Hybrid technology is becoming increasingly important in chromatography and for good reason. Modern analytical laboratories face complex molecules, demanding conditions, and the need for robust, reproducible LC methods. <a target="_blank" rel="noopener noreferrer" href="https://watrex.com/kategorie-produktu/chromatography/hplc-columns/gl-sciences-columns/inertsil/inertsil-hybrid-c18/?utm_source=labrulez&amp;utm_medium=propagace&amp;utm_campaign=labrulez_clanky">Inertsil Hybrid-C18 from GL Sciences</a> was developed as a response to this trend, combining the proven quality of the Inertsil series with the new possibilities offered by hybrid organic–inorganic silica materials. Read on to learn what makes hybrid columns unique and what advantages they bring.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Watrex_GL_hybrid_uvod_AJ_5b1fd0e166.jpg" alt=" Watrex: Special promotion on new Inertsil Hybrid-C18 columns from Watrex Prague." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Watrex_GL_hybrid_uvod_AJ_5b1fd0e166.jpg 245w," sizes="100vw" width="1600" height="900"><h4>Hybrid Technology: A New Level of Stability&nbsp;</h4><a target="_blank" rel="noopener noreferrer" href="https://watrex.com/kategorie-produktu/chromatography/hplc-columns/gl-sciences-columns/inertsil/inertsil-hybrid-c18/?utm_source=labrulez&amp;utm_medium=propagace&amp;utm_campaign=labrulez_clanky">Inertsil Hybrid-C18</a> is a reversed-phase C18 column engineered with hybrid silica gel that combines inorganic silica with organic components. This construction provides exceptional chemical stability.&nbsp;<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Watrex_GL_obr_2_afb06cdb89.jpg" alt="Watrex: Hybrid Technology: A New Level of Stability&nbsp;" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Watrex_GL_obr_2_afb06cdb89.jpg 245w," sizes="100vw" width="1600" height="522"><h5>Key Features&nbsp;</h5><ul><li>pH range 1–12 – stable performance under both acidic and basic conditions&nbsp;</li><li>Compatible with LC/MS and LC/MS/MS&nbsp;</li><li>High durability and long lifetime&nbsp;</li><li>Low bleed suitable for sensitive detection&nbsp;</li><li>USP L1 (C18) classification&nbsp;</li></ul>Thanks to these characteristics, the column performs reliably across a wide range of applications where conventional silica-based materials may fail.&nbsp;<blockquote><a target="_blank" rel="noopener noreferrer" href="https://watrex.com/kategorie-produktu/chromatography/hplc-columns/gl-sciences-columns/inertsil/inertsil-hybrid-c18/?utm_source=labrulez&amp;utm_medium=propagace&amp;utm_campaign=labrulez_clanky">View the full column offering HERE&nbsp;</a></blockquote><h4>A Legacy of Quality: From Silica Synthesis to the Final Column&nbsp;</h4>GL Sciences manufactures Inertsil columns entirely in-house, from the synthesis of the base silica to the final packing. This vertically integrated process, established in 1994, ensures:<ul><li>outstanding quality,&nbsp;</li><li>minimal lot-to-lot variability,&nbsp;</li><li>reliability and consistency across production batches.&nbsp;</li></ul><a target="_blank" rel="noopener noreferrer" href="https://watrex.com/kategorie-produktu/chromatography/hplc-columns/gl-sciences-columns/inertsil/inertsil-hybrid-c18/?utm_source=labrulez&amp;utm_medium=propagace&amp;utm_campaign=labrulez_clanky">Inertsil Hybrid-C18</a> was developed for users who require high durability, a wide operational pH range, and stable performance even under strongly basic conditions.&nbsp;<h4>Impact of pH on Selectivity: Stability Across the Entire pH Range&nbsp;</h4>Changes in mobile-phase pH significantly influence analyte retention and selectivity. With conventional columns, operating outside the optimal pH range often results in degradation, loss of efficiency, or inconsistent retention times.&nbsp;The hybrid material used in <a target="_blank" rel="noopener noreferrer" href="https://watrex.com/kategorie-produktu/chromatography/hplc-columns/gl-sciences-columns/inertsil/inertsil-hybrid-c18/?utm_source=labrulez&amp;utm_medium=propagace&amp;utm_campaign=labrulez_clanky">Inertsil Hybrid-C18</a>, however, enables:&nbsp;<ul><li>stable chromatographic performance,&nbsp;</li><li>excellent reproducibility,&nbsp;</li><li>high efficiency even during long-term operation.&nbsp;</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Watrex_GL_obr_3_0b5faf00f7.jpg" alt="Watrex: Impact of pH on Selectivity" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Watrex_GL_obr_3_0b5faf00f7.jpg 245w," sizes="100vw" width="1600" height="747"><h4>Exceptional High-pH Durability (pH 11.5)&nbsp;</h4>Basic mobile phases are typically destructive for traditional C18 columns. Hybrid technology significantly improves resistance to alkaline conditions.&nbsp;<h5>Advantages at pH 11.5</h5><ul><li>no loss of theoretical plates&nbsp;</li><li>preserved peak shapes&nbsp;</li><li>no silica dissolution&nbsp;</li><li>reliable separation even during long-term exposure&nbsp;</li></ul>This durability makes it possible to develop methods that would be difficult or impractical to run on conventional silica columns.&nbsp;<h4>Outstanding Lot-to-Lot Reproducibility&nbsp;</h4>Three tested production lots of <a target="_blank" rel="noopener noreferrer" href="https://watrex.com/kategorie-produktu/chromatography/hplc-columns/gl-sciences-columns/inertsil/inertsil-hybrid-c18/?utm_source=labrulez&amp;utm_medium=propagace&amp;utm_campaign=labrulez_clanky">Inertsil Hybrid-C18</a> showed virtually identical retention times and peak shapes. As a result:&nbsp;<ul><li>method robustness is ensured&nbsp;</li><li>revalidation when switching lots is unnecessary&nbsp;</li></ul><h4>Broad Application Range&nbsp;</h4>The column delivers excellent peak shapes for:&nbsp;<ul><li>basic compounds (without tailing)&nbsp;</li><li>acidic compounds (stable retention)&nbsp;</li><li>metal-coordinating analytes (no unwanted interactions with metal surfaces)&nbsp;</li></ul>This makes it an ideal choice for pharmaceutical, bioanalytical, and chemical laboratories.<h4>Hardware Options&nbsp;</h4><a target="_blank" rel="noopener noreferrer" href="https://watrex.com/kategorie-produktu/chromatography/hplc-columns/gl-sciences-columns/inertsil/inertsil-hybrid-c18/?utm_source=labrulez&amp;utm_medium=propagace&amp;utm_campaign=labrulez_clanky">Inertsil Hybrid-C18</a> is available in:&nbsp;<ul><li>stainless steel (SS) hardware&nbsp;</li><li>bioinert PEEK hardware (ideal for sensitive applications and LC/MS)&nbsp;</li><li>custom dimensions, including preparative formats&nbsp;</li></ul>The wide selection of configurations allows the column to be tailored precisely to the needs of any application.&nbsp;<blockquote><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/paper/32431">Download new brochure HPLC, LC/MS Columns Inertsil Hybrid-C18</a></blockquote><h4>Conclusion: Why Choose Inertsil Hybrid-C18&nbsp;</h4><a target="_blank" rel="noopener noreferrer" href="https://watrex.com/kategorie-produktu/chromatography/hplc-columns/gl-sciences-columns/inertsil/inertsil-hybrid-c18/?utm_source=labrulez&amp;utm_medium=propagace&amp;utm_campaign=labrulez_clanky">Inertsil Hybrid-C18 </a>is a modern column designed for today’s analytical challenges. It offers robustness, versatility, and the long-established reliability appreciated by users of the Inertsil series. If you are considering optimizing existing methods, switching to more durable columns, or upgrading chromatographic performance, now is the perfect time.&nbsp;<blockquote>Watrex Prague has prepared a special offer! Until the end of December 2025, we are offering an exclusive 25% discount&nbsp;on all Inertsil Hybrid-C18 columns.&nbsp;</blockquote>Visit our website <a target="_blank" rel="noopener noreferrer" href="https://watrex.com/?utm_source=labrulez&amp;utm_medium=propagace&amp;utm_campaign=labrulez_clanky">www.watrex.com</a> to browse the full range, access technical specifications, and place orders. If you have any questions, feel free to contact us. As the official distributor of GL Sciences, we are happy to assist you with product selection and technical support. For a non-binding quotation, contact us at watrex@watrex.com.

