If you have been following my <a target="_blank" rel="noopener noreferrer" href="https://concentratingonchromatography.com/">Concentrating on Chromatography podcast</a>, you know that I am constantly searching for the cutting edge of separation science. After years of interviewing the brightest minds in the field, it has become clear to me that the <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/companies/218">Multidimensional Chromatography Workshop (MDCW)</a> is undeniably the best up-and-coming event in our industry.While I was unfortunately traveling in Asia during the most recent session, I was able to catch every detail thanks to the incredible work of <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/companies/1">LabRulez</a>. A huge thank you to Ivo Novotný and the LabRulez team for providing <a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/playlist?list=PLg-M6fM-05MrGrDggkl_UKzzcHPWPmssh">Open Access video presentations</a> of the event. Their <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/">portal </a>is an invaluable resource for anyone who needs to find technical information quickly and efficiently.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Organomation_MDCW_The_Premier_Up_and_Coming_Event_in_Chromatography_2_65b378bf01.jpg" alt="Organomation: MDCW: The Premier Up-and-Coming Event in Chromatography" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Organomation_MDCW_The_Premier_Up_and_Coming_Event_in_Chromatography_2_65b378bf01.jpg 245w," sizes="100vw" width="1044" height="455"><h3>The Minds Behind the Magic</h3>I have had the privilege of featuring the core organizers of MDCW on my podcast, including <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/articles?search=Katelynn+Perrault+Uptmor">Katelynn Perrault Uptmor</a>, <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/articles?search=Dwight+Stoll">Dwight Stoll</a>, and <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/articles?search=Petr+Vozka">Petr Vozka</a>. Their dedication to creating a space where forensic chemistry, environmental analysis, and metabolomics intersect is what makes this workshop so unique. The event is a perfect showcase for how multidimensional techniques—like GC×GC and 2D-LC—are essential for tackling the world's most complex samples.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Organomation_MDCW_The_Premier_Up_and_Coming_Event_in_Chromatography_265c9ec21e.jpg" alt="Organomation: MDCW: The Premier Up-and-Coming Event in Chromatography" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Organomation_MDCW_The_Premier_Up_and_Coming_Event_in_Chromatography_265c9ec21e.jpg 245w," sizes="100vw" width="792" height="230"><h3>Where Sample Prep Meets High-Resolution Analysis</h3>As we often discuss at Organomation, even the most advanced chromatographic systems depend on meticulous sample preparation. Two presentations highlighted in the LabRulez playlist perfectly illustrate the critical role of <a target="_blank" rel="noopener noreferrer" href="https://www.organomation.com/what-is-solvent-evaporation">solvent evaporation</a> and <a target="_blank" rel="noopener noreferrer" href="https://www.organomation.com/what-is-sample-concentration">sample concentration</a>.<h3>Chemical Fingerprints: Emma Macturk’s Quest for Hidden Data</h3><a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/watch?v=1W5197sp6IY">Emma Macturk</a>, working in Dr. Katelynn Perrault Uptmor’s lab, is redefining how we look at one of the oldest forms of forensic evidence: the fingerprint. While traditional forensics relies on the physical patterns of ridges and whorls, these are often incomplete or smudged in real-world scenarios. Emma’s research shifts the focus to the chemical residue left behind, which can provide vital "class characteristics" like the biological sex and relative age of a suspect.Her optimized workflow is a masterclass in handling complex biological matrices. Using a cotton swab to extract residue from surfaces, the samples are centrifuged and then "<a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/article/5392">blown down</a>" (a critical concentration step for any trace analysis) before <a target="_blank" rel="noopener noreferrer" href="https://www.organomation.com/what-is-reconstitution">being reconstituted for GC×GC-TOFMS</a>.What makes her work truly fascinating—and highly relevant for our readers at Organomation—is the discovery of anthropogenic compounds. Emma identified UVB blockers like octocrylene and various moisturizers hidden within the natural sterols and fatty acids of the skin. The power of multidimensional chromatography allows forensic scientists to resolve these external "lifestyle" markers from endogenous skin compounds, potentially providing a much more detailed profile of a suspect than a physical print ever could.<h3>The "Green" Revolution: Grace Saunders and the Future of Ballistics</h3><a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/watch?v=ClD4fjZMNtA">Grace Saunders</a> addressed a looming crisis in forensic ballistics: the shift toward "green ammunition." For decades, the gold standard for detecting gunshot residue (GSR) has been SEM-EDS, which looks for heavy metals like lead, barium, and antimony. However, modern environmental and health standards are leading manufacturers to omit these metals. This means that traditional standards are failing to identify GSR in cases involving green rounds.Grace’s research proposes a dual-pronged approach, using GC×GC to target Organic Gunshot Residue (OGSR). Her liquid extraction protocol is meticulous: samples are extracted in methanol, "<a target="_blank" rel="noopener noreferrer" href="https://www.organomation.com/what-is-evaporation-to-dryness">evaporated to dryness under nitrogen</a>," and then reconstituted. This ensures that volatile and semi-volatile nitroaromatic compounds, such as nitroglycerin and diphenylamine, are concentrated enough for detection.By optimizing parameters like the modulation period (2.5 seconds) and switching to hydrogen carrier gas, Grace was able to resolve these critical markers from the complex background "noise" of human skin. Her work isn't just about better chemistry; it’s about legal survival. As she noted, forensic methods must meet Federal Rule 702 for admissibility in court. Without the organic profiling Grace is developing, evidence from a "green" firearm discharge might never make it past a judge.<h3>The Future of Chromatography</h3>The workshop also featured brilliant presenters like <a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/watch?v=YJm_JwHbArE">Ryland Giebelhaus</a>, whose work on the metabolomics of cannabis exposure during pregnancy shows the real-world impact of these technologies.The MDCW isn't just another conference; it is a community-driven powerhouse that bridges the gap between proof-of-concept and field-ready applications. Whether you are looking for advanced data reduction strategies or the latest in high-resolution mass spectrometry, this is the event to watch.<blockquote>If you missed it this year like I did, I highly recommend visiting the <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?search=MDCW">LabRulez portal</a> to see the full breadth of research presented!</blockquote>

