<p><strong>Solid Phase Extraction (SPE) is one of the most highly selective sample preparation methods, meaning that the targeted analytes and their matrices must be considered when choosing the correct SPE sorbent and format. Drying down the sorbent before elution is an important step.</strong></p><ul><li>Wash solvents are used to flush out unwanted compounds (i.e., contaminants). If the wash solvent is not completely removed, then residual wash solvent could contaminate the final elution.</li><li>If you do not dry the SPE sufficiently, it could make the final solution less concentrated and result in a reduction in sensitivity.</li><li>Drying helps physically break down the interactions between the sorbent and analyte for a more concentrated extract.</li></ul><p>After the wash solvent has been passed through the cartridge, continue to apply negative pressure (vacuum) or positive pressure. Use this pressure to dry the cartridge for 2 to 5 minutes (or until dry). Turn off the pressure and wipe the tips of the manifold needles to remove any residual solvent.</p><h5><strong>Notes</strong></h5><ol><li><strong>Reproducibility:</strong> Drying removes traces of residual sample/matrix and wash solvent from the sorbent. This produces a more concentrated final extract with a consistent volume and composition and yields better reproducibility and higher recoveries.</li><li><strong>Immiscibility:</strong> Drying is especially critical when using elution solvents that are immiscible with water (e.g. hexane, ethyl acetate, and methylene chloride). Residual water in the sorbent bed may prevent dissolution of the analyte in the elution solvent, resulting in low recoveries and irreproducibility.</li><li><strong>Over-drying: </strong>Avoid over-drying the sorbent, since in some cases, analyte recovery may decrease with excessive vacuum or drying times above 5 minutes. Dry cartridges look distinctly different from moist ones. Make a note of the cartridge appearance before and after conditioning. Also, you could touch the cartridge while it is drying; wet cartridges feel colder than dry cartridges.&nbsp;</li></ol>

Why Is It Necessary to Dry the SPE Sorbent Before Elution?

<h3><strong>Mastering Ion-Pair Reversed-Phase Chromatography for Oligonucleotide Analysis</strong></h3><h4><strong>Why Purity Is Critical in the Oligonucleotide Era</strong></h4><p>Oligonucleotides — short, synthetic strands of DNA or RNA — are central to modern biotechnology. They power gene therapies, advanced diagnostics, and cutting-edge molecular research. However, before these molecules can be used in clinical or research settings, their purity and structural integrity must be thoroughly verified. High-resolution chromatographic analysis plays a crucial role in ensuring quality and safety.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_Figure_1_Separation_Example_of_Oligonucleotides_5577514561.jpg" alt="KNAUER: Figure 1 - Separation Example of Oligonucleotides." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_Figure_1_Separation_Example_of_Oligonucleotides_5577514561.jpg 245w," sizes="100vw" width="1024" height="368"></p><h4><strong>Understanding Ion-Pair Reversed-Phase (IP-RP) Chromatography</strong></h4><p>For scientists involved in oligonucleotide synthesis and characterization, Ion-Pair Reversed-Phase Chromatography (IP-RP) is one of the most effective analytical tools available.</p><p>Unlike separation techniques that rely solely on charge differences, IP-RP combines:</p><ul><li>Ionic interactions</li><li>Hydrophobic interactions</li></ul><p>This dual retention mechanism enables exceptional resolution — even for oligonucleotides that differ by only a single nucleotide or subtle chemical modification. Whether assessing synthesis efficiency or purifying therapeutic-grade material, IP-RP provides reliable, reproducible separations.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_Figure_2_Overview_of_IP_RP_Mode_prinicple_ecd54b6e9c.jpg" alt="KNAUER: Figure 2 - Overview of IP-RP Mode prinicple." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_Figure_2_Overview_of_IP_RP_Mode_prinicple_ecd54b6e9c.jpg 245w," sizes="100vw" width="1024" height="456"></p><h4><strong>The Principle Behind Ion-Pairing</strong></h4><p>Oligonucleotides possess a highly negatively charged phosphate backbone. In a traditional reversed-phase system, such hydrophilic, charged molecules would show little retention.</p><p>IP-RP overcomes this limitation by introducing a positively charged ion-pairing reagent into the mobile phase. The cation associates with the negatively charged oligonucleotide, forming a transient ion pair with increased hydrophobic character. This modified complex can now interact with the hydrophobic stationary phase.</p><p>Retention strength depends on:</p><ul><li>The hydrophobicity of the ion-pair reagent</li><li>The strength of ionic interaction</li><li>The applied organic gradient</li></ul><p>During gradient elution (commonly using acetonitrile), analytes are released in a controlled manner according to size, sequence, and chemical modifications.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_Figure_3_Ion_Pair_Reversed_Phase_Principle_9a4fcd12f2.jpg" alt="KNAUER: Figure 3 - Ion-Pair Reversed Phase Principle." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_Figure_3_Ion_Pair_Reversed_Phase_Principle_9a4fcd12f2.jpg 245w," sizes="100vw" width="1024" height="393"></p><h4><strong>Choosing the Right Ion-Pair Reagent</strong></h4><p>Successful IP-RP separation depends heavily on selecting an appropriate ion-pair reagent. Two key factors determine retention behavior:</p><ol><li>Alkyl chain length</li><li>Charge density</li></ol><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_Figure_4_Ion_Pair_Classification_eaad172a4e.jpg" alt="KNAUER: Figure 4 - Ion-Pair Classification." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_Figure_4_Ion_Pair_Classification_eaad172a4e.jpg 245w," sizes="100vw" width="1024" height="398"></p><h4><strong>Strong Cationic Ion-Pair Reagents</strong></h4><p>Ion-pair reagents with longer alkyl chains provide stronger hydrophobic interactions and increased retention. A widely used example is tetrabutylammonium (TBA⁺), frequently applied for strongly retained anionic analytes.</p><p>These reagents are particularly useful when high retention strength is required.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_Table_1_Strong_Cationic_Ion_Pair_Reagents_8dbf00c57e.jpg" alt="KNAUER: Table 1 - Strong Cationic Ion-Pair Reagents." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_Table_1_Strong_Cationic_Ion_Pair_Reagents_8dbf00c57e.jpg 245w," sizes="100vw" width="1024" height="396"></p><h4><strong>Volatile (Weaker) Ion-Pair Reagents</strong></h4><p>Short-chain ion-pair reagents generate weaker retention but offer a significant advantage: compatibility with LC–MS detection.</p><p>Triethylammonium (TEA⁺) is among the most commonly used reagents for oligonucleotide analysis, particularly when mass spectrometric detection is involved. Other options, such as diisopropylethylammonium (DIEA⁺), are also widely applied, often combined with HFIP to enhance MS performance.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_Table_2_Weak_Cationic_Ion_Pair_Reagents_6332a4975e.jpg" alt="KNAUER: Table 2 - Weak Cationic Ion-Pair Reagents." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_Table_2_Weak_Cationic_Ion_Pair_Reagents_6332a4975e.jpg 245w," sizes="100vw" width="1024" height="283"></p><h4><strong>Building an IP-RP Method for Oligonucleotides</strong></h4><p>Developing a robust IP-RP method follows a logical sequence:</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_Table_3_IP_RP_Method_Step_Procedure_for_Oligos_c2216c24a0.jpg" alt="KNAUER: Table 3 - IP-RP Method Step Procedure for Oligos." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_Table_3_IP_RP_Method_Step_Procedure_for_Oligos_c2216c24a0.jpg 245w," sizes="100vw" width="1024" height="304"></p><h5><strong>1. Characterize the Analyte</strong></h5><p>Oligonucleotides typically contain 10–50+ nucleotides and exhibit high negative charge density. This necessitates a suitable cationic partner such as TEA⁺ or DIEA⁺.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_Figure_5_Cationic_Ion_Pair_Principle_for_Oligonucleotides_cb2dfb7457.jpg" alt="KNAUER: Figure 5 - Cationic Ion-Pair Principle for Oligonucleotides." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_Figure_5_Cationic_Ion_Pair_Principle_for_Oligonucleotides_cb2dfb7457.jpg 245w," sizes="100vw" width="512" height="320"></p><h5><strong>2. Select the Column</strong></h5><p>Use a reversed-phase column with:</p><ul><li>Large pore size (≈300 Å)</li><li>Appropriate internal diameter</li></ul><p>These parameters support the so-called “ON–OFF” retention mechanism — a bind-and-elute behavior where analytes are strongly retained until the gradient triggers rapid elution.</p><h5><strong>3. Optimize the Mobile Phase</strong></h5><p>A typical starting condition includes:</p><ul><li>10 mM TEA buffer at pH ~7</li><li>Acetonitrile as organic modifier</li></ul><p>Gradient programs from approximately 5% to 50% organic solvent over 15–30 minutes are commonly effective for complex oligonucleotide mixtures.</p><h5><strong>4. Adjust Retention Strength if Needed</strong></h5><p>To increase retention:</p><ul><li>Raise ion-pair concentration (up to ~100 mM if required)</li><li>Select a more hydrophobic ion-pair reagent</li></ul><h5><strong>5. Validate the Method</strong></h5><p>Ensure robustness, sensitivity, and reproducibility by carefully evaluating:</p><ul><li>UV chromatograms</li><li>MS traces</li><li>Peak shape and resolution</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_Figure_6_UV_MS_traces_of_IP_RP_Oligonucleotide_Analysis_81faf4e9f0.jpg" alt="KNAUER: Figure 6 - UV-MS traces of IP-RP Oligonucleotide Analysis." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_Figure_6_UV_MS_traces_of_IP_RP_Oligonucleotide_Analysis_81faf4e9f0.jpg 245w," sizes="100vw" width="1024" height="365"></p><h4><strong>Why IP-RP Is Considered the Gold Standard</strong></h4><p>Ion-Pair Reversed-Phase Chromatography uniquely combines the resolving power of reversed-phase LC with the ability to retain highly polar, charged biomolecules.</p><p>Its advantages include:</p><ul><li>Tunable selectivity</li><li>Compatibility with UV and MS detection</li><li>Scalability from analytical to preparative workflows</li><li>Applicability from research to pharmaceutical production</li></ul><p>By transforming highly charged oligonucleotides into hydrophobic ion-pair complexes, IP-RP enables precise and reproducible separations that would otherwise be impossible in conventional reversed-phase systems.</p><p>For these reasons, IP-RP is widely regarded as the benchmark technique for oligonucleotide analysis.</p><h4><strong>Final Thoughts</strong></h4><p>Mastering IP-RP is less intimidating than it may seem. A successful method comes down to:</p><ul><li>Selecting the right ion-pair reagent</li><li>Choosing a suitable column</li><li>Optimizing gradient conditions</li><li>Fine-tuning temperature and concentration parameters</li></ul><p>With thoughtful method development, IP-RP delivers sharp peaks, clean separations, and reliable performance — fully compatible with modern mass spectrometry workflows and ready to meet the demands of advanced oligonucleotide analysis.</p>

