Ask any analytical chemist which hyphenated technique has become indispensable over the past decade, and the answer will almost certainly be the same: tandem chromatography–mass spectrometry. Whether it is <a target="_blank" rel="noopener noreferrer" href="https://www.organomation.com/preparing-samples-for-lc-ms/ms-analysis">LC–MS/MS</a> quantifying a novel biologic’s metabolic fate, or <a target="_blank" rel="noopener noreferrer" href="https://www.organomation.com/preparing-samples-for-gc-ms/ms-analysis">GC–MS/MS</a> chasing per- and polyfluoroalkyl substances (PFAS) down to sub-part-per-trillion levels in municipal water, the combination of chromatographic separation with the specificity of tandem mass detection has become the analytical workhorse of choice across virtually every regulated sector.Below we examine the key forces propelling this expansion, from biopharma pipeline dynamics and PFAS regulatory mandates to AI-driven automation and reshoring of pharmaceutical manufacturing—and explore what each trend means for laboratories managing sample preparation and analytical workflows.<h3>Biopharma: The Engine Room of LC–MS/MS Demand</h3><h4>GLP-1 Agonists and the Metabolomics Gold Rush</h4>The explosive commercial and scientific interest in GLP-1 receptor agonists—<a target="_blank" rel="noopener noreferrer" href="https://www.sepscience.com/advancing-glp-1-peptide-analysis-chromatography-challenges-and-innovations-12163">semaglutide and related peptide therapeutics </a>for diabetes and obesity—has dramatically expanded the analytical demands placed on tandem MS platforms. Discovery programs require precise quantification of peptide drug candidates and endogenous biomarkers across complex biological matrices. These workflows rely on high-sensitivity LC–MS/MS for pharmacokinetic profiling, receptor occupancy studies, and metabolomics characterization. Metabolomics is, in fact, projected to be the fastest-growing application segment in mass spectrometry, driven in part by its growing role in cancer screening, biomarker discovery, and metabolic disease research.I have been spending more time learning about GLP-1s because this is the hot topic that people want to discuss on the Concentrating on <a target="_blank" rel="noopener noreferrer" href="https://open.spotify.com/show/1wZg67rCjoGju4yhqxI3tL?si=n9GLz9zjSCOrVfXPxFPhng&amp;nd=1&amp;dlsi=52868e027aad4d22">Chromatography podcast</a>. With that said, I was astounded looking at CNBC.com during breakfast this morning to see that <a target="_blank" rel="noopener noreferrer" href="https://www.cnbc.com/2026/03/21/glp-1-diets-restaurants-protein-fiber-weight-loss-drugs.html">one in eight Americans are currently taking one of these drugs such as Ozempic</a>.<h4>Antibody–Drug Conjugates and Gene Therapy: Complexity at Every Step</h4>The ascent of antibody–drug conjugates (ADCs) and gene therapies has introduced a new level of analytical complexity. ADCs blend the target specificity of monoclonal antibodies with the cytotoxic potency of small-molecule payloads—and characterizing the linker chemistry, drug-to-antibody ratio (DAR), and conjugate stability demands high-resolution LC–MS/MS at every stage from discovery through QC release testing. Gene therapy vectors require equally rigorous characterization of impurities, aggregates, and empty/full capsid ratios.This translates into a direct need for low-evaporation, high-recovery concentration methods that preserve labile protein structures and maintain sample integrity prior to LC–MS/MS injection. <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/article/5392">Nitrogen evaporation workflows</a> that minimize oxidative stress and maintain sample temperature are increasingly critical in these pipelines.<h4>Precision Medicine and Multi-Omics Integration</h4>The shift toward precision medicine has accelerated adoption of high-throughput, multi-analyte MS platforms. Proteomics, metabolomics, and lipidomics workflows are converging on a single analytical platform—tandem MS—and generating datasets of a scale and complexity that were unimaginable ten years ago.Make no mistake: the triple quadrupole serves an irreplaceable role in quantitative targeted analysis. At the same time, <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products?category=134&amp;manufacturerItems=3">Orbitrap </a>and Q–TOF hybrid platforms are growing rapidly as researchers demand full-scan accurate mass for untargeted discovery.