MDCW: The Premier Up-and-Coming Event in Chromatography

🎤Alex BrodyIn this episode of Concentrating on Chromatography, we sit down with Alex Brody, an organic chemist at Aqua America, to discuss the rigorous analytical methods required for regulated drinking water testing.Alex walks us through the multi-step PFAS detection process using EPA Method 537.1, including extraction, nitrogen blowdown concentration, and LC-MS analysis. He explains why sample preparation and quality control are critical for achieving trace-level detection—and why these methods can't be rushed or simplified, even with new technologies available.We also explore taste and odor investigations, disinfection byproducts, and volatile organic compounds, plus the surprising reality of why regulated labs move slowly when adopting new instrumentation. You'll learn about the quality control checkpoints, peer review processes, and the misconceptions surrounding analytical turnaround times in compliance labs.<h5>Topics Covered:</h5><ul><li>Role of organic chemistry in regulated drinking water labs</li><li>EPA compliance requirements and regulatory bodies (EPA, PA-DEP)</li><li>PFAS detection using Method 537.1 and LC-MS</li><li>The critical importance of nitrogen blowdown sample concentration</li><li>Taste and odor analysis: MIB, Geosmin, and unknown compound identification</li><li>Why regulated methods evolve slowly (validation timelines, approval processes)</li><li>Quality control procedures: calibration checks, matrix spikes, surrogate standards, internal standards</li><li>Automated sample preparation and lab efficiency</li><li>Future PFAS regulations and Method 533 expansion</li></ul><h5>Ideal For:</h5><ul><li>Analytical chemists and environmental lab professionals</li><li>Water utilities and compliance officers</li><li>Chromatography practitioners interested in regulated workflows</li><li>Anyone curious about how drinking water safety is ensured</li></ul><h2>Video Transcription</h2><h3>Ensuring Safe Drinking Water Through Advanced Analytical Chemistry</h3><h4>Insights from a Regulated Water Testing Laboratory</h4>Analytical laboratories responsible for regulated drinking water testing operate under strict compliance frameworks to ensure the delivery of safe and reliable water supplies. In this interview, Alex, an organic chemist at Aqua America, outlines the scope of analytical work conducted in a modern water quality laboratory. The team primarily focuses on the determination of taste- and odor-causing compounds, disinfection byproducts, volatile organic compounds (VOCs), and per- and polyfluoroalkyl substances (PFAS). These analyses rely heavily on GC-MS and LC-MS instrumentation, supported by rigorous maintenance programs to ensure continuous operational performance and data reliability.<h4>Regulatory Compliance and Quality Control in Drinking Water Analysis</h4>Operating as a regulated drinking water laboratory requires adherence to stringent requirements established by agencies such as the U.S. Environmental Protection Agency (EPA) and state-level regulatory bodies. Compliance is driven by extensive quality control protocols integrated into every analytical batch. Typical workflows include calibration verification, matrix spike recovery assessments, internal standard monitoring, and surrogate performance checks. Notably, analytical batches are often limited in sample number to accommodate a substantial proportion of quality control samples, reflecting the critical importance of data defensibility in regulatory reporting.One common misconception is the perceived speed at which results can be delivered. In reality, comprehensive sample preparation, including extraction procedures and validation steps, can extend turnaround times to a full working day or longer. Additionally, validated regulatory workflows impose limitations on the rapid adoption of new analytical technologies, as method modifications must undergo formal evaluation and approval before implementation.<h4>Analytical Strategies for Taste and Odor Investigations</h4>Taste and odor events represent a significant operational challenge for water utilities. Standard targeted methods are routinely applied for compounds such as 2-methylisoborneol (MIB) and geosmin, which are commonly associated with earthy or musty sensory characteristics. When targeted analysis does not reveal the source, laboratories employ broad-scan GC-MS screening combined with spectral library interpretation to identify potential causative compounds. In some cases, sensory evaluation panels complement instrumental analysis, providing preliminary insight into potential treatment-related or environmental influences affecting water quality.<h4>PFAS Monitoring: Methodological Complexity and Trace-Level Sensitivity</h4>PFAS determination represents a rapidly evolving priority in drinking water monitoring. The laboratory currently applies EPA Method 537.1, with efforts underway to expand capabilities through certification for Method 533, thereby broadening analyte coverage. Analytical workflows typically involve solid-phase extraction followed by solvent evaporation using nitrogen-assisted blow-down techniques to achieve the trace-level sensitivity required for regulatory compliance. This concentration step is essential because PFAS compounds remain non-volatile under controlled evaporation conditions, enabling enhanced detection performance upon reconstitution and LC-MS analysis.<h4>Future Directions in Drinking Water Analytics</h4>Looking ahead, the primary technological driver in regulated water analysis is the demand for increasingly lower detection limits and expanded compound coverage. While regulatory frameworks can slow methodological innovation, laboratories continue to pursue efficiency improvements, such as automated sample preparation systems and optimized analytical workflows. These advances support the growing need to process high sample volumes while maintaining the stringent data quality standards required for public health protection.Ultimately, the work performed in regulated drinking water laboratories represents a critical intersection of analytical chemistry, environmental monitoring, and public safety. Continuous methodological refinement, coupled with advances in mass spectrometry and sample preparation technologies, will play a central role in addressing emerging contaminants and ensuring long-term water quality assurance.<blockquote>This text has been automatically transcribed from a video presentation using AI technology. It may contain inaccuracies and is not guaranteed to be 100% correct.</blockquote><blockquote><h4>Concentrating on Chromatography Podcast</h4>Dive into the frontiers of chromatography, mass spectrometry, and sample preparation with host David Oliva. Each episode features candid conversations with leading researchers, industry innovators, and passionate scientists who are shaping the future of analytical chemistry. From decoding PFAS detection challenges to exploring the latest in AI-assisted liquid chromatography, this show uncovers practical workflows, sustainability breakthroughs, and the real-world impact of separation science. Whether you’re a chromatographer, lab professional, or researcher you'll discover inspiring content!You can find Concentrating on Chromatography Podcast in podcast apps:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://open.spotify.com/show/1wZg67rCjoGju4yhqxI3tL">Spotify</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podcasts.apple.com/tz/podcast/concentrating-on-chromatography/id1788429185">Apple podcast</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podscan.fm/podcasts/concentrating-on-chromatography">podscan</a></li></ul>and on <a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/@ChromatographyTalk/videos">YouTube channel</a></blockquote>

Regulated Drinking Water Testing: PFAS Detection, Sample Prep & Real Lab Insights