Inertsil Hybrid-C18: Stability Across a Wide pH Range

A team of researchers at IOCB Prague headed by Dr. Tomáš Slanina has developed a new method for labeling molecules with fluorescent dyes that surpasses existing approaches in both precision and stability. The new fluorescent label remains covalently bonded to its target molecule and does not fall apart even under demanding conditions inside living cells. This allows scientists to track labeled molecules over long periods with high reliability – an advantage for research in biology, chemistry, and medicine. The study was published in Angewandte Chemie International Edition.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Tomas_Bellon_UOCHB_Dr_Tomas_Slanina_vedouci_vedecke_skupiny_Redoxni_fotochemie_a_Lucie_Salkova_doktorandka_UOCHB_36ca9e4598.jpg" alt="Tomáš Belloň / IOCB Prague: Dr. Tomáš Slanina, head of the Redox Photochemistry research group, and Lucie Šálková, PhD student, IOCB Prague" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Tomas_Bellon_UOCHB_Dr_Tomas_Slanina_vedouci_vedecke_skupiny_Redoxni_fotochemie_a_Lucie_Salkova_doktorandka_UOCHB_36ca9e4598.jpg 234w," sizes="100vw" width="1600" height="1068">Fluorescent labeling of proteins and peptides enables scientists to determine where a molecule is located in a cell and how its behavior changes over time. Current methods, however, have clear limitations. The label often attaches to an unintended site on the molecule, potentially disrupting its structure and, in extreme cases, even its biological function. Moreover, molecules labeled in this way tend to be unstable and can easily unlabel in the cellular environment.“In our work, we applied a highly precise peptide-labeling approach that uses a two-step chemical reaction triggered by light. This allows us to create exceptionally stable fluorescently labeled molecules,” says Tomáš Slanina.The new method from IOCB Prague combines the best features of existing strategies – namely, precision and outstanding molecular stability.Fluorescent labeling proceeds in two steps. First, the dye attaches to the molecule at a precisely defined position. Then, upon exposure to light, the attached label is “glued” in place, converting a temporary bond into a permanent, chemically robust one.“We call the method Stick and Glue!" explains Lucie Šálková, the study’s first author and a PhD student. “Imagine someone dancing with a glow stick. If the stick isn’t activated, you can’t see it and they disappear into the crowd – they might even drop it. But once they snap it and fasten it to their wrist, they won’t lose it, and you can easily spot where they are. Our method works similarly. First, we attach the fluorescent dye, and only after illuminating it with light do we stabilize it – we glue it to the target molecule. From then on, the molecule can be tracked easily without the dye falling off. Unlike other methods, our glow sticks don’t end up scattered on the floor at the end of the night,” she adds.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/UOCHB_Banka_s_fluorescencne_znacenym_glutathionem_242a93510b.jpg" alt="IOCB: The photo shows a flask containing fluorescently labeled glutathione. Glutathione is a small tripeptide and one of the most important antioxidants in cells – it helps neutralize free radicals and protects cells from oxidative stress. In our research, it served as a model molecule to test a new labeling method. While glutathione consists of three amino acids, by the end of the project, we were able to label a protein containing 583 amino acids. This sample, therefore, represents an important milestone of the project – the moment we confirmed that our method truly works. The image captures the lyophilization step, during which the peptide is being dried after conjugation. The visible transition from yellow to red color is related to changes in the fluorophore’s environment as the sample dries." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_UOCHB_Banka_s_fluorescencne_znacenym_glutathionem_242a93510b.jpg 117w," sizes="100vw" width="1600" height="2133">The innovative labeling method developed at IOCB Prague offers a universal, precise, gentle, and permanent way of attaching fluorescent dyes – suitable for small molecules as well as large peptides and proteins. These highly stable labels allow scientists to monitor the movement of selected biomolecules in cells and study their interactions with their environment. The technology expands the possibilities for research in biology, chemistry, and materials science and may contribute to the development of new diagnostic and therapeutic tools.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Angew_Chem_Int_Ed_Engl_2025_Nov_2e15338_figure_1_36885ae230.jpg" alt="Angew Chem Int Ed Engl. 2025 Nov 2:e15338: Figure 1 - Comparison of different labeling methods: a) iodoacetamide, b) maleimide, and c) MTS and our approach." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Angew_Chem_Int_Ed_Engl_2025_Nov_2e15338_figure_1_36885ae230.jpg 245w," sizes="100vw" width="1344" height="375"><blockquote><h4>The original article</h4><h4><a target="_blank" rel="noopener noreferrer" href="https://onlinelibrary.wiley.com/doi/10.1002/anie.202515338">Thiosulfonate-Derived BODIPY “Stick and Glue” Strategy for Fluorescent Thiol Labeling</a></h4>Lucie Šálková, David Dunlop, B. Buse Tütüncü, Dr. Zdeněk Knejzlík, Dr. Tomáš SlaninaAngew Chem Int Ed Engl. 2025 Nov 2:e15338.&nbsp;<a target="_blank" rel="noopener noreferrer" href="https://doi.org/10.1002/anie.202515338">https://doi.org/10.1002/anie.202515338</a><h6>licensed under <a target="_blank" rel="noopener noreferrer" href="https://creativecommons.org/licenses/by/4.0/">CC-BY 4.0</a></h6></blockquote>

Stick and Glue! Tomáš Slanina and his team introduce a new biomolecule-labeling method for more precise observation of cellular processes