<h3>Environmental Mandates: PFAS Testing Drives Adoption</h3>Environmental testing is something that every person, chemist or not, can understand the importance of. Mounting mandates from the U.S. Environmental Protection Agency and European regulators regarding PFAS—the “forever chemicals” whose extraordinary environmental persistence is matched only by the analytical challenge of detecting them at trace levels—have created immediate, compliance-driven investment in LC–MS/MS infrastructure.<h4>The Regulatory Framework Chemists Need to Know</h4>The EPA has codified a suite of LC–MS/MS-based methods as the analytical standard for PFAS in water and solid matrices:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://blog.organomation.com/blog/epa-533-drying-down-pfas-samples-after-spe">EPA Method 533</a>: Weak anion exchange SPE combined with LC–MS/MS; covers 25 PFAS including short-chain compounds in drinking water.</li><li><a target="_blank" rel="noopener noreferrer" href="https://blog.organomation.com/blog/sample-concentration-epa-method-537-pfas-determination">EPA Method 537.1</a>: Reversed-phase SPE followed by LC–MS/MS; covers 18 PFAS including the GenX compound, with method detection limits in the low ng/L range.</li><li><a target="_blank" rel="noopener noreferrer" href="https://www.agilent.com/en/solutions/environmental/water-testing/pfas-in-water/us-epa-method-8327?srsltid=AfmBOooCY1pcavj7B1PH-75d3HO4BGDglNlhmyTyrpDY3zvUksMO1dlg">EPA Method 8327</a>: LC–MS/MS for selected PFAS in prepared extracts of aqueous and solid matrices.</li><li><a target="_blank" rel="noopener noreferrer" href="https://blog.organomation.com/blog/preparing-diverse-sample-matrices-for-epa-method-1633">EPA Draft Method 1633</a>: The emerging benchmark for PFAS in non-aqueous matrices—aqueous, solid, biosolids, and tissue—quantifying up to 40 PFAS.</li></ul>All of these methods designate LC–MS/MS, specifically LC coupled to triple quadrupole or tandem-in-time platforms operating in negative electrospray ionization mode with multiple reaction monitoring (MRM), as the required or recommended analytical technique. PFAS analysis is, at its core, an LC–MS/MS problem.<h4>The Sample Preparation Bottleneck</h4>Chemists who have worked with PFAS methods understand the particular demands they place on sample preparation. The ubiquity of<a target="_blank" rel="noopener noreferrer" href="https://blog.organomation.com/blog/tackling-pfas-contamination-practical-insights-from-epa-537.1-method-development"> PFAS in laboratory materials</a>—PTFE tubing, some SPE sorbents, standard bench supplies—means that blank contamination control is as analytically demanding as the detection itself. EPA 537.1 requires that sample volumes of approximately 250 mL be extracted and reconstituted in as little as 1 mL, creating a 250:1 concentration factor that can expose even trace contamination in the sample processing chain. The installation of a delay column between the LC pump and autosampler to prevent instrument background interference is now standard practice.This is precisely where robust, <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/article/5385">inert nitrogen evaporation </a>systems earn their keep. PFAS workflows that use nitrogen-assisted evaporation to concentrate extracts prior to reconstitution benefit from materials that avoid PTFE and other fluoropolymers that can leach PFAS background—a consideration Organomation addresses in its concentration system designs.The analytical community is also moving beyond targeted PFAS analysis. High-resolution accurate mass (HRAM) spectrometry via Orbitrap technology, paired with non-targeted screening workflows, is gaining traction for the identification of the more than 5,000 currently catalogued PFAS compounds and the novel structures that continue to emerge. LC–MS/MS remains the quantitative gold standard; HRAM provides the discovery layer.