Oligos Made Easy - Part 3: IP-RP

News from LabRulezLCMS Library - Week 08, 2026

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Phenomenex is a global technology leader committed to developing novel analytical chemistry solutions that solve the separation and purification challenges of researchers in industrial, government and academic laboratories.

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Based in Berlin, KNAUER is a medium-sized, owner-managed company that has been serving the sciences since 1962. We develop and manufacture scientific instruments of superior quality for liquid chromatography, including: Analytical HPLC/UHPLC, Preparative HPLC, Fast protein liquid chromatography (FPLC), Multi-column chromatography/Simulated moving bed (SMB) chromatography. High pressure dosing, in-line detection systems, and osmometry are additional business areas.

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Thermo Scientific Ardia Platform

Built using cloud technology, the Ardia Platform centralizes information, including scientific data and results, maximizes instrument utilization, and accelerates data analysis to help scientists get closer to the truth.

<h3><strong>Bring your laboratory into a new era of connectivity with the Ardia Platform</strong></h3><p data-start="64" data-end="714"><strong>Digital transformation is a journey driven by the desire to fundamentally improve laboratory working practices by leveraging the latest advances in IT. The Thermo Scientific™ Ardia™ Platform allows the laboratory to harness the same technology.&nbsp;</strong></p><p data-start="64" data-end="714">In an era where laboratories are uncompromising in their pursuit of efficiency, the demand for software that seamlessly connects data, instruments, and scientists is on the rise.</p><p data-start="64" data-end="714">Built using cloud technology, the Ardia Platform centralizes information, including scientific data and results, maximizes instrument utilization, and accelerates data analysis to help scientists get closer to the truth.</p><figure class="image"><img style="aspect-ratio:1440/1127;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Ardia_Platform_2_4c83f21ef8.jpg" alt="Thermo Scientific Ardia Platform." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Ardia_Platform_2_4c83f21ef8.jpg 200w," sizes="100vw" width="1440" height="1127"></figure><h5><strong>Centralize</strong></h5><p>Revolutionize data management by bringing together all your data sources, formats, and applications into one platform. With centralized data, you gain unprecedented control, accessibility, and efficiency, enabling you to make data‑driven decisions with confidence.</p><h5><strong>Unify</strong></h5><p>Say goodbye to the complexities of managing data scattered across various systems and locations. The Ardia Platform integrates with a growing list of software tools and applications for direct data access and automated data transfer, allowing you to harness the power of a unified platform and help eliminate data silos.</p><h5><strong>Streamline</strong></h5><p>Eliminate time‑consuming manual data transfers with automated workflows via the Ardia Platform’s Data Sync tool. Automatically transfer data to and from your repository for applications that are not yet connected so users can focus on what matters most.</p><h5><strong>Collaborate</strong></h5><p>Collaboration goes beyond just centralizing data and integrating software. With a single platform, you can easily share, access, and collaborate on data. Real‑time data updates, shared dashboards, and collaborative tools facilitate efficient teamwork, accelerating project timelines and driving innovation</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Ardia_Platform_57590fecf7.jpg" alt="Thermo Scientific Ardia Platform." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Ardia_Platform_57590fecf7.jpg 245w," sizes="100vw" width="1022" height="450"></p><h3><strong>Data management</strong></h3><p>Securing, managing, and effectively utilizing large volumes of scientific data stored across multiple devices in different formats can be challenging and time-consuming.<br>The Ardia Platform offers robust data management capabilities that address these challenges. With automated central data storage, including backup and archival capabilities, and comprehensive access controls, users can securely access, view, and organize information from various applications more effectively.</p><blockquote><p><strong>webinar: </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/webinar/4962"><strong>Take control of your data and instruments</strong></a></p></blockquote><div><div data-message-author-role="assistant" data-message-id="ba34c04b-e6ae-4d15-ac9e-9e3606bb4933" dir="auto" data-message-model-slug="gpt-4o"><div><div><h4><strong>Centralize your data and enable accessibility and security</strong></h4><h5><strong>Manage</strong></h5><p data-start="64" data-end="990">The Ardia Platform provides secure, single‑point data management with automated transfer of data and results from <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/76"><strong>Thermo Scientific™ Chromeleon™ Chromatography Data System</strong></a><strong>, </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1758"><strong>Xcalibur™</strong></a><strong>,</strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1759"><strong> Compound Discoverer™</strong></a><strong>, </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1782"><strong>Proteome Discoverer™</strong></a><strong>,</strong> and<strong> </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1837"><strong>BioPharma Finder™ software</strong></a>, as well as third‑party application data via the Ardia Platform’s Data Sync functionality.<br>With single‑point data storage, users can enhance data accessibility, improve data organization and discovery, and reduce or eliminate data duplication.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Ardia_Platform_3_0ea16b74db.jpg" alt="Thermo Scientific Ardia Platform." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Ardia_Platform_3_0ea16b74db.jpg 245w," sizes="100vw" width="1440" height="544"></p><h5><strong>Secure</strong></h5><p data-start="64" data-end="990">Keep data secure and controlled with user login access, system‑generated audit trails, and embedded user and data management tools, customizable to your organization’s specific needs. Streamline your operations and ensure disaster resilience through built‑in capabilities, such as tracking actions and simplifying data backup and archiving.</p></div></div></div></div><h3><strong>Ardia Platform’s Data Viewer</strong></h3><p>The intuitive, web‑based Ardia Platform’s Data Viewer tool provides a <strong>single location</strong> for review of chromatography and mass spectrometry data, delivering consistency across software products integrated with the Ardia Platform.<br>With a new user interface, it’s easy to display chromatograms and spectra, quickly create extracted ion chromatograms, perform peak integration, export spectral data to the<strong> </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1764"><strong>mzCloud™</strong></a> library for easy compound annotation, and view diagnostic channels like pump pressure for troubleshooting.<br>Expedite data review with user‑friendly features that include the ability to import a mass list, export plots in .svg format for high‑resolution visualizations, and quickly display linked data‑dependent acquisitions.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Ardia_Platform_4_9d3c486827.jpg" alt="Thermo Scientific Ardia Platform." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Ardia_Platform_4_9d3c486827.jpg 245w," sizes="100vw" width="1918" height="1012"></p><h3><strong>Instrument management</strong></h3><p>Managing a set of individual instruments is often a manual, time-consuming task. Bringing them together in one place, the Ardia Platform’s Instrument application enables monitoring and management of all connected instruments to maximize utilization and eliminate paper records.<br>This can significantly improve productivity by minimizing downtime, reducing delays, and improving lab efficiency.</p><h4><strong>Effective instrument management to drive laboratory productivity</strong></h4><h5><strong>Monitor</strong></h5><p>Easily view all connected systems from a central location with instrument cards providing real‑time status and data acquisition information for a holistic laboratory view to enable fast, informed decisions.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Ardia_Platform_5_f985768d28.jpg" alt="Thermo Scientific Ardia Platform." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Ardia_Platform_5_f985768d28.jpg 245w," sizes="100vw" width="1692" height="809"></p><h5><strong>Record</strong></h5><p>Digitize, standardize, and centralize instrument logbooks with automated event logging, plus manual entry tools to record maintenance activities, custom notes, and images. Automatic tracking of instrument module movements between systems assists laboratories in maintaining accurate and complete records, helping to ensure instruments are controlled and working properly, instilling confidence in result reliability. Instrument support is accelerated via in‑app service ticket and support package generation for immediate delivery to Thermo Fisher Scientific technical support.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Ardia_Platform_6_1a2b159f68.jpg" alt="Thermo Scientific Ardia Platform." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Ardia_Platform_6_1a2b159f68.jpg 200w," sizes="100vw" width="873" height="680"></p><h5><strong>Schedule</strong></h5><p>Increase laboratory efficiency by optimizing instrument utilization. The Ardia Platform’s Instruments Scheduler tool provides a single point to plan work, view system availability, reserve time, and set maintenance windows on all connected instruments to minimize downtime.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Ardia_Platform_7_01ca77bc6d.jpg" alt="Thermo Scientific Ardia Platform." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Ardia_Platform_7_01ca77bc6d.jpg 245w," sizes="100vw" width="1483" height="548"></p><h5><strong>Utilize</strong></h5><p>The Ardia Platform’s Data Insights application provides out‑of‑the‑box dashboards for key laboratory insights on resource availability, instrument status, and instrument performance in a centralized location. Track and monitor system metrics such as injection quantity, time, volume, type or status, and % utilization across systems and geographical locations. With interactive dashboards that can be filtered by system, system type, location, project, or time, you can easily focus on the metrics that matter most.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Ardia_Platform_8_3a6b276497.jpg" alt="Thermo Scientific Ardia Platform." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Ardia_Platform_8_3a6b276497.jpg 245w," sizes="100vw" width="1920" height="937"></p>

Thermo Scientific™ BioPharma Finder™ Software for the Characterization of Biotherapeutics

Simplify comprehensive biotherapeutic attribute characterization with advanced capabilities to increase throughput and confidence in a connected environment.