Dive into the world of sample preparation with industry expert Wade Hasenour as he shares invaluable insights on rotary evaporation, centrifugal evaporation, and freeze drying. Learn about the latest advancements, challenges, and future trends in sample prep techniques for chromatography. Discover how to choose the right method for your needs, optimize your workflow, and leverage automation for better results. Whether you're a seasoned chromatographer or just starting out, this video offers essential knowledge to enhance your sample preparation skills and achieve more reliable outcomes in your research.<h3>Video Transcription</h3>Interviewer: Hi Wade, I was hoping you could briefly introduce yourself and tell us about your current role.Wade: Yeah, thanks for having me on here. I currently serve at Genevac as a Regional Sales Manager, and I cover the Midwest, South, and Southeast regions.My career began with a strong foundation in biochemistry. I worked in quality assurance in a lab, then moved into pharmacokinetics and worked in that kind of lab environment as well. After that, I transitioned into a sales role working for Shimadzu, where I specialized in chromatography systems. Later I joined Büchi, where I managed the entire product portfolio. And now I’m at Genevac, where I focus mainly on centrifugal evaporation.Interviewer: As you know, we spend a lot of time here talking about chromatography and mass spectrometry. Today I was hoping we could talk about sample preparation. I’m curious: what are some of the most significant changes or advancements you’ve observed in sample preparation throughout your career?Wade: In sample preparation, the biggest transformation I’ve seen is around robotics and automation. There’s a much stronger focus on it now. Companies are hiring consultants to look at workflows and ask:<ul><li>Where can we improve this?</li><li>How do we make it easier?</li><li>How do we reduce time in production, whether that’s for an API, an oligonucleotide, whatever it may be?</li></ul>The goal is to improve throughput and profitability.While chemists focus on the quality of their work, upper management is pushing for automation and more hands-off approaches. That reduces liability, lowers the chance of people being exposed to hazardous chemicals, and of course, “time is money” for commercial labs and many of our customers.Interviewer: That makes all the sense in the world. I was hoping we could get into sample preparation techniques in general. I’m very familiar with nitrogen blowdown because that’s what Organomation specializes in, but could you walk us through some basic principles of rotary evaporation, centrifugal evaporation, and freeze-drying?Wade: Sure. As a basis, the first thing you need to understand—whether it’s rotary evaporation, centrifugal evaporation, or freeze-drying—is that everything is centered around pressure control.When you reduce the pressure, it becomes easier to evaporate solvents in a more gentle way. All three techniques rely on that, but differ in how much you reduce the pressure and how you apply heat. By controlling pressure, you’re also controlling the effective boiling point and thus the temperature of your sample.With rotary evaporation, the traditional method uses gentle heating via a water bath. Water is a great medium to transfer heat. In terms of efficiency and how well it evaporates, water is an excellent middle ground compared to IR lamps and other heating methods.The rotating flask creates a thin film and large surface area, and the reduced pressure lowers the boiling point so solvents evaporate gently and efficiently. The vapor then goes to a condenser, gets cooled, and ends up in the receiving flask.With centrifugal evaporation, the principle is similar—reduced pressure and heating—but typically the vacuum goes lower. This is especially useful for very temperature-sensitive samples like oligonucleotides, RNA therapeutics, ADCs, peptide linkers, etc.You can, for example, run at around 40 °C at ~8 mbar. You place Falcon tubes or microplates into a rotor and evaporate many samples at once. It’s very high-throughput. Often IR is used for heating, which is gentle but can take longer. The big benefit is that you can process hundreds of samples simultaneously, so per sample, the time can actually be faster than doing them one by one on a rotary evaporator.Both rotary and centrifugal evaporators can dry samples completely and are used at various points in the workflow—synthesis, purification, and formulation.Freeze-drying (lyophilization) is a bit different but still in the same family. You lower the pressure so much that water (or other suitable solvents) goes from solid directly to gas—sublimation—with no liquid phase. This preserves the structure of the sample and is excellent for stability and shelf-life.You can freeze-dry samples in trays, vials, Falcon tubes, flasks, and other formats. The idea is to freeze the sample and then pull off the frozen solvent directly into the gas phase, which is why freezing conditions can strongly influence crystallization and final product characteristics.You often see all three technologies in the same lab: rotary evaporator for synthesis scale-ups or solvent exchange, centrifugal evaporation for high-throughput concentration or dry-down, and freeze-dryers for final formulations and long-term stability.Interviewer: That’s very helpful. It’s always been easy to introduce rotary evaporation as “one sample at a time.” How do you see the transition to centrifugal evaporation in practice?Wade: A common pattern is this: you have a few chemists, each with their own rotary evaporator, doing one or two samples at a time. There’s no serious bottleneck.But once the lab’s throughput increases, they hit that bottleneck—too many samples piling up. That’s when centrifugal evaporation becomes attractive: you can process dozens or hundreds of samples at once.Another factor is solvent behavior. Some harsh or high-boiling solvents, like DMSO, are problematic on a rotary evaporator—they bump easily. Centrifugal evaporators use centrifugal force to help suppress bumping and boiling over, which prevents cross-contamination and sample loss. That centrifugal component is key—extra “gravity” keeps the liquid in place.On a rotary evaporator, high-boiling solvents can be difficult to remove without bumping or risking analyte loss. But in a centrifugal evaporator, you can handle a wide range—from low-boiling to high-boiling solvents—more safely and gently.And that’s really the point: preserving the analyte. When people hear “bumping,” they think “losing sample,” “destroying my yield,” and they’re right to be concerned.Interviewer: You touched on efficiency, sample integrity, and cost-effectiveness. Could you expand on how the different techniques compare in those areas?Wade: Sure. I’ll put on my sales hat here.The first question I have to ask clients—though I try to do it gently—is: What’s your budget and what scale are you working at?<ul><li>If someone says, “I have $5,000,” the realistic option is usually a rotary evaporator.</li><li>Rotary systems can be benchtop or scaled up to industrial sizes.</li><li>Centrifugal evaporators are typically high-throughput lab instruments; you don’t often see warehouse-sized centrifugal systems.</li></ul>So cost-effectiveness is the first filter.Then we talk application:<ul><li>If you’re working with a single low-boiling solvent and just a few samples, rotary evaporation is quick and efficient.</li><li>If you’re working with many samples, mixed solvent systems, or very temperature-sensitive analytes, centrifugal evaporation or freeze-drying might be better.</li></ul>For sample integrity, anything that significantly reduces pressure and allows you to keep temperatures low will help preserve sensitive compounds—proteins, oligos, peptides. That’s where centrifugal evaporation and freeze-drying shine. Rotary evaporation sometimes can’t get the pressure low enough, so bath temperatures or solvent boiling points may end up higher than the sample’s stability limit, and you risk denaturation or degradation.For efficiency, if you only have a few samples, rotary evaporation is hard to beat for speed, especially with water as the heat transfer medium. Genevac also has instruments like the Rocket, which use water to transfer heat and are very efficient for low- to mid-boiling solvents, combining some advantages of both worlds.But if you’ve got 1,000 samples, centrifugal evaporation wins on throughput per sample. The conversation with clients is always:<ul><li>What’s your sample load?</li><li>Which solvents are you using?</li><li>How sensitive is your analyte?</li><li>And what’s your budget?</li></ul>Interviewer: What types of samples or analytes are best suited for each of the main evaporation techniques?Wade: Broadly speaking:<ul><li>Rotary evaporation is ideal for APIs and classic organic synthesis—general solvent removal on flasks, reaction work-up, and straightforward solvent exchanges.</li><li>Centrifugal evaporation is great for mixed solvent systems, temperature-sensitive analytes, and high-throughput workflows: RNA therapeutics, oligonucleotide synthesis, drug screening, diagnostic reagent kits, microplates, etc.</li><li>Freeze-drying is best for biological samples, peptides, and analytes requiring long-term stability or shelf-life. It’s often the final formulation or storage step once purification and concentration are done.</li></ul>Nitrogen blowdown (like Organomation’s systems) fits in as well—especially in workflows where you’re concentrating down to GC vials or small volumes, often after larger-scale evaporation.Interviewer: From a sales perspective, I see many labs still using homemade nitrogen blowdown setups. We’re trying to move them toward dedicated equipment. You must encounter similar situations. Could you share a challenging sample prep scenario and how you dealt with it?Wade: Honestly, the story is often similar: hard solvents and sensitive samples.DMSO is a big one. It doesn’t dry down well on rotary evaporators—it bumps, and people worry about losing sample. We get called in to “save the day” and often customize a solution.Two groups stand out:<ul><li>Oligonucleotides and RNA therapeutics</li><li>Labs working with mixed low- and high-boiling solvents</li></ul>They’re worried about cross-contamination in well plates and maintaining integrity of very sensitive analytes. Competitive technologies sometimes don’t provide enough centrifugal force to keep everything in place, so vapor and droplets can move between wells during evaporation.Our approach with Genevac is to position systems as anti-bumping, gentle evaporators. We add features like inert gas purging, which is useful when people use diethyl ether and other explosive solvents, so you avoid creating hazardous conditions.The real challenge is almost always twofold:<ol><li>Prevent cross-contamination and degradation.</li><li>Improve throughput and consistency compared to existing methods.</li></ol>To solve this, we don’t just impose a “one-size-fits-all” recipe. We ask:<ul><li>What solvents are you using?</li><li>How long does your current process take?</li><li>What problems are you seeing?</li></ul>The hard part isn’t the physics or chemistry—it’s understanding the client’s process and building enough trust so they share details honestly. Once we have that, we often co-develop a configuration or workflow with them. In a few cases, we’ve even created new product options in collaboration with customers.Interviewer: What advice would you give chromatographers who are just starting to explore different sample preparation techniques?Wade: First, something slightly outside sample prep: check solvent miscibility. When I sold chromatography systems, I often saw people using solvent mixtures that would cause problems—locking up LC systems and creating all kinds of issues. Using miscibility charts can save a lot of pain.For sample prep itself:<ul><li>Know your analyte: boiling point, reactivity, and stability.</li><li>Choose your method based on sample sensitivity, solvent volatility, throughput, and budget.</li><li>Don’t hesitate to leverage automation. Consultants and vendors are pushing it for a reason—it reduces manual workload, increases reproducibility, and actually improves job security by letting chemists focus on higher-value work like synthesis and method development.</li></ul>Interviewer: You mentioned consultants. What resources or tools would you recommend for people doing research in this area?Wade: Many instrument companies—Shimadzu, Genevac, Büchi, and others—publish extensive application notes and host webinars. Those are great starting points.There are also:<ul><li>Online learning platforms like Coursera (though not always sample-prep specific)</li><li>Trade magazines and websites like LCGC, which cover chromatography fundamentals and advanced applications</li><li>Professional organizations such as ACS for networking and technical resources</li><li>Classic textbooks on instrumental analysis—many are still only in print, but they’re very solid</li><li>Peer-reviewed articles and instrumentation forums</li></ul>And just as important: talk to other scientists. Many chemists are quite private and hesitate to reach out, but networking can be extremely valuable.Interviewer: We’ve talked a lot about automation already, but how do you see sample prep techniques evolving in the coming years?Wade: We’ll see more compact systems, but the big changes will be AI and automation playing a bigger role across the entire workflow.I’ve already seen robots:<ul><li>Take samples off an RNA synthesizer</li><li>Transfer them to an evaporation station</li><li>Move dried samples into the next instrument</li></ul>There are many micro-steps—cleaning glassware, labeling, reconstitution—where robots can help. Even eliminating one of those bottlenecks can improve throughput significantly.Automation and AI will help:<ul><li>Streamline workflows</li><li>Reduce human error (“person sitting in a chair” error, as I like to joke)</li><li>Maintain compliance and traceability</li><li>Let scientists focus on analysis and interpretation rather than repetitive manual tasks</li></ul>Interviewer: In closing, is there anything else you’d like to share about the importance of sample prep in chromatography?Wade: I’d say: give sample prep the thought it deserves. Choosing the right technique doesn’t just help you reach your goals faster; it also opens up possibilities for more complex and innovative analyses.Sample preparation is the foundation for reliable results. Ensuring consistency and optimizing your workflow are key to success in chromatography and analytical science in general.<blockquote>This text has been automatically transcribed from a video presentation using AI technology. It may contain inaccuracies and is not guaranteed to be 100% correct.</blockquote><blockquote><h4>Concentrating on Chromatography Podcast</h4>Dive into the frontiers of chromatography, mass spectrometry, and sample preparation with host David Oliva. Each episode features candid conversations with leading researchers, industry innovators, and passionate scientists who are shaping the future of analytical chemistry. From decoding PFAS detection challenges to exploring the latest in AI-assisted liquid chromatography, this show uncovers practical workflows, sustainability breakthroughs, and the real-world impact of separation science. Whether you’re a chromatographer, lab professional, or researcher you'll discover inspiring content!You can find Concentrating on Chromatography Podcast in podcast apps:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://open.spotify.com/show/1wZg67rCjoGju4yhqxI3tL">Spotify</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podcasts.apple.com/tz/podcast/concentrating-on-chromatography/id1788429185">Apple podcast</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podscan.fm/podcasts/concentrating-on-chromatography">podscan</a></li></ul>and on <a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/@ChromatographyTalk/videos">YouTube channel</a></blockquote>