Anna Vanluchene&nbsp;from UCT Prague’s&nbsp;Department of Chemical Engineering has received a&nbsp;prestigious start-up grant from the Dagmar Procházková Fund. However, she did not receive funding right away. In this interview, she describes how she developed ten versions of her&nbsp;Illuminating Flow&nbsp;project idea (combining photocatalysis with flow reactors for pharmaceutical synthesis). She explains why she considers perseverance to be crucial when applying for grants, how international experience has influenced her approach to team management, and how her research can reduce the chemical industry’s&nbsp;dependence on fossil fuels and imports from China.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/VSCHT_Praha_Na_startovaci_grant_jsem_cekala_dva_roky_a_napsala_deset_verzi_projektu_2_5b7d63b8e9.jpg" alt="VŠCHT Prague/Tomáš Balický: I waited two years for a start-up grant and wrote ten versions of my project idea" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_VSCHT_Praha_Na_startovaci_grant_jsem_cekala_dva_roky_a_napsala_deset_verzi_projektu_2_5b7d63b8e9.jpg 127w," sizes="100vw" width="1128" height="1387"><h5>What did the Dagmar Procházková Fund grant mean to you?</h5>I&nbsp;consider it to be a&nbsp;great success. It is the first injection of funding that will allow me to ensure full independence for my research endeavour, to start my own research group, and to fund students so I&nbsp;can get started properly.<h5>What have been your previous experiences with grants?</h5>During my doctorate, a cotutelle (international doctorate under dual supervision), I&nbsp;was funded by a&nbsp;grant from the French government. Then I&nbsp;worked at the Academy of Sciences of the Czech Republic (CAS) and received a&nbsp;Marie Skłodowska-Curie Action (MSCA) Postdoctoral Fellowship to go abroad. The idea for my now-funded project was developed about two years ago and, since then, I&nbsp;have gradually developed and adapted the idea for various grant calls. I&nbsp;submitted about ten different versions of the proposal. I&nbsp;did not receive a&nbsp;grant from the Dagmar Procházková Fund last year, but this year, my application was successful.<h5>This probably requires a&nbsp;great deal of patience and perseverance.</h5>Certainly, because the success rates for most grants have been declining for some time. But as a&nbsp;motivational example, I&nbsp;will tell the story of Timothy Noel, a&nbsp;Belgian professor of chemistry living in the Netherlands. He applied for the prestigious European Research Council (ERC) grant, which is among the most sought-after in Europe, seven times. But no failure deterred him and eventually he succeeded and opened the door to potentially massive grant funding. He was already one of the world’s&nbsp;top scientists in the field at that time and openly described his journey on his blog <a target="_blank" rel="noopener noreferrer" href="https://www.noelresearchgroup.com/2022/03/17/my-personal-story-to-obtain-an-erc-grant-7-submissions-4-interviews-and-6-heartbreaks/">blog</a>.<h5>What advice does this convey to other grant applicants and early career researchers?</h5>Start early, read a&nbsp;lot, don’t&nbsp;give up, and—most importantly—apply repeatedly. Learn from rejections and overcome possible frustration from failures. Read blogs and books by successful people, where you will find not only the glorious results of their work, but also the hardships they faced over their entire journeys. Of course, building your team and laboratory is impossible without finances. I&nbsp;myself still hope that I&nbsp;will be able to receive even bigger grants in the future.<h5>How has your international experience influenced your scientific approach?</h5>A&nbsp;lot and on several levels. Different laboratories teach you how to do&nbsp;things differently. You gain varied experience about how different institutions function. You see other people’s&nbsp;positive motivations, their ability to be ambitious without negativity, their involvement in institutional matters, their openness to cooperation with companies (e.g., tech transfers, spin-offs). The most important thing is to broaden your horizons. I&nbsp;see going abroad as a&nbsp;necessity. What I&nbsp;have taken away the most is drive, great support, and the idea that scientific output is not just about metrics, but also about dedication to one’s&nbsp;topic.<h5>What is your Illuminating Flow: Transport Phenomena in Photocatalysis about, in layperson’s&nbsp;terms, and how is it unique?</h5>Most of today’s&nbsp;chemical industry is still based on thermal processes and fossil fuels. Photochemistry enables electrification, where the energy source is photons delivered by LEDs, which can generate electricity from renewable sources. Current research focuses mainly on chemical reactions and their mechanisms, but as a&nbsp;chemical engineer, I&nbsp;focus on designing processes and reactors suitable for industrial use. In batch reactors, light fades rapidly with distance from a&nbsp;source, so much of a&nbsp;reaction mixture is not illuminated. Flow reactors solve this problem, but they bring new challenges such as working with solid catalysts and subsequently scaling up production and achieving higher production rates of the desired chemicals at a&nbsp;given scale.One can imagine a&nbsp;transparent tube with a&nbsp;catalyst on the walls, upon which light shines and through which reactants flow. This project has a&nbsp;unique emphasis on engineering solutions and overall process efficiency.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/VSCHT_Praha_Na_startovaci_grant_jsem_cekala_dva_roky_a_napsala_deset_verzi_projektu_3_b978abf25c.jpg" alt="VŠCHT Prague/Tomáš Balický: I waited two years for a start-up grant and wrote ten versions of my project idea" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_VSCHT_Praha_Na_startovaci_grant_jsem_cekala_dva_roky_a_napsala_deset_verzi_projektu_3_b978abf25c.jpg 241w," sizes="100vw" width="1228" height="799"><h5>So, were you inspired by a&nbsp;gap in the market to connect photocatalysis with transport phenomena?</h5>Exactly. I&nbsp;combine my areas of expertise: microfluidics, photocatalytic degradation of organic substances (CAS), and synthesis (MSCA Postdoctoral Fellowship). The idea itself is not new, and pharmaceutical companies are very interested in “greener” photochemistry, but in practice, there is often a&nbsp;lack of appropriate engineering solutions and apparatus for industrial use.<h5>What are the practical applications of your work and what substances are you focusing on?</h5>Mainly on pharmaceuticals and on the synthesis of so-called fine chemicals, which are often the building blocks for the production of pharmaceuticals. There is also a&nbsp;geopolitical dimension to this, i.e. less dependence on imports from China and sustainable synthesis in Europe where it makes economic sense.<h5>And what chemicals are you specifically talking about?</h5>For example, building blocks for advanced synthesis, compounds prepared by trifluoromethylation reactions, or products of oxidation reactions with singlet oxygen. At the same time, we focus on reactions that are, in the classical design process, less safe or technologically demanding, where new approaches, such as photochemistry in flow reactors, could be safer and have better process control. Of course, this is not a&nbsp;universal solution for all types of reactions.<h5>The goal of this project?