<div><div container-id="cq-colctrl-lt7" comp-id="A1"><div><p><strong>Discover how the features of Thermo Scientific BioPharma Finder Software are engineered to support the world of complex biopharmaceutical characterization. Featuring novel data processing algorithms and easy-to-interpret data visualization tools, the software supports users looking to confidently characterize biopharmaceuticals.</strong></p><p>Power BioPharma Finder&nbsp;Software with the<a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1821"> <strong>Thermo Scientific Ardia Platform</strong></a> to automate file centralization during acquisition, expand file access, enable report creation and result sharing, and remove data management barriers from your daily routine.</p><div><h3><strong>Key benefits</strong></h3></div><div><ul><li><strong>Confident characterization: </strong>Explore a solution for confident animo acid sequence characterization with the <strong>Peptide Mapping Analysis</strong> module featuring a novel MS<sup>2</sup> prediction algorithm.</li><li><strong>Customized Nucleotide sequence support:</strong> Leverage the ability to create customized nucleotide sequences to support confirmation with the <strong>Oligonucleotide Analysis </strong>module featuring an improved MS<sup>2</sup> fragmentation model (available in BioPharma Finder Software version 5.3).</li><li><strong>Efficient data handling:</strong> Move through vast amounts of data with remarkable efficiency using the <strong>Intact Mass Analysis</strong> module. With innovative deconvolution algorithms and features, you can generate multi-consensus reports effortlessly, providing a comprehensive view of your results.</li><li><strong>Unparalleled Modification Exploration and Flexibility: </strong>The <strong>Top-Down Analysis</strong> module empowers you to search through an extensive range of modifications, even at the per-peak level. With multiple fragmentation modes and a cross-array processing algorithm, you have the flexibility to explore your samples in greater detail.</li><li><strong>Seamless integration: </strong>See how easy it is to move from sophisticated characterization using BioPharma Finder Software to confident quantitation in <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/76"><strong>Chromeleon CDS software</strong></a> with benefits added by the <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1821"><strong>Ardia Platform</strong></a> including connecting instrument data, supporting global access and centralizing BioPharma Finder reports.</li></ul><h3><strong>Learn more about BioPharma Finder Software</strong></h3><div><p>The<strong> right combination </strong>of data and software makes all the difference in accurately characterizing molecules, especially for large molecule.</p><h4><strong>Peptide mapping analysis</strong></h4><p>Characterization of a macromolecule comprised of an amino acid sequence can involve a lot of moving targets. Techniques for confident confirmation typically include comparisons of data collected against theoretical knowledge of the sequence. The best processing tools will also give users the ability to model probable sequences against the data collected with easy-to-use tools to increase the confidence of the identification and supply the summary reports with easy-to-interpret results.</p><div><h5><strong>Featured in the Peptide Mapping Analysis</strong></h5><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Bio_Pharma_Finder_Software_b88e243207.jpg" alt="Thermo Scientific™ BioPharma Finder™ Software: Processing with the novel MS2 algorithm in the Peptide Mapping Analysis module, generates a predictive model that includes Kinetical predictions that are compared with the measured spectra to increase confidence in the identification." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Bio_Pharma_Finder_Software_b88e243207.jpg 245w," sizes="100vw" width="1160" height="540"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Bio_Pharma_Finder_Software_2_6dda72b394.jpg" alt="Thermo Scientific™ BioPharma Finder™ Software:  These processing tools, when combined, produce intuitive result review tools including comprehensive coverage maps, deep dive spectral comparison views and graphical sample comparison options." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Bio_Pharma_Finder_Software_2_6dda72b394.jpg 245w," sizes="100vw" width="1160" height="600"></p><div><h5><strong>Detect and quantify host cell proteins</strong></h5></div><div><p>The sensitivity of the detection algorithm and prediction analytics allow for high confidence even for low abundance targets to support residuals applications like Host Cell Protein (HCP) analysis.</p></div><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Bio_Pharma_Finder_Software_3_e493898dc1.jpg" alt="Thermo Scientific™ BioPharma Finder™ Software: Detect and quantify host cell proteins." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Bio_Pharma_Finder_Software_3_e493898dc1.jpg 245w," sizes="100vw" width="1160" height="600"></p></div><h4><strong>Oligonucleotide analysis</strong></h4><div><p><strong>Sequence confirmation </strong>for oligonucleotides can be daunting. Take the question out of sequence confirmation with our enhanced MS<sup>2</sup> predictive algorithms that can iteratively create the best array of possibilities without iterating into infinity. Summarize your characterization with visual tools, generate easy-to-interpret results and enhance collaboration by saving and sharing reports in a connected environment.&nbsp;&nbsp;</p><h5><strong>Featured in the Oligonucleotide Analysis module</strong></h5><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Bio_Pharma_Finder_Software_4_f709ce5528.jpg" alt="Thermo Scientific™ BioPharma Finder™ Software:  The oligonucleotide sequence editor provides an easy-to-use interface for quickly and easily building and visualizing customized oligonucleotide sequences. Build out multiple expected sequences from custom building block subunits, a wide selection of modifications from the predefined list or with user-defined custom modifications." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Bio_Pharma_Finder_Software_4_f709ce5528.jpg 245w," sizes="100vw" width="1160" height="600"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Bio_Pharma_Finder_Software_5_f204e2cd40.jpg" alt="Thermo Scientific™ BioPharma Finder™ Software:  Eliminate alternative possibilities based on the entered sequence with the random sequence generator and leverage the in silico digest tools to support confident sequence verification - all using an updated MS2 prediction algorithm (available in BioPharma Finder Software version 5.3)." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Bio_Pharma_Finder_Software_5_f204e2cd40.jpg 245w," sizes="100vw" width="1160" height="600"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Bio_Pharma_Finder_Software_6_f7f2d9e029.jpg" alt="Thermo Scientific™ BioPharma Finder™ Software:  Perform mRNA mapping with selected in silico mRNA digestion or define the cleavage locations manually. Dig into the identity of fragments and expected or unexpected modifications and assess the overall coverage with intuitive visual coverage maps." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Bio_Pharma_Finder_Software_6_f7f2d9e029.jpg 245w," sizes="100vw" width="1160" height="600"></p></div><h4><strong>Intact mass analysis</strong></h4><div><div container-id="cq-colctrl-lt2" comp-id="B1"><div><p>Intact analysis on its face is a simple mathematical calculation used to deconvolute a series of m/z values into components but throw in the complexity of large molecule targets with modifications in a mixture of other like-molecules and mass accuracy becomes harder to achieve. No matter your data resolution,<strong> leverage innovative software tools engineered</strong> to filter and process through complex spectra with the <strong>Intact Analysis module.</strong> Discover how to quickly acquire and process batches of samples supported by a central data location on the <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1821"><strong>Ardia Platform</strong></a> and speed through large batch-to-batch comparison studies to create summaries with connected multi-consensus reports.</p><div><h5><strong>Featured in the Intact Analysis module</strong></h5><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Bio_Pharma_Finder_Software_7_72cfbd44c3.jpg" alt="Thermo Scientific™ BioPharma Finder™ Software:  Accurately determine molecular weights utilizing the Sliding Window algorithm coupled with our optimized Xtract (for high resolution) and Respect (for lower resolution) deconvolution algorithms. Achieve comprehensive detection, even for co-eluting, low-intensity components in complex mixtures and account for any shifts in retention time." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Bio_Pharma_Finder_Software_7_72cfbd44c3.jpg 245w," sizes="100vw" width="1160" height="323"></p></div><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Bio_Pharma_Finder_Software_8_d0c92fbca9.jpg" alt="Thermo Scientific™ BioPharma Finder™ Software:  Use the expanded sequence matching capabilities for oligonucleotides which includes the ability to perform Terminal Truncation Searching from either the 3' or 5' terminus, facilitating the identification of impurities with greater ease. " srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Bio_Pharma_Finder_Software_8_d0c92fbca9.jpg 245w," sizes="100vw" width="1160" height="600"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Bio_Pharma_Finder_Software_9_d345484402.jpg" alt="Thermo Scientific™ BioPharma Finder™ Software:  The intact mass analysis of heavily modified oligonucleotides presents analytical and data processing challenges due to the frequent usage of sulfur modifications. Pairing Thermo Scientific Orbitrap mass spectrometers with BioPharma Finder Software allows for confident intact mass identification of phosphorothioate conversion of oligonucleotides with less than 5 ppm error." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Bio_Pharma_Finder_Software_9_d345484402.jpg 245w," sizes="100vw" width="1160" height="600"></p></div></div></div><h4><strong>Top-down analysis</strong></h4><div><div container-id="cq-colctrl-lt2" comp-id="B1"><div><p><strong>Higher order structure characterization</strong> requires a combination of some of the most variable sample treatment techniques, variable data acquisition techniques, and combined or complex data processing techniques. Looking to gently pry apart large complexes without reducing them to their smallest parts and understand them is an art and a science that can be supported by the <strong>Top-Down Analysis module</strong>. Explore the tools offered to help refine the field of predicted possibilities without restricting them, the support for multi fragmentation mode data, and the easy-to-use multi-consensus summaries to understand your molecule.</p><div><h5><strong>Featured in the Top-Down Analysis module</strong></h5><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Bio_Pharma_Finder_Software_10_7e7ef85413.jpg" alt="Thermo Scientific™ BioPharma Finder™ Software:  With the ProSightBP processing tool users can set variable or static sites for modification, select peak specific deconvolution parameters and even select peak specific sequence searching then let ProSightBP create the predictions. Combine the data from multi fragmentation modes including CID, HCD, ETD, EThcD, and UVPD resulting in confident identification." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Bio_Pharma_Finder_Software_10_7e7ef85413.jpg 245w," sizes="100vw" width="1160" height="600"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Bio_Pharma_Finder_Software_11_e3c9f5084b.jpg" alt="Thermo Scientific™ BioPharma Finder™ Software:  Combining the predictive power of ProSight BP against the deconvoluted accurate mass with the sequence coverage from ETD and UVPD fragmentation reveals a comprehensive set of results to support confident molecule characterization." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Bio_Pharma_Finder_Software_11_e3c9f5084b.jpg 245w," sizes="100vw" width="1160" height="600"></p></div></div></div></div><h4><strong>Connecting to the Ardia Platform</strong></h4><div><p>Living in a world connected by networks that enable people to share everything doesn’t have to stop in the lab. With the<a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1821"><strong> Ardia Platform</strong></a> see how easy it can be to automatically centralize files, connect into those files from anywhere and process them with <strong>BioPharma Finder Software</strong> or any connected application.&nbsp;&nbsp;</p><div><h5><strong>Featured enhancements through connection</strong></h5><div><div container-id="cq-colctrl-lt2" comp-id="B1"><div><p><strong>Faster data review</strong></p><ul><li>Review a result generated by<strong> another colleague</strong> without having to import the results, open it from the shared secured Ardia Platform data repository, make comments or changes, and the software will automatically generate a new version to record the changes.</li></ul><p><strong>Better data management with centralized secured data</strong></p><ul><li>All results are <strong>securely </strong>saved in one place, no more finding the “right” computer or hard drive that contains the experiment and data.</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Bio_Pharma_Finder_Software_12_b6a814cd90.jpg" alt="Thermo Scientific™ BioPharma Finder™ Software:  Keep data secure and controlled. Gain insights into file history, method history, and manage user access with control." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Bio_Pharma_Finder_Software_12_b6a814cd90.jpg 245w," sizes="100vw" width="1160" height="600"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Bio_Pharma_Finder_Software_13_1e3b879f18.jpg" alt="Thermo Scientific™ BioPharma Finder™ Software:  Save and review individual reports without having to open BioPharma Finder Software for oligonucleotide, peptide mapping and intact mass applications. Utilize default reporting templates to speed development of customized reports and effectively modify templates to achieve desired result summary with the help of the customizable report designer." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Bio_Pharma_Finder_Software_13_1e3b879f18.jpg 245w," sizes="100vw" width="1160" height="600"></p><p>Enable collaboration on a global scale in a secure fashion to collaborate, compare, track, and finalize peptide results and workbooks using dynamic versioning history. Accelerate method optimization and review through a shared secure environment.</p></div></div></div></div></div></div></div></div></div></div>

