A facile and eco-friendly simultaneous quantification LC-TQ-MS/MS approach for N-Nitroso Moxifloxacin and di-nitroso pyrrolopiperidine in Moxifloxacin tablets and eye drops
A rapid, green LC-QqQ-MS/MS method quantifies N-MOX and DNPP in moxifloxacin tablets and eye drops. Validated per ICH, it ensures safety by detecting trace NDSRIs with minimal environmental impact.
Mo, 28.7.2025
LabRulez
Article | Poster
News from LabRulezLCMS Library - Week 30, 2025
This week we bring you posters by Agilent Technologies / ASMS, Shimadzu / ASMS, Thermo Fisher Scientific / ASMS, Waters Corporation / ASMS and application note by Metrohm!
We, 23.7.2025
LabRulez
Article | Webinars
Webinars LabRulezLCMS Week 30/2025
7 webinars: HPLC Troubleshooting, PFAS in Pharma, Tips for LC Column, SCIEX OS, Water, DMPK & Orbitrap, Bruker news from ASMS.
Mo, 21.7.2025
LabRulez
Scientific article | Science and research
A novel LC-TQ-MS/MS method for quantifying mefenamic acid-NDSRI (N-nitroso drug substance-related impurity) in mefenamic acid tablet and pediatric suspension dosage forms: a comparative study with a cost-effective white, green, and blue UPLC method
Novel LC-MS/MS and UPLC methods quantify NDSRI in mefenamic acid tablets and suspensions with high sensitivity, accuracy, and eco-friendly evaluation via multiple green metrics.
Mo, 21.7.2025
LabRulez
Article | Poster
News from LabRulezLCMS Library - Week 29, 2025
This week we bring you posters by Agilent Technologies / ASMS, Shimadzu / ASMS, Thermo Fisher Scientific / ASMS and Waters Corporation / ASMS!
Systematic method optimisation approach for small molecule imaging on the SELECT SERIES MALDI MRT - Drug mapping in fingerprints, a case study
MALDI-MSI on SELECT SERIES MALDI-MRT was optimized for fingerprint imaging. The method improves resolution and enables detection of drugs like antipsychotics in latent prints.
Mo, 14.7.2025
LabRulez
Article | Poster
News from LabRulezLCMS Library - Week 28, 2025
This week we bring you application note by Agilent Technologies and posters by Shimadzu / ASMS, Thermo Fisher Scientific / ASMS and Waters Corporation / ASMS!
Comprehensive IC-ICP-MS analysis of polyphosphonates and their transformation products
This study aims to develop and validate a rapid IC-ICP-MS method for identifying and quantifying polyphosphonates and their transformation products under environmental conditions.