<h3>Technological Trends Reshaping the LC–MS/MS Workflow</h3><h4>Artificial Intelligence and Automated Data Interpretation</h4>The datasets generated by modern tandem MS platforms—particularly in omics applications—are too large and too complex for conventional manual review. AI-driven spectral deconvolution, automated peak integration, and AI-assisted hypothesis generation are now embedded in the software suites accompanying leading instruments. <a target="_blank" rel="noopener noreferrer" href="https://www.agilent.com/about/newsroom/presrel/2022/17feb-gp22004.html?srsltid=AfmBOop3warRIaEojXM2YyMML6RXfMIDzE-Wm0h-SiKkkocBeeET2m7u">Agilent’s acquisition of Virtual Control’s ACIES </a>software specifically to automate LC–MS and GC–MS data analysis is emblematic of this direction.For laboratory managers, AI integration means smaller specialized teams can operate high-throughput multi-analyte workflows—but it also means that the front-end sample preparation must be even more reproducible, since algorithmic interpretation amplifies inconsistencies introduced upstream.<h4>Online SPE Coupling and “Chromatography Without Walls”</h4>A significant trend is the integration of solid-phase extraction directly into the HPLC flow path—so-called online SPE–HPLC coupling. Systems that combine extraction and chromatographic separation in a single analytical instrument reduce manual transfer steps, minimize the risk of sample loss or contamination, and dramatically increase throughput. For analytes at very low concentrations, online SPE provides the on-column concentration capability that traditional offline preparation achieves with manual evaporation steps.That said, offline sample preparation—including <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/article/5392">nitrogen-assisted evaporation</a> under controlled conditions, <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/2407">liquid–liquid extraction</a>, and protein precipitation—retains significant advantages in flexibility, matrix handling, and the ability to process sample volumes that exceed online system capacity. The two approaches are increasingly complementary rather than competitive in well-designed analytical laboratories.<h4>High-Purity Solvents and Reference Materials</h4>As detection limits push further into the femtogram range and regulatory methods demand demonstrable blank performance, the quality of analytical consumables—mobile phase solvents, derivatization reagents, reference standards—has moved from background consideration to front-of-mind. Method validation in regulated environments now routinely requires vendor certification of solvent purity at a level that directly interfaces with instrument performance.<h3>The Ever-Present Need for Sample Evaporation</h3>As LC–MS/MS methods push detection limits lower, the analytical burden shifts increasingly upstream. The quality of the concentration, cleanup, and reconstitution steps preceding injection determines whether the instrument’s theoretical sensitivity is achievable in practice.Several specific developments are particularly relevant:<ul><li>ADC and gene therapy characterization workflows require gentle, low-temperature evaporation that preserves protein structure and prevents aggregation prior to LC–MS/MS. Nitrogen evaporation under controlled conditions is the preferred approach.</li><li>PFAS trace analysis demands evaporation systems constructed from PFAS-inert materials, with rigorous attention to avoiding fluoropolymer surfaces throughout the sample path.</li><li>High-throughput pharmaceutical QC driven by reshoring demands parallel processing capability—multi-position evaporators that maintain consistent flow and temperature across all positions simultaneously.</li><li>Multi-omics and metabolomics workflows generate large sample batches that benefit from automated, walk-away evaporation with programmable endpoints to ensure reproducible final volumes across a cohort.</li></ul>Tandem chromatography–mass spectrometry is not merely growing; it is becoming structurally embedded in the analytical workflows of every major regulated industry. The convergence of biopharma complexity, PFAS regulatory mandates, AI-enabled data analysis, and pharmaceutical reshoring is creating a multi-year demand cycle that will require laboratories to invest not only in instruments, but in the entire sample preparation ecosystem that makes those instruments perform.For analytical chemists, the practical takeaway is this: as mass spectrometry sensitivity continues to advance, the sample preparation step becomes the binding constraint on method performance. Whether you are developing a new PFAS method to meet EPA 1633, characterizing an ADC’s drug-to-antibody ratio, or running a 500-sample metabolomics cohort overnight, the reliability and cleanliness of your concentration and cleanup workflow determines the quality of every data point that follows.&nbsp;