Thermo Scientific SII for Empower Software

Incorporate and operate Thermo Scientific UHPLC, HPLC, GC, and IC instruments within other vendors' software platforms with the Thermo Scientific™ SII for Empower 3 Software plug-in.

<div id="product-description"><p><strong>Incorporate and operate Thermo Scientific UHPLC, HPLC, GC, and IC instruments within other vendors' software platforms with the Thermo Scientific™ Standard Instrument Integration (SII) for Empower 3 Software plug-in. The SII for Empower 3 plug-in is based on the </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/76"><strong>Thermo Scientific™ Chromeleon™ Chromatography Data System (CDS)</strong></a><strong> and offers unique and smart features that deliver maximum ease-of-use, reliability, and performance. It also enables Thermo Scientific™ chromatography systems to be operated and controlled by </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/627"><strong>Waters™ Empower™ 3 CDS software</strong></a><strong>.</strong></p></div><div><p>While <strong>Chromeleon CDS</strong> is the recommended software for control of <strong>Thermo Scientific UHPLC, HPLC, GC, and IC </strong>instruments due to its maximum ease of use, reliability, and performance, other vendors' CDS software can also incorporate and operate these instruments with the <strong>SII for Empower™ 3 Software</strong> plug-in.</p><p>The SII for Empower™ Software installs and uses portions of<strong> </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/76"><strong>Chromeleon CDS</strong></a>, such as the Services Manager, Instrument Configuration Manager, Instrument View, and Instrument Method Editor, to deliver flawless integration of Thermo Scientific LC, IC, and GC instrumentation into Empower™ 3 CDS without loss of functionality. Instrument control, data acquisition, and data processing are performed completely under Empower™ 3 Software.</p><p><strong>Configure your instruments</strong><br>Up to four instruments can be configured per Empower™ node using the standard Chromeleon Instrument Configuration Manager.</p><p><strong>Control your instruments</strong><br>SII for Empower™ Software provides a complete set of commands because they are present under native <strong>Chromeleon CDS </strong>control. For the user, this means that all the Chromeleon CDS tools and advanced features, such as preparing the next sample during an ongoing analysis, can be implemented to increase productivity and receive more data with fewer injections.</p><p><strong>SII for Empower™ controls the following systems:</strong></p><ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products?category=37&amp;manufacturerItems=3&amp;search=Vanquish"><strong>Thermo Scientific™ Vanquish™ HPLC and UHPLC systems</strong></a></li><li><strong>Thermo Scientific™ UltiMate™ 3000 HPLC systems</strong></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/410"><strong>Thermo Scientific™ Dionex™ ICS-6000 HPIC™ system</strong></a></li><li><strong>Thermo Scientific™ Dionex™ ICS-5000 HPIC™ system</strong></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/408"><strong>Thermo Scientific™ Dionex™ Integrion™ HPIC™ system</strong></a></li><li><strong>Thermo Scientific™ Dionex™ Aquion™ system</strong></li><li><strong>Thermo Scientific™ TRACE™ 1300 GC systems</strong></li></ul><p>Monitoring instrument status within Empower™ can be performed using the <strong>Empower™ Control Panel. </strong>Here, an enhanced SII Instrument View is easily accessed to provide further options to control and monitor the instrument and its modules.</p><p><strong>Instrument Methods</strong><br>Setting up an instrument method is simple, intuitive, and fast due to the <strong>SII for Empower™ Instrument Method Wizard and Editor</strong>, both of which are integrated into the Instrument <strong>Method Editor of Empower™</strong>. The wizard guides the user through all modules, enabling the entry of all necessary information, while the editor allows the review and modification of all aspects of a method.</p><p><strong>Process your data</strong><br>Complete data processing takes place inside<strong> Empower™ Software</strong>, which allows you to use all functionalities as you would normally, for example, overlay of chromatograms or other channels like pressure traces. The Empower™ user experience <strong>does not change </strong>for any data processing aspect.</p></div>

Thermo Scientific LC-MS Data Acquisition Software

Acquire the highest quality data possible to unlock the information, knowledge, and value in your samples with Thermo Scientific LC-MS Data Acquisition Software.

Thermo Scientific™ Chromeleon™ XPS Open Access Software

Thermo Scientific™ Chromeleon™ XPS provides streamlined and easy-to-use interface for Thermo Scientific™ Chromeleon™ CDS, while maintaining full capabilities of the CDS software.