</h5>I&nbsp;plan to start a&nbsp;fully functional laboratory and research team, create high-quality experimental data on selected molecules and based on them, try to build cooperation with industrial partners. Without data, it is impossible to come to companies with just an idea. Within three years, I&nbsp;would like to have results that can be realistically presented and further developed.<h5>What are the main challenges in transport phenomena during photocatalysis?</h5>The methodology for repeatability of experiments in photochemistry is relatively demanding and there are unforeseen obstacles in building apparatus. Also, the scale-up from microliters to a&nbsp;larger scale.<h5>What methodology will you use, and how big are the microreactors and their flow rates?</h5>I&nbsp;have two different directions in methodological design. The first direction involves microreactors the size of a&nbsp;laboratory slide. You make a&nbsp;structure using a&nbsp;laser, and then you have to cast it and make a&nbsp;microreactor. This allows you to quickly adjust the geometry of the reactor. This method is, of course, not applicable in the commercial setting, but it is ideal for studying transport phenomena and precise measurements.The second direction involves reactors that are flow cells. These are already larger, approximately 15 x 15 centimetres, and their flow rates are in the order of millilitres per hour. This is the initial scale that we will further increase during the project.<h5>There is a&nbsp;big difference between a&nbsp;flow rate of microlitres per hour and industrial needs. Will it not work differently in reality?</h5>Our research will focus on studying the phenomena themselves for now, and scaling will be addressed later. In addition, we will combine the experimental data obtained with computer simulations that will help design suitable conditions for a&nbsp;larger scale. For some high-value fine chemicals, these scales, combined with continuous operation or parallelization of reactors, may already be practically usable.<h5>What catalysts will you use and how will you attach them to the reactor walls?</h5>I&nbsp;am focusing on heterogeneous photocatalysis, and we will mainly use graphitic carbon nitride and its more advanced modifications. These are semiconductor materials that can be synthesized relatively easily and are suitable for immobilization on glass reactor walls. A&nbsp;key part of this project is the creation of a&nbsp;stable catalytic layer for long-term flow-through operations. To increase the contact of reactants with the catalyst, we will also consider multiphase modes, for example, gas bubbling, in order to disrupt the otherwise laminar flow.<h5>Why did you choose this field and the Department of Chemical Engineering?</h5>During my postdoc in Belgium, the department had an opening for an Assistant Professor position that caught my attention and I&nbsp;applied for it. I&nbsp;did my undergraduate, graduate, and initial doctoral studies here, and I&nbsp;love the department. I&nbsp;have a&nbsp;Bachelor’s&nbsp;degree in Chemistry.<h5>Are you collaborating with anyone?</h5>We collaborate with BUT Brno focusing on creating layers and immobilizing catalysts on glass, as well as with the Institute of Chemical Process Fundamentals of the Academy of Sciences of the Czech Republic. And as for organic synthesis, we are connected with Ghent University via postdoc internships. At the same time, my colleague Viola Tokárová and I&nbsp;received a&nbsp;Czech Science Foundation grant in cooperation with BUT Brno and Masaryk University, with our part of the project focusing on the use of flow reactors for photochemical reactions and testing the antibacterial properties of photocatalytic materials. And I&nbsp;am writing other grant proposals in which I&nbsp;am trying to build new collaborations.<h5>What does the creation of an independent research group at UCT Prague look like?</h5>I&nbsp;started by renovating the premises that were assigned to me and gradually building my team. It is important for research work to have Ph.D. students; I&nbsp;have already hired one and we will recruit more. In addition to building the group, I&nbsp;will engage in securing further funding for the group, so I&nbsp;will be writing more grant proposals. It is important to think far enough in advance when it comes to prospective funding for a&nbsp;research group.<h5>What type of students are you looking for?</h5>The laboratory and team I&nbsp;are building will be very multidisciplinary, just like the area I&nbsp;am working on. That is why I&nbsp;am looking for students who are attracted to true multidisciplinary research, those who, for example, have knowledge of engineering, but who don’t&nbsp;mind a&nbsp;little bit of pure chemistry. One student in their own right does not have to (and cannot) know every subject, so I&nbsp;will ideally have a&nbsp;team consisting of different people with different research backgrounds. Motivated, DIY-type students who would rather enthusiastically build or invent something themselves than conduct repetitive measurements. Organic or analytical chemists will also find their place here. If this topic is interesting to students in any way, they can definitely contact me. I&nbsp;am also open to interdepartmental cooperation with other UCT Prague Faculties.<h5>How would you describe your path to photocatalysis/chemical engineering?</h5>Studying Chemistry as an undergrad gave me a&nbsp;broad perspective, but I&nbsp;was gradually narrowing my focus and eventually chose engineering. Chemical engineering intrigued me with its logic and was the easiest for me to grasp at the time. But I&nbsp;have always enjoyed working on projects more than the studies themselves. Even during my Bachelor studies, I&nbsp;really enjoyed and was interested in the Professor Štěpánek Group’s&nbsp;projects, where I&nbsp;was doing something completely different than I&nbsp;do&nbsp;now. I&nbsp;only got into photochemistry during my time at CAS and then, during my postdoctoral fellowship, I&nbsp;devoted myself to electrochemistry. My current focus is, thus, a&nbsp;natural interlinking of all these areas. Consequentially, I&nbsp;developed an awareness of the necessity to become independent and return to the department with my own, different research agenda, which, in my opinion, is an important and correct basis for establishing my own research group.<h5>What is the biggest challenge of this project for you?</h5>The transition from being a&nbsp;postdoc to a&nbsp;leadership position is a&nbsp;big change for me and I&nbsp;think it is not talked about enough. It means a&nbsp;shift from my own experimental work to leading a&nbsp;team, planning and delegating tasks, and motivating students. From a&nbsp;practical point of view, one of the main challenges is the transfer of reactions from the microscale to functional systems, the construction of reactors, the immobilization of catalysts, and generally confirming that this direction makes sense in the long term and that it has future potential.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/VSCHT_Praha_Na_startovaci_grant_jsem_cekala_dva_roky_a_napsala_deset_verzi_projektu_1_66ac267e06.jpg" alt="VŠCHT Prague/Tomáš Balický: I waited two years for a start-up grant and wrote ten versions of my project idea" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_VSCHT_Praha_Na_startovaci_grant_jsem_cekala_dva_roky_a_napsala_deset_verzi_projektu_1_66ac267e06.jpg 155w," sizes="100vw" width="830" height="839">

