The modular Thermo Scientific Dionex ICS-6000 HPIC system is a highly configurable ion chromatography (IC) system with high pressure capabilities. It enables you to develop and run different methods for a single sample or for different samples simultaneously. The robust design of this system enables operation at up to 5000 psi and produces consistent, reliable results. As a top-of-the-line ion chromatography system, the Dionex ICS-6000 HPIC system is designed to adapt to the needs of users and push the boundaries of what is possible in ion analysis.
Thermo Scientific Dionex ICS-6000 HPIC System.Dionex ICS-6000 HPIC systems come in a variety of configurations, with the ability operate as a single- or dual-channel system to run samples concurrently. This high-pressure IC system can address a full range of IC applications, from 2-D IC for trace-level analysis to high-performance anion-exchange chromatography with pulsed amperometric detection (HPAE-PAD) for complex carbohydrate analysis.
The Dionex ICS-6000 HPIC system is compatible with 4 μm-particle-size IC columns, which are available in 150 or 250 mm lengths. The 150 mm-length columns decrease run times while maintaining chromatographic resolution. The 250 mm-length columns offer improved peak resolution.
For unmatched method reproducibility and accuracy, the system can electrolytically generate high-purity hydroxide, carbonate, bicarbonate, or methanesulfonic acid (MSA) eluents when provided with a source of high-purity deionized water. Using the Dual EGC mode, the Dionex ICS-6000 HPIC system can also generate potassium hydroxide/potassium methanesulfonate (KOH/KMSA) eluents for complex carbohydrate analysis.
Thermo Scientific Dionex ICS-6000 HPIC System: Feutin alditol oligosaccharide analysis using (a) manually prepared eluents (NaOH/NaOAc) (b) Dual EGC mode (KOH/KMSA) with 1 mm column format (c) Dual EGC mode (KOH/KMSA) with 0.4 mm column format.The system is compatible with a wide variety of detectors, including suppressed conductivity, electrochemical, UV-Vis absorbance, inductively coupled plasma mass spectrometry (ICP-MS), and mass spectrometry (MS).
The Dionex ICS-6000 HPIC system is the ideal IC system to work in tandem with mass spectrometry, as it can used for a wide variety of sample analyses. From single quadrupole to high resolution accurate mass (HRAM) Thermo Scientific Orbitrap mass spectrometers, IC-MS analysis provides improved selectivity and higher sensitivity.
Thermo Scientific Dionex ICS-6000 HPIC System: HRAM MS/MS fragments facilitate identification of unknown compounds. IC, combined with HRAM mass spectrometry, is an ideal solution for component identification in non-targeted and unknown workflows. In this figure, identification of lithium-ion battery failure analysis products using HRAM MS/MS offers four-decimal-point accuracy to distinguish between species. The unique fragmentation signature enhances that confidence.
Thermo Scientific Dionex ICS-6000 HPIC System: Targeted MS/MS analysis enables quantitation of molecules in a wide variety of matrices. IC, combined with triple quadrupole mass spectrometry, is an ideal solution for resolving molecules that are often difficult to separate from a matrix using conventional liquid chromatography techniques. In this chromatogram, glyphosate in drinking water is detected at a level of 5 ng/L. The linearity of the assay allows quantitation over 3 orders of magnitude, from 5 ng/L to 1000 ng/L, enabling a wide detection range without having to dilute samples.The Dionex ICS-6000 HPIC system comes with the easy-to-use Thermo Scientific Chromeleon Chromatography Data System (CDS). This software provides powerful control and data processing for IC and offers eWorkflows that make all our essential applications easily accessible. Additionally, the Chromeleon CDS can control mass spectrometry systems, enabling seamless IC-MS analyses.