Sample Preparation Mastery: Expert Insights on Evaporation Techniques for Chromatography

Article

Product

Video

Scientists

Scientific article

Interview

Science and research

The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences (IOCB Prague) is a leading scientific institution in the Czech Republic, recognized internationally. Its primary mission is basic research in the fields of chemical biology and medicinal chemistry, organic and material oriented chemistry, chemistry of natural compounds, biochemistry and molecular biology, physical chemistry, theoretical chemistry, and analytical chemistry. 

Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences

Organomation, founded in 1959, designs and manufactures high-quality nitrogen evaporators and extraction systems. Known for innovation and durability, their lab instruments are used globally for efficient sample preparation with strong customer support.

Organomation

WATREX Prague is the distributor and producer of HPLC techniques in the Czech Republic and Slovakia. Main Chromatografic and Related Techniques Supported: LC, GPC, IC, IEC, Automated SPE, LC Columns and special column packings, LC method development, Software development, Laboratory Robots.

Watrex Praha

Thermo Scientific™ GENESYS™ 30 Vis Spectrophotometer

Perform both basic and complex analyses with the Thermo Scientific™ GENESYS™ 30 Visible Spectrophotometer, an intuitive, reliable solution for education or in the lab.

<h3>Designed for Users, Designed for Results</h3>The Thermo Scientific ™ GENESYS ™ 30 is the most thoughtfully designed spectrophotometer available today. Its high resolution color display, large sample compartment, and data export options meet modern expectations for students, educators and lab technicians. The GENESYS 30 blends the simplicity to satisfy novice students with the capabilities that labs need for accurate quantitative analysis.<h4>System Benefits:</h4><ul><li>Large sample compartment with front access simplifies sample handling</li><li>High resolution color display</li><li>Outstanding durability in challenging environments thanks to:</li><li>Waterproof screen</li><li>Sealed, rubberized keypad</li><li>Removable, washable sample compartment</li><li>Sloping surfaces that shed spills</li><li>Chemical resistant PC-ABS covers</li><li>3A linear measurement range for concentrated solutions</li><li>Multi-point quant offers higher measurement confidence</li><li>Traditional monochromator paired with advanced electronics delivers outstanding stability</li><li>Scan mode for spectral analysis and interpretation</li><li>Data any way you want it - excellent snap-on thermal printer or USB data export</li><li>Expanded capabilities with optional VISIONlite software</li><li>2-year warranty</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_GENESYS_30_Vis_Spectrophotometer_4_4442fcccc5.jpg" alt="Thermo Scientific™ GENESYS™ 30 Vis Spectrophotometer." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_GENESYS_30_Vis_Spectrophotometer_4_4442fcccc5.jpg 195w," sizes="100vw" width="2103" height="1685"><h3>Modern Power meets Traditional Simplicity</h3><h4>Live Display and Concentration Mode</h4>Replicate the familiar display of absorbance or transmittance, and single standard concentration measurements of prior generation instruments in the GENESYS 30 Live Display mode. All your parameters are set and kept in view on a single screen as the calculated concentration updates every two seconds.<h4>Fixed Mode</h4>Apply a factor to an absorbance measurement at one wavelength, or measure at two wavelengths with two factors and perform addition, subtraction or division of the values. Display results for up ten samples then print, save or clear your data before going on to the next sample series.<h4>Quantitative Analysis with up to Six Standards</h4>Go beyond the basic spectrophotometer by recording and storing up to six standards to calibrate your method. Choose a linear fit with an intercept or forced through zero. Name and save your method on the instrument or back it up to a USB memory device. All data are recorded with an index number (S1 – S10) and a time stamp. The result table accommodates up to ten samples for you to print or save before going on to the next sample series or analysis.<h4>Go negative!</h4>Some methods call for blanking the instrument on a dark standard and reading absorbance in the negative range. Most single beam instruments cannot measure below -0.3A. GENESYS 30 uses advanced signal processing to deliver stable, reliable results down to -3A.<h4>Simple to Sophisticated:</h4>The GENESYS 30 has the flexibility to perform routine analysis one minute and complex analytical methods the next. The custom Analyzer mode enables you to build your formula with up to six wavelengths, six factors, standard arithmetic operators and absorbance values raised to the 2nd or 3rd power. Use the included Windows® application to design your method. Transfer the method to your GENESYS 30 and run it with the touch of a button. Analyzer mode shows your method name and a continuous display of your results. Technicians can write the result down or print it with a time stamp using the printer accessory.<h4>Smarter by Design:&nbsp;</h4>GENESYS 30 offers the convenient SmartStart™ feature that has delighted GENESYS 10S users since its introduction. The SmartStart menu gives you direct access to your 12 favorite methods. Allowing you to work smarter, not harder.<h4>Snap on Printer:&nbsp;</h4>Fast and clear printing when you need it. Add printing capability to your instrument. The snap-on thermal printer installs in moments.&nbsp;<h4>Quick and Simple Lamp Replacement:&nbsp;</h4>No need to remove the cover, just loosen two screws, slide out the old lamp fitting and slide a new one back in. Everything is pre-aligned, just let the new lamp warm up and go back to work.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_GENESYS_30_Vis_Spectrophotometer_3_82082740d3.jpg" alt="Thermo Scientific™ GENESYS™ 30 Vis Spectrophotometer: Quick and simple lamp replacement." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_GENESYS_30_Vis_Spectrophotometer_3_82082740d3.jpg 197w," sizes="100vw" width="1737" height="1376"><h3>At Home in the Instructional Laboratory</h3>GENESYS spectrophotometers are core teaching instruments in chemistry and biology laboratories around the world. The Thermo Scientific™ GENESYS™ 30 allows students and teachers to focus on examining scientific data and learning scientific concepts instead of learning instrumentation.<h4>Easy to Teach, Easy to Learn&nbsp;</h4>Clearly labeled, uniquely colored keys simplify instrument operation. New users require little or no training.<h4>Get Working – Faster!</h4>Large, color digital screen and numeric keypad help you set up methods faster. Simplified software interface gives users maximum control and efficiency.<h4>Designed for Today, Built for Tomorrow – Inside and Out!</h4>On the inside, GENESYS 30 uses advanced optics, electronics and signal processing to deliver superior measurement performance for its class. On the outside, GENESYS 30 presents a tough exterior built to last for years in the most demanding environments.<ul><li>Resistant to spills</li><li>Removable and washable sample compartment</li><li>The sample compartment lid<ul><li>stays where you put it - open or closed</li><li>has a magnetic latch to hold it closed during measurements</li><li>is customer-replaceable should it get broken through abuse</li></ul></li></ul><h4>Simple and Familiar</h4>Open the Live Display application with a single button-press to monitor the absorbance or transmittance live – just like a GENESYS 20 or SPECTRONIC 20. The spectrum indicator shows the color of light being absorbed.<h4>Special support for OD 600 and test-tube measurements</h4>For measurements in test-tubes, the test-tube holder accessory accommodates 100mm x 13mm test-tubes with the lid closed. Or add the tall test-tube adaptor to use larger diameter, taller tubes (up to 150mm, 6 inches) with the lid open. Special OD600 mode for cell growth measurements. Select it from the Home menu and go! No method setup required.<h4>Scanning: Simple and Fast</h4>Find peaks in the spectrum of your sample by scanning across the spectrum in any range from 325nm to 1100nm with 1nm precision and noise-free peaks up to 3A. Use the cursor and zoom controls to identify λmax.<h4>Data you can use</h4><ul><li>Print your scan and stick it into a lab notebook using the printer accessory and optional self-stick printer paper.</li><li>Save the data points of your scan to a USB memory device and load the data into a spreadsheet or graphing program for optimal reporting.</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_Thermo_Scientific_Genesys_30_USB_stick_A_c45fd86787.jpg" alt="Thermo Scientific™ GENESYS™ 30 Vis Spectrophotometer: USB stick." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Pragolab_Thermo_Scientific_Genesys_30_USB_stick_A_c45fd86787.jpg 181w," sizes="100vw" width="543" height="469"><h3>VISIONlite Software</h3>For users who need the power of computerized data analysis, optional Thermo Scientific™ VISIONlite™ software pairs a simple user interface with a wider range of options for experiment design and data analysis.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Genesys_spectrophotometers_ae282fe726.jpg" alt="Thermo Scientific - Genesys spectrophotometers: VISIONlite Software." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Genesys_spectrophotometers_ae282fe726.jpg 239w," sizes="100vw" width="1422" height="928"><h4>Scan Application:</h4><ul><li>Automated peak pick and label</li><li>Overlay spectra and print the results</li></ul><h4>Kinetics Application:</h4><ul><li>Data intervals as low as 1 second</li><li>Enzyme rate calculation with factor</li></ul><h4>Quantitative Analysis:</h4><ul><li>Up to 100 standards</li><li>Linear, quadratic or cubic data fits</li></ul><h4>Performance Verification:</h4><ul><li>Full suite of tests to verify performance of your instrument</li><li>Pre-loaded pass/fail limits specific to your instrument</li></ul><h3>GENESYS 30 Accessories</h3><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_GENESYS_30_Vis_Spectrophotometer_59d912ddd3.jpg" alt="Thermo Scientific™ GENESYS™ 30 Vis Spectrophotometer: GENESYS 30 Accessories." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_GENESYS_30_Vis_Spectrophotometer_59d912ddd3.jpg 243w," sizes="100vw" width="1444" height="929"><h3>GENESYS 30 Vis Spectrophotometer Specifications</h3><ul><li>Baseline Flatness: &lt;0.003 A, 325 to 1000 nm smoothed</li><li>Compartments:&nbsp;<ul><li>Accessible from top, front or side</li><li>Able to accommodate cells up to 100mm pathlength</li><li>Available accessory for test-tubes up to 25mm diameter and 150mm height</li><li>Removable, washable sample compartment liner with magnetic placement and hold-down</li></ul></li><li>Connections: USB-A, USB-B</li><li>Description: GENESYS 30 VIS Spectrophotometer with EU Power Cable</li><li>Dimensions (L x W x H): 35.5 x 38.5 x 19.5 cm</li><li>Drift: &lt;0.002 A/hr. (At 500 nm after 2 hr. warmup.) Typical &lt;0.004 A/hr. after 1 hr. warmup</li><li>Electrical Requirements: External AC to DC converter. Voltage and Frequency (Hz) selected automatically, 100/250 V, 50/60 Hz</li><li>Keypad: Tactile rubber 23 keys with numeric keypad</li><li>Lamp Life: 1000 hrs.</li><li>Noise: (RMS at 500nm. 60 consecutive measurements)<ul><li>≤0.001A at 0A</li><li>≤0.001A at 1A</li><li>≤0.002A at 2A</li></ul></li><li>Optical Design: Single Beam</li><li>Photometric Accuracy: ±0.002 A (0 to 0.3 A), 0.5% of ABS reading (0.301 A to 2.5 A)</li><li>Photometric Display: -3A to +3A, 0 to 200 000 %T, 0 to 9 999 999 C</li><li>Photometric Range: -3A to +3A</li><li>Photometric Repeatability: ± 0.002 A (Measured at 1.0 A at 546 nm)</li><li>Printer Included: Thermal printer accessory with 80 mm width paper</li><li>Scan Speed: Automatic – up to 1200 nm/min.</li><li>Stray Light: &lt;0.1%T at 340 nm and 400 nm</li><li>Measured using glass cutoff filters or NaNO₂ at 340 nm</li><li>Warranty: 2 years standard with 1 year extension upon registration of the instrument with Thermo Fisher Scientific within 6 months of purchase</li><li>Wavelength Accuracy: ±2 nm</li><li>Wavelength Data Interval: 1 nm</li><li>Wavelength Repeatability: &lt; ±1 nm</li><li>Weight (Metric): 7.5 kg</li><li>Detector Type: Silicon Photodiode</li><li>Display: 5 in. 32-bit Color Display, 800 x 480 pixels</li><li>Languages: English, French, German, Spanish, Italian, Portuguese, Russian, Chinese, Japanese, Korean, Thai, Arabic</li><li>Wavelength Range: 325 to 1100 nm</li><li>Unit Size: Each</li></ul>