I waited two years for a start-up grant and wrote ten versions of my project idea

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The University of Chemistry and Technology, Prague is a natural centre of first-rate study and research in the area of chemistry in Czechia and is one of the country's largest educational and research institutions focused on technical chemistry, chemical and biochemical technologies, material and chemical engineering, food chemistry, and environmental studies.

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Waters Corporation

<h4>Automating Laboratory Workflows with Andrew+ and OneLab Software: A Virtual Demonstration</h4>
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<h4>Other episodes rfom the series:</h4>
Transform Your Daily Lab Operations with Automation - Episode 1: Biomolecules workflows
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<li>Tuesday, June 11, 2024, 11:00 AM CEST</li>
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Transform Your Daily Lab Operations with Automation - Episode 2: Pharma workflows
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<li>Tuesday, July 09, 2024, 11:00 AM CEST</li>
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<blockquote>
Presenter: Jasper Eaton (Senior Product Marketing Manager, Waters Corporation)
</blockquote>
<blockquote>
Jasper has a Bachelor’s degree in General Biology and obtained a Masters Degree in Molecular and Cellular Biology from the University of Grenoble-Alpes. He was previously the EU Sales Manager at Andrew Alliance since 2017, and is now a Senior Product Marketing Manager at Waters Corporation. His experience has made him well versed in the challenges faced by customers looking to automate their lab workflows.
</blockquote>
<blockquote>
Presenter: Xavier Rodriguez (Principal Applications Specialist, Chemistry, Europe, Waters Corporation)
</blockquote>
<blockquote>
Xavier is part of the European Market Development Team. He works as an Application Specialist with focus on sample prep and has more than 20 years of experience in solving sample prep challenges.
</blockquote>

Waters Corporation: Transform Your Daily Lab Operations with Automation - Episode 3: Food and Environmental Workflows

Transform Your Daily Lab Operations with Automation - Episode 3: Food and Environmental Workflows

We’ll show how Andrew+ and OneLab use automation to streamline everything from drug discovery to quality control.

Automation with Andrew+: Food and Environmental Workflows

<h4>SCIEX OS software summer school</h4>
Master the essentials of SCIEX OS software with our live webinars this summer
Join us for our summer school series dedicated to enhancing your proficiency with SCIEX OS software. Over the course of next months, we offer a series of concise, 30-minute webinars designed to fit into your schedule.
Agenda:
<ul>
<li>23 July, 11:00 a.m. CET – Hardware configuration and instrument verification</li>
<li>6 Aug, 11:00 a.m. CET – Compound optimization</li>
<li>20 Aug, 11:00 a.m. CET – Data processing: quantitation</li>
<li>2 September, 11:00 a.m. CET – Data processing: screening</li>
</ul>

SCIEX OS software summer school - Data processing: quantitation

Join us for our summer school series dedicated to enhancing your proficiency with SCIEX OS software.

Data processing: quantitation

SCIEX OS software summer school - Data processing: screening

Data processing: screening

Delivering connected science for your lab evolution
In the fast-paced world of laboratory operations, staying ahead of regulatory changes, increasing demands, and fierce competition is essential. However, outdated instrumentation and software can often hinder your progress.
Our newly launched software is meticulously crafted to elevate laboratory efficiency and ensure reproducibility, all while minimising manual errors. One of the core tenets of our software is its user-friendly interface, designed with simplicity in mind. Here’s your opportunity to get firsthand experience!
<h3>AGENDA</h3>
<h5>09:00 Welcome + Coffee + Networking</h5>
<h5>09:30 Introduction to waters_connect: Delivering connected science for your lab evolution</h5>
<h5>09:45 Streamlining System Setup and Data Acquisition: Maximizing efficiency and accuracy</h5>
<h5>10:30 Coffee and networking opportunities</h5>
<h5>11:00 Compound optimization with just a few clicks - Hands-on workshop</h5>
<h5>11:45 Mastering MS Quan: Demonstration of next generation of data processing</h5>
<h5>12:30 Lunch</h5>
<h5>13:30 Mastering MS Quan: Unleash your analytical potential- hands-on workshop</h5>
<h5>15:30 General discussion, coffee and wrap-up</h5>

Waters Corporation: waters_connect for Quantitation workshop

waters_connect for Quantitation workshop

Here’s your opportunity to get firsthand experience.

Data management and manual transcription of critical process data remain one of the major challenges and potential sources of errors in the analytical laboratory.
As a lot of the laboratory processes evolve around sample preparation for HPLC or GC, with crucial weighing and preparative steps, this webinar aims to showcase some seamless data management and transfer solutions, from balance to LC. The LabX™ balance software and OpenLab CDS platform can enable various levels of integrated data management, while also improving productivity and offering a high degree of data integrity.
Join the METTLER TOLEDO and Agilent teams for a webinar to understand how you can support digitalized and scalable sample preparation processes for better chromatography results. 
Program Overview
<ul>
<li>Introduction to the digital lab
</li>
<li>Improving analytical sample preparation workflows
</li>
<li>Live demonstration of seamless data transfer options
</li>
<li>Q&amp;A with presenters
</li>
</ul>
<blockquote>
Presenter: Andrea Brütsch (Head Business Development Initiatives)
</blockquote>
<blockquote>
Presenter: Kevin Koelliker (Agilent Technologies, Application Engineer)
</blockquote>

Mettler Toledo: Automated Data Management for LC/GC Workflows

Automated Data Management for LC/GC Workflows

How can you support digitalized and scalable sample preparation processes for better chromatography results.