The Continued Rise of Tandem Chromatography–Mass Spectrometry

<h3>A Practical Guide to Getting the Most from Syringe Filters: Tips, Tricks, and Common Pitfalls</h3>Syringe filters play a crucial role in chromatography and many other laboratory applications by removing particulate matter before analysis. Proper sample filtration helps protect analytical instruments, extends column lifetime, and improves data quality. However, selecting an unsuitable filter—or using one incorrectly—can introduce contamination, reduce filtration efficiency, or even compromise analytical results. The following recommendations will help you avoid common mistakes and ensure reliable filtration every time.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_Avoiding_Common_Syringe_Filter_Mistakes_3_150e8c1c2b.webp" alt="KNAUER: Avoiding Common Syringe Filter Mistakes" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_Avoiding_Common_Syringe_Filter_Mistakes_3_150e8c1c2b.webp 133w," sizes="100vw" width="1276" height="1496"><h4>1. Improper Filter Handling</h4>Using excessive force during filtration or attempting to reuse disposable syringe filters can damage the membrane and increase the risk of sample contamination.<ul><li>Solution: Apply slow, even pressure throughout the filtration process and always dispose of single-use filters after one use. If the flow rate decreases noticeably, replace the filter instead of applying additional force.</li></ul><h4>2. Selecting an Inappropriate Pore Size</h4>Using the wrong pore size may either fail to remove unwanted particles or cause the membrane to clog prematurely, reducing filtration efficiency.<ul><li>Solution: A 0.45 µm membrane is generally suitable for routine particulate removal, while a 0.22 µm membrane is recommended for finer filtration and bacterial removal. Samples with higher viscosity may require a pre-filter to prevent rapid clogging. It is also important to consider the intended analytical technique. For example, 0.22 µm filters are typically preferred for UHPLC and LC-MS applications, whereas 0.45 µm filters are often sufficient for conventional HPLC analyses.</li></ul><h4>3. Choosing the Wrong Membrane Material</h4>Different membrane materials exhibit different chemical resistance. Using an incompatible membrane may lead to degradation of the filter, sample contamination, or complete filtration failure.<ul><li>Solution: Always verify solvent compatibility before filtration. PTFE membranes are an excellent choice for organic solvents, while PES and nylon membranes are better suited to aqueous samples. If compatibility is uncertain, perform a small-scale trial before filtering valuable samples.</li><li>Pro Tip: For additional guidance, see our blog article "How to Choose the Right Membrane for your Syringe Filter", which provides a detailed comparison of membrane materials and their recommended applications.</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_Avoiding_Common_Syringe_Filter_Mistakes_2_e47021fb11.jpg" alt="KNAUER Sepapure® Syringe Filters are available with multiple membrane materials, each identified by a dedicated color code for quick and reliable selection." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_Avoiding_Common_Syringe_Filter_Mistakes_2_e47021fb11.jpg 245w," sizes="100vw" width="1580" height="902"><h4>4. Ignoring Filter Capacity</h4>Using a filter with insufficient capacity can result in rapid membrane blockage, increasing filtration time and reducing laboratory productivity.<ul><li>Solution: When filtering larger sample volumes, choose high-capacity syringe filters or introduce a pre-filtration step. Never force liquid through a clogged membrane, as doing so may damage the filter and negatively affect sample quality.</li></ul><h4>5. Overlooking Sample Adsorption</h4>Certain membrane materials may adsorb analytes of interest, leading to lower recoveries and potentially affecting quantitative results.<ul><li>Solution: For protein samples or other adsorption-sensitive analytes, select membranes with low binding characteristics, such as nylon or glass fiber, whenever appropriate. Performing a small recovery test before routine analysis can help identify potential analyte losses.</li></ul><h4>6. Failing to Optimize Filtration Performance</h4>Slow filtration is more than just an inconvenience—it often indicates that the filtration conditions are not optimal.<ul><li>Solution: If filtration becomes unusually slow, investigate possible causes such as membrane clogging, excessive sample viscosity, or an unnecessarily small pore size. Depending on the sample, dilution or sequential filtration using progressively finer filters may significantly improve performance.</li></ul><h4>Final Thoughts</h4>Selecting the appropriate syringe filter is a straightforward process, but overlooking small details can have a significant impact on analytical performance. Choosing the correct membrane material, pore size, and filtration strategy helps improve laboratory efficiency, protects chromatography systems and columns, and contributes to accurate, reproducible analytical results.With the right syringe filter and proper filtration technique, you can minimize sample preparation problems and maximize confidence in every analysis.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_Avoiding_Common_Syringe_Filter_Mistakes_4_983a15e289.jpg" alt="KNAUER: Sepapure® Syringe Filter Selection" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_Avoiding_Common_Syringe_Filter_Mistakes_4_983a15e289.jpg 245w," sizes="100vw" width="1160" height="627">Happy filtering!