<p><strong>In modern laboratories, chromatography techniques and the use of mass spectrometry (MS) detection are in high demand. Until recently, MS detectors were regarded as sophisticated detection tools that could be operated only by a highly trained specialist. Nowadays mass spectrometers are increasingly used as straightforward detectors for chromatography.</strong></p><p>Alongside this move into routine use of MS is the continued deskilling of staff in the laboratory world, causing highly experienced chromatographers to be in short supply. The result is a substantial number of regular scientists and process operators that need to generate chromatographic results using advanced instrumentation themselves.</p><p>The solution is an Open Access tool enabling users to simply walk up and use a very straightforward interface to exploit the full power of the chromatography data system (CDS), without actually using the CDS software itself. <strong>Thermo Scientific™ Chromeleon™ XPS </strong>provides this <strong>streamlined and easy-to-use</strong> interface for <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/76"><strong>Thermo Scientific™ Chromeleon™ CDS</strong></a>, while maintaining <strong>full capabilities</strong> of the CDS software, like instrument control, data processing, reporting and compliance tools.</p><h3><strong>Workflow</strong></h3><p>Users can walk up to <strong>any chromatography instrument</strong> connected to the CDS, with or without MS detection, and start to run their analysis with only a <strong>few mouse-clicks.</strong></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Chromeleon_XPS_Open_Access_Software_5e8f8c3dec.jpg" alt="Thermo Scientific™ Chromeleon™ XPS Open Access Software: First, select the analysis to perform (A) and which instrument should be used (B). The instrument overview shows the current instrument status’ and displays the estimated wait time until each instrument is available and the number of sample positions still available.  The instrument list is filtered depending on the analysis selected and the users privileges to only show appropriate instruments." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Chromeleon_XPS_Open_Access_Software_5e8f8c3dec.jpg 196w," sizes="100vw" width="876" height="697"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Chromeleon_XPS_Open_Access_Software_2_a8b64a52ae.jpg" alt="Thermo Scientific™ Chromeleon™ XPS Open Access Software: Next, enter the sample names (C) and any other parameters (D) required for the analysis." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Chromeleon_XPS_Open_Access_Software_2_a8b64a52ae.jpg 196w," sizes="100vw" width="876" height="697"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Chromeleon_XPS_Open_Access_Software_3_4b4367ffae.jpg" alt="Thermo Scientific™ Chromeleon™ XPS Open Access Software: Place the sample vials in the indicated positions and select Submit." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Chromeleon_XPS_Open_Access_Software_3_4b4367ffae.jpg 196w," sizes="100vw" width="876" height="697"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Chromeleon_XPS_Open_Access_Software_4_0386d31c9a.jpg" alt="Thermo Scientific™ Chromeleon™ XPS Open Access Software: The sequence is submitted and will run. The operator is shown the expected start and finish time of the analyses." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Chromeleon_XPS_Open_Access_Software_4_0386d31c9a.jpg 245w," sizes="100vw" width="625" height="263"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Chromeleon_XPS_Open_Access_Software_5_1b51ab8dd2.jpg" alt="Thermo Scientific™ Chromeleon™ XPS Open Access Software: At the end of the run, the results are automatically printed and/or exported and a link to the exported report can be distributed via email." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Chromeleon_XPS_Open_Access_Software_5_1b51ab8dd2.jpg 245w," sizes="100vw" width="814" height="309"></p><h3><strong>Configuration and management</strong></h3><p>Running samples is as easy as described above once Chromeleon XPS software is set up, configured and managed by an experienced chromatographer.</p><ul><li>All the methods required for the analysis must be created; the instrument method with all instrument control and data acquisition parameters, the processing method with all data processing parameters and the report template with all required results, to be reported.&nbsp;</li><li>A Chromeleon eWorkflow is created using these methods. An eWorkflow is an electronic procedure that automates all steps of the laboratory process related to a chromatographic analysis</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Chromeleon_XPS_Open_Access_Software_6_a3b2219e42.jpg" alt="Thermo Scientific™ Chromeleon™ XPS Open Access Software: The lab manager can customize Chromeleon XPS to show or hide individual toolbar buttons (A), which eWorkflows are visible to users (B) and which instruments they can access (C)." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Chromeleon_XPS_Open_Access_Software_6_a3b2219e42.jpg 196w," sizes="100vw" width="876" height="697"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Chromeleon_XPS_Open_Access_Software_7_d647111f5d.jpg" alt="Thermo Scientific™ Chromeleon™ XPS Open Access Software: In addition, it is possible to define various system options, such as which email notifications to send." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Chromeleon_XPS_Open_Access_Software_7_d647111f5d.jpg 193w," sizes="100vw" width="659" height="533"></p><p>Chromeleon XPS Open Access software lets <strong>any user</strong> run samples on their own by delivering a <strong>clean, streamlined walk-up interface</strong> that utilizes the<strong> full power</strong> of Chromeleon CDS. Users can access<strong> all instruments controlled by </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/76"><strong>Chromeleon CDS</strong></a><strong>, including MS</strong>, and automatically receive results or notifications about run completion or failure. The management console contains advanced customization options to fulfill any organization’s requirements, included fully regulated environments.</p><p><strong>Chromeleon XPS software provides error-free execution of any chromatography analysis with minimal training requirements for users.</strong></p>

Thermo Scientific Vanquish Tandem LC Systems

The Thermo Scientific Vanquish Tandem LC Systems increase throughput and maximize detector output by using a second pump and intelligent column switching to eliminate the time required for column equilibration in a gradient elution. 

