Water

Separation Sciences in the Czech Republic: From Historical Foundations to Recent Advances