Avoiding Common Syringe Filter Mistakes

News from LabRulezLCMS Library - Week 27, 2026

Article

Product

Application

Academy

Poster

Everything from the world of analytical chemistry in one place. We connect people in solving their problems. At Labrulez you will find all the necessary information easily, quickly and clearly. Stop searching and start finding.

LabRulez

Organomation, founded in 1959, designs and manufactures high-quality nitrogen evaporators and extraction systems. Known for innovation and durability, their lab instruments are used globally for efficient sample preparation with strong customer support.

Organomation

Based in Berlin, KNAUER is a medium-sized, owner-managed company that has been serving the sciences since 1962. We develop and manufacture scientific instruments of superior quality for liquid chromatography, including: Analytical HPLC/UHPLC, Preparative HPLC, Fast protein liquid chromatography (FPLC), Multi-column chromatography/Simulated moving bed (SMB) chromatography. High pressure dosing, in-line detection systems, and osmometry are additional business areas.

KNAUER

Agilent Technologies

Phenomenex

Thermo Fisher Scientific

Waters Corporation

Accelerating Routine Food &amp; Beverage Testing with Optimized Methods
Explore the latest technology and methodology solutions to help you deliver results more easily and efficiently for routine Food and Beverage QC testing for : Sugars, Sugar Substitutes Additives, Vitamins and Amino Acids.
<h3>EPISODE 3 - Water and Fat Soluble Vitamines Analysis</h3>
<h3>Agenda</h3>
<h4>Develop Water and fat soluble Vitamins Analysis</h4>
<ul>
<li>Presenter: To be announced​</li>
</ul>
Abstract: Available soon
<h5>Live Q&amp;A session</h5>
<ul>
<li>Moderator: Cecile Pinto (Food &amp; Environmental Market Development Manager, South Europe - Waters)</li>
</ul>

Waters Corporation: Analysis of Water and Fat Soluble Vitamins in Food and Beverages​

Analysis of Water and Fat Soluble Vitamins in Food and Beverages​

Topics: Develop Water and fat soluble Vitamins Analysis

Water and Fat Soluble Vitamins in Food and Beverages​

Reversed-phased chromatography is both highly selective and versatile. It is no wonder that it is one of the most widely used methods for both small molecules and biomolecules. However, this wide applicability also makes this one of the most diverse methods. From the numerous stationary phases to pore sizes and mobile phases additives, it seems as though there are endless combinations to choose from. From this plethora of choices, how do you develop the best method for your biomolecule?
In this session, we discuss how to make the most of your reversed-phased analysis of biomolecules. From column selection to method conditions and mobile phases, we will discuss how you can optimize these factors for your biomolecule analysis. And, for when things don’t go according to plan, we will discuss how to troubleshoot your method when things go awry.
<blockquote>
Presenter: Melissa Goodlad (Application Engineer, Agilent Technologies, Inc.)
</blockquote>
<blockquote>
Melissa Goodlad is an Application Engineer providing applications assistance and technical support for Agilent’s HPLC columns and consumables. Before joining Agilent, Melissa was completing her PhD in Physical Chemistry at UC Merced studying nanoparticle self-assemblies.
</blockquote>

Agilent Technologies: Reversed-Phase for Biomolecules: From Column Selection to Troubleshooting

Reversed-Phase for Biomolecules: From Column Selection to Troubleshooting

We will discuss how to make the most of your reversed-phased analysis of biomolecules.

RP for Biomolecules: Column Selection & Troubleshooting

Critical to the development and commercialization of a biosimilar is understanding the originator and how its CQAs compare against those of the biosimilar.
Learn more about our solutions that provide high quality peptide mapping, glycan and charge variant data.
<blockquote>
Presenter: Andrew Argo (Strategic Marketing Lead, Waters Corporation)
</blockquote>
<blockquote>
Andrew has held positions across industry with a focus on analytical method development for LC and LCMS applications for products ranging from peptides to gene therapy for almost 10 years. He is currently the strategic marketing lead for the biopharma and new modality portfolios within the chemistry organization, helping to understand these evolving therapeutic areas and customer needs.
</blockquote>

Waters Corporation: Chromatographic techniques for the characterization of CQAs in biosimilars 

Chromatographic techniques for the characterization of CQAs in biosimilars

Solutions that provide high quality peptide mapping, glycan and charge variant data.