Join us for an exclusive two-day event where Agilent will showcase cutting-edge biopharma solutions.
The first day of the event we will explore Agilent’s comprehensive portfolio for the spectrum of applications from drug discovery to quality control. Learn more about our cell analysis and genomics expertise and the tools we provide to drive IVT mRNA development, protein therapeutics and cell and gene therapies
The second day will focus on advanced analytical solutions, including HRMS for tRNA sequencing and LC/MS for DNA/RNA analysis. Learn how to scale up oligonucleotide purification with Agilent biocolumns, which enhance the efficiency and accuracy of your processes.
By attending this event you will:
<ul>
<li>Gain insights from Agilent to optimize biotherapeutic workflows, including rigorous quality testing in cGMP environments and handling nucleic acid, vaccines, mAB and protein samples.
</li>
<li>Understand how metabolic analyses can impact CAR cell function and behavior, using cytolytic cell killing assays on the xCELLigence system to develop cell therapy processes and confirm product potency.
</li>
<li>Learn about new techniques in high-resolution LC/MS for analyzing tRNA modifications.
</li>
<li>Discover software tools available for high-resolution MS systems in both research and QA/QC labs.
</li>
<li>Compare analytical and semipreparative LC purification methods for synthetic oligonucleotides, gaining competitive insights into purification strategies.
</li>
</ul>
<h5>Talk 1: Advanced Analytical Solutions for Nucleic Acid Analysis and Purification</h5>
<ul>
<li>Presented by Dr. Charlotte Lekieffre, Biopharma Application Specialist, Agilent Technologies</li>
</ul>
The emphasis during the second day of the Summit will be on advanced analytical solutions, such as HRMS for tRNA sequencing and LC/MS for DNA/RNA analysis. Additionally, you’ll discover techniques to enhance the efficiency and accuracy of your processes by scaling up oligonucleotide purification using Agilent biocolumns. 
<h5>Talk 2: Extracted Yeast tRNA Sequencing by LC-MS/MS</h5>
<ul>
<li>Presented by Aurore Attina, Engineer of Mass Spectrometry, University of Montpellier</li>
</ul>
RNA modifications are essential for RNA stability, maturation, and functionality; directly influencing protein translation and gene regulation. They play a central role in various biological processes and are associated with many diseases, including cancers and neurological disorders. tRNA (transfer RNA), which plays a key role in protein synthesis, is the most modified molecule in the organism known to date. tRNA modifications are essential to ensure their correct function in protein translation, maintain the accuracy and fidelity of the genetic code, and enable flexible adaptation to changing cellular conditions and are therefore a crucial attribute to monitor. To monitor and map these modifications of tRNA, we have developed a LC-HRMS analytical workflow, first using synthetic oligonucleotide for the method optimization. In this webinar, we will first go through the various steps involved in LC-MS/MS method optimization using synthetic oligonucleotides. In a second part, we will present the protocol development of an enzymatic digestion applied to tRNA extracted from yeast. This digestion generates oligonucleotide fragments that can be analyzed by LC-MS/MS for sequence confirmation.
<h5>Talk 3: Discover Agilent’s Software Tools to Confirm Oligonucleotide Sequence Integrity</h5>
<ul>
<li>Presented by Dr. Holger Stalz, LC/MS Product Specialist Austria &amp; Switzerland, Agilent Technologies</li>
</ul>
Mass spectrometry (MS) is increasingly important for the development of therapeutic modalities such as oligonucleotides. A common analytical method for large molecules is intact mass by LC/MS. This can be used for the characterization and identification of a product or process-related impurities, or simply as a confirmation of molecular weight. The newly introduced Agilent OpenLab CDS 2.8 SW version comes with a set of features to enable the automatization of biopharma workflows. If you want to know how LC/MSD Spectral Deconvolution of your biopharma samples can be automated, we will provide answers during our presentation. Even more details on Oligonucleotide sequence confirmation and impurities characterization can be acquired using the power of a high-resolution accurate mass system (HRAM) on the Agilent 6545XT AdvanceBio LC/Q-TOF. Analyzing the sample data with the software workflows in Agilent BioConfirm version 12 will support the user to get the trusted answers to their most relevant questions.
<h5>Talk 4 Maximize Your Resources and Simplify Scale-up with AdvanceBio Oligonucleotide Columns</h5>
<ul>
<li>Presented by Dr. Andrea Tripodi, Application Development Engineer, Agilent Technologies</li>
</ul>
Several classes of nucleic acids, such as antisense oligonucleotides, small interfering RNAs (siRNAs), and aptamers are being investigated for potential therapeutic applications. Synthetic oligonucleotides inevitably contain many impurities due to limitations in the efficiency of each chemical reaction used during manufacture. They include deletion sequences (missing one or more nucleotides) and reaction by-products often arising during the final deprotection or cleavage steps. Ion pair reversed-phase (IP-RP) chromatography stands out as the prevalent method for analyzing and purifying oligonucleotides. For increased resolution and separation of your full-length synthetic oligonucleotide from closely related impurities, AdvanceBio Oligonucleotide is the ideal choice. The latest developments include semi-preparative, and lab-scale preparative columns packed with superficially porous particles that provide excellent performance and resolution without compromising column loading. A fast and easy scale-up method from analytical to semi-preparative scale was successfully achieved using a 10 mm ID column enabling higher sample loading using the same analytical LC instrument.

Technology Networks: Biopharma Innovations Summit

Biopharma Innovations Summit Day 2

Learn more about our cell analysis and genomics expertise and the tools we provide to drive IVT mRNA development.

We are excited to bring you a three-part Ask Me Anything webinar series on one of the topics you ask about most – processing data. Empower Software allows you to use two different peak detection algorithms, Traditional and ApexTrack. What are the differences between these algorithms and when might you use one versus the other? Given all the choices on the Integration tab of the Processing Method, how do you set these important parameters to ensure accurate peak integration? &nbsp;In the first part of this webinar series, we will explore the algorithms and learn how to set the parameters in a logical fashion. We will discuss:<ul><li>How both algorithms work</li><li>Starting with peak width and threshold first</li><li>Interactively setting timed events in the chromatogram</li><li>Practical examples</li><li>Empower System Policies that impact your peak detection and integration</li></ul>Please join us for a lively discussion as we explore this topic. As always, please bring your questions for this exclusive opportunity to ask our experts anything about Empower Software.<blockquote>Presenter: Neil Lander (Principal Product Manager, Informatics, Waters Corporation)Neil has worked for Waters Corporation since 1994 and has held a variety of positions including Technical Support Specialist, Technical Trainer, Manager Customer Education and currently, Principal Marketing Manager focusing on Informatics solutions. He provides internal support for Empower Chromatography Data System and is focused on developing laboratory software solutions that help organizations achieve their scientific and operational objectives. Prior to joining Waters, he was an analytical chemist where he gained experience in both the cosmetics and specialty chemical industries.</blockquote>

Waters Corporation: Empower Tips: Ask Me Anything About Processing Data - Part 1

Empower Tips: Ask Me Anything About Processing Data - Part 1

We will explore the algorithms and learn how to set the parameters in a logical fashion.