<h3><strong>Optimize your productivity</strong></h3><p><strong>In today’s challenging research and production environments, you are being asked to be more productive without increasing spending or compromising quality.&nbsp;</strong></p><p>At the same time, <strong>advancements and innovations</strong> are needed to improve <strong>operational efficiency</strong> and <strong>performance</strong>. How do you accomplish this? It’s easy with the <strong>Thermo Scientific™ Vanquish™ High-throughput LC systems</strong> built for <strong>enhanced productivity</strong>. <strong>Vanquish High-throughput LC systems</strong> combine <strong>individual Vanquish components</strong> and <strong>software wizards</strong> to deliver <strong>increased throughput</strong> or <strong>detector utilization</strong>.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Vanquish_Duo_UHPLC_Systems_8_2befa2ab8e.jpg" alt="Thermo Scientific Vanquish Tandem LC Systems." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Vanquish_Duo_UHPLC_Systems_8_2befa2ab8e.jpg 191w," sizes="100vw" width="1325" height="1086"></p><h3><strong>Two flow paths for maximized productivity</strong></h3><p>Your laboratory may be facing <strong>increased pressure to improve working efficiency</strong> and deal with <strong>limiting resources</strong>, such as <strong>budget</strong>, <strong>space</strong>, or <strong>manpower</strong>. <strong>Vanquish High-throughput LC systems</strong> are designed to <strong>overcome these limitations</strong> by providing <strong>multiple flow paths</strong> for <strong>parallelization of specific stages of the LC run</strong>.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Vanquish_Duo_UHPLC_Systems_2_06370d93f8.jpg" alt="Thermo Scientific Vanquish Tandem LC Systems." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Vanquish_Duo_UHPLC_Systems_2_06370d93f8.jpg 245w," sizes="100vw" width="955" height="591"></p><h4><strong>Unique dual technology</strong></h4><p>The <strong>Vanquish platform</strong> contains <strong>two unique dual modules</strong>. <strong>Vanquish dual pumps</strong> merge <strong>two individual, low pressure mixing pumps</strong> in one housing enabling <strong>separate eluents and gradients</strong> for each pump.</p><p><strong>Vanquish dual split samplers</strong> possess <strong>two independently controlled injection units</strong> including <strong>separate injection valves and injection needles</strong>. Used in <strong>Dual LC and LC-MS workflows only</strong>, this enables <strong>high throughput</strong> and <strong>extensive sample characterization workflows</strong>.</p><h3><strong>Two configurations to best serve your needs</strong></h3><p><strong>Vanquish High-throughput workflows</strong> are configured with <strong>Thermo Scientific™ Vanquish™ Core system</strong>, <strong>Thermo Scientific™ Vanquish™ Flex system</strong> or <strong>Thermo Scientific™ Vanquish™ Horizon system</strong> modules. Both workflows make use of <strong>two pumps</strong> to <strong>increase instrument productivity</strong>.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Vanquish_Duo_UHPLC_Systems_3_77acff4bea.jpg" alt="Thermo Scientific Vanquish Tandem LC Systems: Two configurations to best serve your needs." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Vanquish_Duo_UHPLC_Systems_3_77acff4bea.jpg 245w," sizes="100vw" width="1682" height="735"></p><h4><strong>Vanquish Duo UHPLC Systems</strong></h4><ul><li><strong>Supported systems:</strong><ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/744">Vanquish Horizon</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/743">Vanquish Flex</a></li></ul></li><li><strong>Sampler:</strong> Dual split sampler</li><li><strong>Detector:</strong> Two out of the complete detector portfolio</li><li><strong>Software control:</strong><ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/76">Thermo Scientific™ Chromeleon™ Chromatography Data System (CDS)</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1838">Thermo Scientific™ Standard Instrument Integration (SII)</a> for <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/627">Waters™ Empower™ 3 CDS</a></li></ul></li></ul><h4><strong>Vanquish Tandem LC Systems</strong></h4><ul><li><strong>Supported systems:</strong><ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/744">Vanquish Horizon</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/743">Vanquish Flex</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/397">Vanquish Core</a></li></ul></li><li><strong>Sampler:</strong> Split sampler</li><li><strong>Detector:</strong> One out of the complete detector portfolio and/or one mass spectrometer</li><li><strong>Software control:</strong><ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/76">Chromeleon CDS</a></li><li>Standard System Integration for <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1758">Thermo Scientific™ Xcalibur™ software</a></li></ul></li></ul><h3><strong>Vanquish Tandem LC systems</strong></h3><div><div><div><div><p><strong>Gradient separations</strong> are commonly used in <strong>LC or LC-MS</strong>. <strong>Column reconditioning</strong>, such as <strong>washing and re-equilibration</strong>, takes time and <strong>reduces your overall sample throughput</strong>. The <strong>Vanquish Tandem LC systems</strong> eliminate these limitations and <strong>improve productivity</strong> by:</p><ul><li><strong>Increasing sample throughput</strong> without modifying a <strong>validated method</strong></li><li><strong>Improving return on investment</strong> by <strong>maximizing mass spectrometer utilization</strong></li><li><strong>Reducing column carry over</strong> through <strong>extended column washing</strong> without <strong>sacrificing throughput</strong></li><li><strong>Simplifying method setup</strong> with <strong>automatic method conversion</strong> from your original <strong>gradient method</strong></li></ul></div></div></div></div><div>&nbsp;</div><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Vanquish_Tandem_LC_Systems_4_a031ad3221.jpg" alt="Thermo Scientific Vanquish Tandem LC Systems." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Vanquish_Tandem_LC_Systems_4_a031ad3221.jpg 245w," sizes="100vw" width="1749" height="530"></p><h4><strong>Throughput increase using Tandem LC</strong></h4><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Vanquish_Tandem_LC_Systems_3_6bc55942ed.jpg" alt="Thermo Scientific Vanquish Tandem LC Systems: Throughput increase by Tandem LC is between 10–80% for most common conditions." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Vanquish_Tandem_LC_Systems_3_6bc55942ed.jpg 245w," sizes="100vw" width="894" height="434"></p><p>The <strong>Vanquish Tandem LC system</strong> splits the analysis between <strong>two pumps</strong> and <strong>two columns</strong>. One pump delivers the <strong>analytical gradient</strong> while the second pump runs the <strong>reconditioning gradient</strong>. This configuration allows you to use <strong>two identical columns</strong> to <strong>run your sequence faster</strong> without <strong>compromising data quality</strong>.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Vanquish_Tandem_LC_Systems_5_d818007fe4.jpg" alt="Thermo Scientific Vanquish Tandem LC Systems: Reproducible results for the Thermo Scientific™ Vanquish™ Horizon Tandem UHPLC system—Thermo Scientific™ Q Exactive™ HF hybrid quadrupole-Orbitrap™ mass spectrometer showing an overlay of five total ion current chromatograms. The sample shown is digested Infliximab using the Thermo Scientific™ SMART ™ Digest Kit." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Vanquish_Tandem_LC_Systems_5_d818007fe4.jpg 245w," sizes="100vw" width="1123" height="499"></p><h4><strong>Simply upgrade your method</strong></h4><p>Implementing <strong>Tandem LC-MS</strong> into your workflow is easy with <strong>compliance-ready Chromeleon software</strong> for LC or LC-MS users and <strong>Thermo Scientific Standard Instrument Integration (SII)</strong> for <strong>Thermo Scientific Xcalibur software</strong> for LC-MS users.</p><p>A <strong>simple dedicated instrument method wizard</strong> enables you to <strong>create new methods without the need for additional training</strong>.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Vanquish_Tandem_LC_Systems_0c7f310b1e.jpg" alt="Thermo Scientific Vanquish Tandem LC Systems." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Vanquish_Tandem_LC_Systems_0c7f310b1e.jpg 193w," sizes="100vw" width="353" height="285"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Vanquish_Tandem_LC_Systems_2_47128950b2.jpg" alt="Thermo Scientific Vanquish Tandem LC Systems: Chromeleon CDS and SII for Xcalibur guides users through the implementation of a Tandem LC or LC-MS method with automatic system volume considerations and gradient formation of the reconditioning pump." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Vanquish_Tandem_LC_Systems_2_47128950b2.jpg 160w," sizes="100vw" width="361" height="353"></p><h3><strong>Thermo Scientific LC portfolio overview</strong></h3><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_LC_portfolio_overview_2db5044366.jpg" alt="Thermo Scientific LC portfolio overview." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_LC_portfolio_overview_2db5044366.jpg 188w," sizes="100vw" width="795" height="660"></p>

Thermo Scientific Orbitrap Excedion Pro Mass Spectrometers

Welcome to the future of mass spectrometry. Enhance your research and achieve groundbreaking discoveries with Thermo Scientific Orbitrap Excedion Pro Hybrid Mass Spectrometers, the next generation of mass spectrometry.

Thermo Scientific Hypersil GOLD C8 HPLC Columns

For analytes with medium hydrophobicity or when a less hydrophobic phase is required to obtain optimum retention, use Thermo Scientific™ Hypersil GOLD™ C8 LC columns

<p><strong>For analytes with medium hydrophobicity or when a less hydrophobic phase is required to obtain optimum retention, use Thermo Scientific™ Hypersil GOLD™ C8 LC columns for outstanding sensitivity and excellent peak shape. The selectivity is similar to C18 columns with a predictable elution order but less retention. The lower hydrophobicity allows compounds to elute more quickly, yielding faster separations.</strong></p><h5><strong>Similar selectivity, less retention than C18 columns</strong></h5><ul><li>Successful retention and separation of moderately hydrophobic analytes</li><li>Ideal for fatty acids, which are too hydrophobic for analysis using C18 columns</li></ul><h5><strong>Faster separations</strong></h5><ul><li>Higher analytical throughput compared to C18 alkyl chain chemistry</li><li>Quicker compound elution due to reduced hydrophobic interactions</li></ul><h5><strong>Superior performance</strong></h5><ul><li>Highly symmetrical peak shapes</li><li>Improved speed of analysis, efficiency, and sensitivity</li></ul><h4><strong>Specifications</strong></h4><ul><li><strong>Endcapped:</strong> Yes</li><li><strong>Max. Pressure: </strong>5800 psi (400 bar)</li><li><strong>Packing Material:</strong> Spherical, Fully Porous, Ultrapure Silica</li><li><strong>Stationary Phase:</strong> C8</li><li><strong>Surface Area:</strong> 220 m²/g</li><li><strong>Temperature:</strong> 60°C</li><li><strong>USP Type: </strong>L7</li><li><strong>Carbon Load</strong>: 8%</li><li><strong>Phase:</strong> Reversed Phase</li><li><strong>Pore Size: </strong>175 Å</li><li><strong>pH: </strong>2 to 9</li></ul><h4><strong>About the Hypersil GOLD Family of HPLC Columns</strong></h4><p>Meet the challenges of modern chromatography with state-of-the-art columns that provide outstanding performance and consistent separations. <strong>Twelve different column chemistries</strong> are available so you can optimize separations and maximize productivity. Get outstanding peak shapes in reversed phase, ion exchange, HILIC, or normal phase chromatography.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Hypersil_GOLD_Columns_41d5984b62.jpg" alt="Thermo Fisher Scientific: Hypersil GOLD Columns" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Hypersil_GOLD_Columns_41d5984b62.jpg 150w," sizes="100vw" width="747" height="775"></p><ul><li><strong>Excellent peak symmetry</strong><ul><li>Hypersil GOLD columns <strong>produce highly symmetrical peaks</strong>, which facilitate the detection of low-level impurities that elute immediately after the main component. When there is even minor tailing, small impurity peaks can elute on the shoulder of the main peak, complicating the integration process.</li></ul></li><li><strong>Narrow peaks </strong>for outstanding efficiency</li><li><strong>Enhanced sensitivity</strong> and improved resolution</li><li><strong>Exceptional reproducibility </strong>for reliable chromatography, column after column</li><li>Solutions for <strong>high-throughput screening</strong></li><li><strong>1.9, 3, and 5 μm particle sizes </strong>for all your separation needs</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Hypersil_GOLD_Peak_symmetry_641b946673.jpg" alt="Thermo Fisher Scientific: Hypersil GOLD Columns: Peak symmetry" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Hypersil_GOLD_Peak_symmetry_641b946673.jpg 149w," sizes="100vw" width="880" height="925"></p>