Chromatographic techniques for the characterization of CQAs

Learn how to improve assay robustness and reduce the burden associated with migrating methods downstream in the analysis and monitoring of product quality attributes of biopharmaceuticals.
<blockquote>
Presenter: Pawel Bigos (Scientist, Waters Corporation)
</blockquote>
<blockquote>
Pawel is a Scientist at Waters Corporation in the QA/QC Biologics group. He joined Waters in 2022 and has primarily focused on biomolecule separations using Ion-Exchange (IEX) and Size Exclusion (SEC) Chromatography. Prior to Waters, he held positions at Frequency Therapeutics, Novartis, and Symbiotic Research. Pawel received his BS degree in chemistry from the University of South Florida.
</blockquote>

Waters Corporation: Advancing Technology for Better Medicine

Advancing Technology for Better Medicine

Learn how to improve assay robustness and reduce the burden associated with migrating methods downstream.

Key Learning Points:
<ul>
<li>Acquire knowledge about Instrument and mobile phase bottle cleanliness
</li>
<li>Listen in to a systematic breakdown of isolating the unknown peaks
</li>
<li>Acknowledgment of impurity profile for each brand of Formic Acid
</li>
</ul>
Who Should Attend:
<ul>
<li>Any beginner or intermediate HPLC/UV users, or anyone interested in learning more about HPLC systems that inherent contaminants seen in chromatograms</li>
</ul>
<blockquote>
Presenter: Zeshan Aqeel (Senior Application Scientist, Phenomenex)
</blockquote>
<blockquote>
Zeshan Aqeel is part of the Technical Support team at Phenomenex providing problem solving, troubleshooting, and applications support to customers around the world. In this capacity, Zeshan has also assisted in new Phenomenex staff with hands‐on Lab Training and developed and presented many technical seminars as well as demonstrations globally.
</blockquote>
<blockquote>
Mr. Zeshan has over 15 years of chromatography experience and is an expert in practical HPLC method development. After graduating from California State University Northridge with a degree in Biochemistry, he worked at Amgen and Baxter Bioscience as an analytical chemist optimizing LC and LC/MS methods.
</blockquote>
<blockquote>
Joining Phenomenex in 2010 as part of PhenoLogix HPLC/SPE method development team, Zeshan has had a hand in many of the new marketing LC and SPE methods for flagship products such as Kinetex, Strata, Luna Omega and BioZen SEC. Recently, he has been running SEC-MALS and had data presented at 2023 ASMS in Houston.
</blockquote>

Phenomenex: A Formic Acid Case Study – Troubleshooting Unwanted Peaks in HPLC/UV

A Formic Acid Case Study – Troubleshooting Unwanted Peaks in HPLC/UV

Acquire knowledge about Instrument and mobile phase bottle cleanliness.

Troubleshooting Unwanted Peaks in HPLC/UV

Key Learning Points:
<ul>
<li>Understand how to obtain good resolution by utilizing selectivity
</li>
<li>Learn the basics of different stationary phase particle characteristics 
</li>
<li>Discover how to choose different stationary phases based on compound classes
</li>
<li>Find how mobile phase can be used to change selectivity of columns
</li>
</ul>
Who Should Attend:
<ul>
<li>Any LC users who are looking for are looking for a basic overview of Reverse Phase Method Development by looking at different small molecule compound classes</li>
</ul>
<blockquote>
Presenter: Genevieve Hodson (Senior Application Scientist, Phenomenex)
</blockquote>
<blockquote>
Genevieve graduated from the University of Texas with a BS in Chemistry located in her home town of Austin Texas. She spent 2 years of her undergraduate performing research in an Organic Chemistry Lab synthesizing intermediates. Out of school she spent 4 years as an Analytical Chemist in the QC and R&amp;D Department of Cerilliant (a Sigma Millipore Company). There she worked with many analytical instruments but became an expert at LC by performing purity analysis, customer specific methods, validations, qc testing and stability studies on a wide range of small molecules including pharmaceuticals, pesticides, explosives and illegal substances. From there she moved to Los Angeles California where she worked at Johnson and Johnson and then a small dietary supplement company. After Genevieve spent a year living abroad in Israel raising her first son, she moved back to LA where she got hired as a Technical Specialist at Phenomenex. At Phenomenex she enjoys continuing to learn about chromatography every day through helping customer with all their chromatography needs!
</blockquote>

Phenomenex: Understanding Reverse Phase Selectivity for Different Compound Classes

Understanding Reverse Phase Selectivity for Different Compound Classes

Understand how to obtain good resolution by utilizing selectivity.