Thermo Scientific™ GENESYS™ 40 Vis Spectrophotometer

Perform routine measurements for quality control or teaching in the chemistry classroom with rugged Thermo Scientific™ GENESYS 40 Vis Spectrophotometer.

<h4>GENESYS - developed for users, designed for results</h4>Built on the foundation of 60 years of spectroscopy experience, the next generation Thermo Scientific™ GENESYS™ family of Vis/UV-Vis spectrophotometers provides exceptional performance with a contemporary design.<ul><li>Start taking measurements immediately with the simple-to-use, high-resolution, color-display start menu</li><li>Exchange samples with ease with large, accessible sample compartment</li><li>Save your data fast any way you want it with multiple data-export options</li></ul>There is a GENESYS spectrophotometer you can count on to provide accurate, reproducible results for your application requirements.<h3>GENESYS 40 Vis Spectrophotometer</h3>For teaching labs, research labs and industrial QC requiring robust construction, ease-of-use and software capability.<h5>Advanced usability, modern functionality</h5><ul><li>7-inch, high-resolution touchscreen interface</li><li>Local control increases speed and reliability for routine analysis</li><li>Large sample compartment with front access simplifies sample handling</li><li>Wi-Fi ready - save data and methods, print results from on-board control</li></ul><h5>Designed for</h5><ul><li>Chemistry labs</li><li>Routine measurements</li><li>Moderate throughput requirements</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_Thermo_Scientific_Genesys_40_Kyveta_A_7955a6a01a.jpg" alt="Thermo Scientific™ GENESYS™ 40 Vis Spectrophotometer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Pragolab_Thermo_Scientific_Genesys_40_Kyveta_A_7955a6a01a.jpg 234w," sizes="100vw" width="1536" height="1024"><h3>Walk-up convenience</h3>Simple-to-use, touchscreen user interface features the methods and applications most important to you.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Genesys_spectrophotometers_ae282fe726.jpg" alt="Thermo Scientific GENESYS Spectrophotometers" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Genesys_spectrophotometers_ae282fe726.jpg 239w," sizes="100vw" width="1422" height="928"><h5>Flexible computer control</h5>Optional VISIONlite software offers complete control from a Microsoft ® Windows ® computer providing applications for:<ul><li>Scanning</li><li>Quantitative analysis</li><li>Kinetics</li><li>Fixed wavelength measurements</li></ul><h3>GENESYS 40 Vis Spectrophotometer Specifications</h3><ul><li>Baseline Flatness: ±0.005 A</li><li>Compartments:&nbsp;<ul><li>Accessible from top, front or side</li><li>Able to accommodate cells up to 100mm cells</li><li>Available accessory for test tubes up to 25 mm diameter and 150 mm height</li><li>Removable, washable sample compartment liner with magnetic placement and hold-down</li></ul></li><li>Connections:&nbsp;<ul><li>Single USB-A</li><li>Duplex USB-A</li><li>Export data to network or PC via USB, Ethernet, or Wi-Fi USB adaptor, available&nbsp;</li><li>Print via USB, Ethernet or Wi-Fi USB adaptor available</li></ul></li><li>Dimensions (L x W x H): 35.5 x 38.5 x 19.5 cm</li><li>Drift: (At 500 nm after 1 hour warmup) &lt;0.0010 A/hr.</li><li>Electrical Requirements: External AC to DC converter. Voltage and Frequency (Hz) selected automatically, 100/240 V, 50/60 Hz</li><li>Includes: GENESYS 40 Spectrophotometer</li><li>Keypad: Touchscreen</li><li>Lamp Life: &gt;1000 hrs.</li><li>Noise: (RMS at 500 nm 60 consecutive measurements)<ul><li>≤0.00020A at 0A at 260 and 500 nm</li><li>≤0.00030A at 1A at 260 and 500 nm</li><li>≤0.00040A at 2A at 260 and 500 nm</li></ul></li><li>Optical Design: Dual Beam</li><li>Photometric Accuracy: ±0.002 A at 0.5 A, ±0.004 A at 1.0 A, ±0.008 A at 2.0 A</li><li>Photometric Display: -3A to +5A</li><li>Photometric Range: –3A to +3.5A</li><li>Photometric Repeatability: ±0.001A at 1A measured at 1.0A at 546 nm</li><li>Printer Included: Snap-on printer available</li><li>Scan Speed: Automatic – up to 1800 nm/min.</li><li>Stray Light: &lt;0.05%T at 340 nm and 400 nm</li><li>Warranty: 2 yrs std + 1 yr ext upon reg</li><li>Wavelength Accuracy: ±0.5 nm</li><li>Wavelength Data Interval: 0.2 nm, 0.5 nm, 1 nm, 2 nm, 5 nm</li><li>Wavelength Repeatability: &lt; ±0.2 nm</li><li>Weight (Metric): 7.5 kg</li><li>Detector Type: Dual Silicon Photodiodes</li><li>Display: 7 in. High Definition Color Touchscreen, Fixed, 800 x 1280 pixels</li><li>Light Source: Tungsten Halogen</li><li>Spectral Bandwidth: 5 nm</li><li>Wavelength Range: 325 to 1100 nm</li><li>Unit Size: Each</li></ul>

Thermo Scientific™ GENESYS™ 140 Vis Spectrophotometer

Perform quantitative measurements in routine industrial QA/QC or university chemistry labs with the automated and network-capable Thermo Scientific™ GENESYS 140 Vis Spectrophotometer.