Empower Tips: Ask Me Anything About Processing Data

Day one: Innovation and data insights<ul><li>Discover how to achieve high sensitivity, speed, and resilience when working with large, complex sample sets</li><li>Learn strategies to speed up your covalent protein drug discovery</li><li>Gain insights into accelerating the development of multiple modalities</li><li>Understand the latest advancements in quantitative proteomics with ZT Scan DIA</li><li>Overcome limitations with cutting-edge artificial intelligence quantitation software</li></ul>Agenda-at-a-glanceWelcome and introduction to innovation and data insights&nbsp;&nbsp;&nbsp;&nbsp;Advancing robustness and serviceability of a high-end triple quad mass spectrometer in a high-throughput bioanalytical lab<ul><li>Highly sensitive mass spectrometers allow the advanced bioanalytical labs of today to achieve the LOQ required of potent biologic drugs and provide maximum flexibility in choice of sample prep techniques. However robust mass spectrometers are crucial for several reasons:<ul><li>Aid in ensuring the consistent quantitative performance of an assay</li><li>Effectively allow a lab to meet their project timelines</li><li>Are essential for handling the inherent variability of analyzing diverse molecules and diverse samples required for bioanalysis</li></ul></li></ul>The new fast in drug discovery: a new MS system to study covalent protein drugs<ul><li>The combination of a super-fast sampling interface with the highly sensitive ZenoTOF 7600 system makes it an ideal system for evaluating covalent binding screens. Main findings in our experiments using the Echo® MS+ system:<ul><li>Speed: measurements from a full 384-well plate in 15 min or 1536-well plate in less than one hour</li><li>Precision: low injection volume supports repetitive measurements and time series; capture full kinetic data set in one experiment</li><li>Quality: high data quality allows for full automated processing, delivering immediate hitlist output</li></ul></li></ul>icIEF-UV/MS characterization of charge Isoforms for biotherapeutic products<ul><li>Characterization of icIEF charge isoforms, whether in early product development or associated with licensure filings, is usually achieved through ion exchange (IEX) liquid chromatography coupled with mass spectrometry. icIEF-MS technology has recently emerged to enable the direct characterization of specific species in the icIEF electropherogram, eliminating the need for extensive method development.<ul><li>Discover opportunities to advance core platform technologies with novel characterization approaches</li><li>Hear case studies on understanding molecular structure information</li><li>New approaches to characterizing post-translational modifications of charge isoforms</li></ul></li></ul>Expanding qualitative and quantitative sensitivity for immunopeptidomics using ZT Scan DIA<ul><li>Learn how utilizing a research-grade Zeno-trap time-of-flight LC-MS system can advance current applications in immunopeptidomics and proteomics, including:<ul><li>What is ZT Scan DIA, the technology and how it benefits data acquisition</li><li>Preliminary proteomics and immunopeptidomics results using ZT Scan DIA</li><li>Future applications of immunopeptidomics using ZT Scan DIA</li></ul></li></ul>Artificial intelligence quantitation (AI quant): molecular structure and mass spectral data quality driven processing of high-resolution mass spectrometry for quantitative analysi<ul><li>High-resolution mass spectrometry (HRMS) has long sought to be a viable alternative for quantitative workflows but has been unable to broadly compete, mainly due to the lack of suitable data processing software. In this work we describe:<ul><li>A molecular structure-dependent workflow</li><li>The holistic and user-independent processesing of HRMS data</li><li>The automatic quantification of small drug-like molecules</li></ul></li></ul>Q&amp;A roundtable: innovation and data insights with the experts<ul><li>Moderated by: Jamie Wighton, Senior Director LC-MS Research, SCIEX</li><li>Panelists include:<ul><li>Rathna Veeramachaneni, Director, Biopharma LC-MS/MS, KCAS Bio</li><li>Xiaping He, Senior Scientist, Pfizer</li><li>Markus Stöckli, Senior Principal Scientist, Novartis Institutes for BioMedical Research</li><li>Tony Purcell, Professor, Monash University&nbsp;</li><li>Kevin Bateman, Retired Pharmacokinetics, Pharmacodynamics and Drug Metabolism Expert</li></ul></li></ul><blockquote>Moderator: Jamie Wighton (Senior Director LC-MS Research, SCIEX)Jamie joined SCIEX 20 years ago and has held multiple technical and leadership roles throughout his career at SCIEX. &nbsp;Starting out as an engineer in manufacturing operations, Jamie has since led teams in supply chain, product development, and most recently the research and product applications teams within R&amp;D. Prior to joining SCIEX, Jamie worked at JDS Uniphase as an optical test engineer.Jamie holds a B.Sc. in engineering physics from Queen’s University.Presenter: Rathna Veeramachaneni (Director, Biopharma LC-MS/MS, KCAS Bioanalytical)Presenter: Markus Stöckli, Senior Principal Scientist, Novartis Institutes for BioMedical ResearchPresenter: Xiaoping He, Senior Scientst, PfizerPresenter: Tony Purcell, Professor, Monash UniversityPresenter: Kevin Bateman, Retired Pharmacokinetics, Pharmacodynamics and Drug Metabolism Expert</blockquote>

SCIEX summit Day one: Innovation and data insights

Importance of LC-MS in food and environmental testing, pharmaceutical and biopharmaceutical discovery and development and biomedical and omics research.

