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Waters
Waters
Waters creates business advantages for laboratory-dependent organizations by delivering ultra performance liquid chromatography (UPLC), high-performance liquid chromatography (HPLC), chromatography columns and chemistry products, mass spectrometry systems, laboratory informatics solutions, and comprehensive service programs to enable significant advancement in healthcare delivery, environmental management, food safety, and water quality.
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Waters Corporation (Europe)
Waters makes scientific ambitions a reality through the application of HPLC, MS and TA instruments, consumables, and informatics as well as industry-leading scientific expertise.
33 1 3048 7200
Waters Xevo TQ-S cronos Triple Quadrupole Mass SpectrometryFrom the inherently robust Xevo family of tandem quadrupole instruments, the Xevo TQ-S cronos provides reliable performance at an attractive price point.
Features

Waters Xevo TQ-S cronos Triple Quadrupole Mass Spectrometry

Transform your Quantitative Capabilities

  • Affordable Reliable Performance

From the inherently robust Xevo family of tandem quadrupole instruments, the Xevo TQ-S cronos provides reliable performance at an attractive price point.

Reliable Performance

Achieve your objectives in full with operational performance you can rely on. A Xevo TQ-S cronos study analyzing mycotoxins in cereal (a complex matrix that can contaminate LC/MS instrumentation) showed consistent performance over 5 days of continuous use with 1,000 injections and only 3-8% relative standard deviation (RSD) for peak areas.

Affordable Performance

Cover your key applications with a robust and cost-efficient instrument that delivers reliable results. The Xevo TQ-S cronos can be applied to key demanding applications such as the quantification of nitrosamines in drug products and quantification of pesticides in fruits, vegetables, and cereals.

Cover a Wider Variety of Compounds in One Analysis

Choose the UniSpray source option to include ESI and non-ESI amenable compounds in one injection rather than changing chromatographic inlet or ionization source to extend your analytical capacity and meet changing demands.

Achieve More with Less

  • The Xevo TQ-S cronos is 2-3X narrower than most other instruments in its class, reducing laboratory space overhead costs.
  • Use of the Xevo TQ-S cronos provides up to 35% lower electrical power consumption and associated heat production than other instruments in its class.

Waters Xevo TQ-S cronos Triple Quadrupole Mass Spectrometry - With benchspace at a premium, choose an instrument designed to maximize performance per square inch..jpgWaters Xevo TQ-S cronos Triple Quadrupole Mass Spectrometry - With benchspace at a premium, choose an instrument designed to maximize performance per square inch..jpg

Reliable Performance

Keeping Variability to a Minimum

Be confident that you will have reliable data over multi-day studies. Two experiments using the Xevo TQ-S cronos provide evidence for the longer-term stability of this instrument. By monitoring peak areas whilst running continuous injections, you can see that the Xevo TQ-S cronos won't let you down.

Experiment 1: 4 mycotoxins in wheat flour showed consistent performance over 5 days of continuous use with 1,000 injections and only 3-8% RSD for peak areas.

Waters Xevo TQ-S cronos Triple Quadrupole Mass Spectrometry: Experiment 1 showing data for mycotoxins in wheat flour.Waters Xevo TQ-S cronos Triple Quadrupole Mass Spectrometry: Experiment 1 showing data for mycotoxins in wheat flour.

Experiment 2: Sulfadimethoxine in protein-precipitated plasma also showed consistent performance over 3 days of continuous use with 1,780 injections and only 4% RSD for peak areas.

Waters Xevo TQ-S cronos Triple Quadrupole Mass Spectrometry: Experiment 2 - Sulfadimethoxine in protein precipitated plasma.Waters Xevo TQ-S cronos Triple Quadrupole Mass Spectrometry: Experiment 2 - Sulfadimethoxine in protein precipitated plasma.

Less than 1% of Waters tandem quadrupole mass spectrometers require a detector replacement on an annual basis.*

*Source: Waters internal data on the service history of its tandem quadrupole mass spectrometers launched between 2006 and 2022

Improving Efficiency

Lower operational costs and improved sustainability

As a leading technology innovator in chromatography, mass spectrometry, and thermal analysis instruments and software, Waters shares a common mission with its customers: to leave the world a better place than we found it. Many of our customers are actively working to address environmental sustainability in balance with the need to continually reduce operational costs. The Xevo TQ-S cronos consumes less electricity than most other instruments in its class and therefore produces less heat – lessening the need for air conditioning and lowering costs.