<h4>GENESYS - developed for users, designed for results</h4>Built on the foundation of 60 years of spectroscopy experience, the next generation Thermo Scientific™ GENESYS™ family of Vis/UV-Vis spectrophotometers provides exceptional performance with a contemporary design.<ul><li>Start taking measurements immediately with the simple-to-use, high-resolution, color-display start menu</li><li>Exchange samples with ease with large, accessible sample compartment</li><li>Save your data fast any way you want it with multiple data-export options</li></ul>There is a GENESYS spectrophotometer you can count on to provide accurate, reproducible results for your application requirements.<h3>GENESYS 140 Vis Spectrophotometer</h3>For advanced teaching labs, R&amp;D, research and life science applications requiring higher throughput or temperature control.<h5>Elite performance, enhanced capabilities</h5><ul><li>7-inch, high-resolution touchscreen interface</li><li>Local control increases speed and reliability for routine analysis</li><li>Large sample compartment with front access simplifies sample handling</li><li>Wi-Fi ready - save data and methods, print results from on-board control</li></ul><h5>Designed for</h5><ul><li>Chemistry labs</li><li>Routine measurements</li><li>Moderate throughput requirements</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_Thermo_Scientific_vis_spektrofotometr_genesys_140_titul_B_bd2a19cbcb.jpg" alt="Thermo Scientific GENESYS Spectrophotometers" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Pragolab_Thermo_Scientific_vis_spektrofotometr_genesys_140_titul_B_bd2a19cbcb.jpg 225w," sizes="100vw" width="516" height="358"><h3>Walk-up convenience</h3>Simple-to-use, touchscreen user interface features the methods and applications most important to you.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Genesys_spectrophotometers_ae282fe726.jpg" alt="Thermo Scientific: Genesys spectrophotometers" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Genesys_spectrophotometers_ae282fe726.jpg 239w," sizes="100vw" width="1422" height="928"><h5>Flexible computer control</h5>Optional VISIONlite software offers complete control from a Microsoft ® Windows ® computer providing applications for:<ul><li>Scanning</li><li>Quantitative analysis</li><li>Kinetics</li><li>Fixed wavelength measurements</li></ul><h3>GENESYS 140 Vis Spectrophotometer Specifications</h3><ul><li>Baseline Flatness: ±0.005 A</li><li>Compartments: Accommodates (optional):<ul><li>8-position cell changer</li><li>4-position cell changer (long path cells)</li><li>Peltier thermostatted cell holder (20–60 °C)</li><li>Sipper accessory</li><li>Fiber optic probe coupler</li></ul></li><li>Connections:&nbsp;<ul><li>Single USB-A</li><li>Duplex USB-A</li><li>Export data to network or PC via USB, Ethernet, or Wi-Fi USB adaptor, available&nbsp;</li><li>Print via USB, Ethernet or Wi-Fi USB adaptor available</li></ul></li><li>Dimensions (L x W x H): 35.5 x 38.5 x 19.5 cm</li><li>Drift: (At 500 nm after 1 hour warmup) &lt;0.0010 A/hr.</li><li>Electrical Requirements: External AC to DC converter. Voltage and Frequency (Hz) selected automatically, 100/240 V, 50/60 Hz</li><li>Includes: Genesys 140 Spectrophotometer</li><li>Keypad: Touchscreen</li><li>Lamp Life: &gt;1000 hrs.</li><li>Noise: (RMS at 500 nm 60 consecutive measurements)<ul><li>≤0.00020A at 0A at 260 and 500 nm</li><li>≤0.00030A at 1A at 260 and 500 nm</li><li>≤0.00040A at 2A at 260 and 500 nm</li></ul></li><li>Optical Design: Dual Beam</li><li>Photometric Accuracy: ±0.002A at 0.5A, ±0.004A at 1.0 A±0.008 A at 2.0A</li><li>Photometric Display: -3A to +5A</li><li>Photometric Range: –3A to +3.5A</li><li>Photometric Repeatability: ±0.001 A at 1 A measured at 1.0 A at 546 nm</li><li>Printer Included: Snap-on printer available</li><li>Scan Speed: Automatic – up to 1800 nm/min.</li><li>Stray Light: &lt;0.05%T at 340 nm and 400 nm</li><li>Warranty: 2 yrs std + 1 yr ext upon reg</li><li>Wavelength Accuracy: ±0.5 nm</li><li>Wavelength Data Interval: 0.2 nm, 0.5 nm, 1 nm, 2 nm, 5 nm</li><li>Wavelength Repeatability: &lt; ±0.2 nm</li><li>Weight (Metric): 7.5 kg</li><li>Detector Type: Dual Silicon Photodiodes</li><li>Display: 7 in. High Definition Color Touchscreen, Tiltable, 800 x 1280 pixels</li><li>Light Source: Tungsten Halogen</li><li>Spectral Bandwidth: 5 nm</li><li>Wavelength Range: 325 to 1100 nm</li><li>Unit Size: Each</li></ul>

Thermo Scientific™ GENESYS™ 50 UV-Vis Spectrophotometer

Perform routine measurements for quality control or teaching in the chemistry classroom with rugged Thermo Scientific™ GENESYS 50 UV-Vis Spectrophotometer.

<h4>GENESYS - developed for users, designed for results</h4>Built on the foundation of 60 years of spectroscopy experience, the next generation Thermo Scientific™ GENESYS™ family of Vis/UV-Vis spectrophotometers provides exceptional performance with a contemporary design.<ul><li>Start taking measurements immediately with the simple-to-use, high-resolution, color-display start menu</li><li>Exchange samples with ease with large, accessible sample compartment</li><li>Save your data fast any way you want it with multiple data-export options</li></ul>There is a GENESYS spectrophotometer you can count on to provide accurate, reproducible results for your application requirements.<h3>GENESYS 50 UV-Vis Spectrophotometer</h3>For teaching labs, research labs and industrial QC requiring robust construction, ease-of-use and software capability.<h5>Advanced usability, modern functionality</h5><ul><li>7-inch, high-resolution touchscreen interface</li><li>Local control increases speed and reliability for routine analysis</li><li>Large sample compartment with front access simplifies sample handling</li><li>Wi-Fi ready - save data and methods, print results from on-board control</li></ul><h5>Designed for</h5><ul><li>Chemistry labs</li><li>Routine measurements</li><li>Moderate throughput requirements</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_Thermo_Scientific_Genesys_50_Kyveta_bae9677ae0.jpg" alt="Thermo Scientific™ GENESYS™ 50 UV-Vis Spectrophotometer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Pragolab_Thermo_Scientific_Genesys_50_Kyveta_bae9677ae0.jpg 188w," sizes="100vw" width="534" height="443"><h3>Walk-up convenience</h3>Simple-to-use, touchscreen user interface features the methods and applications most important to you.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Genesys_spectrophotometers_ae282fe726.jpg" alt="Thermo Scientific GENESYS Spectrophotometers" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Genesys_spectrophotometers_ae282fe726.jpg 239w," sizes="100vw" width="1422" height="928"><h5>Flexible computer control</h5>Optional VISIONlite software offers complete control from a Microsoft ® Windows ® computer providing applications for:<ul><li>Scanning</li><li>Quantitative analysis</li><li>Kinetics</li><li>Fixed wavelength measurements</li></ul><h3>GENESYS 50 UV-Vis Spectrophotometer Specifications</h3><ul><li>Baseline Flatness: ±0.002 A</li><li>Compartments:&nbsp;<ul><li>Accessible from top, front or side</li><li>Able to accommodate cells up to 100 mm cells</li><li>Available accessory for test-tubes up to 25 mm diameter and 150 mm height</li><li>Removable, washable sample compartment liner with magnetic placement and hold-down</li></ul></li><li>Connections:&nbsp;<ul><li>Single USB-A</li><li>Duplex USB-A</li><li>Export data to network or PC via USB, Ethernet, or Wi-Fi USB adaptor, available</li><li>Print via USB, Ethernet or Wi-Fi USB adaptor available</li></ul></li><li>Dimensions (L x W x H): 35.5 x 38.5 x 19.5 cm</li><li>Drift: (At 500 nm after 1 hour warmup) &lt;0.0005 A/hr.</li><li>Electrical Requirements: External AC to DC converter. Voltage and Frequency (Hz) selected automatically, 100/240 V, 50/60 Hz</li><li>Includes: GENESYS 50 Spectrophotometer</li><li>Keypad: Touchscreen</li><li>Lamp Life: &gt; 5 years typical, 3 years guaranteed</li><li>Noise: (RMS at 500 nm 60 consecutive measurements)<ul><li>≤0.00020A at 0A at 260 and 500 nm</li><li>≤0.00030A at 1A at 260 and 500 nm</li><li>≤0.00040A at 2A at 260 and 500 nm</li></ul></li><li>Optical Design: Dual Beam</li><li>Photometric Accuracy: ±0.002A at 0.5A, ±0.004A at 1.0A, ±0.008 A at 2.0 A</li><li>Photometric Display: -3A to +5A</li><li>Photometric Range: –2A to +3.5A</li><li>Photometric Repeatability: ±0.001 A at 1 A measured at 1.0 A at 546 nm</li><li>Printer Included: Snap-on printer available</li><li>Scan Speed: Slow, medium and fast – up to 1600 nm/min.</li><li>Stray Light: &lt; 1.0%T 198 nm (KCl) , &lt;0.05%T at 220 nm (NaI), &lt;0.03%T at 340 nm (NaNO2)</li><li>Warranty: 2 yrs std + 1 yr ext upon reg</li><li>Wavelength Accuracy: ±0.5 nm</li><li>Wavelength Data Interval: 0.2 nm, 0.5 nm, 1 nm, 2 nm, 5 nm</li><li>Wavelength Repeatability: &lt; ±0.2 nm</li><li>Weight (Metric): 7.5 kg</li><li>Detector Type: Dual Silicon Photodiodes</li><li>Display: 7 in. High Definition Color Touchscreen, Fixed, 800 x 1280 pixels</li><li>Spectral Bandwidth: 2 nm</li><li>Wavelength Range: 190 to 1100 nm</li><li>Unit Size: Each</li></ul>