Day two: Characterization and discovery<ul><li>Characterize and quantify calreticulin (CALR) arginylation using electron-activated top-down proteomics</li><li>Achieve in-depth profiling of metabolites and lipids in biological samples</li><li>Obtain accurate and reliable metabolite identification using electron-based fragmentation (EAD)</li><li>Detect trace amounts of pesticide residues in food by targeted and non-targeted, IDA and SWATH approaches</li><li>Enhance routine characterization of low-abundant sequence variant (SV) through fast and sensitive EAD-DDA</li></ul><h5>Agenda-at-a-glance</h5>Welcome and introduction to characterization and discoveryTop-down characterization of post-translational arginylation using electron activated dissociation (EAD)<ul><li>Learn about our top-down proteomics workflow for the characterization and quantification of calreticulin (CALR) arginylation. MS1 profile and MS2 fragmentation were characterized by EAD. Preferential fragmentation at the CALR N-terminals yielded sufficient c ions facilitating precise localization of the arginylation sites. Learn about:<ul><li>Arginylation regulates CALR degradation and ER function</li><li>EAD is efficient in characterizing N-terminal arginylation</li><li>The workflow sets up the foundation for unbiased top-down activity-based arginylation profiling</li></ul></li></ul>In-depth metabolomics and lipidomics analyses<ul><li>Routine measurement of metabolites and lipids has become a cornerstone of biomedical research. At the MPC, Helmholtz Munich, non-targeted analysis is based on the SCIEX ZenoTOF 7600 for accurate and in-depth analysis and annotation of metabolites and lipids from different biological specimens.<ul><li>Application of Zeno trap enabled non-targeted workflows to large scale metabolomics and lipidomics studies</li><li>Enhanced sensitivity enables deeper profiling of biological samples</li><li>Increased confidence in identifications through comprehensive structural elucidation using Electron activated dissociation (EAD)</li></ul></li></ul>MetID innovations in pharma: exploring new avenues for metabolite structure elucidationTime-of-flight mass spectrometry applications in food science: targeted and non-targeted approaches<ul><li>Time-of-flight mass spectrometry has become a key tool in analytical laboratories involved in food analyses. This instrumentation can be used for both targeted and non-targeted approaches. In this presentation, we will discuss:<ul><li>Overview of practical targeted and non-targeted approaches in food analysis</li><li>Application of a SWATH® approach to the analysis of pesticide residues in food</li><li>Application of IDA approaches in non-targeted food analyses</li></ul></li></ul>Reduce risk and accelerate cell line development with iCIEF-UV/MS technology<ul><li>Guide decisions during cell line development with the Intabio ZT system with more information on how process changes affect cell line and product stability. &nbsp;<ul><li>How to utilize icIEF-UV/MS to identify sequence variants</li><li>How this information can be used to create a mitigation strategy</li><li>What more information in less time means to groups throughout process development</li></ul></li></ul>Q&amp;A roundtable: A deeper look at high-resolution mass spectrometry<ul><li>Moderated by: ose Castro-Perez, Vice President of Product Management, SCIEX</li><li>Panelists include:<ul><li>Tom Lin, Instructor, Washington University in St. Louis</li><li>Michael Witting, Deputy Head Metabolomics and Proteomics Core and Executive Manager Metabolomics, Helmholtz Munich</li><li>Francisco José Díaz-Galiano, Postdoctoral researcher, University of Almería</li><li>Kirsten Nields, Principal Scientist, J&amp;J Innovative Medicines</li><li>Tatjana Talamantes, Senior Product Manager, Accurate Mass, SCIEX</li></ul></li></ul><blockquote>Moderator: Tatjana Talamantes, Senior Product Manager, Accurate Mass, SCIEXTatjana is a Senior Product Manager at SCIEX, overseeing accurate mass systems since 2021. She collaborates with R&amp;D, sales, and marketing teams to ensure effective project execution and portfolio management.Previously, Tatjana was a Product Manager at MOBILion Systems, leading the pre-commercialization of SLIM-based ion mobility instruments. She also has held roles at Thermo Fisher Scientific as a Sr. Vertical Marketing Specialist and Sr. Field Applications Scientist.Tatjana holds a B.A. in chemistry from Austin College and a Ph.D. in biomedical sciences and biochemistry from the University of North Texas Health Science Center.Jamie holds a B.Sc. in engineering physics from Queen’s University.Presenter: Tom Lin, Instructor, Washington University in St. LouisPresenter: Michael Witting, Deputy Head Metabolomics and Proteomics Core and Executive Manager Metabolomics, Helmholtz MunichPresenter: Francisco José Díaz-Galiano, Postdoctoral researcher, University of AlmeríaPresenter: Kirsten Nields, Principal Scientist, J&amp;J Innovative MedicinesPresenter: Tatjana Talamantes, Senior Product Manager, Accurate Mass, SCIEX</blockquote>

SCIEX summit Day two: Characterization and discovery

CIEX summit Day two: Characterization and discovery

Method development and validation is a time-consuming process that requires the attention of experienced laboratory personnel. There are tools that integrate with Empower Software that dramatically reduce the time needed to build methods, evaluate results, and validate the final method. With these tools you can free up experienced laboratory personnel to carry out other tasks. These tools are compatible with older versions of Empower Software if you have Windows 10.In this webinar we will discuss:<ul><li>Method Developer Application – A new autonomous tool for method screening</li><li>Sample Set Generator – A tool that automates the creation of Instrument Methods, Method Sets and Sample Set Methods for method development and validation</li><li>Method Validation Manager – An Empower Software option that automates chromatographic method validation and performs all necessary statistical calculations</li><li>Scoring Report – A Report Method that scores and ranks the results of method development experiments making it easy to select the optimum separation</li><li>Third-Party AQbD Software – Software that integrates seamlessly with Empower Software to define the experimental region within which changes to method parameters will not significantly affect the separation</li></ul>Please join us for a lively discussion as we explore this topic. As always, please bring your questions for this exclusive opportunity to ask our experts anything about Empower Software.<blockquote>Presenter: Neil Lander (Principal Product Manager, Informatics, Waters Corporation)Neil has worked for Waters Corporation since 1994 and has held a variety of positions including Technical Support Specialist, Technical Trainer, Manager Customer Education and currently, Principal Marketing Manager focusing on Informatics solutions. He provides internal support for Empower Chromatography Data System and is focused on developing laboratory software solutions that help organizations achieve their scientific and operational objectives. Prior to joining Waters, he was an analytical chemist where he gained experience in both the cosmetics and specialty chemical industries.</blockquote>

Waters Corporation: Empower Tips: Ask Me Anything About Tools for Method Screening, Development, and Validation

Empower Tips: Ask Me Anything About Tools for Method Screening, Development, and Validation

In this webinar we will discuss method Developer Application – A new autonomous tool for method screening, sample Set Generator etc.

LCMS webinars focusing on Software - page 20