Understanding Reverse Phase Selectivity

How can you maximize the productivity of your trusted Waters liquid chromatography (LC) systems?
With the easy-to-use Waters Automation Portal, you will be able to automate your ACQUITY and Arc UPLC, UHPLC, and HPLC Systems to reduce time spent on tedious manual procedures, minimize errors, and making your LC and LC-MS workflows more efficient.
In this webinar, hear from Waters partners who will explain how installing the Automation Portal onto their ACQUITY and Arc Sample Managers simplified sample transfer, allowing their scientists to focus on the science instead of tasks.
The Automation Portal is configurable with a wide range of Waters LC and LC-MS systems, reduces space needed for plate loading and transfer, enables automation scheduling with specially designed software, and conveniently works with your preferred integrator to fit into your established workflows.
Join our webinar to see how to streamline your workflows and achieve the quality and consistency your lab demands from its automation partner.
<blockquote>
Presenter: Darcy Shave (Principal Product Manager, Waters Corporation)
</blockquote>
<blockquote>
Darcy Shave is currently a principal product manager in the Small Molecules group at Waters Corporation (Milford, MA, USA), responsible for the purification and hardware automation products. Darcy has been with Waters for over 20 years, starting as an applications chemist in the purification group. From there, he moved into a variety of business development roles before becoming a product manager for purification software about 10 years ago and more recently for the entire purification portfolio. He has a degree in Agricultural Chemistry from the University of Saskatchewan and worked in value added processing of natural products before joining Waters.
</blockquote>
<blockquote>
Presenter: John Canty (Technical Trainer, Biosero)
</blockquote>
<blockquote>
John Canty is the Technical Trainer at Biosero where he educates scientists, automation engineers, and developers in automation solutions. With 19 years of experience in automation, John has held engineering roles at many other companies within the industry, including HighRes Biosolutions, Labcyte, Beckman Coulter, Zymergen, and Illumina. Throughout his career, he has been responsible for the concept, design, programming, and testing of automated equipment and processes. He now uses his expertise to teach others how to master automation software and technology for their own work.
</blockquote>

Waters Corporation: Automate and Streamline Your Lab’s LC and LC-MS Workflows

Automate and Streamline Your Lab’s LC and LC-MS Workflows

We will explain how installing the Automation Portal onto ACQUITY and Arc Sample Managers simplified sample transfer.

The webinar is for novice and experienced LC users, who want to refresh their knowledge on the best practices of working with LC instrumentation.
Join Thermo Fisher Scientific experts on the flow path journey from sample injection to detection to learn useful tips on:
<ul>
<li>Learn what might impact your chromatographic separation and detection, before you start your work.
</li>
<li>How to choose the right configuration and settings to achieve the best results.
</li>
<li>How to keep your system healthy and running.
</li>
</ul>
By attending this webinar, you will learn to optimize LC operations to achieve the best results for your LC separation.
<blockquote>
Presenter: Dr. Susanne Fabel (HPLC Product Marketing Manager, Thermo Fisher Scientific)
</blockquote>
<blockquote>
Susanne Fabel is a Product Marketing Manager in the Chromatography and Mass Spectrometry group at Thermo Fisher Scientific. Her passion is to help develop world-class HPLC instruments to take science one step further. She has more than 15 years of experience in chromatography and holds a PhD in analytical chemistry from the Technical University of Munich.
</blockquote>
<blockquote>
Presenter: Mr. Sumit Verma (Regional Program Manager, Thermo Fisher Scientific)
</blockquote>
<blockquote>
Sumit Verma, is a distinguished Product Market Manager in the Asia-Pacific and Japan region. He is deeply associated with Chromatography and Mass spectrometry at Thermo Fisher Scientific, where he has amassed 18 years of rich experience in the Analytical Industry. Armed with a Post Graduation in Electronics and an Management studies from IIMA India, Sumit embarked on his professional journey as a service engineer before venturing into Sales. Now, as a Product Marketing expert, he thrives on collaborating closely with customers to drive product improvement and innovation, aiming to simplify and enrich their lives.
</blockquote>

Thermo Scientific: Back to Basics – Tips and tricks of HPLC

Back to Basics – Tips and tricks of HPLC

Learn to optimize LC operations to achieve the best results for your LC separation.

