Benchmarking revealed that the Orbitrap Astral Zoom prototype outperforms the standard Astral MS, sampling more ions per peptide and delivering improved sensitivity and quantitative precision in DIA proteomics.

This week we bring you application notes by Agilent Technologies, Metrohm, Shimadzu and Waters Corporation!

A validated QbD-based RP-HPLC method enables robust, stability-indicating impurity analysis of Elexacaftor, supporting process development and quality control in drug manufacturing.

This week we bring you application notes by Agilent Technologies, Shimadzu and Waters Corporation and technical note by Thermo Fisher Scientific!

LC-HRMS screening combined with temporal clustering identified daily domestic discharge patterns in wastewater, enabling improved interpretation of population chemical exposure.

A novel persistence-directed testing approach combined with nontarget GC-MS and LC-HRMS revealed a significant fraction of persistent chemicals in offshore oil platform produced waters.

7 webinars: automated liquid handling, discovery chemistry, GLP-1, HPLC maintenance, LC workflows, SCIEX OS software, SFE/SFC, UV-Vis, workflow automation

This week we bring you application notes by Agilent Technologies and Waters Corporation, technical note by Shimadzu and poster by Thermo Fisher Scientific / ASMS!

15 webinars: affinity enrichment, biopharma, biomarkers, CQA, contaminant screening, CDMS, ergot alkaloids, LC-MS/MS, mobile phases, mycotoxins, PFAS, plasma proteomics, Raman/UV-Vis, sequence mapping

LC-HRMS detected more prescribed and non-prescribed drugs than immunoassays and would have influenced clinical decisions for 25% of patients, mainly those with opioid-use history.