Thermo Scientific Hypersil GOLD C4 HPLC Columns

For very hydrophobic analytes, achieve faster separations with excellent peak shapes using Thermo Scientific™ Hypersil GOLD™ C4 HPLC columns. 

<p><strong>For very hydrophobic analytes, achieve faster separations with excellent peak shapes using Thermo Scientific™ Hypersil GOLD™ C4 HPLC columns. Featuring a lower hydrophobicity than C18 or C8 columns, Hypersil GOLD C4 columns provide outstanding sensitivity and high efficiency.</strong></p><h5><strong>Similar selectivity, less retention than C18 or C8 columns</strong></h5><ul><li>Successful retention and separation of very hydrophobic analytes with this short alkyl chain length, low hydrophobicity column</li><li>Ideal for analysis of hydrophobic polypeptides and proteins</li></ul><h5><strong>Superior performance</strong></h5><ul><li>Highly symmetrical peak shapes</li><li>1.9 μm particle size columns improve speed and efficiency</li></ul><h4><strong>Specifications</strong></h4><ul><li><strong>Endcapped:</strong> Yes</li><li><strong>Max. Pressure: </strong>18130 psi (1250 bar)</li><li><strong>Packing Material:</strong> Spherical, Fully Porous, Ultrapure Silica</li><li><strong>Stationary Phase:</strong> C4</li><li><strong>Surface Area:</strong> 220 m²/g</li><li><strong>Temperature:</strong> 60°C</li><li><strong>USP Type: </strong>L26</li><li><strong>Carbon Load</strong>: 5%</li><li><strong>Phase:</strong> Reversed Phase</li><li><strong>Pore Size: </strong>175 Å</li><li><strong>pH: </strong>2 to 8</li></ul><h4><strong>About the Hypersil GOLD Family of HPLC Columns</strong></h4><p>Meet the challenges of modern chromatography with state-of-the-art columns that provide outstanding performance and consistent separations. <strong>Twelve different column chemistries</strong> are available so you can optimize separations and maximize productivity. Get outstanding peak shapes in reversed phase, ion exchange, HILIC, or normal phase chromatography.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Hypersil_GOLD_Columns_41d5984b62.jpg" alt="Thermo Fisher Scientific: Hypersil GOLD Columns" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Hypersil_GOLD_Columns_41d5984b62.jpg 150w," sizes="100vw" width="747" height="775"></p><ul><li><strong>Excellent peak symmetry</strong><ul><li>Hypersil GOLD columns <strong>produce highly symmetrical peaks</strong>, which facilitate the detection of low-level impurities that elute immediately after the main component. When there is even minor tailing, small impurity peaks can elute on the shoulder of the main peak, complicating the integration process.</li></ul></li><li><strong>Narrow peaks </strong>for outstanding efficiency</li><li><strong>Enhanced sensitivity</strong> and improved resolution</li><li><strong>Exceptional reproducibility </strong>for reliable chromatography, column after column</li><li>Solutions for <strong>high-throughput screening</strong></li><li><strong>1.9, 3, and 5 μm particle sizes </strong>for all your separation needs</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Hypersil_GOLD_Peak_symmetry_641b946673.jpg" alt="Thermo Fisher Scientific: Hypersil GOLD Columns: Peak symmetry" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Hypersil_GOLD_Peak_symmetry_641b946673.jpg 149w," sizes="100vw" width="880" height="925"></p>

Thermo Scientific Hypersil GOLD Phenyl HPLC Columns

Get excellent retention and unique selectivity for aromatic and moderately polar analytes with Thermo Scientific™ Hypersil GOLD™ Phenyl reversed phase HPLC columns

<p><strong>Get excellent retention and unique selectivity for aromatic and moderately polar analytes with Thermo Scientific™ Hypersil GOLD™ Phenyl reversed phase HPLC columns.&nbsp;</strong></p><p>A butyl (C4) linker in the phenyl bonded phase allows for superior alignment of the phenyl ring with aromatic molecules, thus enhancing pi-pi interactions and improving the retention of the molecules. The C4 linker also provides the stationary phase with moderate hydrophobicity, making it ideal for the separation of analyte mixtures with varying polarity and aromaticity. The outstanding peak shape results in greater sensitivity.</p><h5><strong>Special selectivity</strong></h5><ul><li>Provides selectivity complementary to that provided by alkyl chain phases</li><li>Moderate hydrophobicity compared to C18</li></ul><h4><strong>Specifications</strong></h4><ul><li><strong>Endcapped:</strong> Yes</li><li><strong>Max. Pressure: </strong>5800 psi (400 bar)</li><li><strong>Packing Material:</strong> Silica</li><li><strong>Stationary Phase:</strong> Phenyl/C4</li><li><strong>Surface Area:</strong> 220 m²/g</li><li><strong>Temperature:</strong> 60°C</li><li><strong>USP Type: </strong>L11</li><li><strong>Carbon Load</strong>: 9%</li><li><strong>Phase:</strong> Reversed Phase</li><li><strong>Pore Size: </strong>175 Å</li><li><strong>pH: </strong>2 to 8</li></ul><h4><strong>About the Hypersil GOLD Family of HPLC Columns</strong></h4><p>Meet the challenges of modern chromatography with state-of-the-art columns that provide outstanding performance and consistent separations. <strong>Twelve different column chemistries</strong> are available so you can optimize separations and maximize productivity. Get outstanding peak shapes in reversed phase, ion exchange, HILIC, or normal phase chromatography.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Hypersil_GOLD_Columns_41d5984b62.jpg" alt="Thermo Fisher Scientific: Hypersil GOLD Columns" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Hypersil_GOLD_Columns_41d5984b62.jpg 150w," sizes="100vw" width="747" height="775"></p><ul><li><strong>Excellent peak symmetry</strong><ul><li>Hypersil GOLD columns <strong>produce highly symmetrical peaks</strong>, which facilitate the detection of low-level impurities that elute immediately after the main component. When there is even minor tailing, small impurity peaks can elute on the shoulder of the main peak, complicating the integration process.</li></ul></li><li><strong>Narrow peaks </strong>for outstanding efficiency</li><li><strong>Enhanced sensitivity</strong> and improved resolution</li><li><strong>Exceptional reproducibility </strong>for reliable chromatography, column after column</li><li>Solutions for <strong>high-throughput screening</strong></li><li><strong>1.9, 3, and 5 μm particle sizes </strong>for all your separation needs</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Hypersil_GOLD_Peak_symmetry_641b946673.jpg" alt="Thermo Fisher Scientific: Hypersil GOLD Columns: Peak symmetry" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Hypersil_GOLD_Peak_symmetry_641b946673.jpg 149w," sizes="100vw" width="880" height="925"></p>

Products from Thermo Fisher Scientific - page 14

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