Thermo Scientific™ GENESYS™ 150 UV-Vis Spectrophotometer

Perform quantitative measurements in routine industrial QA/QC or university chemistry labs with the automated and network-capable Thermo Scientific™ GENESYS 150 UV-Vis Spectrophotometer.

<h4>GENESYS - developed for users, designed for results</h4>Built on the foundation of 60 years of spectroscopy experience, the next generation Thermo Scientific™ GENESYS™ family of Vis/UV-Vis spectrophotometers provides exceptional performance with a contemporary design.<ul><li>Start taking measurements immediately with the simple-to-use, high-resolution, color-display start menu</li><li>Exchange samples with ease with large, accessible sample compartment</li><li>Save your data fast any way you want it with multiple data-export options</li></ul>There is a GENESYS spectrophotometer you can count on to provide accurate, reproducible results for your application requirements.<h3>GENESYS 150 UV-Vis Spectrophotometer</h3>For advanced teaching labs, R&amp;D, research and life science applications requiring higher throughput or temperature control.<h5>Elite performance, enhanced capabilities</h5><ul><li>7-inch, high-resolution touchscreen interface</li><li>Local control increases speed and reliability for routine analysis</li><li>Large sample compartment with front access simplifies sample handling</li><li>Wi-Fi ready - save data and methods, print results from on-board control</li></ul><h5>Designed for</h5><ul><li>Chemistry labs</li><li>Routine measurements</li><li>Moderate throughput requirements</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_Thermo_Scientific_vis_spektrofotometr_genesys_150_titul_B_a202c02cea.jpg" alt="Thermo Scientific™ GENESYS™ 150 Uv-Vis Spectrophotometer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Pragolab_Thermo_Scientific_vis_spektrofotometr_genesys_150_titul_B_a202c02cea.jpg 180w," sizes="100vw" width="415" height="360"><h3>Walk-up convenience</h3>Simple-to-use, touchscreen user interface features the methods and applications most important to you.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Genesys_spectrophotometers_ae282fe726.jpg" alt="Thermo Scientific: Genesys spectrophotometers" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Genesys_spectrophotometers_ae282fe726.jpg 239w," sizes="100vw" width="1422" height="928"><h5>Flexible computer control</h5>Optional VISIONlite software offers complete control from a Microsoft ® Windows ® computer providing applications for:<ul><li>Scanning</li><li>Quantitative analysis</li><li>Kinetics</li><li>Fixed wavelength measurements</li></ul><h3>GENESYS 150 UV-Vis Spectrophotometer Specifications</h3><ul><li>Baseline Flatness: ±0.002 A</li><li>Compartments: Accommodates (optional):<ul><li>8-position cell changer</li><li>4-position cell changer (long path cells)</li><li>Peltier thermostatted cell holder (20–60 °C)</li><li>Sipper accessory</li><li>Fiber optic probe coupler</li></ul></li><li>Connections:&nbsp;<ul><li>Single USB-A</li><li>Duplex USB-A</li><li>Export data to network or PC via USB, Ethernet, or Wi-Fi USB adaptor, available</li><li>Print via USB, Ethernet or Wi-Fi USB adaptor available</li></ul></li><li>Dimensions (L x W x H): 35.5 x 38.5 x 19.5 cm</li><li>Drift: (At 500 nm after 1 hour warmup) &lt;0.0005 A/hr.</li><li>Electrical Requirements: External AC to DC converter. Voltage and Frequency (Hz) selected automatically, 100/240 V, 50/60 Hz</li><li>Includes: Genesys 150 Spectrophotometer</li><li>Keypad: Touchscreen</li><li>Lamp Life: &gt; 5 years typical, 3 years guaranteed</li><li>Noise: (RMS at 500 nm 60 consecutive measurements)<ul><li>≤0.00020A at 0A at 260 and 500 nm</li><li>≤0.00030A at 1A at 260 and 500 nm</li><li>≤0.00040A at 2A at 260 and 500 nm</li></ul></li><li>Optical Design: Dual Beam</li><li>Photometric Accuracy: ±0.002A at 0.5A, ±0.004A at 1.0A, ±0.008 A at 2.0 A</li><li>Photometric Display: -3A to +5A</li><li>Photometric Range: –2A to +3.5A</li><li>Photometric Repeatability: ±0.001 A at 1 A measured at 1.0 A at 546 nm</li><li>Printer Included: Snap-on printer available</li><li>Scan Speed: Slow, medium and fast – up to 1600 nm/min.</li><li>Stray Light: &lt; 1.0%T 198 nm (KCl) , &lt;0.05%T at 220 nm (NaI), &lt;0.03%T at 340 nm (NaNO2)</li><li>Warranty: 2 yrs std + 1 yr ext upon reg</li><li>Wavelength Accuracy: ±0.5 nm</li><li>Wavelength Data Interval: 0.2 nm, 0.5 nm, 1 nm, 2 nm, 5 nm</li><li>Wavelength Repeatability: &lt; ±0.2 nm</li><li>Weight (Metric): 7.5 kg</li><li>Detector Type: Dual Silicon Photodiodes</li><li>Display: 7 in. High Definition Color Touchscreen, Tiltable, 800 x 1280 pixels</li><li>Spectral Bandwidth: 2 nm</li><li>Wavelength Range: 190 to 1100 nm</li><li>Unit Size: Each</li></ul>

Thermo Scientific™ GENESYS™ 180 UV-Vis Spectrophotometer

Perform high throughput quantitative UV-Vis measurements where a double beam is required as a reference cell position with the  Thermo Scientific™ GENESYS™ 180 UV-Visible Spectrophotometer. 