Table 1: Instrument / Power Consumption (W) / Heat Output (Btu/h)
  • Competitor B / 1,100 / 3,700
  • Waters Xevo TQ-S cronos* / 1,230 / 4,194
  • Competitor A / 1,600 / 5,456
  • Competitor C / 1,960 / 6,500

*Xevo TQ-S cronos Site Preparation Guide

Power and heat outputs for entry tier TQ products, conversion factor 1W = 3.41 Btu/h

Ultimate Productivity

Achieve more with flexible software solutions

In an ever-changing environment, flexibility can help protect against future unknowns. The Xevo TQ-S cronos is available on both our waters_connect and MassLynx™ Software platforms, providing the ultimate flexibility to choose a future-proof solution to meet your lab requirements.

waters_connect: Our modern, app-based software platform, waters_connect, delivers efficiency and usability benefits, including the unique Exception Focused Review (XFR) functionality that can save up to 50% of your data review time, ensuring your lab is as productive as possible.

MassLynx: Our tried and well-established MassLynx Software package delivers market-leading versatility and flexibility for all application areas.

Waters Xevo TQ-S cronos Triple Quadrupole Mass Spectrometry: Convert data into meaningful results with waters_connect and MassLynx.Waters Xevo TQ-S cronos Triple Quadrupole Mass Spectrometry: Convert data into meaningful results with waters_connect and MassLynx.

Flexibility

Choose the Optimal Separation and Ionization Technique for Your Application

Waters' market-leading separation technologies include the ACQUITY™ UPLC™ family of LC systems. Application flexibility is further enhanced by the range of quickly interchangeable ion source options made possible by universal ion source architecture.

Waters Xevo TQ-S cronos Triple Quadrupole Mass Spectrometry: UPLC/MRM data on Xevo TQ-XS with UniSpray ion source showing improved sensitivity for three compounds that would typically require a change in ionization technique for optimal analysis.Waters Xevo TQ-S cronos Triple Quadrupole Mass Spectrometry: UPLC/MRM data on Xevo TQ-XS with UniSpray ion source showing improved sensitivity for three compounds that would typically require a change in ionization technique for optimal analysis.

UniSpray™ A novel ionization technique, exclusive to Waters, with wide compound coverage and potential sensitivity benefits. With applicability over a broad range of analytes and a simplified probe design, you can spend less time changing sources and performing maintenance, and more time analyzing your samples.

Waters Xevo TQ-S cronos Triple Quadrupole Mass Spectrometry: UniSpray.Waters Xevo TQ-S cronos Triple Quadrupole Mass Spectrometry: UniSpray.

Optimal Support

Ensure Your Success with World-Renowned Services

Waters Service and Support helps maintain system peak performance, minimize downtime, address scientific application challenges, and support stringent compliance requirements.

Waters award-winning consistent quality support and professional services ensure your success wherever your laboratory is located in the world. With Waters Service and Support offerings* for your Xevo TQ-S cronos, you can:

Get up and running quickly 

Get onsite training and consultation to integrate the Xevo TQ-S cronos into your laboratory and assist with data migration and method transfer needs with Waters Professional Services.

Meet your lab’s unique requirements

Protect your high-performance instrument investment with comprehensive  portfolio of service plans such as Waters FlexCHOICE™, which provides access to the most in-depth and up-to-date knowledge of the advanced science and technologies within Waters systems.

Facilitate compliance

Simplify the process of qualification, validation, and recordkeeping so that your business can focus on delivering products to market with Waters Compliance Services – so you can meet the regulations in your industry and in the countries where you conduct business.

Reduce total cost of ownership

FlexCAPITAL™** is designed to support continuous laboratory operation while satisfying the budgeting challenges of a constantly shifting landscape. Minimize total cost of ownership while optimizing instrument performance and protecting your organization from security risks associated with outdated software platforms.

Leverage your existing technology

With the FlexUP™ technology renewal program, you can upgrade your older tandem quadrupole mass spectrometry system to the Xevo TQ-S cronos – improving performance, results, and productivity while controlling costs and mitigating compliance risk.

*Availability of offerings varies by country. Contact Waters or your local Waters representative for details.

**FlexCAPITAL payment plan options and availability may vary by country. Other restrictions may apply.

Manufacturer
Waters
Waters
Waters creates business advantages for laboratory-dependent organizations by delivering ultra performance liquid chromatography (UPLC), high-performance liquid chromatography (HPLC), chromatography columns and chemistry products, mass spectrometry systems, laboratory informatics solutions, and comprehensive service programs to enable significant advancement in healthcare delivery, environmental management, food safety, and water quality.
Distributor
Waters Corporation (Europe)
Waters makes scientific ambitions a reality through the application of HPLC, MS and TA instruments, consumables, and informatics as well as industry-leading scientific expertise.
33 1 3048 7200
 

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A novel LC-MS/MS assay for low concentrations of creatinine in sweat and saliva to validate biosensors for continuous monitoring of renal function
Scientific article | Science and research

A novel LC-MS/MS assay for low concentrations of creatinine in sweat and saliva to validate biosensors for continuous monitoring of renal function

This study develops and validates an LC-MS/MS assay to quantify low creatinine levels in sweat and saliva, supporting non-invasive biosensor-based kidney function monitoring during haemodialysis.
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