Amino Acid Analysis is required in many applications related to foods, dietary supplements and animal feeds and is a fundamental tool for monitoring product QC and compliance with nutritional labeling.
AOAC International has recently published a standardized method (AOAC Official Method 2018.06) for the analysis of total amino acids in infant formulas and adult nutritionals by UHPLC-UV. For some samples, to obtain a full amino acid profile, the samples must first be hydrolyzed. Due to the varied properties of amino acids and diversity of sample matrices, hydrolysis, separation and detection represents an analytical challenge. Learn more about effective hydrolysis, separation and detection of amino acids in dietary supplements, plant-based meats, and pet food during a 3-part webinar series with CEM and Waters.
<blockquote>
Presenter: Alicia Douglas Stell, Ph.D. (Market Development Manager, Applied Markets, CEM Corporation)
</blockquote>
<blockquote>
Dr. Alicia Douglas Stell has worked with CEM for the past 15 years, joining after completing her PhD in Analytical Chemistry. Her extensive background in chromatographic analysis and her mechanical expertise have been integral in the development of both instrumentation and novel applications. In her role as Market Development Manager, she is continuously exploring new applications and markets for innovative technology, focused around sample preparation.
</blockquote>
<blockquote>
Presenter: Benedict Liu (Product Specialist, Organic Solutions, CEM Corporation)
</blockquote>
<blockquote>
Benedict Liu graduated from UNC Chapel Hill in 2018 with a bachelor&#39;s degree in chemistry and mathematics. He joined CEM soon after and has been with the company for 5 years serving as an applications chemist and product specialist for the Molecular Sample Preparation division. In his time at CEM, Ben has worked to develop solutions for the extraction of organic pollutants in soils and product, microwave amino acid hydrolysis protocols, and automated extraction methods for PFAS in solid and semi-solid matrices.
</blockquote>
<blockquote>
Presenter: Paula Phenix (Principal Product Marketing Manager, Waters Corporation)
</blockquote>
<blockquote>
Paula is a Principal Product Marketing Manager at Waters with a focus on products for amino acid and glycan analysis. Prior to her current role in the Chemistry and Lab Automation Group, she was the Product Marketing Manager for Specialty LC and SFC Systems in the Instruments group. Before joining Waters, she held product management, marketing and sales roles for several companies (Life Technologies, Promega, MilliporeSigma) in the molecular biology, immunology, cell culture and single-use bioprocessing areas. Paula graduated from the University of Delaware with a Bachelor’s degree in Biology and from Johns Hopkins University with a Master’s degree in Business.
</blockquote>
<blockquote>
Presenter: Ravali Alagandula, Ph.D. (Chemistry Market Development Manager, Waters Corporation)
</blockquote>
<blockquote>
Ravali is a Chemistry Market Development Manager at Waters with focus on all chemistry consumables and lab automation products. She holds a Ph. D. in Analytical Chemistry from Cleveland State University. She started her career as an LC applications scientist at Restek, developing LC-MS/MS and sample preparation methods in clinical and life science markets. Most recently, Ravali was a Chemistry Account Manager at Waters supporting key accounts and customers to promote chemistry consumable business in all market areas.
</blockquote>

Waters Corporation: Easy & Efficient Amino Acid Sample Prep followed by Accurate Detection - a look at Wet and Dry Pet Food

Easy & Efficient Amino Acid Sample Prep followed by Accurate Detection - a look at Wet and Dry Pet Food

Learn more about effective hydrolysis, separation and detection of amino acids in dietary supplements, plant-based meats, and pet food.

A look at Wet and Dry Pet Food

Waters Corporation: Easy & Efficient Amino Acid Sample Prep followed by Accurate Detection - a look at Plant-based Meats and Proteins

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Chromatographic techniques for the characterization of CQAs in biosimilars

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