<h4>GENESYS - developed for users, designed for results</h4>Built on the foundation of 60 years of spectroscopy experience, the next generation Thermo Scientific™ GENESYS™ family of Vis/UV-Vis spectrophotometers provides exceptional performance with a contemporary design.<ul><li>Start taking measurements immediately with the simple-to-use, high-resolution, color-display start menu</li><li>Exchange samples with ease with large, accessible sample compartment</li><li>Save your data fast any way you want it with multiple data-export options</li></ul>There is a GENESYS spectrophotometer you can count on to provide accurate, reproducible results for your application requirements.<h3>GENESYS 180 UV-Vis Spectrophotometer</h3>For laboratories requiring double beam with a reference cell position.<h5>High-throughput ready</h5><ul><li>Double-beam optics</li><li>Ideal solution when a reference beam is required, such as for kinetics</li><li>8-cell changer standard</li><li>Make measurements outside the sample compartment without cuvettes using fiber optic coupler and probe</li></ul>Designed for laboratories requiring double beam operation with a reference cell position.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_Thermo_Scientific_vis_spektrofotometr_genesys_180_titul_D_open_90df06abb8.jpg" alt="Thermo Scientific™ GENESYS™ 180 UV-Vis Spectrophotometer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Pragolab_Thermo_Scientific_vis_spektrofotometr_genesys_180_titul_D_open_90df06abb8.jpg 171w," sizes="100vw" width="467" height="427"><h3>Walk-up convenience</h3>Simple-to-use, touchscreen user interface features the methods and applications most important to you.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Genesys_spectrophotometers_ae282fe726.jpg" alt="Thermo Scientific Genesys spectrophotometers" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Genesys_spectrophotometers_ae282fe726.jpg 239w," sizes="100vw" width="1422" height="928"><h5>Flexible computer control</h5>Optional VISIONlite software offers complete control from a Microsoft ® Windows ® computer providing applications for:<ul><li>Scanning</li><li>Quantitative analysis</li><li>Kinetics</li><li>Fixed wavelength measurements</li></ul><h3>GENESYS 180 UV-Vis Spectrophotometer Specifications</h3><ul><li>Baseline Flatness: ±0.002 A</li><li>Compartments:<ul><li>8-position cell changer (standard)</li><li>Also accommodates (optional):<ul><li>4-position cell changer (long path cells)</li><li>Peltier thermostatted cell holder (20–60 °C)</li><li>Sipper accessory</li><li>Fiber optic probe coupler</li></ul></li></ul></li><li>Connections:&nbsp;<ul><li>Single USB-A</li><li>Duplex USB-A</li><li>Export data to network or PC via USB, Ethernet, or Wi-Fi USB adaptor, available</li><li>Print via USB, Ethernet or Wi-Fi USB adaptor available</li></ul></li><li>Dimensions (L x W x H): 35.5 x 38.5 x 19.5 cm</li><li>Drift: (At 500 nm after 1 hour warmup) &lt;0.0005 A/hr.</li><li>Electrical Requirements: External AC to DC converter. Voltage and Frequency (Hz) selected automatically, 100/240 V, 50/60 Hz</li><li>Keypad: Touchscreen</li><li>Lamp Life: &gt; 5 years typical, 3 years guaranteed</li><li>Noise: (RMS at 500 nm 60 consecutive measurements)<ul><li>≤0.00020A at 0A at 260 and 500 nm</li><li>≤0.00030A at 1A at 260 and 500 nm</li><li>≤0.00040A at 2A at 260 and 500 nm</li></ul></li><li>Optical Design: Double Beam</li><li>Photometric Accuracy: ±0.002A at 0.5A, ±0.004A at 1.0A, ±0.008 A at 2.0 A</li><li>Photometric Display: -3A to +5A</li><li>Photometric Range: –2A to +3.5A</li><li>Photometric Repeatability: ±0.001 A at 1 A measured at 1.0 A at 546 nm</li><li>Printer Included: Snap-on printer available</li><li>Scan Speed: Slow, medium and fast – up to 1600 nm/min.</li><li>Stray Light: &lt; 1.0%T 198 nm (KCl) , &lt;0.05%T at 220 nm (NaI), &lt;0.03%T at 340 nm (NaNO2)</li><li>Warranty: 2 yrs std + 1 yr ext upon reg</li><li>Wavelength Accuracy: ±0.5 nm</li><li>Wavelength Data Interval: 0.1 nm, 0.2 nm, 0.5 nm, 1 nm, 2 nm, 5 nm</li><li>Wavelength Repeatability: &lt; ±0.2 nm</li><li>Weight (Metric): 7.5 kg</li><li>Detector Type: Dual Silicon Photodiodes</li><li>Display: 7 in. High Definition Color Touchscreen, Tiltable, 800 x 1280 pixels</li><li>Spectral Bandwidth: 2 nm</li><li>Type: UV-Vis Spectrophotometer</li><li>Wavelength Range: 190 to 1100 nm</li><li>Unit Size: Each</li></ul>

Thermo Scientific BioMate 160 UV-Vis Spectrophotometer

Perform quantitative measurements in life science laboratories with the automated and network-capable Thermo Scientific™ BioMate™ 160 UV-Visible Spectrophotometer. 

Perform quantitative measurements in life science laboratories with the automated and network-capable Thermo Scientific™ BioMate™ 160 UV-Visible Spectrophotometer. The BioMate 160 Spectrophotometer offers pre-programmed assay methods for nucleic acid and protein concentration as well as cell culture measurements. Optimized for usability and performance, this platform features a high-resolution color touchscreen, optional Wi-Fi networking, and a rugged design.The BioMate UV-Vis Spectrophotometer provides automation for high-throughput options and room-light resistance, allowing lid-open operation for improved speed and convenience. Software includes pre-programmed life science methods such as Nucleic Acid A260; Protein A280 and A205; Protein Colorimetric assays and OD600.A full line of accessories, including automated cell changers and cell holders, sipper, and fiber optic probes are designed to simplify sampling and accommodate high throughput measurements and temperature control.<h5>Features:</h5><ul><li>7-inch high-resolution touchscreen user interface</li><li>Pre-programmed life science methods</li><li>Networking capable (Wi-Fi adaptor available)</li><li>Room light resistance for 'open-lid' operation</li><li>Sipper accessory</li><li>Removable, washable sample compartment liner with magnetic placement and hold-down</li><li>Accommodates cells up to 100 mm pathlength</li><li>(Optional) 8-position cell changer with switchable turret</li><li>(Optional) 4-position cell changer (long path cells)</li><li>(Optional) Peltier-thermostatted single cell holder (20 °C - 60 °C)</li></ul><h5>Designed for:</h5><ul><li>Advanced teaching labs</li><li>R&amp;D departments</li><li>Applications requiring high throughput or temperature control</li></ul><h4>Specifications</h4>Instrument Type: UV-Visible Spectrophotometer Optical Design: Dual beam Wavelength Range: 190–1100 nm Spectral Bandwidth: 2 nm Photometric Range: –2 A to +3.5 A Photometric Accuracy: ±0.002 A at 0.5 A, ±0.004 A at 1.0 A, ±0.008 A at 2.0 A Photometric Repeatability: ±0.001 A at 1 A (546 nm) Photometric Display: –3 A to +5 A Noise (RMS at 500 nm):<ul><li>≤0.00020 A at 0 A</li><li>≤0.00030 A at 1 A</li><li>≤0.00040 A at 2 A Drift: &lt;0.0005 A/hr at 500 nm after 1-hour warmup Baseline Flatness: ±0.002 A Stray Light:</li><li>&lt;1.0%T at 198 nm (KCl)</li><li>&lt;0.05%T at 220 nm (NaI)</li><li>&lt;0.03%T at 340 nm (NaNO₂)</li></ul><h5>Wavelength Performance</h5><ul><li>Accuracy: ±0.5 nm</li><li>Repeatability: ±0.2 nm</li><li>Data Interval Options: 0.2, 0.5, 1, 2, 5 nm</li><li>Scan Speed: Slow, medium, fast (up to 1600 nm/min)</li></ul><h5>Display &amp; User Interface</h5><ul><li>Touchscreen: 7 in. high-definition color, tiltable (800 × 1280 px)</li><li>Keypad: Touchscreen interface</li></ul><h5>Connectivity &amp; Data Handling</h5><ul><li>Connections: Single USB-A, Duplex USB-A</li><li>Data Export: USB, Ethernet, Wi-Fi adaptor (optional)</li><li>Printer Support: Snap-on printer (optional), USB/Ethernet/Wi-Fi printing available</li></ul><h5>Sample Compartment Compatibility (Optional Accessories)</h5><ul><li>8-position or 4-position cell changers</li><li>Long path cell changer</li><li>Peltier thermostatted cell holder (20–60 °C)</li><li>Sipper accessory</li><li>Fiber optic probe coupler</li></ul><h5>General Specifications</h5><ul><li>Lamp Life: &gt;5 years typical, 3 years guaranteed</li><li>Detector Type: Dual silicon photodiodes</li><li>Dimensions (L × W × H): 35.5 × 38.5 × 19.5 cm</li><li>Weight: 7.5 kg</li><li>Power Requirements: 100–240 V, 50/60 Hz (auto-selecting via external AC–DC converter)</li><li>Certifications: Certificate of Analysis (COA), Certificate of Conformance (COC)</li><li>Warranty: 2 years standard + 1-year extension upon registration</li><li>Unit Size: Each</li></ul>

Products from category UV-VIS spectrophotometry distributed by Thermo Fisher Scientific (EMEA) - page 1

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